O16G2 - BACSU - GREMLIN Contacts

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O16G2 - Probable oligo-1,6-glucosidase 2

UniProt:	O34364	Sequences: MKTDWWKDAVVYQIYPRSFQDSNGDGIGDLRGIISRLDYIKELGADVIWICPIYPSPNVDYGYDVTNHKAIMDSYGTMDDFHELLDQVHQRGLKLVMDFVLNHTSVEHPWFKEAELDKNSKYRSYYYWRPGTKNGPPTDWLSNYGCPVWQYEEHTGEYYLHMNAVKQADLNWENPEVRQAVYDMMKFWLDKGVDGLRIDQLHLISKKEYLPSYEDYINQQAEPKPFQPNGERIHDYLKEITDEVFSHYDVMSVGEVGSVTPEEGLKYTGTDKHELNMIFHFQHMELDQQPGKEHWDLKPLELSDLKSVLTKWQKKLEHQGWNTLFWCNHDQPRIVSRFGDDGEYRKASAKMLAAVIYFMKGTPYIYQGEEIGMTNAPFTRIEDYKDIQTINMYHKRVFEKGYDPNDVMRSILAKSRDHARTPMQWNSGKNAGFTDGTPWLKVNPNFTAINVEEAQGDPDSVLNYYKKLISLRKQYADLMKGSFDLLLPDDPQLFVYMRENSKQQLLSVNNFSKEQAVFQWPKNCGKAQASLLLSNYNNDDLDDEMVFRPYESRVYLLDKTN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	561 (486)
Sequences:	9336 (6327)
Seq/√Len:	287.0

ECOLI - TREC SUCP MALZ GLGX AMY2 YGAQ GLGB AMY1
BACSU - O16G2 O16G3 O16G1 TREC BBMA GLGB PULA AMY
SULSO - TREZ Q7LX99

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
38_D	91_R	5.001	1.00
20_Q	36_R	4.844	1.00
82_H	191_K	4.631	1.00
130_P	157_E	4.508	1.00
89_H	194_D	4.276	1.00
31_R	83_E	4.160	1.00
87_Q	90_Q	4.105	1.00
55_P	70_A	3.942	1.00
104_T	126_Y	3.720	1.00
87_Q	91_R	3.477	1.00
40_I	45_A	3.206	1.00
31_R	34_I	3.132	1.00
20_Q	35_S	3.119	1.00
55_P	66_T	3.079	1.00
88_V	93_L	3.072	1.00
88_V	95_L	3.057	1.00
354_A	464_Y	2.975	1.00
178_R	239_E	2.872	1.00
34_I	87_Q	2.753	1.00
354_A	552_S	2.701	1.00
150_Q	165_V	2.694	1.00
77_T	80_D	2.670	1.00
234_H	274_E	2.587	1.00
327_C	369_E	2.468	1.00
463_N	466_K	2.459	1.00
31_R	80_D	2.426	1.00
81_F	85_L	2.414	1.00
123_R	155_T	2.317	1.00
484_D	497_M	2.317	1.00
59_V	166_K	2.301	1.00
109_P	113_E	2.298	1.00
14_I	33_I	2.283	1.00
37_L	91_R	2.265	1.00
371_I	451_V	2.254	1.00
107_E	166_K	2.251	1.00
69_K	183_D	2.212	1.00
42_E	466_K	2.197	1.00
34_I	83_E	2.180	1.00
83_E	87_Q	2.169	1.00
497_M	504_Q	2.161	1.00
351_M	509_N	2.155	1.00
115_E	152_E	2.140	1.00
78_M	191_K	2.126	1.00
41_K	91_R	2.117	1.00
151_Y	156_G	2.055	1.00
9_A	46_D	2.043	1.00
470_S	474_Q	2.041	1.00
499_E	504_Q	2.031	1.00
548_R	551_E	2.024	1.00
33_I	84_L	2.012	1.00
358_F	554_V	1.994	1.00
180_A	183_D	1.983	1.00
232_R	235_D	1.971	1.00
104_T	170_L	1.968	1.00
101_L	181_V	1.953	1.00
24_G	435_D	1.921	1.00
484_D	499_E	1.910	1.00
