CITS - BACSU - GREMLIN Contacts

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CITS - Sensor protein CitS

UniProt:	O34427	Sequences: MVKKRFHFSLQTKIMGLIAALLVFVIGVLTITLAVQHTQGERRQAEQLAVQTARTISYMPPVKELIERKDGHAAQTQEVIEQMKEQTGAFAIYVLNEKGDIRSASGKSGLKKLERSREILFGGSHVSETKADGRRVIRGSAPIIKEQKGYSQVIGSVSVDFLQTETEQSIKKHLRNLSVIAVLVLLLGFIGAAVLAKSIRKDTLGLEPHEIAALYRERNAMLFAIREGIIATNREGVVTMMNVSAAEMLKLPEPVIHLPIDDVMPGAGLMSVLEKGEMLPNQEVSVNDQVFIINTKVMNQGGQAYGIVVSFREKTELKKLIDTLTEVRKYSEDLRAQTHEFSNKLYAILGLLELGEYDEAIDLIKEEYAIQNEQHDLLFHNIHSQQVQAILLGKISKASEKKVKLVIDENSSLAPLPAHIGLSHLITIIGNLIDNAFEAVAEQSVKEVLFFITDMGHDIVIEVSDTGPGVPPEKIEAVFERGYSSKGMRRGYGLANVKDSVRELGGWIELANQKTGGAVFTVFIPKEKQRGNPFDSHRDCGG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	542 (505)
Sequences:	10327 (9025)
Seq/√Len:	401.6

ECOLI - DCUS DPIB ATOS RCSC RCSD BARA ARCB NARX EVGS TORS NARQ ZRAS PHOR CREC PHOQ CUSS BAES GLRK QSEC ENVZ YEDV CPXA NTRB
BACSU - CITS MALK DCTS YYCG RESE PHOR KINE KINA KINC KIND YCLK CSSS YKOH YVRG
HALSA - Q9HQ16 O51970 Q9HR10 Q9HRE4 Q9HQG5 Q9HRG1 Q9HNM2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
513_Q	516_G	4.324	1.00
464_S	519_V	4.305	1.00
352_L	364_I	3.933	1.00
475_I	510_L	3.915	1.00
383_H	386_Q	3.843	1.00
498_K	502_R	3.573	1.00
440_V	466_T	3.405	1.00
406_V	447_E	3.403	1.00
509_E	521_T	3.356	1.00
408_D	451_F	3.279	1.00
227_E	312_R	3.143	1.00
501_V	522_V	3.020	1.00
458_D	523_F	2.965	1.00
497_V	508_I	2.917	1.00
428_I	500_S	2.917	1.00
471_P	474_K	2.847	1.00
451_F	462_E	2.834	1.00
462_E	519_V	2.817	1.00
215_Y	219_N	2.796	1.00
233_N	237_V	2.776	1.00
449_L	464_S	2.769	1.00
510_L	520_F	2.739	1.00
460_V	523_F	2.720	1.00
420_I	504_L	2.703	1.00
465_D	469_G	2.673	1.00
408_D	449_L	2.652	1.00
406_V	449_L	2.649	1.00
214_L	217_E	2.649	1.00
470_V	474_K	2.635	1.00
461_I	522_V	2.598	1.00
453_T	460_V	2.541	1.00
500_S	504_L	2.526	1.00
462_E	521_T	2.500	1.00
244_S	247_E	2.496	1.00
317_L	321_I	2.385	1.00
324_L	327_V	2.361	1.00
511_A	519_V	2.357	1.00
404_K	447_E	2.332	1.00
512_N	518_A	2.329	1.00
447_E	466_T	2.322	1.00
451_F	464_S	2.321	1.00
501_V	506_G	2.292	1.00
428_I	501_V	2.273	1.00
475_I	512_N	2.255	1.00
429_I	461_I	2.228	1.00
258_L	262_D	2.225	1.00
428_I	497_V	2.155	1.00
460_V	521_T	2.128	1.00
395_I	399_S	2.086	1.00
349_L	368_Y	2.066	1.00
439_A	484_S	2.064	1.00
383_H	394_K	2.057	1.00
440_V	448_V	2.050	1.00
386_Q	390_I	2.034	1.00
479_F	508_I	2.024	1.00
