YJLA - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YJLA - Uncharacterized protein YjlA

UniProt:	O34428	Sequences: MKAIVIGILASLFFAVTFILNRAMELSGGSWLWSSSLRFIFMVPFLCLIVIMRGTFTPLLLEMRKKPFYWIKWSFVGFVLFYAPITFAAAYGPGWLIAGTWQITIVAGVLLSPLFYVKQDMPGGPQLIRQKIPLVSLGTSVIILIGAALIQLQHAESLSGRMLLFSVLPVVIAAFAYPLGNRRMLEEYGGRLDTFQRVLGMTLASLPFWLILAAYGWWSDGLPTASQTVQSFIVAVSSGIIATVLFFWATDMVRDNPQKLAAVEATQSGEVIFALLGEIVLLSGVFPSLLSFAGLFIIIAGMMLHTFASQPRKPKKKAQSNLTA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	324 (300)
Sequences:	287 (223)
Seq/√Len:	12.9

BACSU - YJLA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
75_F	79_V	4.943	1.00
53_R	193_D	4.123	1.00
32_L	216_G	4.070	1.00
109_V	112_S	3.991	1.00
150_I	298_I	3.794	0.99
107_A	174_A	3.737	0.99
74_S	204_A	3.586	0.99
92_G	166_S	3.506	0.99
59_L	63_M	3.418	0.99
11_S	269_G	3.316	0.98
12_L	16_V	3.038	0.97
22_R	26_L	2.963	0.96
62_E	191_R	2.767	0.94
168_L	172_I	2.632	0.93
275_L	295_L	2.457	0.90
94_G	284_G	2.453	0.90
10_A	285_V	2.403	0.89
63_M	204_A	2.363	0.88
278_E	284_G	2.287	0.86
3_A	107_A	2.204	0.84
270_E	274_A	2.166	0.83
16_V	237_S	2.162	0.83
80_L	84_P	2.124	0.82
43_V	206_L	2.122	0.82
233_I	237_S	2.087	0.80
139_T	308_A	2.035	0.79
35_S	282_L	2.019	0.78
7_G	18_F	2.005	0.78
156_E	232_F	1.990	0.77
269_G	274_A	1.922	0.74
11_S	92_G	1.899	0.74
89_A	274_A	1.801	0.69
209_W	234_V	1.788	0.69
23_A	26_L	1.751	0.67
56_F	60_L	1.738	0.67
69_Y	187_E	1.734	0.66
210_L	214_A	1.730	0.66
171_V	213_A	1.712	0.65
3_A	86_T	1.711	0.65
15_A	147_A	1.694	0.64
68_F	72_K	1.690	0.64
148_A	167_V	1.667	0.63
79_V	270_E	1.663	0.63
182_R	264_E	1.649	0.62
32_L	213_A	1.619	0.61
164_L	298_I	1.608	0.60
87_F	169_P	1.600	0.60
85_I	285_V	1.589	0.59
48_L	241_I	1.585	0.59
79_V	98_A	1.570	0.58
83_A	271_V	1.563	0.58
50_V	193_D	1.555	0.58
6_I	76_V	1.554	0.58
19_I	72_K	1.539	0.57
11_S	270_E	1.532	0.56
3_A	274_A	1.530	0.56
24_M	34_S	1.486	0.54
43_V	202_T	1.469	0.53
116_Y	129_R	1.468	0.53
12_L	86_T	1.456	0.52
79_V	208_F	1.447	0.52
98_A	136_S	1.436	0.51
105_I	278_E	1.415	0.50
86_T	255_D	1.408	0.50
108_G	182_R	1.402	0.50
108_G	264_E	1.402	0.50
166_S	170_V	1.388	0.49
218_W	279_I	1.371	0.48
198_V	244_V	1.369	0.48
3_A	269_G	1.367	0.48
193_D	278_E	1.347	0.47
39_F	242_A	1.341	0.46
3_A	244_V	1.339	0.46
