G3P2 - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

G3P2 - Glyceraldehyde-3-phosphate dehydrogenase 2

UniProt:	O34425	Sequences: MKVKVAINGFGRIGRMVFRKAMLDDQIQVVAINASYSAETLAHLIKYDTIHGRYDKEVVAGEDSLIVNGKKVLLLNSRDPKQLPWREYDIDIVVEATGKFNAKDKAMGHIEAGAKKVILTAPGKNEDVTIVMGVNEDQFDAERHVIISNASCTTNCLAPVVKVLDEEFGIESGLMTTVHAYTNDQKNIDNPHKDLRRARACGESIIPTTTGAAKALSLVLPHLKGKLHGLALRVPVPNVSLVDLVVDLKTDVTAEEVNEAFKRAAKTSMYGVLDYSDEPLVSTDYNTNPHSAVIDGLTTMVMEDRKVKVLAWYDNEWGYSCRVVDLIRHVAARMKHPSAV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	340 (328)
Sequences:	5439 (2479)
Seq/√Len:	136.9

ECOLI - E4PD G3P1 G3P3
BACSU - G3P2 G3P1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
165_D	222_H	4.264	1.00
77_S	82_Q	3.655	1.00
171_E	249_K	3.377	1.00
162_K	166_E	3.176	1.00
274_D	290_H	3.091	1.00
107_M	111_E	2.801	1.00
136_E	329_H	2.792	1.00
204_S	283_T	2.759	1.00
251_D	305_R	2.742	1.00
79_D	82_Q	2.715	1.00
168_F	260_A	2.490	1.00
261_F	294_I	2.478	1.00
167_E	263_R	2.464	1.00
181_Y	202_G	2.451	1.00
4_K	28_Q	2.451	1.00
56_K	68_N	2.428	1.00
292_A	311_A	2.349	1.00
64_S	71_K	2.320	1.00
147_I	330_V	2.295	1.00
61_G	71_K	2.254	1.00
105_K	108_G	2.241	1.00
102_A	105_K	2.207	1.00
172_S	247_D	2.177	1.00
232_L	241_L	2.172	1.00
291_S	322_R	2.114	1.00
238_N	286_N	2.086	1.00
257_V	307_V	2.032	1.00
250_T	256_E	2.023	1.00
140_D	143_R	2.013	1.00
132_M	136_E	2.009	1.00
61_G	64_S	1.941	1.00
46_K	278_E	1.941	1.00
22_M	54_Y	1.917	1.00
180_A	236_V	1.905	1.00
28_Q	70_K	1.896	1.00
217_S	224_K	1.879	1.00
21_A	29_V	1.873	1.00
259_E	263_R	1.869	1.00
80_P	100_F	1.862	1.00
205_I	232_L	1.860	1.00
40_T	195_L	1.852	1.00
251_D	304_D	1.851	1.00
103_K	107_M	1.840	1.00
51_H	238_N	1.811	1.00
239_V	285_Y	1.795	1.00
161_V	223_L	1.794	1.00
84_P	87_E	1.781	1.00
81_K	111_E	1.763	1.00
10_F	45_I	1.762	1.00
262_K	277_D	1.761	1.00
81_K	108_G	1.729	1.00
18_F	29_V	1.719	1.00
275_Y	296_G	1.718	1.00
228_H	300_M	1.710	1.00
128_V	138_Q	1.692	1.00
116_K	145_V	1.691	1.00
248_L	307_V	1.676	1.00
274_D	288_N	1.659	1.00
20_K	321_C	1.654	1.00
118_I	327_I	1.635	1.00
96_A	120_T	1.620	1.00
18_F	45_I	1.611	1.00
279_P	297_L	1.608	1.00
94_V	327_I	1.579	1.00
18_F	67_V	1.579	1.00
161_V	170_I	1.578	1.00
322_R	325_D	1.578	1.00
258_N	299_T	1.576	1.00
171_E	305_R	1.574	1.00
120_T	323_V	1.551	1.00
49_T	203_E	1.549	1.00
262_K	266_K	1.544	1.00
171_E	247_D	1.535	1.00
73_L	87_E	1.513	1.00
184_D	192_H	1.493	1.00
64_S	73_L	1.484	1.00
102_A	124_K	1.475	1.00
4_K	89_D	1.465	1.00