46_D	473_K	1.908	1.00
353_A	465_Y	1.888	1.00
37_L	88_V	1.880	1.00
495_V	508_V	1.873	1.00
125_Y	180_A	1.869	1.00
186_K	190_D	1.868	1.00
59_V	164_A	1.852	1.00
482_S	499_E	1.836	1.00
355_V	509_N	1.801	1.00
182_Y	239_E	1.800	1.00
358_F	496_Y	1.792	1.00
113_E	120_S	1.777	1.00
372_G	461_V	1.771	1.00
456_G	463_N	1.770	1.00
152_E	155_T	1.759	1.00
185_M	240_I	1.752	1.00
335_V	349_A	1.752	1.00
427_S	452_E	1.713	1.00
48_I	88_V	1.712	1.00
455_Q	462_L	1.709	1.00
186_K	243_E	1.685	1.00
346_K	350_K	1.675	1.00
10_V	469_I	1.668	1.00
531_L	534_S	1.666	1.00
79_D	82_H	1.663	1.00
517_V	544_E	1.653	1.00
86_D	90_Q	1.645	1.00
497_M	506_L	1.642	1.00
179_Q	183_D	1.640	1.00
42_E	455_Q	1.631	1.00
113_E	122_Y	1.624	1.00
173_E	232_R	1.624	1.00
517_V	546_V	1.622	1.00
53_I	97_M	1.622	1.00
11_V	47_V	1.603	1.00
70_A	78_M	1.600	1.00
189_L	250_V	1.593	1.00
67_N	70_A	1.582	1.00
8_D	480_K	1.576	1.00
106_V	166_K	1.560	1.00
27_I	74_S	1.560	1.00
354_A	468_L	1.559	1.00
492_Q	512_S	1.551	1.00
31_R	35_S	1.547	1.00
121_K	176_E	1.539	1.00
55_P	67_N	1.538	1.00
307_S	311_K	1.529	1.00
42_E	462_L	1.521	1.00
81_F	97_M	1.521	1.00
241_T	245_F	1.509	1.00
53_I	71_I	1.494	1.00
179_Q	243_E	1.494	1.00
122_Y	125_Y	1.479	1.00
69_K	187_F	1.475	1.00
350_K	464_Y	1.469	1.00
430_N	436_G	1.457	1.00
462_L	466_K	1.455	1.00
69_K	184_M	1.434	1.00
55_P	73_D	1.424	1.00
310_T	483_F	1.424	1.00
58_N	72_M	1.415	1.00
515_Q	546_V	1.409	1.00
426_N	452_E	1.403	1.00
374_T	445_N	1.401	1.00
53_I	81_F	1.401	1.00
451_V	462_L	1.392	1.00
180_A	184_M	1.392	1.00
107_E	112_K	1.382	1.00
112_K	115_E	1.379	1.00
455_Q	463_N	1.376	1.00
475_Y	503_Q	1.375	1.00
69_K	180_A	1.373	1.00
109_P	112_K	1.369	1.00
466_K	470_S	1.367	1.00
423_M	451_V	1.358	1.00
496_Y	507_S	1.353	1.00
54_Y	97_M	1.352	1.00
454_A	463_N	1.351	1.00
123_R	152_E	1.342	1.00
34_I	84_L	1.339	1.00
59_V	107_E	1.335	1.00
8_D	479_M	1.332	1.00
467_K	470_S	1.331	1.00
33_I	50_I	1.330	1.00
519_Q	544_E	1.328	1.00
430_N	434_T	1.327	1.00
326_W	352_L	1.322	1.00
509_N	552_S	1.320	1.00
238_K	274_E	1.309	1.00
13_Q	51_C	1.305	1.00
104_T	177_V	1.305	1.00
531_L	553_R	1.304	1.00
358_F	478_L	1.297	1.00
85_L	95_L	1.296	1.00
327_C	334_I	1.296	1.00
232_R	236_Y	1.289	1.00
9_A	47_V	1.273	1.00
357_Y	469_I	1.271	1.00
117_D	120_S	1.267	1.00
334_I	338_F	1.254	1.00
