PPS - BACSU - GREMLIN Contacts

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PPS - Putative phosphoenolpyruvate synthase

UniProt:	O34309	Sequences: MSSLVLGLHEIEKTQLSLVGGKGLHLGELSKIQGIQVPEGFCVTTVGYQKAIEQNETLQVLLDQLTMLKVEDRDQIGNISRKIRQIIMEVDIPSDVVKAVAQYLSQFGEEHAYAVRSSATAEDLPHASFAGQQDTYLNITGVDAILQHISKCWASLFTDRAVIYRMQNGFDHSQVYLSVIVQRMVFPQASGILFTADPITSNRKVLSIDAGFGLGEALVSGLVSADCFKVQDGQIIDKRIATKKMAIYGRKEGGTETQQIDSDQQKAQTLTDEQILQLARIGRQIEAHFGQPQDIEWCLARDTFYIVQSRPITTLFPIPEASDQENHVYISVGHQQMMTDPIKPLGLSFFLLTTVAPMRKAGGRLFVDVTHHLASPDSREVFLKGMGQHDQLLKDALMTIIKRRDFIKSIPNDKTAPNPSRGNADMPAQVENDPTIVSDLIESSQTSIEELKQNIQTKSGSDLFRFILEDIQELKKILFNPKSSVLIRTAMNASLWINEKMNEWLGEKNAADTLSQSVPHNITSEMGLALLDVADVIRPYPEVIDYLQHVKDDNFLDELAKFDGGSKTRDAIYDYLSKYGMRCTGEIDITRTRWSEKPTTLVPMILNNIKNFEPNVGHRKFEQGRQEALKKEQELLDRLKQLPDGEQKAKETKRAIDIIRNFSGFREYPKYGMVNRYFVYKQALLKEAEQLIEAGVIHEKEDIYYLTFEELHEVVRTHKLDYQIISTRKDEYTLYEKLSPPRVITSDGEIVTGEYKRENLPAGAIVGLPVSSGVIEGRARVILNMEDADLEDGDILVTSFTDPSWTPLFVSIKGLVTEVGGLMTHGAVIAREYGLPAVVGVENAAKLIKDGQRIRVHGTEGYIEIF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	866 (810)
Sequences:	997 (751)
Seq/√Len:	26.4

BACSU - PPS YVKC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
779_A	848_I	9.982	1.00
197_D	205_V	9.401	1.00
285_I	306_I	8.874	1.00
776_E	855_R	8.684	1.00
814_G	856_V	6.713	1.00
298_C	307_V	5.981	1.00
795_I	814_G	5.958	1.00
779_A	854_I	5.488	1.00
193_L	282_G	5.263	1.00
344_P	705_Y	5.090	1.00
776_E	853_R	4.963	1.00
281_I	306_I	4.609	1.00
838_V	856_V	4.365	1.00
710_E	728_R	4.318	1.00
23_G	180_I	4.312	1.00
28_E	288_H	4.067	1.00
299_L	304_F	3.862	1.00
285_I	295_I	3.848	1.00
209_D	227_C	3.806	1.00
114_A	137_L	3.777	1.00
230_V	275_I	3.679	1.00
238_K	272_D	3.662	1.00
271_T	274_Q	3.587	1.00
193_L	278_L	3.531	1.00
104_L	113_Y	3.508	1.00
848_I	854_I	3.340	1.00
189_A	269_T	3.327	1.00
187_P	298_C	3.323	1.00
210_A	269_T	3.303	1.00
195_T	282_G	3.179	1.00
778_R	853_R	3.149	1.00
698_H	722_Y	3.133	1.00
857_H	860_E	3.108	1.00
459_S	462_D	3.107	1.00
293_Q	309_S	2.974	1.00
50_K	95_D	2.937	1.00
818_E	841_V	2.917	1.00
855_R	864_E	2.889	1.00
188_Q	300_A	2.835	1.00
703_I	711_L	2.823	1.00
794_D	850_D	2.799	1.00
780_R	794_D	2.721	0.99
774_V	855_R	2.688	0.99
211_G	218_L	2.675	0.99
289_F	309_S	2.662	0.99
24_L	28_E	2.649	0.99
193_L	206_L	2.577	0.99
784_N	787_D	2.557	0.99
211_G	217_A	2.547	0.99
689_E	700_K	2.532	0.99
838_V	863_I	2.497	0.99
138_N	214_L	2.495	0.99
779_A	816_V	2.460	0.99
39_E	183_R	2.445	0.99
19_V	42_C	2.429	0.99
208_I	275_I	2.395	0.99
212_F	243_K	2.371	0.99
686_K	690_Q	2.304	0.98
43_V	100_V	2.264	0.98
793_G	813_K	2.260	0.98
196_A	312_I	2.257	0.98
196_A	203_R	2.239	0.98
775_I	814_G	2.227	0.98
55_N	90_V	2.218	0.98
185_V	298_C	2.178	0.97
379_R	382_F	2.168	0.97
92_I	146_L	2.146	0.97
41_F	181_V	2.125	0.97
161_A	165_R	2.124	0.97
808_L	812_I	2.111	0.97
232_D	286_E	2.098	0.97
354_T	673_M	2.035	0.96
815_L	826_G	2.017	0.96
81_R	85_Q	2.015	0.96
533_V	568_T	1.993	0.96
85_Q	89_E	1.979	0.95
