YFKO - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YFKO - Putative NAD(P)H nitroreductase YfkO

UniProt:	O34475	Sequences: MADLKTQILDAYNFRHATKEFDPNKKVSDSDFEFILETGRLSPSSLGLEPWKFVVVQNPEFREKLREYTWGAQKQLPTASHFVLILARTAKDIKYNADYIKRHLKEVKQMPQDVYEGYLSKTEEFQKNDLHLLESDRTLFDWASKQTYIALGNMMTAAAQIGVDSCPIEGFQYDHIHRILEEEGLLENGSFDISVMVAFGYRVRDPRPKTRSAVEDVVKWV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	221 (197)
Sequences:	7820 (6011)
Seq/√Len:	428.3

ECOLI - NFNB RUTE NFSA YDJA
BACSU - YFKO MHQN YODC YDGI NFRA1 YFHC NFRA2
HALSA - Q9HQZ4
SULSO - Q97VQ3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
22_D	25_K	4.636	1.00
34_F	161_I	4.063	1.00
29_D	57_Q	3.137	1.00
28_S	31_D	3.047	1.00
29_D	33_E	2.914	1.00
25_K	201_Y	2.801	1.00
53_F	150_A	2.732	1.00
164_D	202_R	2.468	1.00
35_I	158_A	2.408	1.00
59_P	63_E	2.392	1.00
64_K	179_I	2.365	1.00
177_H	193_I	2.268	1.00
163_V	201_Y	2.224	1.00
37_E	40_R	2.148	1.00
38_T	157_A	2.000	1.00
151_L	195_V	1.993	1.00
61_F	64_K	1.922	1.00
31_D	163_V	1.917	1.00
31_D	161_I	1.862	1.00
20_E	203_V	1.851	1.00
22_D	203_V	1.817	1.00
7_Q	10_D	1.789	1.00
14_F	159_A	1.763	1.00
68_Y	179_I	1.742	1.00
13_N	41_L	1.723	1.00
68_Y	175_H	1.708	1.00
175_H	178_R	1.707	1.00
155_M	167_P	1.703	1.00
158_A	199_F	1.694	1.00
39_G	154_M	1.672	1.00
155_M	165_S	1.660	1.00
8_I	11_A	1.644	1.00
10_D	14_F	1.636	1.00
8_I	12_Y	1.566	1.00
65_L	176_I	1.563	1.00
155_M	197_V	1.562	1.00
33_E	215_E	1.560	1.00
214_V	218_V	1.559	1.00
6_T	10_D	1.557	1.00
159_A	164_D	1.539	1.00
66_R	77_P	1.537	1.00
61_F	179_I	1.526	1.00
112_Q	116_E	1.526	1.00
59_P	62_R	1.515	1.00
21_F	198_A	1.513	1.00
212_S	216_D	1.476	1.00
60_E	63_E	1.462	1.00
63_E	67_E	1.440	1.00
9_L	13_N	1.435	1.00
35_I	154_M	1.432	1.00
52_K	191_F	1.429	1.00
95_Y	99_Y	1.429	1.00
145_K	148_Y	1.418	1.00
158_A	165_S	1.411	1.00
151_L	197_V	1.382	1.00
35_I	199_F	1.380	1.00
35_I	163_V	1.355	1.00
17_A	166_C	1.350	1.00
147_T	194_S	1.346	1.00
74_K	78_T	1.320	1.00
38_T	161_I	1.311	1.00
163_V	199_F	1.307	1.00
58_N	61_F	1.304	1.00
64_K	67_E	1.299	1.00
123_E	127_K	1.299	1.00
9_L	38_T	1.296	1.00
149_I	152_G	1.287	1.00
40_R	217_V	1.272	1.00
172_Q	175_H	1.255	1.00
9_L	161_I	1.251	1.00
36_L	218_V	1.246	1.00
53_F	83_V	1.245	1.00
26_K	57_Q	1.212	1.00
99_Y	103_H	1.211	1.00
9_L	34_F	1.208	1.00
97_A	101_K	1.203	1.00
99_Y	102_R	1.201	1.00
101_K	105_K	1.200	1.00
145_K	169_E	1.174	1.00
27_V	163_V	1.173	1.00
12_Y	153_N	1.171	1.00
31_D	201_Y	1.136	1.00
174_D	178_R	1.131	1.00
31_D	34_F	1.117	1.00
33_E	37_E	1.069	1.00
165_S	199_F	1.067	1.00
165_S	197_V	1.052	1.00
74_K	77_P	1.051	1.00
