YFLN - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YFLN - Probable metallo-hydrolase YflN

UniProt:	O34409	Sequences: MSDPYMPLTSVRSGAGFEAAKGVHGLTVQIANVYFIQLPSEPHSFVLIDAGMPQSAGVIVNEAKQRFGEGFQLKAIILTHGHFDHIGAIEEILEHWDVPVYIHSREMPYVTGKEDYPPARPDSKSGLVAKLSPLFPRHSIDISSHVQALPEDGSVPFLDEWMWIATPGHTPGHISLFRDDGRVLVAGDAVITVEQEKMADVLIQKQELHGPPAYFTPDTETAAESILKLAGLEPEALLTGHGIPMTGKNFRSDLTELANRLSSI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	264 (212)
Sequences:	10795 (8422)
Seq/√Len:	578.4

ECOLI - YCBL GLO2 YJCS
BACSU - YFLN YOBT YQJP YYBB YQGX PKSB YTNP YRKH
HALSA - Q9HNJ9 Q9HSH2 Q9HRG5 Q9HQ50 Q9HSD1 Q9HNJ2 Q9HQ42
SULSO - Q97VU0 Q97XZ1 Q97YZ2 Q97UV2 Q97VU4 Q97U88 Q7LYK3 Q97UR2 Q97Y13 Q97WC2 Q97YH8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
166_T	175_S	4.667	1.00
78_L	89_I	3.573	1.00
162_M	179_D	3.571	1.00
44_S	74_K	3.543	1.00
75_A	101_Y	3.207	1.00
77_I	176_L	2.941	1.00
48_I	79_T	2.742	1.00
104_S	150_P	2.648	1.00
182_R	235_E	2.574	1.00
99_P	147_Q	2.519	1.00
178_R	181_G	2.498	1.00
230_A	255_T	2.389	1.00
154_S	160_E	2.346	1.00
18_E	21_K	2.334	1.00
156_P	160_E	2.311	1.00
34_Y	238_L	2.197	1.00
154_S	162_M	2.149	1.00
173_H	187_G	2.098	1.00
46_V	75_A	2.072	1.00
151_E	228_K	2.052	1.00
75_A	99_P	2.041	1.00
218_D	221_T	2.039	1.00
37_Q	45_F	2.038	1.00
34_Y	185_V	1.977	1.00
163_W	174_I	1.975	1.00
163_W	176_L	1.936	1.00
101_Y	147_Q	1.921	1.00
106_E	172_G	1.907	1.00
103_H	174_I	1.880	1.00
150_P	153_G	1.856	1.00
103_H	165_A	1.818	1.00
48_I	185_V	1.799	1.00
161_W	178_R	1.722	1.00
60_V	95_H	1.703	1.00
102_I	106_E	1.682	1.00
45_F	73_L	1.649	1.00
147_Q	153_G	1.555	1.00
107_M	111_T	1.517	1.00
228_K	231_G	1.509	1.00
79_T	176_L	1.479	1.00
177_F	182_R	1.475	1.00
149_L	174_I	1.427	1.00
62_E	65_Q	1.423	1.00
93_L	146_V	1.418	1.00
42_P	159_D	1.395	1.00
46_V	77_I	1.388	1.00
224_E	227_L	1.367	1.00
69_E	72_Q	1.357	1.00
104_S	108_P	1.348	1.00
183_V	238_L	1.345	1.00
76_I	98_V	1.341	1.00
57_G	61_N	1.331	1.00
177_F	184_L	1.331	1.00
186_A	237_L	1.327	1.00
60_V	64_K	1.327	1.00
44_S	75_A	1.304	1.00
166_T	173_H	1.294	1.00
107_M	148_A	1.293	1.00
156_P	159_D	1.277	1.00
79_T	187_G	1.277	1.00
45_F	68_G	1.275	1.00
182_R	233_E	1.272	1.00
48_I	176_L	1.266	1.00
221_T	224_E	1.259	1.00
251_R	255_T	1.232	1.00
50_A	76_I	1.227	1.00
152_D	162_M	1.206	1.00
160_E	180_D	1.199	1.00
227_L	231_G	1.193	1.00
35_F	45_F	1.184	1.00
162_M	177_F	1.177	1.00
104_S	148_A	1.176	1.00
252_S	256_E	1.174	1.00
166_T	225_S	1.167	1.00
253_D	256_E	1.166	1.00
101_Y	149_L	1.164	1.00
76_I	89_I	1.162	1.00
64_K	95_H	1.154	1.00
164_I	177_F	1.149	1.00
162_M	232_L	1.137	1.00
175_S	184_L	1.134	1.00
236_A	246_T	1.131	1.00
177_F	234_P	1.125	1.00
168_G	225_S	1.123	1.00
61_N	64_K	1.123	1.00
45_F	74_K	1.121	1.00
161_W	176_L	1.121	1.00
36_I	48_I	1.117	1.00
50_A	89_I	1.116	1.00
91_E	95_H	1.114	1.00
