GREMLIN Database
YJOA - Uncharacterized protein YjoA
UniProt: O34334 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 154 (140)
Sequences: 668 (566)
Seq/√Len: 47.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
100_Q103_R3.7711.00
76_T80_V3.5511.00
104_E114_K3.3731.00
106_D114_K3.2291.00
74_T77_D2.7181.00
12_L90_V2.6571.00
23_E83_K2.5761.00
80_V84_T2.5351.00
18_T132_K2.3511.00
87_E91_A2.2781.00
97_T100_Q2.2501.00
23_E79_N2.1951.00
19_N23_E2.1091.00
27_K76_T2.0631.00
33_K40_S2.0511.00
79_N83_K2.0170.99
133_G136_F1.9590.99
10_H122_Q1.9420.99
14_H126_E1.8850.99
104_E116_T1.7490.99
19_N83_K1.6890.98
30_Y78_L1.6840.98
116_T119_A1.6480.98
47_H127_H1.6470.98
8_V94_E1.6280.98
30_Y42_E1.6120.97
127_H133_G1.5660.97
132_K139_V1.5560.97
22_A45_V1.5470.97
77_D80_V1.5320.97
55_F124_A1.5020.96
84_T88_K1.4970.96
25_I75_E1.4860.96
6_Q118_R1.4480.95
58_V64_A1.4400.95
32_Y141_E1.4030.94
34_P138_Y1.3810.94
91_A94_E1.3710.94
40_S43_E1.3680.93
107_L120_L1.3470.93
115_V120_L1.3470.93
49_L52_F1.3240.92
36_E143_G1.3170.92
5_N9_S1.2950.91
30_Y45_V1.2390.90
33_K36_E1.2010.88
8_V90_V1.1940.88
39_M123_L1.1790.87
20_E23_E1.1700.87
92_I95_Q1.1650.86
22_A82_A1.1650.86
18_T130_H1.1540.86
32_Y142_M1.1450.85
90_V94_E1.1380.85
29_H142_M1.1230.84
49_L85_Y1.1170.84
19_N79_N1.1090.84
56_A60_K1.0930.83
35_A38_S1.0890.82
25_I41_A1.0850.82
45_V135_L1.0550.80
15_R128_E1.0550.80
26_S75_E1.0390.79
27_K75_E1.0160.78
21_L133_G1.0070.77
127_H136_F1.0070.77
41_A44_L1.0040.77
86_T128_E1.0020.77
44_L77_D0.9890.76
33_K82_A0.9810.75
115_V119_A0.9730.75
33_K141_E0.9710.75
81_L84_T0.9700.74
41_A75_E0.9650.74
31_S91_A0.9550.73
80_V97_T0.9470.73
40_S47_H0.9300.71
72_E77_D0.9280.71
130_H137_V0.9270.71
55_F123_L0.9260.71
41_A135_L0.9240.71
26_S29_H0.9170.70
11_F38_S0.9130.70
22_A49_L0.9120.70
21_L139_V0.9080.69
30_Y75_E0.8920.68
18_T139_V0.8880.68
7_I121_L0.8840.67
15_R86_T0.8770.67
38_S126_E0.8700.66
46_K78_L0.8660.66
22_A30_Y0.8630.65
104_E107_L0.8620.65
137_V141_E0.8580.65
14_H17_V0.8530.65
130_H134_N0.8370.63
35_A141_E0.8350.63
54_L111_F0.8330.63
24_K146_E0.8300.62
5_N81_L0.8280.62
9_S16_N0.8140.61
44_L134_N0.8090.60
9_S119_A0.8050.60
25_I30_Y0.7990.59
49_L81_L0.7910.59
63_N95_Q0.7810.58
51_S54_L0.7800.58
51_S59_I0.7790.58
33_K37_T0.7730.57
126_E129_I0.7710.57
91_A95_Q0.7620.56
31_S42_E0.7620.56
82_A128_E0.7540.55
