YOEA - BACSU - GREMLIN Contacts

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YOEA - Probable multidrug resistance protein YoeA

UniProt:	O34474	Sequences: METSQEPLVTQKKSKPSVWRSMSLFLVPLLLSNVLQSVGQLVGMMAVGRWLGVDAVAAVSSFFPLFFLLISFTIGIGSGSSILIGQAYGAKNEERLKAVVGTTLTFTFLLGVVLAVIGSIFTLDILRLMGTPENVIHVSANYARILFYAMPFMFLYFAYTTFLRGTGDSKTPFYTLIVSTVINIALLPVLILGMFGFPKLGIYGSAYATVISTIATFLVLMVYLRKRKHPLQFDKTVRRYLKMDKELLVLLLRLGVPASINMILVSLSEIAVISFVNHYGSNATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANEFDRLKQVIRVGIWLNYIIGGVLIILIYVFSHQILSLFLTEQETLYIAHRLLMITLWSYLLFGNAQIISATMRASGTVLWPTVISIFAIWGVEVPVAFVLSHYTKLEILGVWVGYPAAFAVSLLLIYGYYQFVWKKKQITRLIQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	463 (424)
Sequences:	18332 (13794)
Seq/√Len:	669.9

ECOLI - YEEO DINF MDTK WZXE
BACSU - YOEA YISQ NORM YPNP
HALSA - Q9HMS7 Q9HRF7 Q9HN79 Q9HRF2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
92_N	95_R	4.735	1.00
152_F	214_I	3.888	1.00
60_S	288_G	3.345	1.00
141_N	203_Y	3.332	1.00
85_G	313_A	3.197	1.00
354_L	367_A	3.068	1.00
349_F	352_Q	3.008	1.00
123_L	140_A	2.995	1.00
249_V	253_R	2.941	1.00
168_D	171_T	2.799	1.00
320_E	323_R	2.769	1.00
121_F	124_D	2.695	1.00
123_L	127_R	2.638	1.00
189_V	194_M	2.496	1.00
80_S	103_T	2.483	1.00
245_K	249_V	2.480	1.00
46_A	191_I	2.477	1.00
182_I	215_A	2.464	1.00
145_I	203_Y	2.450	1.00
140_A	144_R	2.401	1.00
87_A	95_R	2.347	1.00
396_T	448_Y	2.347	1.00
46_A	188_P	2.299	1.00
58_A	138_V	2.289	1.00
54_D	134_N	2.233	1.00
20_R	24_L	2.197	1.00
308_V	331_G	2.181	1.00
179_S	216_T	2.145	1.00
175_T	219_V	2.098	1.00
132_P	281_S	2.097	1.00
98_A	244_D	2.089	1.00
426_E	429_G	2.077	1.00
138_V	141_N	2.055	1.00
145_I	206_A	2.053	1.00
329_R	333_W	2.036	1.00
286_A	366_I	2.024	1.00
155_L	217_F	1.999	1.00
361_Q	365_Y	1.993	1.00
315_S	323_R	1.971	1.00
43_G	209_T	1.963	1.00
350_S	372_M	1.961	1.00
149_A	210_V	1.947	1.00
191_I	205_S	1.929	1.00
203_Y	207_Y	1.920	1.00
369_R	428_L	1.913	1.00
200_L	207_Y	1.908	1.00
362_E	365_Y	1.898	1.00
30_L	303_S	1.882	1.00
137_H	141_N	1.875	1.00
53_V	360_E	1.872	1.00
52_G	55_A	1.858	1.00
47_V	205_S	1.857	1.00
87_A	92_N	1.828	1.00
46_A	187_L	1.828	1.00
351_H	368_H	1.824	1.00
107_T	158_A	1.811	1.00
27_V	31_L	1.779	1.00
189_V	193_G	1.762	1.00
194_M	199_K	1.733	1.00
170_K	174_Y	1.733	1.00