454_D	526_K	2.023	1.00
96_N	100_D	2.015	1.00
477_A	480_E	1.998	1.00
321_I	325_T	1.955	1.00
421_G	424_H	1.948	1.00
507_W	523_F	1.910	1.00
386_Q	394_K	1.907	1.00
228_G	311_F	1.881	1.00
199_I	202_D	1.862	1.00
319_K	323_T	1.860	1.00
470_V	478_V	1.837	1.00
351_L	360_A	1.826	1.00
453_T	462_E	1.818	1.00
230_I	245_A	1.806	1.00
219_N	223_F	1.804	1.00
386_Q	393_G	1.803	1.00
383_H	393_G	1.800	1.00
225_I	229_I	1.795	1.00
511_A	521_T	1.794	1.00
192_A	196_A	1.783	1.00
212_A	215_Y	1.776	1.00
228_G	248_M	1.772	1.00
385_Q	394_K	1.762	1.00
385_Q	393_G	1.756	1.00
318_K	321_I	1.737	1.00
420_I	425_L	1.706	1.00
512_N	516_G	1.697	1.00
424_H	500_S	1.692	1.00
472_P	475_I	1.690	1.00
230_I	309_V	1.689	1.00
424_H	427_T	1.677	1.00
502_R	507_W	1.667	1.00
349_L	369_A	1.654	1.00
429_I	433_I	1.652	1.00
506_G	524_I	1.648	1.00
409_E	452_I	1.643	1.00
316_E	319_K	1.642	1.00
512_N	515_T	1.612	1.00
383_H	395_I	1.597	1.00
474_K	477_A	1.561	1.00
478_V	510_L	1.554	1.00
484_S	487_G	1.540	1.00
283_E	318_K	1.536	1.00
438_E	486_K	1.531	1.00
509_E	523_F	1.531	1.00
474_K	483_Y	1.522	1.00
243_V	247_E	1.519	1.00
259_P	262_D	1.509	1.00
440_V	444_S	1.504	1.00
155_G	162_L	1.493	1.00
251_L	254_P	1.478	1.00
388_Q	392_L	1.471	1.00
479_F	510_L	1.460	1.00
436_A	448_V	1.459	1.00
428_I	522_V	1.457	1.00
271_S	275_K	1.435	1.00
373_E	423_S	1.430	1.00
63_K	67_E	1.427	1.00
352_L	365_K	1.423	1.00
362_D	366_E	1.410	1.00
471_P	514_K	1.409	1.00
209_H	212_A	1.400	1.00
434_D	438_E	1.397	1.00
151_S	155_G	1.395	1.00
210_E	214_L	1.395	1.00
429_I	463_V	1.379	1.00
455_M	460_V	1.371	1.00
386_Q	395_I	1.357	1.00
81_E	84_K	1.352	1.00
432_L	522_V	1.346	1.00
218_R	221_M	1.344	1.00
319_K	322_D	1.343	1.00
477_A	483_Y	1.342	1.00
218_R	222_L	1.333	1.00
338_T	343_N	1.329	1.00
214_L	219_N	1.324	1.00
459_I	526_K	1.324	1.00
347_A	351_L	1.322	1.00
322_D	325_T	1.321	1.00
52_T	55_T	1.314	1.00
480_E	483_Y	1.313	1.00
350_G	354_L	1.313	1.00
283_E	286_V	1.312	1.00
211_I	214_L	1.312	1.00
142_P	155_G	1.310	1.00
230_I	238_V	1.309	1.00
106_G	109_G	1.307	1.00
355_G	358_D	1.304	1.00
113_L	116_S	1.298	1.00
383_H	390_I	1.298	1.00
348_I	364_I	1.296	1.00
31_I	35_V	1.290	1.00
501_V	508_I	1.285	1.00
394_K	430_G	1.282	1.00
243_V	246_A	1.280	1.00
214_L	218_R	1.274	1.00
45_A	49_A	1.274	1.00
389_A	393_G	1.268	1.00
232_T	309_V	1.265	1.00
241_M	245_A	1.264	1.00
270_M	274_E	1.262	1.00
273_L	276_G	1.260	1.00
384_S	388_Q	1.254	1.00
