MAO3 - BACSU - GREMLIN Contacts

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MAO3 - Probable NAD-dependent malic enzyme 3

UniProt:	O34389	Sequences: MKQFRVTNEGDIQTTLRGLEVLSVPFLNKGVAFTEEERKELGLKGFLPPKVLTIDDQAKRAYEQYSAQPDDLSKNVYLTALHDRNETLFYRLLNDHLGEMLPIVYTPTVGTAIQRYSHEYRKPRGLYLSIDDPDGMKEAFKQYKDQSDTIDLIVATDAEGILGIGDWGVGGIAISIGKLAVYTAAAGIDPSRVLAVVLDAGTNQESLLNDPLYVGNQHSRVRGERYDQFIDDYVALARETFPNALLHWEDFGAKNARSILKRYKDKVCTFNDDIQGTGAVSLAAVLSCAKASKVPLRDHRVVIFGAGTAGIGIAEQLREALVREGLSEEESYKRFWCIDRNGLLTDDMDQLLDFQKPYARSADEVKDYQRNGDGGGIDLLEVVRQAKPTILIGTSTVSGAFTEEIVKEMASHVKRPAILPMSNPTTLSEAKPEDLIEWTEGRALITTGSPFPPVEYNGVTYHIGQANNALVFPGLGLGTIVTKSKLITDGMFEACARAIAGMVNVGVPGAPMLPKVEDLRTVSATVAVEVAKTAMKEGVATEEPEDIIQAVQDAMWYPVYKPIRAI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	566 (536)
Sequences:	1477 (833)
Seq/√Len:	36.0

ECOLI - MAO1
BACSU - MAO3 MAO2 MAO1 MAO4
SULSO - Q97UX2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
403_E	407_K	8.514	1.00
205_E	209_N	5.955	1.00
224_E	228_Q	4.185	1.00
137_K	239_E	4.089	1.00
65_Y	100_M	4.078	1.00
315_E	358_Y	4.046	1.00
93_L	104_V	4.041	1.00
490_G	537_E	4.021	1.00
151_D	192_R	3.846	1.00
410_A	439_T	3.767	1.00
155_A	233_Y	3.678	1.00
488_T	539_V	3.659	1.00
227_D	258_S	3.551	1.00
406_V	438_W	3.322	1.00
302_V	382_V	3.242	1.00
433_E	437_E	3.224	1.00
378_D	381_E	3.167	1.00
91_R	95_D	3.091	1.00
346_D	361_S	3.001	1.00
134_D	232_D	2.968	1.00
111_T	115_R	2.938	1.00
203_N	222_R	2.920	1.00
410_A	442_R	2.906	1.00
198_L	230_I	2.823	1.00
440_E	457_N	2.791	1.00
264_K	489_D	2.780	1.00
231_D	266_K	2.748	1.00
380_L	404_E	2.706	1.00
205_E	219_S	2.685	1.00
384_R	408_E	2.667	1.00
248_W	269_T	2.621	1.00
430_A	435_L	2.595	1.00
234_V	267_V	2.582	1.00
407_K	440_E	2.560	1.00
61_A	92_L	2.517	1.00
408_E	412_H	2.463	1.00
29_K	37_E	2.404	1.00
68_Q	73_S	2.387	1.00
479_T	487_I	2.386	1.00
327_S	330_E	2.379	1.00
528_V	551_V	2.368	1.00
233_Y	237_A	2.309	0.99
488_T	537_E	2.298	0.99
533_T	537_E	2.296	0.99
524_A	552_Q	2.294	0.99
141_K	240_T	2.235	0.99
408_E	411_S	2.208	0.99
505_V	508_P	2.182	0.99
66_S	99_E	2.158	0.99
278_G	316_Q	2.152	0.99
380_L	405_I	2.129	0.99
340_R	355_Q	2.122	0.99
533_T	536_K	2.087	0.99
71_D	74_K	2.063	0.99
436_I	456_Y	2.046	0.99
304_F	400_A	2.033	0.99
409_M	418_I	2.011	0.98
96_H	99_E	1.993	0.98
326_L	334_R	1.983	0.98
39_K	44_K	1.974	0.98
295_P	298_D	1.966	0.98
86_E	124_R	1.952	0.98
474_G	478_G	1.925	0.98
62_Y	96_H	1.910	0.98
255_N	258_S	1.906	0.98
406_V	418_I	1.899	0.98
471_V	475_L	1.893	0.98
