YKOD - BACSU - GREMLIN Contacts

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YKOD - Putative HMP/thiamine import ATP-binding protein YkoD

UniProt:	O34362	Sequences: MQAFDELLTVEQLSFSYEEDEKPVFQDISFELQKGECVLLLGPSGCGKSSLALCLNGLYPEACDGIQSGHVFLFQKPVTDAETSETITQHAGVVFQDPDQQFCMLTVEDEIAFGLENLQIPKEEMTEKINAVLEKLRITHLKEKMISTLSGGQKQKVALACILAMEPELIILDEPTSLLDPFSAREFVHLMKDLQREKGFSLLVIEHQLDEWAPWIERTIVLDKSGKKALDGLTKNLFQHEAETLKKLGIAIPKVCHLQEKLSMPFTLSKEMLFKEPIPAGHVKKKKAPSGESVLEVSSLSFARGQQAIFKDISFSLREGSLTALVGPNGTGKSTLLSVLASLMKPQSGKILLYDQPLQKYKEKELRKRMGFVFQNPEHQFVTDTVYDELLFGQKANAETEKKAQHLLQRFGLAHLADHHPFAISQGQKRRLSVATMLMHDVKVLLLDEPTFGQDARTAAECMEMIQRIKAEGTAVLMITHDMELVSSYADSVLVLHDTGLAFDGSPAQLFSQETGLVQKAKLTLPLLYEWMAFQEEVRDEATVTSH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	547 (487)
Sequences:	1029 (566)
Seq/√Len:	25.6

ECOLI - YEJF GSIA MODF XYLG
BACSU - YKOD YKPA YFMM YFMR
HALSA - Q9HMC1
SULSO - Q97UG5 Y2030 Y1893

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
398_A	402_K	5.202	1.00
299_S	312_D	4.754	1.00
395_K	401_E	3.886	1.00
391_L	401_E	3.691	1.00
303_A	308_A	3.408	1.00
207_H	210_D	3.402	1.00
121_P	124_E	3.385	1.00
467_Q	471_A	3.269	1.00
418_D	421_P	3.212	1.00
243_E	247_K	3.161	1.00
206_E	209_L	3.146	1.00
106_T	109_D	3.120	1.00
391_L	405_Q	3.063	1.00
300_L	351_I	2.971	1.00
244_T	247_K	2.936	1.00
206_E	210_D	2.899	1.00
311_K	500_G	2.898	1.00
56_N	171_I	2.850	1.00
205_I	208_Q	2.841	1.00
250_I	253_P	2.838	1.00
207_H	211_E	2.763	0.99
230_L	233_L	2.739	0.99
293_S	354_Y	2.728	0.99
238_F	247_K	2.592	0.99
242_A	247_K	2.590	0.99
28_I	222_L	2.579	0.99
208_Q	211_E	2.513	0.99
417_A	421_P	2.512	0.99
69_G	75_Q	2.497	0.99
71_V	75_Q	2.421	0.99
339_V	344_M	2.421	0.99
301_S	308_A	2.399	0.98
32_L	38_V	2.373	0.98
243_E	246_K	2.364	0.98
397_N	401_E	2.307	0.98
205_I	209_L	2.288	0.98
301_S	312_D	2.283	0.98
248_L	253_P	2.278	0.98
249_G	253_P	2.260	0.98
242_A	246_K	2.154	0.97
79_T	82_E	2.110	0.97
59_Y	71_V	2.085	0.96
463_M	466_I	2.075	0.96
238_F	243_E	2.037	0.96
72_F	75_Q	2.012	0.95
512_S	516_G	2.004	0.95
69_G	73_L	2.001	0.95
23_P	26_Q	1.997	0.95
240_H	246_K	1.968	0.95
275_K	279_P	1.955	0.95
36_E	218_R	1.954	0.95
384_D	389_E	1.950	0.95
210_D	214_P	1.917	0.94
206_E	211_E	1.909	0.94
258_L	263_S	1.903	0.94
238_F	242_A	1.896	0.94
204_V	207_H	1.886	0.93