101_N	119_L	1.455	1.00
38_A	74_L	1.443	1.00
123_G	126_E	1.426	1.00
43_H	198_A	1.415	1.00
107_M	110_I	1.410	1.00
168_F	248_L	1.401	1.00
203_E	237_P	1.391	1.00
103_K	127_D	1.380	1.00
276_S	285_Y	1.377	1.00
49_T	283_T	1.372	1.00
288_N	293_V	1.369	1.00
24_D	328_R	1.357	1.00
160_V	311_A	1.354	1.00
187_N	201_C	1.350	1.00
53_R	288_N	1.345	1.00
75_L	88_Y	1.335	1.00
253_T	256_E	1.329	1.00
218_L	224_K	1.321	1.00
43_H	195_L	1.311	1.00
276_S	280_L	1.299	1.00
183_N	188_I	1.298	1.00
106_A	119_L	1.298	1.00
160_V	292_A	1.296	1.00
94_V	323_V	1.293	1.00
31_A	75_L	1.288	1.00
254_A	299_T	1.282	1.00
172_S	303_E	1.269	1.00
23_L	55_D	1.264	1.00
290_H	293_V	1.264	1.00
197_R	208_T	1.263	1.00
247_D	305_R	1.258	1.00
262_K	275_Y	1.246	1.00
164_L	261_F	1.242	1.00
280_L	285_Y	1.241	1.00
173_G	227_L	1.240	1.00
200_A	203_E	1.239	1.00
163_V	273_L	1.235	1.00
96_A	323_V	1.230	1.00
92_I	327_I	1.207	1.00
79_D	108_G	1.194	1.00
172_S	305_R	1.192	1.00
167_E	260_A	1.184	1.00
61_G	66_I	1.180	0.99
38_A	60_A	1.179	0.99
128_V	143_R	1.177	0.99
163_V	260_A	1.175	0.99
194_D	197_R	1.165	0.99
291_S	325_D	1.159	0.99
277_D	296_G	1.157	0.99
186_K	190_N	1.154	0.99
165_D	220_L	1.153	0.99
283_T	286_N	1.153	0.99
83_L	88_Y	1.149	0.99
269_M	273_L	1.135	0.99
102_A	125_N	1.134	0.99
18_F	72_V	1.130	0.99
317_W	321_C	1.127	0.99
164_L	309_V	1.127	0.99
54_Y	68_N	1.118	0.99
248_L	252_V	1.117	0.99
183_N	190_N	1.115	0.99
167_E	171_E	1.109	0.99
160_V	261_F	1.107	0.99
17_V	320_S	1.100	0.99
16_M	51_H	1.092	0.99
17_V	323_V	1.087	0.99
104_D	125_N	1.083	0.99
17_V	94_V	1.075	0.99
259_E	262_K	1.070	0.99
26_Q	328_R	1.069	0.99
298_T	310_L	1.067	0.99
252_V	301_V	1.066	0.99
289_P	317_W	1.064	0.99
66_I	71_K	1.060	0.99
42_A	58_V	1.059	0.99
178_V	232_L	1.055	0.99
319_Y	323_V	1.055	0.99
6_A	83_L	1.055	0.99
168_F	252_V	1.052	0.99
119_L	123_G	1.052	0.99
36_Y	191_P	1.051	0.99
169_G	248_L	1.046	0.99
301_V	307_V	1.046	0.99
23_L	287_T	1.043	0.99
230_L	310_L	1.038	0.99
41_L	74_L	1.027	0.99
47_Y	278_E	1.022	0.99
45_I	56_K	1.019	0.98
165_D	249_K	1.018	0.98
66_I	69_G	1.017	0.98
252_V	256_E	1.016	0.98
241_L	310_L	1.015	0.98
37_S	40_T	1.014	0.98
160_V	309_V	1.012	0.98
139_F	147_I	1.010	0.98
50_I	237_P	1.007	0.98
103_K	126_E	1.006	0.98
139_F	145_V	1.000	0.98
164_L	248_L	1.000	0.98
6_A	90_I	0.998	0.98
63_D	73_L	0.997	0.98
138_Q	222_H	0.993	0.98
116_K	139_F	0.992	0.98
83_L	112_A	0.989	0.98
129_T	218_L	0.983	0.98
123_G	129_T	0.981	0.98
255_E	259_E	0.979	0.98
265_A	268_S	0.978	0.98
