GREMLIN Database
YLBP - Uncharacterized N-acetyltransferase YlbP
UniProt: O34468 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 160 (150)
Sequences: 122 (70)
Seq/√Len: 5.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
33_E61_S3.8400.91
115_P144_L3.6900.89
21_K31_L3.0540.77
80_L107_F2.5390.62
35_Q107_F2.5330.62
6_R125_K2.4340.59
43_S82_L2.2180.52
65_V139_K2.1780.50
75_N150_M2.1690.50
69_S147_H1.9420.42
57_V82_L1.8860.40
42_D78_D1.8090.38
39_I82_L1.7980.37
79_Y150_M1.7560.36
72_Y140_G1.7330.35
21_K102_E1.7270.35
57_V121_E1.7150.35
19_K55_K1.6920.34
102_E134_D1.6280.32
32_E81_E1.6270.32
91_Y107_F1.5840.31
39_I129_K1.5800.31
137_R143_P1.5490.30
115_P126_M1.5020.28
29_S101_V1.4990.28
14_L38_I1.4980.28
99_A121_E1.4860.28
103_F107_F1.4700.27
42_D69_S1.4430.27
58_A100_L1.4420.27
18_K135_M1.4090.26
52_F96_Y1.3970.25
114_N142_N1.3900.25
112_R150_M1.3580.24
95_G103_F1.3570.24
19_K31_L1.3510.24
33_E38_I1.3500.24
115_P139_K1.3380.24
140_G143_P1.3290.24
34_L45_S1.3290.24
44_T132_K1.3280.24
39_I43_S1.3240.24
58_A96_Y1.3020.23
133_Y137_R1.3010.23
25_I130_T1.2970.23
139_K144_L1.2650.22
9_I132_K1.2510.22
125_K130_T1.2260.21
83_W140_G1.2250.21
41_N44_T1.2220.21
53_G105_K1.2200.21
23_Y26_Q1.2190.21
14_L57_V1.1970.21
98_R126_M1.1950.21
36_D55_K1.1890.20
64_Q78_D1.1810.20
95_G109_M1.1690.20
118_K144_L1.1680.20
29_S81_E1.1650.20
72_Y131_V1.1590.20
115_P135_M1.1550.20
70_N75_N1.1490.20
5_E58_A1.1470.19
74_D106_S1.1420.19
64_Q109_M1.1390.19
53_G60_M1.1360.19
114_N143_P1.1280.19
37_N124_N1.1270.19
42_D82_L1.1150.19
33_E42_D1.1070.19
107_F144_L1.0980.18
78_D141_E1.0810.18
3_K19_K1.0810.18
93_N129_K1.0800.18
99_A125_K1.0680.18
44_T123_W1.0640.18
9_I108_K1.0630.18
96_Y147_H1.0600.18
31_L117_M1.0370.17
3_K94_R1.0370.17
18_K31_L1.0330.17
83_W143_P1.0310.17
40_E113_T1.0210.17
5_E89_P1.0060.17
52_F94_R0.9930.16
133_Y143_P0.9880.16
108_K152_R0.9880.16
18_K118_K0.9800.16
77_Q151_D0.9790.16
92_Q95_G0.9690.16
83_W137_R0.9640.16
39_I91_Y0.9640.16
22_E118_K0.9550.16
138_D143_P0.9410.15
26_Q142_N0.9350.15
98_R102_E0.9330.15
115_P119_S0.9220.15
93_N132_K0.9180.15
11_Y58_A0.9080.15
92_Q103_F0.9080.15
92_Q118_K0.9070.15
6_R39_I0.9030.15
16_E61_S0.9010.15
114_N137_R0.8900.14
33_E89_P0.8860.14
42_D102_E0.8800.14
42_D57_V0.8790.14
22_E91_Y0.8730.14
89_P96_Y0.8700.14
18_K136_A0.8690.14
25_I134_D0.8610.14
38_I108_K0.8590.14
136_A150_M0.8570.14
9_I38_I0.8500.14
41_N113_T0.8470.14
25_I147_H0.8460.14
9_I76_R0.8440.14
120_A145_I0.8330.14
8_L35_Q0.8310.14
18_K92_Q0.8310.14