54_I	91_R	1.878	0.98
130_I	221_V	1.867	0.97
70_D	73_S	1.866	0.97
431_K	434_D	1.864	0.97
128_L	136_M	1.857	0.97
53_T	56_D	1.847	0.97
491_M	534_A	1.829	0.97
414_K	442_R	1.826	0.97
313_I	394_T	1.801	0.97
106_T	449_S	1.794	0.97
285_V	317_L	1.777	0.97
444_L	512_M	1.766	0.96
285_V	390_I	1.761	0.96
231_D	262_R	1.755	0.96
131_D	216_N	1.753	0.96
304_F	397_V	1.743	0.96
548_I	552_Q	1.737	0.96
383_V	405_I	1.706	0.96
549_Q	553_D	1.702	0.96
231_D	235_A	1.684	0.95
243_N	483_K	1.680	0.95
351_L	359_A	1.672	0.95
455_E	460_T	1.653	0.95
58_A	91_R	1.651	0.95
208_L	219_S	1.650	0.95
234_V	246_L	1.645	0.95
268_C	479_T	1.614	0.94
136_M	229_F	1.588	0.94
328_E	332_Y	1.582	0.93
204_Q	207_L	1.578	0.93
284_A	513_L	1.574	0.93
297_R	324_E	1.573	0.93
330_E	334_R	1.570	0.93
130_I	229_F	1.568	0.93
546_D	549_Q	1.565	0.93
227_D	255_N	1.565	0.93
153_I	237_A	1.559	0.93
323_R	497_R	1.555	0.93
159_E	255_N	1.550	0.93
62_Y	66_S	1.548	0.93
299_H	389_T	1.547	0.93
380_L	384_R	1.542	0.93
155_A	237_A	1.542	0.93
387_K	412_H	1.541	0.93
98_G	517_E	1.538	0.92
518_D	521_T	1.538	0.92
234_V	248_W	1.534	0.92
302_V	338_I	1.529	0.92
302_V	386_A	1.529	0.92
403_E	438_W	1.528	0.92
160_G	164_I	1.516	0.92
318_R	332_Y	1.514	0.92
58_A	95_D	1.483	0.91
532_K	536_K	1.474	0.91
159_E	203_N	1.472	0.91
246_L	267_V	1.448	0.90
360_R	364_E	1.446	0.90
196_V	233_Y	1.446	0.90
118_H	210_D	1.438	0.90
488_T	533_T	1.430	0.89
152_L	476_G	1.429	0.89
524_A	548_I	1.429	0.89
130_I	216_N	1.429	0.89
478_G	534_A	1.426	0.89
230_I	259_I	1.415	0.89
52_L	60_R	1.415	0.89
406_V	439_T	1.406	0.89
159_E	252_G	1.400	0.88
301_V	321_L	1.400	0.88
62_Y	100_M	1.398	0.88
478_G	482_T	1.396	0.88
44_K	132_D	1.388	0.88
481_V	531_A	1.384	0.88
65_Y	103_I	1.383	0.88
418_I	435_L	1.370	0.87
432_P	445_I	1.369	0.87
488_T	491_M	1.367	0.87
54_I	87_T	1.362	0.87
456_Y	461_Y	1.362	0.87
466_A	513_L	1.352	0.87
335_F	360_R	1.347	0.86
384_R	404_E	1.346	0.86
455_E	458_G	1.346	0.86
31_V	214_V	1.340	0.86
341_N	355_Q	1.338	0.86
218_H	221_V	1.335	0.86
528_V	548_I	1.332	0.86
196_V	229_F	1.320	0.85
532_K	544_P	1.320	0.85
478_G	484_S	1.318	0.85
172_I	197_V	1.300	0.84
403_E	440_E	1.293	0.84
288_C	417_A	1.292	0.84
303_I	314_A	1.281	0.83
478_G	530_V	1.278	0.83
396_T	400_A	1.277	0.83
131_D	218_H	1.277	0.83
62_Y	99_E	1.249	0.82
434_D	437_E	1.247	0.82
436_I	463_I	1.236	0.81
344_L	355_Q	1.235	0.81
245_L	487_I	1.234	0.81
133_P	225_R	1.233	0.81
482_T	531_A	1.232	0.81
430_A	445_I	1.231	0.81
106_T	110_G	1.230	0.81
533_T	539_V	1.224	0.80
380_L	408_E	1.221	0.80
360_R	386_A	1.219	0.80
