GREMLIN Database
LIGD - Bifunctional non-homologous end joining protein LigD
UniProt: O34398 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 611 (571)
Sequences: 878 (588)
Seq/√Len: 24.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
259_M273_L8.4061.00
344_F546_T6.2821.00
556_A577_V5.6651.00
21_Y188_A5.2401.00
50_S57_T5.0211.00
562_E580_R4.9711.00
218_T230_S4.8141.00
503_A529_L4.7651.00
369_Y377_S4.4831.00
179_I209_N4.3201.00
443_P446_D4.0471.00
264_H274_E3.9121.00
222_P271_F3.8721.00
188_A205_L3.7631.00
283_Y286_I3.6221.00
284_L294_V3.5691.00
32_L41_L3.5131.00
279_A299_F3.4871.00
491_T494_E3.4541.00
8_V202_S3.2901.00
32_L60_A3.1501.00
431_R536_E3.1391.00
30_C41_L3.1231.00
256_R260_E3.0451.00
138_K166_P3.0091.00
10_T205_L2.9851.00
217_I279_A2.8921.00
81_C114_C2.8691.00
263_G271_F2.8461.00
127_E140_S2.8451.00
500_Q504_E2.8240.99
223_N226_F2.8070.99
471_P479_I2.7540.99
419_L546_T2.6970.99
75_L118_A2.6830.99
284_L293_E2.6360.99
217_I299_F2.6340.99
23_V183_G2.4760.99
519_L522_N2.4360.98
157_Y166_P2.3760.98
212_Q280_A2.3590.98
438_I502_I2.3480.98
20_R191_T2.3280.98
231_V240_I2.3060.98
459_K463_D2.2340.97
226_F242_S2.1760.97
245_H295_S2.1430.96
30_C79_I2.1400.96
553_T570_A2.1350.96
590_D594_N2.1200.96
342_E346_Q2.0720.96
347_Y577_V2.0480.95
546_T574_I2.0470.95
381_K537_G2.0220.95
178_V183_G2.0210.95
558_L563_V2.0180.95
216_C237_M2.0120.95
352_S356_L1.9780.94
348_M546_T1.9670.94
5_M193_S1.9490.94
429_K487_P1.9330.94
214_Y303_M1.9280.94
404_C409_T1.9230.93
473_L555_A1.9170.93
176_E180_K1.9140.93
506_C529_L1.9100.93
291_L294_V1.8800.93
254_A258_I1.8770.93
223_N252_K1.8740.93
188_A207_Y1.8630.92
577_V581_I1.8450.92
220_F256_R1.8420.92
79_I114_C1.8250.91
573_T576_T1.8060.91
556_A580_R1.8060.91
357_P586_C1.8040.91
220_F271_F1.8040.91
438_I458_L1.7990.91
262_H276_S1.7990.91
142_R165_I1.7960.91
455_A479_I1.7920.91
472_K555_A1.7830.91
543_P555_A1.7760.90
214_Y300_E1.7730.90
455_A560_W1.7240.89
75_L116_F1.7160.89
82_L88_A1.7140.89
365_T379_F1.6990.88
132_L136_D1.6920.88
460_R464_S1.6810.88
496_R532_L1.6610.87
518_R528_Y1.6480.87
450_M453_Q1.6450.86
326_F419_L1.6450.86
83_V87_R1.6270.86
541_I545_S1.6210.86
258_I262_H1.6130.85
228_T270_E1.6060.85
329_L342_E1.6040.85
135_L191_T1.5900.85
364_V413_L1.5810.84
218_T228_T1.5680.84
497_Q500_Q1.5610.83
231_V286_I1.5610.83
91_E223_N1.5550.83
515_T518_R1.5420.83
35_H72_P1.5360.82
452_V566_S1.5320.82
34_I60_A1.5300.82
243_V379_F1.5230.82
4_T198_K1.5140.81
468_T596_Q1.4970.81
358_F435_E1.4960.81
355_L421_F1.4790.80
300_E303_M1.4740.80
