GREMLIN Database
YKOW - Signaling protein YkoW
UniProt: O34311 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 800 (645)
Sequences: 2633 (2173)
Seq/√Len: 85.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
579_A790_F5.5171.00
782_S785_I4.9151.00
617_D659_K4.8461.00
442_P445_G4.7171.00
724_K728_D4.4041.00
370_R374_Y4.3951.00
612_G643_Q4.0891.00
571_V776_L4.0621.00
691_T718_H3.9681.00
544_V597_E3.8771.00
759_V776_L3.7511.00
656_T660_Y3.6521.00
570_S573_K3.5721.00
587_T591_Q3.4331.00
639_I649_L3.3651.00
299_R303_S3.2871.00
407_F497_I3.2821.00
654_K693_L3.2431.00
508_D511_E3.0611.00
441_V447_I3.0551.00
748_H774_D3.0371.00
565_Y622_Q3.0241.00
618_E621_K2.9831.00
613_K652_L2.9731.00
713_K736_S2.9451.00
583_I611_I2.9381.00
266_D356_K2.8241.00
503_P506_G2.8201.00
563_L614_W2.7401.00
562_V586_V2.7151.00
587_T590_G2.6341.00
564_H786_P2.6341.00
551_V587_T2.6251.00
386_A456_I2.5711.00
409_L495_V2.4781.00
389_H446_F2.4461.00
583_I615_I2.3991.00
767_L771_K2.3311.00
588_P591_Q2.2841.00
561_F583_I2.2611.00
385_H389_H2.2451.00
762_A766_Q2.2351.00
385_H446_F2.2341.00
361_Q365_E2.2111.00
269_F353_V2.1791.00
569_F781_F2.1301.00
459_L472_L2.1251.00
623_A662_L2.1251.00
622_Q626_W2.1191.00
687_L697_I2.1111.00
300_N303_S2.1101.00
407_F473_A2.0721.00
583_I614_W2.0581.00
551_V590_G2.0501.00
336_N356_K2.0151.00
267_A287_M2.0041.00
668_E719_R2.0001.00
552_L561_F1.9841.00
627_H666_L1.9821.00
626_W787_P1.9801.00
765_K780_F1.9691.00
323_D362_Y1.9451.00
506_G515_K1.9441.00
622_Q787_P1.9341.00
563_L583_I1.9331.00
568_Q775_H1.9171.00
568_Q578_G1.9161.00
267_A281_N1.9111.00
267_A355_C1.9071.00
649_L653_I1.9031.00
418_N426_G1.8911.00
637_I667_L1.8731.00
499_I533_Y1.8571.00
294_S329_E1.8511.00
473_A499_I1.8421.00
731_Q763_A1.8421.00
410_D524_K1.8351.00
413_R528_K1.8261.00
731_Q737_E1.8221.00
419_D517_D1.8101.00
362_Y365_E1.8051.00
405_V501_I1.7971.00
452_G521_Y1.7851.00
477_I497_I1.7771.00
408_F520_M1.7741.00
432_F435_K1.7541.00
765_K781_F1.7481.00
602_A611_I1.7301.00
517_D521_Y1.7211.00
657_L662_L1.7181.00
412_N496_S1.7171.00
419_D521_Y1.7081.00
562_V592_L1.7001.00
620_C667_L1.6961.00
290_K329_E1.6941.00
454_E517_D1.6931.00
563_L615_I1.6811.00
641_A674_S1.6811.00
548_Q601_V1.6801.00
753_Q774_D1.6721.00
549_E553_R1.6671.00
748_H754_V1.6611.00
272_S276_D1.6381.00
474_R478_Q1.6371.00
545_K604_E1.6371.00
560_R587_T1.6321.00
399_S442_P1.6311.00
411_L433_A1.6191.00
614_W618_E1.6171.00
428_Q431_Q1.6171.00
261_I279_S1.6121.00
225_I228_C1.6081.00
423_H517_D1.6071.00
415_K521_Y1.6071.00
