YTMI - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YTMI - Uncharacterized N-acetyltransferase YtmI

UniProt:	O34350	Sequences: MSDDIFRLATVEDASELLKLVNSAFQPIRQLDIDWPSTRADIQMVSENIEHHSAIVLERDGKLISTITIRFPWESETPPSKYPFVWWFATLPEYKGQGAGSKLLTYVEEKVLRDMLKAPALTLGTSARKHPWLADMYRRRGYEVYFEQEKDGDIGVMMHKVLIPERFNPTLLGAPSWA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	178 (144)
Sequences:	3240 (2485)
Seq/√Len:	207.1

ECOLI - YAFP YJGM PHNO YEDL MNAT RIMI YPEA
BACSU - YTMI YESJ YXEL PAIA YWNH YSNE YHFO YRKN YBFA YHDJ YQJY RIMI YUAI YYAR
HALSA - Q9HSL3 Q9HMI8 Q9HMF0 Q9HQD2
SULSO - Y209 Q7LXZ8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
7_R	58_E	4.159	1.00
108_E	142_Y	4.039	1.00
23_S	91_L	2.961	1.00
57_L	99_A	2.826	1.00
64_I	94_Y	2.600	1.00
55_I	106_Y	2.239	1.00
110_K	115_M	2.223	1.00
138_R	144_V	2.199	1.00
104_L	140_R	2.188	1.00
15_S	42_I	2.077	1.00
59_R	97_Q	2.073	1.00
67_I	107_V	2.072	1.00
123_L	137_Y	2.064	1.00
144_V	147_E	2.033	1.00
106_Y	109_E	1.988	1.00
23_S	92_P	1.940	1.00
58_E	61_G	1.887	1.00
85_V	104_L	1.855	1.00
59_R	64_I	1.807	1.00
110_K	116_L	1.799	1.00
7_R	13_D	1.795	1.00
57_L	65_S	1.792	1.00
9_A	17_L	1.781	1.00
101_S	140_R	1.772	1.00
62_K	93_E	1.732	1.00
134_A	138_R	1.729	1.00
56_V	63_L	1.726	1.00
19_K	23_S	1.696	1.00
108_E	121_L	1.650	1.00
47_E	51_H	1.606	1.00
83_P	113_R	1.601	1.00
65_S	90_T	1.503	1.00
101_S	105_T	1.484	1.00
9_A	56_V	1.432	1.00
11_V	50_E	1.418	1.00
134_A	158_M	1.417	1.00
59_R	94_Y	1.399	1.00
67_I	103_L	1.388	1.00
41_D	44_M	1.373	1.00
14_A	49_I	1.354	1.00
67_I	88_F	1.351	1.00
101_S	139_R	1.336	1.00
125_T	133_L	1.334	1.00
85_V	123_L	1.327	1.00
6_F	106_Y	1.326	1.00
71_F	118_A	1.321	1.00
69_I	107_V	1.319	1.00
36_P	39_R	1.317	1.00
109_E	115_M	1.307	1.00
106_Y	110_K	1.294	1.00
9_A	54_A	1.268	1.00
82_Y	120_A	1.242	1.00
27_P	95_K	1.237	1.00
16_E	63_L	1.224	1.00
92_P	95_K	1.210	1.00
10_T	13_D	1.190	1.00
135_D	138_R	1.168	1.00
11_V	46_S	1.159	1.00
94_Y	97_Q	1.127	1.00
21_V	66_T	1.123	1.00
62_K	91_L	1.120	1.00
16_E	19_K	1.118	1.00
125_T	130_H	1.105	1.00
65_S	103_L	1.100	1.00
23_S	93_E	1.098	1.00
130_H	133_L	1.089	1.00
128_R	154_I	1.084	1.00
144_V	158_M	1.075	1.00
42_I	46_S	1.069	1.00
83_P	118_A	1.036	1.00
58_E	63_L	1.033	1.00
134_A	144_V	0.988	1.00
102_K	105_T	0.974	1.00
105_T	140_R	0.972	1.00
90_T	99_A	0.971	1.00
16_E	62_K	0.967	1.00
26_Q	29_R	0.955	0.99
98_G	101_S	0.950	0.99
147_E	154_I	0.949	0.99
109_E	114_D	0.943	0.99
152_G	155_G	0.943	0.99
16_E	91_L	0.941	0.99
71_F	83_P	0.939	0.99
100_G	137_Y	0.929	0.99
144_V	156_V	0.922	0.99
46_S	50_E	0.922	0.99
35_W	39_R	0.921	0.99
19_K	22_N	0.918	0.99
53_S	110_K	0.917	0.99
48_N	87_W	0.916	0.99
67_I	85_V	0.881	0.99
5_I	58_E	0.878	0.99
57_L	64_I	0.868	0.99
24_A	89_A	0.865	0.99
17_L	66_T	0.860	0.99
113_R	121_L	0.860	0.99
85_V	121_L	0.856	0.99
105_T	109_E	0.855	0.99
34_D	37_S	0.855	0.99
121_L	142_Y	0.840	0.99
25_F	28_I	0.825	0.99
43_Q	46_S	0.818	0.98
84_F	133_L	0.817	0.98
70_R	86_W	0.816	0.98