218_L	222_V	1.728	1.00
87_A	90_A	1.695	1.00
122_T	140_A	1.695	1.00
148_Y	151_P	1.693	1.00
193_G	199_K	1.690	1.00
181_V	185_A	1.683	1.00
350_S	368_H	1.676	1.00
380_L	439_A	1.671	1.00
175_T	220_L	1.658	1.00
311_F	327_V	1.651	1.00
26_L	307_A	1.640	1.00
145_I	207_Y	1.635	1.00
152_F	217_F	1.629	1.00
316_I	394_S	1.629	1.00
326_Q	329_R	1.622	1.00
127_R	136_I	1.615	1.00
282_N	362_E	1.614	1.00
347_Y	372_M	1.614	1.00
328_I	387_I	1.614	1.00
244_D	247_L	1.596	1.00
326_Q	330_V	1.574	1.00
325_K	329_R	1.573	1.00
316_I	324_L	1.569	1.00
83_L	99_V	1.569	1.00
335_N	382_G	1.567	1.00
187_L	205_S	1.555	1.00
188_P	192_L	1.516	1.00
42_V	184_I	1.511	1.00
351_H	355_S	1.504	1.00
188_P	194_M	1.500	1.00
315_S	320_E	1.482	1.00
118_G	147_F	1.481	1.00
124_D	127_R	1.477	1.00
145_I	210_V	1.470	1.00
115_A	151_P	1.464	1.00
186_L	208_A	1.462	1.00
136_I	140_A	1.452	1.00
122_T	144_R	1.450	1.00
190_L	194_M	1.445	1.00
343_I	347_Y	1.444	1.00
352_Q	355_S	1.425	1.00
185_A	189_V	1.417	1.00
126_L	136_I	1.415	1.00
62_F	143_A	1.414	1.00
159_Y	220_L	1.411	1.00
322_D	326_Q	1.409	1.00
425_L	429_G	1.401	1.00
43_G	183_N	1.400	1.00
123_L	137_H	1.400	1.00
18_V	311_F	1.398	1.00
328_I	390_T	1.398	1.00
396_T	399_W	1.397	1.00
95_R	98_A	1.396	1.00
185_A	188_P	1.395	1.00
19_W	330_V	1.387	1.00
134_N	137_H	1.387	1.00
133_E	137_H	1.385	1.00
443_L	447_G	1.383	1.00
182_I	186_L	1.382	1.00
373_I	432_V	1.379	1.00
127_R	133_E	1.377	1.00
93_E	97_K	1.375	1.00
190_L	200_L	1.370	1.00
174_Y	178_V	1.363	1.00
203_Y	206_A	1.358	1.00
134_N	281_S	1.353	1.00
94_E	98_A	1.348	1.00
57_A	285_A	1.341	1.00
368_H	372_M	1.338	1.00
31_L	173_F	1.338	1.00
35_L	177_I	1.333	1.00
89_G	317_G	1.332	1.00
333_W	337_I	1.328	1.00
47_V	59_V	1.328	1.00
222_V	226_K	1.326	1.00
355_S	364_L	1.320	1.00
87_A	99_V	1.308	1.00
418_V	422_Y	1.305	1.00
406_F	410_G	1.302	1.00
347_Y	375_L	1.302	1.00
86_Q	313_A	1.301	1.00
88_Y	314_Q	1.296	1.00
352_Q	356_L	1.275	1.00
335_N	386_I	1.274	1.00
246_E	249_V	1.270	1.00
55_A	138_V	1.269	1.00
86_Q	90_A	1.264	1.00
88_Y	96_L	1.261	1.00
321_F	325_K	1.257	1.00
175_T	223_Y	1.242	1.00
123_L	136_I	1.236	1.00
398_L	402_V	1.234	1.00
186_L	211_I	1.232	1.00
44_M	292_Q	1.229	1.00
95_R	247_L	1.229	1.00
365_Y	369_R	1.221	1.00
399_W	448_Y	1.220	1.00
344_I	348_V	1.219	1.00
447_G	450_Q	1.216	1.00
354_L	364_L	1.212	1.00