391_L	395_K	1.883	0.93
412_G	418_D	1.877	0.93
238_F	244_T	1.874	0.93
418_D	423_A	1.864	0.93
239_Q	242_A	1.840	0.93
275_K	282_H	1.799	0.92
257_H	261_K	1.777	0.91
417_A	432_L	1.775	0.91
204_V	208_Q	1.729	0.90
237_L	253_P	1.726	0.90
248_L	251_A	1.696	0.89
258_L	265_P	1.671	0.88
66_I	73_L	1.663	0.88
417_A	420_H	1.653	0.88
205_I	210_D	1.652	0.88
248_L	252_I	1.650	0.88
136_L	163_L	1.642	0.88
203_L	208_Q	1.639	0.87
272_M	275_K	1.635	0.87
279_P	282_H	1.625	0.87
269_S	275_K	1.618	0.87
258_L	282_H	1.598	0.86
353_L	446_L	1.595	0.86
245_L	250_I	1.586	0.86
202_L	205_I	1.577	0.85
39_L	219_T	1.573	0.85
258_L	269_S	1.549	0.84
301_S	348_S	1.546	0.84
192_K	196_R	1.534	0.84
269_S	272_M	1.530	0.83
265_P	268_L	1.515	0.83
258_L	264_M	1.512	0.83
130_N	142_K	1.508	0.83
268_L	275_K	1.507	0.83
270_K	275_K	1.505	0.82
263_S	269_S	1.505	0.82
318_R	321_S	1.504	0.82
257_H	260_E	1.499	0.82
258_L	261_K	1.497	0.82
78_V	83_T	1.491	0.82
261_K	264_M	1.483	0.81
258_L	279_P	1.481	0.81
263_S	267_T	1.475	0.81
271_E	275_K	1.472	0.81
257_H	269_S	1.469	0.81
239_Q	247_K	1.466	0.81
245_L	253_P	1.461	0.80
269_S	279_P	1.453	0.80
268_L	271_E	1.447	0.80
50_S	64_D	1.443	0.80
51_L	55_L	1.441	0.80
514_E	517_L	1.440	0.80
238_F	246_K	1.439	0.79
233_L	236_N	1.439	0.79
99_D	103_C	1.438	0.79
237_L	250_I	1.438	0.79
297_V	302_F	1.426	0.79
414_A	418_D	1.409	0.78
268_L	279_P	1.408	0.78
270_K	279_P	1.398	0.77
67_Q	71_V	1.386	0.77
264_M	270_K	1.378	0.76
412_G	417_A	1.372	0.76
258_L	270_K	1.370	0.76
258_L	262_L	1.369	0.76
263_S	279_P	1.369	0.76
108_E	142_K	1.360	0.75
26_Q	227_K	1.354	0.75
272_M	279_P	1.347	0.75
280_A	285_K	1.344	0.75
276_E	279_P	1.344	0.75
271_E	274_F	1.339	0.74
264_M	268_L	1.337	0.74
263_S	271_E	1.330	0.74
492_S	506_S	1.323	0.73
401_E	405_Q	1.314	0.73
245_L	251_A	1.309	0.73
257_H	279_P	1.301	0.72
261_K	265_P	1.300	0.72
240_H	243_E	1.298	0.72
203_L	207_H	1.294	0.72
107_V	157_V	1.287	0.71
257_H	270_K	1.287	0.71
265_P	269_S	1.287	0.71
262_L	266_F	1.281	0.71
265_P	279_P	1.280	0.71
237_L	248_L	1.271	0.70
272_M	276_E	1.270	0.70
202_L	207_H	1.267	0.70
417_A	423_A	1.256	0.69
241_E	250_I	1.254	0.69
274_F	279_P	1.249	0.69
265_P	275_K	1.247	0.69
467_Q	470_K	1.246	0.69
485_L	489_Y	1.244	0.69
263_S	275_K	1.241	0.68
257_H	275_K	1.232	0.68
269_S	274_F	1.229	0.68
464_E	467_Q	1.220	0.67
