YKOW - BACSU - GREMLIN Contacts

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YKOW - Signaling protein YkoW

UniProt:	O34311	Sequences: MEIHVTYNTTLICLSILIACTASYISLELSRKVTINTGLKSKIWLIGGSLIMGFGIWSMHFVGMMAVHMEMPMEYEFMPLMAAIGASVSGSFVSLYFVSRHILTYYRLLTGSVVLGASIASMHYIGMSAISRVMIIYEPILFTVSIIIAIAASFVSLKIFFDLAVKKHSEHLIFYKGVSSIVMGIGISGMHYTGMLAATFHKDMAPPGSHMEVQTFHWSIFVTLIIFCIQTLLLFSSHADRKFIKQSERIKDNEQRFQSLIVHNIDAIFILSLEGDIISSNHAGEEMISKFGFSMHDWRNYTSLKVKRLFEQVKKDKQAMNSDSDLITEKGQFHLNITLIPVEVNQELDSIYVICKDMTKQYKAEKEIHRMAHYDSLTDLPNRRHAISHLTKVLNREHSLHYNTVVFFLDLNRFKVINDALGHNVGDQLLQFAAKRLSSVVPDNGFIARLGGDEFIIILTDANTGTGEADVLARKIIQKFKKPFKIQDHTLVTSVSIGIAISPKDGTDGLELMKKADMAMYAAKERNKSKYRYYSFSIGNKETVKLNQEMVLREAIENDRFVLHYQPQFSVKKQKMTGAEALIRLVTPDGQLRPPGEFIGVAEETGLIIDIGKWIIDEACKQARIWHDKGYDLSVAINISARQFQSKDLIPLIKDTLNKYQLPPQLLEVEVTESMTMDNLNHSKKVLSSLTELGIRISIDDFGTGHSSLSYLKDFPIHRLKIDKSFIDDIQTHPKSEQITGAIIAMGHQLSLQVIAEGVENAAQKQLLFEKGCDHLQGFFFSRPIPPEQFEQFIIEQPSQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	800 (645)
Sequences:	2633 (2173)
Seq/√Len:	85.6

ECOLI - YEGE DOSP GMR YFGF YFEA YLIE YHJK CSRD YLAB YJCC RTN YCGG ADRB
BACSU - YKOW

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
579_A	790_F	5.517	1.00
782_S	785_I	4.915	1.00
617_D	659_K	4.846	1.00
442_P	445_G	4.717	1.00
724_K	728_D	4.404	1.00
370_R	374_Y	4.395	1.00
612_G	643_Q	4.089	1.00
571_V	776_L	4.062	1.00
691_T	718_H	3.968	1.00
544_V	597_E	3.877	1.00
759_V	776_L	3.751	1.00
656_T	660_Y	3.652	1.00
570_S	573_K	3.572	1.00
587_T	591_Q	3.433	1.00
639_I	649_L	3.365	1.00
299_R	303_S	3.287	1.00
407_F	497_I	3.282	1.00
654_K	693_L	3.243	1.00
508_D	511_E	3.061	1.00
441_V	447_I	3.055	1.00
748_H	774_D	3.037	1.00
565_Y	622_Q	3.024	1.00
618_E	621_K	2.983	1.00
613_K	652_L	2.973	1.00
713_K	736_S	2.945	1.00
583_I	611_I	2.938	1.00
266_D	356_K	2.824	1.00
503_P	506_G	2.820	1.00
563_L	614_W	2.740	1.00
562_V	586_V	2.715	1.00
587_T	590_G	2.634	1.00
564_H	786_P	2.634	1.00
551_V	587_T	2.625	1.00
386_A	456_I	2.571	1.00
409_L	495_V	2.478	1.00
389_H	446_F	2.446	1.00
583_I	615_I	2.399	1.00
767_L	771_K	2.331	1.00
588_P	591_Q	2.284	1.00
561_F	583_I	2.261	1.00
385_H	389_H	2.245	1.00
762_A	766_Q	2.235	1.00
385_H	446_F	2.234	1.00
361_Q	365_E	2.211	1.00
269_F	353_V	2.179	1.00
569_F	781_F	2.130	1.00
459_L	472_L	2.125	1.00
623_A	662_L	2.125	1.00
622_Q	626_W	2.119	1.00
687_L	697_I	2.111	1.00
300_N	303_S	2.110	1.00
407_F	473_A	2.072	1.00
583_I	614_W	2.058	1.00
551_V	590_G	2.050	1.00
336_N	356_K	2.015	1.00
267_A	287_M	2.004	1.00
668_E	719_R	2.000	1.00
552_L	561_F	1.984	1.00
627_H	666_L	1.982	1.00
626_W	787_P	1.980	1.00
765_K	780_F	1.969	1.00
323_D	362_Y	1.945	1.00
506_G	515_K	1.944	1.00
622_Q	787_P	1.934	1.00
563_L	583_I	1.933	1.00
568_Q	775_H	1.917	1.00
568_Q	578_G	1.916	1.00
267_A	281_N	1.911	1.00
267_A	355_C	1.907	1.00
649_L	653_I	1.903	1.00
418_N	426_G	1.891	1.00
637_I	667_L	1.873	1.00
499_I	533_Y	1.857	1.00
294_S	329_E	1.851	1.00
473_A	499_I	1.842	1.00
731_Q	763_A	1.842	1.00
410_D	524_K	1.835	1.00
413_R	528_K	1.826	1.00
731_Q	737_E	1.822	1.00
