LIGD - BACSU - GREMLIN Contacts

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LIGD - Bifunctional non-homologous end joining protein LigD

UniProt:	O34398	Sequences: MAFTMQPVLTSSPPIGAEWRYEVKYDGYRCILRIHSSGVTLTSRNGVELSSTFPEITQFAKTAFQHLEKELPLTLDGEIVCLVNPCRADFEHLQVRGRLKRPDKIQESANARPCCFLAFDLLERSGEDVTLLSYLDRKKSLRELISAAKLPASPDPYAKETIQSIPCYDHFDQLWEMVIKYDGEGIVAKKTNSKWLEKKRSSDWLKYKNFKQAYVCITGFNPNNGFLTVSVLKNGIMTPIASVSHGMRDEEKSAIREIMEQHGHQTPSGEFTLEPSICAAVQYLTILQGTLREVSFIGFEFQMDWTECTYAQVIRHSKPVHPKLQFTSLDKIIFEKNKKTKEDFIQYMIEVSDYLLPFLKNRAVTVIRYPHGSRSESFFQKNKPDYAPDFVQSFYDGSHEHIVCEDMSTLLWLCNQLALEFHVPFQTIKSRRPAEIVIDLDPPSRDDFLMAVQAANELKRLLDSFGITSYPKLSGNKGIQLYIPLSPEAFTYEETRQFTQLIAEYCTNAFPELFTTERLIKNRHCKLYLDYLQHAEGKTIICPYSTRGNELGTVAAPLYWHEVQSSLTPALFTIDTVIDRIKKQGCPFFDFYRNPQDEPLSAILHQLKKKS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	611 (571)
Sequences:	878 (588)
Seq/√Len:	24.6

BACSU - LIGD

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
259_M	273_L	8.406	1.00
344_F	546_T	6.282	1.00
556_A	577_V	5.665	1.00
21_Y	188_A	5.240	1.00
50_S	57_T	5.021	1.00
562_E	580_R	4.971	1.00
218_T	230_S	4.814	1.00
503_A	529_L	4.765	1.00
369_Y	377_S	4.483	1.00
179_I	209_N	4.320	1.00
443_P	446_D	4.047	1.00
264_H	274_E	3.912	1.00
222_P	271_F	3.872	1.00
188_A	205_L	3.763	1.00
283_Y	286_I	3.622	1.00
284_L	294_V	3.569	1.00
32_L	41_L	3.513	1.00
279_A	299_F	3.487	1.00
491_T	494_E	3.454	1.00
8_V	202_S	3.290	1.00
32_L	60_A	3.150	1.00
431_R	536_E	3.139	1.00
30_C	41_L	3.123	1.00
256_R	260_E	3.045	1.00
138_K	166_P	3.009	1.00
10_T	205_L	2.985	1.00
217_I	279_A	2.892	1.00
81_C	114_C	2.869	1.00
263_G	271_F	2.846	1.00
127_E	140_S	2.845	1.00
500_Q	504_E	2.824	0.99
223_N	226_F	2.807	0.99
471_P	479_I	2.754	0.99
419_L	546_T	2.697	0.99
75_L	118_A	2.683	0.99
284_L	293_E	2.636	0.99
217_I	299_F	2.634	0.99
23_V	183_G	2.476	0.99
519_L	522_N	2.436	0.98
157_Y	166_P	2.376	0.98
212_Q	280_A	2.359	0.98
438_I	502_I	2.348	0.98
20_R	191_T	2.328	0.98
231_V	240_I	2.306	0.98
459_K	463_D	2.234	0.97
226_F	242_S	2.176	0.97
245_H	295_S	2.143	0.96
30_C	79_I	2.140	0.96
553_T	570_A	2.135	0.96
590_D	594_N	2.120	0.96
342_E	346_Q	2.072	0.96
347_Y	577_V	2.048	0.95
546_T	574_I	2.047	0.95
381_K	537_G	2.022	0.95
178_V	183_G	2.021	0.95
558_L	563_V	2.018	0.95
216_C	237_M	2.012	0.95
352_S	356_L	1.978	0.94
348_M	546_T	1.967	0.94
5_M	193_S	1.949	0.94
429_K	487_P	1.933	0.94
214_Y	303_M	1.928	0.94
404_C	409_T	1.923	0.93
473_L	555_A	1.917	0.93
176_E	180_K	1.914	0.93
506_C	529_L	1.910	0.93
291_L	294_V	1.880	0.93
254_A	258_I	1.877	0.93
223_N	252_K	1.874	0.93
188_A	207_Y	1.863	0.92
577_V	581_I	1.845	0.92
220_F	256_R	1.842	0.92
79_I	114_C	1.825	0.91