257_F260_L1.6071.00
599_I608_I1.6061.00
761_N764_Q1.6021.00
618_E622_Q1.5991.00
586_V592_L1.5951.00
341_P350_S1.5851.00
699_I717_I1.5841.00
284_G288_I1.5801.00
594_P600_G1.5601.00
417_I429_L1.5521.00
667_L695_I1.5521.00
560_R588_P1.5481.00
413_R549_E1.5461.00
554_E558_N1.5421.00
435_K438_S1.5361.00
698_S719_R1.5341.00
739_I746_M1.5321.00
563_L619_A1.5301.00
644_F687_L1.5261.00
779_F784_P1.5261.00
269_F277_I1.5191.00
423_H521_Y1.5171.00
599_I672_T1.5131.00
624_R628_D1.5111.00
239_A243_F1.5111.00
526_R532_R1.5030.99
653_I690_L1.5010.99
257_F261_I1.5000.99
762_A780_F1.4660.99
737_E767_L1.4630.99
744_I773_C1.4620.99
432_F436_R1.4580.99
616_I637_I1.4560.99
386_A448_A1.4500.99
596_G724_K1.4460.99
568_Q668_E1.4360.99
634_S696_R1.4350.99
603_E608_I1.4330.99
590_G597_E1.4320.99
436_R483_P1.4300.99
554_E560_R1.4270.99
429_L493_T1.4210.99
432_F484_F1.4190.99
568_Q719_R1.4160.99
415_K423_H1.4150.99
415_K517_D1.4140.99
470_D533_Y1.4120.99
418_N453_D1.4110.99
469_A473_A1.4030.99
282_H286_E1.4020.99
570_S575_K1.3990.99
386_A458_I1.3950.99
576_M793_F1.3930.99
639_I669_V1.3870.99
254_E258_Q1.3870.99
499_I531_Y1.3870.99
701_D757_E1.3820.99
765_K776_L1.3810.99
415_K418_N1.3810.99
744_I771_K1.3760.99
243_F247_S1.3750.99
385_H388_S1.3720.99
559_D618_E1.3670.99
620_C656_T1.3540.99
657_L695_I1.3490.99
414_F524_K1.3430.99
412_N524_K1.3340.99
453_D524_K1.3300.99
564_H592_L1.3280.99
358_M362_Y1.3260.99
617_D660_Y1.3150.99
724_K758_G1.3100.99
414_F453_D1.3090.99
410_D453_D1.3020.99
451_G521_Y1.2960.98
360_K363_K1.2960.98
672_T701_D1.2880.98
786_P789_Q1.2830.98
494_S529_S1.2780.98
587_T593_R1.2770.98
636_A668_E1.2740.98
644_F649_L1.2660.98
386_A390_L1.2610.98
290_K294_S1.2590.98
544_V590_G1.2590.98
328_T333_F1.2550.98
720_L747_G1.2500.98
713_K729_D1.2490.98
264_N268_I1.2470.98
704_T726_F1.2430.98
390_L509_G1.2430.98
653_I656_T1.2420.98
756_A773_C1.2380.98
429_L484_F1.2280.98
730_I767_L1.2270.98
269_F281_N1.2230.98
270_I281_N1.2190.98
620_C662_L1.2180.98
638_N721_K1.2170.98
426_G453_D1.2090.98
418_N452_G1.2070.98
585_L591_Q1.2060.98
656_T659_K1.2040.98
622_Q791_E1.2000.98
236_S239_A1.1990.97
669_V697_I1.1970.97
452_G517_D1.1960.97
789_Q792_Q1.1940.97
486_I491_L1.1940.97
410_D415_K1.1930.97
741_G749_Q1.1840.97
423_H454_E1.1840.97
410_D517_D1.1830.97
560_R585_L1.1820.97
722_I743_I1.1770.97
298_W303_S1.1700.97
410_D414_F1.1690.97
381_P385_H1.1680.97
352_Y355_C1.1570.97
451_G454_E1.1530.97
281_N353_V1.1480.97
409_L457_I1.1420.97
423_H524_K1.1350.97
502_S512_L1.1310.96
730_I740_T1.1310.96
657_L660_Y1.1290.96