473_L479_I1.4730.80
335_E373_S1.4720.80
415_N533_Q1.4710.80
216_C308_C1.4640.79
121_L144_L1.4630.79
286_I479_I1.4600.79
436_I495_T1.4570.79
220_F263_G1.4560.79
403_V428_I1.4480.78
469_S483_I1.4400.78
339_K343_D1.4360.78
314_I317_S1.4290.77
132_L140_S1.4090.76
454_A514_F1.4050.76
138_K171_F1.3990.76
474_S540_I1.3990.76
392_Q405_E1.3520.73
541_I555_A1.3510.73
127_E132_L1.3460.73
422_H541_I1.3430.73
405_E409_T1.3420.73
258_I301_F1.3400.73
191_T526_K1.3380.73
218_T242_S1.3350.72
456_N564_Q1.3310.72
351_V581_I1.3270.72
228_T239_P1.3260.72
334_F552_G1.3250.72
248_R251_E1.3230.72
559_Y584_Q1.3230.72
219_G244_S1.3110.71
332_I340_T1.3050.71
59_F353_D1.3010.70
398_S526_K1.2990.70
193_S203_D1.2940.70
437_V536_E1.2900.70
30_C53_F1.2870.70
365_T424_P1.2860.70
18_E192_N1.2780.69
472_K543_P1.2770.69
15_I172_D1.2700.69
33_R74_T1.2660.68
326_F333_I1.2630.68
118_A121_L1.2620.68
457_E510_F1.2610.68
285_T294_V1.2530.67
214_Y302_Q1.2510.67
58_Q61_K1.2490.67
558_L569_P1.2490.67
326_F329_L1.2490.67
34_I238_T1.2400.67
176_E526_K1.2380.67
30_C116_F1.2310.66
457_E514_F1.2300.66
459_K560_W1.2210.65
356_L406_D1.2200.65
425_F540_I1.2130.65
471_P563_V1.2130.65
213_A311_A1.2110.65
311_A485_L1.2090.65
392_Q406_D1.2050.64
368_R380_Q1.2040.64
339_K574_I1.2000.64
334_F344_F1.1970.64
449_L452_V1.1960.64
32_L116_F1.1880.63
52_T280_A1.1870.63
196_L199_K1.1830.63
262_H277_I1.1800.63
77_G116_F1.1770.62
348_M414_C1.1740.62
457_E461_L1.1740.62
53_F79_I1.1740.62
213_A283_Y1.1620.61
373_S377_S1.1610.61
518_R535_A1.1560.61
277_I299_F1.1530.61
186_I283_Y1.1510.61
164_S167_C1.1480.61
427_T434_A1.1460.60
473_L556_A1.1450.60
446_D515_T1.1410.60
266_T274_E1.1400.60
260_E263_G1.1390.60
355_L414_C1.1390.60
540_I555_A1.1380.60
470_Y594_N1.1290.59
126_G351_V1.1240.59
365_T401_H1.1240.59
278_C308_C1.1170.58
115_C156_P1.1150.58
135_L192_N1.1080.58
461_L509_A1.1040.57
558_L566_S1.0980.57
229_V247_M1.0980.57
172_D176_E1.0920.57
355_L584_Q1.0900.56
463_D468_T1.0880.56
253_S257_E1.0860.56
142_R146_S1.0850.56
190_K203_D1.0750.55
476_N549_N1.0740.55
307_E512_E1.0730.55
423_V542_C1.0710.55
367_I548_G1.0700.55
250_E573_T1.0670.55
33_R42_T1.0630.55
13_P293_E1.0620.54
242_S295_S1.0610.54
588_F591_F1.0590.54
216_C230_S1.0570.54
515_T522_N1.0560.54
461_L506_C1.0530.54
402_I413_L1.0530.54
71_L125_S1.0490.54
251_E254_A1.0490.54
273_L421_F1.0470.53
74_T460_R1.0430.53
251_E296_F1.0420.53
310_Y314_I1.0400.53
474_S555_A1.0390.53
20_R186_I1.0370.53
334_F337_N1.0340.52
382_N399_H1.0310.52
350_E578_I1.0300.52
213_A231_V1.0290.52
556_A562_E1.0220.52
215_V229_V1.0220.52
