GREMLIN Database
YDJN - Uncharacterized protein YdjN
UniProt: O34353 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 348 (273)
Sequences: 317 (307)
Seq/√Len: 18.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
300_E304_A5.4601.00
275_Q300_E5.0881.00
226_L248_T4.6581.00
237_D292_G4.4651.00
275_Q298_L4.2771.00
243_L288_F4.0481.00
226_L244_F3.9501.00
258_I298_L3.6121.00
262_N309_D3.3981.00
226_L261_L3.3291.00
281_L286_P2.9260.99
244_F261_L2.9200.99
246_S290_K2.9060.99
246_S257_S2.8120.98
236_S289_S2.7260.98
226_L246_S2.7190.98
244_F256_A2.6930.98
244_F248_T2.5050.97
225_S244_F2.4220.96
243_L297_F2.4170.96
232_D281_L2.3670.95
242_I295_I2.3110.95
227_N307_L2.3020.95
275_Q304_A2.2550.94
248_T257_S2.2100.93
232_D245_T2.1800.93
261_L308_K2.1650.92
259_Q271_I2.1270.92
237_D288_F2.0910.91
297_F307_L2.0900.91
274_N300_E2.0800.91
262_N267_K1.9760.88
260_M292_G1.9400.88
235_V239_D1.9050.87
241_R260_M1.8850.86
248_T261_L1.8670.85
226_L259_Q1.8500.85
285_Q299_A1.8160.84
280_L284_A1.7240.80
57_T286_P1.6960.79
248_T302_K1.6820.79
228_Q231_S1.6780.78
262_N285_Q1.6710.78
225_S261_L1.6400.77
229_F285_Q1.6210.76
235_V291_D1.6030.75
302_K306_K1.5730.74
230_I261_L1.5670.73
237_D260_M1.5630.73
288_F292_G1.5340.72
243_L266_K1.4750.69
223_L228_Q1.4470.67
34_A44_D1.4440.67
223_L230_I1.4420.67
36_V50_I1.4310.66
243_L295_I1.4210.66
245_T299_A1.4040.65
263_A306_K1.3850.64
248_T259_Q1.3760.63
239_D291_D1.3700.63
246_S264_D1.3590.62
266_K291_D1.3530.62
236_S288_F1.3460.61
248_T275_Q1.3350.61
225_S308_K1.3250.60
181_F194_K1.3190.60
246_S284_A1.3010.59
212_F216_R1.2820.58
236_S240_K1.2820.58
275_Q302_K1.2780.57
43_G57_T1.2750.57
256_A277_S1.2650.56
238_D289_S1.2360.55
274_N306_K1.2290.54
52_D258_I1.2230.54
166_D170_S1.2150.53
235_V308_K1.2140.53
258_I286_P1.1850.52
262_N298_L1.1850.52
238_D293_K1.1770.51
281_L298_L1.1750.51
298_L308_K1.1640.50
261_L286_P1.1640.50
230_I263_A1.1630.50
266_K306_K1.1550.50
288_F305_K1.1480.49
134_R223_L1.1340.48
284_A301_A1.1170.47
259_Q304_A1.1050.47
242_I262_N1.1020.46
213_A216_R1.0950.46
259_Q268_Y1.0930.46
38_V43_G1.0920.46
233_I244_F1.0890.46
143_F258_I1.0890.46
46_L50_I1.0870.45
259_Q306_K1.0870.45
94_Q97_M1.0720.44
85_V88_Y1.0690.44
221_N299_A1.0590.44
209_T219_K1.0560.43
217_Q221_N1.0500.43
289_S308_K1.0330.42
209_T281_L1.0310.42
238_D288_F1.0300.42
244_F257_S1.0280.42
196_D206_E1.0240.42
285_Q300_E1.0240.42
149_D152_T1.0220.41
45_E49_S1.0220.41
226_L308_K1.0180.41
49_S53_T1.0150.41
257_S269_E1.0120.41
37_S52_D1.0090.41
234_A239_D1.0060.40
243_L310_E0.9980.40
248_T268_Y0.9930.40
243_L260_M0.9910.40
183_L200_E0.9860.39
239_D306_K0.9820.39
248_T284_A0.9750.39
243_L270_S0.9740.39
242_I248_T0.9740.39
240_K289_S0.9670.38
223_L289_S0.9650.38
46_L52_D0.9610.38
298_L309_D0.9600.38
270_S290_K0.9600.38
243_L305_K0.9590.38
45_E55_L0.9520.37
293_K309_D0.9520.37
298_L302_K0.9490.37
217_Q220_F0.9470.37
263_A273_S0.9440.37
239_D292_G0.9420.37
28_K31_E0.9320.36
272_I287_Q0.9280.36