340_R	344_L	1.210	0.80
440_E	456_Y	1.209	0.80
62_Y	92_L	1.207	0.79
125_G	172_I	1.205	0.79
484_S	491_M	1.204	0.79
113_I	164_I	1.203	0.79
85_N	560_Y	1.195	0.79
321_L	326_L	1.189	0.78
79_T	89_F	1.178	0.78
238_R	267_V	1.173	0.78
224_E	227_D	1.170	0.77
406_V	435_L	1.170	0.77
280_V	499_I	1.166	0.77
188_I	477_L	1.165	0.77
525_T	548_I	1.160	0.77
21_V	41_L	1.157	0.77
436_I	461_Y	1.157	0.77
136_M	140_F	1.156	0.76
333_K	361_S	1.155	0.76
399_G	434_D	1.149	0.76
156_T	197_V	1.149	0.76
407_K	442_R	1.148	0.76
285_V	301_V	1.138	0.75
338_I	379_L	1.137	0.75
111_T	114_Q	1.135	0.75
81_L	109_V	1.130	0.75
110_G	472_F	1.123	0.74
198_L	229_F	1.123	0.74
133_P	232_D	1.116	0.74
113_I	161_I	1.116	0.74
36_E	40_E	1.114	0.74
300_R	389_T	1.111	0.74
405_I	408_E	1.101	0.73
18_G	21_V	1.100	0.73
336_W	386_A	1.099	0.73
284_A	419_L	1.098	0.73
257_R	355_Q	1.098	0.73
82_H	124_R	1.097	0.73
137_K	240_T	1.093	0.72
94_N	520_R	1.087	0.72
387_K	411_S	1.085	0.72
106_T	472_F	1.083	0.72
338_I	382_V	1.080	0.71
61_A	77_Y	1.074	0.71
133_P	228_Q	1.074	0.71
280_V	526_V	1.073	0.71
222_R	255_N	1.065	0.70
137_K	232_D	1.065	0.70
379_L	391_L	1.057	0.70
501_G	529_E	1.053	0.69
237_A	244_A	1.043	0.69
83_D	122_K	1.041	0.69
300_R	386_A	1.033	0.68
315_E	357_P	1.033	0.68
128_L	140_F	1.032	0.68
436_I	441_G	1.032	0.68
543_E	547_I	1.030	0.68
116_Y	176_I	1.027	0.67
231_D	263_Y	1.021	0.67
321_L	334_R	1.017	0.67
453_P	462_H	1.017	0.67
381_E	384_R	1.014	0.66
72_L	119_E	1.014	0.66
238_R	246_L	1.014	0.66
265_D	486_L	1.006	0.66
188_I	480_I	1.005	0.66
113_I	160_G	1.002	0.66
185_A	394_T	1.000	0.65
16_L	21_V	0.998	0.65
494_A	529_E	0.997	0.65
347_D	362_A	0.994	0.65
284_A	464_G	0.990	0.65
235_A	266_K	0.990	0.65
50_K	217_Q	0.983	0.64
164_I	167_W	0.977	0.64
524_A	528_V	0.976	0.63
471_V	499_I	0.972	0.63
524_A	555_M	0.970	0.63
430_A	447_T	0.970	0.63
236_L	240_T	0.970	0.63
82_H	86_E	0.969	0.63
28_N	33_F	0.966	0.63
29_K	561_K	0.965	0.63
113_I	173_A	0.963	0.62
330_E	333_K	0.963	0.62
252_G	308_T	0.962	0.62
158_A	197_V	0.962	0.62
55_D	457_N	0.960	0.62
344_L	359_A	0.959	0.62
253_A	308_T	0.958	0.62
140_F	240_T	0.954	0.62
475_L	492_F	0.951	0.61
335_F	382_V	0.948	0.61
543_E	546_D	0.945	0.61
21_V	43_L	0.945	0.61
137_K	141_K	0.944	0.61
499_I	526_V	0.943	0.61
186_A	252_G	0.943	0.61
130_I	136_M	0.943	0.61
381_E	385_Q	0.942	0.61
203_N	219_S	0.940	0.60
92_L	100_M	0.937	0.60
498_A	525_T	0.936	0.60
177_G	184_A	0.933	0.60
516_V	526_V	0.931	0.60
50_K	56_D	0.930	0.60
322_V	328_E	0.927	0.59
208_L	217_Q	0.923	0.59