442_P472_L1.1250.96
405_V469_A1.1240.96
623_A635_V1.1180.96
336_N361_Q1.1170.96
419_D452_G1.1160.96
270_I353_V1.1140.96
634_S668_E1.1120.96
616_I656_T1.1110.96
505_D533_Y1.1070.96
727_I756_A1.1060.96
776_L781_F1.1050.96
552_L556_I1.1030.96
433_A480_F1.1020.96
291_F294_S1.1010.96
603_E640_S1.0980.96
410_D521_Y1.0980.96
415_K524_K1.0970.96
243_F246_Q1.0960.96
388_S446_F1.0940.96
328_T332_Q1.0940.96
250_I254_E1.0930.96
414_F418_N1.0870.96
480_F495_V1.0830.95
626_W791_E1.0810.95
410_D423_H1.0810.95
731_Q767_L1.0780.95
719_R755_I1.0760.95
496_S527_N1.0750.95
390_L458_I1.0750.95
188_S192_Y1.0740.95
680_L683_S1.0730.95
367_E370_R1.0730.95
605_T608_I1.0700.95
556_I561_F1.0690.95
593_R600_G1.0680.95
240_D243_F1.0670.95
428_Q487_Q1.0660.95
561_F614_W1.0640.95
300_N325_D1.0640.95
722_I726_F1.0640.95
411_L517_D1.0590.95
334_H359_T1.0580.95
672_T757_E1.0580.95
300_N304_L1.0540.95
552_L602_A1.0520.95
741_G771_K1.0510.95
270_I352_Y1.0490.95
415_K496_S1.0450.94
765_K769_F1.0440.94
756_A768_L1.0430.94
437_L447_I1.0410.94
627_H663_P1.0410.94
415_K454_E1.0400.94
341_P348_L1.0390.94
747_G754_V1.0380.94
269_F284_G1.0370.94
616_I667_L1.0370.94
617_D656_T1.0370.94
571_V765_K1.0360.94
717_I752_L1.0350.94
447_I457_I1.0340.94
568_Q634_S1.0340.94
418_N524_K1.0330.94
246_Q250_I1.0330.94
521_Y524_K1.0290.94
450_L456_I1.0280.94
266_D281_N1.0230.94
565_Y618_E1.0210.94
303_S325_D1.0190.94
415_K419_D1.0190.94
562_V583_I1.0180.94
548_Q585_L1.0120.93
684_K688_S1.0120.93
520_M528_K1.0110.93
582_L701_D1.0100.93
672_T705_G1.0090.93
766_Q770_E1.0040.93
364_A368_I1.0040.93
638_N670_E1.0030.93
436_R484_F0.9970.93
456_I513_M0.9960.93
663_P666_L0.9940.93
410_D418_N0.9940.93
602_A608_I0.9920.93
280_S295_M0.9910.93
260_L352_Y0.9880.93
470_D474_R0.9870.93
412_N528_K0.9870.93
485_K490_T0.9860.93
727_I740_T0.9830.92
419_D423_H0.9810.92
261_I266_D0.9790.92
616_I653_I0.9790.92
412_N521_Y0.9710.92
568_Q636_A0.9690.92
662_L667_L0.9680.92
654_K689_S0.9670.92
551_V589_D0.9650.92
339_L353_V0.9640.92
299_R302_T0.9620.92
410_D496_S0.9600.92
481_K529_S0.9570.91
425_V489_H0.9570.91
365_E369_H0.9560.91
419_D454_E0.9540.91
411_L495_V0.9540.91
582_L638_N0.9510.91
593_R599_I0.9500.91
396_R460_T0.9500.91
627_H630_G0.9490.91
565_Y581_A0.9480.91
374_Y385_H0.9480.91
372_A415_K0.9480.91
364_A371_M0.9470.91
453_D496_S0.9440.91
440_V476_I0.9440.91
277_I297_D0.9430.91
271_L353_V0.9410.91
496_S521_Y0.9400.91
548_Q551_V0.9390.91
605_T609_I0.9370.91
281_N357_D0.9360.90
267_A284_G0.9340.90
496_S524_K0.9340.90
145_S149_A0.9320.90