245_T281_L0.9270.36
244_F298_L0.9270.36
235_V285_Q0.9240.36
243_L292_G0.9230.36
300_E303_G0.9230.36
233_I239_D0.9210.35
111_M262_N0.9210.35
230_I287_Q0.9190.35
208_T212_F0.9180.35
233_I236_S0.9080.35
263_A300_E0.9070.35
53_T57_T0.9030.34
233_I243_L0.8960.34
48_V57_T0.8960.34
194_K197_E0.8940.34
235_V311_T0.8870.34
163_N194_K0.8870.34
230_I238_D0.8800.33
47_L51_T0.8770.33
36_V40_T0.8740.33
276_K298_L0.8700.33
76_A116_A0.8670.32
132_Y143_F0.8650.32
244_F271_I0.8630.32
239_D289_S0.8620.32
231_S247_Y0.8600.32
235_V289_S0.8570.32
263_A288_F0.8540.32
40_T44_D0.8520.32
233_I292_G0.8500.31
274_N308_K0.8490.31
300_E310_E0.8490.31
170_S180_S0.8480.31
120_D140_E0.8470.31
305_K312_G0.8470.31
235_V256_A0.8460.31
84_Q109_K0.8430.31
221_N303_G0.8380.31
262_N280_L0.8360.31
256_A268_Y0.8330.31
235_V299_A0.8320.31
209_T212_F0.8300.30
228_Q248_T0.8290.30
243_L272_I0.8280.30
232_D286_P0.8270.30
37_S45_E0.8260.30
225_S259_Q0.8250.30
91_N157_N0.8240.30
209_T256_A0.8220.30
297_F306_K0.8200.30
211_H214_E0.8200.30
44_D52_D0.8190.30
103_D125_S0.8150.30
289_S300_E0.8090.29
170_S243_L0.8050.29
201_K204_D0.8040.29
50_I150_L0.8030.29
101_K109_K0.8010.29
246_S286_P0.8000.29
274_N302_K0.7970.29
212_F220_F0.7950.29
41_E60_Y0.7890.28
138_A144_R0.7880.28
298_L305_K0.7870.28
149_D217_Q0.7840.28
241_R245_T0.7840.28
209_T215_G0.7810.28
230_I244_F0.7780.28
168_T260_M0.7780.28
243_L286_P0.7760.28
232_D256_A0.7740.28
96_E99_L0.7730.27
99_L102_L0.7700.27
52_D55_L0.7670.27
236_S243_L0.7670.27
61_E119_A0.7650.27
33_A56_L0.7590.27
62_N72_T0.7590.27
113_Y153_K0.7560.27
64_K67_H0.7530.27
44_D54_D0.7500.26
285_Q291_D0.7500.26
95_N98_R0.7470.26
236_S277_S0.7420.26
116_A291_D0.7420.26
298_L304_A0.7390.26
226_L230_I0.7380.26
272_I308_K0.7350.26
228_Q305_K0.7350.26
267_K307_L0.7330.26
298_L310_E0.7330.26
290_K297_F0.7310.25
31_E34_A0.7300.25
259_Q284_A0.7300.25
266_K307_L0.7280.25
122_L180_S0.7270.25
94_Q152_T0.7230.25
219_K222_E0.7230.25
242_I309_D0.7210.25
113_Y173_F0.7200.25
258_I261_L0.7200.25
233_I268_Y0.7180.25
199_N207_P0.7180.25
239_D274_N0.7160.25
272_I306_K0.7130.25
193_K197_E0.7110.25
240_K291_D0.7110.25
30_H33_A0.7080.24
34_A37_S0.7080.24
190_E246_S0.7070.24
132_Y190_E0.7070.24
236_S239_D0.7070.24
244_F308_K0.7060.24
77_F167_D0.7060.24
54_D133_F0.7040.24
125_S130_T0.7040.24
297_F305_K0.7040.24
196_D199_N0.7000.24
244_F268_Y0.6990.24
47_L53_T0.6980.24
228_Q284_A0.6970.24
209_T233_I0.6960.24
236_S242_I0.6960.24
235_V243_L0.6940.24
274_N304_A0.6920.24
232_D241_R0.6910.24
263_A297_F0.6900.24
284_A306_K0.6880.23
261_L285_Q0.6840.23
211_H277_S0.6830.23
280_L309_D0.6790.23
267_K273_S0.6780.23
49_S60_Y0.6780.23
235_V306_K0.6770.23
257_S305_K0.6750.23
229_F301_A0.6750.23
184_L272_I0.6740.23
39_N56_L0.6700.23
41_E44_D0.6620.22
194_K202_G0.6600.22
288_F303_G0.6600.22
277_S303_G0.6590.22
244_F309_D0.6560.22
225_S281_L0.6530.22
209_T298_L0.6520.22
138_A141_S0.6510.22
231_S237_D0.6490.22
132_Y204_D0.6480.22
277_S311_T0.6470.22
57_T60_Y0.6470.22