109_V	177_G	0.923	0.59
483_K	541_T	0.922	0.59
321_L	325_G	0.922	0.59
79_T	82_H	0.920	0.59
520_R	555_M	0.911	0.58
81_L	84_R	0.911	0.58
32_A	560_Y	0.906	0.58
504_N	507_V	0.906	0.58
80_A	84_R	0.905	0.58
318_R	322_V	0.903	0.57
106_T	280_V	0.902	0.57
66_S	96_H	0.902	0.57
346_D	359_A	0.900	0.57
159_E	222_R	0.899	0.57
83_D	124_R	0.897	0.57
106_T	451_F	0.893	0.57
348_M	355_Q	0.891	0.56
311_I	337_C	0.891	0.56
205_E	208_L	0.890	0.56
152_L	182_Y	0.889	0.56
341_N	344_L	0.889	0.56
69_P	73_S	0.888	0.56
281_S	344_L	0.885	0.56
47_L	51_V	0.885	0.56
346_D	362_A	0.880	0.55
404_E	408_E	0.875	0.55
154_V	247_H	0.874	0.55
439_T	522_V	0.870	0.55
435_L	445_I	0.866	0.54
111_T	426_T	0.866	0.54
76_V	121_R	0.864	0.54
481_V	550_A	0.863	0.54
377_I	382_V	0.859	0.54
432_P	447_T	0.857	0.53
160_G	173_A	0.856	0.53
483_K	542_E	0.854	0.53
302_V	405_I	0.846	0.52
535_M	544_P	0.843	0.52
403_E	439_T	0.840	0.52
68_Q	76_V	0.840	0.52
447_T	463_I	0.839	0.52
76_V	119_E	0.838	0.52
109_V	172_I	0.836	0.52
407_K	439_T	0.833	0.51
319_E	328_E	0.833	0.51
149_T	192_R	0.830	0.51
128_L	139_A	0.830	0.51
547_I	551_V	0.830	0.51
296_L	321_L	0.828	0.51
132_D	135_G	0.828	0.51
117_S	208_L	0.823	0.50
425_T	450_P	0.823	0.50
388_P	409_M	0.822	0.50
189_D	192_R	0.821	0.50
329_E	333_K	0.819	0.50
70_D	111_T	0.818	0.50
230_I	269_T	0.816	0.50
304_F	379_L	0.816	0.50
177_G	182_Y	0.814	0.50
52_L	84_R	0.812	0.50
257_R	354_F	0.811	0.49
228_Q	404_E	0.810	0.49
196_V	237_A	0.810	0.49
113_I	470_L	0.809	0.49
123_P	419_L	0.808	0.49
298_D	330_E	0.806	0.49
430_A	556_W	0.803	0.49
169_V	230_I	0.802	0.49
490_G	533_T	0.802	0.49
486_L	539_V	0.801	0.49
30_G	122_K	0.801	0.49
203_N	206_S	0.801	0.49
114_Q	426_T	0.800	0.48
16_L	24_V	0.797	0.48
252_G	255_N	0.794	0.48
160_G	470_L	0.793	0.48
410_A	413_V	0.792	0.48
320_A	324_E	0.792	0.48
403_E	437_E	0.791	0.48
159_E	394_T	0.788	0.47
136_M	232_D	0.785	0.47
46_F	142_Q	0.784	0.47
297_R	326_L	0.781	0.47
257_R	358_Y	0.779	0.47
382_V	386_A	0.778	0.47
118_H	212_L	0.778	0.47
420_P	438_W	0.772	0.46
340_R	396_T	0.771	0.46
417_A	446_T	0.770	0.46
300_R	388_P	0.770	0.46
63_E	66_S	0.769	0.46
421_M	451_F	0.768	0.46
303_I	392_I	0.766	0.46
301_V	317_L	0.765	0.45
52_L	77_Y	0.765	0.45
403_E	406_V	0.764	0.45
248_W	267_V	0.762	0.45
549_Q	552_Q	0.761	0.45
290_K	501_G	0.760	0.45
336_W	360_R	0.759	0.45
113_I	278_G	0.757	0.45
31_V	558_P	0.757	0.45
177_G	465_Q	0.755	0.45
33_F	37_E	0.753	0.44
76_V	526_V	0.753	0.44
164_I	173_A	0.750	0.44
253_A	355_Q	0.749	0.44
402_T	405_I	0.749	0.44
531_A	535_M	0.749	0.44