176_E	179_Q	1.246	1.00
346_K	457_D	1.239	1.00
536_Y	548_R	1.230	1.00
106_V	168_A	1.221	1.00
351_M	511_F	1.221	1.00
310_T	314_K	1.202	1.00
96_V	195_G	1.202	1.00
373_M	424_Q	1.200	1.00
99_F	185_M	1.196	1.00
30_L	53_I	1.195	1.00
480_K	500_N	1.195	1.00
101_L	185_M	1.190	1.00
457_D	463_N	1.188	1.00
175_P	179_Q	1.187	1.00
50_I	53_I	1.182	1.00
492_Q	516_A	1.181	1.00
114_A	155_T	1.180	1.00
172_W	181_V	1.177	1.00
14_I	40_I	1.175	1.00
71_I	81_F	1.175	1.00
321_W	362_T	1.174	1.00
153_E	156_G	1.173	1.00
349_A	461_V	1.169	1.00
96_V	251_M	1.164	1.00
41_K	93_L	1.162	1.00
477_D	505_L	1.151	1.00
17_R	74_S	1.144	1.00
16_P	33_I	1.144	1.00
58_N	74_S	1.143	1.00
238_K	273_H	1.142	1.00
114_A	128_W	1.141	1.00
477_D	503_Q	1.139	1.00
238_K	242_D	1.134	1.00
30_L	71_I	1.128	1.00
304_D	307_S	1.121	1.00
82_H	86_D	1.121	1.00
182_Y	243_E	1.120	1.00
477_D	500_N	1.110	1.00
263_E	266_K	1.109	1.00
179_Q	182_Y	1.105	1.00
80_D	83_E	1.104	1.00
441_K	444_P	1.098	1.00
475_Y	505_L	1.098	1.00
124_S	174_N	1.098	1.00
131_G	151_Y	1.097	1.00
40_I	48_I	1.093	1.00
101_L	198_I	1.090	1.00
81_F	193_V	1.085	1.00
21_D	26_G	1.084	1.00
243_E	246_S	1.075	1.00
118_K	157_E	1.071	1.00
310_T	485_L	1.066	1.00
117_D	155_T	1.060	1.00
163_N	203_L	1.059	1.00
55_P	72_M	1.059	1.00
113_E	117_D	1.058	1.00
358_F	468_L	1.058	1.00
538_N	548_R	1.052	1.00
120_S	123_R	1.050	1.00
84_L	95_L	1.039	1.00
241_T	246_S	1.030	1.00
178_R	236_Y	1.030	1.00
34_I	38_D	1.022	1.00
531_L	535_N	1.016	1.00
31_R	77_T	1.015	1.00
344_Y	347_A	1.014	1.00
30_L	81_F	1.011	1.00
36_R	39_Y	1.010	1.00
253_V	364_Y	1.009	1.00
30_L	80_D	1.008	1.00
350_K	461_V	1.007	1.00
205_S	232_R	1.004	1.00
131_G	136_P	1.001	1.00
303_S	307_S	0.996	1.00
420_R	423_M	0.996	1.00
301_E	304_D	0.994	1.00
512_S	516_A	0.989	1.00
505_L	532_L	0.988	1.00
113_E	121_K	0.988	1.00
205_S	230_G	0.987	1.00
420_R	424_Q	0.984	1.00
125_Y	176_E	0.984	1.00
332_P	336_S	0.979	1.00
190_D	247_H	0.976	1.00
365_I	465_Y	0.975	1.00
97_M	193_V	0.964	1.00
339_G	348_S	0.961	1.00
29_D	32_G	0.961	1.00
358_F	507_S	0.960	1.00
147_P	150_Q	0.958	1.00
118_K	130_P	0.955	1.00
492_Q	514_E	0.954	1.00
306_K	310_T	0.952	1.00
184_M	187_F	0.951	1.00
57_P	66_T	0.951	1.00
200_Q	203_L	0.950	1.00
187_F	191_K	0.949	1.00
201_L	204_I	0.948	1.00
38_D	87_Q	0.945	1.00