419_D	517_D	1.810	1.00
362_Y	365_E	1.805	1.00
405_V	501_I	1.797	1.00
452_G	521_Y	1.785	1.00
477_I	497_I	1.777	1.00
408_F	520_M	1.774	1.00
432_F	435_K	1.754	1.00
765_K	781_F	1.748	1.00
602_A	611_I	1.730	1.00
517_D	521_Y	1.721	1.00
657_L	662_L	1.718	1.00
412_N	496_S	1.717	1.00
419_D	521_Y	1.708	1.00
562_V	592_L	1.700	1.00
620_C	667_L	1.696	1.00
290_K	329_E	1.694	1.00
454_E	517_D	1.693	1.00
563_L	615_I	1.681	1.00
641_A	674_S	1.681	1.00
548_Q	601_V	1.680	1.00
753_Q	774_D	1.672	1.00
549_E	553_R	1.667	1.00
748_H	754_V	1.661	1.00
272_S	276_D	1.638	1.00
474_R	478_Q	1.637	1.00
545_K	604_E	1.637	1.00
560_R	587_T	1.632	1.00
399_S	442_P	1.631	1.00
411_L	433_A	1.619	1.00
614_W	618_E	1.617	1.00
428_Q	431_Q	1.617	1.00
261_I	279_S	1.612	1.00
225_I	228_C	1.608	1.00
423_H	517_D	1.607	1.00
415_K	521_Y	1.607	1.00
257_F	260_L	1.607	1.00
599_I	608_I	1.606	1.00
761_N	764_Q	1.602	1.00
618_E	622_Q	1.599	1.00
586_V	592_L	1.595	1.00
341_P	350_S	1.585	1.00
699_I	717_I	1.584	1.00
284_G	288_I	1.580	1.00
594_P	600_G	1.560	1.00
417_I	429_L	1.552	1.00
667_L	695_I	1.552	1.00
560_R	588_P	1.548	1.00
413_R	549_E	1.546	1.00
554_E	558_N	1.542	1.00
435_K	438_S	1.536	1.00
698_S	719_R	1.534	1.00
739_I	746_M	1.532	1.00
563_L	619_A	1.530	1.00
644_F	687_L	1.526	1.00
779_F	784_P	1.526	1.00
269_F	277_I	1.519	1.00
423_H	521_Y	1.517	1.00
599_I	672_T	1.513	1.00
624_R	628_D	1.511	1.00
239_A	243_F	1.511	1.00
526_R	532_R	1.503	0.99
653_I	690_L	1.501	0.99
257_F	261_I	1.500	0.99
762_A	780_F	1.466	0.99
737_E	767_L	1.463	0.99
744_I	773_C	1.462	0.99
432_F	436_R	1.458	0.99
616_I	637_I	1.456	0.99
386_A	448_A	1.450	0.99
596_G	724_K	1.446	0.99
568_Q	668_E	1.436	0.99
634_S	696_R	1.435	0.99
603_E	608_I	1.433	0.99
590_G	597_E	1.432	0.99
436_R	483_P	1.430	0.99
554_E	560_R	1.427	0.99
429_L	493_T	1.421	0.99
432_F	484_F	1.419	0.99
568_Q	719_R	1.416	0.99
415_K	423_H	1.415	0.99
415_K	517_D	1.414	0.99
470_D	533_Y	1.412	0.99
418_N	453_D	1.411	0.99
469_A	473_A	1.403	0.99
282_H	286_E	1.402	0.99
570_S	575_K	1.399	0.99
386_A	458_I	1.395	0.99
576_M	793_F	1.393	0.99
639_I	669_V	1.387	0.99
254_E	258_Q	1.387	0.99
499_I	531_Y	1.387	0.99
701_D	757_E	1.382	0.99
765_K	776_L	1.381	0.99
415_K	418_N	1.381	0.99
744_I	771_K	1.376	0.99
243_F	247_S	1.375	0.99
385_H	388_S	1.372	0.99
559_D	618_E	1.367	0.99
620_C	656_T	1.354	0.99
657_L	695_I	1.349	0.99
414_F	524_K	1.343	0.99
412_N	524_K	1.334	0.99
453_D	524_K	1.330	0.99
564_H	592_L	1.328	0.99
358_M	362_Y	1.326	0.99
617_D	660_Y	1.315	0.99
724_K	758_G	1.310	0.99
414_F	453_D	1.309	0.99
410_D	453_D	1.302	0.99
451_G	521_Y	1.296	0.98
360_K	363_K	1.296	0.98
672_T	701_D	1.288	0.98
786_P	789_Q	1.283	0.98
494_S	529_S	1.278	0.98
587_T	593_R	1.277	0.98
636_A	668_E	1.274	0.98
644_F	649_L	1.266	0.98
386_A	390_L	1.261	0.98
290_K	294_S	1.259	0.98
544_V	590_G	1.259	0.98
328_T	333_F	1.255	0.98
720_L	747_G	1.250	0.98
713_K	729_D	1.249	0.98
264_N	268_I	1.247	0.98
704_T	726_F	1.243	0.98
390_L	509_G	1.243	0.98
653_I	656_T	1.242	0.98
756_A	773_C	1.238	0.98
429_L	484_F	1.228	0.98
730_I	767_L	1.227	0.98