467_Q	489_Y	1.219	0.67
271_E	279_P	1.218	0.67
396_A	399_E	1.216	0.67
240_H	244_T	1.211	0.66
272_M	282_H	1.202	0.66
263_S	286_K	1.200	0.66
260_E	268_L	1.196	0.65
203_L	206_E	1.193	0.65
263_S	270_K	1.189	0.65
258_L	274_F	1.187	0.65
274_F	282_H	1.185	0.65
514_E	518_V	1.183	0.65
238_F	245_L	1.182	0.65
261_K	267_T	1.178	0.64
266_F	269_S	1.176	0.64
258_L	275_K	1.168	0.64
204_V	209_L	1.162	0.63
413_L	418_D	1.158	0.63
511_F	517_L	1.157	0.63
237_L	249_G	1.146	0.62
264_M	279_P	1.145	0.62
258_L	271_E	1.140	0.62
264_M	274_F	1.140	0.62
263_S	276_E	1.140	0.62
508_A	517_L	1.138	0.62
250_I	255_V	1.134	0.61
265_P	270_K	1.130	0.61
250_I	254_K	1.127	0.61
297_V	304_R	1.126	0.61
38_V	202_L	1.123	0.60
274_F	281_G	1.120	0.60
268_L	282_H	1.118	0.60
260_E	275_K	1.117	0.60
414_A	421_P	1.116	0.60
511_F	514_E	1.116	0.60
237_L	245_L	1.115	0.60
261_K	282_H	1.114	0.60
121_P	125_M	1.109	0.59
259_Q	265_P	1.109	0.59
257_H	264_M	1.104	0.59
203_L	211_E	1.103	0.59
425_S	428_Q	1.103	0.59
260_E	263_S	1.100	0.59
202_L	206_E	1.098	0.59
279_P	285_K	1.096	0.59
262_L	265_P	1.095	0.58
94_V	158_A	1.088	0.58
37_C	195_Q	1.084	0.58
264_M	278_I	1.084	0.58
269_S	278_I	1.082	0.58
66_I	75_Q	1.082	0.58
413_L	417_A	1.080	0.57
100_Q	103_C	1.079	0.57
237_L	255_V	1.077	0.57
259_Q	263_S	1.072	0.57
263_S	268_L	1.072	0.57
65_G	69_G	1.071	0.57
265_P	272_M	1.065	0.56
275_K	284_K	1.055	0.56
270_K	274_F	1.053	0.55
263_S	285_K	1.052	0.55
257_H	267_T	1.050	0.55
275_K	285_K	1.046	0.55
248_L	254_K	1.042	0.55
485_L	488_S	1.034	0.54
327_G	332_G	1.025	0.53
240_H	247_K	1.023	0.53
274_F	277_P	1.023	0.53
263_S	274_F	1.021	0.53
54_C	59_Y	1.021	0.53
274_F	280_A	1.017	0.53
262_L	272_M	1.015	0.53
271_E	276_E	1.013	0.53
270_K	282_H	1.011	0.52
69_G	72_F	1.010	0.52
266_F	270_K	1.009	0.52
258_L	268_L	1.007	0.52
282_H	285_K	1.007	0.52
257_H	268_L	1.006	0.52
205_I	211_E	1.006	0.52
240_H	245_L	1.006	0.52
275_K	278_I	1.006	0.52
322_L	466_I	1.006	0.52
338_S	344_M	1.005	0.52
120_I	128_K	0.998	0.51
261_K	269_S	0.994	0.51
39_L	495_V	0.992	0.51
65_G	75_Q	0.989	0.51
202_L	210_D	0.988	0.51
264_M	269_S	0.987	0.51
241_E	247_K	0.986	0.51
125_M	131_A	0.986	0.51
269_S	285_K	0.985	0.50
239_Q	244_T	0.977	0.50
93_V	99_D	0.974	0.50
269_S	282_H	0.973	0.50
269_S	277_P	0.970	0.49
487_S	511_F	0.969	0.49
508_A	518_V	0.967	0.49