246_A	252_P	1.253	1.00
470_V	510_L	1.250	1.00
470_V	518_A	1.247	1.00
265_P	268_G	1.246	1.00
323_T	326_E	1.238	1.00
215_Y	218_R	1.237	1.00
425_L	504_L	1.236	1.00
241_M	246_A	1.234	1.00
365_K	369_A	1.230	1.00
372_N	376_D	1.230	1.00
347_A	367_E	1.229	1.00
228_G	245_A	1.219	1.00
393_G	397_K	1.217	1.00
228_G	242_N	1.213	1.00
245_A	249_L	1.204	1.00
472_P	513_Q	1.198	1.00
478_V	520_F	1.198	1.00
337_Q	378_L	1.194	1.00
386_Q	389_A	1.192	1.00
42_R	46_E	1.181	1.00
38_T	42_R	1.180	1.00
441_A	444_S	1.177	1.00
197_K	201_K	1.175	1.00
231_A	306_G	1.174	1.00
112_K	115_R	1.174	1.00
410_N	453_T	1.173	1.00
458_D	507_W	1.170	1.00
440_V	443_Q	1.169	1.00
320_L	323_T	1.169	1.00
320_L	324_L	1.160	1.00
424_H	503_E	1.160	1.00
49_A	52_T	1.157	1.00
479_F	520_F	1.156	1.00
340_E	343_N	1.142	1.00
196_A	200_R	1.133	1.00
318_K	322_D	1.131	1.00
112_K	116_S	1.127	1.00
328_R	332_E	1.124	1.00
449_L	466_T	1.123	1.00
474_K	485_S	1.117	1.00
510_L	518_A	1.116	1.00
432_L	463_V	1.116	1.00
65_L	69_K	1.114	1.00
91_A	160_D	1.113	1.00
232_T	238_V	1.108	1.00
49_A	53_A	1.105	1.00
347_A	363_L	1.098	1.00
242_N	245_A	1.094	1.00
398_A	437_F	1.094	1.00
317_L	324_L	1.093	1.00
385_Q	396_S	1.090	1.00
297_V	306_G	1.089	1.00
398_A	405_L	1.089	1.00
386_Q	396_S	1.085	1.00
222_L	240_M	1.084	1.00
391_L	394_K	1.083	1.00
328_R	331_S	1.082	1.00
76_T	80_I	1.079	1.00
390_I	393_G	1.074	1.00
335_R	340_E	1.073	1.00
386_Q	391_L	1.073	1.00
388_Q	452_I	1.063	1.00
351_L	363_L	1.060	1.00
65_L	68_R	1.058	1.00
212_A	216_R	1.052	1.00
470_V	475_I	1.049	1.00
297_V	304_A	1.048	1.00
363_L	367_E	1.043	1.00
341_F	344_K	1.043	1.00
392_L	395_I	1.042	1.00
393_G	426_I	1.040	1.00
385_Q	389_A	1.035	1.00
44_Q	47_Q	1.031	1.00
427_T	500_S	1.026	1.00
468_P	487_G	1.023	1.00
35_V	39_Q	1.019	1.00
492_Y	496_N	1.019	1.00
341_F	371_Q	1.018	1.00
152_Q	155_G	1.017	1.00
190_I	194_V	1.016	1.00
50_V	54_R	1.013	1.00
426_I	430_G	1.009	1.00
33_L	37_H	1.009	1.00
432_L	497_V	0.998	1.00
389_A	426_I	0.998	1.00
295_T	298_M	0.995	1.00
241_M	255_V	0.990	1.00
509_E	522_V	0.990	1.00
299_N	304_A	0.987	1.00
452_I	461_I	0.983	1.00
282_Q	285_S	0.979	1.00
359_E	363_L	0.978	1.00
346_Y	349_L	0.977	1.00
359_E	362_D	0.968	1.00
433_I	450_F	0.967	1.00
343_N	439_A	0.965	1.00
317_L	320_L	0.961	1.00
422_L	426_I	0.961	1.00
383_H	388_Q	0.960	1.00
390_I	394_K	0.960	1.00
413_L	452_I	0.959	1.00
295_T	307_I	0.958	1.00
443_Q	466_T	0.958	1.00