478_L	505_L	0.943	1.00
486_L	506_L	0.943	1.00
508_V	553_R	0.940	1.00
142_S	146_C	0.938	1.00
490_D	516_A	0.936	1.00
531_L	536_Y	0.936	1.00
136_P	147_P	0.935	1.00
47_V	94_K	0.930	1.00
173_E	236_Y	0.925	1.00
78_M	82_H	0.923	1.00
78_M	187_F	0.916	1.00
94_K	194_D	0.912	1.00
452_E	456_G	0.909	1.00
37_L	87_Q	0.909	1.00
23_N	27_I	0.909	1.00
237_L	240_I	0.907	1.00
229_N	263_E	0.904	1.00
41_K	92_G	0.904	1.00
201_L	237_L	0.902	1.00
16_P	51_C	0.901	1.00
124_S	127_Y	0.900	1.00
261_P	315_K	0.899	1.00
11_V	364_Y	0.899	1.00
301_E	491_P	0.899	1.00
10_V	45_A	0.897	1.00
142_S	145_G	0.897	1.00
16_P	50_I	0.895	1.00
81_F	84_L	0.894	1.00
22_S	31_R	0.894	1.00
45_A	93_L	0.890	1.00
79_D	83_E	0.888	1.00
242_D	246_S	0.888	1.00
355_V	511_F	0.883	1.00
148_V	160_L	0.880	1.00
185_M	244_V	0.880	1.00
499_E	502_K	0.878	1.00
83_E	86_D	0.877	1.00
513_K	550_Y	0.874	1.00
47_V	251_M	0.873	1.00
189_L	244_V	0.873	1.00
198_I	275_L	0.872	1.00
118_K	123_R	0.872	1.00
181_V	184_M	0.872	1.00
178_R	182_Y	0.871	1.00
455_Q	466_K	0.870	1.00
303_S	491_P	0.868	1.00
427_S	453_E	0.866	1.00
151_Y	155_T	0.860	1.00
24_G	436_G	0.860	1.00
123_R	157_E	0.860	1.00
485_L	488_P	0.859	1.00
357_Y	363_P	0.858	1.00
124_S	171_N	0.856	1.00
463_N	467_K	0.856	1.00
129_R	210_L	0.854	1.00
48_I	84_L	0.854	1.00
333_R	336_S	0.850	1.00
205_S	236_Y	0.848	1.00
478_L	481_G	0.847	1.00
536_Y	551_E	0.845	1.00
119_N	122_Y	0.840	1.00
59_V	106_V	0.837	1.00
547_F	551_E	0.836	1.00
207_K	210_L	0.834	1.00
450_N	453_E	0.834	1.00
244_V	252_S	0.826	1.00
207_K	211_P	0.825	1.00
186_K	246_S	0.823	1.00
486_L	497_M	0.821	1.00
85_L	193_V	0.820	1.00
13_Q	16_P	0.818	1.00
38_D	42_E	0.817	1.00
303_S	306_K	0.815	1.00
353_A	461_V	0.814	1.00
5_W	9_A	0.810	0.99
521_P	524_C	0.810	0.99
72_M	75_Y	0.810	0.99
451_V	455_Q	0.810	0.99
515_Q	548_R	0.809	0.99
17_R	58_N	0.808	0.99
122_Y	176_E	0.806	0.99
34_I	80_D	0.805	0.99
86_D	89_H	0.803	0.99
357_Y	365_I	0.802	0.99
464_Y	552_S	0.802	0.99
21_D	25_D	0.802	0.99
302_L	306_K	0.801	0.99
508_V	545_M	0.800	0.99
117_D	122_Y	0.800	0.99
332_P	337_R	0.799	0.99
39_Y	451_V	0.799	0.99
340_D	513_K	0.799	0.99
190_D	248_Y	0.797	0.99
47_V	96_V	0.796	0.99
16_P	30_L	0.792	0.99
531_L	538_N	0.791	0.99
439_W	444_P	0.791	0.99
39_Y	462_L	0.789	0.99
495_V	506_L	0.788	0.99
282_Q	311_K	0.787	0.99
483_F	494_F	0.783	0.99