25_F	46_C	0.966	0.49
268_L	278_I	0.963	0.49
67_Q	75_Q	0.960	0.49
200_F	207_H	0.960	0.49
91_A	94_V	0.958	0.49
89_Q	93_V	0.956	0.48
112_A	127_E	0.956	0.48
330_G	335_T	0.953	0.48
242_A	245_L	0.952	0.48
239_Q	243_E	0.950	0.48
261_K	276_E	0.948	0.48
513_Q	517_L	0.947	0.48
265_P	274_F	0.946	0.48
127_E	131_A	0.945	0.48
391_L	397_N	0.945	0.48
261_K	266_F	0.941	0.47
244_T	253_P	0.940	0.47
413_L	419_H	0.937	0.47
264_M	283_V	0.936	0.47
259_Q	269_S	0.934	0.47
202_L	208_Q	0.933	0.47
239_Q	246_K	0.928	0.46
93_V	96_Q	0.928	0.46
275_K	280_A	0.926	0.46
261_K	273_L	0.925	0.46
185_R	209_L	0.924	0.46
407_L	410_R	0.923	0.46
345_K	489_Y	0.919	0.46
261_K	279_P	0.917	0.46
257_H	285_K	0.915	0.45
189_H	396_A	0.914	0.45
203_L	210_D	0.911	0.45
83_T	91_A	0.911	0.45
204_V	210_D	0.909	0.45
51_L	220_I	0.907	0.45
257_H	274_F	0.907	0.45
267_T	272_M	0.907	0.45
264_M	267_T	0.905	0.45
46_C	66_I	0.904	0.45
248_L	255_V	0.904	0.45
263_S	280_A	0.904	0.45
223_D	229_A	0.903	0.44
374_F	381_F	0.903	0.44
414_A	417_A	0.900	0.44
264_M	271_E	0.898	0.44
258_L	285_K	0.898	0.44
264_M	275_K	0.896	0.44
136_L	160_A	0.888	0.43
262_L	280_A	0.887	0.43
260_E	269_S	0.885	0.43
266_F	274_F	0.881	0.43
272_M	285_K	0.880	0.43
234_T	245_L	0.877	0.43
258_L	280_A	0.875	0.42
509_Q	512_S	0.874	0.42
247_K	253_P	0.873	0.42
92_G	162_I	0.873	0.42
338_S	341_A	0.872	0.42
108_E	112_A	0.872	0.42
260_E	265_P	0.871	0.42
260_E	270_K	0.869	0.42
262_L	279_P	0.867	0.42
258_L	267_T	0.865	0.42
295_L	302_F	0.861	0.41
259_Q	262_L	0.860	0.41
406_H	409_Q	0.858	0.41
328_P	497_H	0.858	0.41
265_P	271_E	0.856	0.41
241_E	248_L	0.854	0.41
271_E	278_I	0.854	0.41
195_Q	201_S	0.853	0.41
97_D	252_I	0.852	0.41
418_D	422_F	0.851	0.41
71_V	74_F	0.850	0.41
308_A	311_K	0.850	0.41
507_P	511_F	0.850	0.41
268_L	272_M	0.849	0.41
258_L	272_M	0.847	0.40
88_T	95_F	0.846	0.40
43_P	209_L	0.840	0.40
24_V	500_G	0.840	0.40
264_M	282_H	0.838	0.40
261_K	275_K	0.837	0.40
138_I	410_R	0.836	0.40
257_H	262_L	0.834	0.40
132_V	163_L	0.832	0.39
133_L	139_T	0.831	0.39
363_E	369_R	0.828	0.39
513_Q	518_V	0.827	0.39
309_I	329_N	0.821	0.39
65_G	73_L	0.819	0.39
256_C	260_E	0.818	0.38
28_I	51_L	0.818	0.38
27_D	34_K	0.818	0.38
260_E	264_M	0.816	0.38
259_Q	272_M	0.815	0.38
399_E	403_K	0.814	0.38
257_H	276_E	0.814	0.38
235_K	286_K	0.813	0.38
82_E	86_T	0.813	0.38