118_E	122_G	0.957	1.00
222_L	229_I	0.955	1.00
339_H	431_N	0.952	1.00
223_F	243_V	0.951	1.00
349_L	352_L	0.950	1.00
117_R	121_F	0.950	1.00
229_I	310_S	0.949	1.00
289_Q	292_I	0.949	1.00
432_L	520_F	0.947	1.00
419_H	527_E	0.943	1.00
364_I	368_Y	0.941	1.00
351_L	364_I	0.939	1.00
82_Q	86_Q	0.938	1.00
41_E	45_A	0.937	1.00
501_V	524_I	0.934	1.00
385_Q	390_I	0.933	1.00
398_A	448_V	0.932	1.00
470_V	512_N	0.930	1.00
68_R	71_G	0.929	1.00
450_F	463_V	0.928	1.00
428_I	504_L	0.926	1.00
410_N	413_L	0.924	1.00
342_S	379_F	0.923	1.00
391_L	395_I	0.922	1.00
340_E	344_K	0.921	1.00
174_L	178_S	0.921	1.00
385_Q	422_L	0.920	1.00
95_L	101_I	0.917	1.00
349_L	353_E	0.914	1.00
35_V	38_T	0.914	1.00
155_G	159_V	0.912	1.00
198_S	202_D	0.907	1.00
93_Y	101_I	0.907	1.00
481_R	499_D	0.901	1.00
111_K	115_R	0.900	1.00
377_L	424_H	0.899	1.00
245_A	248_M	0.897	1.00
231_A	240_M	0.896	1.00
134_R	138_R	0.895	1.00
294_N	312_R	0.895	1.00
231_A	308_V	0.892	1.00
457_H	526_K	0.891	1.00
352_L	361_I	0.887	1.00
342_S	371_Q	0.885	1.00
30_T	34_A	0.880	1.00
470_V	476_E	0.880	1.00
232_T	236_G	0.877	1.00
43_R	46_E	0.876	1.00
132_D	136_V	0.876	1.00
246_A	255_V	0.872	1.00
353_E	365_K	0.872	1.00
389_A	422_L	0.872	1.00
397_K	400_E	0.869	1.00
341_F	374_Q	0.866	1.00
45_A	48_L	0.866	1.00
48_L	51_Q	0.865	1.00
342_S	372_N	0.865	1.00
29_L	33_L	0.862	1.00
314_K	318_K	0.854	1.00
78_E	81_E	0.850	1.00
48_L	52_T	0.850	1.00
211_I	215_Y	0.848	1.00
118_E	123_G	0.848	1.00
340_E	427_T	0.846	1.00
367_E	370_I	0.845	1.00
348_I	368_Y	0.844	1.00
79_V	83_M	0.843	1.00
202_D	206_L	0.841	1.00
222_L	242_N	0.841	1.00
380_H	424_H	0.839	1.00
433_I	448_V	0.839	1.00
144_I	153_V	0.837	1.00
383_H	396_S	0.835	1.00
119_I	123_G	0.834	1.00
291_F	294_N	0.834	1.00
352_L	368_Y	0.833	1.00
67_E	70_D	0.832	1.00
86_Q	89_A	0.829	1.00
394_K	398_A	0.828	1.00
354_L	360_A	0.828	1.00
129_T	132_D	0.825	1.00
91_A	104_A	0.820	1.00
396_S	399_S	0.820	1.00
425_L	522_V	0.819	1.00
79_V	82_Q	0.818	1.00
397_K	401_K	0.818	1.00
333_D	337_Q	0.815	1.00
349_L	372_N	0.814	1.00
340_E	496_N	0.814	1.00
381_N	499_D	0.813	1.00
341_F	375_H	0.813	1.00
244_S	248_M	0.812	1.00
228_G	249_L	0.812	1.00
162_L	165_E	0.811	1.00
136_V	139_G	0.811	1.00
225_I	228_G	0.809	1.00
171_K	174_L	0.809	1.00
59_M	62_V	0.807	1.00
41_E	44_Q	0.806	1.00
378_L	382_I	0.804	1.00
499_D	502_R	0.803	1.00
27_G	31_I	0.802	1.00
336_A	481_R	0.802	1.00
239_T	306_G	0.801	1.00