30_L	84_L	0.783	0.99
118_K	155_T	0.782	0.99
336_S	339_G	0.780	0.99
88_V	91_R	0.778	0.99
471_L	475_Y	0.778	0.99
309_L	313_Q	0.776	0.99
164_A	167_Q	0.776	0.99
117_D	121_K	0.774	0.99
40_I	93_L	0.774	0.99
416_R	420_R	0.773	0.99
34_I	91_R	0.772	0.99
347_A	536_Y	0.771	0.99
476_A	480_K	0.768	0.99
333_R	337_R	0.767	0.99
22_S	25_D	0.767	0.99
500_N	503_Q	0.763	0.99
332_P	338_F	0.763	0.99
534_S	551_E	0.763	0.99
309_L	312_W	0.760	0.99
236_Y	240_I	0.759	0.99
257_G	331_Q	0.757	0.99
424_Q	442_V	0.755	0.99
182_Y	240_I	0.754	0.99
298_K	304_D	0.753	0.99
131_G	135_G	0.751	0.99
347_A	350_K	0.751	0.99
434_T	438_P	0.750	0.99
11_V	96_V	0.749	0.99
454_A	457_D	0.747	0.99
234_H	238_K	0.746	0.99
445_N	449_I	0.745	0.99
309_L	359_M	0.741	0.99
298_K	301_E	0.740	0.99
114_A	120_S	0.736	0.99
247_H	250_V	0.736	0.99
121_K	125_Y	0.733	0.99
305_L	309_L	0.733	0.99
20_Q	32_G	0.732	0.99
493_L	518_F	0.731	0.99
279_F	364_Y	0.731	0.99
317_E	360_K	0.730	0.99
110_W	170_L	0.730	0.99
266_K	269_G	0.729	0.99
89_H	94_K	0.729	0.99
531_L	555_Y	0.728	0.99
326_W	334_I	0.727	0.99
356_I	363_P	0.727	0.99
427_S	430_N	0.727	0.99
50_I	84_L	0.724	0.99
8_D	476_A	0.724	0.99
508_V	547_F	0.724	0.99
101_L	184_M	0.723	0.99
58_N	75_Y	0.723	0.99
203_L	228_P	0.722	0.99
235_D	238_K	0.721	0.99
497_M	500_N	0.721	0.99
197_R	330_D	0.719	0.99
282_Q	285_E	0.719	0.99
21_D	27_I	0.718	0.99
207_K	230_G	0.718	0.99
326_W	356_I	0.717	0.99
445_N	448_A	0.716	0.99
421_T	424_Q	0.716	0.99
326_W	355_V	0.713	0.99
245_F	276_N	0.712	0.99
199_D	330_D	0.711	0.99
99_F	198_I	0.709	0.99
202_H	256_V	0.707	0.99
459_D	463_N	0.707	0.99
376_A	379_T	0.706	0.99
345_R	348_S	0.706	0.99
426_N	430_N	0.706	0.99
371_I	424_Q	0.702	0.99
431_A	442_V	0.702	0.99
162_M	227_Q	0.702	0.99
9_A	94_K	0.700	0.99
50_I	81_F	0.700	0.99
534_S	537_N	0.700	0.99
239_E	242_D	0.699	0.99
374_T	449_I	0.699	0.99
265_L	268_T	0.699	0.99
146_C	150_Q	0.696	0.98
269_G	273_H	0.694	0.98
163_N	167_Q	0.694	0.98
204_I	233_I	0.694	0.98
37_L	93_L	0.693	0.98
115_E	154_H	0.693	0.98
281_F	284_M	0.691	0.98
354_A	554_V	0.690	0.98
186_K	247_H	0.689	0.98
179_Q	186_K	0.686	0.98
251_M	277_M	0.686	0.98
114_A	123_R	0.685	0.98
22_S	35_S	0.679	0.98
127_Y	130_P	0.679	0.98
146_C	149_W	0.678	0.98
28_G	32_G	0.676	0.98
424_Q	431_A	0.675	0.98
285_E	288_Q	0.671	0.98