266_F	275_K	0.812	0.38
92_G	95_F	0.811	0.38
265_P	276_E	0.810	0.38
88_T	93_V	0.810	0.38
275_K	286_K	0.807	0.38
266_F	272_M	0.805	0.38
43_P	185_R	0.805	0.38
327_G	333_K	0.803	0.37
271_E	282_H	0.803	0.37
266_F	276_E	0.801	0.37
259_Q	275_K	0.799	0.37
49_S	92_G	0.798	0.37
257_H	263_S	0.797	0.37
300_L	370_M	0.797	0.37
393_G	433_S	0.793	0.37
264_M	272_M	0.789	0.36
54_C	307_Q	0.784	0.36
240_H	250_I	0.782	0.36
260_E	278_I	0.782	0.36
271_E	285_K	0.782	0.36
141_L	149_L	0.782	0.36
167_P	170_I	0.781	0.36
65_G	71_V	0.781	0.36
122_K	138_I	0.780	0.36
446_L	478_M	0.780	0.36
241_E	244_T	0.780	0.36
64_D	70_H	0.778	0.36
120_I	124_E	0.776	0.36
138_I	209_L	0.775	0.36
309_I	498_D	0.773	0.35
204_V	211_E	0.771	0.35
257_H	278_I	0.770	0.35
330_G	481_H	0.769	0.35
282_H	286_K	0.768	0.35
172_L	225_S	0.764	0.35
262_L	274_F	0.763	0.35
55_L	171_I	0.762	0.35
278_I	285_K	0.762	0.35
142_K	312_D	0.762	0.35
249_G	254_K	0.761	0.35
263_S	266_F	0.761	0.35
200_F	206_E	0.760	0.34
267_T	274_F	0.760	0.34
83_T	90_H	0.760	0.34
296_E	458_T	0.759	0.34
260_E	272_M	0.758	0.34
314_S	465_M	0.755	0.34
241_E	245_L	0.754	0.34
266_F	283_V	0.754	0.34
264_M	276_E	0.753	0.34
260_E	282_H	0.753	0.34
111_I	160_A	0.752	0.34
245_L	248_L	0.752	0.34
30_F	36_E	0.751	0.34
249_G	255_V	0.751	0.34
125_M	130_N	0.749	0.34
173_D	180_D	0.749	0.34
267_T	270_K	0.749	0.34
144_K	376_N	0.749	0.34
266_F	277_P	0.746	0.34
263_S	284_K	0.746	0.34
323_T	492_S	0.746	0.34
389_E	435_A	0.745	0.34
244_T	250_I	0.744	0.33
94_V	162_I	0.742	0.33
267_T	279_P	0.741	0.33
267_T	278_I	0.740	0.33
261_K	285_K	0.739	0.33
32_L	318_R	0.738	0.33
237_L	251_A	0.738	0.33
307_Q	313_I	0.737	0.33
95_F	171_I	0.736	0.33
333_K	349_G	0.736	0.33
265_P	284_K	0.735	0.33
162_I	170_I	0.735	0.33
260_E	266_F	0.734	0.33
258_L	278_I	0.731	0.33
247_K	250_I	0.731	0.33
482_D	490_A	0.731	0.33
125_M	129_I	0.731	0.33
511_F	518_V	0.729	0.32
64_D	67_Q	0.728	0.32
146_I	181_P	0.728	0.32
339_V	372_F	0.728	0.32
273_L	278_I	0.727	0.32
267_T	271_E	0.727	0.32
121_P	131_A	0.727	0.32
257_H	272_M	0.726	0.32
270_K	276_E	0.726	0.32
273_L	276_E	0.726	0.32
262_L	281_G	0.725	0.32
396_A	400_T	0.724	0.32
271_E	284_K	0.723	0.32
259_Q	264_M	0.723	0.32
23_P	476_V	0.723	0.32
419_H	423_A	0.721	0.32
256_C	266_F	0.720	0.32
243_E	254_K	0.720	0.32
270_K	285_K	0.716	0.32