360_A	363_L	0.801	1.00
317_L	323_T	0.799	1.00
233_N	239_T	0.799	1.00
392_L	396_S	0.799	1.00
225_I	310_S	0.798	1.00
44_Q	48_L	0.797	1.00
341_F	345_L	0.794	1.00
333_D	343_N	0.793	1.00
237_V	259_P	0.793	1.00
506_G	525_P	0.791	1.00
96_N	99_G	0.791	1.00
402_K	442_E	0.791	1.00
129_T	140_S	0.790	1.00
81_E	85_E	0.789	1.00
403_V	440_V	0.788	1.00
439_A	487_G	0.787	1.00
334_L	337_Q	0.787	1.00
465_D	517_G	0.787	1.00
138_R	160_D	0.786	1.00
344_K	371_Q	0.784	1.00
140_S	156_S	0.782	1.00
64_E	68_R	0.781	1.00
438_E	484_S	0.780	1.00
468_P	518_A	0.779	1.00
335_R	374_Q	0.777	1.00
338_T	342_S	0.776	1.00
331_S	335_R	0.775	1.00
204_L	208_P	0.772	1.00
271_S	276_G	0.772	1.00
133_G	136_V	0.770	1.00
332_E	336_A	0.768	1.00
158_S	162_L	0.768	1.00
343_N	350_G	0.766	1.00
276_G	279_L	0.766	1.00
497_V	501_V	0.765	1.00
455_M	458_D	0.764	1.00
427_T	496_N	0.761	1.00
217_E	221_M	0.761	1.00
439_A	486_K	0.758	1.00
229_I	242_N	0.756	1.00
332_E	481_R	0.756	1.00
333_D	338_T	0.755	1.00
289_Q	313_E	0.755	1.00
213_A	217_E	0.752	1.00
66_I	70_D	0.750	1.00
242_N	315_T	0.750	1.00
295_T	309_V	0.748	1.00
342_S	376_D	0.748	1.00
65_L	70_D	0.747	1.00
138_R	141_A	0.745	1.00
401_K	405_L	0.742	1.00
280_P	283_E	0.739	1.00
429_I	522_V	0.737	1.00
209_H	213_A	0.735	1.00
75_Q	79_V	0.734	1.00
408_D	453_T	0.733	1.00
163_Q	167_E	0.733	1.00
391_L	407_I	0.733	1.00
323_T	327_V	0.732	1.00
145_K	154_I	0.732	1.00
484_S	488_M	0.730	1.00
76_T	83_M	0.728	1.00
288_D	292_I	0.728	1.00
340_E	431_N	0.728	1.00
140_S	158_S	0.726	1.00
111_K	114_E	0.725	1.00
32_T	36_Q	0.724	1.00
501_V	504_L	0.724	1.00
403_V	437_F	0.723	1.00
210_E	215_Y	0.722	1.00
367_E	371_Q	0.722	1.00
34_A	38_T	0.717	1.00
296_K	308_V	0.716	1.00
438_E	485_S	0.715	1.00
381_N	481_R	0.715	1.00
337_Q	341_F	0.715	1.00
217_E	240_M	0.715	1.00
264_M	268_G	0.713	1.00
142_P	154_I	0.713	1.00
385_Q	388_Q	0.712	1.00
335_R	492_Y	0.712	1.00
330_Y	334_L	0.711	1.00
272_V	275_K	0.711	1.00
351_L	367_E	0.711	1.00
186_L	190_I	0.710	1.00
145_K	152_Q	0.709	1.00
36_Q	40_G	0.708	1.00
394_K	437_F	0.708	1.00
476_E	480_E	0.707	1.00
299_N	302_G	0.707	1.00
101_I	104_A	0.706	1.00
175_R	179_V	0.706	1.00
334_L	343_N	0.705	1.00
205_G	208_P	0.703	1.00
141_A	144_I	0.701	1.00
333_D	379_F	0.700	1.00
232_T	295_T	0.700	1.00
397_K	434_D	0.699	1.00
172_K	175_R	0.699	1.00
93_Y	96_N	0.698	1.00
462_E	511_A	0.697	1.00
314_K	317_L	0.697	1.00
379_F	490_R	0.697	1.00
93_Y	104_A	0.696	1.00
