GREMLIN Database
YJJA - Uncharacterized protein YjjA
UniProt: O34394 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 270 (240)
Sequences: 4199 (3170)
Seq/√Len: 204.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
25_I30_G4.4221.00
230_A236_A4.0601.00
60_A164_L3.7491.00
146_G170_Q3.4201.00
199_A238_A3.1521.00
236_A249_A2.7651.00
139_T162_S2.5251.00
62_W97_A2.4931.00
9_R31_I2.4731.00
60_A141_M2.4201.00
155_F158_E2.3691.00
193_A229_A2.3241.00
144_L165_P2.3121.00
98_C104_L2.2481.00
203_R238_A2.2221.00
41_V172_I2.2081.00
75_V110_L2.1751.00
24_I28_Q2.1701.00
41_V170_Q2.1431.00
49_E77_M2.1391.00
61_D138_K2.0771.00
22_S34_I2.0311.00
127_I155_F2.0221.00
202_V239_L1.9991.00
174_P204_S1.9351.00
230_A249_A1.9051.00
116_A129_S1.8941.00
228_A244_I1.8921.00
24_I256_G1.8821.00
39_G174_P1.8581.00
96_A112_I1.8541.00
230_A239_L1.8481.00
65_F71_L1.8151.00
72_E106_A1.8081.00
144_L148_K1.7641.00
12_I18_T1.7451.00
131_E159_K1.7441.00
123_T152_L1.7361.00
193_A262_L1.7331.00
12_I22_S1.7261.00
17_K69_I1.7061.00
11_A191_V1.6691.00
237_E241_E1.6521.00
62_W95_K1.6491.00
237_E240_R1.6471.00
62_W140_V1.6361.00
236_A240_R1.6181.00
106_A109_K1.6101.00
206_F242_E1.6061.00
22_S32_P1.5611.00
153_M157_E1.5601.00
40_T69_I1.5591.00
40_T171_H1.5591.00
28_Q263_A1.5431.00
150_P154_A1.5421.00
203_R242_E1.5291.00
122_T125_G1.5291.00
135_F138_K1.5051.00
97_A126_L1.5031.00
124_R149_A1.4981.00
65_F74_L1.4931.00
135_F161_A1.4721.00
239_L246_R1.4641.00
248_L261_E1.4371.00
229_A248_L1.4291.00
196_F205_L1.4151.00
229_A258_M1.4081.00
253_E257_A1.4041.00
120_D125_G1.4031.00
139_T164_L1.4001.00
73_T168_P1.3971.00
228_A239_L1.3841.00
42_Y73_T1.3721.00
154_A157_E1.3651.00
250_P257_A1.3501.00
197_T201_Q1.3361.00
196_F202_V1.3351.00
68_G102_K1.3241.00
25_I32_P1.3131.00
195_C258_M1.3021.00
119_E129_S1.3011.00
39_G172_I1.2961.00
153_M165_P1.2921.00
146_G167_L1.2761.00
238_A241_E1.2701.00
239_L244_I1.2621.00
95_K115_E1.2491.00
26_E32_P1.2401.00
227_I248_L1.2401.00
9_R33_V1.2371.00
54_T59_K1.2331.00
231_V235_T1.2171.00
22_S26_E1.2111.00
238_A242_E1.2091.00
61_D139_T1.2061.00
59_K139_T1.2001.00
252_I257_A1.1951.00
232_G235_T1.1791.00
98_C107_L1.1791.00
23_T27_K1.1781.00
173_P207_D1.1721.00
98_C117_S1.1711.00
50_P54_T1.1481.00
233_K253_E1.1461.00
199_A234_V1.1441.00
23_T26_E1.1401.00
171_H200_I1.1401.00
193_A227_I1.1351.00
134_D138_K1.1301.00
196_F228_A1.1241.00
104_L108_K1.1161.00
180_E184_R1.1051.00
142_V153_M1.0901.00
123_T127_I1.0841.00
116_A126_L1.0721.00
64_I130_L1.0391.00
254_R257_A1.0391.00
206_F244_I1.0271.00
186_L221_V1.0241.00
71_L106_A1.0171.00
37_L204_S1.0151.00