333_I474_S1.0160.51
167_C334_F1.0160.51
91_E95_V1.0160.51
60_A118_A1.0150.51
136_D139_K1.0110.51
533_Q540_I1.0090.51
139_K143_E1.0060.50
82_L117_L1.0050.50
326_F331_K1.0020.50
116_F221_N1.0000.50
327_T541_I0.9940.50
474_S522_N0.9940.50
458_L506_C0.9920.49
6_Q44_R0.9910.49
352_S407_M0.9890.49
382_N533_Q0.9870.49
231_V311_A0.9850.49
170_H173_Q0.9770.48
5_M327_T0.9760.48
221_N228_T0.9750.48
311_A315_R0.9730.48
15_I186_I0.9670.48
474_S483_I0.9670.48
124_R129_V0.9650.48
40_T529_L0.9640.47
305_W437_V0.9570.47
210_F293_E0.9560.47
13_P383_K0.9530.47
331_K566_S0.9510.47
192_N250_E0.9450.46
203_D273_L0.9420.46
70_E73_L0.9420.46
21_Y207_Y0.9420.46
369_Y425_F0.9410.46
49_L533_Q0.9410.46
214_Y219_G0.9400.46
271_F279_A0.9320.45
355_L410_L0.9310.45
98_R543_P0.9300.45
469_S596_Q0.9300.45
335_E374_R0.9300.45
133_S352_S0.9280.45
242_S290_T0.9270.45
344_F419_L0.9250.45
87_R182_D0.9240.45
381_K474_S0.9230.45
25_Y43_S0.9210.44
426_Q492_Y0.9190.44
9_L285_T0.9160.44
546_T554_V0.9150.44
533_Q588_F0.9150.44
285_T293_E0.9150.44
434_A487_P0.9120.44
216_C305_W0.9090.44
351_V376_E0.9070.43
73_L165_I0.9060.43
361_N428_I0.9040.43
135_L138_K0.9020.43
333_I344_F0.9010.43
32_L220_F0.9000.43
369_Y540_I0.8970.43
38_G236_I0.8950.43
138_K157_Y0.8910.42
187_V541_I0.8900.42
382_N415_N0.8880.42
413_L421_F0.8880.42
528_Y533_Q0.8880.42
214_Y244_S0.8870.42
415_N492_Y0.8840.42
333_I556_A0.8780.41
229_V291_L0.8780.41
424_P480_Q0.8780.41
126_G485_L0.8770.41
486_S596_Q0.8750.41
14_P514_F0.8730.41
228_T242_S0.8720.41
88_A183_G0.8690.41
60_A474_S0.8680.41
493_E535_A0.8670.41
578_I582_K0.8670.41
324_L411_L0.8650.40
418_A422_H0.8630.40
282_Q297_I0.8570.40
148_A151_P0.8570.40
467_I476_N0.8560.40
265_Q340_T0.8550.40
216_C433_P0.8540.40
218_T232_L0.8540.40
43_S383_K0.8520.40
89_D92_H0.8520.40
591_F594_N0.8520.40
187_V447_D0.8520.40
255_I259_M0.8500.39
395_Y431_R0.8450.39
40_T48_E0.8450.39
318_K321_H0.8400.39
420_E437_V0.8380.39
242_S269_G0.8380.39
73_L124_R0.8370.39
118_A328_S0.8350.38
81_C92_H0.8330.38
554_V572_F0.8320.38
133_S203_D0.8320.38
18_E186_I0.8310.38
30_C588_F0.8310.38
61_K431_R0.8290.38
492_Y538_K0.8290.38
311_A314_I0.8260.38
391_V411_L0.8260.38
233_K238_T0.8240.38
460_R463_D0.8240.38
201_S359_L0.8240.38
271_F391_V0.8220.37
242_S425_F0.8220.37
568_T571_L0.8200.37
57_T429_K0.8190.37
136_D429_K0.8190.37
242_S293_E0.8180.37
66_H276_S0.8160.37
396_D401_H0.8160.37
380_Q532_L0.8140.37
459_K469_S0.8140.37
515_T520_I0.8130.37
10_T213_A0.8120.37
347_Y482_Y0.8120.37
361_N405_E0.8100.37
30_C57_T0.8090.37
347_Y351_V0.8090.37