508_A	511_F	0.715	0.32
37_C	188_V	0.714	0.32
270_K	278_I	0.712	0.31
278_I	286_K	0.710	0.31
312_D	408_L	0.710	0.31
408_L	411_F	0.709	0.31
279_P	284_K	0.709	0.31
200_F	204_V	0.709	0.31
264_M	280_A	0.708	0.31
244_T	254_K	0.707	0.31
67_Q	73_L	0.707	0.31
267_T	277_P	0.706	0.31
202_L	209_L	0.704	0.31
266_F	282_H	0.704	0.31
321_S	492_S	0.703	0.31
219_T	234_T	0.702	0.31
326_V	334_S	0.701	0.31
53_L	61_E	0.701	0.31
365_E	477_L	0.701	0.31
262_L	267_T	0.701	0.31
274_F	284_K	0.699	0.31
409_Q	415_H	0.697	0.30
90_H	93_V	0.695	0.30
351_I	370_M	0.694	0.30
32_L	233_L	0.694	0.30
276_E	282_H	0.693	0.30
279_P	283_V	0.692	0.30
377_P	380_Q	0.691	0.30
212_W	458_T	0.690	0.30
103_C	440_H	0.689	0.30
143_E	154_K	0.686	0.30
262_L	283_V	0.683	0.30
414_A	419_H	0.682	0.30
296_E	465_M	0.682	0.30
275_K	283_V	0.682	0.30
69_G	164_A	0.681	0.29
273_L	281_G	0.681	0.29
245_L	254_K	0.679	0.29
307_Q	488_S	0.678	0.29
118_L	439_M	0.677	0.29
46_C	407_L	0.676	0.29
264_M	285_K	0.675	0.29
91_A	185_R	0.675	0.29
412_G	421_P	0.673	0.29
49_S	67_Q	0.672	0.29
267_T	282_H	0.671	0.29
259_Q	273_L	0.671	0.29
268_L	274_F	0.669	0.29
168_E	291_G	0.668	0.29
188_V	459_A	0.668	0.29
213_A	219_T	0.667	0.29
276_E	283_V	0.666	0.29
235_K	276_E	0.666	0.29
327_G	330_G	0.665	0.28
262_L	268_L	0.665	0.28
267_T	273_L	0.664	0.28
402_K	405_Q	0.664	0.28
344_M	443_K	0.661	0.28
175_P	190_L	0.660	0.28
256_C	259_Q	0.660	0.28
27_D	395_K	0.660	0.28
483_M	490_A	0.660	0.28
256_C	262_L	0.659	0.28
494_L	504_D	0.658	0.28
37_C	218_R	0.658	0.28
278_I	398_A	0.657	0.28
508_A	514_E	0.656	0.28
182_F	195_Q	0.656	0.28
327_G	448_D	0.653	0.28
262_L	271_E	0.652	0.28
259_Q	278_I	0.652	0.28
261_K	274_F	0.650	0.28
264_M	281_G	0.649	0.28
258_L	273_L	0.649	0.28
281_G	284_K	0.649	0.28
274_F	285_K	0.648	0.27
260_E	279_P	0.645	0.27
241_E	249_G	0.644	0.27
327_G	349_G	0.643	0.27
268_L	280_A	0.641	0.27
66_I	69_G	0.640	0.27
266_F	278_I	0.639	0.27
257_H	265_P	0.638	0.27
162_I	431_R	0.636	0.27
256_C	265_P	0.635	0.27
133_L	142_K	0.635	0.27
241_E	251_A	0.633	0.27
251_A	255_V	0.633	0.27
240_H	248_L	0.632	0.27
369_R	443_K	0.630	0.26
262_L	275_K	0.629	0.26
419_H	422_F	0.629	0.26
269_S	273_L	0.627	0.26
445_L	477_L	0.626	0.26
274_F	283_V	0.625	0.26
270_K	273_L	0.625	0.26
87_I	447_L	0.624	0.26
57_G	80_D	0.623	0.26
181_P	188_V	0.623	0.26
