GREMLIN Database
YTRI - Sporulation membrane protein YtrI
UniProt: O34460 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 167 (164)
Sequences: 109 (97)
Seq/√Len: 7.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
31_L84_V3.1630.89
129_K150_E2.9710.85
149_R162_E2.7270.80
110_I113_V2.4440.72
113_V157_L2.4160.71
2_R27_W2.2740.66
23_A26_S2.2670.66
65_D74_K2.2520.65
19_M34_Y2.2200.64
37_F163_I2.2110.64
29_F90_D2.1530.61
74_K128_L2.0690.58
15_F135_K2.0440.57
118_I154_Y2.0320.57
2_R154_Y2.0070.56
32_F36_T1.9000.51
6_H94_I1.8840.51
51_H56_N1.8630.50
92_Y115_T1.8590.50
129_K148_V1.8240.48
55_L75_R1.8010.48
147_T164_S1.7830.47
1_M4_P1.7670.46
6_H11_G1.7510.46
109_D128_L1.7230.44
78_L82_V1.6830.43
27_W45_I1.6540.42
2_R45_I1.6400.41
52_V148_V1.6390.41
79_I118_I1.6190.40
33_T163_I1.6090.40
121_V146_A1.6060.40
33_T98_D1.6040.40
113_V128_L1.5920.39
147_T162_E1.5890.39
77_L101_K1.5590.38
24_V146_A1.5350.37
79_I151_L1.5100.36
122_Y129_K1.5060.36
16_F144_Y1.5040.36
5_Q13_Q1.5030.36
30_F121_V1.4950.36
87_L126_D1.4840.35
94_I99_K1.4620.34
70_N77_L1.4550.34
38_Q41_Q1.4270.33
132_I157_L1.4190.33
7_Y13_Q1.4070.33
48_Q52_V1.4060.33
45_I48_Q1.3900.32
40_E157_L1.3880.32
45_I49_K1.3840.32
32_F95_S1.3680.31
48_Q70_N1.3670.31
26_S29_F1.3590.31
62_Y66_L1.3540.31
44_L102_F1.3490.31
25_I149_R1.3460.30
142_K153_I1.3340.30
74_K118_I1.3330.30
107_K161_L1.3320.30
44_L148_V1.3250.30
3_V7_Y1.3180.29
5_Q161_L1.2560.27
19_M29_F1.2250.26
2_R142_K1.2100.26
70_N80_Q1.2050.26
25_I83_S1.1880.25
17_A30_F1.1870.25
47_K86_L1.1800.25
93_K110_I1.1720.25
153_I164_S1.1650.25
142_K150_E1.1500.24
93_K124_T1.1390.24
57_N77_L1.1320.24
62_Y115_T1.1150.23
16_F106_V1.1000.23
73_N126_D1.0910.23
90_D143_K1.0860.22
86_L92_Y1.0780.22
2_R155_T1.0560.22
100_T115_T1.0400.21
79_I153_I1.0260.21
27_W134_N1.0140.20
15_F78_L1.0120.20
26_S122_Y1.0040.20
39_E113_V0.9940.20
16_F97_P0.9800.20
2_R48_Q0.9760.19
72_D113_V0.9720.19
48_Q155_T0.9580.19
64_E114_I0.9580.19
8_K12_W0.9380.19
73_N80_Q0.9220.18
60_S102_F0.9210.18
51_H83_S0.9090.18
92_Y140_N0.9020.18
111_S160_E0.9000.18
31_L120_S0.8980.18
138_M141_E0.8940.18
52_V55_L0.8850.17
20_M78_L0.8850.17
45_I156_R0.8820.17
84_V159_V0.8760.17
40_E111_S0.8660.17
79_I82_V0.8630.17
16_F146_A0.8630.17
29_F104_E0.8610.17
81_S100_T0.8600.17
117_D131_T0.8600.17
33_T104_E0.8580.17
107_K110_I0.8510.17
122_Y125_K0.8440.16
27_W142_K0.8430.16
144_Y153_I0.8400.16
49_K148_V0.8390.16
39_E60_S0.8380.16
25_I84_V0.8330.16
38_Q109_D0.8320.16
119_E139_I0.8280.16
74_K112_E0.8260.16
68_K79_I0.8230.16
88_N134_N0.8180.16
28_F148_V0.8180.16
28_F59_I0.8170.16
54_D132_I0.8150.16
93_K157_L0.8130.16
86_L160_E0.8110.16
18_G27_W0.8060.16
104_E141_E0.8000.15
120_S154_Y0.7970.15
