YOSQ - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YOSQ - SPBc2 prophage-derived putative HNH homing endonuclease YosQ

UniProt:	O34479	Sequences: MIRKEVEEAPWWITETGVIISKKLKKPRKTFITPHGYEMIGYTHPKKGTQNYLVHRLVAKYFIYDIPKGMFVNHIDGNKLNNHVRNLEIVTPKENTLHAMKIGLMSGQPGESNSMSKLTNMEATNLIYDLIAGMNNVEAGEKYSLHPRYVSLIRHKRRWKTLWDRIERSTTIA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	173 (156)
Sequences:	817 (760)
Seq/√Len:	60.9

BACSU - YOSQ

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
76_D	81_N	8.015	1.00
73_N	88_E	4.470	1.00
73_N	98_H	3.337	1.00
5_E	12_W	3.081	1.00
12_W	20_I	3.038	1.00
69_G	94_E	2.759	1.00
20_I	25_K	2.439	1.00
99_A	104_L	2.432	1.00
71_F	92_P	2.415	1.00
63_I	84_V	2.227	1.00
55_H	82_N	2.208	1.00
59_A	72_V	2.169	1.00
88_E	98_H	2.125	1.00
65_D	69_G	2.108	1.00
90_V	94_E	2.023	1.00
59_A	63_I	1.996	1.00
65_D	70_M	1.970	1.00
75_I	88_E	1.951	1.00
20_I	27_P	1.879	1.00
90_V	98_H	1.863	1.00
3_R	14_T	1.849	1.00
73_N	90_V	1.833	1.00
77_G	104_L	1.801	1.00
3_R	20_I	1.800	1.00
66_I	89_I	1.745	0.99
13_I	58_V	1.745	0.99
93_K	97_L	1.712	0.99
40_I	54_V	1.695	0.99
13_I	19_I	1.685	0.99
133_G	139_A	1.669	0.99
7_E	60_K	1.649	0.99
14_T	18_V	1.602	0.99
21_S	24_L	1.560	0.99
77_G	99_A	1.540	0.98
65_D	68_K	1.529	0.98
15_E	18_V	1.526	0.98
54_V	58_V	1.522	0.98
78_N	81_N	1.520	0.98
37_Y	79_K	1.517	0.98
91_T	94_E	1.503	0.98
66_I	70_M	1.479	0.98
98_H	104_L	1.414	0.97
76_D	83_H	1.396	0.97
94_E	98_H	1.377	0.97
59_A	89_I	1.307	0.96
77_G	98_H	1.291	0.95
64_Y	67_P	1.282	0.95
73_N	95_N	1.279	0.95
77_G	100_M	1.196	0.93
14_T	20_I	1.167	0.92
3_R	16_T	1.165	0.92
71_F	90_V	1.151	0.92
16_T	83_H	1.113	0.90
77_G	103_G	1.108	0.90
75_I	86_N	1.105	0.90
38_E	82_N	1.084	0.89
137_V	141_E	1.045	0.87
153_I	159_W	1.044	0.87
92_P	96_T	1.044	0.87
100_M	104_L	1.043	0.87
71_F	95_N	1.035	0.87
130_L	154_R	1.034	0.87
11_W	21_S	1.030	0.87
93_K	100_M	1.020	0.86
158_R	161_T	1.015	0.86
101_K	112_S	1.006	0.85
73_N	99_A	1.004	0.85
58_V	84_V	0.995	0.85
18_V	27_P	0.984	0.84
43_T	49_T	0.983	0.84
55_H	74_H	0.978	0.84
152_L	158_R	0.975	0.83
5_E	10_P	0.957	0.82
79_K	104_L	0.956	0.82
140_G	143_Y	0.954	0.82
7_E	13_I	0.953	0.82
127_I	130_L	0.946	0.81
13_I	57_L	0.935	0.81
30_T	38_E	0.931	0.80
52_Y	60_K	0.931	0.80
75_I	98_H	0.913	0.79
95_N	99_A	0.906	0.79
55_H	79_K	0.902	0.78
66_I	69_G	0.901	0.78
120_N	123_A	0.899	0.78
37_Y	55_H	0.897	0.78
152_L	157_R	0.892	0.78
56_R	66_I	0.890	0.77
122_E	125_N	0.890	0.77
3_R	12_W	0.889	0.77
98_H	102_I	0.882	0.77
11_W	42_Y	0.882	0.77
127_I	139_A	0.880	0.77
56_R	89_I	0.869	0.76
96_T	99_A	0.862	0.75
33_T	36_G	0.861	0.75
140_G	145_L	0.855	0.74
32_I	80_L	0.854	0.74
77_G	102_I	0.853	0.74
91_T	95_N	0.850	0.74
74_H	95_N	0.845	0.74
155_H	158_R	0.831	0.72
14_T	27_P	0.830	0.72
149_Y	152_L	0.826	0.72
40_I	57_L	0.826	0.72
6_V	57_L	0.820	0.71
19_I	54_V	0.818	0.71
20_I	23_K	0.810	0.70
5_E	9_A	0.807	0.70
69_G	90_V	0.801	0.70
15_E	62_F	0.800	0.69
19_I	58_V	0.797	0.69
147_P	151_S	0.787	0.68
44_H	48_G	0.786	0.68
56_R	73_N	0.784	0.68
75_I	90_V	0.784	0.68
138_E	141_E	0.780	0.67
135_N	139_A	0.775	0.67