110_W	180_A	0.671	0.98
117_D	123_R	0.671	0.98
170_L	177_V	0.671	0.98
476_A	503_Q	0.670	0.98
10_V	357_Y	0.667	0.98
185_M	198_I	0.667	0.98
277_M	362_T	0.666	0.98
308_V	312_W	0.665	0.98
417_D	422_P	0.664	0.98
239_E	243_E	0.664	0.98
138_T	211_P	0.663	0.98
334_I	352_L	0.661	0.98
534_S	538_N	0.661	0.98
173_E	205_S	0.660	0.98
137_P	140_W	0.659	0.98
348_S	550_Y	0.658	0.98
208_E	211_P	0.658	0.98
189_L	247_H	0.658	0.98
515_Q	549_P	0.657	0.98
39_Y	42_E	0.656	0.98
354_A	358_F	0.655	0.98
371_I	454_A	0.654	0.98
530_S	534_S	0.654	0.98
453_E	456_G	0.652	0.98
189_L	248_Y	0.651	0.98
434_T	437_T	0.647	0.98
127_Y	173_E	0.647	0.98
45_A	48_I	0.646	0.98
22_S	33_I	0.646	0.98
289_Q	296_D	0.646	0.98
277_M	281_F	0.644	0.97
427_S	450_N	0.644	0.97
21_D	29_D	0.643	0.97
179_Q	239_E	0.643	0.97
199_D	329_H	0.642	0.97
417_D	420_R	0.641	0.97
529_A	555_Y	0.641	0.97
415_S	420_R	0.641	0.97
120_S	155_T	0.640	0.97
458_P	463_N	0.640	0.97
471_L	532_L	0.640	0.97
354_A	509_N	0.640	0.97
241_T	276_N	0.639	0.97
138_T	209_Y	0.638	0.97
100_V	103_H	0.638	0.97
446_F	450_N	0.638	0.97
151_Y	154_H	0.636	0.97
138_T	142_S	0.635	0.97
95_L	194_D	0.635	0.97
346_K	459_D	0.633	0.97
279_F	284_M	0.633	0.97
102_N	169_D	0.633	0.97
532_L	535_N	0.632	0.97
483_F	496_Y	0.631	0.97
202_H	257_G	0.630	0.97
493_L	547_F	0.630	0.97
136_P	140_W	0.629	0.97
345_R	454_A	0.629	0.97
65_V	100_V	0.628	0.97
529_A	532_L	0.628	0.97
307_S	310_T	0.627	0.97
164_A	169_D	0.624	0.97
237_L	244_V	0.622	0.97
63_Y	199_D	0.622	0.97
369_E	465_Y	0.620	0.97
430_N	437_T	0.620	0.97
304_D	308_V	0.619	0.97
426_N	450_N	0.619	0.97
50_I	88_V	0.619	0.97
486_L	495_V	0.618	0.97
268_T	320_G	0.618	0.97
230_G	233_I	0.617	0.97
142_S	147_P	0.617	0.97
22_S	29_D	0.617	0.97
357_Y	468_L	0.615	0.97
200_Q	204_I	0.615	0.97
513_K	549_P	0.614	0.97
143_N	228_P	0.612	0.97
283_H	305_L	0.612	0.97
207_K	232_R	0.611	0.97
428_G	452_E	0.611	0.97
415_S	418_H	0.611	0.97
141_L	145_G	0.610	0.97
507_S	554_V	0.609	0.96
231_E	235_D	0.608	0.96
106_V	110_W	0.608	0.96
311_K	315_K	0.608	0.96
475_Y	478_L	0.606	0.96
240_I	244_V	0.606	0.96
199_D	255_E	0.605	0.96
284_M	287_D	0.605	0.96
162_M	203_L	0.605	0.96
144_Y	147_P	0.605	0.96
448_A	453_E	0.604	0.96
46_D	93_L	0.604	0.96
535_N	538_N	0.603	0.96
286_L	308_V	0.603	0.96
120_S	124_S	0.603	0.96