269_F	281_N	1.223	0.98
270_I	281_N	1.219	0.98
620_C	662_L	1.218	0.98
638_N	721_K	1.217	0.98
426_G	453_D	1.209	0.98
418_N	452_G	1.207	0.98
585_L	591_Q	1.206	0.98
656_T	659_K	1.204	0.98
622_Q	791_E	1.200	0.98
236_S	239_A	1.199	0.97
669_V	697_I	1.197	0.97
452_G	517_D	1.196	0.97
789_Q	792_Q	1.194	0.97
486_I	491_L	1.194	0.97
410_D	415_K	1.193	0.97
741_G	749_Q	1.184	0.97
423_H	454_E	1.184	0.97
410_D	517_D	1.183	0.97
560_R	585_L	1.182	0.97
722_I	743_I	1.177	0.97
298_W	303_S	1.170	0.97
410_D	414_F	1.169	0.97
381_P	385_H	1.168	0.97
352_Y	355_C	1.157	0.97
451_G	454_E	1.153	0.97
281_N	353_V	1.148	0.97
409_L	457_I	1.142	0.97
423_H	524_K	1.135	0.97
502_S	512_L	1.131	0.96
730_I	740_T	1.131	0.96
657_L	660_Y	1.129	0.96
442_P	472_L	1.125	0.96
405_V	469_A	1.124	0.96
623_A	635_V	1.118	0.96
336_N	361_Q	1.117	0.96
419_D	452_G	1.116	0.96
270_I	353_V	1.114	0.96
634_S	668_E	1.112	0.96
616_I	656_T	1.111	0.96
505_D	533_Y	1.107	0.96
727_I	756_A	1.106	0.96
776_L	781_F	1.105	0.96
552_L	556_I	1.103	0.96
433_A	480_F	1.102	0.96
291_F	294_S	1.101	0.96
603_E	640_S	1.098	0.96
410_D	521_Y	1.098	0.96
415_K	524_K	1.097	0.96
243_F	246_Q	1.096	0.96
388_S	446_F	1.094	0.96
328_T	332_Q	1.094	0.96
250_I	254_E	1.093	0.96
414_F	418_N	1.087	0.96
480_F	495_V	1.083	0.95
626_W	791_E	1.081	0.95
410_D	423_H	1.081	0.95
731_Q	767_L	1.078	0.95
719_R	755_I	1.076	0.95
496_S	527_N	1.075	0.95
390_L	458_I	1.075	0.95
188_S	192_Y	1.074	0.95
680_L	683_S	1.073	0.95
367_E	370_R	1.073	0.95
605_T	608_I	1.070	0.95
556_I	561_F	1.069	0.95
593_R	600_G	1.068	0.95
240_D	243_F	1.067	0.95
428_Q	487_Q	1.066	0.95
561_F	614_W	1.064	0.95
300_N	325_D	1.064	0.95
722_I	726_F	1.064	0.95
411_L	517_D	1.059	0.95
334_H	359_T	1.058	0.95
672_T	757_E	1.058	0.95
300_N	304_L	1.054	0.95
552_L	602_A	1.052	0.95
741_G	771_K	1.051	0.95
270_I	352_Y	1.049	0.95
415_K	496_S	1.045	0.94
765_K	769_F	1.044	0.94
756_A	768_L	1.043	0.94
437_L	447_I	1.041	0.94
627_H	663_P	1.041	0.94
415_K	454_E	1.040	0.94
341_P	348_L	1.039	0.94
747_G	754_V	1.038	0.94
269_F	284_G	1.037	0.94
616_I	667_L	1.037	0.94
617_D	656_T	1.037	0.94
571_V	765_K	1.036	0.94
717_I	752_L	1.035	0.94
447_I	457_I	1.034	0.94
568_Q	634_S	1.034	0.94
418_N	524_K	1.033	0.94
246_Q	250_I	1.033	0.94
521_Y	524_K	1.029	0.94
450_L	456_I	1.028	0.94
266_D	281_N	1.023	0.94
565_Y	618_E	1.021	0.94
303_S	325_D	1.019	0.94
415_K	419_D	1.019	0.94
562_V	583_I	1.018	0.94
548_Q	585_L	1.012	0.93
684_K	688_S	1.012	0.93
520_M	528_K	1.011	0.93
582_L	701_D	1.010	0.93
672_T	705_G	1.009	0.93
766_Q	770_E	1.004	0.93
364_A	368_I	1.004	0.93
638_N	670_E	1.003	0.93
436_R	484_F	0.997	0.93
456_I	513_M	0.996	0.93
663_P	666_L	0.994	0.93
410_D	418_N	0.994	0.93
602_A	608_I	0.992	0.93
280_S	295_M	0.991	0.93
260_L	352_Y	0.988	0.93
470_D	474_R	0.987	0.93
412_N	528_K	0.987	0.93
485_K	490_T	0.986	0.93
727_I	740_T	0.983	0.92
419_D	423_H	0.981	0.92
261_I	266_D	0.979	0.92
616_I	653_I	0.979	0.92
412_N	521_Y	0.971	0.92
568_Q	636_A	0.969	0.92
662_L	667_L	0.968	0.92
654_K	689_S	0.967	0.92
551_V	589_D	0.965	0.92
339_L	353_V	0.964	0.92