264_N270_I0.9310.90
416_V549_E0.9300.90
270_I350_S0.9300.90
254_E257_F0.9270.90
288_I326_L0.9270.90
421_L489_H0.9250.90
277_I353_V0.9240.90
442_P475_K0.9220.90
757_E779_F0.9220.90
415_K453_D0.9220.90
415_K452_G0.9210.90
704_T725_S0.9200.90
611_I615_I0.9200.90
619_A637_I0.9190.90
414_F496_S0.9150.89
326_L333_F0.9150.89
785_I793_F0.9140.89
644_F715_F0.9130.89
283_A286_E0.9120.89
391_T509_G0.9110.89
613_K617_D0.9060.89
696_R718_H0.9050.89
261_I281_N0.9040.89
423_H452_G0.9040.89
619_A635_V0.9030.89
370_R379_D0.8990.89
746_M750_L0.8980.89
261_I268_I0.8970.89
639_I643_Q0.8970.89
418_N454_E0.8970.89
261_I264_N0.8960.88
299_R304_L0.8960.88
260_L355_C0.8950.88
650_I690_L0.8950.88
582_L672_T0.8940.88
376_S379_D0.8880.88
619_A667_L0.8860.88
595_P600_G0.8850.88
480_F484_F0.8840.88
426_G452_G0.8770.87
599_I603_E0.8760.87
603_E672_T0.8750.87
372_A521_Y0.8730.87
580_E721_K0.8710.87
423_H453_D0.8680.87
650_I689_S0.8650.87
267_A352_Y0.8650.87
556_I611_I0.8630.87
485_K488_D0.8620.86
584_R595_P0.8610.86
372_A517_D0.8600.86
367_E371_M0.8580.86
284_G353_V0.8550.86
527_N530_K0.8550.86
451_G517_D0.8540.86
281_N359_T0.8540.86
620_C660_Y0.8530.86
366_K369_H0.8520.86
496_S517_D0.8520.86
393_V446_F0.8520.86
670_E721_K0.8520.86
415_K426_G0.8510.86
453_D517_D0.8480.86
408_F456_I0.8470.85
551_V588_P0.8470.85
672_T726_F0.8460.85
602_A606_G0.8460.85
389_H392_K0.8430.85
565_Y626_W0.8420.85
617_D621_K0.8420.85
685_K689_S0.8390.85
459_L469_A0.8390.85
596_G600_G0.8390.85
655_D659_K0.8380.85
393_V460_T0.8370.85
609_I612_G0.8350.85
481_K484_F0.8330.85
578_G634_S0.8320.84
224_L228_C0.8290.84
441_V445_G0.8260.84
653_I669_V0.8250.84
741_G745_A0.8240.84
494_S527_N0.8230.84
753_Q775_H0.8230.84
363_K367_E0.8230.84
186_G191_H0.8210.84
325_D334_H0.8180.83
307_K313_V0.8150.83
577_T775_H0.8150.83
342_V350_S0.8150.83
625_I629_K0.8150.83
424_N510_L0.8140.83
454_E524_K0.8140.83
675_M711_Y0.8090.83
411_L415_K0.8080.83
650_I654_K0.8060.83
652_L656_T0.8060.83
595_P598_F0.8040.82
271_L351_I0.8030.82
730_I737_E0.8030.82
501_I533_Y0.7990.82
373_H384_R0.7990.82
613_K655_D0.7980.82
473_A497_I0.7970.82
417_I426_G0.7960.82
406_V500_A0.7960.82
623_A627_H0.7940.82
552_L555_A0.7940.82
425_V491_L0.7930.82
359_T363_K0.7930.82
742_A749_Q0.7910.81
266_D352_Y0.7900.81
377_L418_N0.7890.81
609_I643_Q0.7880.81
650_I686_V0.7850.81
580_E638_N0.7820.81
645_Q678_D0.7810.81
500_A503_P0.7810.81
549_E643_Q0.7790.80
381_P446_F0.7780.80
701_D726_F0.7770.80
414_F430_L0.7760.80
653_I695_I0.7760.80
616_I669_V0.7750.80
326_L335_L0.7720.80