812_I	815_L	1.964	0.95
363_G	366_F	1.956	0.95
781_V	850_D	1.950	0.95
490_A	493_A	1.923	0.95
107_F	113_Y	1.917	0.94
80_S	162_V	1.902	0.94
148_H	151_K	1.894	0.94
115_V	139_I	1.882	0.94
551_K	554_N	1.878	0.94
579_Y	671_Y	1.867	0.94
192_I	211_G	1.857	0.93
366_F	370_T	1.856	0.93
814_G	848_I	1.850	0.93
586_E	670_K	1.843	0.93
279_A	704_Y	1.834	0.93
282_G	295_I	1.825	0.93
798_T	812_I	1.823	0.93
778_R	794_D	1.821	0.93
285_I	309_S	1.792	0.92
588_D	821_G	1.784	0.92
141_G	144_A	1.781	0.92
849_K	852_Q	1.763	0.92
537_I	568_T	1.761	0.91
342_I	347_L	1.760	0.91
33_Q	36_Q	1.750	0.91
48_Y	157_F	1.749	0.91
22_K	26_L	1.733	0.91
50_K	55_N	1.718	0.90
196_A	315_L	1.717	0.90
96_V	101_A	1.716	0.90
705_Y	729_K	1.701	0.90
117_S	128_S	1.693	0.90
104_L	107_F	1.693	0.90
545_D	549_H	1.688	0.90
588_D	826_G	1.687	0.90
120_T	175_V	1.681	0.89
523_T	526_M	1.681	0.89
268_Q	275_I	1.679	0.89
468_L	712_H	1.665	0.89
135_T	312_I	1.665	0.89
586_E	839_V	1.660	0.89
427_P	431_E	1.657	0.89
838_V	858_G	1.653	0.89
20_G	26_L	1.643	0.88
778_R	795_I	1.638	0.88
301_R	701_E	1.618	0.88
216_E	220_S	1.617	0.87
225_A	821_G	1.609	0.87
774_V	857_H	1.607	0.87
246_A	260_I	1.592	0.87
136_Y	151_K	1.589	0.87
132_Q	829_I	1.587	0.86
816_V	854_I	1.577	0.86
228_F	275_I	1.576	0.86
363_G	368_D	1.574	0.86
851_G	861_G	1.565	0.86
226_D	243_K	1.564	0.86
346_G	523_T	1.562	0.86
96_V	99_A	1.552	0.85
670_K	674_V	1.547	0.85
546_Y	550_V	1.545	0.85
841_V	863_I	1.543	0.85
346_G	588_D	1.543	0.85
136_Y	148_H	1.517	0.84
386_M	389_H	1.515	0.84
277_Q	302_D	1.508	0.83
21_G	26_L	1.502	0.83
121_A	124_L	1.495	0.83
670_K	839_V	1.489	0.83
404_R	407_I	1.483	0.82
49_Q	176_Y	1.481	0.82
670_K	802_D	1.476	0.82
94_S	97_V	1.469	0.82
525_E	529_A	1.468	0.82
46_V	49_Q	1.465	0.82
100_V	105_S	1.458	0.81
138_N	249_G	1.455	0.81
133_Q	161_A	1.449	0.81
816_V	863_I	1.447	0.81
198_P	831_R	1.441	0.81
795_I	854_I	1.439	0.80
124_L	133_Q	1.429	0.80
670_K	803_P	1.429	0.80
816_V	848_I	1.425	0.80
137_L	214_L	1.419	0.80
663_S	814_G	1.408	0.79
134_D	160_R	1.405	0.79
277_Q	303_T	1.391	0.78
582_R	586_E	1.382	0.78
776_E	864_E	1.375	0.77
281_I	285_I	1.366	0.77
626_Q	630_K	1.359	0.76
247_I	257_T	1.359	0.76
824_T	827_A	1.355	0.76
785_M	812_I	1.352	0.76
816_V	856_V	1.349	0.76
190_S	298_C	1.347	0.76
191_G	832_E	1.345	0.76
596_E	685_L	1.344	0.76
285_I	289_F	1.338	0.75
211_G	247_I	1.337	0.75
424_A	589_I	1.329	0.75
23_G	30_S	1.328	0.75
586_E	593_R	1.326	0.75
362_G	366_F	1.326	0.75
225_A	228_F	1.325	0.75
261_D	264_Q	1.325	0.75
594_W	821_G	1.323	0.74
706_L	728_R	1.310	0.74
22_K	38_P	1.308	0.74
60_V	92_I	1.306	0.73
543_V	568_T	1.303	0.73
60_V	94_S	1.299	0.73
575_Y	594_W	1.299	0.73
272_D	312_I	1.299	0.73
54_Q	94_S	1.296	0.73
775_I	848_I	1.294	0.73
582_R	839_V	1.284	0.72
51_A	90_V	1.283	0.72
336_Q	346_G	1.283	0.72
144_A	147_Q	1.281	0.72
824_T	828_V	1.281	0.72
128_S	832_E	1.275	0.72
190_S	266_K	1.265	0.71
331_S	334_H	1.265	0.71
23_G	26_L	1.265	0.71
147_Q	151_K	1.260	0.71
588_D	670_K	1.258	0.71
692_I	700_K	1.258	0.71