13_N	37_E	1.045	1.00
95_Y	98_D	1.040	1.00
90_A	93_I	1.036	1.00
154_M	197_V	1.034	1.00
154_M	199_F	1.031	1.00
42_S	153_N	1.026	1.00
32_F	199_F	1.020	1.00
21_F	166_C	0.997	1.00
30_S	33_E	0.997	1.00
144_S	194_S	0.993	1.00
140_F	192_D	0.989	1.00
96_N	99_Y	0.986	1.00
27_V	31_D	0.980	1.00
96_N	100_I	0.980	1.00
27_V	201_Y	0.971	1.00
10_D	13_N	0.968	1.00
111_P	114_V	0.963	1.00
107_V	110_M	0.959	1.00
60_E	64_K	0.957	1.00
36_L	39_G	0.956	1.00
175_H	179_I	0.948	1.00
83_V	154_M	0.948	1.00
8_I	156_T	0.946	1.00
33_E	214_V	0.944	1.00
86_L	191_F	0.941	1.00
120_S	123_E	0.917	1.00
45_S	142_W	0.914	1.00
153_N	156_T	0.913	1.00
34_F	38_T	0.904	1.00
7_Q	160_Q	0.902	1.00
123_E	126_Q	0.898	1.00
28_S	201_Y	0.896	1.00
6_T	160_Q	0.893	1.00
110_M	114_V	0.891	1.00
79_A	82_F	0.889	1.00
89_T	92_D	0.889	1.00
63_E	77_P	0.888	1.00
98_D	101_K	0.888	1.00
166_C	198_A	0.880	1.00
202_R	205_D	0.869	1.00
55_V	218_V	0.869	1.00
26_K	59_P	0.868	1.00
36_L	55_V	0.856	1.00
116_E	119_L	0.854	1.00
37_E	214_V	0.849	1.00
113_D	116_E	0.841	1.00
11_A	160_Q	0.839	1.00
34_F	37_E	0.837	1.00
114_V	117_G	0.837	1.00
120_S	124_E	0.836	1.00
20_E	204_R	0.833	1.00
35_I	161_I	0.831	1.00
67_E	71_G	0.829	1.00
45_S	169_E	0.828	1.00
22_D	201_Y	0.827	1.00
64_K	68_Y	0.823	1.00
18_T	206_P	0.821	1.00
63_E	66_R	0.821	1.00
121_K	124_E	0.816	1.00
75_Q	78_T	0.814	1.00
39_G	53_F	0.803	1.00
176_I	193_I	0.801	1.00
116_E	120_S	0.800	1.00
44_S	51_W	0.799	1.00
141_D	145_K	0.798	1.00
177_H	192_D	0.797	1.00
78_T	81_H	0.796	1.00
32_F	81_H	0.794	1.00
77_P	80_S	0.791	1.00
119_L	122_T	0.790	1.00
8_I	160_Q	0.790	1.00
27_V	30_S	0.782	1.00
107_V	111_P	0.781	1.00
135_S	138_T	0.779	1.00
32_F	36_L	0.778	1.00
173_Y	193_I	0.777	1.00
185_L	189_G	0.776	1.00
141_D	144_S	0.775	1.00
167_P	195_V	0.773	1.00
110_M	113_D	0.769	1.00
142_W	169_E	0.769	1.00
85_I	88_R	0.768	1.00
115_Y	118_Y	0.765	1.00
213_A	216_D	0.759	1.00
54_V	86_L	0.758	1.00
54_V	180_L	0.757	1.00
85_I	154_M	0.753	1.00
121_K	126_Q	0.742	1.00
100_I	104_L	0.737	1.00
113_D	117_G	0.736	1.00
98_D	102_R	0.733	1.00
112_Q	115_Y	0.733	1.00
97_A	100_I	0.722	1.00
18_T	202_R	0.721	1.00
185_L	191_F	0.721	1.00
108_K	114_V	0.719	1.00
53_F	85_I	0.717	1.00
157_A	160_Q	0.717	1.00
150_A	217_V	0.709	1.00
188_N	191_F	0.708	1.00
120_S	126_Q	0.694	1.00
73_Q	77_P	0.693	1.00
69_T	196_M	0.692	1.00
56_V	180_L	0.691	1.00
32_F	55_V	0.686	1.00
122_T	126_Q	0.685	1.00
145_K	194_S	0.685	1.00
124_E	127_K	0.682	1.00
56_V	61_F	0.682	1.00
87_A	91_K	0.679	1.00
144_S	148_Y	0.678	1.00
88_R	91_K	0.678	1.00
54_V	191_F	0.676	1.00
71_G	175_H	0.668	1.00
80_S	84_L	0.666	1.00