582_L779_F0.7720.80
426_G517_D0.7710.80
668_E698_S0.7710.80
278_I350_S0.7710.80
608_I640_S0.7690.79
260_L264_N0.7690.79
787_P791_E0.7690.79
298_W301_Y0.7680.79
404_T512_L0.7670.79
451_G496_S0.7630.79
653_I667_L0.7620.79
410_D426_G0.7620.79
638_N760_E0.7600.79
477_I531_Y0.7590.79
657_L664_P0.7580.79
258_Q261_I0.7570.78
149_A153_S0.7540.78
503_P515_K0.7540.78
568_Q755_I0.7530.78
423_H426_G0.7500.78
637_I656_T0.7480.78
677_M683_S0.7480.78
394_L502_S0.7480.78
426_G524_K0.7460.77
368_I371_M0.7450.77
253_N256_R0.7450.77
411_L452_G0.7440.77
622_Q625_I0.7440.77
785_I789_Q0.7420.77
258_Q262_V0.7400.77
171_H174_F0.7390.77
535_S538_I0.7390.77
334_H362_Y0.7390.77
729_D733_H0.7390.77
739_I773_C0.7380.77
563_L618_E0.7370.77
571_V759_V0.7370.77
638_N673_E0.7340.76
369_H373_H0.7330.76
260_L267_A0.7330.76
399_S443_D0.7320.76
433_A484_F0.7320.76
638_N779_F0.7300.76
284_G356_K0.7280.76
522_A526_R0.7280.76
377_L452_G0.7280.76
607_L610_D0.7260.75
149_A152_A0.7260.75
321_N336_N0.7260.75
309_L314_K0.7250.75
562_V788_E0.7250.75
502_S505_D0.7230.75
277_I281_N0.7230.75
601_V605_T0.7230.75
547_N551_V0.7230.75
638_N757_E0.7230.75
502_S506_G0.7220.75
783_R789_Q0.7210.75
397_E502_S0.7200.75
574_Q762_A0.7200.75
437_L657_L0.7180.75
260_L275_G0.7170.75
687_L716_P0.7160.74
372_A429_L0.7150.74
457_I476_I0.7140.74
269_F339_L0.7130.74
230_Q236_S0.7130.74
719_R775_H0.7120.74
180_S186_G0.7100.74
149_A154_F0.7100.74
191_H197_A0.7100.74
549_E601_V0.7090.74
256_R260_L0.7090.74
410_D454_E0.7080.74
517_D524_K0.7070.74
260_L266_D0.7050.73
147_I151_A0.7050.73
496_S528_K0.7040.73
619_A623_A0.7040.73
260_L283_A0.7020.73
523_A530_K0.7010.73
143_T148_I0.7010.73
503_P512_L0.7010.73
584_R757_E0.7000.73
333_F359_T0.7000.73
605_T610_D0.6990.73
262_V742_A0.6980.73
593_R601_V0.6980.73
226_I229_I0.6980.73
565_Y579_A0.6980.73
411_L494_S0.6970.72
672_T779_F0.6970.72
638_N700_D0.6970.72
522_A525_E0.6960.72
620_C764_Q0.6950.72
657_L693_L0.6950.72
542_E546_L0.6940.72
378_T430_L0.6940.72
650_I693_L0.6930.72
556_I583_I0.6930.72
625_I628_D0.6910.72
267_A351_I0.6900.72
147_I150_I0.6900.72
522_A532_R0.6900.72
500_A506_G0.6890.72
454_E521_Y0.6880.72
610_D643_Q0.6870.71
701_D779_F0.6870.71
736_S764_Q0.6870.71
709_L726_F0.6860.71
603_E726_F0.6860.71
372_A452_G0.6860.71
616_I652_L0.6850.71
621_K625_I0.6850.71
324_S335_L0.6840.71
636_A719_R0.6830.71
421_L425_V0.6830.71
562_V593_R0.6810.71
490_T554_E0.6810.71
269_F352_Y0.6810.71
446_F458_I0.6800.71
418_N430_L0.6780.70
412_N529_S0.6780.70
440_V475_K0.6780.70
260_L270_I0.6760.70
257_F279_S0.6760.70