411_V	440_V	1.207	1.00
188_P	191_I	1.207	1.00
183_N	209_T	1.206	1.00
19_W	334_L	1.202	1.00
124_D	128_L	1.200	1.00
49_R	359_T	1.196	1.00
102_T	243_M	1.185	1.00
187_L	208_A	1.185	1.00
51_L	55_A	1.180	1.00
293_V	353_I	1.173	1.00
119_S	144_R	1.163	1.00
243_M	248_L	1.161	1.00
417_F	421_H	1.159	1.00
425_L	432_V	1.154	1.00
102_T	248_L	1.151	1.00
49_R	192_L	1.142	1.00
178_V	219_V	1.141	1.00
115_A	119_S	1.135	1.00
429_G	433_G	1.131	1.00
86_Q	395_G	1.126	1.00
168_D	172_P	1.124	1.00
305_G	389_A	1.120	1.00
58_A	135_V	1.120	1.00
44_M	56_V	1.117	1.00
53_V	282_N	1.116	1.00
283_A	427_I	1.112	1.00
126_L	139_S	1.107	1.00
17_S	20_R	1.096	1.00
419_L	425_L	1.095	1.00
256_V	260_I	1.091	1.00
59_V	202_I	1.088	1.00
190_L	211_I	1.087	1.00
22_M	331_G	1.084	1.00
312_A	324_L	1.083	1.00
106_F	248_L	1.074	1.00
190_L	193_G	1.072	1.00
290_V	370_L	1.066	1.00
54_D	138_V	1.065	1.00
84_I	165_G	1.059	1.00
43_G	187_L	1.056	1.00
414_P	418_V	1.056	1.00
182_I	212_S	1.055	1.00
100_V	162_F	1.055	1.00
364_L	367_A	1.054	1.00
328_I	449_Y	1.049	1.00
366_I	369_R	1.047	1.00
54_D	281_S	1.044	1.00
188_P	193_G	1.044	1.00
337_I	341_V	1.043	1.00
384_A	438_F	1.035	1.00
171_T	223_Y	1.034	1.00
358_L	363_T	1.028	1.00
402_V	406_F	1.024	1.00
89_G	318_A	1.012	1.00
167_G	314_Q	1.006	1.00
410_G	414_P	0.994	1.00
107_T	154_F	0.992	1.00
387_I	449_Y	0.989	1.00
422_Y	425_L	0.988	1.00
103_T	251_L	0.987	1.00
144_R	148_Y	0.985	1.00
23_S	27_V	0.981	1.00
99_V	247_L	0.975	1.00
274_S	278_H	0.974	1.00
115_A	148_Y	0.973	1.00
403_I	445_I	0.972	1.00
415_V	436_A	0.971	1.00
365_Y	368_H	0.971	1.00
391_M	448_Y	0.971	1.00
194_M	200_L	0.968	1.00
108_F	155_L	0.967	1.00
207_Y	210_V	0.963	1.00
303_S	307_A	0.962	1.00
315_S	327_V	0.961	1.00
286_A	363_T	0.958	1.00
330_V	334_L	0.958	1.00
105_T	243_M	0.957	1.00
120_I	124_D	0.954	1.00
351_H	365_Y	0.952	1.00
193_G	200_L	0.950	1.00
122_T	143_A	0.948	1.00
88_Y	166_T	0.945	1.00
177_I	181_V	0.945	1.00
373_I	428_L	0.944	1.00
282_N	366_I	0.940	1.00
340_G	344_I	0.938	1.00
370_L	427_I	0.936	1.00
98_A	247_L	0.935	1.00
120_I	144_R	0.934	1.00
159_Y	217_F	0.934	1.00
250_L	253_R	0.933	1.00
187_L	209_T	0.924	1.00
45_M	48_G	0.921	1.00
86_Q	316_I	0.921	1.00
293_V	346_I	0.918	1.00
324_L	328_I	0.915	1.00
73_T	154_F	0.914	1.00
215_A	219_V	0.913	1.00
40_Q	63_F	0.907	1.00
289_V	357_F	0.904	1.00