573_T	576_T	1.806	0.91
556_A	580_R	1.806	0.91
357_P	586_C	1.804	0.91
220_F	271_F	1.804	0.91
438_I	458_L	1.799	0.91
262_H	276_S	1.799	0.91
142_R	165_I	1.796	0.91
455_A	479_I	1.792	0.91
472_K	555_A	1.783	0.91
543_P	555_A	1.776	0.90
214_Y	300_E	1.773	0.90
455_A	560_W	1.724	0.89
75_L	116_F	1.716	0.89
82_L	88_A	1.714	0.89
365_T	379_F	1.699	0.88
132_L	136_D	1.692	0.88
460_R	464_S	1.681	0.88
496_R	532_L	1.661	0.87
518_R	528_Y	1.648	0.87
450_M	453_Q	1.645	0.86
326_F	419_L	1.645	0.86
83_V	87_R	1.627	0.86
541_I	545_S	1.621	0.86
258_I	262_H	1.613	0.85
228_T	270_E	1.606	0.85
329_L	342_E	1.604	0.85
135_L	191_T	1.590	0.85
364_V	413_L	1.581	0.84
218_T	228_T	1.568	0.84
497_Q	500_Q	1.561	0.83
231_V	286_I	1.561	0.83
91_E	223_N	1.555	0.83
515_T	518_R	1.542	0.83
35_H	72_P	1.536	0.82
452_V	566_S	1.532	0.82
34_I	60_A	1.530	0.82
243_V	379_F	1.523	0.82
4_T	198_K	1.514	0.81
468_T	596_Q	1.497	0.81
358_F	435_E	1.496	0.81
355_L	421_F	1.479	0.80
300_E	303_M	1.474	0.80
473_L	479_I	1.473	0.80
335_E	373_S	1.472	0.80
415_N	533_Q	1.471	0.80
216_C	308_C	1.464	0.79
121_L	144_L	1.463	0.79
286_I	479_I	1.460	0.79
436_I	495_T	1.457	0.79
220_F	263_G	1.456	0.79
403_V	428_I	1.448	0.78
469_S	483_I	1.440	0.78
339_K	343_D	1.436	0.78
314_I	317_S	1.429	0.77
132_L	140_S	1.409	0.76
454_A	514_F	1.405	0.76
138_K	171_F	1.399	0.76
474_S	540_I	1.399	0.76
392_Q	405_E	1.352	0.73
541_I	555_A	1.351	0.73
127_E	132_L	1.346	0.73
422_H	541_I	1.343	0.73
405_E	409_T	1.342	0.73
258_I	301_F	1.340	0.73
191_T	526_K	1.338	0.73
218_T	242_S	1.335	0.72
456_N	564_Q	1.331	0.72
351_V	581_I	1.327	0.72
228_T	239_P	1.326	0.72
334_F	552_G	1.325	0.72
248_R	251_E	1.323	0.72
559_Y	584_Q	1.323	0.72
219_G	244_S	1.311	0.71
332_I	340_T	1.305	0.71
59_F	353_D	1.301	0.70
398_S	526_K	1.299	0.70
193_S	203_D	1.294	0.70
437_V	536_E	1.290	0.70
30_C	53_F	1.287	0.70
365_T	424_P	1.286	0.70
18_E	192_N	1.278	0.69
472_K	543_P	1.277	0.69
15_I	172_D	1.270	0.69
33_R	74_T	1.266	0.68
326_F	333_I	1.263	0.68
118_A	121_L	1.262	0.68
457_E	510_F	1.261	0.68
285_T	294_V	1.253	0.67
214_Y	302_Q	1.251	0.67
58_Q	61_K	1.249	0.67
558_L	569_P	1.249	0.67
326_F	329_L	1.249	0.67
34_I	238_T	1.240	0.67
176_E	526_K	1.238	0.67
30_C	116_F	1.231	0.66
457_E	514_F	1.230	0.66
459_K	560_W	1.221	0.65
356_L	406_D	1.220	0.65
425_F	540_I	1.213	0.65
471_P	563_V	1.213	0.65
213_A	311_A	1.211	0.65
311_A	485_L	1.209	0.65
392_Q	406_D	1.205	0.64
368_R	380_Q	1.204	0.64
339_K	574_I	1.200	0.64
334_F	344_F	1.197	0.64
449_L	452_V	1.196	0.64
32_L	116_F	1.188	0.63
52_T	280_A	1.187	0.63
196_L	199_K	1.183	0.63
262_H	277_I	1.180	0.63
77_G	116_F	1.177	0.62
348_M	414_C	1.174	0.62
457_E	461_L	1.174	0.62
53_F	79_I	1.174	0.62