261_I269_F0.6750.70
412_N419_D0.6750.70
608_I672_T0.6750.70
261_I270_I0.6740.70
754_V772_G0.6740.70
439_S479_K0.6730.70
568_Q699_I0.6730.70
588_P592_L0.6720.70
720_L752_L0.6720.70
402_Y461_D0.6690.69
221_F225_I0.6680.69
582_L721_K0.6680.69
582_L595_P0.6670.69
421_L491_L0.6650.69
282_H285_E0.6640.69
787_P790_F0.6640.69
582_L670_E0.6630.69
411_L423_H0.6620.69
268_I279_S0.6620.69
562_V786_P0.6610.68
672_T706_H0.6600.68
409_L497_I0.6590.68
324_S337_I0.6580.68
556_I559_D0.6570.68
234_L238_H0.6570.68
731_Q764_Q0.6560.68
146_I150_I0.6560.68
281_N356_K0.6550.68
227_F230_Q0.6540.68
738_Q746_M0.6520.67
404_T502_S0.6510.67
280_S284_G0.6510.67
260_L350_S0.6480.67
584_R638_N0.6470.67
779_F783_R0.6460.67
385_H393_V0.6450.67
672_T704_T0.6450.67
668_E696_R0.6450.67
389_H448_A0.6450.67
721_K757_E0.6440.66
392_K399_S0.6440.66
220_I228_C0.6430.66
623_A660_Y0.6420.66
259_S269_F0.6420.66
707_S726_F0.6410.66
713_K733_H0.6410.66
708_S726_F0.6400.66
445_G475_K0.6400.66
474_R531_Y0.6390.66
394_L404_T0.6390.66
263_H352_Y0.6390.66
375_D449_R0.6370.66
590_G593_R0.6370.66
578_G633_L0.6360.65
259_S352_Y0.6360.65
429_L486_I0.6360.65
415_K520_M0.6350.65
511_E515_K0.6350.65
758_G764_Q0.6350.65
549_E605_T0.6340.65
270_I283_A0.6340.65
454_E496_S0.6330.65
599_I612_G0.6330.65
418_N496_S0.6330.65
448_A513_M0.6330.65
641_A671_V0.6320.65
289_S331_G0.6310.65
600_G614_W0.6310.65
393_V404_T0.6300.65
415_K528_K0.6300.65
281_N323_D0.6290.65
506_G511_E0.6290.65
440_V472_L0.6280.65
559_D617_D0.6270.64
710_S725_S0.6250.64
262_V266_D0.6250.64
193_T200_F0.6240.64
344_V347_E0.6240.64
640_S672_T0.6230.64
423_H451_G0.6230.64
251_K254_E0.6220.64
266_D355_C0.6210.64
498_G519_A0.6210.64
267_A283_A0.6210.64
335_L359_T0.6210.64
323_D361_Q0.6210.64
637_I695_I0.6200.64
581_A619_A0.6190.63
386_A406_V0.6190.63
257_F266_D0.6180.63
412_N517_D0.6170.63
407_F457_I0.6170.63
159_I162_D0.6160.63
281_N287_M0.6160.63
320_M339_L0.6160.63
608_I612_G0.6160.63
624_R627_H0.6150.63
145_S148_I0.6150.63
413_R604_E0.6140.63
414_F426_G0.6130.63
580_E777_Q0.6120.63
744_I748_H0.6120.63
334_H358_M0.6120.63
441_V457_I0.6110.62
570_S774_D0.6110.62
144_V149_A0.6100.62
405_V499_I0.6100.62
579_A635_V0.6090.62
630_G666_L0.6090.62
191_H195_M0.6090.62
253_N258_Q0.6080.62
449_R452_G0.6060.62
247_S250_I0.6040.62
566_Q582_L0.6040.62
551_V585_L0.6030.61
428_Q432_F0.6030.61
609_I646_S0.6030.61
426_G521_Y0.6030.61
371_M568_Q0.6010.61
473_A531_Y0.6010.61
415_K451_G0.6000.61
267_A278_I0.6000.61
668_E775_H0.6000.61
145_S152_A0.6000.61
353_V356_K0.5980.61