168_F	257_V	0.976	0.98
92_I	118_I	0.970	0.98
236_V	239_V	0.967	0.98
196_R	295_D	0.965	0.98
276_S	297_L	0.962	0.98
172_S	306_K	0.960	0.98
22_M	70_K	0.958	0.98
254_A	258_N	0.957	0.98
157_L	175_M	0.955	0.98
289_P	321_C	0.952	0.98
260_A	263_R	0.949	0.98
118_I	147_I	0.949	0.98
91_D	115_K	0.944	0.98
35_S	97_T	0.944	0.98
104_D	107_M	0.942	0.97
108_G	112_A	0.936	0.97
184_D	197_R	0.926	0.97
73_L	88_Y	0.926	0.97
163_V	269_M	0.925	0.97
232_L	310_L	0.920	0.97
51_H	287_T	0.918	0.97
50_I	238_N	0.916	0.97
301_V	304_D	0.908	0.97
3_V	27_I	0.898	0.97
31_A	90_I	0.897	0.97
252_V	260_A	0.895	0.97
90_I	93_V	0.890	0.96
273_L	292_A	0.880	0.96
164_L	246_V	0.877	0.96
75_L	84_P	0.876	0.96
132_M	329_H	0.876	0.96
92_I	331_A	0.867	0.96
275_Y	294_I	0.864	0.96
274_D	293_V	0.863	0.96
156_C	242_V	0.862	0.96
131_V	150_A	0.861	0.96
252_V	257_V	0.859	0.96
21_A	324_V	0.855	0.96
132_M	326_L	0.854	0.96
27_I	328_R	0.849	0.95
46_K	53_R	0.847	0.95
276_S	296_G	0.846	0.95
139_F	143_R	0.845	0.95
107_M	146_I	0.839	0.95
263_R	267_T	0.839	0.95
287_T	317_W	0.839	0.95
239_V	286_N	0.838	0.95
192_H	197_R	0.838	0.95
258_N	294_I	0.838	0.95
50_I	188_I	0.834	0.95
10_F	32_I	0.830	0.95
51_H	286_N	0.827	0.95
34_A	191_P	0.826	0.95
39_E	60_A	0.826	0.95
31_A	88_Y	0.825	0.95
36_Y	41_L	0.823	0.95
60_A	66_I	0.817	0.94
200_A	237_P	0.814	0.94
30_V	90_I	0.810	0.94
160_V	294_I	0.807	0.94
183_N	206_I	0.805	0.94
119_L	126_E	0.803	0.94
102_A	108_G	0.802	0.94
41_L	191_P	0.797	0.94
130_I	139_F	0.797	0.94
102_A	107_M	0.793	0.93
35_S	78_R	0.792	0.93
92_I	330_V	0.790	0.93
181_Y	187_N	0.788	0.93
118_I	326_L	0.782	0.93
132_M	272_V	0.779	0.93
126_E	218_L	0.777	0.93
6_A	112_A	0.772	0.92
3_V	331_A	0.768	0.92
243_D	308_K	0.767	0.92
108_G	111_E	0.766	0.92
186_K	198_A	0.766	0.92
99_K	105_K	0.765	0.92
43_H	47_Y	0.764	0.92
17_V	324_V	0.763	0.92
59_V	66_I	0.758	0.92
137_D	329_H	0.757	0.92
137_D	268_S	0.757	0.92
192_H	198_A	0.755	0.92
50_I	203_E	0.753	0.92
57_E	68_N	0.752	0.91
174_L	230_L	0.750	0.91
263_R	268_S	0.747	0.91
103_K	146_I	0.747	0.91
248_L	301_V	0.746	0.91
38_A	42_A	0.745	0.91
78_R	99_K	0.742	0.91
101_N	105_K	0.742	0.91
45_I	54_Y	0.741	0.91
252_V	307_V	0.740	0.91
195_L	198_A	0.739	0.91
84_P	88_Y	0.736	0.91
175_M	242_V	0.733	0.90
196_R	298_T	0.733	0.90
77_S	83_L	0.730	0.90
75_L	83_L	0.729	0.90
35_S	191_P	0.729	0.90
176_T	245_V	0.727	0.90
256_E	259_E	0.726	0.90
167_E	264_A	0.724	0.90
205_I	310_L	0.723	0.90
42_A	60_A	0.722	0.90
35_S	76_N	0.721	0.90
266_K	270_Y	0.720	0.90