579_Y	808_L	1.255	0.70
384_K	389_H	1.252	0.70
230_V	279_A	1.250	0.70
99_A	729_K	1.247	0.70
351_L	355_V	1.246	0.70
632_E	653_K	1.246	0.70
671_Y	803_P	1.237	0.69
218_L	225_A	1.233	0.69
28_E	31_K	1.233	0.69
529_A	578_K	1.232	0.69
779_A	796_L	1.232	0.69
20_G	38_P	1.229	0.69
186_F	865_I	1.229	0.69
295_I	306_I	1.228	0.69
338_M	824_T	1.221	0.68
773_G	861_G	1.220	0.68
54_Q	86_I	1.217	0.68
238_K	268_Q	1.211	0.68
226_D	270_L	1.211	0.68
235_I	275_I	1.210	0.68
329_Y	526_M	1.210	0.68
334_H	587_I	1.209	0.67
670_K	770_V	1.209	0.67
252_E	258_Q	1.208	0.67
713_E	717_T	1.207	0.67
831_R	861_G	1.204	0.67
843_N	847_L	1.204	0.67
181_V	781_V	1.203	0.67
108_G	141_G	1.196	0.67
195_T	278_L	1.191	0.66
563_D	567_K	1.191	0.66
818_E	843_N	1.178	0.65
405_D	410_I	1.177	0.65
60_V	252_E	1.174	0.65
337_M	587_I	1.174	0.65
23_G	42_C	1.170	0.65
111_H	183_R	1.168	0.65
19_V	89_E	1.166	0.65
333_G	667_E	1.163	0.64
801_T	805_W	1.158	0.64
501_M	505_L	1.156	0.64
87_I	697_I	1.155	0.64
31_K	52_I	1.151	0.64
132_Q	315_L	1.149	0.63
688_A	701_E	1.147	0.63
727_T	731_E	1.147	0.63
99_A	102_Q	1.144	0.63
553_D	783_L	1.143	0.63
59_Q	94_S	1.141	0.63
359_R	368_D	1.140	0.63
780_R	791_E	1.136	0.63
807_P	829_I	1.131	0.62
22_K	37_V	1.129	0.62
780_R	850_D	1.126	0.62
586_E	667_E	1.126	0.62
461_S	578_K	1.124	0.62
117_S	191_G	1.123	0.62
825_H	832_E	1.120	0.61
91_D	269_T	1.120	0.61
625_R	629_L	1.120	0.61
177_L	814_G	1.119	0.61
525_E	528_L	1.118	0.61
331_S	336_Q	1.115	0.61
802_D	818_E	1.113	0.61
330_I	386_M	1.112	0.61
330_I	393_L	1.110	0.61
43_V	99_A	1.109	0.61
542_E	693_E	1.108	0.61
526_M	828_V	1.107	0.61
342_I	354_T	1.107	0.61
19_V	44_T	1.101	0.60
806_T	812_I	1.101	0.60
83_I	86_I	1.099	0.60
90_V	241_A	1.095	0.60
198_P	576_L	1.093	0.60
165_R	293_Q	1.091	0.59
36_Q	50_K	1.090	0.59
346_G	590_T	1.087	0.59
100_V	695_G	1.086	0.59
802_D	839_V	1.086	0.59
542_E	774_V	1.085	0.59
336_Q	824_T	1.084	0.59
351_L	356_A	1.079	0.58
804_S	814_G	1.079	0.58
805_W	861_G	1.077	0.58
20_G	23_G	1.077	0.58
333_G	670_K	1.074	0.58
406_F	411_P	1.073	0.58
337_M	588_D	1.068	0.58
24_L	27_G	1.066	0.58
733_T	736_E	1.063	0.57
370_T	519_P	1.062	0.57
119_A	133_Q	1.060	0.57
779_A	797_V	1.059	0.57
339_T	346_G	1.056	0.57
83_I	89_E	1.056	0.57
104_L	108_G	1.052	0.57
341_P	590_T	1.051	0.56
50_K	96_V	1.050	0.56
523_T	671_Y	1.048	0.56
19_V	27_G	1.044	0.56
235_I	238_K	1.044	0.56
86_I	693_E	1.043	0.56
568_T	572_I	1.042	0.56
20_G	37_V	1.040	0.56
50_K	82_K	1.038	0.56
101_A	145_I	1.035	0.55
22_K	29_L	1.034	0.55
821_G	826_G	1.034	0.55
121_A	133_Q	1.032	0.55
195_T	206_L	1.030	0.55
809_F	832_E	1.030	0.55
191_G	221_G	1.029	0.55
247_I	255_T	1.028	0.55
278_L	285_I	1.027	0.55
767_G	861_G	1.027	0.55
169_G	834_G	1.025	0.55
804_S	818_E	1.022	0.54
407_I	411_P	1.021	0.54
112_A	140_T	1.019	0.54
43_V	96_V	1.019	0.54
92_I	96_V	1.017	0.54
49_Q	52_I	1.017	0.54
779_A	814_G	1.017	0.54
349_F	448_I	1.014	0.54
183_R	697_I	1.013	0.54
128_S	802_D	1.010	0.53
800_F	817_T	1.009	0.53
364_R	368_D	1.006	0.53