116_F146_S0.8090.37
561_H564_Q0.8080.37
358_F544_Y0.8070.36
34_I451_A0.8070.36
255_I299_F0.8060.36
238_T550_E0.8050.36
243_V281_V0.8030.36
279_A296_F0.8020.36
375_S550_E0.7990.36
455_A459_K0.7980.36
436_I531_Y0.7980.36
328_S331_K0.7980.36
404_C410_L0.7950.36
87_R334_F0.7930.36
244_S247_M0.7930.36
463_D469_S0.7920.35
117_L351_V0.7890.35
391_V409_T0.7890.35
20_R138_K0.7870.35
359_L461_L0.7860.35
452_V567_L0.7860.35
7_P338_K0.7840.35
191_T554_V0.7830.35
343_D346_Q0.7830.35
193_S196_L0.7820.35
223_N271_F0.7810.35
422_H477_K0.7800.35
592_Y596_Q0.7790.35
485_L499_T0.7770.35
229_V286_I0.7740.34
533_Q538_K0.7730.34
425_F520_I0.7730.34
110_N113_P0.7700.34
468_T526_K0.7700.34
330_D449_L0.7690.34
516_T529_L0.7670.34
471_P588_F0.7660.34
312_Q317_S0.7660.34
196_L201_S0.7660.34
415_N538_K0.7610.33
178_V221_N0.7610.33
325_Q328_S0.7590.33
229_V243_V0.7580.33
121_L140_S0.7560.33
13_P207_Y0.7550.33
312_Q318_K0.7550.33
358_F543_P0.7540.33
364_V574_I0.7540.33
139_K497_Q0.7530.33
345_I415_N0.7510.33
476_N533_Q0.7500.33
49_L476_N0.7490.33
133_S136_D0.7490.33
230_S287_L0.7450.32
225_G259_M0.7440.32
590_D593_R0.7440.32
531_Y578_I0.7440.32
30_C598_E0.7430.32
337_N552_G0.7430.32
14_P476_N0.7430.32
3_F537_G0.7420.32
298_G344_F0.7420.32
316_H437_V0.7410.32
225_G479_I0.7380.32
273_L286_I0.7370.32
310_Y313_V0.7370.32
247_M252_K0.7350.32
317_S321_H0.7340.32
519_L572_F0.7320.32
279_A347_Y0.7320.32
458_L481_L0.7320.32
325_Q577_V0.7310.32
217_I263_G0.7310.32
212_Q305_W0.7310.32
448_F452_V0.7300.32
365_T502_I0.7290.31
477_K520_I0.7280.31
34_I70_E0.7280.31
333_I522_N0.7280.31
367_I477_K0.7270.31
401_H535_A0.7270.31
315_R319_P0.7270.31
49_L415_N0.7260.31
5_M533_Q0.7220.31
112_R294_V0.7220.31
25_Y293_E0.7210.31
399_H418_A0.7210.31
367_I422_H0.7210.31
285_T436_I0.7190.31
215_V331_K0.7180.31
476_N514_F0.7180.31
250_E274_E0.7160.31
382_N476_N0.7150.31
544_Y586_C0.7140.31
166_P171_F0.7140.31
289_G293_E0.7140.31
178_V473_L0.7120.30
368_R420_E0.7110.30
173_Q177_M0.7110.30
255_I271_F0.7100.30
116_F406_D0.7100.30
403_V409_T0.7090.30
327_T393_S0.7080.30
552_G572_F0.7080.30
40_T288_Q0.7060.30
24_K27_G0.7060.30
444_S528_Y0.7050.30
344_F414_C0.7050.30
443_P515_T0.7040.30
217_I259_M0.7040.30
410_L421_F0.7030.30
18_E203_D0.7020.30
391_V402_I0.7020.30
23_V165_I0.7010.30
563_V567_L0.7010.30
524_H552_G0.7000.30
4_T8_V0.7000.30
3_F199_K0.7000.30
147_A360_K0.6990.30
283_Y433_P0.6980.30
214_Y308_C0.6980.30
187_V574_I0.6980.30
305_W308_C0.6980.30
213_A286_I0.6970.30
3_F198_K0.6960.29
30_C465_F0.6950.29
367_I514_F0.6940.29