261_P	265_L	0.603	0.96
119_N	124_S	0.602	0.96
271_D	274_E	0.601	0.96
182_Y	186_K	0.600	0.96
453_E	457_D	0.600	0.96
138_T	148_V	0.600	0.96
177_V	180_A	0.598	0.96
278_I	281_F	0.598	0.96
123_R	128_W	0.598	0.96
89_H	95_L	0.596	0.96
439_W	442_V	0.595	0.96
529_A	533_L	0.595	0.96
118_K	121_K	0.592	0.96
183_D	190_D	0.590	0.96
333_R	338_F	0.590	0.96
317_E	482_S	0.589	0.96
23_N	29_D	0.589	0.96
482_S	497_M	0.587	0.96
176_E	180_A	0.587	0.96
284_M	288_Q	0.586	0.96
483_F	486_L	0.585	0.96
431_A	446_F	0.583	0.96
99_F	184_M	0.583	0.96
530_S	533_L	0.582	0.95
332_P	335_V	0.582	0.95
186_K	244_V	0.580	0.95
15_Y	51_C	0.580	0.95
530_S	538_N	0.580	0.95
346_K	461_V	0.580	0.95
23_N	31_R	0.579	0.95
308_V	311_K	0.579	0.95
260_T	263_E	0.578	0.95
144_Y	149_W	0.577	0.95
351_M	550_Y	0.575	0.95
314_K	484_D	0.575	0.95
367_Q	423_M	0.574	0.95
66_T	107_E	0.574	0.95
242_D	245_F	0.574	0.95
63_Y	330_D	0.571	0.95
22_S	84_L	0.571	0.95
118_K	122_Y	0.570	0.95
540_D	543_D	0.570	0.95
198_I	245_F	0.569	0.95
476_A	500_N	0.568	0.95
241_T	252_S	0.568	0.95
85_L	97_M	0.566	0.95
454_A	460_S	0.566	0.95
422_P	425_W	0.565	0.95
171_N	174_N	0.565	0.95
138_T	210_L	0.565	0.95
417_D	421_T	0.565	0.95
111_F	114_A	0.565	0.95
108_H	114_A	0.564	0.95
142_S	148_V	0.564	0.95
265_L	269_G	0.563	0.95
229_N	267_Y	0.563	0.95
424_Q	427_S	0.563	0.95
429_K	434_T	0.563	0.95
529_A	534_S	0.561	0.94
125_Y	128_W	0.561	0.94
488_P	495_V	0.560	0.94
256_V	259_V	0.560	0.94
155_T	158_Y	0.560	0.94
312_W	316_L	0.559	0.94
494_F	509_N	0.559	0.94
178_R	205_S	0.558	0.94
485_L	494_F	0.557	0.94
237_L	241_T	0.556	0.94
253_V	279_F	0.556	0.94
266_K	270_T	0.556	0.94
113_E	119_N	0.555	0.94
548_R	553_R	0.552	0.94
296_D	299_P	0.551	0.94
414_K	418_H	0.551	0.94
486_L	489_D	0.550	0.94
58_N	61_Y	0.550	0.94
63_Y	197_R	0.548	0.94
103_H	199_D	0.548	0.94
427_S	447_T	0.548	0.94
476_A	479_M	0.547	0.94
245_F	248_Y	0.547	0.94
122_Y	180_A	0.547	0.94
39_Y	45_A	0.546	0.94
416_R	419_A	0.545	0.94
55_P	75_Y	0.545	0.94
99_F	196_L	0.545	0.94
278_I	282_Q	0.545	0.94
481_G	500_N	0.544	0.94
45_A	365_I	0.544	0.94
47_V	93_L	0.543	0.93
254_G	275_L	0.543	0.93
234_H	266_K	0.542	0.93
529_A	538_N	0.542	0.93
152_E	157_E	0.542	0.93
335_V	338_F	0.542	0.93
103_H	329_H	0.541	0.93
354_A	507_S	0.541	0.93
334_I	337_R	0.540	0.93
378_F	447_T	0.540	0.93