215_Y	256_N	1.338	0.46
169_P	277_G	1.334	0.46
56_F	145_I	1.332	0.46
214_A	303_M	1.317	0.45
86_T	298_I	1.316	0.45
19_I	149_L	1.316	0.45
11_S	106_V	1.316	0.45
250_T	264_E	1.310	0.45
182_R	250_T	1.310	0.45
70_W	200_G	1.307	0.45
85_I	189_G	1.304	0.45
53_R	278_E	1.302	0.44
58_P	196_Q	1.294	0.44
15_A	251_D	1.292	0.44
254_R	285_V	1.289	0.44
85_I	195_F	1.289	0.44
161_R	222_L	1.286	0.44
93_P	262_A	1.279	0.43
140_S	305_H	1.271	0.43
6_I	212_L	1.263	0.42
143_I	201_M	1.259	0.42
20_L	34_S	1.253	0.42
74_S	253_V	1.251	0.42
35_S	215_Y	1.242	0.41
113_P	221_G	1.234	0.41
106_V	222_L	1.221	0.40
102_Q	133_P	1.220	0.40
111_L	151_Q	1.203	0.39
275_L	291_S	1.202	0.39
85_I	144_L	1.199	0.39
79_V	275_L	1.181	0.38
115_F	186_E	1.174	0.38
205_S	208_F	1.165	0.38
112_S	216_G	1.160	0.37
193_D	199_L	1.159	0.37
144_L	148_A	1.158	0.37
19_I	171_V	1.152	0.37
195_F	255_D	1.148	0.37
32_L	212_L	1.139	0.36
63_M	253_V	1.132	0.36
290_L	295_L	1.124	0.36
79_V	205_S	1.120	0.35
50_V	53_R	1.108	0.35
40_I	268_S	1.103	0.35
61_L	64_R	1.094	0.34
55_T	89_A	1.091	0.34
63_M	193_D	1.085	0.34
213_A	237_S	1.082	0.34
135_V	231_S	1.080	0.34
167_V	216_G	1.079	0.33
59_L	199_L	1.078	0.33
33_W	213_A	1.078	0.33
147_A	226_S	1.073	0.33
27_S	215_Y	1.066	0.33
101_W	173_A	1.061	0.33
280_V	285_V	1.061	0.33
80_L	176_A	1.060	0.33
3_A	276_L	1.059	0.33
26_L	297_I	1.057	0.32
191_R	251_D	1.053	0.32
199_L	278_E	1.047	0.32
147_A	154_H	1.045	0.32
78_F	234_V	1.036	0.32
278_E	305_H	1.036	0.32
97_I	155_A	1.035	0.31
63_M	305_H	1.030	0.31
215_Y	281_L	1.021	0.31
158_L	291_S	1.017	0.31
58_P	149_L	1.016	0.31
199_L	305_H	1.003	0.30
185_L	306_T	0.999	0.30
29_G	34_S	0.996	0.30
153_Q	257_P	0.991	0.30
108_G	250_T	0.988	0.29
24_M	230_Q	0.987	0.29
248_W	252_M	0.987	0.29
101_W	224_T	0.983	0.29
54_G	236_V	0.982	0.29
256_N	259_K	0.980	0.29
153_Q	253_V	0.980	0.29
36_S	100_T	0.969	0.29
200_G	264_E	0.966	0.28
182_R	200_G	0.966	0.28
88_A	92_G	0.965	0.28
236_V	240_I	0.963	0.28
61_L	131_K	0.963	0.28
12_L	39_F	0.962	0.28
64_R	283_S	0.958	0.28
29_G	234_V	0.956	0.28
15_A	19_I	0.956	0.28
237_S	252_M	0.956	0.28
182_R	247_F	0.955	0.28
247_F	264_E	0.955	0.28
65_K	281_L	0.951	0.28
167_V	299_I	0.946	0.28
175_F	198_V	0.942	0.27
42_M	74_S	0.939	0.27
30_S	219_S	0.929	0.27
11_S	144_L	0.927	0.27