213_A	283_Y	1.162	0.61
373_S	377_S	1.161	0.61
518_R	535_A	1.156	0.61
277_I	299_F	1.153	0.61
186_I	283_Y	1.151	0.61
164_S	167_C	1.148	0.61
427_T	434_A	1.146	0.60
473_L	556_A	1.145	0.60
446_D	515_T	1.141	0.60
266_T	274_E	1.140	0.60
260_E	263_G	1.139	0.60
355_L	414_C	1.139	0.60
540_I	555_A	1.138	0.60
470_Y	594_N	1.129	0.59
126_G	351_V	1.124	0.59
365_T	401_H	1.124	0.59
278_C	308_C	1.117	0.58
115_C	156_P	1.115	0.58
135_L	192_N	1.108	0.58
461_L	509_A	1.104	0.57
558_L	566_S	1.098	0.57
229_V	247_M	1.098	0.57
172_D	176_E	1.092	0.57
355_L	584_Q	1.090	0.56
463_D	468_T	1.088	0.56
253_S	257_E	1.086	0.56
142_R	146_S	1.085	0.56
190_K	203_D	1.075	0.55
476_N	549_N	1.074	0.55
307_E	512_E	1.073	0.55
423_V	542_C	1.071	0.55
367_I	548_G	1.070	0.55
250_E	573_T	1.067	0.55
33_R	42_T	1.063	0.55
13_P	293_E	1.062	0.54
242_S	295_S	1.061	0.54
588_F	591_F	1.059	0.54
216_C	230_S	1.057	0.54
515_T	522_N	1.056	0.54
461_L	506_C	1.053	0.54
402_I	413_L	1.053	0.54
71_L	125_S	1.049	0.54
251_E	254_A	1.049	0.54
273_L	421_F	1.047	0.53
74_T	460_R	1.043	0.53
251_E	296_F	1.042	0.53
310_Y	314_I	1.040	0.53
474_S	555_A	1.039	0.53
20_R	186_I	1.037	0.53
334_F	337_N	1.034	0.52
382_N	399_H	1.031	0.52
350_E	578_I	1.030	0.52
213_A	231_V	1.029	0.52
556_A	562_E	1.022	0.52
215_V	229_V	1.022	0.52
333_I	474_S	1.016	0.51
167_C	334_F	1.016	0.51
91_E	95_V	1.016	0.51
60_A	118_A	1.015	0.51
136_D	139_K	1.011	0.51
533_Q	540_I	1.009	0.51
139_K	143_E	1.006	0.50
82_L	117_L	1.005	0.50
326_F	331_K	1.002	0.50
116_F	221_N	1.000	0.50
327_T	541_I	0.994	0.50
474_S	522_N	0.994	0.50
458_L	506_C	0.992	0.49
6_Q	44_R	0.991	0.49
352_S	407_M	0.989	0.49
382_N	533_Q	0.987	0.49
231_V	311_A	0.985	0.49
170_H	173_Q	0.977	0.48
5_M	327_T	0.976	0.48
221_N	228_T	0.975	0.48
311_A	315_R	0.973	0.48
15_I	186_I	0.967	0.48
474_S	483_I	0.967	0.48
124_R	129_V	0.965	0.48
40_T	529_L	0.964	0.47
305_W	437_V	0.957	0.47
210_F	293_E	0.956	0.47
13_P	383_K	0.953	0.47
331_K	566_S	0.951	0.47
192_N	250_E	0.945	0.46
203_D	273_L	0.942	0.46
70_E	73_L	0.942	0.46
21_Y	207_Y	0.942	0.46
369_Y	425_F	0.941	0.46
49_L	533_Q	0.941	0.46
214_Y	219_G	0.940	0.46
271_F	279_A	0.932	0.45
355_L	410_L	0.931	0.45
98_R	543_P	0.930	0.45
469_S	596_Q	0.930	0.45
335_E	374_R	0.930	0.45
133_S	352_S	0.928	0.45
242_S	290_T	0.927	0.45
344_F	419_L	0.925	0.45
87_R	182_D	0.924	0.45
381_K	474_S	0.923	0.45
25_Y	43_S	0.921	0.44
426_Q	492_Y	0.919	0.44
9_L	285_T	0.916	0.44
546_T	554_V	0.915	0.44
533_Q	588_F	0.915	0.44
285_T	293_E	0.915	0.44
434_A	487_P	0.912	0.44
216_C	305_W	0.909	0.44
351_V	376_E	0.907	0.43
73_L	165_I	0.906	0.43
361_N	428_I	0.904	0.43
135_L	138_K	0.902	0.43
333_I	344_F	0.901	0.43
32_L	220_F	0.900	0.43