347_L	354_T	1.005	0.53
858_G	861_G	1.004	0.53
278_L	304_F	1.003	0.53
119_A	156_L	1.003	0.53
336_Q	339_T	1.001	0.53
39_E	59_Q	0.999	0.53
667_E	670_K	0.996	0.52
775_I	795_I	0.994	0.52
54_Q	88_M	0.994	0.52
135_T	766_V	0.990	0.52
343_K	590_T	0.990	0.52
442_E	445_Q	0.990	0.52
219_V	801_T	0.988	0.52
119_A	315_L	0.988	0.52
785_M	798_T	0.987	0.52
51_A	60_V	0.986	0.52
181_V	758_E	0.986	0.52
691_L	696_V	0.984	0.52
248_Y	258_Q	0.983	0.51
351_L	354_T	0.983	0.51
121_A	196_A	0.982	0.51
790_L	794_D	0.982	0.51
215_G	219_V	0.981	0.51
190_S	400_I	0.980	0.51
172_H	195_T	0.978	0.51
765_I	841_V	0.977	0.51
452_K	467_I	0.977	0.51
202_N	835_L	0.976	0.51
797_V	848_I	0.974	0.51
689_E	693_E	0.974	0.51
26_L	38_P	0.971	0.51
128_S	191_G	0.971	0.51
522_I	526_M	0.971	0.51
135_T	307_V	0.970	0.50
807_P	826_G	0.968	0.50
180_I	184_M	0.966	0.50
123_D	130_A	0.965	0.50
342_I	673_M	0.965	0.50
136_Y	711_L	0.964	0.50
274_Q	299_L	0.963	0.50
104_L	145_I	0.957	0.49
53_E	60_V	0.956	0.49
123_D	131_G	0.956	0.49
246_A	264_Q	0.955	0.49
781_V	785_M	0.955	0.49
594_W	827_A	0.955	0.49
135_T	247_I	0.953	0.49
526_M	670_K	0.951	0.49
20_G	29_L	0.951	0.49
124_L	170_F	0.949	0.49
521_N	526_M	0.948	0.49
49_Q	54_Q	0.948	0.49
586_E	674_V	0.947	0.49
550_V	558_E	0.945	0.49
135_T	304_F	0.941	0.48
97_V	101_A	0.939	0.48
684_L	708_F	0.938	0.48
348_S	707_T	0.936	0.48
443_S	446_T	0.935	0.48
277_Q	304_F	0.934	0.48
243_K	265_Q	0.933	0.48
181_V	421_R	0.933	0.48
51_A	93_P	0.933	0.48
122_E	130_A	0.931	0.48
120_T	124_L	0.929	0.47
662_F	671_Y	0.928	0.47
527_G	531_L	0.927	0.47
55_N	87_I	0.925	0.47
818_E	842_E	0.925	0.47
555_F	606_L	0.924	0.47
47_G	96_V	0.923	0.47
187_P	215_G	0.923	0.47
122_E	131_G	0.922	0.47
89_E	94_S	0.922	0.47
681_K	685_L	0.922	0.47
355_V	673_M	0.920	0.47
178_S	192_I	0.919	0.47
154_A	312_I	0.917	0.47
526_M	587_I	0.912	0.46
51_A	257_T	0.911	0.46
673_M	821_G	0.910	0.46
688_A	692_I	0.908	0.46
537_I	609_I	0.907	0.46
824_T	840_G	0.907	0.46
80_S	159_D	0.906	0.46
699_E	787_D	0.905	0.46
670_K	823_M	0.904	0.46
697_I	814_G	0.904	0.46
300_A	305_Y	0.902	0.45
587_I	677_Y	0.902	0.45
773_G	805_W	0.900	0.45
213_G	773_G	0.900	0.45
337_M	354_T	0.899	0.45
111_H	181_V	0.898	0.45
521_N	587_I	0.897	0.45
197_D	297_W	0.896	0.45
126_H	285_I	0.896	0.45
133_Q	165_R	0.895	0.45
831_R	851_G	0.895	0.45
169_G	303_T	0.895	0.45
114_A	185_V	0.895	0.45
333_G	586_E	0.895	0.45
583_C	670_K	0.893	0.45
196_A	200_T	0.892	0.45
333_G	338_M	0.892	0.45
588_D	593_R	0.891	0.45
796_L	834_G	0.888	0.44
628_A	632_E	0.888	0.44
143_D	146_L	0.888	0.44
51_A	89_E	0.886	0.44
330_I	369_V	0.886	0.44
235_I	241_A	0.884	0.44
303_T	814_G	0.884	0.44
278_L	282_G	0.884	0.44
221_G	832_E	0.884	0.44
137_L	216_E	0.884	0.44
466_F	469_E	0.883	0.44
138_N	216_E	0.879	0.44
535_D	601_L	0.878	0.44
210_A	226_D	0.877	0.44
129_F	215_G	0.877	0.44
378_S	382_F	0.877	0.44
86_I	96_V	0.876	0.44
52_I	82_K	0.875	0.43
448_I	714_V	0.872	0.43
135_T	331_S	0.872	0.43
702_D	803_P	0.871	0.43
88_M	151_K	0.871	0.43
152_C	806_T	0.871	0.43
