YFKH - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YFKH - Putative ribonuclease-like protein YfkH

UniProt:	O34437	Sequences: MSFLKELFSRYTLHEGQSKSAELAYFFLLSLFPFLIFMLTLTAYLPLSTDDVLGVIEQYAPASAMSLVESITHQTLNNRNGGLLSFGIIAALWSASNGMNAIVRSLNHAYDVEENRSFIIVRLTSIFLTIAMVFTILVALLLPVFGREIGRLASDFVGASDLFLSVWAAIRWGVSPLVLLIVFSALYVIAPNKKLSLRFVMPGAVFATIGWIIVSTLFSFYVSTFANYSATYGSIGGIIVLMIWFYLSGILIILGGEINALLHKRKKLPDENPYH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	275 (261)
Sequences:	5339 (3909)
Seq/√Len:	241.9

ECOLI - YHJD YIHY
BACSU - YFKH

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
14_H	257_E	5.900	1.00
15_E	108_H	3.934	1.00
211_W	248_S	3.273	1.00
17_Q	250_I	3.199	1.00
203_G	259_N	3.043	1.00
214_V	247_L	2.999	1.00
206_F	258_I	2.926	1.00
106_L	256_G	2.883	1.00
123_L	127_F	2.817	1.00
21_A	26_F	2.803	1.00
18_S	22_E	2.652	1.00
100_N	122_R	2.554	1.00
63_S	66_S	2.546	1.00
11_Y	16_G	2.498	1.00
184_S	204_A	2.460	1.00
184_S	197_L	2.442	1.00
7_L	254_L	2.418	1.00
206_F	210_G	2.348	1.00
11_Y	250_I	2.181	1.00
117_S	120_I	2.079	1.00
187_Y	207_A	2.012	1.00
15_E	104_R	2.004	1.00
14_H	111_D	1.978	1.00
106_L	190_A	1.968	1.00
56_I	60_A	1.947	1.00
180_L	205_V	1.918	1.00
107_N	191_P	1.907	1.00
180_L	201_M	1.894	1.00
200_V	204_A	1.889	1.00
187_Y	255_G	1.883	1.00
7_L	258_I	1.872	1.00
23_L	249_G	1.833	1.00
6_E	265_R	1.823	1.00
218_F	222_V	1.822	1.00
202_P	259_N	1.816	1.00
110_Y	259_N	1.804	1.00
105_S	253_I	1.779	1.00
107_N	192_N	1.771	1.00
188_V	197_L	1.719	1.00
207_A	255_G	1.682	1.00
51_D	54_G	1.664	1.00
10_R	14_H	1.654	1.00
96_S	122_R	1.647	1.00
217_L	220_F	1.632	1.00
220_F	224_T	1.630	1.00
119_I	123_L	1.618	1.00
73_H	77_N	1.596	1.00
103_V	125_S	1.577	1.00
115_N	192_N	1.576	1.00
212_I	215_S	1.574	1.00
66_S	69_E	1.572	1.00
180_L	208_T	1.567	1.00
10_R	111_D	1.567	1.00
222_V	240_V	1.551	1.00
30_S	98_G	1.550	1.00
6_E	261_L	1.539	1.00
122_R	125_S	1.513	1.00
85_S	89_I	1.511	1.00
7_L	261_L	1.503	1.00
165_S	169_A	1.482	1.00
8_F	12_T	1.463	1.00
89_I	93_W	1.450	1.00
5_K	9_S	1.444	1.00
195_L	200_V	1.440	1.00
183_F	252_I	1.440	1.00
10_R	257_E	1.439	1.00
15_E	18_S	1.432	1.00
70_S	73_H	1.419	1.00
10_R	261_L	1.417	1.00
184_S	200_V	1.408	1.00
109_A	253_I	1.399	1.00
20_S	250_I	1.398	1.00
7_L	16_G	1.383	1.00
126_I	130_I	1.376	1.00
107_N	112_V	1.364	1.00
176_P	208_T	1.361	1.00
69_E	73_H	1.358	1.00
66_S	70_S	1.358	1.00
103_V	190_A	1.353	1.00
20_S	253_I	1.347	1.00
9_S	13_L	1.325	1.00
210_G	251_L	1.317	1.00
196_S	199_F	1.312	1.00