437_A	441_S	0.904	1.00
380_L	442_L	0.902	1.00
210_V	214_I	0.901	1.00
168_D	223_Y	0.893	1.00
42_V	183_N	0.887	1.00
29_L	306_I	0.886	1.00
141_N	144_R	0.884	1.00
253_R	398_L	0.882	1.00
163_L	224_L	0.882	1.00
341_V	344_I	0.879	1.00
347_Y	351_H	0.879	1.00
411_V	414_P	0.878	1.00
433_G	437_A	0.876	1.00
186_L	190_L	0.876	1.00
88_Y	93_E	0.876	1.00
109_L	113_V	0.875	1.00
46_A	192_L	0.874	1.00
148_Y	210_V	0.873	1.00
101_G	241_L	0.873	1.00
138_V	202_I	0.872	1.00
80_S	84_I	0.871	1.00
21_S	24_L	0.871	1.00
341_V	345_L	0.869	1.00
362_E	366_I	0.866	1.00
101_G	240_Y	0.863	1.00
332_I	383_N	0.863	1.00
214_I	218_L	0.861	1.00
275_F	416_A	0.860	1.00
277_N	284_T	0.859	1.00
207_Y	211_I	0.856	1.00
264_L	405_I	0.851	1.00
324_L	394_S	0.850	1.00
364_L	368_H	0.846	1.00
226_K	229_H	0.845	1.00
350_S	371_L	0.844	1.00
183_N	187_L	0.844	1.00
174_Y	177_I	0.844	1.00
312_A	393_A	0.843	1.00
116_V	120_I	0.842	1.00
348_V	352_Q	0.841	1.00
61_S	131_T	0.837	1.00
119_S	123_L	0.835	1.00
66_F	146_L	0.830	1.00
287_Y	431_W	0.829	1.00
168_D	227_R	0.828	1.00
416_A	420_S	0.827	1.00
25_F	169_S	0.821	1.00
315_S	318_A	0.818	1.00
428_L	432_V	0.817	1.00
105_T	241_L	0.816	1.00
22_M	330_V	0.816	1.00
283_A	366_I	0.814	1.00
276_V	427_I	0.812	1.00
289_V	367_A	0.811	1.00
260_I	401_T	0.811	1.00
301_A	339_G	0.810	1.00
42_V	180_T	0.810	1.00
275_F	278_H	0.809	1.00
219_V	222_V	0.809	1.00
113_V	117_I	0.809	1.00
35_L	180_T	0.807	1.00
53_V	363_T	0.807	1.00
86_Q	250_L	0.805	1.00
133_E	136_I	0.805	1.00
286_A	367_A	0.805	1.00
135_V	284_T	0.804	1.00
19_W	333_W	0.804	1.00
156_Y	216_T	0.803	1.00
407_A	441_S	0.802	1.00
383_N	442_L	0.797	1.00
292_Q	357_F	0.796	1.00
54_D	135_V	0.796	1.00
312_A	390_T	0.795	1.00
354_L	368_H	0.794	1.00
173_F	177_I	0.790	1.00
159_Y	224_L	0.787	1.00
145_I	148_Y	0.787	1.00
337_I	340_G	0.785	1.00
326_Q	333_W	0.784	1.00
336_Y	340_G	0.783	1.00
304_L	331_G	0.782	1.00
47_V	191_I	0.778	1.00
82_I	86_Q	0.774	1.00
276_V	430_V	0.773	1.00
187_L	191_I	0.771	1.00
286_A	370_L	0.770	1.00
72_F	259_S	0.767	1.00
163_L	220_L	0.766	1.00
347_Y	350_S	0.766	1.00
419_L	429_G	0.766	1.00
234_D	239_R	0.766	1.00
122_T	147_F	0.766	1.00
199_K	203_Y	0.765	1.00
178_V	182_I	0.764	1.00
97_K	240_Y	0.762	1.00
141_N	202_I	0.761	1.00
83_L	254_L	0.761	1.00
323_R	326_Q	0.761	1.00
278_H	421_H	0.759	1.00