333_G	336_Q	0.869	0.43
354_T	678_F	0.868	0.43
496_W	651_E	0.866	0.43
36_Q	89_E	0.866	0.43
197_D	229_K	0.865	0.43
241_A	247_I	0.864	0.43
53_E	59_Q	0.863	0.43
191_G	297_W	0.863	0.43
526_M	806_T	0.862	0.42
814_G	854_I	0.861	0.42
334_H	338_M	0.860	0.42
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228_F	269_T	0.857	0.42
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47_G	88_M	0.855	0.42
39_E	89_E	0.855	0.42
726_S	730_D	0.853	0.42
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338_M	770_V	0.852	0.42
228_F	268_Q	0.852	0.42
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515_S	824_T	0.850	0.42
373_L	821_G	0.850	0.42
343_K	564_G	0.850	0.42
769_P	865_I	0.849	0.42
139_I	177_L	0.848	0.41
124_L	806_T	0.848	0.41
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631_K	634_E	0.844	0.41
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275_I	279_A	0.841	0.41
41_F	103_Y	0.841	0.41
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795_I	806_T	0.837	0.41
437_V	440_L	0.835	0.41
587_I	674_V	0.834	0.40
732_Y	735_Y	0.834	0.40
144_A	426_M	0.834	0.40
236_I	239_R	0.834	0.40
168_N	729_K	0.834	0.40
383_L	386_M	0.833	0.40
26_L	117_S	0.833	0.40
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437_V	534_A	0.831	0.40
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164_Y	801_T	0.829	0.40
101_A	142_V	0.829	0.40
685_L	700_K	0.828	0.40
52_I	239_R	0.828	0.40
588_D	665_F	0.828	0.40
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138_N	192_I	0.826	0.40
237_D	247_I	0.826	0.40
100_V	443_S	0.823	0.40
152_C	691_L	0.823	0.40
218_L	824_T	0.823	0.40
59_Q	102_Q	0.823	0.40
329_Y	670_K	0.823	0.40
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207_S	229_K	0.820	0.39
277_Q	299_L	0.820	0.39
29_L	311_P	0.816	0.39
189_A	274_Q	0.814	0.39
323_D	327_H	0.814	0.39
195_T	667_E	0.814	0.39
463_L	504_W	0.811	0.39
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240_I	243_K	0.811	0.39
670_K	804_S	0.810	0.39
40_G	826_G	0.809	0.39
288_H	506_G	0.808	0.39
286_E	292_P	0.808	0.39
498_N	605_I	0.807	0.39
117_S	832_E	0.807	0.39
292_P	797_V	0.805	0.38
181_V	303_T	0.805	0.38
157_F	165_R	0.804	0.38
306_I	606_L	0.804	0.38
286_E	314_T	0.803	0.38
350_F	587_I	0.803	0.38
261_D	265_Q	0.801	0.38
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275_I	535_D	0.799	0.38
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192_I	218_L	0.799	0.38
285_I	358_M	0.797	0.38
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252_E	256_E	0.796	0.38
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313_T	831_R	0.794	0.38
577_S	711_L	0.794	0.38
449_E	577_S	0.794	0.38
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629_L	633_Q	0.791	0.37
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647_Q	651_E	0.786	0.37
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193_L	281_I	0.777	0.36
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583_C	802_D	0.770	0.36