151_A155_F1.0051.00
104_L117_S1.0021.00
184_R188_N0.9951.00
14_G201_Q0.9861.00
173_P204_S0.9851.00
33_V191_V0.9811.00
63_V96_A0.9761.00
21_I195_C0.9671.00
8_K192_D0.9651.00
12_I195_C0.9570.99
148_K165_P0.9380.99
147_E200_I0.9340.99
124_R151_A0.9300.99
68_G106_A0.9220.99
19_E34_I0.9190.99
63_V143_Q0.9070.99
155_F159_K0.8860.99
140_V161_A0.8840.99
24_I27_K0.8820.99
185_E190_E0.8810.99
108_K113_T0.8790.99
70_G143_Q0.8710.99
195_C229_A0.8680.99
46_K49_E0.8650.99
199_A235_T0.8640.99
76_D110_L0.8590.99
49_E81_I0.8580.99
54_T164_L0.8570.99
43_L170_Q0.8560.99
38_Q204_S0.8520.99
181_R185_E0.8510.99
62_W116_A0.8510.99
49_E53_R0.8390.99
137_G161_A0.8380.99
72_E76_D0.8340.99
99_R123_T0.8290.98
33_V185_E0.8250.98
210_K213_G0.8240.98
63_V94_A0.8210.98
38_Q171_H0.8200.98
39_G175_E0.8180.98
123_T151_A0.8170.98
195_C262_L0.8160.98
71_L103_T0.8110.98
147_E171_H0.8090.98
70_G142_V0.8070.98
204_S208_F0.8040.98
16_R19_E0.8000.98
43_L167_L0.7990.98
40_T73_T0.7950.98
47_Q50_P0.7950.98
233_K237_E0.7920.98
54_T58_E0.7910.98
37_L205_L0.7900.98
12_I32_P0.7850.98
10_V193_A0.7840.98
239_L243_G0.7820.98
105_S109_K0.7810.98
19_E23_T0.7810.98
12_I25_I0.7800.98
101_Y121_G0.7740.98
12_I34_I0.7720.98
122_T233_K0.7710.98
111_G114_P0.7700.98
194_V228_A0.7700.98
250_P261_E0.7660.97
50_P53_R0.7660.97
141_M166_I0.7640.97
48_V168_P0.7620.97
108_K114_P0.7600.97
37_L208_F0.7570.97
107_L112_I0.7570.97
260_V264_K0.7550.97
123_T171_H0.7540.97
240_R245_T0.7530.97
69_I73_T0.7520.97
143_Q168_P0.7510.97
98_C114_P0.7510.97
176_E208_F0.7470.97
229_A261_E0.7460.97
74_L143_Q0.7410.97
149_A234_V0.7340.97
18_T34_I0.7320.97
102_K105_S0.7290.97
21_I25_I0.7250.96
183_C187_M0.7200.96
79_E82_G0.7180.96
72_E109_K0.7160.96
127_I159_K0.7160.96
95_K133_H0.7160.96
38_Q198_T0.7150.96
64_I126_L0.7150.96
73_T76_D0.7110.96
154_A158_E0.7100.96
142_V152_L0.7100.96
142_V163_V0.7080.96
99_R126_L0.7050.96
150_P165_P0.7050.96
14_G103_T0.6980.96
157_E163_V0.6950.96
251_E260_V0.6940.96
227_I247_L0.6860.95
118_D121_G0.6840.95
156_L161_A0.6840.95
24_I259_I0.6820.95
106_A110_L0.6800.95
42_Y76_D0.6790.95
144_L150_P0.6750.95
65_F96_A0.6710.95
43_L46_K0.6680.94
21_I197_T0.6640.94
121_G125_G0.6640.94
62_W130_L0.6630.94
53_R83_L0.6630.94
35_R176_E0.6620.94
16_R34_I0.6610.94
121_G254_R0.6530.94
147_E167_L0.6520.94
144_L153_M0.6490.94
131_E155_F0.6480.94
51_D164_L0.6480.94
125_G129_S0.6460.93
65_F143_Q0.6450.93
104_L114_P0.6450.93
182_L185_E0.6400.93
151_A154_A0.6370.93
145_H167_L0.6340.93
144_L167_L0.6330.93
97_A129_S0.6320.93
63_V141_M0.6320.93
26_E34_I0.6310.93
74_L168_P0.6310.93
97_A197_T0.6270.92