209_I	213_I	1.282	1.00
116_R	124_T	1.279	1.00
199_F	263_H	1.279	1.00
10_R	260_A	1.275	1.00
183_F	208_T	1.257	1.00
26_F	30_S	1.255	1.00
199_F	262_L	1.253	1.00
201_M	205_V	1.250	1.00
215_S	244_W	1.249	1.00
53_L	65_M	1.230	1.00
180_L	184_S	1.224	1.00
23_L	253_I	1.221	1.00
86_F	90_A	1.216	1.00
118_F	122_R	1.189	1.00
188_V	200_V	1.180	1.00
23_L	105_S	1.178	1.00
64_A	67_L	1.170	1.00
202_P	206_F	1.142	1.00
57_E	65_M	1.134	1.00
18_S	104_R	1.133	1.00
162_L	166_V	1.128	1.00
62_A	66_S	1.127	1.00
180_L	204_A	1.110	1.00
4_L	7_L	1.110	1.00
228_Y	232_Y	1.106	1.00
186_L	190_A	1.090	1.00
202_P	205_V	1.073	1.00
50_D	54_G	1.072	1.00
24_A	249_G	1.062	1.00
195_L	199_F	1.059	1.00
258_I	262_L	1.058	1.00
27_F	245_F	1.052	1.00
37_F	84_L	1.045	1.00
11_Y	254_L	1.040	1.00
234_S	237_G	1.030	1.00
109_A	257_E	1.029	1.00
185_A	189_I	1.023	1.00
201_M	204_A	1.017	1.00
16_G	250_I	1.011	1.00
25_Y	243_I	1.008	1.00
68_V	71_I	1.005	1.00
19_K	105_S	1.000	1.00
25_Y	242_M	0.998	1.00
120_I	124_T	0.998	1.00
16_G	254_L	0.994	1.00
95_A	129_T	0.988	1.00
53_L	69_E	0.988	1.00
184_S	188_V	0.987	1.00
236_G	240_V	0.978	1.00
9_S	12_T	0.977	1.00
26_F	94_S	0.976	1.00
110_Y	215_S	0.974	1.00
15_E	19_K	0.970	1.00
16_G	257_E	0.967	1.00
46_P	50_D	0.963	1.00
55_V	58_Q	0.962	1.00
19_K	22_E	0.954	1.00
112_V	192_N	0.953	1.00
187_Y	256_G	0.950	1.00
19_K	108_H	0.949	1.00
29_L	239_I	0.947	1.00
79_R	82_G	0.938	1.00
99_M	103_V	0.935	1.00
10_R	264_K	0.933	1.00
261_L	264_K	0.930	1.00
140_L	144_V	0.928	1.00
71_I	75_T	0.924	1.00
23_L	102_I	0.924	1.00
244_W	248_S	0.921	1.00
183_F	207_A	0.919	1.00
76_L	79_R	0.917	1.00
49_T	52_V	0.915	1.00
151_R	155_D	0.914	1.00
74_Q	77_N	0.914	1.00
21_A	246_Y	0.913	1.00
4_L	8_F	0.911	1.00
150_G	154_S	0.908	1.00
26_F	101_A	0.907	1.00
221_Y	225_F	0.906	1.00
254_L	258_I	0.905	1.00
71_I	74_Q	0.899	1.00
208_T	212_I	0.898	1.00
18_S	101_A	0.895	1.00
204_A	208_T	0.895	1.00
176_P	180_L	0.894	1.00
84_L	88_I	0.891	1.00
24_A	245_F	0.890	1.00
245_F	249_G	0.889	1.00
183_F	211_W	0.885	1.00
36_I	40_T	0.883	0.99
218_F	240_V	0.880	0.99
40_T	87_G	0.877	0.99
241_L	244_W	0.872	0.99
218_F	241_L	0.872	0.99
19_K	25_Y	0.863	0.99
54_G	57_E	0.862	0.99
37_F	87_G	0.858	0.99
24_A	246_Y	0.858	0.99
206_F	255_G	0.853	0.99
231_T	234_S	0.849	0.99
62_A	65_M	0.842	0.99
29_L	243_I	0.841	0.99
188_V	194_K	0.840	0.99
101_A	104_R	0.838	0.99
218_F	228_Y	0.836	0.99
154_S	158_G	0.835	0.99
166_V	169_A	0.828	0.99
214_V	248_S	0.825	0.99
11_Y	17_Q	0.824	0.99
55_V	59_Y	0.824	0.99
227_N	230_A	0.820	0.99