299_R	302_T	0.962	0.92
410_D	496_S	0.960	0.92
481_K	529_S	0.957	0.91
425_V	489_H	0.957	0.91
365_E	369_H	0.956	0.91
419_D	454_E	0.954	0.91
411_L	495_V	0.954	0.91
582_L	638_N	0.951	0.91
593_R	599_I	0.950	0.91
396_R	460_T	0.950	0.91
627_H	630_G	0.949	0.91
565_Y	581_A	0.948	0.91
374_Y	385_H	0.948	0.91
372_A	415_K	0.948	0.91
364_A	371_M	0.947	0.91
453_D	496_S	0.944	0.91
440_V	476_I	0.944	0.91
277_I	297_D	0.943	0.91
271_L	353_V	0.941	0.91
496_S	521_Y	0.940	0.91
548_Q	551_V	0.939	0.91
605_T	609_I	0.937	0.91
281_N	357_D	0.936	0.90
267_A	284_G	0.934	0.90
496_S	524_K	0.934	0.90
145_S	149_A	0.932	0.90
264_N	270_I	0.931	0.90
416_V	549_E	0.930	0.90
270_I	350_S	0.930	0.90
254_E	257_F	0.927	0.90
288_I	326_L	0.927	0.90
421_L	489_H	0.925	0.90
277_I	353_V	0.924	0.90
442_P	475_K	0.922	0.90
757_E	779_F	0.922	0.90
415_K	453_D	0.922	0.90
415_K	452_G	0.921	0.90
704_T	725_S	0.920	0.90
611_I	615_I	0.920	0.90
619_A	637_I	0.919	0.90
414_F	496_S	0.915	0.89
326_L	333_F	0.915	0.89
785_I	793_F	0.914	0.89
644_F	715_F	0.913	0.89
283_A	286_E	0.912	0.89
391_T	509_G	0.911	0.89
613_K	617_D	0.906	0.89
696_R	718_H	0.905	0.89
261_I	281_N	0.904	0.89
423_H	452_G	0.904	0.89
619_A	635_V	0.903	0.89
370_R	379_D	0.899	0.89
746_M	750_L	0.898	0.89
261_I	268_I	0.897	0.89
639_I	643_Q	0.897	0.89
418_N	454_E	0.897	0.89
261_I	264_N	0.896	0.88
299_R	304_L	0.896	0.88
260_L	355_C	0.895	0.88
650_I	690_L	0.895	0.88
582_L	672_T	0.894	0.88
376_S	379_D	0.888	0.88
619_A	667_L	0.886	0.88
595_P	600_G	0.885	0.88
480_F	484_F	0.884	0.88
426_G	452_G	0.877	0.87
599_I	603_E	0.876	0.87
603_E	672_T	0.875	0.87
372_A	521_Y	0.873	0.87
580_E	721_K	0.871	0.87
423_H	453_D	0.868	0.87
650_I	689_S	0.865	0.87
267_A	352_Y	0.865	0.87
556_I	611_I	0.863	0.87
485_K	488_D	0.862	0.86
584_R	595_P	0.861	0.86
372_A	517_D	0.860	0.86
367_E	371_M	0.858	0.86
284_G	353_V	0.855	0.86
527_N	530_K	0.855	0.86
451_G	517_D	0.854	0.86
281_N	359_T	0.854	0.86
620_C	660_Y	0.853	0.86
366_K	369_H	0.852	0.86
496_S	517_D	0.852	0.86
393_V	446_F	0.852	0.86
670_E	721_K	0.852	0.86
415_K	426_G	0.851	0.86
453_D	517_D	0.848	0.86
408_F	456_I	0.847	0.85
551_V	588_P	0.847	0.85
672_T	726_F	0.846	0.85
602_A	606_G	0.846	0.85
389_H	392_K	0.843	0.85
565_Y	626_W	0.842	0.85
617_D	621_K	0.842	0.85
685_K	689_S	0.839	0.85
459_L	469_A	0.839	0.85
596_G	600_G	0.839	0.85
655_D	659_K	0.838	0.85
393_V	460_T	0.837	0.85
609_I	612_G	0.835	0.85
481_K	484_F	0.833	0.85
578_G	634_S	0.832	0.84
224_L	228_C	0.829	0.84
441_V	445_G	0.826	0.84
653_I	669_V	0.825	0.84
741_G	745_A	0.824	0.84
494_S	527_N	0.823	0.84
753_Q	775_H	0.823	0.84
363_K	367_E	0.823	0.84
186_G	191_H	0.821	0.84
325_D	334_H	0.818	0.83
307_K	313_V	0.815	0.83
577_T	775_H	0.815	0.83
342_V	350_S	0.815	0.83
625_I	629_K	0.815	0.83
424_N	510_L	0.814	0.83
454_E	524_K	0.814	0.83
675_M	711_Y	0.809	0.83
411_L	415_K	0.808	0.83
650_I	654_K	0.806	0.83
652_L	656_T	0.806	0.83
595_P	598_F	0.804	0.82
271_L	351_I	0.803	0.82
730_I	737_E	0.803	0.82
501_I	533_Y	0.799	0.82
373_H	384_R	0.799	0.82
613_K	655_D	0.798	0.82
473_A	497_I	0.797	0.82