519_L	526_V	0.748	0.44
160_G	175_S	0.748	0.44
202_T	208_L	0.746	0.44
60_R	446_T	0.745	0.44
179_L	464_G	0.743	0.44
248_W	470_L	0.742	0.43
464_G	513_L	0.739	0.43
197_V	344_L	0.736	0.43
176_I	322_V	0.735	0.43
464_G	503_V	0.735	0.43
345_T	365_V	0.734	0.43
428_S	451_F	0.733	0.43
137_K	236_L	0.733	0.43
395_S	400_A	0.733	0.43
481_V	554_A	0.732	0.43
29_K	33_F	0.732	0.43
291_A	415_R	0.731	0.43
32_A	53_T	0.730	0.42
294_V	299_H	0.730	0.42
502_M	525_T	0.730	0.42
498_A	502_M	0.729	0.42
459_V	509_G	0.727	0.42
122_K	415_R	0.725	0.42
534_A	539_V	0.725	0.42
535_M	540_A	0.725	0.42
43_L	47_L	0.724	0.42
75_N	316_Q	0.724	0.42
310_G	512_M	0.722	0.42
185_A	516_V	0.722	0.42
44_K	135_G	0.721	0.42
270_F	450_P	0.720	0.42
169_V	214_V	0.719	0.42
388_P	412_H	0.718	0.41
322_V	326_L	0.717	0.41
63_E	118_H	0.717	0.41
98_G	515_K	0.715	0.41
227_D	230_I	0.714	0.41
550_A	554_A	0.713	0.41
257_R	274_I	0.713	0.41
270_F	449_S	0.712	0.41
51_V	443_A	0.711	0.41
398_S	402_T	0.711	0.41
74_K	99_E	0.711	0.41
68_Q	77_Y	0.710	0.41
226_Y	252_G	0.709	0.41
281_S	466_A	0.707	0.41
319_E	322_V	0.707	0.41
435_L	447_T	0.706	0.40
425_T	453_P	0.706	0.40
522_V	526_V	0.705	0.40
87_T	310_G	0.705	0.40
245_L	268_C	0.704	0.40
34_T	37_E	0.703	0.40
353_D	356_K	0.702	0.40
345_T	362_A	0.702	0.40
498_A	526_V	0.701	0.40
112_A	125_G	0.697	0.40
485_K	541_T	0.696	0.40
174_I	423_N	0.696	0.40
517_E	536_K	0.696	0.40
159_E	226_Y	0.695	0.40
340_R	397_V	0.695	0.40
181_V	247_H	0.694	0.39
117_S	170_G	0.693	0.39
394_T	470_L	0.693	0.39
289_A	294_V	0.692	0.39
109_V	164_I	0.692	0.39
113_I	175_S	0.691	0.39
242_P	558_P	0.690	0.39
310_G	394_T	0.690	0.39
152_L	245_L	0.689	0.39
302_V	360_R	0.689	0.39
126_L	143_Y	0.688	0.39
484_S	487_I	0.687	0.39
17_R	42_G	0.687	0.39
129_S	229_F	0.687	0.39
86_E	278_G	0.687	0.39
502_M	518_D	0.687	0.39
289_A	295_P	0.686	0.39
453_P	460_T	0.685	0.39
181_V	269_T	0.684	0.39
268_C	278_G	0.684	0.39
247_H	466_A	0.678	0.38
221_V	229_F	0.678	0.38
380_L	383_V	0.678	0.38
159_E	469_A	0.676	0.38
150_I	240_T	0.674	0.38
341_N	348_M	0.673	0.38
335_F	389_T	0.672	0.38
340_R	348_M	0.672	0.38
74_K	103_I	0.671	0.38
477_L	555_M	0.670	0.37
239_E	407_K	0.668	0.37
406_V	434_D	0.667	0.37
451_F	472_F	0.667	0.37
57_Q	88_L	0.667	0.37
58_A	92_L	0.667	0.37
257_R	308_T	0.667	0.37
106_T	396_T	0.666	0.37
519_L	523_S	0.666	0.37
55_D	95_D	0.663	0.37
91_R	559_V	0.663	0.37
285_V	419_L	0.663	0.37
100_M	103_I	0.661	0.37
180_A	526_V	0.661	0.37
484_S	530_V	0.661	0.37
324_E	497_R	0.658	0.36
75_N	278_G	0.656	0.36