9_A	96_V	0.540	0.93
39_Y	455_Q	0.539	0.93
197_R	329_H	0.539	0.93
313_Q	360_K	0.537	0.93
422_P	426_N	0.536	0.93
84_L	88_V	0.534	0.93
16_P	75_Y	0.534	0.93
81_F	88_V	0.533	0.93
143_N	203_L	0.533	0.93
111_F	168_A	0.531	0.93
519_Q	522_K	0.531	0.93
262_E	265_L	0.531	0.93
240_I	243_E	0.529	0.93
427_S	431_A	0.529	0.93
350_K	460_S	0.529	0.93
11_V	362_T	0.528	0.93
79_D	191_K	0.527	0.92
545_M	553_R	0.527	0.92
103_H	197_R	0.526	0.92
30_L	33_I	0.526	0.92
487_L	490_D	0.526	0.92
98_D	197_R	0.525	0.92
233_I	236_Y	0.525	0.92
471_L	554_V	0.523	0.92
287_D	414_K	0.523	0.92
42_E	470_S	0.522	0.92
143_N	148_V	0.522	0.92
325_F	328_N	0.522	0.92
349_A	353_A	0.521	0.92
233_I	267_Y	0.521	0.92
531_L	537_N	0.520	0.92
419_A	424_Q	0.519	0.92
148_V	151_Y	0.519	0.92
353_A	365_I	0.519	0.92
271_D	276_N	0.518	0.92
357_Y	369_E	0.518	0.92
111_F	126_Y	0.518	0.92
177_V	184_M	0.516	0.92
353_A	468_L	0.516	0.92
185_M	196_L	0.516	0.92
310_T	313_Q	0.515	0.92
267_Y	271_D	0.515	0.92
109_P	122_Y	0.514	0.92
139_D	210_L	0.514	0.92
34_I	88_V	0.514	0.92
202_H	259_V	0.514	0.92
302_L	305_L	0.514	0.92
158_Y	161_H	0.513	0.91
99_F	181_V	0.512	0.91
120_S	128_W	0.511	0.91
284_M	325_F	0.510	0.91
183_D	186_K	0.510	0.91
336_S	375_N	0.510	0.91
429_K	435_D	0.510	0.91
204_I	237_L	0.510	0.91
14_I	19_F	0.509	0.91
253_V	257_G	0.509	0.91
23_N	26_G	0.509	0.91
542_D	545_M	0.509	0.91
6_W	9_A	0.509	0.91
147_P	151_Y	0.509	0.91
141_L	144_Y	0.507	0.91
85_L	89_H	0.506	0.91
177_V	181_V	0.506	0.91
324_L	361_G	0.505	0.91
115_E	155_T	0.503	0.91
203_L	257_G	0.503	0.91
426_N	446_F	0.503	0.91
418_H	421_T	0.502	0.91
323_T	364_Y	0.502	0.91
416_R	422_P	0.501	0.90
299_P	305_L	0.501	0.90
20_Q	435_D	0.501	0.90
37_L	84_L	0.501	0.90
172_W	204_I	0.500	0.90
137_P	142_S	0.500	0.90

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1uokA	1	0.9929	100	0.141	Contact Map
2ze0A	2	0.9412	100	0.142	Contact Map
4mb1A	1	0.9857	100	0.153	Contact Map
4hphA	1	0.9875	100	0.167	Contact Map
2zicA	1	0.9465	100	0.167	Contact Map
4aieA	1	0.9519	100	0.168	Contact Map
3aj7A	1	0.9893	100	0.169	Contact Map
1zjaA	1	0.984	100	0.176	Contact Map
3wy2A	1	0.9234	100	0.178	Contact Map
3zo9A	4	0.8948	100	0.205	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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