417_I	426_G	0.796	0.82
406_V	500_A	0.796	0.82
623_A	627_H	0.794	0.82
552_L	555_A	0.794	0.82
425_V	491_L	0.793	0.82
359_T	363_K	0.793	0.82
742_A	749_Q	0.791	0.81
266_D	352_Y	0.790	0.81
377_L	418_N	0.789	0.81
609_I	643_Q	0.788	0.81
650_I	686_V	0.785	0.81
580_E	638_N	0.782	0.81
645_Q	678_D	0.781	0.81
500_A	503_P	0.781	0.81
549_E	643_Q	0.779	0.80
381_P	446_F	0.778	0.80
701_D	726_F	0.777	0.80
414_F	430_L	0.776	0.80
653_I	695_I	0.776	0.80
616_I	669_V	0.775	0.80
326_L	335_L	0.772	0.80
582_L	779_F	0.772	0.80
426_G	517_D	0.771	0.80
668_E	698_S	0.771	0.80
278_I	350_S	0.771	0.80
608_I	640_S	0.769	0.79
260_L	264_N	0.769	0.79
787_P	791_E	0.769	0.79
298_W	301_Y	0.768	0.79
404_T	512_L	0.767	0.79
451_G	496_S	0.763	0.79
653_I	667_L	0.762	0.79
410_D	426_G	0.762	0.79
638_N	760_E	0.760	0.79
477_I	531_Y	0.759	0.79
657_L	664_P	0.758	0.79
258_Q	261_I	0.757	0.78
149_A	153_S	0.754	0.78
503_P	515_K	0.754	0.78
568_Q	755_I	0.753	0.78
423_H	426_G	0.750	0.78
637_I	656_T	0.748	0.78
677_M	683_S	0.748	0.78
394_L	502_S	0.748	0.78
426_G	524_K	0.746	0.77
368_I	371_M	0.745	0.77
253_N	256_R	0.745	0.77
411_L	452_G	0.744	0.77
622_Q	625_I	0.744	0.77
785_I	789_Q	0.742	0.77
258_Q	262_V	0.740	0.77
171_H	174_F	0.739	0.77
535_S	538_I	0.739	0.77
334_H	362_Y	0.739	0.77
729_D	733_H	0.739	0.77
739_I	773_C	0.738	0.77
563_L	618_E	0.737	0.77
571_V	759_V	0.737	0.77
638_N	673_E	0.734	0.76
369_H	373_H	0.733	0.76
260_L	267_A	0.733	0.76
399_S	443_D	0.732	0.76
433_A	484_F	0.732	0.76
638_N	779_F	0.730	0.76
284_G	356_K	0.728	0.76
522_A	526_R	0.728	0.76
377_L	452_G	0.728	0.76
607_L	610_D	0.726	0.75
149_A	152_A	0.726	0.75
321_N	336_N	0.726	0.75
309_L	314_K	0.725	0.75
562_V	788_E	0.725	0.75
502_S	505_D	0.723	0.75
277_I	281_N	0.723	0.75
601_V	605_T	0.723	0.75
547_N	551_V	0.723	0.75
638_N	757_E	0.723	0.75
502_S	506_G	0.722	0.75
783_R	789_Q	0.721	0.75
397_E	502_S	0.720	0.75
574_Q	762_A	0.720	0.75
437_L	657_L	0.718	0.75
260_L	275_G	0.717	0.75
687_L	716_P	0.716	0.74
372_A	429_L	0.715	0.74
457_I	476_I	0.714	0.74
269_F	339_L	0.713	0.74
230_Q	236_S	0.713	0.74
719_R	775_H	0.712	0.74
180_S	186_G	0.710	0.74
149_A	154_F	0.710	0.74
191_H	197_A	0.710	0.74
549_E	601_V	0.709	0.74
256_R	260_L	0.709	0.74
410_D	454_E	0.708	0.74
517_D	524_K	0.707	0.74
260_L	266_D	0.705	0.73
147_I	151_A	0.705	0.73
496_S	528_K	0.704	0.73
619_A	623_A	0.704	0.73
260_L	283_A	0.702	0.73
523_A	530_K	0.701	0.73
143_T	148_I	0.701	0.73
503_P	512_L	0.701	0.73
584_R	757_E	0.700	0.73
333_F	359_T	0.700	0.73
605_T	610_D	0.699	0.73
262_V	742_A	0.698	0.73
593_R	601_V	0.698	0.73
226_I	229_I	0.698	0.73
565_Y	579_A	0.698	0.73
411_L	494_S	0.697	0.72
672_T	779_F	0.697	0.72
638_N	700_D	0.697	0.72
522_A	525_E	0.696	0.72
620_C	764_Q	0.695	0.72
657_L	693_L	0.695	0.72
542_E	546_L	0.694	0.72
378_T	430_L	0.694	0.72
650_I	693_L	0.693	0.72
556_I	583_I	0.693	0.72
625_I	628_D	0.691	0.72
267_A	351_I	0.690	0.72
147_I	150_I	0.690	0.72
522_A	532_R	0.690	0.72
500_A	506_G	0.689	0.72
454_E	521_Y	0.688	0.72
610_D	643_Q	0.687	0.71
701_D	779_F	0.687	0.71
736_S	764_Q	0.687	0.71
709_L	726_F	0.686	0.71