237_S	241_I	0.926	0.27
83_A	208_F	0.925	0.27
22_R	278_E	0.920	0.27
85_I	134_L	0.920	0.27
48_L	211_I	0.918	0.26
42_M	234_V	0.917	0.26
48_L	272_I	0.910	0.26
219_S	236_V	0.909	0.26
292_F	299_I	0.909	0.26
11_S	153_Q	0.908	0.26
176_A	193_D	0.904	0.26
234_V	243_T	0.904	0.26
43_V	97_I	0.902	0.26
228_T	231_S	0.898	0.26
78_F	209_W	0.894	0.26
253_V	259_K	0.889	0.25
87_F	281_L	0.889	0.25
8_I	61_L	0.886	0.25
73_W	264_E	0.883	0.25
73_W	182_R	0.883	0.25
138_G	155_A	0.879	0.25
142_I	164_L	0.874	0.25
151_Q	200_G	0.866	0.24
142_I	161_R	0.863	0.24
183_R	306_T	0.857	0.24
111_L	278_E	0.854	0.24
182_R	221_G	0.852	0.24
221_G	264_E	0.852	0.24
98_A	275_L	0.839	0.23
81_F	177_Y	0.839	0.23
160_G	217_W	0.834	0.23
113_P	264_E	0.834	0.23
113_P	182_R	0.834	0.23
32_L	74_S	0.831	0.23
107_A	175_F	0.830	0.23
76_V	79_V	0.828	0.23
57_T	276_L	0.827	0.23
79_V	130_Q	0.822	0.23
115_F	129_R	0.822	0.23
2_K	304_L	0.822	0.23
53_R	147_A	0.821	0.23
57_T	61_L	0.819	0.23
22_R	98_A	0.817	0.23
2_K	148_A	0.815	0.23
33_W	97_I	0.814	0.22
73_W	108_G	0.813	0.22
237_S	279_I	0.812	0.22
25_E	204_A	0.811	0.22
10_A	88_A	0.810	0.22
59_L	70_W	0.809	0.22
48_L	279_I	0.807	0.22
8_I	269_G	0.805	0.22
17_T	21_N	0.805	0.22
105_I	268_S	0.804	0.22
20_L	29_G	0.804	0.22
83_A	205_S	0.803	0.22
32_L	103_I	0.803	0.22
174_A	231_S	0.794	0.22
36_S	175_F	0.791	0.22
111_L	298_I	0.787	0.22
18_F	101_W	0.784	0.21
15_A	24_M	0.783	0.21
5_V	135_V	0.780	0.21
74_S	84_P	0.778	0.21
51_I	211_I	0.777	0.21
76_V	152_L	0.774	0.21
81_F	242_A	0.773	0.21
206_L	240_I	0.772	0.21
107_A	269_G	0.772	0.21
149_L	297_I	0.769	0.21
218_W	283_S	0.764	0.21
221_G	250_T	0.761	0.21
185_L	250_T	0.761	0.21
66_K	187_E	0.761	0.21
107_A	257_P	0.755	0.20
34_S	42_M	0.753	0.20
112_S	116_Y	0.752	0.20
30_S	50_V	0.749	0.20
88_A	211_I	0.748	0.20
47_C	164_L	0.747	0.20
60_L	271_V	0.746	0.20
39_F	231_S	0.744	0.20
41_F	232_F	0.743	0.20
177_Y	234_V	0.738	0.20
276_L	288_S	0.731	0.20
96_L	264_E	0.731	0.20
96_L	182_R	0.731	0.20
131_K	292_F	0.727	0.19
42_M	94_G	0.726	0.19
77_G	205_S	0.722	0.19
61_L	142_I	0.722	0.19
12_L	270_E	0.720	0.19
288_S	292_F	0.719	0.19
86_T	257_P	0.719	0.19
47_C	106_V	0.717	0.19
289_L	292_F	0.716	0.19
3_A	166_S	0.716	0.19
13_F	238_S	0.716	0.19
11_S	257_P	0.715	0.19
52_M	171_V	0.712	0.19