40_R	53_F	0.662	1.00
176_I	179_I	0.661	1.00
149_I	153_N	0.660	0.99
117_G	121_K	0.657	0.99
20_E	206_P	0.656	0.99
108_K	113_D	0.655	0.99
19_K	75_Q	0.654	0.99
110_M	115_Y	0.653	0.99
146_Q	169_E	0.653	0.99
145_K	195_V	0.651	0.99
68_Y	176_I	0.650	0.99
151_L	167_P	0.650	0.99
73_Q	76_L	0.648	0.99
76_L	79_A	0.647	0.99
118_Y	121_K	0.645	0.99
102_R	107_V	0.644	0.99
144_S	192_D	0.640	0.99
12_Y	160_Q	0.639	0.99
69_T	76_L	0.639	0.99
84_L	196_M	0.628	0.99
51_W	147_T	0.627	0.99
171_F	196_M	0.622	0.99
69_T	176_I	0.622	0.99
85_I	89_T	0.620	0.99
87_A	143_A	0.620	0.99
27_V	32_F	0.620	0.99
55_V	81_H	0.620	0.99
110_M	118_Y	0.618	0.99
100_I	103_H	0.616	0.99
98_D	216_D	0.611	0.99
177_H	185_L	0.611	0.99
65_L	180_L	0.610	0.99
35_I	157_A	0.606	0.99
119_L	123_E	0.605	0.99
30_S	34_F	0.603	0.99
154_M	165_S	0.602	0.99
6_T	11_A	0.598	0.99
105_K	109_Q	0.596	0.99
99_Y	104_L	0.593	0.99
173_Y	177_H	0.587	0.99
82_F	198_A	0.583	0.99
66_R	73_Q	0.579	0.99
75_Q	79_A	0.578	0.99
204_R	207_R	0.576	0.99
79_A	83_V	0.576	0.99
31_D	35_I	0.572	0.99
174_D	177_H	0.572	0.99
44_S	50_P	0.570	0.99
91_K	95_Y	0.569	0.99
13_N	38_T	0.567	0.98
44_S	49_E	0.565	0.98
11_A	156_T	0.561	0.98
185_L	193_I	0.559	0.98
35_I	39_G	0.559	0.98
89_T	192_D	0.558	0.98
212_S	217_V	0.557	0.98
97_A	102_R	0.552	0.98
168_I	198_A	0.551	0.98
148_Y	152_G	0.548	0.98
20_E	205_D	0.543	0.98
102_R	105_K	0.543	0.98
151_L	155_M	0.543	0.98
88_R	92_D	0.535	0.98
22_D	204_R	0.535	0.98
19_K	166_C	0.534	0.98
12_Y	38_T	0.534	0.98
32_F	57_Q	0.534	0.98
107_V	113_D	0.533	0.98
185_L	188_N	0.532	0.98
111_P	115_Y	0.532	0.98
154_M	157_A	0.529	0.98
190_S	193_I	0.528	0.98
108_K	112_Q	0.528	0.98
142_W	145_K	0.525	0.97
180_L	185_L	0.525	0.97
28_S	33_E	0.524	0.97
81_H	84_L	0.523	0.97
61_F	180_L	0.522	0.97
41_L	208_P	0.522	0.97
152_G	156_T	0.521	0.97
45_S	146_Q	0.521	0.97
101_K	104_L	0.519	0.97
117_G	120_S	0.517	0.97
157_A	161_I	0.516	0.97
87_A	90_A	0.510	0.97
110_M	116_E	0.510	0.97
148_Y	167_P	0.510	0.97
16_H	208_P	0.504	0.97
145_K	149_I	0.503	0.97
138_T	142_W	0.503	0.97
61_F	68_Y	0.502	0.97
111_P	117_G	0.501	0.97
177_H	189_G	0.500	0.97

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2hayA	2	0.9774	100	0.227	Contact Map
3ge6A	2	0.9502	100	0.232	Contact Map
3of4A	3	0.9186	100	0.237	Contact Map
4qlxA	2	0.9502	100	0.243	Contact Map
3gbhA	3	0.9457	100	0.244	Contact Map
3gagA	4	0.9276	100	0.247	Contact Map
2h0uA	2	0.8778	100	0.249	Contact Map
3bemA	2	0.9412	100	0.251	Contact Map
1noxA	2	0.905	100	0.252	Contact Map
1icrA	2	0.9367	100	0.255	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0085 seconds.