157_V	162_L	0.696	1.00
436_A	463_V	0.693	1.00
75_Q	78_E	0.693	1.00
289_Q	293_I	0.693	1.00
66_I	71_G	0.692	1.00
331_S	340_E	0.692	1.00
238_V	242_N	0.690	1.00
144_I	155_G	0.689	1.00
118_E	121_F	0.689	1.00
481_R	495_A	0.688	1.00
248_M	291_F	0.687	1.00
458_D	526_K	0.687	1.00
65_L	71_G	0.686	1.00
95_L	158_S	0.685	1.00
377_L	490_R	0.683	0.99
403_V	448_V	0.683	0.99
484_S	490_R	0.682	0.99
447_E	464_S	0.682	0.99
384_S	452_I	0.681	0.99
171_K	175_R	0.680	0.99
384_S	394_K	0.679	0.99
62_V	66_I	0.678	0.99
325_T	328_R	0.678	0.99
373_E	377_L	0.677	0.99
269_L	273_L	0.676	0.99
176_N	179_V	0.675	0.99
224_A	308_V	0.674	0.99
376_D	380_H	0.673	0.99
282_Q	286_V	0.673	0.99
470_V	494_L	0.672	0.99
333_D	484_S	0.672	0.99
80_I	84_K	0.671	0.99
306_G	311_F	0.670	0.99
230_I	311_F	0.670	0.99
366_E	389_A	0.668	0.99
139_G	142_P	0.667	0.99
155_G	161_F	0.666	0.99
46_E	49_A	0.664	0.99
401_K	437_F	0.663	0.99
181_A	185_L	0.663	0.99
198_S	201_K	0.663	0.99
338_T	439_A	0.662	0.99
155_G	163_Q	0.662	0.99
472_P	476_E	0.661	0.99
189_F	193_A	0.661	0.99
258_L	263_V	0.661	0.99
193_A	197_K	0.660	0.99
221_M	224_A	0.659	0.99
53_A	159_V	0.658	0.99
227_E	244_S	0.658	0.99
427_T	430_G	0.657	0.99
188_G	192_A	0.656	0.99
402_K	443_Q	0.655	0.99
281_N	285_S	0.653	0.99
508_I	522_V	0.653	0.99
11_Q	197_K	0.652	0.99
51_Q	55_T	0.650	0.99
132_D	138_R	0.649	0.99
222_L	231_A	0.648	0.99
340_E	374_Q	0.648	0.99
390_I	433_I	0.647	0.99
343_N	347_A	0.645	0.99
335_R	341_F	0.643	0.99
413_L	418_A	0.643	0.99
53_A	57_S	0.643	0.99
82_Q	85_E	0.642	0.99
481_R	492_Y	0.642	0.99
272_V	307_I	0.641	0.99
471_P	478_V	0.640	0.99
230_I	242_N	0.640	0.99
368_Y	372_N	0.638	0.99
245_A	309_V	0.638	0.99
231_A	239_T	0.637	0.99
384_S	409_E	0.636	0.99
47_Q	51_Q	0.636	0.99
458_D	525_P	0.635	0.99
455_M	523_F	0.632	0.99
315_T	319_K	0.631	0.99
339_H	343_N	0.631	0.99
63_K	70_D	0.631	0.99
221_M	231_A	0.630	0.99
360_A	364_I	0.629	0.99
228_G	313_E	0.628	0.99
343_N	438_E	0.627	0.99
217_E	222_L	0.627	0.99
38_T	41_E	0.626	0.99
462_E	522_V	0.625	0.99
239_T	242_N	0.624	0.99
373_E	376_D	0.624	0.99
111_K	116_S	0.624	0.99
439_A	468_P	0.623	0.99
335_R	343_N	0.622	0.99
336_A	486_K	0.622	0.99
136_V	160_D	0.621	0.99
155_G	160_D	0.621	0.99
344_K	482_G	0.619	0.99
292_I	312_R	0.617	0.99
346_Y	352_L	0.616	0.99
403_V	466_T	0.615	0.99
231_A	245_A	0.613	0.99
270_M	276_G	0.612	0.99
273_L	277_E	0.612	0.99
335_R	338_T	0.612	0.99