603_E	726_F	0.686	0.71
372_A	452_G	0.686	0.71
616_I	652_L	0.685	0.71
621_K	625_I	0.685	0.71
324_S	335_L	0.684	0.71
636_A	719_R	0.683	0.71
421_L	425_V	0.683	0.71
562_V	593_R	0.681	0.71
490_T	554_E	0.681	0.71
269_F	352_Y	0.681	0.71
446_F	458_I	0.680	0.71
418_N	430_L	0.678	0.70
412_N	529_S	0.678	0.70
440_V	475_K	0.678	0.70
260_L	270_I	0.676	0.70
257_F	279_S	0.676	0.70
261_I	269_F	0.675	0.70
412_N	419_D	0.675	0.70
608_I	672_T	0.675	0.70
261_I	270_I	0.674	0.70
754_V	772_G	0.674	0.70
439_S	479_K	0.673	0.70
568_Q	699_I	0.673	0.70
588_P	592_L	0.672	0.70
720_L	752_L	0.672	0.70
402_Y	461_D	0.669	0.69
221_F	225_I	0.668	0.69
582_L	721_K	0.668	0.69
582_L	595_P	0.667	0.69
421_L	491_L	0.665	0.69
282_H	285_E	0.664	0.69
787_P	790_F	0.664	0.69
582_L	670_E	0.663	0.69
411_L	423_H	0.662	0.69
268_I	279_S	0.662	0.69
562_V	786_P	0.661	0.68
672_T	706_H	0.660	0.68
409_L	497_I	0.659	0.68
324_S	337_I	0.658	0.68
556_I	559_D	0.657	0.68
234_L	238_H	0.657	0.68
731_Q	764_Q	0.656	0.68
146_I	150_I	0.656	0.68
281_N	356_K	0.655	0.68
227_F	230_Q	0.654	0.68
738_Q	746_M	0.652	0.67
404_T	502_S	0.651	0.67
280_S	284_G	0.651	0.67
260_L	350_S	0.648	0.67
584_R	638_N	0.647	0.67
779_F	783_R	0.646	0.67
385_H	393_V	0.645	0.67
672_T	704_T	0.645	0.67
668_E	696_R	0.645	0.67
389_H	448_A	0.645	0.67
721_K	757_E	0.644	0.66
392_K	399_S	0.644	0.66
220_I	228_C	0.643	0.66
623_A	660_Y	0.642	0.66
259_S	269_F	0.642	0.66
707_S	726_F	0.641	0.66
713_K	733_H	0.641	0.66
708_S	726_F	0.640	0.66
445_G	475_K	0.640	0.66
474_R	531_Y	0.639	0.66
394_L	404_T	0.639	0.66
263_H	352_Y	0.639	0.66
375_D	449_R	0.637	0.66
590_G	593_R	0.637	0.66
578_G	633_L	0.636	0.65
259_S	352_Y	0.636	0.65
429_L	486_I	0.636	0.65
415_K	520_M	0.635	0.65
511_E	515_K	0.635	0.65
758_G	764_Q	0.635	0.65
549_E	605_T	0.634	0.65
270_I	283_A	0.634	0.65
454_E	496_S	0.633	0.65
599_I	612_G	0.633	0.65
418_N	496_S	0.633	0.65
448_A	513_M	0.633	0.65
641_A	671_V	0.632	0.65
289_S	331_G	0.631	0.65
600_G	614_W	0.631	0.65
393_V	404_T	0.630	0.65
415_K	528_K	0.630	0.65
281_N	323_D	0.629	0.65
506_G	511_E	0.629	0.65
440_V	472_L	0.628	0.65
559_D	617_D	0.627	0.64
710_S	725_S	0.625	0.64
262_V	266_D	0.625	0.64
193_T	200_F	0.624	0.64
344_V	347_E	0.624	0.64
640_S	672_T	0.623	0.64
423_H	451_G	0.623	0.64
251_K	254_E	0.622	0.64
266_D	355_C	0.621	0.64
498_G	519_A	0.621	0.64
267_A	283_A	0.621	0.64
335_L	359_T	0.621	0.64
323_D	361_Q	0.621	0.64
637_I	695_I	0.620	0.64
581_A	619_A	0.619	0.63
386_A	406_V	0.619	0.63
257_F	266_D	0.618	0.63
412_N	517_D	0.617	0.63
407_F	457_I	0.617	0.63
159_I	162_D	0.616	0.63
281_N	287_M	0.616	0.63
320_M	339_L	0.616	0.63
608_I	612_G	0.616	0.63
624_R	627_H	0.615	0.63
145_S	148_I	0.615	0.63
413_R	604_E	0.614	0.63
414_F	426_G	0.613	0.63
580_E	777_Q	0.612	0.63
744_I	748_H	0.612	0.63
334_H	358_M	0.612	0.63
441_V	457_I	0.611	0.62
570_S	774_D	0.611	0.62
144_V	149_A	0.610	0.62
405_V	499_I	0.610	0.62
579_A	635_V	0.609	0.62
630_G	666_L	0.609	0.62
191_H	195_M	0.609	0.62
253_N	258_Q	0.608	0.62
449_R	452_G	0.606	0.62
247_S	250_I	0.604	0.62
566_Q	582_L	0.604	0.62