369_Y	540_I	0.897	0.43
38_G	236_I	0.895	0.43
138_K	157_Y	0.891	0.42
187_V	541_I	0.890	0.42
382_N	415_N	0.888	0.42
413_L	421_F	0.888	0.42
528_Y	533_Q	0.888	0.42
214_Y	244_S	0.887	0.42
415_N	492_Y	0.884	0.42
333_I	556_A	0.878	0.41
229_V	291_L	0.878	0.41
424_P	480_Q	0.878	0.41
126_G	485_L	0.877	0.41
486_S	596_Q	0.875	0.41
14_P	514_F	0.873	0.41
228_T	242_S	0.872	0.41
88_A	183_G	0.869	0.41
60_A	474_S	0.868	0.41
493_E	535_A	0.867	0.41
578_I	582_K	0.867	0.41
324_L	411_L	0.865	0.40
418_A	422_H	0.863	0.40
282_Q	297_I	0.857	0.40
148_A	151_P	0.857	0.40
467_I	476_N	0.856	0.40
265_Q	340_T	0.855	0.40
216_C	433_P	0.854	0.40
218_T	232_L	0.854	0.40
43_S	383_K	0.852	0.40
89_D	92_H	0.852	0.40
591_F	594_N	0.852	0.40
187_V	447_D	0.852	0.40
255_I	259_M	0.850	0.39
395_Y	431_R	0.845	0.39
40_T	48_E	0.845	0.39
318_K	321_H	0.840	0.39
420_E	437_V	0.838	0.39
242_S	269_G	0.838	0.39
73_L	124_R	0.837	0.39
118_A	328_S	0.835	0.38
81_C	92_H	0.833	0.38
554_V	572_F	0.832	0.38
133_S	203_D	0.832	0.38
18_E	186_I	0.831	0.38
30_C	588_F	0.831	0.38
61_K	431_R	0.829	0.38
492_Y	538_K	0.829	0.38
311_A	314_I	0.826	0.38
391_V	411_L	0.826	0.38
233_K	238_T	0.824	0.38
460_R	463_D	0.824	0.38
201_S	359_L	0.824	0.38
271_F	391_V	0.822	0.37
242_S	425_F	0.822	0.37
568_T	571_L	0.820	0.37
57_T	429_K	0.819	0.37
136_D	429_K	0.819	0.37
242_S	293_E	0.818	0.37
66_H	276_S	0.816	0.37
396_D	401_H	0.816	0.37
380_Q	532_L	0.814	0.37
459_K	469_S	0.814	0.37
515_T	520_I	0.813	0.37
10_T	213_A	0.812	0.37
347_Y	482_Y	0.812	0.37
361_N	405_E	0.810	0.37
30_C	57_T	0.809	0.37
347_Y	351_V	0.809	0.37
116_F	146_S	0.809	0.37
561_H	564_Q	0.808	0.37
358_F	544_Y	0.807	0.36
34_I	451_A	0.807	0.36
255_I	299_F	0.806	0.36
238_T	550_E	0.805	0.36
243_V	281_V	0.803	0.36
279_A	296_F	0.802	0.36
375_S	550_E	0.799	0.36
455_A	459_K	0.798	0.36
436_I	531_Y	0.798	0.36
328_S	331_K	0.798	0.36
404_C	410_L	0.795	0.36
87_R	334_F	0.793	0.36
244_S	247_M	0.793	0.36
463_D	469_S	0.792	0.35
117_L	351_V	0.789	0.35
391_V	409_T	0.789	0.35
20_R	138_K	0.787	0.35
359_L	461_L	0.786	0.35
452_V	567_L	0.786	0.35
7_P	338_K	0.784	0.35
191_T	554_V	0.783	0.35
343_D	346_Q	0.783	0.35
193_S	196_L	0.782	0.35
223_N	271_F	0.781	0.35
422_H	477_K	0.780	0.35
592_Y	596_Q	0.779	0.35
485_L	499_T	0.777	0.35
229_V	286_I	0.774	0.34
533_Q	538_K	0.773	0.34
425_F	520_I	0.773	0.34
110_N	113_P	0.770	0.34
468_T	526_K	0.770	0.34
330_D	449_L	0.769	0.34
516_T	529_L	0.767	0.34
471_P	588_F	0.766	0.34
312_Q	317_S	0.766	0.34
196_L	201_S	0.766	0.34
415_N	538_K	0.761	0.33
178_V	221_N	0.761	0.33
325_Q	328_S	0.759	0.33
229_V	243_V	0.758	0.33
121_L	140_S	0.756	0.33
13_P	207_Y	0.755	0.33
312_Q	318_K	0.755	0.33
358_F	543_P	0.754	0.33