73_A	76_T	0.611	0.99
346_Y	350_G	0.611	0.99
125_H	140_S	0.610	0.99
469_G	517_G	0.609	0.99
96_N	102_R	0.607	0.99
76_T	79_V	0.607	0.99
242_N	248_M	0.607	0.99
343_N	379_F	0.605	0.99
350_G	368_Y	0.601	0.99
220_A	224_A	0.601	0.99
479_F	498_K	0.601	0.99
470_V	520_F	0.600	0.99
393_G	396_S	0.600	0.99
343_N	354_L	0.599	0.99
341_F	351_L	0.598	0.99
347_A	350_G	0.597	0.99
342_S	346_Y	0.596	0.99
330_Y	336_A	0.596	0.99
117_R	120_L	0.596	0.99
322_D	326_E	0.595	0.99
59_M	63_K	0.595	0.99
391_L	450_F	0.595	0.99
249_L	311_F	0.595	0.99
438_E	487_G	0.595	0.99
74_A	78_E	0.594	0.99
343_N	440_V	0.593	0.99
482_G	495_A	0.593	0.99
522_V	525_P	0.593	0.99
131_A	138_R	0.593	0.99
106_G	110_L	0.591	0.99
383_H	461_I	0.591	0.99
216_R	220_A	0.590	0.99
336_A	381_N	0.590	0.99
53_A	56_I	0.589	0.99
350_G	427_T	0.588	0.99
470_V	479_F	0.588	0.99
31_I	34_A	0.588	0.99
128_E	132_D	0.587	0.98
134_R	141_A	0.586	0.98
435_N	493_G	0.585	0.98
212_A	218_R	0.584	0.98
201_K	204_L	0.583	0.98
385_Q	398_A	0.583	0.98
371_Q	377_L	0.583	0.98
200_R	203_T	0.582	0.98
440_V	484_S	0.582	0.98
346_Y	351_L	0.582	0.98
182_V	186_L	0.579	0.98
431_N	490_R	0.578	0.98
224_A	231_A	0.578	0.98
370_I	374_Q	0.577	0.98
118_E	125_H	0.577	0.98
439_A	485_S	0.576	0.98
217_E	231_A	0.575	0.98
293_I	297_V	0.574	0.98
424_H	428_I	0.574	0.98
424_H	504_L	0.574	0.98
138_R	143_I	0.574	0.98
343_N	346_Y	0.573	0.98
196_A	199_I	0.573	0.98
385_Q	391_L	0.571	0.98
177_L	180_I	0.571	0.98
368_Y	371_Q	0.570	0.98
425_L	501_V	0.569	0.98
423_S	426_I	0.569	0.98
141_A	145_K	0.569	0.98
231_A	309_V	0.568	0.98
371_Q	378_L	0.568	0.98
245_A	311_F	0.567	0.98
246_A	251_L	0.567	0.98
137_I	140_S	0.566	0.98
346_Y	354_L	0.566	0.98
234_R	304_A	0.565	0.98
336_A	343_N	0.564	0.98
430_G	434_D	0.564	0.98
64_E	69_K	0.564	0.98
12_T	15_M	0.563	0.98
230_I	241_M	0.563	0.98
156_S	160_D	0.562	0.98
269_L	272_V	0.562	0.98
249_L	291_F	0.559	0.98
79_V	87_T	0.558	0.98
347_A	354_L	0.558	0.98
221_M	308_V	0.557	0.98
369_A	373_E	0.557	0.98
321_I	324_L	0.556	0.98
93_Y	99_G	0.555	0.98
94_V	157_V	0.554	0.98
346_Y	481_R	0.554	0.98
370_I	426_I	0.554	0.98
234_R	303_Q	0.552	0.98
73_A	77_Q	0.552	0.98
231_A	242_N	0.550	0.98
237_V	257_H	0.550	0.98
344_K	375_H	0.550	0.98
508_I	520_F	0.549	0.98
342_S	367_E	0.549	0.98
238_V	257_H	0.548	0.98
43_R	47_Q	0.547	0.98
164_T	168_Q	0.547	0.98
494_L	520_F	0.546	0.98
117_R	123_G	0.546	0.98
471_P	485_S	0.545	0.98
221_M	228_G	0.545	0.98