257_E260_E0.6920.29
225_G256_R0.6910.29
164_S281_V0.6900.29
349_I407_M0.6880.29
326_F411_L0.6880.29
482_Y533_Q0.6880.29
224_N259_M0.6860.29
232_L236_I0.6840.29
363_A532_L0.6840.29
270_E294_V0.6830.29
558_L565_S0.6820.29
49_L422_H0.6810.29
175_W207_Y0.6810.29
26_D29_R0.6810.29
24_K29_R0.6810.29
382_N514_F0.6810.29
71_L75_L0.6810.29
335_E355_L0.6760.28
213_A308_C0.6760.28
22_E26_D0.6750.28
125_S367_I0.6740.28
41_L361_N0.6740.28
520_I524_H0.6740.28
417_L544_Y0.6730.28
14_P19_W0.6730.28
138_K377_S0.6730.28
18_E143_E0.6730.28
9_L213_A0.6720.28
324_L578_I0.6720.28
15_I432_R0.6710.28
114_C228_T0.6700.28
425_F471_P0.6700.28
216_C231_V0.6690.28
225_G413_L0.6680.28
96_R114_C0.6680.28
217_I273_L0.6670.28
18_E190_K0.6670.28
245_H279_A0.6670.28
273_L536_E0.6650.28
373_S419_L0.6650.28
176_E234_N0.6640.28
93_L241_A0.6630.28
149_K437_V0.6620.27
55_E71_L0.6620.27
587_P591_F0.6610.27
143_E250_E0.6610.27
40_T255_I0.6600.27
54_P58_Q0.6590.27
12_S469_S0.6570.27
173_Q201_S0.6560.27
130_T198_K0.6530.27
87_R170_H0.6520.27
260_E563_V0.6520.27
402_I455_A0.6520.27
310_Y315_R0.6510.27
309_T361_N0.6500.27
118_A145_I0.6500.27
382_N548_G0.6500.27
35_H38_G0.6490.27
496_R500_Q0.6490.27
234_N570_A0.6490.27
217_I512_E0.6480.27
136_D144_L0.6460.27
483_I528_Y0.6450.26
398_S401_H0.6450.26
425_F435_E0.6440.26
423_V541_I0.6430.26
493_E497_Q0.6430.26
332_I338_K0.6430.26
518_R533_Q0.6420.26
209_N531_Y0.6420.26
13_P285_T0.6410.26
563_V566_S0.6410.26
459_K474_S0.6410.26
253_S487_P0.6400.26
146_S151_P0.6390.26
61_K263_G0.6390.26
49_L540_I0.6370.26
373_S474_S0.6350.26
39_V279_A0.6350.26
49_L492_Y0.6340.26
387_A391_V0.6330.26
242_S586_C0.6320.26
53_F97_G0.6310.26
18_E273_L0.6310.26
138_K175_W0.6310.26
519_L552_G0.6300.26
72_P555_A0.6290.26
403_V554_V0.6290.26
361_N573_T0.6270.25
6_Q200_R0.6260.25
140_S143_E0.6250.25
170_H187_V0.6250.25
210_F284_L0.6250.25
411_L508_N0.6230.25
35_H40_T0.6230.25
193_S543_P0.6230.25
269_G345_I0.6210.25
170_H389_D0.6210.25
20_R139_K0.6210.25
97_G352_S0.6210.25
14_P587_P0.6200.25
259_M284_L0.6180.25
331_K371_H0.6170.25
418_A506_C0.6170.25
73_L186_I0.6170.25
502_I559_Y0.6170.25
415_N588_F0.6160.25
261_Q332_I0.6150.25
214_Y280_A0.6140.25
347_Y452_V0.6140.25
56_I469_S0.6140.25
247_M279_A0.6130.25
236_I573_T0.6120.25
354_Y585_G0.6110.25
520_I543_P0.6110.25
193_S308_C0.6110.25
223_N268_S0.6080.24
118_A412_W0.6070.24
352_S466_G0.6070.24
176_E544_Y0.6060.24
113_P427_T0.6060.24
558_L576_T0.6050.24
229_V537_G0.6040.24
342_E408_S0.6040.24
317_S323_K0.6040.24
452_V563_V0.6030.24
329_L476_N0.6030.24
60_A343_D0.6020.24