151_E	165_A	1.110	1.00
247_G	252_S	1.109	1.00
223_A	227_L	1.107	1.00
24_H	37_Q	1.106	1.00
18_E	24_H	1.097	1.00
230_A	251_R	1.082	1.00
58_V	62_E	1.077	1.00
103_H	106_E	1.077	1.00
220_E	224_E	1.059	1.00
106_E	170_T	1.053	1.00
253_D	257_L	1.048	1.00
227_L	230_A	1.044	1.00
22_G	37_Q	1.042	1.00
93_L	100_V	1.024	1.00
154_S	179_D	1.022	1.00
239_T	242_G	1.007	1.00
46_V	157_F	1.002	1.00
46_V	161_W	0.989	1.00
34_Y	240_G	0.989	1.00
183_V	236_A	0.986	1.00
175_S	189_A	0.979	1.00
61_N	65_Q	0.969	1.00
77_I	174_I	0.961	1.00
23_V	178_R	0.948	1.00
24_H	66_R	0.947	1.00
90_E	94_E	0.943	1.00
254_L	257_L	0.942	1.00
44_S	72_Q	0.924	1.00
23_V	36_I	0.923	1.00
184_L	232_L	0.920	1.00
129_A	132_S	0.917	1.00
80_H	188_D	0.917	1.00
143_S	146_V	0.916	1.00
189_A	229_L	0.915	1.00
179_D	182_R	0.908	1.00
105_R	108_P	0.908	1.00
41_E	44_S	0.908	1.00
35_F	47_L	0.907	1.00
233_E	251_R	0.906	1.00
64_K	70_G	0.906	1.00
56_A	88_A	0.900	1.00
36_I	161_W	0.897	1.00
47_L	73_L	0.889	1.00
164_I	175_S	0.889	1.00
85_H	188_D	0.888	1.00
20_A	23_V	0.888	1.00
18_E	22_G	0.884	1.00
58_V	61_N	0.880	1.00
132_S	136_P	0.875	1.00
32_N	242_G	0.867	1.00
76_I	100_V	0.862	1.00
47_L	50_A	0.856	1.00
70_G	96_W	0.852	1.00
167_P	225_S	0.848	1.00
37_Q	68_G	0.843	1.00
251_R	254_L	0.843	1.00
91_E	94_E	0.842	1.00
102_I	107_M	0.840	1.00
45_F	72_Q	0.836	1.00
219_T	223_A	0.825	1.00
175_S	225_S	0.819	1.00
175_S	229_L	0.814	1.00
49_D	80_H	0.813	1.00
37_Q	42_P	0.811	1.00
48_I	77_I	0.806	1.00
149_L	163_W	0.804	1.00
185_V	238_L	0.802	1.00
20_A	181_G	0.797	1.00
22_G	181_G	0.795	1.00
168_G	173_H	0.794	1.00
64_K	69_E	0.793	1.00
32_N	240_G	0.792	1.00
130_K	133_P	0.788	1.00
186_A	239_T	0.787	1.00
78_L	86_I	0.783	1.00
37_Q	71_F	0.780	1.00
35_F	63_A	0.779	1.00
216_T	222_A	0.779	1.00
250_F	254_L	0.775	1.00
102_I	110_V	0.771	1.00
160_E	179_D	0.771	1.00
234_P	237_L	0.766	1.00
224_E	228_K	0.763	1.00
129_A	133_P	0.761	1.00
178_R	185_V	0.759	1.00
67_F	70_G	0.757	1.00
252_S	255_T	0.754	1.00
133_P	136_P	0.754	1.00
177_F	232_L	0.751	1.00
212_P	215_F	0.751	1.00
19_A	238_L	0.750	1.00
33_V	47_L	0.746	1.00
33_V	51_G	0.743	1.00
164_I	228_K	0.738	1.00
178_R	183_V	0.737	1.00
37_Q	66_R	0.735	1.00
74_K	99_P	0.732	1.00
187_G	240_G	0.730	1.00
84_D	241_H	0.728	1.00
108_P	112_G	0.725	1.00
93_L	97_D	0.724	1.00
33_V	59_I	0.721	1.00
238_L	244_P	0.720	1.00
217_P	220_E	0.720	1.00
82_H	85_H	0.719	1.00
60_V	70_G	0.718	1.00
250_F	253_D	0.716	1.00
108_P	111_T	0.715	1.00
142_I	145_H	0.715	1.00
170_T	173_H	0.707	1.00
62_E	66_R	0.705	1.00
25_G	238_L	0.703	1.00
75_A	147_Q	0.702	1.00
99_P	146_V	0.702	1.00
132_S	135_F	0.702	1.00
248_K	252_S	0.696	1.00
247_G	250_F	0.694	1.00
213_A	216_T	0.690	1.00
237_L	245_M	0.685	1.00
81_G	106_E	0.685	1.00
109_Y	171_P	0.680	1.00
76_I	92_I	0.677	1.00
184_L	237_L	0.676	1.00
115_D	118_P	0.671	1.00