361_I	364_I	0.545	0.98
107_K	110_L	0.544	0.98
393_G	430_G	0.544	0.98
431_N	434_D	0.543	0.98
87_T	90_F	0.542	0.97
431_N	496_N	0.541	0.97
26_I	34_A	0.541	0.97
225_I	308_V	0.541	0.97
39_Q	42_R	0.540	0.97
290_V	293_I	0.540	0.97
260_I	263_V	0.539	0.97
46_E	50_V	0.539	0.97
385_Q	420_I	0.539	0.97
230_I	233_N	0.538	0.97
25_V	29_L	0.538	0.97
230_I	236_G	0.535	0.97
155_G	158_S	0.535	0.97
227_E	310_S	0.534	0.97
346_Y	367_E	0.534	0.97
101_I	105_S	0.533	0.97
370_I	430_G	0.533	0.97
384_S	395_I	0.532	0.97
18_I	23_V	0.532	0.97
16_G	20_A	0.530	0.97
346_Y	353_E	0.529	0.97
433_I	463_V	0.529	0.97
343_N	371_Q	0.528	0.97
292_I	317_L	0.527	0.97
129_T	138_R	0.527	0.97
345_L	351_L	0.525	0.97
64_E	67_E	0.525	0.97
410_N	452_I	0.525	0.97
159_V	162_L	0.524	0.97
120_L	124_S	0.524	0.97
425_L	524_I	0.523	0.97
232_T	260_I	0.523	0.97
275_K	279_L	0.523	0.97
166_T	170_I	0.523	0.97
146_E	151_S	0.523	0.97
47_Q	50_V	0.522	0.97
307_I	311_F	0.522	0.97
367_E	379_F	0.522	0.97
394_K	433_I	0.521	0.97
344_K	496_N	0.521	0.97
388_Q	407_I	0.520	0.97
77_Q	80_I	0.519	0.97
387_V	394_K	0.517	0.97
22_L	25_V	0.517	0.97
404_K	407_I	0.517	0.97
228_G	232_T	0.516	0.97
501_V	507_W	0.515	0.97
129_T	136_V	0.514	0.97
153_V	157_V	0.514	0.97
334_L	346_Y	0.513	0.97
229_I	240_M	0.512	0.96
209_H	215_Y	0.511	0.96
438_E	488_M	0.510	0.96
78_E	82_Q	0.510	0.96
330_Y	338_T	0.510	0.96
39_Q	43_R	0.509	0.96
195_L	199_I	0.509	0.96
76_T	103_S	0.508	0.96
343_N	484_S	0.508	0.96
77_Q	81_E	0.508	0.96
343_N	375_H	0.507	0.96
214_L	221_M	0.507	0.96
251_L	255_V	0.507	0.96
84_K	87_T	0.506	0.96
99_G	105_S	0.506	0.96
194_V	198_S	0.506	0.96
257_H	263_V	0.506	0.96
383_H	389_A	0.506	0.96
140_S	143_I	0.503	0.96
192_A	200_R	0.503	0.96
93_Y	105_S	0.503	0.96
444_S	466_T	0.503	0.96
484_S	489_R	0.503	0.96
42_R	45_A	0.502	0.96
136_V	140_S	0.502	0.96
242_N	313_E	0.501	0.96
367_E	481_R	0.501	0.96
134_R	140_S	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.5941	100	0.458	Contact Map
4gczA	2	0.6052	100	0.465	Contact Map
3a0rA	2	0.5609	100	0.473	Contact Map
4r3aA	1	0.5406	100	0.563	Contact Map
2c2aA	2	0.3948	100	0.603	Contact Map
3jz3A	2	0.2583	100	0.616	Contact Map
4q20A	2	0.3727	100	0.617	Contact Map
3d36A	2	0.3708	100	0.619	Contact Map
4e01A	3	0.4945	100	0.621	Contact Map
4mpcA	2	0.5461	100	0.621	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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