364_V	574_I	0.754	0.33
139_K	497_Q	0.753	0.33
345_I	415_N	0.751	0.33
476_N	533_Q	0.750	0.33
49_L	476_N	0.749	0.33
133_S	136_D	0.749	0.33
230_S	287_L	0.745	0.32
225_G	259_M	0.744	0.32
590_D	593_R	0.744	0.32
531_Y	578_I	0.744	0.32
30_C	598_E	0.743	0.32
337_N	552_G	0.743	0.32
14_P	476_N	0.743	0.32
3_F	537_G	0.742	0.32
298_G	344_F	0.742	0.32
316_H	437_V	0.741	0.32
225_G	479_I	0.738	0.32
273_L	286_I	0.737	0.32
310_Y	313_V	0.737	0.32
247_M	252_K	0.735	0.32
317_S	321_H	0.734	0.32
519_L	572_F	0.732	0.32
279_A	347_Y	0.732	0.32
458_L	481_L	0.732	0.32
325_Q	577_V	0.731	0.32
217_I	263_G	0.731	0.32
212_Q	305_W	0.731	0.32
448_F	452_V	0.730	0.32
365_T	502_I	0.729	0.31
477_K	520_I	0.728	0.31
34_I	70_E	0.728	0.31
333_I	522_N	0.728	0.31
367_I	477_K	0.727	0.31
401_H	535_A	0.727	0.31
315_R	319_P	0.727	0.31
49_L	415_N	0.726	0.31
5_M	533_Q	0.722	0.31
112_R	294_V	0.722	0.31
25_Y	293_E	0.721	0.31
399_H	418_A	0.721	0.31
367_I	422_H	0.721	0.31
285_T	436_I	0.719	0.31
215_V	331_K	0.718	0.31
476_N	514_F	0.718	0.31
250_E	274_E	0.716	0.31
382_N	476_N	0.715	0.31
544_Y	586_C	0.714	0.31
166_P	171_F	0.714	0.31
289_G	293_E	0.714	0.31
178_V	473_L	0.712	0.30
368_R	420_E	0.711	0.30
173_Q	177_M	0.711	0.30
255_I	271_F	0.710	0.30
116_F	406_D	0.710	0.30
403_V	409_T	0.709	0.30
327_T	393_S	0.708	0.30
552_G	572_F	0.708	0.30
40_T	288_Q	0.706	0.30
24_K	27_G	0.706	0.30
444_S	528_Y	0.705	0.30
344_F	414_C	0.705	0.30
443_P	515_T	0.704	0.30
217_I	259_M	0.704	0.30
410_L	421_F	0.703	0.30
18_E	203_D	0.702	0.30
391_V	402_I	0.702	0.30
23_V	165_I	0.701	0.30
563_V	567_L	0.701	0.30
524_H	552_G	0.700	0.30
4_T	8_V	0.700	0.30
3_F	199_K	0.700	0.30
147_A	360_K	0.699	0.30
283_Y	433_P	0.698	0.30
214_Y	308_C	0.698	0.30
187_V	574_I	0.698	0.30
305_W	308_C	0.698	0.30
213_A	286_I	0.697	0.30
3_F	198_K	0.696	0.29
30_C	465_F	0.695	0.29
367_I	514_F	0.694	0.29
257_E	260_E	0.692	0.29
225_G	256_R	0.691	0.29
164_S	281_V	0.690	0.29
349_I	407_M	0.688	0.29
326_F	411_L	0.688	0.29
482_Y	533_Q	0.688	0.29
224_N	259_M	0.686	0.29
232_L	236_I	0.684	0.29
363_A	532_L	0.684	0.29
270_E	294_V	0.683	0.29
558_L	565_S	0.682	0.29
49_L	422_H	0.681	0.29
175_W	207_Y	0.681	0.29
26_D	29_R	0.681	0.29
24_K	29_R	0.681	0.29
382_N	514_F	0.681	0.29
71_L	75_L	0.681	0.29
335_E	355_L	0.676	0.28
213_A	308_C	0.676	0.28
22_E	26_D	0.675	0.28
125_S	367_I	0.674	0.28
41_L	361_N	0.674	0.28
520_I	524_H	0.674	0.28
417_L	544_Y	0.673	0.28
14_P	19_W	0.673	0.28
138_K	377_S	0.673	0.28
18_E	143_E	0.673	0.28
9_L	213_A	0.672	0.28
324_L	578_I	0.672	0.28
15_I	432_R	0.671	0.28
114_C	228_T	0.670	0.28
425_F	471_P	0.670	0.28
216_C	231_V	0.669	0.28
225_G	413_L	0.668	0.28
96_R	114_C	0.668	0.28