216_L	220_L	0.720	0.90
130_I	143_R	0.720	0.90
50_I	200_A	0.718	0.89
267_T	270_Y	0.715	0.89
46_K	57_E	0.712	0.89
31_A	73_L	0.708	0.89
327_I	330_V	0.707	0.89
150_A	319_Y	0.707	0.89
160_V	242_V	0.706	0.89
32_I	65_L	0.705	0.89
230_L	308_K	0.705	0.89
139_F	329_H	0.703	0.88
181_Y	237_P	0.698	0.88
130_I	138_Q	0.697	0.88
294_I	297_L	0.697	0.88
260_A	264_A	0.696	0.88
183_N	186_K	0.696	0.88
230_L	300_M	0.694	0.88
169_G	249_K	0.692	0.88
262_K	265_A	0.691	0.88
7_I	18_F	0.690	0.88
246_V	307_V	0.688	0.87
131_V	134_V	0.687	0.87
23_L	56_K	0.685	0.87
168_F	250_T	0.683	0.87
58_V	67_V	0.683	0.87
157_L	161_V	0.681	0.87
161_V	227_L	0.681	0.87
246_V	309_V	0.679	0.87
60_A	64_S	0.679	0.87
22_M	68_N	0.678	0.87
149_N	320_S	0.677	0.87
34_A	99_K	0.676	0.86
32_I	74_L	0.673	0.86
119_L	146_I	0.672	0.86
176_T	232_L	0.669	0.86
216_L	227_L	0.667	0.86
139_F	330_V	0.665	0.86
35_S	77_S	0.664	0.85
209_T	214_K	0.664	0.85
63_D	71_K	0.662	0.85
57_E	69_G	0.657	0.85
49_T	237_P	0.656	0.85
62_E	66_I	0.656	0.85
75_L	87_E	0.655	0.85
103_K	145_V	0.654	0.85
15_R	19_R	0.654	0.85
274_D	292_A	0.652	0.84
86_R	112_A	0.652	0.84
174_L	302_M	0.651	0.84
3_V	26_Q	0.651	0.84
245_V	306_K	0.651	0.84
20_K	324_V	0.650	0.84
239_V	242_V	0.650	0.84
263_R	266_K	0.650	0.84
141_A	145_V	0.648	0.84
248_L	257_V	0.642	0.84
4_K	91_D	0.639	0.83
261_F	273_L	0.639	0.83
202_G	237_P	0.638	0.83
142_E	145_V	0.638	0.83
93_V	114_A	0.637	0.83
96_A	327_I	0.636	0.83
36_Y	40_T	0.635	0.83
118_I	330_V	0.634	0.83
24_D	321_C	0.633	0.83
128_V	140_D	0.631	0.82
130_I	326_L	0.631	0.82
211_G	240_S	0.629	0.82
39_E	195_L	0.628	0.82
104_D	111_E	0.626	0.82
43_H	194_D	0.625	0.82
106_A	146_I	0.623	0.82
132_M	149_N	0.622	0.82
45_I	67_V	0.622	0.82
55_D	68_N	0.621	0.81
119_L	127_D	0.621	0.81
167_E	250_T	0.620	0.81
110_I	145_V	0.620	0.81
6_A	88_Y	0.620	0.81
303_E	306_K	0.616	0.81
157_L	242_V	0.614	0.81
45_I	58_V	0.613	0.81
161_V	244_L	0.611	0.80
164_L	244_L	0.609	0.80
195_L	279_P	0.608	0.80
46_K	58_V	0.608	0.80
261_F	309_V	0.606	0.80
5_V	327_I	0.606	0.80
251_D	303_E	0.605	0.80
27_I	92_I	0.602	0.79
101_N	106_A	0.599	0.79
35_S	99_K	0.597	0.79
247_D	306_K	0.596	0.79
6_A	31_A	0.595	0.79
161_V	220_L	0.593	0.78
203_E	286_N	0.592	0.78
258_N	296_G	0.592	0.78
65_L	72_V	0.592	0.78
173_G	246_V	0.592	0.78
43_H	280_L	0.591	0.78
163_V	264_A	0.588	0.78
174_L	228_H	0.586	0.78
18_F	22_M	0.584	0.77
262_K	296_G	0.583	0.77
194_D	208_T	0.580	0.77
91_D	114_A	0.580	0.77
39_E	62_E	0.579	0.77
178_V	205_I	0.578	0.77