57_A	135_V	0.758	1.00
117_I	121_F	0.753	1.00
48_G	56_V	0.752	1.00
255_G	259_S	0.752	1.00
39_G	209_T	0.752	1.00
85_G	165_G	0.751	1.00
312_A	328_I	0.751	1.00
420_S	429_G	0.750	1.00
35_L	38_V	0.749	1.00
84_I	162_F	0.749	1.00
137_H	140_A	0.748	1.00
21_S	314_Q	0.748	1.00
183_N	212_S	0.748	1.00
429_G	432_V	0.747	1.00
263_I	267_L	0.747	1.00
90_A	317_G	0.747	1.00
439_A	443_L	0.746	1.00
32_S	176_L	0.745	1.00
21_S	311_F	0.743	1.00
222_V	225_R	0.743	1.00
279_Y	420_S	0.743	1.00
315_S	324_L	0.742	1.00
58_A	202_I	0.742	1.00
103_T	158_A	0.740	1.00
247_L	250_L	0.739	1.00
373_I	435_P	0.738	1.00
83_L	87_A	0.738	1.00
164_R	172_P	0.735	1.00
51_L	199_K	0.731	1.00
105_T	109_L	0.728	1.00
97_K	234_D	0.728	1.00
331_G	386_I	0.726	1.00
322_D	329_R	0.722	1.00
361_Q	364_L	0.722	1.00
330_V	333_W	0.717	1.00
340_G	379_L	0.715	1.00
275_F	420_S	0.715	1.00
126_L	143_A	0.714	1.00
42_V	46_A	0.709	1.00
221_M	225_R	0.709	1.00
163_L	171_T	0.709	1.00
427_I	431_W	0.706	1.00
171_T	219_V	0.706	1.00
58_A	139_S	0.704	1.00
376_W	379_L	0.703	1.00
41_L	296_Y	0.703	1.00
38_V	42_V	0.700	1.00
121_F	125_I	0.698	1.00
389_A	393_A	0.696	1.00
415_V	419_L	0.694	1.00
19_W	23_S	0.693	1.00
419_L	422_Y	0.692	1.00
250_L	395_G	0.692	1.00
275_F	417_F	0.692	1.00
348_V	351_H	0.692	1.00
304_L	338_I	0.690	1.00
206_A	210_V	0.688	1.00
399_W	403_I	0.688	1.00
349_F	353_I	0.687	1.00
22_M	307_A	0.686	1.00
211_I	214_I	0.686	1.00
336_Y	382_G	0.685	1.00
142_Y	187_L	0.685	1.00
45_M	356_L	0.683	1.00
257_P	401_T	0.683	1.00
322_D	325_K	0.681	1.00
130_G	133_E	0.679	1.00
294_A	378_Y	0.679	1.00
333_W	336_Y	0.678	1.00
123_L	144_R	0.672	1.00
149_A	213_T	0.671	1.00
271_A	413_V	0.669	1.00
116_V	119_S	0.669	1.00
90_A	319_N	0.667	1.00
413_V	417_F	0.666	1.00
254_L	397_V	0.665	1.00
34_V	38_V	0.664	1.00
432_V	435_P	0.660	1.00
273_I	277_N	0.660	1.00
178_V	215_A	0.660	1.00
411_V	415_V	0.657	1.00
316_I	321_F	0.657	1.00
113_V	116_V	0.656	1.00
309_S	392_R	0.656	1.00
200_L	203_Y	0.655	1.00
276_V	287_Y	0.654	1.00
339_G	382_G	0.653	1.00
143_A	147_F	0.652	1.00
95_R	99_V	0.651	1.00
358_L	361_Q	0.651	1.00
190_L	205_S	0.648	1.00
84_I	96_L	0.648	1.00
308_V	312_A	0.647	1.00
350_S	354_L	0.647	1.00
212_S	215_A	0.645	1.00
304_L	335_N	0.644	1.00
98_A	101_G	0.643	1.00
144_R	203_Y	0.643	1.00
159_Y	221_M	0.640	1.00
252_L	256_V	0.639	1.00