217_I	273_L	0.667	0.28
18_E	190_K	0.667	0.28
245_H	279_A	0.667	0.28
273_L	536_E	0.665	0.28
373_S	419_L	0.665	0.28
176_E	234_N	0.664	0.28
93_L	241_A	0.663	0.28
149_K	437_V	0.662	0.27
55_E	71_L	0.662	0.27
587_P	591_F	0.661	0.27
143_E	250_E	0.661	0.27
40_T	255_I	0.660	0.27
54_P	58_Q	0.659	0.27
12_S	469_S	0.657	0.27
173_Q	201_S	0.656	0.27
130_T	198_K	0.653	0.27
87_R	170_H	0.652	0.27
260_E	563_V	0.652	0.27
402_I	455_A	0.652	0.27
310_Y	315_R	0.651	0.27
309_T	361_N	0.650	0.27
118_A	145_I	0.650	0.27
382_N	548_G	0.650	0.27
35_H	38_G	0.649	0.27
496_R	500_Q	0.649	0.27
234_N	570_A	0.649	0.27
217_I	512_E	0.648	0.27
136_D	144_L	0.646	0.27
483_I	528_Y	0.645	0.26
398_S	401_H	0.645	0.26
425_F	435_E	0.644	0.26
423_V	541_I	0.643	0.26
493_E	497_Q	0.643	0.26
332_I	338_K	0.643	0.26
518_R	533_Q	0.642	0.26
209_N	531_Y	0.642	0.26
13_P	285_T	0.641	0.26
563_V	566_S	0.641	0.26
459_K	474_S	0.641	0.26
253_S	487_P	0.640	0.26
146_S	151_P	0.639	0.26
61_K	263_G	0.639	0.26
49_L	540_I	0.637	0.26
373_S	474_S	0.635	0.26
39_V	279_A	0.635	0.26
49_L	492_Y	0.634	0.26
387_A	391_V	0.633	0.26
242_S	586_C	0.632	0.26
53_F	97_G	0.631	0.26
18_E	273_L	0.631	0.26
138_K	175_W	0.631	0.26
519_L	552_G	0.630	0.26
72_P	555_A	0.629	0.26
403_V	554_V	0.629	0.26
361_N	573_T	0.627	0.25
6_Q	200_R	0.626	0.25
140_S	143_E	0.625	0.25
170_H	187_V	0.625	0.25
210_F	284_L	0.625	0.25
411_L	508_N	0.623	0.25
35_H	40_T	0.623	0.25
193_S	543_P	0.623	0.25
269_G	345_I	0.621	0.25
170_H	389_D	0.621	0.25
20_R	139_K	0.621	0.25
97_G	352_S	0.621	0.25
14_P	587_P	0.620	0.25
259_M	284_L	0.618	0.25
331_K	371_H	0.617	0.25
418_A	506_C	0.617	0.25
73_L	186_I	0.617	0.25
502_I	559_Y	0.617	0.25
415_N	588_F	0.616	0.25
261_Q	332_I	0.615	0.25
214_Y	280_A	0.614	0.25
347_Y	452_V	0.614	0.25
56_I	469_S	0.614	0.25
247_M	279_A	0.613	0.25
236_I	573_T	0.612	0.25
354_Y	585_G	0.611	0.25
520_I	543_P	0.611	0.25
193_S	308_C	0.611	0.25
223_N	268_S	0.608	0.24
118_A	412_W	0.607	0.24
352_S	466_G	0.607	0.24
176_E	544_Y	0.606	0.24
113_P	427_T	0.606	0.24
558_L	576_T	0.605	0.24
229_V	537_G	0.604	0.24
342_E	408_S	0.604	0.24
317_S	323_K	0.604	0.24
452_V	563_V	0.603	0.24
329_L	476_N	0.603	0.24
60_A	343_D	0.602	0.24
494_E	598_E	0.601	0.24
499_T	544_Y	0.601	0.24
125_S	267_P	0.601	0.24
226_F	487_P	0.601	0.24
36_S	350_E	0.601	0.24
110_N	132_L	0.600	0.24
203_D	364_V	0.600	0.24
231_V	283_Y	0.599	0.24
471_P	587_P	0.599	0.24
345_I	414_C	0.598	0.24
449_L	566_S	0.596	0.24
293_E	297_I	0.596	0.24
232_L	250_E	0.595	0.24
397_G	401_H	0.595	0.24
414_C	546_T	0.594	0.24
569_P	576_T	0.593	0.24
239_P	242_S	0.593	0.24
471_P	531_Y	0.593	0.24
368_R	378_F	0.593	0.24
518_R	540_I	0.593	0.24
142_R	157_Y	0.592	0.24