551_V	585_L	0.603	0.61
428_Q	432_F	0.603	0.61
609_I	646_S	0.603	0.61
426_G	521_Y	0.603	0.61
371_M	568_Q	0.601	0.61
473_A	531_Y	0.601	0.61
415_K	451_G	0.600	0.61
267_A	278_I	0.600	0.61
668_E	775_H	0.600	0.61
145_S	152_A	0.600	0.61
353_V	356_K	0.598	0.61
290_K	335_L	0.598	0.61
386_A	450_L	0.597	0.61
728_D	764_Q	0.595	0.60
261_I	352_Y	0.595	0.60
713_K	739_I	0.595	0.60
216_F	228_C	0.594	0.60
744_I	768_L	0.593	0.60
285_E	292_G	0.593	0.60
271_L	277_I	0.592	0.60
343_E	348_L	0.591	0.60
281_N	352_Y	0.591	0.60
260_L	354_I	0.591	0.60
199_T	203_D	0.591	0.60
670_E	700_D	0.590	0.60
472_L	475_K	0.590	0.60
187_I	195_M	0.588	0.59
249_R	252_D	0.588	0.59
721_K	777_Q	0.587	0.59
442_P	462_A	0.586	0.59
151_A	158_K	0.586	0.59
608_I	643_Q	0.585	0.59
410_D	419_D	0.584	0.59
418_N	427_D	0.583	0.59
383_R	423_H	0.582	0.59
306_V	314_K	0.582	0.59
143_T	146_I	0.581	0.59
638_N	701_D	0.581	0.59
477_I	529_S	0.581	0.59
594_P	597_E	0.580	0.58
526_R	530_K	0.580	0.58
149_A	157_L	0.579	0.58
484_F	493_T	0.578	0.58
148_I	152_A	0.577	0.58
412_N	527_N	0.577	0.58
463_N	468_E	0.577	0.58
186_G	198_A	0.577	0.58
662_L	695_I	0.576	0.58
281_N	284_G	0.576	0.58
762_A	765_K	0.575	0.58
583_I	592_L	0.573	0.58
682_H	686_V	0.572	0.57
585_L	773_C	0.572	0.57
524_K	528_K	0.572	0.57
418_N	451_G	0.572	0.57
708_S	760_E	0.571	0.57
397_E	503_P	0.570	0.57
328_T	335_L	0.570	0.57
394_L	506_G	0.569	0.57
759_V	768_L	0.569	0.57
671_V	746_M	0.569	0.57
279_S	282_H	0.569	0.57
745_A	749_Q	0.569	0.57
522_A	538_I	0.569	0.57
518_M	542_E	0.568	0.57
305_K	309_L	0.568	0.57
764_Q	780_F	0.568	0.57
586_V	590_G	0.567	0.57
425_V	486_I	0.567	0.57
234_L	237_S	0.567	0.57
566_Q	721_K	0.567	0.57
584_R	670_E	0.566	0.57
317_K	320_M	0.565	0.56
219_S	228_C	0.565	0.56
704_T	709_L	0.564	0.56
553_R	607_L	0.564	0.56
305_K	310_F	0.564	0.56
410_D	451_G	0.564	0.56
399_S	445_G	0.563	0.56
348_L	352_Y	0.563	0.56
782_S	793_F	0.563	0.56
392_K	442_P	0.563	0.56
247_S	251_K	0.562	0.56
766_Q	769_F	0.562	0.56
730_I	768_L	0.562	0.56
414_F	517_D	0.562	0.56
566_Q	584_R	0.562	0.56
235_F	239_A	0.561	0.56
711_Y	726_F	0.560	0.56
721_K	779_F	0.560	0.56
657_L	667_L	0.560	0.56
426_G	496_S	0.559	0.56
423_H	496_S	0.559	0.56
677_M	680_L	0.559	0.56
496_S	520_M	0.559	0.56
370_R	373_H	0.558	0.56
236_S	240_D	0.558	0.56
676_T	706_H	0.558	0.56
470_D	499_I	0.557	0.55
705_G	726_F	0.557	0.55
505_D	515_K	0.556	0.55
672_T	711_Y	0.555	0.55
418_N	517_D	0.555	0.55
144_V	162_D	0.554	0.55
579_A	633_L	0.554	0.55
606_G	667_L	0.553	0.55
365_E	368_I	0.552	0.55
505_D	512_L	0.551	0.55
453_D	528_K	0.551	0.55
688_S	716_P	0.551	0.55
580_E	670_E	0.551	0.55
152_A	164_A	0.551	0.55
395_N	399_S	0.550	0.54
582_L	757_E	0.549	0.54
412_N	415_K	0.549	0.54
260_L	356_K	0.548	0.54
755_I	775_H	0.548	0.54
377_L	427_D	0.548	0.54
566_Q	638_N	0.548	0.54
403_N	504_K	0.548	0.54
265_I	352_Y	0.548	0.54
673_E	700_D	0.548	0.54
388_S	392_K	0.547	0.54
257_F	352_Y	0.547	0.54
268_I	285_E	0.547	0.54
421_L	546_L	0.546	0.54
322_S	325_D	0.546	0.54
379_D	431_Q	0.546	0.54
520_M	668_E	0.546	0.54
150_I	154_F	0.546	0.54