90_V	95_N	0.768	0.66
13_I	82_N	0.767	0.66
139_A	145_L	0.764	0.66
13_I	61_Y	0.764	0.66
123_A	159_W	0.758	0.65
136_N	147_P	0.757	0.65
63_I	66_I	0.756	0.65
151_S	155_H	0.752	0.65
9_A	42_Y	0.747	0.64
37_Y	95_N	0.747	0.64
153_I	161_T	0.744	0.64
129_D	133_G	0.742	0.64
99_A	103_G	0.741	0.63
126_L	139_A	0.735	0.63
64_Y	72_V	0.730	0.62
99_A	105_M	0.730	0.62
67_P	70_M	0.729	0.62
17_G	58_V	0.728	0.62
11_W	89_I	0.728	0.62
73_N	104_L	0.714	0.61
76_D	86_N	0.714	0.61
119_T	122_E	0.712	0.60
129_D	139_A	0.711	0.60
98_H	103_G	0.707	0.60
37_Y	74_H	0.706	0.60
55_H	95_N	0.693	0.58
3_R	18_V	0.692	0.58
152_L	156_K	0.690	0.58
123_A	126_L	0.685	0.57
16_T	20_I	0.676	0.56
63_I	69_G	0.676	0.56
16_T	85_R	0.667	0.55
9_A	44_H	0.662	0.55
65_D	75_I	0.657	0.54
31_F	79_K	0.654	0.54
133_G	142_K	0.653	0.54
58_V	86_N	0.648	0.53
65_D	89_I	0.646	0.53
59_A	65_D	0.644	0.53
145_L	161_T	0.641	0.53
3_R	15_E	0.638	0.52
139_A	143_Y	0.636	0.52
150_V	161_T	0.633	0.52
55_H	87_L	0.626	0.51
72_V	87_L	0.626	0.51
30_T	54_V	0.621	0.50
14_T	62_F	0.621	0.50
149_Y	158_R	0.617	0.50
3_R	62_F	0.617	0.50
156_K	161_T	0.612	0.49
13_I	54_V	0.611	0.49
33_T	39_M	0.608	0.49
69_G	91_T	0.607	0.49
18_V	22_K	0.601	0.48
126_L	159_W	0.592	0.47
149_Y	161_T	0.592	0.47
36_G	80_L	0.589	0.47
31_F	39_M	0.587	0.46
64_Y	89_I	0.586	0.46
21_S	28_R	0.584	0.46
97_L	101_K	0.576	0.45
41_G	51_N	0.574	0.45
97_L	100_M	0.570	0.45
44_H	50_Q	0.568	0.44
64_Y	69_G	0.567	0.44
143_Y	150_V	0.567	0.44
145_L	149_Y	0.567	0.44
135_N	138_E	0.566	0.44
88_E	104_L	0.562	0.44
76_D	85_R	0.562	0.44
74_H	82_N	0.561	0.44
144_S	147_P	0.561	0.44
77_G	97_L	0.556	0.43
19_I	120_N	0.555	0.43
10_P	22_K	0.553	0.43
119_T	123_A	0.552	0.43
41_G	49_T	0.551	0.42
116_S	159_W	0.550	0.42
118_L	122_E	0.549	0.42
13_I	17_G	0.547	0.42
66_I	72_V	0.547	0.42
12_W	22_K	0.546	0.42
150_V	158_R	0.545	0.42
136_N	145_L	0.543	0.42
122_E	133_G	0.540	0.41
60_K	65_D	0.538	0.41
9_A	50_Q	0.538	0.41
52_Y	57_L	0.537	0.41
59_A	84_V	0.535	0.41
121_M	129_D	0.534	0.41
10_P	45_P	0.532	0.40
156_K	160_K	0.530	0.40
35_H	51_N	0.527	0.40
11_W	86_N	0.524	0.39
56_R	59_A	0.523	0.39
153_I	160_K	0.522	0.39
56_R	63_I	0.522	0.39
72_V	89_I	0.521	0.39
135_N	143_Y	0.521	0.39
32_I	38_E	0.520	0.39
117_K	120_N	0.518	0.39
52_Y	61_Y	0.518	0.39
59_A	73_N	0.517	0.39
3_R	27_P	0.515	0.38
55_H	72_V	0.514	0.38
5_E	8_E	0.513	0.38
135_N	150_V	0.512	0.38
117_K	143_Y	0.510	0.38
154_R	157_R	0.508	0.38
64_Y	70_M	0.504	0.37
6_V	42_Y	0.503	0.37
96_T	100_M	0.503	0.37
141_E	145_L	0.503	0.37
126_L	130_L	0.501	0.37
6_V	9_A	0.501	0.37
95_N	103_G	0.500	0.37

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1u3eM	1	0.9769	100	0.207	Contact Map
1a73A	2	0.7572	87	0.899	Contact Map
1tc3C	1	0.2948	85.1	0.902	Contact Map
3frwA	2	0.5434	79.8	0.907	Contact Map
2cobA	1	0.3988	77.1	0.909	Contact Map
1jkoC	1	0.2659	73.8	0.912	Contact Map
2elhA	1	0.4451	70.7	0.914	Contact Map
4dyqA	5	0.3295	69.9	0.914	Contact Map
1uxcA	1	0.2312	67.2	0.916	Contact Map
1hlvA	1	0.3642	64.6	0.917	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0068 seconds.