80_H	85_H	0.670	1.00
222_A	226_I	0.669	1.00
56_A	91_E	0.666	1.00
88_A	91_E	0.664	1.00
41_E	46_V	0.661	1.00
23_V	185_V	0.655	1.00
218_D	222_A	0.655	1.00
50_A	88_A	0.655	1.00
149_L	153_G	0.654	1.00
20_A	235_E	0.654	1.00
106_E	109_Y	0.654	1.00
165_A	174_I	0.653	1.00
208_L	211_P	0.650	1.00
86_I	110_V	0.647	1.00
82_H	170_T	0.646	1.00
23_V	183_V	0.645	1.00
166_T	189_A	0.642	1.00
41_E	159_D	0.639	1.00
105_R	165_A	0.638	1.00
89_I	100_V	0.636	1.00
245_M	253_D	0.634	1.00
53_P	87_G	0.628	1.00
186_A	190_V	0.627	1.00
215_F	218_D	0.627	1.00
192_T	245_M	0.627	1.00
184_L	234_P	0.622	1.00
68_G	72_Q	0.620	1.00
19_A	23_V	0.617	1.00
92_I	96_W	0.616	1.00
73_L	96_W	0.616	1.00
225_S	228_K	0.616	1.00
25_G	34_Y	0.612	1.00
63_A	68_G	0.612	1.00
35_F	73_L	0.611	1.00
47_L	92_I	0.611	1.00
114_E	117_P	0.610	1.00
57_G	60_V	0.609	1.00
164_I	232_L	0.607	1.00
43_H	158_L	0.606	1.00
20_A	29_Q	0.603	1.00
189_A	225_S	0.603	1.00
20_A	236_A	0.603	1.00
169_H	188_D	0.603	1.00
173_H	240_G	0.602	1.00
46_V	158_L	0.602	1.00
189_A	222_A	0.600	1.00
43_H	74_K	0.598	1.00
33_V	50_A	0.595	1.00
90_E	93_L	0.594	1.00
49_D	188_D	0.594	1.00
81_G	102_I	0.592	1.00
109_Y	114_E	0.591	1.00
81_G	86_I	0.590	1.00
104_S	107_M	0.588	1.00
81_G	172_G	0.587	1.00
25_G	28_V	0.586	1.00
192_T	243_I	0.585	1.00
45_F	69_E	0.585	1.00
37_Q	41_E	0.581	1.00
227_L	255_T	0.579	1.00
191_I	242_G	0.579	1.00
36_I	178_R	0.576	1.00
248_K	251_R	0.574	1.00
106_E	165_A	0.570	1.00
79_T	82_H	0.567	0.99
63_A	66_R	0.565	0.99
60_V	96_W	0.565	0.99
80_H	84_D	0.564	0.99
49_D	85_H	0.563	0.99
211_P	222_A	0.561	0.99
161_W	185_V	0.559	0.99
67_F	72_Q	0.556	0.99
23_V	27_T	0.552	0.99
47_L	63_A	0.550	0.99
233_E	236_A	0.547	0.99
86_I	89_I	0.542	0.99
109_Y	113_K	0.542	0.99
53_P	88_A	0.540	0.99
101_Y	153_G	0.539	0.99
111_T	144_S	0.536	0.99
153_G	163_W	0.533	0.99
239_T	245_M	0.530	0.99
112_G	115_D	0.528	0.99
105_R	171_P	0.527	0.99
107_M	146_V	0.527	0.99
50_A	78_L	0.527	0.99
20_A	24_H	0.525	0.99
19_A	25_G	0.524	0.99
82_H	168_G	0.524	0.99
220_E	223_A	0.523	0.99
150_P	165_A	0.521	0.99
85_H	241_H	0.519	0.99
106_E	110_V	0.517	0.99
20_A	27_T	0.513	0.99
149_L	176_L	0.512	0.99
45_F	63_A	0.510	0.99
107_M	110_V	0.510	0.99
166_T	187_G	0.508	0.99
212_P	217_P	0.508	0.99
25_G	29_Q	0.506	0.99
57_G	91_E	0.505	0.99
73_L	98_V	0.501	0.99
22_G	25_G	0.501	0.99
18_E	66_R	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2zo4A	1	0.8598	100	0.333	Contact Map
2fhxA	2	0.8826	100	0.374	Contact Map
2yheA	3	0.9432	100	0.378	Contact Map
3vpeA	1	0.8902	100	0.379	Contact Map
2cfuA	2	0.9318	100	0.381	Contact Map
2vw8A	2	0.9129	100	0.382	Contact Map
4nurA	2	0.9432	100	0.384	Contact Map
4pdxA	2	0.9242	100	0.387	Contact Map
1k07A	1	0.8712	100	0.395	Contact Map
3q6vA	1	0.8182	100	0.398	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.009 seconds.