68_Q	469_A	0.656	0.36
431_K	445_I	0.655	0.36
130_I	133_P	0.655	0.36
164_I	470_L	0.655	0.36
396_T	427_L	0.655	0.36
31_V	52_L	0.653	0.36
172_I	175_S	0.653	0.36
200_A	226_Y	0.652	0.36
208_L	218_H	0.652	0.36
164_I	394_T	0.651	0.36
497_R	501_G	0.651	0.36
285_V	289_A	0.650	0.36
407_K	438_W	0.648	0.36
90_Y	418_I	0.647	0.36
51_V	70_D	0.647	0.36
113_I	394_T	0.647	0.36
252_G	469_A	0.646	0.36
355_Q	513_L	0.645	0.35
208_L	453_P	0.644	0.35
484_S	539_V	0.643	0.35
77_Y	120_Y	0.641	0.35
306_A	337_C	0.640	0.35
327_S	508_P	0.639	0.35
524_A	551_V	0.639	0.35
124_R	268_C	0.638	0.35
227_D	231_D	0.638	0.35
403_E	434_D	0.637	0.35
86_E	121_R	0.637	0.35
113_I	158_A	0.637	0.35
435_L	556_W	0.636	0.35
184_A	466_A	0.635	0.35
453_P	486_L	0.635	0.35
115_R	118_H	0.634	0.35
488_T	534_A	0.634	0.35
378_D	382_V	0.634	0.35
449_S	523_S	0.634	0.35
428_S	431_K	0.633	0.34
223_G	255_N	0.633	0.34
89_F	93_L	0.632	0.34
228_Q	232_D	0.632	0.34
204_Q	209_N	0.631	0.34
134_D	198_L	0.631	0.34
112_A	446_T	0.631	0.34
144_K	232_D	0.631	0.34
412_H	439_T	0.630	0.34
57_Q	85_N	0.629	0.34
106_T	274_I	0.629	0.34
304_F	338_I	0.629	0.34
225_R	228_Q	0.629	0.34
430_A	434_D	0.628	0.34
255_N	469_A	0.628	0.34
71_D	111_T	0.627	0.34
25_P	28_N	0.626	0.34
333_K	437_E	0.626	0.34
387_K	435_L	0.626	0.34
439_T	443_A	0.626	0.34
196_V	230_I	0.624	0.34
420_P	526_V	0.624	0.34
333_K	383_V	0.622	0.34
391_L	474_G	0.622	0.34
72_L	76_V	0.622	0.34
278_G	394_T	0.621	0.34
17_R	21_V	0.621	0.34
322_V	549_Q	0.621	0.34
520_R	557_Y	0.619	0.33
474_G	534_A	0.619	0.33
318_R	359_A	0.616	0.33
22_L	47_L	0.616	0.33
389_T	413_V	0.615	0.33
248_W	259_I	0.615	0.33
113_I	167_W	0.614	0.33
445_I	454_V	0.613	0.33
152_L	164_I	0.612	0.33
247_H	470_L	0.611	0.33
410_A	440_E	0.610	0.33
281_S	421_M	0.610	0.33
322_V	325_G	0.610	0.33
116_Y	313_I	0.609	0.33
155_A	204_Q	0.608	0.33
181_V	248_W	0.607	0.32
408_E	413_V	0.607	0.32
410_A	414_K	0.607	0.32
185_A	313_I	0.607	0.32
319_E	332_Y	0.607	0.32
135_G	138_E	0.606	0.32
152_L	181_V	0.606	0.32
532_K	535_M	0.605	0.32
198_L	294_V	0.605	0.32
327_S	333_K	0.604	0.32
160_G	394_T	0.604	0.32
160_G	181_V	0.604	0.32
31_V	81_L	0.604	0.32
469_A	551_V	0.603	0.32
248_W	303_I	0.603	0.32
193_V	247_H	0.603	0.32
55_D	521_T	0.603	0.32
402_T	434_D	0.602	0.32
245_L	475_L	0.602	0.32
113_I	247_H	0.601	0.32
54_I	58_A	0.601	0.32
173_A	471_V	0.600	0.32
89_F	180_A	0.599	0.32
159_E	513_L	0.599	0.32
470_L	526_V	0.597	0.32
133_P	236_L	0.597	0.32
164_I	175_S	0.593	0.31
141_K	217_Q	0.593	0.31
89_F	488_T	0.593	0.31