29_V	33_N	0.578	0.77
205_I	234_V	0.575	0.76
123_G	127_D	0.574	0.76
156_C	311_A	0.573	0.76
16_M	317_W	0.573	0.76
216_L	228_H	0.572	0.76
30_V	33_N	0.570	0.76
166_E	220_L	0.569	0.76
194_D	198_A	0.568	0.75
3_V	92_I	0.565	0.75
110_I	146_I	0.564	0.75
35_S	41_L	0.564	0.75
181_Y	203_E	0.564	0.75
38_A	63_D	0.564	0.75
85_W	109_H	0.564	0.75
78_R	81_K	0.564	0.75
103_K	108_G	0.564	0.75
132_M	325_D	0.563	0.75
150_A	215_A	0.562	0.75
20_K	317_W	0.561	0.75
175_M	229_G	0.560	0.74
88_Y	112_A	0.559	0.74
205_I	236_V	0.559	0.74
128_V	147_I	0.559	0.74
32_I	72_V	0.559	0.74
168_F	246_V	0.559	0.74
239_V	280_L	0.559	0.74
101_N	124_K	0.559	0.74
323_V	327_I	0.558	0.74
257_V	261_F	0.558	0.74
3_V	6_A	0.557	0.74
261_F	275_Y	0.557	0.74
39_E	43_H	0.556	0.74
5_V	27_I	0.556	0.74
230_L	298_T	0.553	0.73
6_A	89_D	0.549	0.73
246_V	261_F	0.549	0.73
236_V	285_Y	0.549	0.73
181_Y	201_C	0.548	0.73
161_V	246_V	0.547	0.73
86_R	114_A	0.546	0.73
175_M	244_L	0.545	0.72
83_L	109_H	0.544	0.72
20_K	24_D	0.543	0.72
91_D	113_G	0.542	0.72
162_K	268_S	0.541	0.72
167_E	248_L	0.541	0.72
17_V	21_A	0.540	0.72
107_M	145_V	0.540	0.72
173_G	244_L	0.540	0.72
21_A	24_D	0.539	0.72
176_T	308_K	0.538	0.71
109_H	114_A	0.537	0.71
40_T	198_A	0.535	0.71
84_P	112_A	0.535	0.71
177_T	240_S	0.534	0.71
326_L	330_V	0.533	0.71
53_R	278_E	0.533	0.71
47_Y	53_R	0.532	0.71
302_M	306_K	0.531	0.70
167_E	268_S	0.529	0.70
265_A	274_D	0.528	0.70
42_A	65_L	0.527	0.70
8_N	33_N	0.526	0.70
278_E	285_Y	0.525	0.70
149_N	325_D	0.525	0.70
4_K	30_V	0.524	0.69
255_E	258_N	0.524	0.69
184_D	198_A	0.523	0.69
38_A	64_S	0.522	0.69
6_A	75_L	0.522	0.69
320_S	325_D	0.521	0.69
66_I	70_K	0.521	0.69
24_D	325_D	0.519	0.69
319_Y	326_L	0.517	0.68
136_E	268_S	0.517	0.68
60_A	74_L	0.515	0.68
165_D	223_L	0.514	0.68
252_V	305_R	0.513	0.68
176_T	243_D	0.510	0.67
31_A	85_W	0.510	0.67
38_A	61_G	0.509	0.67
40_T	191_P	0.509	0.67
173_G	217_S	0.504	0.67
6_A	85_W	0.504	0.67
300_M	306_K	0.502	0.66
36_Y	76_N	0.501	0.66
20_K	289_P	0.500	0.66

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4boyA	4	0.9824	100	0.209	Contact Map
3idsC	4	0.9971	100	0.221	Contact Map
3docA	4	0.9794	100	0.223	Contact Map
1rm4O	4	0.9794	100	0.226	Contact Map
4lsmA	4	0.9706	100	0.228	Contact Map
2ep7A	4	0.9735	100	0.229	Contact Map
2x5jO	4	0.9618	100	0.229	Contact Map
1obfO	4	0.9706	100	0.238	Contact Map
4o59O	4	0.9706	100	0.238	Contact Map
3cpsA	4	0.9765	100	0.239	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0109 seconds.