GREMLIN Database
YJQC - Uncharacterized protein YjqC
UniProt: O34423 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 278 (262)
Sequences: 622 (235)
Seq/√Len: 14.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
29_L77_I6.1741.00
39_M67_I6.1561.00
10_Y171_D4.4041.00
122_D126_Y3.9981.00
32_Q132_Y3.8871.00
2_F43_L3.4510.99
219_D247_R3.2600.99
58_L220_L3.2080.98
28_V157_V3.1940.98
62_V186_M3.1640.98
58_L87_D2.7690.96
23_K124_E2.6570.95
76_M172_M2.5950.94
43_L63_G2.5070.93
114_S119_M2.4530.92
127_P131_K2.4440.92
158_T177_I2.4340.92
28_V36_I2.4240.92
239_A242_G2.3500.91
15_A167_P2.3050.90
237_G240_F2.1910.87
126_Y131_K2.1170.85
185_N240_F2.0040.82
27_E128_W2.0000.82
50_R82_D1.9830.81
140_L191_I1.9300.79
206_T209_R1.9130.79
58_L62_V1.8910.78
241_D244_G1.8650.77
49_C62_V1.8360.76
92_A100_A1.8280.75
23_K107_N1.8250.75
48_N117_G1.7370.71
248_Y252_P1.7300.71
93_Y103_M1.7190.71
145_A148_N1.7160.71
4_H41_Q1.7070.70
11_Q130_A1.7000.70
80_L169_V1.6880.69
62_V143_F1.6520.67
153_G180_D1.6500.67
180_D187_W1.6460.67
56_K230_S1.6310.66
258_A263_P1.6030.65
165_D170_R1.5950.65
23_K162_A1.5770.64
61_D222_N1.5640.63
38_V187_W1.5590.63
38_V149_A1.4840.59
238_E245_E1.4810.59
29_L73_L1.4700.58
43_L67_I1.4700.58
157_V177_I1.4650.58
218_Y242_G1.4610.58
76_M80_L1.4490.57
68_G74_A1.4390.56
242_G245_E1.3930.54
47_F60_Y1.3720.53
134_I148_N1.3720.53
62_V70_V1.3580.52
6_K61_D1.3470.51
41_Q145_A1.3410.51
99_I105_G1.3160.50
54_K193_E1.3070.49
61_D144_R1.2950.49
164_T172_M1.2950.49
38_V180_D1.2870.48
250_P253_I1.2840.48
147_L229_S1.2710.47
218_Y239_A1.2690.47
39_M176_L1.2660.47
63_G118_A1.2640.47
24_K108_P1.2540.46
60_Y135_S1.2530.46
93_Y104_S1.2510.46
2_F122_D1.2380.45
5_I205_T1.2270.45
74_A100_A1.2180.44
29_L170_R1.2160.44
113_V156_Q1.2130.44
144_R147_L1.2000.43
214_Q217_S1.1880.43
89_Q225_R1.1870.43
29_L157_V1.1860.43
181_T209_R1.1860.43
168_G171_D1.1780.42
264_A268_L1.1680.42
96_N101_A1.1610.41
121_S131_K1.1570.41
46_G196_E1.1540.41
109_Q122_D1.1540.41
39_M49_C1.1500.41
165_D245_E1.1370.40
52_D64_T1.1350.40
135_S142_D1.1280.39
82_D147_L1.1190.39
4_H145_A1.1120.39
74_A83_N1.1100.39
114_S135_S1.0980.38
264_A267_W1.0960.38
114_S117_G1.0900.37
1_M8_L1.0870.37
43_L70_V1.0870.37
148_N162_A1.0750.37
247_R250_P1.0720.37
147_L151_A1.0710.36
55_Y139_L1.0700.36
107_N110_H1.0680.36
100_A263_P1.0590.36
99_I103_M1.0510.35
46_G60_Y1.0500.35
63_G68_G1.0480.35
27_E190_A1.0440.35
17_P81_L1.0440.35
182_Y220_L1.0410.35
68_G268_L1.0390.35
265_P268_L1.0280.34
91_D163_M1.0230.34
123_S152_Q1.0200.34
147_L188_Y1.0190.34
3_Y239_A1.0130.34
132_Y148_N1.0040.33
144_R151_A0.9990.33
29_L36_I0.9930.33
43_L48_N0.9900.32
241_D256_A0.9800.32
122_D185_N0.9790.32
107_N111_A0.9790.32
233_R240_F0.9720.32
130_A162_A0.9710.32
28_V68_G0.9690.31
129_N132_Y0.9570.31