259_Q	268_L	0.622	0.26
258_L	276_E	0.622	0.26
439_M	488_S	0.622	0.26
263_S	272_M	0.622	0.26
261_K	272_M	0.621	0.26
513_Q	516_G	0.618	0.26
283_V	286_K	0.617	0.26
268_L	273_L	0.617	0.26
271_E	280_A	0.616	0.26
199_G	291_G	0.616	0.26
41_L	385_T	0.613	0.25
159_L	197_E	0.613	0.25
303_A	306_Q	0.610	0.25
191_M	201_S	0.609	0.25
97_D	193_D	0.608	0.25
297_V	315_F	0.607	0.25
186_E	497_H	0.607	0.25
267_T	398_A	0.607	0.25
273_L	279_P	0.604	0.25
265_P	282_H	0.603	0.25
332_G	448_D	0.601	0.25
487_S	507_P	0.599	0.25
115_L	164_A	0.598	0.25
145_M	154_K	0.597	0.25
169_L	464_E	0.597	0.25
213_A	426_Q	0.596	0.25
46_C	143_E	0.596	0.25
512_S	515_T	0.595	0.24
374_F	461_E	0.594	0.24
137_R	373_V	0.594	0.24
129_I	509_Q	0.594	0.24
252_I	255_V	0.593	0.24
261_K	271_E	0.593	0.24
367_R	475_A	0.593	0.24
263_S	282_H	0.591	0.24
269_S	280_A	0.590	0.24
277_P	285_K	0.590	0.24
180_D	448_D	0.589	0.24
95_F	252_I	0.589	0.24
259_Q	276_E	0.588	0.24
332_G	349_G	0.587	0.24
256_C	277_P	0.586	0.24
279_P	286_K	0.585	0.24
68_S	294_V	0.585	0.24
152_G	327_G	0.582	0.24
265_P	285_K	0.582	0.24
365_E	418_D	0.581	0.24
136_L	456_A	0.580	0.24
120_I	290_S	0.580	0.24
313_I	488_S	0.580	0.24
150_S	180_D	0.579	0.24
229_A	252_I	0.579	0.24
59_Y	465_M	0.578	0.24
265_P	278_I	0.578	0.24
115_L	169_L	0.577	0.24
249_G	252_I	0.576	0.23
276_E	285_K	0.576	0.23
327_G	335_T	0.576	0.23
24_V	222_L	0.576	0.23
265_P	273_L	0.575	0.23
268_L	285_K	0.574	0.23
197_E	461_E	0.574	0.23
20_D	26_Q	0.573	0.23
270_K	284_K	0.573	0.23
69_G	74_F	0.573	0.23
51_L	472_E	0.573	0.23
328_P	459_A	0.572	0.23
298_S	515_T	0.572	0.23
66_I	71_V	0.571	0.23
231_D	386_V	0.569	0.23
79_T	94_V	0.568	0.23
266_F	279_P	0.567	0.23
305_G	346_P	0.567	0.23
265_P	283_V	0.567	0.23
203_L	209_L	0.565	0.23
68_S	236_N	0.564	0.23
260_E	274_F	0.564	0.23
244_T	251_A	0.562	0.23
183_S	459_A	0.561	0.23
297_V	477_L	0.561	0.23
436_T	459_A	0.559	0.23
126_T	131_A	0.558	0.23
446_L	492_S	0.558	0.23
43_P	138_I	0.558	0.23
30_F	38_V	0.558	0.23
417_A	422_F	0.557	0.22
55_L	476_V	0.557	0.22
260_E	286_K	0.554	0.22
189_H	356_Q	0.553	0.22
267_T	276_E	0.552	0.22
91_A	135_K	0.551	0.22
83_T	93_V	0.550	0.22
263_S	281_G	0.550	0.22
25_F	50_S	0.549	0.22
288_A	406_H	0.547	0.22
152_G	330_G	0.547	0.22
88_T	91_A	0.547	0.22
94_V	104_M	0.547	0.22
251_A	460_A	0.547	0.22
247_K	251_A	0.547	0.22