97_I	107_A	0.712	0.19
3_A	252_M	0.711	0.19
73_W	179_L	0.710	0.19
253_V	272_I	0.709	0.19
89_A	166_S	0.709	0.19
10_A	251_D	0.708	0.19
54_G	283_S	0.708	0.19
43_V	241_I	0.708	0.19
75_F	288_S	0.708	0.19
113_P	247_F	0.704	0.19
142_I	152_L	0.703	0.19
9_L	222_L	0.703	0.19
130_Q	232_F	0.703	0.19
5_V	148_A	0.703	0.19
214_A	299_I	0.701	0.19
19_I	274_A	0.701	0.19
39_F	86_T	0.700	0.19
15_A	18_F	0.700	0.19
24_M	36_S	0.699	0.19
65_K	300_A	0.698	0.19
91_Y	141_V	0.697	0.19
200_G	247_F	0.696	0.18
182_R	185_L	0.696	0.18
185_L	264_E	0.696	0.18
68_F	145_I	0.695	0.18
151_Q	264_E	0.695	0.18
151_Q	182_R	0.695	0.18
72_K	296_F	0.695	0.18
15_A	193_D	0.691	0.18
73_W	183_R	0.690	0.18
99_G	186_E	0.688	0.18
101_W	105_I	0.688	0.18
59_L	295_L	0.686	0.18
86_T	288_S	0.685	0.18
97_I	233_I	0.683	0.18
85_I	198_V	0.683	0.18
108_G	247_F	0.678	0.18
2_K	106_V	0.677	0.18
91_Y	190_G	0.677	0.18
256_N	297_I	0.671	0.18
174_A	272_I	0.671	0.18
108_G	200_G	0.670	0.18
115_F	175_F	0.670	0.18
29_G	78_F	0.670	0.18
74_S	106_V	0.669	0.18
128_I	214_A	0.669	0.18
135_V	211_I	0.668	0.18
154_H	283_S	0.666	0.18
39_F	278_E	0.663	0.17
77_G	202_T	0.662	0.17
53_R	196_Q	0.660	0.17
92_G	163_L	0.658	0.17
262_A	307_F	0.651	0.17
149_L	203_L	0.648	0.17
3_A	174_A	0.645	0.17
65_K	210_L	0.645	0.17
44_P	113_P	0.644	0.17
55_T	216_G	0.642	0.17
25_E	94_G	0.641	0.17
69_Y	226_S	0.641	0.17
176_A	278_E	0.637	0.17
61_L	214_A	0.635	0.17
22_R	92_G	0.635	0.17
159_S	219_S	0.633	0.17
90_A	99_G	0.632	0.17
221_G	247_F	0.629	0.16
135_V	164_L	0.628	0.16
79_V	86_T	0.627	0.16
176_A	199_L	0.625	0.16
108_G	221_G	0.624	0.16
41_F	115_F	0.623	0.16
93_P	166_S	0.623	0.16
7_G	105_I	0.622	0.16
74_S	247_F	0.621	0.16
48_L	57_T	0.619	0.16
60_L	67_P	0.618	0.16
79_V	297_I	0.616	0.16
108_G	113_P	0.616	0.16
131_K	281_L	0.615	0.16
11_S	303_M	0.611	0.16
147_A	261_A	0.608	0.16
25_E	305_H	0.599	0.16
147_A	310_Q	0.598	0.16
86_T	136_S	0.597	0.16
141_V	226_S	0.597	0.16
15_A	231_S	0.596	0.16
9_L	153_Q	0.593	0.15
116_Y	295_L	0.591	0.15
97_I	174_A	0.590	0.15
18_F	105_I	0.589	0.15
6_I	237_S	0.588	0.15
66_K	157_S	0.586	0.15
40_I	168_L	0.584	0.15
43_V	163_L	0.584	0.15
62_E	99_G	0.583	0.15
234_V	271_V	0.582	0.15
43_V	203_L	0.582	0.15
214_A	218_W	0.580	0.15
76_V	261_A	0.580	0.15
107_A	158_L	0.577	0.15