261_L264_A0.9560.31
146_N159_R0.9420.30
6_K102_V0.9400.30
251_A260_H0.9390.30
102_V175_F0.9390.30
14_P76_M0.9390.30
9_Q185_N0.9360.30
219_D249_I0.9280.30
239_A243_R0.9250.29
105_G112_I0.9230.29
114_S122_D0.9230.29
46_G143_F0.9230.29
67_I70_V0.9220.29
190_A223_F0.9190.29
130_A240_F0.9090.29
109_Q151_A0.9090.29
250_P254_A0.9090.29
37_S152_Q0.9080.29
52_D70_V0.9040.28
28_V73_L0.8920.28
76_M166_D0.8890.28
141_A184_Q0.8860.28
98_A106_M0.8850.28
25_L73_L0.8830.27
192_K203_V0.8800.27
236_H260_H0.8800.27
120_A130_A0.8740.27
213_K217_S0.8680.27
109_Q113_V0.8670.27
29_L70_V0.8640.27
171_D174_S0.8610.27
60_Y83_N0.8610.27
20_V106_M0.8600.26
185_N239_A0.8600.26
20_V23_K0.8590.26
48_N118_A0.8580.26
151_A184_Q0.8550.26
249_I252_P0.8550.26
44_F135_S0.8450.26
37_S41_Q0.8440.26
6_K226_G0.8400.26
164_T173_L0.8380.26
249_I253_I0.8360.25
53_A197_R0.8320.25
91_D95_S0.8300.25
17_P239_A0.8290.25
19_P51_A0.8220.25
26_Q29_L0.8200.25
126_Y218_Y0.8190.25
41_Q180_D0.8170.25
191_I216_V0.8120.24
190_A204_P0.8110.24
23_K110_H0.8100.24
60_Y108_P0.8080.24
148_N191_I0.8060.24
40_M135_S0.8050.24
80_L128_W0.8040.24
27_E80_L0.8040.24
60_Y102_V0.7970.24
228_E231_Q0.7940.24
129_N191_I0.7910.24
32_Q148_N0.7880.24
256_A261_L0.7880.24
52_D58_L0.7810.23
16_H132_Y0.7810.23
93_Y98_A0.7800.23
68_G175_F0.7770.23
80_L166_D0.7770.23
218_Y244_G0.7750.23
76_M169_V0.7740.23
2_F64_T0.7730.23
188_Y192_K0.7730.23
82_D229_S0.7720.23
24_K46_G0.7700.23
104_S193_E0.7690.23
98_A215_E0.7670.23
1_M4_H0.7660.23
207_F218_Y0.7640.23
1_M9_Q0.7630.23
48_N114_S0.7580.22
221_F247_R0.7570.22
222_N248_Y0.7570.22
165_D225_R0.7550.22
68_G257_S0.7550.22
233_R236_H0.7530.22
14_P112_I0.7500.22
232_G235_A0.7440.22
107_N261_L0.7430.22
154_R212_E0.7430.22
40_M208_P0.7410.22
48_N63_G0.7380.22
260_H263_P0.7350.21
149_A168_G0.7340.21
133_I143_F0.7330.21
104_S108_P0.7300.21
18_D116_L0.7290.21
182_Y218_Y0.7290.21
17_P82_D0.7280.21
6_K222_N0.7260.21
126_Y129_N0.7240.21
31_G34_G0.7210.21
30_G34_G0.7210.21
51_A100_A0.7210.21
59_L193_E0.7180.21
3_Y122_D0.7160.21
78_S85_P0.7090.21
159_R184_Q0.7090.21
83_N98_A0.7080.20
21_Y126_Y0.7030.20
62_V182_Y0.7030.20
33_F136_S0.7030.20
55_Y193_E0.7020.20
208_P244_G0.7010.20
203_V207_F0.7000.20
255_F266_M0.6970.20
57_D232_G0.6930.20
222_N249_I0.6910.20
14_P223_F0.6890.20
171_D211_L0.6890.20
19_P105_G0.6860.20
21_Y24_K0.6850.20
130_A139_L0.6840.20
26_Q161_Y0.6830.20
118_A208_P0.6820.20
96_N102_V0.6820.20
62_V235_A0.6770.19
74_A207_F0.6730.19
13_K79_R0.6710.19
128_W190_A0.6700.19
76_M113_V0.6690.19
61_D70_V0.6690.19
54_K226_G0.6680.19
52_D63_G0.6660.19
54_K139_L0.6650.19
5_I75_T0.6620.19
145_A185_N0.6620.19
236_H245_E0.6590.19
115_G137_G0.6560.19
19_P86_A0.6530.19
3_Y225_R0.6530.19
29_L153_G0.6530.19
27_E33_F0.6520.19
43_L75_T0.6520.19
77_I143_F0.6510.18