263_S	278_I	0.546	0.22
188_V	458_T	0.544	0.22
323_T	502_A	0.543	0.22
45_G	48_K	0.543	0.22
243_E	253_P	0.542	0.22
27_D	265_P	0.542	0.22
23_P	66_I	0.541	0.22
422_F	432_L	0.541	0.22
458_T	465_M	0.540	0.22
245_L	249_G	0.540	0.22
132_V	198_K	0.540	0.22
272_M	281_G	0.540	0.22
101_Q	110_E	0.539	0.22
261_K	268_L	0.539	0.22
177_S	426_Q	0.539	0.22
262_L	269_S	0.538	0.22
57_G	84_S	0.537	0.21
140_H	153_Q	0.537	0.21
140_H	329_N	0.536	0.21
266_F	273_L	0.535	0.21
116_E	342_S	0.535	0.21
296_E	342_S	0.535	0.21
295_L	299_S	0.534	0.21
335_T	481_H	0.534	0.21
262_L	285_K	0.534	0.21
269_S	276_E	0.533	0.21
267_T	396_A	0.533	0.21
238_F	250_I	0.532	0.21
132_V	205_I	0.531	0.21
230_L	426_Q	0.531	0.21
26_Q	67_Q	0.529	0.21
51_L	200_F	0.529	0.21
281_G	285_K	0.527	0.21
152_G	332_G	0.526	0.21
278_I	281_G	0.525	0.21
230_L	236_N	0.524	0.21
84_S	431_R	0.522	0.21
121_P	409_Q	0.522	0.21
266_F	285_K	0.521	0.21
22_K	314_S	0.519	0.21
138_I	415_H	0.519	0.21
367_R	370_M	0.519	0.21
262_L	278_I	0.518	0.21
294_V	353_L	0.515	0.20
271_E	283_V	0.515	0.20
267_T	275_K	0.515	0.20
332_G	335_T	0.514	0.20
183_S	471_A	0.514	0.20
261_K	278_I	0.513	0.20
202_L	211_E	0.512	0.20
108_E	130_N	0.512	0.20
239_Q	245_L	0.512	0.20
265_P	286_K	0.510	0.20
260_E	285_K	0.510	0.20
37_C	56_N	0.510	0.20
267_T	285_K	0.510	0.20
259_Q	285_K	0.509	0.20
273_L	285_K	0.508	0.20
277_P	280_A	0.507	0.20
92_G	97_D	0.507	0.20
143_E	146_I	0.507	0.20
27_D	283_V	0.506	0.20
309_I	470_K	0.506	0.20
39_L	378_E	0.505	0.20
46_C	111_I	0.504	0.20
155_Q	366_L	0.504	0.20
416_L	420_H	0.504	0.20
272_M	278_I	0.503	0.20
168_E	181_P	0.502	0.20
259_Q	277_P	0.501	0.20
262_L	273_L	0.501	0.20
260_E	276_E	0.501	0.20
317_L	477_L	0.501	0.20
116_E	198_K	0.501	0.20
365_E	376_N	0.500	0.20
39_L	194_L	0.500	0.20
115_L	346_P	0.500	0.20

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4f4cA	1	0.8921	100	0.465	Contact Map
4q9hA	1	0.925	100	0.468	Contact Map
4finA	2	0.8848	100	0.505	Contact Map
1yqtA	1	0.9013	100	0.523	Contact Map
2iw3A	2	0.8044	100	0.524	Contact Map
3ozxA	1	0.8702	100	0.531	Contact Map
3bk7A	1	0.9031	100	0.533	Contact Map
3ux8A	2	0.8007	100	0.542	Contact Map
3j16B	1	0.9013	100	0.544	Contact Map
2vf7A	2	0.8793	100	0.596	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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