50_V	185_L	0.576	0.15
99_G	231_S	0.576	0.15
247_F	250_T	0.573	0.15
42_M	78_F	0.573	0.15
41_F	231_S	0.571	0.15
260_L	268_S	0.571	0.15
236_V	280_V	0.571	0.15
16_V	135_V	0.570	0.15
135_V	229_V	0.570	0.15
136_S	255_D	0.570	0.15
163_L	166_S	0.570	0.15
99_G	150_I	0.569	0.15
11_S	194_T	0.569	0.15
8_I	276_L	0.567	0.15
162_M	281_L	0.567	0.15
262_A	282_L	0.567	0.15
116_Y	236_V	0.566	0.15
217_W	222_L	0.564	0.15
2_K	254_R	0.561	0.15
109_V	297_I	0.560	0.15
40_I	114_L	0.560	0.15
113_P	185_L	0.558	0.15
48_L	60_L	0.558	0.15
81_F	243_T	0.558	0.15
116_Y	147_A	0.557	0.15
164_L	303_M	0.554	0.14
94_G	305_H	0.554	0.14
71_I	205_S	0.550	0.14
12_L	255_D	0.550	0.14
75_F	208_F	0.550	0.14
56_F	288_S	0.549	0.14
200_G	250_T	0.549	0.14
225_A	293_A	0.548	0.14
36_S	173_A	0.547	0.14
39_F	286_F	0.547	0.14
7_G	266_T	0.544	0.14
21_N	37_L	0.543	0.14
62_E	65_K	0.543	0.14
72_K	165_F	0.542	0.14
165_F	171_V	0.542	0.14
63_M	142_I	0.542	0.14
14_F	21_N	0.541	0.14
106_V	174_A	0.541	0.14
5_V	9_L	0.539	0.14
35_S	212_L	0.539	0.14
297_I	308_A	0.539	0.14
142_I	299_I	0.539	0.14
171_V	224_T	0.538	0.14
106_V	204_A	0.538	0.14
158_L	174_A	0.538	0.14
6_I	86_T	0.537	0.14
103_I	147_A	0.537	0.14
23_A	282_L	0.536	0.14
85_I	270_E	0.534	0.14
84_P	176_A	0.533	0.14
6_I	19_I	0.533	0.14
53_R	191_R	0.531	0.14
29_G	37_L	0.530	0.14
105_I	140_S	0.530	0.14
88_A	99_G	0.529	0.14
174_A	292_F	0.527	0.14
225_A	299_I	0.521	0.14
269_G	284_G	0.520	0.14
176_A	209_W	0.518	0.14
97_I	142_I	0.517	0.14
22_R	28_G	0.516	0.13
59_L	170_V	0.516	0.13
107_A	112_S	0.515	0.13
90_A	204_A	0.514	0.13
55_T	91_Y	0.512	0.13
165_F	289_L	0.511	0.13
113_P	306_T	0.511	0.13
45_F	75_F	0.506	0.13
19_I	156_E	0.505	0.13
206_L	233_I	0.502	0.13
79_V	129_R	0.501	0.13
61_L	164_L	0.501	0.13
49_I	196_Q	0.500	0.13

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2i68A	2	0.2284	95.1	0.957	Contact Map
3b5dA	2	0.3117	87.4	0.965	Contact Map
2cfqA	1	0.9475	52.8	0.974	Contact Map
4ikvA	1	0.9259	51.2	0.974	Contact Map
4pypA	1	0.5617	43.3	0.975	Contact Map
1pw4A	1	0.6142	37.1	0.976	Contact Map
4xnjA	1	0.8827	35.1	0.976	Contact Map
4tphA	2	0.7099	27.8	0.978	Contact Map
3o7qA	1	0.7006	22.6	0.979	Contact Map
3wdoA	1	0.892	21.9	0.979	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0094 seconds.