14_H132_K0.7540.55
10_H126_E0.7520.55
25_I139_V0.7490.55
21_L146_E0.7450.54
48_I135_L0.7300.53
18_T22_A0.7240.52
8_V87_E0.7210.52
75_E79_N0.7200.52
42_E133_G0.7170.51
67_F70_K0.7150.51
50_T105_I0.7080.50
138_Y141_E0.7020.50
77_D81_L0.7000.50
34_P135_L0.6920.49
105_I117_G0.6900.49
8_V91_A0.6880.48
14_H45_V0.6830.48
73_E80_V0.6800.48
96_L100_Q0.6790.48
14_H128_E0.6770.47
86_T125_M0.6760.47
74_T104_E0.6670.46
36_E104_E0.6660.46
38_S135_L0.6650.46
68_Q100_Q0.6640.46
47_H135_L0.6620.46
71_Q121_L0.6600.46
75_E146_E0.6570.45
33_K138_Y0.6560.45
41_A146_E0.6540.45
46_K72_E0.6540.45
58_V107_L0.6520.45
32_Y138_Y0.6500.45
101_L136_F0.6480.44
18_T35_A0.6480.44
70_K91_A0.6410.44
23_E31_S0.6390.44
55_F111_F0.6350.43
22_A25_I0.6350.43
14_H86_T0.6310.43
11_F125_M0.6310.43
45_V49_L0.6270.42
47_H51_S0.6270.42
138_Y142_M0.6210.42
6_Q137_V0.6150.41
60_K112_G0.6120.41
14_H129_I0.6080.41
5_N119_A0.6060.40
24_K139_V0.6040.40
12_L94_E0.6010.40
25_I127_H0.6000.40
21_L132_K0.5980.40
11_F128_E0.5980.40
70_K104_E0.5930.39
53_H56_A0.5930.39
21_L136_F0.5920.39
54_L58_V0.5920.39
5_N65_S0.5900.39
10_H14_H0.5870.39
38_S137_V0.5870.39
50_T54_L0.5860.38
67_F98_E0.5840.38
47_H82_A0.5800.38
79_N99_E0.5790.38
45_V93_L0.5790.38
27_K30_Y0.5730.37
53_H92_I0.5730.37
131_H134_N0.5710.37
65_S80_V0.5680.37
30_Y79_N0.5680.37
96_L115_V0.5670.37
73_E102_D0.5620.36
61_E64_A0.5610.36
16_N106_D0.5600.36
30_Y55_F0.5570.36
57_N98_E0.5560.36
24_K93_L0.5530.35
98_E118_R0.5510.35
38_S146_E0.5430.34
73_E84_T0.5430.34
21_L143_G0.5370.34
132_K136_F0.5360.34
30_Y72_E0.5340.34
17_V132_K0.5290.33
49_L92_I0.5290.33
120_L124_A0.5240.33
24_K148_P0.5230.33
17_V38_S0.5170.32
138_Y148_P0.5150.32
21_L127_H0.5080.31
50_T81_L0.5070.31
50_T71_Q0.5070.31
105_I120_L0.5050.31
67_F111_F0.5040.31
14_H44_L0.5030.31
76_T99_E0.5020.31
7_I11_F0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2p1aA 2 0.9286 99.9 0.481 Contact Map
3dkaA 2 0.961 99.9 0.483 Contact Map
3gorA 2 0.9935 99.9 0.499 Contact Map
2hkvA 2 0.9416 99.9 0.523 Contact Map
2f22A 2 0.9091 99.9 0.539 Contact Map
3di5A 1 0.9545 99.9 0.544 Contact Map
2qe9A 2 0.9935 99.8 0.564 Contact Map
2qnlA 2 0.9026 99.8 0.576 Contact Map
3cexA 2 0.9221 99.8 0.591 Contact Map
1rxqA 3 0.9351 99.8 0.595 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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