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128_S	666_R	0.749	0.35
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201_S	613_E	0.749	0.35
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246_A	258_Q	0.746	0.34
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537_I	543_V	0.738	0.34
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248_Y	725_I	0.732	0.33
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342_I	826_G	0.730	0.33
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80_S	83_I	0.721	0.33
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559_L	683_A	0.718	0.32
313_T	856_V	0.718	0.32
822_L	827_A	0.717	0.32
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382_F	393_L	0.702	0.31
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581_M	821_G	0.691	0.31
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384_K	388_Q	0.690	0.31
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667_E	829_I	0.686	0.30
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664_G	670_K	0.686	0.30
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36_Q	48_Y	0.609	0.26
547_L	782_I	0.608	0.26
176_Y	238_K	0.608	0.26
87_I	239_R	0.607	0.26
132_Q	209_D	0.606	0.26
297_W	807_P	0.606	0.26
225_A	833_Y	0.606	0.26
171_D	288_H	0.603	0.25
522_I	525_E	0.603	0.25
39_E	43_V	0.603	0.25
289_F	855_R	0.602	0.25
478_L	769_P	0.602	0.25
770_V	839_V	0.602	0.25
158_T	172_H	0.602	0.25
583_C	593_R	0.601	0.25
568_T	576_L	0.600	0.25
168_N	604_M	0.600	0.25
81_R	89_E	0.600	0.25
581_M	588_D	0.600	0.25
691_L	806_T	0.599	0.25
110_E	301_R	0.599	0.25
338_M	670_K	0.599	0.25
50_K	102_Q	0.599	0.25
331_S	823_M	0.599	0.25
256_E	263_D	0.599	0.25
359_R	366_F	0.599	0.25
183_R	309_S	0.598	0.25
105_S	142_V	0.597	0.25
523_T	575_Y	0.597	0.25
434_P	671_Y	0.596	0.25
113_Y	149_I	0.596	0.25
828_V	835_L	0.596	0.25
773_G	797_V	0.595	0.25
777_G	795_I	0.594	0.25
48_Y	568_T	0.593	0.25
346_G	526_M	0.593	0.25
297_W	313_T	0.592	0.25
554_N	558_E	0.592	0.25
332_V	338_M	0.591	0.25
181_V	542_E	0.590	0.25
42_C	50_K	0.590	0.25
673_M	678_F	0.589	0.25
750_I	803_P	0.589	0.25
144_A	469_E	0.589	0.25
518_V	523_T	0.589	0.25
198_P	830_A	0.588	0.25
170_F	180_I	0.588	0.25
281_I	304_F	0.588	0.25
817_T	841_V	0.588	0.25
294_D	310_R	0.587	0.25
92_I	703_I	0.587	0.25
672_G	675_N	0.586	0.25
767_G	773_G	0.586	0.25
94_S	102_Q	0.585	0.24
143_D	597_K	0.585	0.24
185_V	290_G	0.585	0.24
40_G	821_G	0.584	0.24
648_K	778_R	0.584	0.24
27_G	48_Y	0.584	0.24
342_I	678_F	0.583	0.24
177_L	208_I	0.583	0.24
48_Y	120_T	0.583	0.24
342_I	350_F	0.583	0.24
186_F	300_A	0.582	0.24
267_A	542_E	0.582	0.24
333_G	770_V	0.582	0.24
820_G	825_H	0.582	0.24
239_R	261_D	0.581	0.24
116_R	123_D	0.581	0.24
449_E	699_E	0.580	0.24
520_H	526_M	0.580	0.24
350_F	353_T	0.580	0.24
341_P	732_Y	0.579	0.24
342_I	821_G	0.579	0.24
201_S	812_I	0.578	0.24
817_T	850_D	0.578	0.24
118_S	830_A	0.578	0.24
627_E	634_E	0.577	0.24
59_Q	97_V	0.576	0.24
527_G	821_G	0.576	0.24
198_P	773_G	0.576	0.24
220_S	821_G	0.575	0.24