243_L271_I0.6470.22
274_N298_L0.6460.22
266_K274_N0.6450.22
292_G297_F0.6430.22
233_I304_A0.6410.21
225_S265_T0.6400.21
233_I266_K0.6400.21
227_N303_G0.6380.21
258_I262_N0.6360.21
244_F284_A0.6320.21
272_I295_I0.6310.21
225_S268_Y0.6270.21
37_S44_D0.6240.21
38_V281_L0.6230.21
292_G307_L0.6230.21
211_H219_K0.6210.21
246_S273_S0.6190.21
209_T274_N0.6190.21
183_L192_Y0.6180.20
36_V44_D0.6180.20
42_S47_L0.6170.20
192_Y198_A0.6150.20
229_F256_A0.6120.20
66_I73_S0.6110.20
289_S292_G0.6090.20
274_N289_S0.6090.20
115_G155_Y0.6040.20
84_Q188_V0.6040.20
263_A293_K0.6020.20
110_T135_L0.6010.20
214_E221_N0.5970.20
140_E277_S0.5950.20
55_L60_Y0.5930.19
230_I248_T0.5920.19
200_E203_I0.5920.19
105_K108_K0.5900.19
263_A299_A0.5880.19
181_F281_L0.5860.19
236_S303_G0.5860.19
81_Q90_G0.5850.19
124_L137_K0.5850.19
267_K272_I0.5830.19
210_I284_A0.5820.19
256_A297_F0.5810.19
108_K111_M0.5790.19
114_K119_A0.5780.19
212_F280_L0.5730.19
38_V51_T0.5720.19
49_S230_I0.5710.19
272_I302_K0.5700.19
243_L299_A0.5680.19
178_N204_D0.5670.18
41_E284_A0.5650.18
210_I214_E0.5620.18
206_E290_K0.5620.18
190_E193_K0.5610.18
165_Q190_E0.5610.18
29_G32_K0.5610.18
238_D275_Q0.5610.18
209_T305_K0.5600.18
63_D295_I0.5600.18
248_T309_D0.5600.18
157_N167_D0.5600.18
140_E184_L0.5590.18
187_S269_E0.5580.18
117_E175_N0.5570.18
217_Q299_A0.5570.18
40_T101_K0.5560.18
44_D105_K0.5550.18
173_F197_E0.5500.18
121_S257_S0.5480.18
94_Q158_L0.5470.18
77_F90_G0.5440.18
247_Y301_A0.5430.18
247_Y300_E0.5430.18
224_K299_A0.5410.18
245_T302_K0.5400.17
236_S293_K0.5370.17
258_I267_K0.5360.17
40_T49_S0.5350.17
47_L93_E0.5340.17
149_D153_K0.5340.17
153_K156_K0.5330.17
233_I241_R0.5330.17
175_N197_E0.5320.17
179_D294_N0.5320.17
75_P143_F0.5320.17
207_P306_K0.5310.17
158_L182_A0.5300.17
236_S269_E0.5290.17
49_S52_D0.5270.17
40_T45_E0.5260.17
116_A130_T0.5260.17
239_D300_E0.5260.17
110_T218_N0.5260.17
209_T220_F0.5250.17
299_A310_E0.5250.17
271_I293_K0.5240.17
259_Q275_Q0.5210.17
67_H173_F0.5200.17
101_K113_Y0.5180.17
242_I277_S0.5180.17
35_D133_F0.5180.17
230_I285_Q0.5170.17
268_Y304_A0.5170.17
200_E206_E0.5160.17
90_G123_F0.5150.17
41_E51_T0.5150.17
180_S195_T0.5150.17
234_A299_A0.5140.17
53_T148_F0.5130.17
228_Q242_I0.5130.17
242_I288_F0.5110.16
228_Q301_A0.5100.16
230_I311_T0.5090.16
54_D60_Y0.5090.16
258_I290_K0.5050.16
294_N313_R0.5050.16
230_I240_K0.5050.16
241_R307_L0.5040.16
70_K73_S0.5030.16
211_H284_A0.5000.16
226_L284_A0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4u1eI 1 0.3305 99.9 0.627 Contact Map
1vyhC 1 0.4511 99.8 0.656 Contact Map
4ui9I 1 0.3362 99.8 0.66 Contact Map
4j0wA 1 0.342 99.8 0.661 Contact Map
4j87A 1 0.454 99.8 0.663 Contact Map
3f3fA 1 0.342 99.8 0.667 Contact Map
4j73A 1 0.3362 99.8 0.668 Contact Map
3j60g 1 0.5029 99.8 0.67 Contact Map
3zey7 1 0.4713 99.8 0.672 Contact Map
5a1uC 1 0.4483 99.8 0.673 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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