580_E	673_E	0.546	0.54
425_V	428_Q	0.545	0.54
680_L	715_F	0.545	0.54
373_H	388_S	0.545	0.54
700_D	721_K	0.544	0.54
424_N	520_M	0.544	0.54
790_F	793_F	0.544	0.54
383_R	454_E	0.544	0.54
583_I	643_Q	0.544	0.54
779_F	782_S	0.543	0.54
520_M	524_K	0.543	0.54
225_I	230_Q	0.543	0.54
492_V	553_R	0.542	0.53
706_H	711_Y	0.541	0.53
605_T	642_R	0.540	0.53
410_D	427_D	0.539	0.53
280_S	288_I	0.539	0.53
153_S	156_S	0.538	0.53
257_F	265_I	0.538	0.53
266_D	283_A	0.537	0.53
417_I	491_L	0.537	0.53
260_L	279_S	0.537	0.53
642_R	781_F	0.537	0.53
672_T	707_S	0.537	0.53
310_F	314_K	0.535	0.52
642_R	675_M	0.535	0.52
720_L	743_I	0.535	0.52
426_G	454_E	0.535	0.52
265_I	355_C	0.534	0.52
192_Y	196_L	0.534	0.52
705_G	708_S	0.534	0.52
707_S	711_Y	0.534	0.52
219_S	225_I	0.532	0.52
210_H	223_T	0.532	0.52
418_N	423_H	0.532	0.52
561_F	607_L	0.531	0.52
372_A	410_D	0.531	0.52
414_F	419_D	0.531	0.52
339_L	752_L	0.531	0.52
298_W	302_T	0.531	0.52
723_D	757_E	0.530	0.52
414_F	452_G	0.530	0.52
389_H	460_T	0.530	0.52
445_G	460_T	0.530	0.52
266_D	354_I	0.529	0.52
737_E	741_G	0.528	0.52
515_K	539_G	0.527	0.51
413_R	534_Y	0.526	0.51
721_K	760_E	0.526	0.51
414_F	423_H	0.526	0.51
603_E	674_S	0.526	0.51
430_L	453_D	0.526	0.51
539_G	790_F	0.525	0.51
414_F	454_E	0.524	0.51
585_L	598_F	0.524	0.51
214_Q	218_W	0.523	0.51
579_A	623_A	0.523	0.51
709_L	758_G	0.523	0.51
189_G	201_H	0.522	0.51
539_G	543_T	0.522	0.51
148_I	153_S	0.521	0.51
711_Y	714_D	0.521	0.51
412_N	494_S	0.520	0.50
518_M	538_I	0.520	0.50
427_D	524_K	0.519	0.50
612_G	704_T	0.519	0.50
554_E	557_E	0.519	0.50
153_S	164_A	0.519	0.50
350_S	353_V	0.519	0.50
599_I	640_S	0.518	0.50
145_S	157_L	0.517	0.50
260_L	268_I	0.517	0.50
383_R	451_G	0.517	0.50
156_S	162_D	0.517	0.50
172_L	177_G	0.516	0.50
582_L	700_D	0.515	0.50
346_Q	349_D	0.515	0.50
556_I	709_L	0.514	0.50
269_F	280_S	0.513	0.50
172_L	176_K	0.512	0.49
408_F	415_K	0.512	0.49
154_F	161_F	0.511	0.49
624_R	660_Y	0.510	0.49
213_V	223_T	0.510	0.49
253_N	257_F	0.510	0.49
153_S	159_I	0.510	0.49
552_L	601_V	0.510	0.49
261_I	283_A	0.509	0.49
610_D	727_I	0.509	0.49
368_I	373_H	0.508	0.49
218_W	230_Q	0.508	0.49
255_Q	259_S	0.508	0.49
270_I	279_S	0.508	0.49
566_Q	670_E	0.507	0.49
152_A	159_I	0.507	0.49
266_D	271_L	0.507	0.49
705_G	757_E	0.507	0.49
380_L	434_A	0.507	0.49
451_G	524_K	0.506	0.49
388_S	391_T	0.506	0.49
171_H	181_I	0.506	0.49
419_D	451_G	0.505	0.48
266_D	334_H	0.503	0.48
187_I	200_F	0.503	0.48
179_S	190_M	0.502	0.48
410_D	452_G	0.501	0.48
708_S	757_E	0.501	0.48
641_A	644_F	0.500	0.48

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4rnhA	2	0.5225	100	0.398	Contact Map
4j40A	2	0.3137	100	0.404	Contact Map
3pjxA	1	0.5225	100	0.425	Contact Map
3gfzA	2	0.4738	100	0.497	Contact Map
4hjfA	1	0.3237	100	0.532	Contact Map
4hu4A	1	0.3063	100	0.607	Contact Map
4kieA	1	0.325	100	0.608	Contact Map
3sy8A	6	0.4925	100	0.609	Contact Map
2r6oA	2	0.32	100	0.611	Contact Map
4rniA	2	0.3162	100	0.615	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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