47_V	202_I	0.638	1.00
200_L	204_G	0.638	1.00
149_A	152_F	0.637	1.00
26_L	303_S	0.635	1.00
54_D	57_A	0.633	1.00
147_F	150_M	0.633	1.00
148_Y	152_F	0.633	1.00
82_I	254_L	0.632	1.00
135_V	138_V	0.632	1.00
21_S	323_R	0.632	1.00
321_F	324_L	0.631	1.00
298_Q	381_F	0.629	1.00
286_A	431_W	0.629	1.00
108_F	112_V	0.629	1.00
360_E	364_L	0.628	1.00
372_M	376_W	0.628	1.00
338_I	342_L	0.626	1.00
351_H	364_L	0.625	1.00
45_M	49_R	0.624	1.00
47_V	55_A	0.624	1.00
418_V	421_H	0.624	1.00
182_I	211_I	0.620	1.00
51_L	202_I	0.619	1.00
363_T	367_A	0.618	1.00
131_T	277_N	0.616	1.00
79_G	255_G	0.615	1.00
94_E	97_K	0.615	1.00
336_Y	379_L	0.614	1.00
387_I	445_I	0.613	1.00
75_G	259_S	0.612	1.00
279_Y	283_A	0.612	1.00
55_A	201_G	0.611	1.00
142_Y	205_S	0.610	1.00
111_G	147_F	0.607	1.00
39_G	179_S	0.605	1.00
390_T	394_S	0.604	1.00
297_V	342_L	0.602	1.00
39_G	213_T	0.599	1.00
275_F	421_H	0.599	1.00
156_Y	217_F	0.598	1.00
177_I	180_T	0.596	1.00
136_I	139_S	0.596	1.00
119_S	148_Y	0.595	1.00
81_S	161_T	0.594	1.00
444_L	447_G	0.594	1.00
178_V	181_V	0.593	1.00
75_G	309_S	0.593	1.00
358_L	364_L	0.592	1.00
112_V	116_V	0.592	1.00
397_V	401_T	0.592	1.00
192_L	200_L	0.590	1.00
17_S	21_S	0.590	1.00
126_L	140_A	0.589	1.00
334_L	337_I	0.589	1.00
55_A	58_A	0.588	1.00
82_I	313_A	0.588	1.00
300_P	338_I	0.587	1.00
98_A	102_T	0.585	1.00
160_T	164_R	0.585	1.00
147_F	151_P	0.584	1.00
111_G	151_P	0.584	1.00
219_V	223_Y	0.583	1.00
115_A	120_I	0.583	1.00
38_V	180_T	0.582	1.00
126_L	131_T	0.582	1.00
217_F	221_M	0.581	1.00
332_I	336_Y	0.580	1.00
101_G	105_T	0.577	1.00
345_L	349_F	0.577	1.00
56_V	289_V	0.577	1.00
56_V	358_L	0.576	1.00
272_V	430_V	0.576	1.00
134_N	138_V	0.575	1.00
412_E	437_A	0.575	1.00
246_E	250_L	0.574	1.00
283_A	286_A	0.573	1.00
381_F	438_F	0.571	1.00
336_Y	383_N	0.571	1.00
183_N	208_A	0.571	1.00
151_P	214_I	0.570	1.00
76_I	259_S	0.570	1.00
238_R	241_L	0.570	1.00
432_V	436_A	0.569	1.00
129_M	270_I	0.569	1.00
375_L	379_L	0.567	1.00
182_I	185_A	0.566	1.00
314_Q	318_A	0.566	1.00
92_N	98_A	0.565	1.00
414_P	417_F	0.564	1.00
272_V	416_A	0.564	1.00
225_R	228_K	0.564	1.00
387_I	446_Y	0.561	1.00
256_V	259_S	0.560	1.00
391_M	396_T	0.560	1.00
308_V	386_I	0.557	1.00
107_T	111_G	0.557	1.00
223_Y	227_R	0.554	1.00
22_M	334_L	0.554	1.00
403_I	444_L	0.554	1.00
275_F	279_Y	0.552	1.00