96_S	129_T	0.818	0.99
152_L	156_F	0.815	0.99
120_I	123_L	0.807	0.99
229_S	233_G	0.802	0.99
22_E	101_A	0.799	0.99
51_D	55_V	0.799	0.99
87_G	90_A	0.798	0.99
225_F	228_Y	0.795	0.99
213_I	217_L	0.792	0.99
32_F	238_I	0.789	0.99
12_T	17_Q	0.785	0.99
217_L	247_L	0.783	0.99
184_S	201_M	0.778	0.99
177_L	180_L	0.772	0.99
27_F	249_G	0.770	0.99
53_L	57_E	0.769	0.99
17_Q	20_S	0.768	0.99
169_A	173_G	0.768	0.99
202_P	262_L	0.767	0.99
16_G	253_I	0.759	0.98
147_R	151_R	0.757	0.98
97_N	122_R	0.757	0.98
24_A	28_L	0.753	0.98
25_Y	29_L	0.751	0.98
21_A	25_Y	0.749	0.98
24_A	242_M	0.748	0.98
100_N	104_R	0.745	0.98
224_T	227_N	0.744	0.98
160_S	163_F	0.743	0.98
34_F	129_T	0.740	0.98
211_W	234_S	0.738	0.98
56_I	65_M	0.738	0.98
57_E	69_E	0.734	0.98
193_K	263_H	0.733	0.98
98_G	249_G	0.731	0.98
70_S	74_Q	0.728	0.98
163_F	167_W	0.721	0.98
159_A	162_L	0.719	0.98
124_T	127_F	0.710	0.98
71_I	76_L	0.709	0.98
198_R	201_M	0.701	0.97
38_M	41_L	0.701	0.97
94_S	101_A	0.698	0.97
143_P	212_I	0.694	0.97
114_E	121_V	0.693	0.97
137_L	140_L	0.692	0.97
60_A	65_M	0.690	0.97
103_V	121_V	0.689	0.97
177_L	181_I	0.688	0.97
71_I	90_A	0.687	0.97
96_S	125_S	0.686	0.97
79_R	83_L	0.684	0.97
13_L	113_E	0.682	0.97
32_F	61_P	0.680	0.97
246_Y	251_L	0.675	0.97
36_I	87_G	0.674	0.97
112_V	193_K	0.674	0.97
170_I	173_G	0.672	0.97
261_L	265_R	0.671	0.97
32_F	239_I	0.671	0.97
147_R	150_G	0.670	0.97
131_A	236_G	0.669	0.97
200_V	259_N	0.665	0.96
153_A	157_V	0.660	0.96
186_L	252_I	0.660	0.96
206_F	209_I	0.660	0.96
212_I	216_T	0.658	0.96
254_L	257_E	0.657	0.96
143_P	215_S	0.657	0.96
179_L	208_T	0.656	0.96
33_P	233_G	0.653	0.96
23_L	30_S	0.653	0.96
103_V	122_R	0.649	0.96
86_F	148_E	0.648	0.96
114_E	192_N	0.646	0.96
87_G	250_I	0.645	0.96
99_M	128_L	0.643	0.96
54_G	155_D	0.641	0.96
17_Q	246_Y	0.638	0.96
7_L	11_Y	0.634	0.95
211_W	245_F	0.630	0.95
94_S	97_N	0.629	0.95
135_T	139_A	0.625	0.95
102_I	130_I	0.624	0.95
179_L	215_S	0.624	0.95
207_A	251_L	0.624	0.95
31_L	210_G	0.622	0.95
143_P	172_W	0.620	0.95
21_A	24_A	0.620	0.95
210_G	214_V	0.619	0.95
106_L	252_I	0.613	0.95
216_T	220_F	0.613	0.95
203_G	207_A	0.609	0.94
22_E	100_N	0.609	0.94
214_V	251_L	0.609	0.94
100_N	125_S	0.608	0.94
35_L	150_G	0.606	0.94
89_I	223_S	0.604	0.94
60_A	68_V	0.604	0.94
117_S	122_R	0.603	0.94
260_A	264_K	0.601	0.94
234_S	238_I	0.601	0.94
107_N	116_R	0.595	0.94
30_S	81_G	0.594	0.94
72_T	101_A	0.593	0.93
154_S	159_A	0.592	0.93
185_A	188_V	0.591	0.93
156_F	160_S	0.589	0.93
35_L	72_T	0.587	0.93