110_I123_Q0.7950.15
42_V61_I0.7940.15
41_Q44_L0.7920.15
86_L157_L0.7900.15
112_E128_L0.7860.15
31_L157_L0.7800.15
72_D118_I0.7800.15
27_W48_Q0.7690.15
79_I157_L0.7660.15
72_D131_T0.7640.15
125_K150_E0.7640.15
51_H75_R0.7610.15
34_Y100_T0.7570.15
27_W30_F0.7550.15
16_F82_V0.7530.14
20_M67_H0.7380.14
116_K163_I0.7340.14
18_G133_E0.7300.14
78_L146_A0.7280.14
44_L49_K0.7280.14
37_F146_A0.7260.14
31_L113_V0.7220.14
52_V132_I0.7200.14
110_I157_L0.7190.14
1_M22_G0.7150.14
13_Q42_V0.7100.14
28_F94_I0.7080.14
76_K94_I0.7060.14
47_K125_K0.7050.14
141_E151_L0.6890.13
73_N155_T0.6870.13
64_E68_K0.6860.13
18_G22_G0.6830.13
120_S123_Q0.6830.13
6_H87_L0.6800.13
37_F41_Q0.6760.13
32_F128_L0.6740.13
79_I162_E0.6680.13
47_K140_N0.6670.13
108_D114_I0.6630.13
69_L88_N0.6620.13
15_F18_G0.6570.13
2_R115_T0.6530.13
76_K162_E0.6520.13
7_Y161_L0.6510.13
126_D140_N0.6460.12
84_V120_S0.6420.12
34_Y63_Q0.6350.12
11_G100_T0.6340.12
54_D104_E0.6320.12
125_K140_N0.6310.12
48_Q150_E0.6270.12
113_V153_I0.6260.12
138_M151_L0.6250.12
60_S63_Q0.6230.12
14_R134_N0.6220.12
75_R104_E0.6110.12
3_V52_V0.6060.12
19_M107_K0.6030.12
50_E62_Y0.5990.12
8_K102_F0.5990.12
26_S30_F0.5950.12
55_L58_Q0.5920.12
25_I28_F0.5900.12
39_E116_K0.5900.12
49_K106_V0.5900.12
80_Q157_L0.5890.12
6_H25_I0.5790.11
52_V77_L0.5750.11
99_K110_I0.5730.11
19_M130_R0.5680.11
59_I147_T0.5660.11
9_K97_P0.5640.11
44_L109_D0.5630.11
80_Q129_K0.5630.11
125_K158_T0.5620.11
131_T160_E0.5590.11
136_V141_E0.5580.11
20_M55_L0.5570.11
26_S85_K0.5560.11
26_S86_L0.5560.11
57_N84_V0.5540.11
53_K56_N0.5530.11
42_V152_I0.5510.11
45_I102_F0.5510.11
53_K84_V0.5490.11
1_M12_W0.5480.11
91_K128_L0.5460.11
33_T60_S0.5440.11
4_P22_G0.5410.11
48_Q142_K0.5390.11
12_W159_V0.5380.11
27_W113_V0.5360.11
81_S156_R0.5350.11
19_M26_S0.5330.11
5_Q10_P0.5320.11
9_K114_I0.5300.11
74_K144_Y0.5290.11
27_W105_H0.5290.11
111_S122_Y0.5270.11
105_H163_I0.5210.10
7_Y108_D0.5180.10
20_M58_Q0.5150.10
90_D96_Q0.5140.10
116_K142_K0.5110.10
76_K119_E0.5090.10
83_S106_V0.5090.10
74_K110_I0.5070.10
58_Q81_S0.5070.10
154_Y160_E0.5060.10
32_F98_D0.5060.10
6_H127_L0.5040.10
107_K151_L0.5040.10
27_W155_T0.5030.10
62_Y86_L0.5000.10
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3wuqA 1 0.521 51.8 0.945 Contact Map
3rvyA 3 0.2275 51.8 0.945 Contact Map
2uygA 4 0.2515 49.7 0.946 Contact Map
3effK 4 0.3952 45.3 0.947 Contact Map
3qnqA 2 0.3114 34.4 0.951 Contact Map
3pjsK 4 0.3952 32.8 0.951 Contact Map
4bgnA 3 0.2515 26 0.954 Contact Map
4rh7A 1 0.9281 19.2 0.957 Contact Map
2l5gB 1 0.2515 16.3 0.958 Contact Map
4n0aH 1 0.497 14.8 0.959 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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