157_V176_L0.6490.18
33_F70_V0.6460.18
79_R170_R0.6460.18
37_S128_W0.6450.18
215_E246_F0.6450.18
136_S141_A0.6430.18
5_I222_N0.6410.18
37_S177_I0.6390.18
23_K122_D0.6370.18
231_Q234_W0.6360.18
79_R261_L0.6340.18
61_D158_T0.6320.18
77_I211_L0.6320.18
31_G35_E0.6290.18
30_G35_E0.6290.18
93_Y191_I0.6260.18
218_Y221_F0.6230.18
77_I256_A0.6230.18
81_L223_F0.6210.18
101_A105_G0.6160.17
93_Y97_P0.6150.17
169_V195_E0.6110.17
159_R172_M0.6090.17
27_E37_S0.6050.17
81_L242_G0.6030.17
122_D125_G0.6020.17
37_S195_E0.6000.17
43_L68_G0.5980.17
15_A176_L0.5980.17
87_D216_V0.5950.17
16_H129_N0.5930.17
151_A249_I0.5920.17
56_K177_I0.5890.17
93_Y100_A0.5890.17
149_A234_W0.5870.16
8_L84_A0.5850.16
29_L62_V0.5850.16
81_L173_L0.5830.16
102_V133_I0.5820.16
154_R177_I0.5810.16
7_E79_R0.5810.16
226_G232_G0.5800.16
92_A97_P0.5790.16
16_H151_A0.5790.16
147_L191_I0.5750.16
27_E132_Y0.5720.16
207_F211_L0.5710.16
42_Y142_D0.5700.16
128_W156_Q0.5690.16
40_M63_G0.5670.16
99_I102_V0.5660.16
97_P104_S0.5660.16
8_L261_L0.5660.16
9_Q256_A0.5660.16
84_A264_A0.5650.16
68_G223_F0.5610.16
38_V178_A0.5600.16
12_A79_R0.5600.16
188_Y266_M0.5600.16
260_H265_P0.5580.16
44_F153_G0.5580.16
49_C139_L0.5570.16
21_Y25_L0.5570.16
217_S239_A0.5560.16
133_I176_L0.5540.15
58_L133_I0.5530.15
211_L214_Q0.5520.15
90_E106_M0.5520.15
98_A260_H0.5510.15
4_H8_L0.5500.15
131_K134_I0.5490.15
106_M188_Y0.5490.15
46_G49_C0.5430.15
227_D250_P0.5410.15
27_E156_Q0.5400.15
165_D260_H0.5400.15
95_S99_I0.5390.15
123_S212_E0.5390.15
136_S154_R0.5370.15
182_Y246_F0.5360.15
54_K101_A0.5360.15
108_P141_A0.5360.15
138_N154_R0.5360.15
29_L99_I0.5350.15
14_P79_R0.5340.15
213_K216_V0.5330.15
130_A206_T0.5320.15
121_S263_P0.5310.15
77_I213_K0.5310.15
140_L152_Q0.5310.15
233_R238_E0.5300.15
100_A104_S0.5300.15
22_A30_G0.5300.15
22_A31_G0.5300.15
119_M133_I0.5300.15
20_V104_S0.5300.15
55_Y184_Q0.5290.15
28_V38_V0.5270.15
206_T264_A0.5260.15
2_F67_I0.5240.15
9_Q184_Q0.5230.15
89_Q110_H0.5230.15
129_N264_A0.5220.15
37_S268_L0.5220.15
82_D264_A0.5210.15
149_A187_W0.5170.14
206_T265_P0.5160.14
130_A134_I0.5150.14
144_R195_E0.5140.14
21_Y189_A0.5110.14
62_V128_W0.5110.14
51_A225_R0.5100.14
126_Y146_N0.5080.14
3_Y7_E0.5070.14
9_Q84_A0.5040.14
152_Q235_A0.5010.14
12_A248_Y0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2v8tA 5 0.9928 100 0.359 Contact Map
1o9iA 6 0.9568 100 0.364 Contact Map
4di0A 2 0.482 98.4 0.918 Contact Map
4cvrA 2 0.5432 98.4 0.918 Contact Map
2fzfA 2 0.5647 98.3 0.919 Contact Map
4tofA 6 0.5468 98.3 0.92 Contact Map
3uoiA 7 0.554 98.2 0.923 Contact Map
3fvbA 6 0.554 98 0.925 Contact Map
3r2kA 6 0.5324 98 0.926 Contact Map
1nfvA 7 0.5827 98 0.926 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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