141_N	145_I	0.551	1.00
84_I	99_V	0.550	1.00
417_F	422_Y	0.550	1.00
204_G	208_A	0.549	1.00
61_S	139_S	0.549	1.00
18_V	330_V	0.548	1.00
63_F	67_F	0.548	1.00
289_V	363_T	0.546	1.00
275_F	430_V	0.545	1.00
57_A	60_S	0.545	1.00
161_T	164_R	0.545	1.00
115_A	147_F	0.543	1.00
156_Y	160_T	0.543	1.00
152_F	210_V	0.543	1.00
18_V	327_V	0.542	1.00
268_S	408_I	0.541	1.00
47_V	51_L	0.540	1.00
53_V	285_A	0.539	1.00
184_I	188_P	0.539	1.00
119_S	122_T	0.539	1.00
343_I	379_L	0.538	1.00
117_I	120_I	0.534	1.00
49_R	358_L	0.533	1.00
404_S	407_A	0.533	1.00
346_I	353_I	0.532	1.00
78_S	306_I	0.530	1.00
294_A	374_T	0.529	1.00
415_V	418_V	0.528	1.00
112_V	115_A	0.528	1.00
387_I	442_L	0.524	0.99
135_V	139_S	0.524	0.99
131_T	136_I	0.524	0.99
280_G	283_A	0.524	0.99
111_G	115_A	0.523	0.99
94_E	240_Y	0.523	0.99
119_S	147_F	0.522	0.99
164_R	169_S	0.521	0.99
415_V	433_G	0.521	0.99
69_L	150_M	0.521	0.99
282_N	285_A	0.520	0.99
163_L	223_Y	0.520	0.99
22_M	26_L	0.520	0.99
42_V	45_M	0.518	0.99
407_A	444_L	0.518	0.99
248_L	252_L	0.518	0.99
18_V	326_Q	0.518	0.99
208_A	212_S	0.516	0.99
351_H	372_M	0.516	0.99
328_I	332_I	0.516	0.99
76_I	110_L	0.516	0.99
190_L	207_Y	0.516	0.99
415_V	440_V	0.516	0.99
384_A	441_S	0.516	0.99
383_N	446_Y	0.514	0.99
332_I	387_I	0.514	0.99
45_M	357_F	0.514	0.99
19_W	326_Q	0.514	0.99
360_E	363_T	0.513	0.99
38_V	41_L	0.513	0.99
301_A	382_G	0.512	0.99
311_F	315_S	0.511	0.99
40_Q	146_L	0.511	0.99
84_I	100_V	0.511	0.99
295_S	298_Q	0.510	0.99
135_V	281_S	0.507	0.99
426_E	433_G	0.505	0.99
227_R	230_P	0.505	0.99
108_F	111_G	0.505	0.99
271_A	417_F	0.504	0.99
189_V	199_K	0.504	0.99
91_K	318_A	0.503	0.99
336_Y	339_G	0.501	0.99
309_S	389_A	0.501	0.99
234_D	240_Y	0.500	0.99
329_R	449_Y	0.500	0.99
51_L	191_I	0.500	0.99
112_V	151_P	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3mktA	1	0.9762	100	0.278	Contact Map
4humA	1	0.9827	100	0.279	Contact Map
4lz6A	1	0.9611	100	0.296	Contact Map
3w4tA	1	0.9546	100	0.353	Contact Map
4ikvA	1	0.892	74.5	0.944	Contact Map
4xnjA	1	0.8575	71.4	0.945	Contact Map
3wdoA	1	0.8445	62.6	0.948	Contact Map
1pw4A	1	0.8834	60.2	0.949	Contact Map
2cfqA	1	0.8639	54.1	0.951	Contact Map
3o7qA	1	0.8359	51.5	0.952	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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