72_T	76_L	0.586	0.93
54_G	58_Q	0.585	0.93
14_H	246_Y	0.585	0.93
33_P	92_L	0.583	0.93
226_A	240_V	0.582	0.93
139_A	178_V	0.582	0.93
37_F	133_V	0.580	0.93
203_G	206_F	0.579	0.93
49_T	53_L	0.579	0.93
152_L	157_V	0.579	0.93
93_W	251_L	0.577	0.93
195_L	263_H	0.576	0.92
221_Y	226_A	0.574	0.92
121_V	136_I	0.574	0.92
100_N	103_V	0.572	0.92
146_G	167_W	0.572	0.92
4_L	151_R	0.571	0.92
48_S	51_D	0.569	0.92
69_E	72_T	0.568	0.92
177_L	196_S	0.568	0.92
27_F	37_F	0.568	0.92
26_F	93_W	0.567	0.92
128_L	190_A	0.567	0.92
85_S	92_L	0.564	0.92
183_F	200_V	0.564	0.92
138_V	141_L	0.562	0.92
110_Y	260_A	0.560	0.91
111_D	138_V	0.560	0.91
30_S	95_A	0.560	0.91
92_L	138_V	0.557	0.91
93_W	96_S	0.554	0.91
173_G	177_L	0.552	0.91
29_L	67_L	0.552	0.91
34_F	143_P	0.549	0.91
164_L	168_A	0.548	0.91
54_G	66_S	0.548	0.91
28_L	242_M	0.545	0.90
220_F	223_S	0.545	0.90
110_Y	191_P	0.544	0.90
134_F	138_V	0.544	0.90
218_F	221_Y	0.542	0.90
253_I	257_E	0.542	0.90
31_L	90_A	0.541	0.90
105_S	257_E	0.537	0.90
25_Y	97_N	0.537	0.90
93_W	202_P	0.536	0.90
189_I	197_L	0.534	0.89
25_Y	28_L	0.534	0.89
96_S	100_N	0.532	0.89
24_A	235_I	0.531	0.89
7_L	10_R	0.531	0.89
50_D	69_E	0.530	0.89
99_M	183_F	0.528	0.89
138_V	165_S	0.527	0.89
153_A	156_F	0.526	0.89
104_R	108_H	0.526	0.89
25_Y	252_I	0.525	0.89
211_W	215_S	0.523	0.88
159_A	165_S	0.523	0.88
111_D	114_E	0.517	0.88
102_I	253_I	0.517	0.88
187_Y	204_A	0.517	0.88
163_F	170_I	0.515	0.88
103_V	243_I	0.514	0.88
252_I	255_G	0.513	0.87
30_S	252_I	0.511	0.87
14_H	261_L	0.511	0.87
98_G	101_A	0.511	0.87
5_K	12_T	0.510	0.87
151_R	154_S	0.510	0.87
90_A	201_M	0.509	0.87
37_F	91_A	0.509	0.87
106_L	112_V	0.508	0.87
103_V	239_I	0.508	0.87
145_F	234_S	0.507	0.87
37_F	99_M	0.506	0.87
60_A	72_T	0.506	0.87
169_A	174_V	0.506	0.87
22_E	246_Y	0.506	0.87
176_P	212_I	0.504	0.87
213_I	216_T	0.504	0.87
100_N	121_V	0.504	0.87
179_L	212_I	0.504	0.87
29_L	94_S	0.502	0.86
235_I	239_I	0.502	0.86
145_F	148_E	0.502	0.86
29_L	225_F	0.501	0.86
96_S	235_I	0.501	0.86
165_S	168_A	0.500	0.86

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3rlfF	1	0.44	38.8	0.936	Contact Map
3dh4A	3	0.8582	11.1	0.951	Contact Map
3j9pD	4	0.7782	7.3	0.954	Contact Map
4gx0A	3	0.3818	6.9	0.955	Contact Map
2k1eA	3	0.3709	6.6	0.955	Contact Map
3effK	4	0.3927	6.3	0.956	Contact Map
4od4A	1	0.6582	5.8	0.956	Contact Map
2kluA	1	0.1636	5.4	0.957	Contact Map
2xq2A	2	0.8436	5	0.958	Contact Map
4humA	1	0.8145	4.5	0.959	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0091 seconds.