290_K335_L0.5980.61
386_A450_L0.5970.61
728_D764_Q0.5950.60
261_I352_Y0.5950.60
713_K739_I0.5950.60
216_F228_C0.5940.60
744_I768_L0.5930.60
285_E292_G0.5930.60
271_L277_I0.5920.60
343_E348_L0.5910.60
281_N352_Y0.5910.60
260_L354_I0.5910.60
199_T203_D0.5910.60
670_E700_D0.5900.60
472_L475_K0.5900.60
187_I195_M0.5880.59
249_R252_D0.5880.59
721_K777_Q0.5870.59
442_P462_A0.5860.59
151_A158_K0.5860.59
608_I643_Q0.5850.59
410_D419_D0.5840.59
418_N427_D0.5830.59
383_R423_H0.5820.59
306_V314_K0.5820.59
143_T146_I0.5810.59
638_N701_D0.5810.59
477_I529_S0.5810.59
594_P597_E0.5800.58
526_R530_K0.5800.58
149_A157_L0.5790.58
484_F493_T0.5780.58
148_I152_A0.5770.58
412_N527_N0.5770.58
463_N468_E0.5770.58
186_G198_A0.5770.58
662_L695_I0.5760.58
281_N284_G0.5760.58
762_A765_K0.5750.58
583_I592_L0.5730.58
682_H686_V0.5720.57
585_L773_C0.5720.57
524_K528_K0.5720.57
418_N451_G0.5720.57
708_S760_E0.5710.57
397_E503_P0.5700.57
328_T335_L0.5700.57
394_L506_G0.5690.57
759_V768_L0.5690.57
671_V746_M0.5690.57
279_S282_H0.5690.57
745_A749_Q0.5690.57
522_A538_I0.5690.57
518_M542_E0.5680.57
305_K309_L0.5680.57
764_Q780_F0.5680.57
586_V590_G0.5670.57
425_V486_I0.5670.57
234_L237_S0.5670.57
566_Q721_K0.5670.57
584_R670_E0.5660.57
317_K320_M0.5650.56
219_S228_C0.5650.56
704_T709_L0.5640.56
553_R607_L0.5640.56
305_K310_F0.5640.56
410_D451_G0.5640.56
399_S445_G0.5630.56
348_L352_Y0.5630.56
782_S793_F0.5630.56
392_K442_P0.5630.56
247_S251_K0.5620.56
766_Q769_F0.5620.56
730_I768_L0.5620.56
414_F517_D0.5620.56
566_Q584_R0.5620.56
235_F239_A0.5610.56
711_Y726_F0.5600.56
721_K779_F0.5600.56
657_L667_L0.5600.56
426_G496_S0.5590.56
423_H496_S0.5590.56
677_M680_L0.5590.56
496_S520_M0.5590.56
370_R373_H0.5580.56
236_S240_D0.5580.56
676_T706_H0.5580.56
470_D499_I0.5570.55
705_G726_F0.5570.55
505_D515_K0.5560.55
672_T711_Y0.5550.55
418_N517_D0.5550.55
144_V162_D0.5540.55
579_A633_L0.5540.55
606_G667_L0.5530.55
365_E368_I0.5520.55
505_D512_L0.5510.55
453_D528_K0.5510.55
688_S716_P0.5510.55
580_E670_E0.5510.55
152_A164_A0.5510.55
395_N399_S0.5500.54
582_L757_E0.5490.54
412_N415_K0.5490.54
260_L356_K0.5480.54
755_I775_H0.5480.54
377_L427_D0.5480.54
566_Q638_N0.5480.54
403_N504_K0.5480.54
265_I352_Y0.5480.54
673_E700_D0.5480.54
388_S392_K0.5470.54
257_F352_Y0.5470.54
268_I285_E0.5470.54
421_L546_L0.5460.54
322_S325_D0.5460.54
379_D431_Q0.5460.54
520_M668_E0.5460.54
150_I154_F0.5460.54
580_E673_E0.5460.54
425_V428_Q0.5450.54
680_L715_F0.5450.54
373_H388_S0.5450.54
700_D721_K0.5440.54
424_N520_M0.5440.54