113_I	152_L	0.593	0.31
65_Y	92_L	0.592	0.31
35_E	39_K	0.590	0.31
248_W	337_C	0.590	0.31
109_V	247_H	0.588	0.31
38_R	47_L	0.588	0.31
247_H	270_F	0.586	0.31
159_E	313_I	0.585	0.31
313_I	469_A	0.584	0.31
115_R	266_K	0.584	0.31
177_G	466_A	0.583	0.31
129_S	132_D	0.583	0.31
244_A	259_I	0.583	0.31
248_W	380_L	0.582	0.31
315_E	332_Y	0.582	0.31
83_D	121_R	0.581	0.31
68_Q	80_A	0.581	0.31
128_L	138_E	0.581	0.31
309_A	423_N	0.581	0.31
420_P	436_I	0.581	0.31
223_G	226_Y	0.580	0.30
37_E	57_Q	0.580	0.30
353_D	395_S	0.580	0.30
274_I	308_T	0.579	0.30
20_E	24_V	0.579	0.30
225_R	333_K	0.579	0.30
24_V	27_L	0.578	0.30
387_K	485_K	0.578	0.30
421_M	428_S	0.577	0.30
316_Q	492_F	0.577	0.30
535_M	542_E	0.574	0.30
470_L	516_V	0.573	0.30
110_G	156_T	0.573	0.30
116_Y	180_A	0.572	0.30
293_K	407_K	0.571	0.30
116_Y	282_L	0.571	0.30
127_Y	151_D	0.571	0.30
183_T	453_P	0.570	0.30
487_I	530_V	0.570	0.30
449_S	472_F	0.569	0.30
333_K	360_R	0.569	0.30
428_S	435_L	0.569	0.30
284_A	291_A	0.568	0.30
160_G	253_A	0.568	0.30
138_E	459_V	0.568	0.30
155_A	198_L	0.568	0.30
248_W	306_A	0.568	0.30
52_L	116_Y	0.567	0.29
257_R	315_E	0.566	0.29
498_A	527_A	0.565	0.29
432_P	451_F	0.565	0.29
253_A	352_L	0.565	0.29
516_V	519_L	0.564	0.29
175_S	197_V	0.564	0.29
528_V	532_K	0.563	0.29
39_K	138_E	0.563	0.29
350_Q	474_G	0.563	0.29
383_V	433_E	0.562	0.29
59_K	63_E	0.562	0.29
529_E	532_K	0.562	0.29
341_N	397_V	0.561	0.29
291_A	444_L	0.561	0.29
491_M	537_E	0.561	0.29
87_T	560_Y	0.561	0.29
499_I	529_E	0.561	0.29
301_V	390_I	0.560	0.29
262_R	302_V	0.560	0.29
398_S	434_D	0.560	0.29
330_E	433_E	0.559	0.29
436_I	443_A	0.559	0.29
294_V	389_T	0.559	0.29
179_L	193_V	0.559	0.29
292_S	295_P	0.558	0.29
491_M	526_V	0.557	0.29
390_I	417_A	0.557	0.29
337_C	344_L	0.557	0.29
325_G	331_S	0.555	0.29
362_A	365_V	0.555	0.29
130_I	551_V	0.555	0.29
226_Y	255_N	0.553	0.28
169_V	492_F	0.553	0.28
106_T	426_T	0.551	0.28
146_Q	240_T	0.551	0.28
117_S	475_L	0.551	0.28
125_G	451_F	0.551	0.28
381_E	404_E	0.550	0.28
97_L	559_V	0.549	0.28
507_V	510_A	0.549	0.28
423_N	450_P	0.549	0.28
222_R	225_R	0.548	0.28
356_K	545_E	0.548	0.28
56_D	73_S	0.547	0.28
304_F	396_T	0.546	0.28
117_S	492_F	0.545	0.28
90_Y	224_E	0.543	0.28
319_E	489_D	0.542	0.28
90_Y	176_I	0.541	0.28
293_K	333_K	0.541	0.28
17_R	41_L	0.541	0.28
516_V	523_S	0.540	0.28
251_F	450_P	0.540	0.28
32_A	57_Q	0.540	0.28
203_N	316_Q	0.539	0.28
45_G	142_Q	0.537	0.27
494_A	533_T	0.536	0.27
60_R	300_R	0.536	0.27
254_K	258_S	0.536	0.27
502_M	522_V	0.536	0.27
130_I	198_L	0.535	0.27