33_I	36_P	0.811	0.98
66_T	89_A	0.802	0.98
86_W	124_G	0.789	0.98
133_L	136_M	0.789	0.98
9_A	13_D	0.783	0.98
26_Q	30_Q	0.781	0.98
31_L	132_W	0.781	0.98
71_F	116_L	0.780	0.98
149_E	154_I	0.769	0.98
20_L	63_L	0.766	0.98
18_L	22_N	0.756	0.97
28_I	130_H	0.750	0.97
17_L	56_V	0.748	0.97
14_A	45_V	0.747	0.97
45_V	48_N	0.747	0.97
64_I	99_A	0.746	0.97
47_E	50_E	0.745	0.97
138_R	158_M	0.745	0.97
35_W	124_G	0.745	0.97
54_A	68_T	0.738	0.97
133_L	137_Y	0.732	0.97
59_R	62_K	0.727	0.97
69_I	83_P	0.724	0.97
48_N	68_T	0.720	0.96
34_D	39_R	0.720	0.96
22_N	26_Q	0.716	0.96
62_K	94_Y	0.716	0.96
84_F	124_G	0.716	0.96
8_L	53_S	0.714	0.96
14_A	18_L	0.713	0.96
25_F	87_W	0.712	0.96
18_L	42_I	0.710	0.96
7_R	56_V	0.706	0.96
132_W	135_D	0.699	0.96
27_P	30_Q	0.696	0.96
95_K	132_W	0.695	0.96
150_K	153_D	0.691	0.96
100_G	136_M	0.688	0.95
13_D	58_E	0.686	0.95
82_Y	122_T	0.685	0.95
6_F	103_L	0.682	0.95
74_E	82_Y	0.660	0.94
28_I	124_G	0.653	0.94
88_F	100_G	0.649	0.94
95_K	136_M	0.648	0.94
125_T	134_A	0.635	0.93
53_S	69_I	0.635	0.93
93_E	97_Q	0.632	0.93
104_L	108_E	0.629	0.93
127_A	133_L	0.627	0.93
16_E	20_L	0.626	0.93
124_G	130_H	0.625	0.93
96_G	136_M	0.622	0.92
15_S	19_K	0.620	0.92
150_K	155_G	0.620	0.92
20_L	89_A	0.619	0.92
20_L	24_A	0.613	0.92
28_I	31_L	0.608	0.91
9_A	49_I	0.606	0.91
66_T	87_W	0.604	0.91
14_A	54_A	0.603	0.91
87_W	130_H	0.602	0.91
155_G	158_M	0.600	0.91
57_L	103_L	0.595	0.91
8_L	52_H	0.593	0.90
36_P	40_A	0.590	0.90
14_A	42_I	0.588	0.90
21_V	89_A	0.585	0.90
20_L	70_R	0.581	0.90
131_P	135_D	0.580	0.89
21_V	87_W	0.577	0.89
96_G	132_W	0.572	0.89
149_E	152_G	0.568	0.89
25_F	124_G	0.565	0.88
125_T	156_V	0.565	0.88
55_I	69_I	0.561	0.88
88_F	140_R	0.559	0.88
57_L	102_K	0.556	0.87
74_E	122_T	0.556	0.87
94_Y	99_A	0.554	0.87
17_L	21_V	0.554	0.87
147_E	156_V	0.550	0.87
91_L	94_Y	0.550	0.87
89_A	133_L	0.550	0.87
69_I	110_K	0.549	0.87
18_L	87_W	0.548	0.87
132_W	139_R	0.544	0.86
6_F	65_S	0.540	0.86
45_V	66_T	0.540	0.86
28_I	155_G	0.538	0.86
87_W	124_G	0.532	0.85
10_T	61_G	0.524	0.84
27_P	31_L	0.523	0.84
66_T	127_A	0.523	0.84
99_A	102_K	0.521	0.84
95_K	100_G	0.519	0.84
8_L	55_I	0.516	0.83
83_P	121_L	0.514	0.83
55_I	110_K	0.513	0.83
120_A	145_Y	0.511	0.83
125_T	132_W	0.511	0.83
40_A	48_N	0.510	0.83
84_F	122_T	0.509	0.82
54_A	66_T	0.509	0.82
11_V	14_A	0.508	0.82
10_T	15_S	0.507	0.82
15_S	62_K	0.507	0.82
31_L	143_E	0.507	0.82
11_V	49_I	0.506	0.82
37_S	40_A	0.505	0.82
107_V	158_M	0.500	0.81
51_H	60_D	0.500	0.81

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2oh1A	1	0.882	99.9	0.385	Contact Map
2fiaA	1	0.8652	99.9	0.422	Contact Map
2j8mA	2	0.8933	99.9	0.43	Contact Map
2pc1A	1	0.882	99.9	0.44	Contact Map
3zj0A	1	0.8708	99.9	0.445	Contact Map
3h4qA	1	0.7753	99.9	0.445	Contact Map
1gheA	1	0.8652	99.9	0.446	Contact Map
3kkwA	1	0.8539	99.9	0.448	Contact Map
3dr6A	2	0.9045	99.9	0.448	Contact Map
4l8aA	1	0.8539	99.9	0.452	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0064 seconds.