105_S108_K0.6250.92
193_A248_L0.6250.92
62_W129_S0.6230.92
126_L130_L0.6210.92
64_I152_L0.6210.92
123_T148_K0.6210.92
234_V253_E0.6190.92
143_Q166_I0.6180.92
119_E125_G0.6150.92
259_I262_L0.6120.92
260_V263_A0.6110.91
197_T255_M0.6110.91
148_K171_H0.6080.91
200_I232_G0.6060.91
48_V77_M0.6050.91
257_A261_E0.6050.91
17_K68_G0.6020.91
189_D225_R0.6020.91
61_D93_Q0.5990.91
96_A107_L0.5980.91
62_W138_K0.5980.91
233_K249_A0.5970.90
77_M80_K0.5960.90
38_Q200_I0.5930.90
64_I97_A0.5930.90
127_I130_L0.5920.90
142_V148_K0.5900.90
250_P253_E0.5890.90
49_E80_K0.5860.90
229_A247_L0.5860.90
97_A118_D0.5850.90
181_R184_R0.5840.90
9_R192_D0.5840.90
122_T234_V0.5830.89
203_R241_E0.5810.89
128_R155_F0.5780.89
145_H200_I0.5770.89
47_Q51_D0.5720.89
157_E162_S0.5700.88
122_T253_E0.5660.88
13_G201_Q0.5660.88
145_H171_H0.5650.88
228_A247_L0.5650.88
67_T103_T0.5630.88
11_A182_L0.5620.88
134_D161_A0.5560.87
251_E264_K0.5530.87
65_F103_T0.5530.87
127_I151_A0.5530.87
10_V13_G0.5530.87
65_F98_C0.5520.87
231_V250_P0.5510.87
112_I115_E0.5510.87
240_R246_R0.5490.86
26_E31_I0.5460.86
132_P159_K0.5440.86
148_K151_A0.5400.86
207_D210_K0.5390.85
142_V197_T0.5390.85
38_Q201_Q0.5360.85
95_K138_K0.5360.85
14_G17_K0.5330.85
123_T234_V0.5320.85
99_R103_T0.5310.85
67_T99_R0.5300.85
99_R145_H0.5300.85
142_V147_E0.5300.85
97_A116_A0.5280.84
202_V242_E0.5270.84
91_I94_A0.5270.84
220_K224_E0.5260.84
186_L191_V0.5250.84
29_G32_P0.5250.84
203_R207_D0.5240.84
19_E73_T0.5230.84
13_G36_P0.5230.84
101_Y254_R0.5220.84
187_M221_V0.5220.84
240_R249_A0.5200.83
30_G263_A0.5190.83
64_I156_L0.5160.83
259_I263_A0.5160.83
201_Q204_S0.5150.83
149_A171_H0.5130.83
21_I102_K0.5120.82
71_L107_L0.5120.82
12_I21_I0.5120.82
66_T70_G0.5110.82
51_D166_I0.5110.82
21_I255_M0.5100.82
143_Q148_K0.5100.82
194_V226_A0.5100.82
114_P117_S0.5100.82
15_S201_Q0.5090.82
125_G128_R0.5090.82
55_F60_A0.5090.82
246_R249_A0.5070.82
128_R224_E0.5060.82
53_R81_I0.5040.81
55_F91_I0.5030.81
27_K80_K0.5030.81
130_L159_K0.5020.81
37_L174_P0.5010.81
145_H168_P0.5000.81
15_S40_T0.5000.81
123_T200_I0.5000.81
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3d8tA 1 0.9259 100 0.151 Contact Map
1wcwA 1 0.9296 100 0.162 Contact Map
3re1A 1 0.9222 100 0.174 Contact Map
1jr2A 1 0.9222 100 0.184 Contact Map
4es6A 1 0.9 100 0.197 Contact Map
3mw8A 1 0.8704 100 0.219 Contact Map
3p9zA 1 0.7889 100 0.298 Contact Map
4rk6A 2 0.8556 97.4 0.865 Contact Map
3clkA 2 0.8481 97.2 0.87 Contact Map
3kkeA 2 0.8926 97.1 0.872 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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