494_E598_E0.6010.24
499_T544_Y0.6010.24
125_S267_P0.6010.24
226_F487_P0.6010.24
36_S350_E0.6010.24
110_N132_L0.6000.24
203_D364_V0.6000.24
231_V283_Y0.5990.24
471_P587_P0.5990.24
345_I414_C0.5980.24
449_L566_S0.5960.24
293_E297_I0.5960.24
232_L250_E0.5950.24
397_G401_H0.5950.24
414_C546_T0.5940.24
569_P576_T0.5930.24
239_P242_S0.5930.24
471_P531_Y0.5930.24
368_R378_F0.5930.24
518_R540_I0.5930.24
142_R157_Y0.5920.24
40_T180_K0.5920.24
66_H374_R0.5920.24
156_P400_E0.5910.24
22_E27_G0.5910.24
58_Q361_N0.5910.24
214_Y278_C0.5900.24
245_H288_Q0.5890.23
30_C471_P0.5890.23
35_H306_T0.5880.23
238_T436_I0.5880.23
415_N518_R0.5880.23
421_F514_F0.5870.23
313_V321_H0.5870.23
492_Y533_Q0.5870.23
345_I492_Y0.5860.23
240_I286_I0.5850.23
371_H404_C0.5850.23
334_F567_L0.5840.23
144_L147_A0.5830.23
388_P412_W0.5830.23
553_T573_T0.5830.23
336_K374_R0.5830.23
444_S447_D0.5820.23
143_E274_E0.5820.23
297_I379_F0.5820.23
145_I437_V0.5810.23
156_P183_G0.5810.23
517_E522_N0.5810.23
61_K502_I0.5810.23
237_M277_I0.5800.23
213_A296_F0.5800.23
481_L515_T0.5800.23
59_F553_T0.5800.23
393_S405_E0.5790.23
404_C567_L0.5770.23
188_A388_P0.5760.23
343_D575_D0.5760.23
331_K448_F0.5760.23
130_T199_K0.5750.23
9_L414_C0.5750.23
116_F500_Q0.5740.23
329_L422_H0.5730.23
22_E29_R0.5730.23
30_C367_I0.5720.23
448_F451_A0.5720.23
171_F346_Q0.5720.23
413_L418_A0.5680.22
73_L151_P0.5680.22
72_P187_V0.5680.22
359_L453_Q0.5670.22
267_P272_T0.5670.22
418_A474_S0.5660.22
72_P125_S0.5660.22
58_Q149_K0.5660.22
417_L518_R0.5650.22
51_S502_I0.5640.22
171_F175_W0.5640.22
510_F543_P0.5640.22
126_G484_P0.5630.22
544_Y556_A0.5630.22
412_W416_Q0.5630.22
510_F555_A0.5620.22
329_L438_I0.5620.22
306_T524_H0.5620.22
228_T303_M0.5610.22
30_C505_Y0.5600.22
9_L212_Q0.5600.22
39_V86_C0.5590.22
260_E309_T0.5590.22
412_W533_Q0.5580.22
419_L562_E0.5560.22
542_C567_L0.5560.22
60_A473_L0.5560.22
333_I572_F0.5560.22
118_A122_L0.5540.22
522_N552_G0.5540.22
379_F589_F0.5540.22
66_H307_E0.5540.22
425_F533_Q0.5530.22
580_R587_P0.5520.22
54_P57_T0.5520.22
399_H563_V0.5510.22
131_L309_T0.5510.22
321_H330_D0.5510.22
198_K504_E0.5510.22
70_E448_F0.5500.22
59_F151_P0.5490.21
231_V472_K0.5490.21
343_D546_T0.5490.21
350_E561_H0.5480.21
145_I402_I0.5480.21
244_S303_M0.5480.21
461_L505_Y0.5470.21
382_N454_A0.5470.21
122_L132_L0.5470.21
285_T288_Q0.5470.21
30_C54_P0.5460.21
334_F553_T0.5460.21
34_I39_V0.5450.21
45_N493_E0.5450.21
426_Q521_K0.5450.21
198_K408_S0.5440.21
415_N482_Y0.5420.21
97_G409_T0.5420.21
573_T581_I0.5420.21
187_V294_V0.5420.21
9_L529_L0.5410.21