40_T	180_K	0.592	0.24
66_H	374_R	0.592	0.24
156_P	400_E	0.591	0.24
22_E	27_G	0.591	0.24
58_Q	361_N	0.591	0.24
214_Y	278_C	0.590	0.24
245_H	288_Q	0.589	0.23
30_C	471_P	0.589	0.23
35_H	306_T	0.588	0.23
238_T	436_I	0.588	0.23
415_N	518_R	0.588	0.23
421_F	514_F	0.587	0.23
313_V	321_H	0.587	0.23
492_Y	533_Q	0.587	0.23
345_I	492_Y	0.586	0.23
240_I	286_I	0.585	0.23
371_H	404_C	0.585	0.23
334_F	567_L	0.584	0.23
144_L	147_A	0.583	0.23
388_P	412_W	0.583	0.23
553_T	573_T	0.583	0.23
336_K	374_R	0.583	0.23
444_S	447_D	0.582	0.23
143_E	274_E	0.582	0.23
297_I	379_F	0.582	0.23
145_I	437_V	0.581	0.23
156_P	183_G	0.581	0.23
517_E	522_N	0.581	0.23
61_K	502_I	0.581	0.23
237_M	277_I	0.580	0.23
213_A	296_F	0.580	0.23
481_L	515_T	0.580	0.23
59_F	553_T	0.580	0.23
393_S	405_E	0.579	0.23
404_C	567_L	0.577	0.23
188_A	388_P	0.576	0.23
343_D	575_D	0.576	0.23
331_K	448_F	0.576	0.23
130_T	199_K	0.575	0.23
9_L	414_C	0.575	0.23
116_F	500_Q	0.574	0.23
329_L	422_H	0.573	0.23
22_E	29_R	0.573	0.23
30_C	367_I	0.572	0.23
448_F	451_A	0.572	0.23
171_F	346_Q	0.572	0.23
413_L	418_A	0.568	0.22
73_L	151_P	0.568	0.22
72_P	187_V	0.568	0.22
359_L	453_Q	0.567	0.22
267_P	272_T	0.567	0.22
418_A	474_S	0.566	0.22
72_P	125_S	0.566	0.22
58_Q	149_K	0.566	0.22
417_L	518_R	0.565	0.22
51_S	502_I	0.564	0.22
171_F	175_W	0.564	0.22
510_F	543_P	0.564	0.22
126_G	484_P	0.563	0.22
544_Y	556_A	0.563	0.22
412_W	416_Q	0.563	0.22
510_F	555_A	0.562	0.22
329_L	438_I	0.562	0.22
306_T	524_H	0.562	0.22
228_T	303_M	0.561	0.22
30_C	505_Y	0.560	0.22
9_L	212_Q	0.560	0.22
39_V	86_C	0.559	0.22
260_E	309_T	0.559	0.22
412_W	533_Q	0.558	0.22
419_L	562_E	0.556	0.22
542_C	567_L	0.556	0.22
60_A	473_L	0.556	0.22
333_I	572_F	0.556	0.22
118_A	122_L	0.554	0.22
522_N	552_G	0.554	0.22
379_F	589_F	0.554	0.22
66_H	307_E	0.554	0.22
425_F	533_Q	0.553	0.22
580_R	587_P	0.552	0.22
54_P	57_T	0.552	0.22
399_H	563_V	0.551	0.22
131_L	309_T	0.551	0.22
321_H	330_D	0.551	0.22
198_K	504_E	0.551	0.22
70_E	448_F	0.550	0.22
59_F	151_P	0.549	0.21
231_V	472_K	0.549	0.21
343_D	546_T	0.549	0.21
350_E	561_H	0.548	0.21
145_I	402_I	0.548	0.21
244_S	303_M	0.548	0.21
461_L	505_Y	0.547	0.21
382_N	454_A	0.547	0.21
122_L	132_L	0.547	0.21
285_T	288_Q	0.547	0.21
30_C	54_P	0.546	0.21
334_F	553_T	0.546	0.21
34_I	39_V	0.545	0.21
45_N	493_E	0.545	0.21
426_Q	521_K	0.545	0.21
198_K	408_S	0.544	0.21
415_N	482_Y	0.542	0.21
97_G	409_T	0.542	0.21
573_T	581_I	0.542	0.21
187_V	294_V	0.542	0.21
9_L	529_L	0.541	0.21
211_K	265_Q	0.541	0.21
429_K	488_E	0.541	0.21
390_F	533_Q	0.540	0.21
435_E	507_T	0.540	0.21
245_H	424_P	0.540	0.21
435_E	514_F	0.539	0.21
326_F	345_I	0.539	0.21
39_V	554_V	0.539	0.21
79_I	412_W	0.539	0.21