790_F793_F0.5440.54
383_R454_E0.5440.54
583_I643_Q0.5440.54
779_F782_S0.5430.54
520_M524_K0.5430.54
225_I230_Q0.5430.54
492_V553_R0.5420.53
706_H711_Y0.5410.53
605_T642_R0.5400.53
410_D427_D0.5390.53
280_S288_I0.5390.53
153_S156_S0.5380.53
257_F265_I0.5380.53
266_D283_A0.5370.53
417_I491_L0.5370.53
260_L279_S0.5370.53
642_R781_F0.5370.53
672_T707_S0.5370.53
310_F314_K0.5350.52
642_R675_M0.5350.52
720_L743_I0.5350.52
426_G454_E0.5350.52
265_I355_C0.5340.52
192_Y196_L0.5340.52
705_G708_S0.5340.52
707_S711_Y0.5340.52
219_S225_I0.5320.52
210_H223_T0.5320.52
418_N423_H0.5320.52
561_F607_L0.5310.52
372_A410_D0.5310.52
414_F419_D0.5310.52
339_L752_L0.5310.52
298_W302_T0.5310.52
723_D757_E0.5300.52
414_F452_G0.5300.52
389_H460_T0.5300.52
445_G460_T0.5300.52
266_D354_I0.5290.52
737_E741_G0.5280.52
515_K539_G0.5270.51
413_R534_Y0.5260.51
721_K760_E0.5260.51
414_F423_H0.5260.51
603_E674_S0.5260.51
430_L453_D0.5260.51
539_G790_F0.5250.51
414_F454_E0.5240.51
585_L598_F0.5240.51
214_Q218_W0.5230.51
579_A623_A0.5230.51
709_L758_G0.5230.51
189_G201_H0.5220.51
539_G543_T0.5220.51
148_I153_S0.5210.51
711_Y714_D0.5210.51
412_N494_S0.5200.50
518_M538_I0.5200.50
427_D524_K0.5190.50
612_G704_T0.5190.50
554_E557_E0.5190.50
153_S164_A0.5190.50
350_S353_V0.5190.50
599_I640_S0.5180.50
145_S157_L0.5170.50
260_L268_I0.5170.50
383_R451_G0.5170.50
156_S162_D0.5170.50
172_L177_G0.5160.50
582_L700_D0.5150.50
346_Q349_D0.5150.50
556_I709_L0.5140.50
269_F280_S0.5130.50
172_L176_K0.5120.49
408_F415_K0.5120.49
154_F161_F0.5110.49
624_R660_Y0.5100.49
213_V223_T0.5100.49
253_N257_F0.5100.49
153_S159_I0.5100.49
552_L601_V0.5100.49
261_I283_A0.5090.49
610_D727_I0.5090.49
368_I373_H0.5080.49
218_W230_Q0.5080.49
255_Q259_S0.5080.49
270_I279_S0.5080.49
566_Q670_E0.5070.49
152_A159_I0.5070.49
266_D271_L0.5070.49
705_G757_E0.5070.49
380_L434_A0.5070.49
451_G524_K0.5060.49
388_S391_T0.5060.49
171_H181_I0.5060.49
419_D451_G0.5050.48
266_D334_H0.5030.48
187_I200_F0.5030.48
179_S190_M0.5020.48
410_D452_G0.5010.48
708_S757_E0.5010.48
641_A644_F0.5000.48
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rnhA 2 0.5225 100 0.398 Contact Map
4j40A 2 0.3137 100 0.404 Contact Map
3pjxA 1 0.5225 100 0.425 Contact Map
3gfzA 2 0.4738 100 0.497 Contact Map
4hjfA 1 0.3237 100 0.532 Contact Map
4hu4A 1 0.3063 100 0.607 Contact Map
4kieA 1 0.325 100 0.608 Contact Map
3sy8A 6 0.4925 100 0.609 Contact Map
2r6oA 2 0.32 100 0.611 Contact Map
4rniA 2 0.3162 100 0.615 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0171 seconds.