75_N145_I0.8300.13
63_Y81_E0.8280.13
19_K136_A0.8270.13
54_D99_A0.8270.13
22_E80_L0.8270.13
131_V145_I0.8160.13
11_Y96_Y0.8140.13
75_N114_N0.8120.13
137_R142_N0.8080.13
129_K147_H0.8070.13
70_N77_Q0.7970.13
16_E81_E0.7920.13
111_I117_M0.7910.13
14_L61_S0.7900.13
80_L108_K0.7830.13
25_I121_E0.7830.13
24_G56_L0.7710.13
29_S123_W0.7690.13
53_G119_S0.7630.12
5_E66_N0.7610.12
9_I91_Y0.7470.12
43_S101_V0.7460.12
44_T102_E0.7460.12
64_Q71_P0.7440.12
101_V113_T0.7380.12
26_Q135_M0.7320.12
78_D106_S0.7270.12
14_L82_L0.7240.12
51_Y63_Y0.7240.12
66_N147_H0.7190.12
48_Y55_K0.7140.12
8_L131_V0.7130.12
54_D126_M0.7130.12
70_N151_D0.7130.12
29_S113_T0.7130.12
36_D103_F0.7110.12
43_S140_G0.7110.12
121_E124_N0.7090.12
19_K36_D0.7090.12
111_I115_P0.7060.12
31_L89_P0.7050.12
75_N143_P0.7050.12
113_T123_W0.7030.12
18_K115_P0.7020.12
6_R42_D0.6920.11
81_E113_T0.6880.11
63_Y97_G0.6830.11
69_S130_T0.6820.11
81_E101_V0.6800.11
75_N151_D0.6740.11
25_I36_D0.6720.11
35_Q91_Y0.6640.11
54_D93_N0.6630.11
33_E127_N0.6610.11
26_Q119_S0.6490.11
51_Y81_E0.6480.11
83_W138_D0.6480.11
50_I103_F0.6380.11
71_P139_K0.6310.11
35_Q82_L0.6290.11
117_M120_A0.6200.10
44_T103_F0.6180.10
21_K108_K0.6160.10
117_M129_K0.6160.10
11_Y132_K0.6130.10
135_M144_L0.6090.10
8_L135_M0.6070.10
89_P101_V0.5990.10
14_L27_E0.5970.10
44_T129_K0.5970.10
111_I118_K0.5920.10
11_Y50_I0.5920.10
96_Y144_L0.5810.10
103_F124_N0.5790.10
92_Q144_L0.5760.10
9_I79_Y0.5750.10
41_N123_W0.5710.10
102_E131_V0.5700.10
18_K111_I0.5670.10
102_E108_K0.5660.10
31_L65_V0.5640.10
65_V76_R0.5620.10
22_E101_V0.5610.10
74_D109_M0.5600.10
8_L36_D0.5540.10
6_R82_L0.5540.10
121_E129_K0.5540.10
37_N101_V0.5410.09
80_L126_M0.5400.09
90_G108_K0.5400.09
55_K130_T0.5390.09
121_E130_T0.5360.09
72_Y83_W0.5340.09
18_K117_M0.5320.09
52_F64_Q0.5310.09
106_S121_E0.5250.09
133_Y138_D0.5230.09
32_E98_R0.5200.09
129_K132_K0.5190.09
35_Q89_P0.5180.09
69_S75_N0.5180.09
83_W133_Y0.5170.09
31_L102_E0.5130.09
102_E129_K0.5120.09
41_N52_F0.5000.09
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2pr1A 3 0.95 99.8 0.751 Contact Map
2jdcA 1 0.8688 98.4 0.883 Contact Map
1q2yA 1 0.8313 98.4 0.883 Contact Map
2q0yA 2 0.8375 98.4 0.884 Contact Map
3i3gA 2 0.8187 98.3 0.885 Contact Map
2atrA 2 0.7688 98.3 0.885 Contact Map
1ufhA 3 0.7875 98.3 0.885 Contact Map
3exnA 1 0.8438 98.3 0.886 Contact Map
3t9yA 2 0.7625 98.3 0.886 Contact Map
1y7rA 2 0.7812 98.3 0.887 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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