138_K	569_P	0.537	0.21
425_F	531_Y	0.537	0.21
435_E	533_Q	0.536	0.21
333_I	438_I	0.536	0.21
436_I	499_T	0.536	0.21
358_F	472_K	0.536	0.21
302_Q	551_L	0.536	0.21
138_K	205_L	0.535	0.21
474_S	585_G	0.534	0.21
110_N	281_V	0.534	0.21
209_N	212_Q	0.533	0.21
437_V	593_R	0.533	0.21
60_A	222_P	0.533	0.21
80_V	281_V	0.532	0.21
126_G	327_T	0.532	0.21
132_L	419_L	0.531	0.21
254_A	361_N	0.531	0.21
56_I	59_F	0.531	0.21
422_H	467_I	0.531	0.21
471_P	566_S	0.530	0.21
174_L	192_N	0.530	0.21
74_T	122_L	0.530	0.21
75_L	352_S	0.530	0.21
41_L	543_P	0.529	0.21
92_H	95_V	0.529	0.21
131_L	196_L	0.528	0.20
88_A	222_P	0.528	0.20
122_L	450_M	0.528	0.20
488_E	597_D	0.528	0.20
346_Q	349_I	0.528	0.20
429_K	469_S	0.527	0.20
295_S	505_Y	0.527	0.20
20_R	135_L	0.526	0.20
473_L	576_T	0.525	0.20
96_R	367_I	0.525	0.20
20_R	134_Y	0.525	0.20
287_L	298_G	0.525	0.20
291_L	334_F	0.525	0.20
334_F	452_V	0.525	0.20
280_A	300_E	0.525	0.20
473_L	566_S	0.525	0.20
233_K	262_H	0.524	0.20
392_Q	565_S	0.523	0.20
165_I	424_P	0.523	0.20
180_K	264_H	0.523	0.20
329_L	587_P	0.523	0.20
374_R	574_I	0.523	0.20
518_R	521_K	0.523	0.20
352_S	506_C	0.522	0.20
385_D	535_A	0.522	0.20
453_Q	513_L	0.522	0.20
138_K	540_I	0.522	0.20
427_T	493_E	0.521	0.20
462_L	481_L	0.521	0.20
313_V	316_H	0.520	0.20
397_G	561_H	0.519	0.20
422_H	506_C	0.519	0.20
13_P	481_L	0.518	0.20
85_P	121_L	0.518	0.20
218_T	526_K	0.518	0.20
494_E	554_V	0.518	0.20
357_P	544_Y	0.517	0.20
355_L	577_V	0.516	0.20
59_F	220_F	0.515	0.20
73_L	121_L	0.515	0.20
544_Y	585_G	0.513	0.20
178_V	581_I	0.512	0.20
191_T	402_I	0.512	0.20
331_K	365_T	0.512	0.20
554_V	577_V	0.512	0.20
286_I	472_K	0.511	0.20
488_E	558_L	0.509	0.20
223_N	556_A	0.506	0.19
142_R	150_L	0.506	0.19
281_V	504_E	0.506	0.19
226_F	252_K	0.505	0.19
239_P	290_T	0.505	0.19
272_T	363_A	0.505	0.19
429_K	508_N	0.504	0.19
495_T	503_A	0.504	0.19
223_N	247_M	0.504	0.19
345_I	466_G	0.504	0.19
323_K	353_D	0.503	0.19
276_S	515_T	0.503	0.19
45_N	229_V	0.503	0.19
84_N	321_H	0.502	0.19
218_T	229_V	0.502	0.19
212_Q	298_G	0.501	0.19
194_K	253_S	0.500	0.19
124_R	448_F	0.500	0.19
36_S	84_N	0.500	0.19
459_K	526_K	0.500	0.19

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2faoA	1	0.4714	100	0.558	Contact Map
2iruA	1	0.4468	100	0.572	Contact Map
1vs0A	1	0.4615	100	0.697	Contact Map
2hivA	1	0.5025	100	0.706	Contact Map
2cfmA	1	0.5139	100	0.709	Contact Map
3gdeA	1	0.4992	100	0.714	Contact Map
1x9nA	1	0.5025	100	0.716	Contact Map
3w1bA	1	0.4975	100	0.737	Contact Map
3l2pA	1	0.4828	100	0.738	Contact Map
1a0iA	1	0.4517	100	0.757	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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