18_G	74_K	0.535	0.27
132_D	240_T	0.535	0.27
90_Y	261_K	0.534	0.27
143_Y	232_D	0.533	0.27
464_G	470_L	0.533	0.27
264_K	419_L	0.532	0.27
282_L	320_A	0.532	0.27
143_Y	556_W	0.532	0.27
535_M	547_I	0.532	0.27
286_L	497_R	0.531	0.27
484_S	531_A	0.531	0.27
346_D	356_K	0.531	0.27
521_T	524_A	0.529	0.27
253_A	470_L	0.529	0.27
396_T	421_M	0.529	0.27
436_I	454_V	0.528	0.27
322_V	331_S	0.528	0.27
90_Y	485_K	0.527	0.27
114_Q	170_G	0.527	0.27
85_N	88_L	0.527	0.27
68_Q	71_D	0.527	0.27
151_D	554_A	0.527	0.27
116_Y	172_I	0.527	0.27
538_G	551_V	0.527	0.27
60_R	212_L	0.526	0.27
106_T	450_P	0.526	0.27
35_E	44_K	0.526	0.27
204_Q	340_R	0.525	0.27
76_V	218_H	0.525	0.27
17_R	20_E	0.524	0.26
492_F	495_C	0.524	0.26
131_D	225_R	0.524	0.26
56_D	217_Q	0.523	0.26
115_R	419_L	0.523	0.26
378_D	405_I	0.522	0.26
430_A	463_I	0.521	0.26
498_A	501_G	0.520	0.26
322_V	327_S	0.520	0.26
55_D	553_D	0.520	0.26
288_C	419_L	0.520	0.26
109_V	245_L	0.520	0.26
55_D	243_N	0.520	0.26
420_P	430_A	0.519	0.26
55_D	59_K	0.518	0.26
95_D	99_E	0.518	0.26
106_T	270_F	0.518	0.26
259_I	470_L	0.518	0.26
314_A	335_F	0.517	0.26
310_G	395_S	0.517	0.26
423_N	468_N	0.516	0.26
135_G	437_E	0.516	0.26
212_L	529_E	0.516	0.26
479_T	482_T	0.515	0.26
408_E	444_L	0.514	0.26
396_T	417_A	0.514	0.26
99_E	478_G	0.514	0.26
66_S	100_M	0.512	0.26
106_T	423_N	0.512	0.26
206_S	383_V	0.511	0.26
530_V	534_A	0.510	0.26
536_K	539_V	0.510	0.26
52_L	64_Q	0.510	0.26
491_M	533_T	0.508	0.25
81_L	212_L	0.508	0.25
323_R	490_G	0.507	0.25
146_Q	241_F	0.507	0.25
35_E	51_V	0.507	0.25
252_G	258_S	0.507	0.25
287_S	512_M	0.506	0.25
303_I	337_C	0.506	0.25
338_I	405_I	0.504	0.25
228_Q	381_E	0.504	0.25
59_K	211_P	0.504	0.25
293_K	505_V	0.503	0.25
67_A	111_T	0.502	0.25
220_R	226_Y	0.502	0.25
181_V	470_L	0.502	0.25
24_V	39_K	0.502	0.25
146_Q	402_T	0.502	0.25
226_Y	251_F	0.501	0.25
162_L	174_I	0.501	0.25
450_P	523_S	0.501	0.25
406_V	443_A	0.501	0.25
300_R	334_R	0.500	0.25
114_Q	472_F	0.500	0.25
109_V	113_I	0.500	0.25

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1o0sA	4	0.977	100	0.147	Contact Map
1gq2A	6	0.9505	100	0.148	Contact Map
1pj3A	4	0.9576	100	0.152	Contact Map
3nv9A	2	0.788	100	0.537	Contact Map
1vl6A	4	0.6466	100	0.605	Contact Map
2a9fA	2	0.6643	100	0.662	Contact Map
2dvmA	2	0.7191	100	0.667	Contact Map
4ppmA	2	0.0353	99.4	0.944	Contact Map
1v8bA	4	0.735	98.9	0.955	Contact Map
3k92A	5	0.6502	98.1	0.964	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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