312_I	561_K	0.575	0.24
19_V	43_V	0.574	0.24
467_I	474_L	0.574	0.24
670_K	809_F	0.574	0.24
279_A	659_I	0.574	0.24
575_Y	670_K	0.574	0.24
170_F	175_V	0.573	0.24
841_V	844_A	0.573	0.24
808_L	815_L	0.572	0.24
476_K	840_G	0.572	0.24
557_D	630_K	0.571	0.24
108_G	183_R	0.571	0.24
334_H	337_M	0.571	0.24
542_E	545_D	0.570	0.24
588_D	818_E	0.570	0.24
632_E	636_L	0.570	0.24
836_P	861_G	0.570	0.24
252_E	259_Q	0.570	0.24
667_E	803_P	0.570	0.24
458_K	637_D	0.570	0.24
98_K	183_R	0.569	0.24
104_L	157_F	0.569	0.24
40_G	809_F	0.569	0.24
200_T	232_D	0.568	0.24
55_N	89_E	0.568	0.24
775_I	789_D	0.568	0.24
799_S	830_A	0.567	0.23
595_S	678_F	0.565	0.23
113_Y	548_Q	0.565	0.23
21_G	30_S	0.565	0.23
581_M	824_T	0.564	0.23
153_W	179_V	0.564	0.23
197_D	277_Q	0.562	0.23
354_T	474_L	0.562	0.23
832_E	836_P	0.562	0.23
149_I	272_D	0.561	0.23
132_Q	220_S	0.561	0.23
462_D	465_R	0.560	0.23
856_V	863_I	0.560	0.23
106_Q	693_E	0.559	0.23
55_N	60_V	0.558	0.23
21_G	180_I	0.558	0.23
84_R	134_D	0.558	0.23
244_K	248_Y	0.558	0.23
314_T	839_V	0.558	0.23
270_L	780_R	0.558	0.23
507_E	828_V	0.557	0.23
518_V	821_G	0.557	0.23
35_I	295_I	0.556	0.23
430_V	529_A	0.556	0.23
35_I	39_E	0.555	0.23
202_N	205_V	0.555	0.23
31_K	89_E	0.555	0.23
114_A	214_L	0.553	0.23
728_R	861_G	0.553	0.23
585_G	803_P	0.553	0.23
94_S	428_A	0.552	0.23
295_I	792_D	0.552	0.23
616_V	711_L	0.552	0.23
687_E	711_L	0.552	0.23
133_Q	184_M	0.551	0.23
251_K	255_T	0.551	0.23
326_N	377_D	0.551	0.23
497_I	545_D	0.550	0.23
710_E	831_R	0.550	0.23
495_L	498_N	0.550	0.23
666_R	670_K	0.550	0.23
60_V	88_M	0.549	0.23
464_F	467_I	0.549	0.23
116_R	122_E	0.549	0.23
764_A	863_I	0.549	0.23
107_F	703_I	0.548	0.22
470_D	474_L	0.548	0.22
124_L	523_T	0.547	0.22
181_V	453_Q	0.547	0.22
133_Q	806_T	0.547	0.22
809_F	826_G	0.547	0.22
598_P	794_D	0.546	0.22
694_A	698_H	0.546	0.22
818_E	861_G	0.546	0.22
337_M	803_P	0.546	0.22
200_T	734_L	0.545	0.22
240_I	576_L	0.545	0.22
655_A	674_V	0.545	0.22
767_G	818_E	0.545	0.22
521_N	670_K	0.544	0.22
220_S	401_I	0.544	0.22
228_F	470_D	0.543	0.22
154_A	195_T	0.543	0.22
120_T	133_Q	0.542	0.22
448_I	451_L	0.542	0.22
136_Y	139_I	0.542	0.22
24_L	88_M	0.542	0.22
145_I	751_V	0.542	0.22
818_E	821_G	0.541	0.22
329_Y	368_D	0.541	0.22
343_K	588_D	0.540	0.22
711_L	740_P	0.540	0.22
818_E	831_R	0.540	0.22
116_R	130_A	0.539	0.22
146_L	149_I	0.539	0.22
249_G	256_E	0.539	0.22
309_S	368_D	0.538	0.22
816_V	833_Y	0.538	0.22
208_I	270_L	0.537	0.22
39_E	54_Q	0.536	0.22
583_C	770_V	0.536	0.22
801_T	829_I	0.535	0.22
366_F	821_G	0.535	0.22
209_D	628_A	0.535	0.22
224_S	537_I	0.535	0.22
197_D	725_I	0.535	0.22
28_E	60_V	0.535	0.22
240_I	245_M	0.535	0.22
577_S	725_I	0.535	0.22
581_M	826_G	0.535	0.22
770_V	821_G	0.534	0.22
348_S	775_I	0.534	0.22
686_K	714_V	0.534	0.22
323_D	605_I	0.534	0.22
336_Q	368_D	0.534	0.22
50_K	85_Q	0.533	0.22
127_A	819_V	0.533	0.22
114_A	135_T	0.533	0.22
813_K	854_I	0.533	0.22
198_P	598_P	0.533	0.22
583_C	678_F	0.532	0.22
85_Q	303_T	0.532	0.22
94_S	450_E	0.532	0.22