211_K265_Q0.5410.21
429_K488_E0.5410.21
390_F533_Q0.5400.21
435_E507_T0.5400.21
245_H424_P0.5400.21
435_E514_F0.5390.21
326_F345_I0.5390.21
39_V554_V0.5390.21
79_I412_W0.5390.21
138_K569_P0.5370.21
425_F531_Y0.5370.21
435_E533_Q0.5360.21
333_I438_I0.5360.21
436_I499_T0.5360.21
358_F472_K0.5360.21
302_Q551_L0.5360.21
138_K205_L0.5350.21
474_S585_G0.5340.21
110_N281_V0.5340.21
209_N212_Q0.5330.21
437_V593_R0.5330.21
60_A222_P0.5330.21
80_V281_V0.5320.21
126_G327_T0.5320.21
132_L419_L0.5310.21
254_A361_N0.5310.21
56_I59_F0.5310.21
422_H467_I0.5310.21
471_P566_S0.5300.21
174_L192_N0.5300.21
74_T122_L0.5300.21
75_L352_S0.5300.21
41_L543_P0.5290.21
92_H95_V0.5290.21
131_L196_L0.5280.20
88_A222_P0.5280.20
122_L450_M0.5280.20
488_E597_D0.5280.20
346_Q349_I0.5280.20
429_K469_S0.5270.20
295_S505_Y0.5270.20
20_R135_L0.5260.20
473_L576_T0.5250.20
96_R367_I0.5250.20
20_R134_Y0.5250.20
287_L298_G0.5250.20
291_L334_F0.5250.20
334_F452_V0.5250.20
280_A300_E0.5250.20
473_L566_S0.5250.20
233_K262_H0.5240.20
392_Q565_S0.5230.20
165_I424_P0.5230.20
180_K264_H0.5230.20
329_L587_P0.5230.20
374_R574_I0.5230.20
518_R521_K0.5230.20
352_S506_C0.5220.20
385_D535_A0.5220.20
453_Q513_L0.5220.20
138_K540_I0.5220.20
427_T493_E0.5210.20
462_L481_L0.5210.20
313_V316_H0.5200.20
397_G561_H0.5190.20
422_H506_C0.5190.20
13_P481_L0.5180.20
85_P121_L0.5180.20
218_T526_K0.5180.20
494_E554_V0.5180.20
357_P544_Y0.5170.20
355_L577_V0.5160.20
59_F220_F0.5150.20
73_L121_L0.5150.20
544_Y585_G0.5130.20
178_V581_I0.5120.20
191_T402_I0.5120.20
331_K365_T0.5120.20
554_V577_V0.5120.20
286_I472_K0.5110.20
488_E558_L0.5090.20
223_N556_A0.5060.19
142_R150_L0.5060.19
281_V504_E0.5060.19
226_F252_K0.5050.19
239_P290_T0.5050.19
272_T363_A0.5050.19
429_K508_N0.5040.19
495_T503_A0.5040.19
223_N247_M0.5040.19
345_I466_G0.5040.19
323_K353_D0.5030.19
276_S515_T0.5030.19
45_N229_V0.5030.19
84_N321_H0.5020.19
218_T229_V0.5020.19
212_Q298_G0.5010.19
194_K253_S0.5000.19
124_R448_F0.5000.19
36_S84_N0.5000.19
459_K526_K0.5000.19
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2faoA 1 0.4714 100 0.558 Contact Map
2iruA 1 0.4468 100 0.572 Contact Map
1vs0A 1 0.4615 100 0.697 Contact Map
2hivA 1 0.5025 100 0.706 Contact Map
2cfmA 1 0.5139 100 0.709 Contact Map
3gdeA 1 0.4992 100 0.714 Contact Map
1x9nA 1 0.5025 100 0.716 Contact Map
3w1bA 1 0.4975 100 0.737 Contact Map
3l2pA 1 0.4828 100 0.738 Contact Map
1a0iA 1 0.4517 100 0.757 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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