581_M	673_M	0.532	0.22
79_I	83_I	0.531	0.22
116_R	131_G	0.531	0.22
139_I	633_Q	0.529	0.22
128_S	839_V	0.529	0.22
434_P	438_S	0.529	0.22
129_F	806_T	0.529	0.22
521_N	527_G	0.529	0.22
610_K	791_E	0.528	0.21
380_E	384_K	0.528	0.21
596_E	682_Q	0.528	0.21
401_I	491_M	0.527	0.21
135_T	177_L	0.526	0.21
218_L	705_Y	0.526	0.21
312_I	782_I	0.525	0.21
161_A	304_F	0.525	0.21
366_F	369_V	0.525	0.21
704_Y	769_P	0.525	0.21
494_S	623_Q	0.524	0.21
59_Q	236_I	0.524	0.21
96_V	241_A	0.524	0.21
93_P	96_V	0.523	0.21
52_I	359_R	0.523	0.21
525_E	705_Y	0.523	0.21
587_I	667_E	0.523	0.21
218_L	526_M	0.522	0.21
270_L	601_L	0.522	0.21
333_G	350_F	0.522	0.21
453_Q	473_E	0.522	0.21
136_Y	465_R	0.522	0.21
575_Y	599_T	0.521	0.21
637_D	689_E	0.521	0.21
706_L	844_A	0.521	0.21
781_V	851_G	0.521	0.21
321_A	400_I	0.520	0.21
49_Q	174_Q	0.520	0.21
803_P	808_L	0.520	0.21
147_Q	150_S	0.520	0.21
344_P	725_I	0.520	0.21
571_A	574_D	0.520	0.21
265_Q	268_Q	0.519	0.21
100_V	163_I	0.519	0.21
388_Q	391_Q	0.519	0.21
577_S	595_S	0.518	0.21
346_G	823_M	0.518	0.21
59_Q	79_I	0.518	0.21
346_G	664_G	0.517	0.21
257_T	261_D	0.517	0.21
342_I	346_G	0.516	0.21
167_Q	782_I	0.516	0.21
575_Y	815_L	0.516	0.21
527_G	806_T	0.516	0.21
277_Q	657_D	0.516	0.21
129_F	156_L	0.515	0.21
190_S	804_S	0.515	0.21
85_Q	236_I	0.514	0.21
537_I	605_I	0.514	0.21
530_L	830_A	0.514	0.21
39_E	107_F	0.513	0.21
330_I	336_Q	0.513	0.21
82_K	173_S	0.513	0.21
316_F	336_Q	0.513	0.21
681_K	861_G	0.513	0.21
54_Q	106_Q	0.513	0.21
185_V	193_L	0.512	0.21
336_Q	345_L	0.512	0.21
46_V	252_E	0.512	0.21
705_Y	725_I	0.512	0.21
283_R	684_L	0.511	0.21
26_L	832_E	0.511	0.21
698_H	725_I	0.511	0.21
298_C	824_T	0.511	0.21
339_T	366_F	0.511	0.21
702_D	705_Y	0.511	0.21
100_V	149_I	0.510	0.21
520_H	563_D	0.510	0.21
146_L	781_V	0.510	0.21
181_V	762_A	0.510	0.21
263_D	438_S	0.509	0.21
521_N	839_V	0.509	0.21
206_L	279_A	0.509	0.21
671_Y	677_Y	0.508	0.20
769_P	799_S	0.508	0.20
124_L	639_L	0.508	0.20
798_T	818_E	0.508	0.20
379_R	593_R	0.508	0.20
582_R	670_K	0.507	0.20
135_T	551_K	0.507	0.20
606_L	609_I	0.507	0.20
285_I	841_V	0.506	0.20
334_H	821_G	0.506	0.20
343_K	704_Y	0.505	0.20
195_T	816_V	0.505	0.20
89_E	630_K	0.504	0.20
144_A	759_N	0.503	0.20
523_T	819_V	0.503	0.20
171_D	723_Q	0.503	0.20
670_K	678_F	0.503	0.20
257_T	572_I	0.502	0.20
386_M	399_T	0.502	0.20
209_D	826_G	0.502	0.20
533_V	857_H	0.502	0.20
802_D	841_V	0.502	0.20
368_D	373_L	0.501	0.20
353_T	589_I	0.500	0.20

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2olsA	2	0.4434	100	0.538	Contact Map
1vbgA	2	0.4861	100	0.65	Contact Map
2x0sA	2	0.5115	100	0.653	Contact Map
1kblA	2	0.4919	100	0.675	Contact Map
2e28A	3	0.6305	99.9	0.896	Contact Map
3t05A	3	0.6328	99.9	0.896	Contact Map
1zymA	2	0.261	99.9	0.898	Contact Map
2hwgA	2	0.2494	99.9	0.905	Contact Map
2wqdA	2	0.2494	99.9	0.908	Contact Map
2hi6A	1	0.1166	98.2	0.962	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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