GREMLIN Database
YFLH - Uncharacterized protein YflH
UniProt: O34306 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 104 (79)
Sequences: 266 (177)
Seq/√Len: 19.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
92_H96_L4.2571.00
87_E90_K2.9390.99
89_E99_K2.5350.98
79_Q83_S2.2110.94
57_A98_V2.1810.94
32_F97_L2.0310.91
91_E96_L1.9560.90
39_Q42_R1.8470.87
44_K102_D1.7030.82
85_A93_L1.6430.80
37_K101_V1.6390.79
69_E76_M1.6230.79
56_S60_L1.4890.72
76_M79_Q1.4590.71
84_V100_L1.4510.70
85_A96_L1.4510.70
70_P76_M1.4050.68
43_G48_L1.3680.66
68_E71_Q1.3540.65
84_V99_K1.3470.64
58_A90_K1.2590.59
58_A62_D1.2440.58
80_E83_S1.2400.58
32_F68_E1.2320.57
40_V46_L1.2230.57
38_K42_R1.1940.55
81_L96_L1.1850.54
91_E95_Q1.1820.54
40_V101_V1.1810.54
49_D52_K1.1800.54
32_F61_G1.1790.54
32_F35_Y1.1370.51
25_I35_Y1.1290.51
25_I97_L1.0990.49
43_G53_L1.0900.48
77_L93_L1.0870.48
51_G90_K1.0850.48
28_D38_K1.0720.47
37_K40_V1.0590.46
86_D89_E1.0410.45
26_L75_E1.0230.44
64_L78_L1.0120.43
29_F74_E1.0020.43
34_G83_S0.9870.42
44_K70_P0.9830.41
29_F80_E0.9820.41
33_K101_V0.9790.41
24_D27_K0.9770.41
77_L89_E0.9630.40
74_E80_E0.9550.40
31_E70_P0.9490.39
35_Y97_L0.9460.39
54_V95_Q0.9450.39
27_K73_G0.9430.39
29_F39_Q0.9260.38
27_K92_H0.9220.38
79_Q86_D0.9090.37
70_P79_Q0.9040.37
34_G41_N0.9040.37
52_K91_E0.9020.36
33_K81_L0.8940.36
77_L80_E0.8900.36
52_K59_I0.8820.35
63_Y90_K0.8810.35
26_L39_Q0.8650.34
28_D75_E0.8610.34
58_A91_E0.8560.34
58_A87_E0.8470.33
59_I65_A0.8410.33
63_Y75_E0.8320.32
30_E66_K0.8290.32
86_D99_K0.8270.32
55_K90_K0.8130.31
53_L91_E0.7890.30
59_I62_D0.7820.30
73_G76_M0.7680.29
34_G38_K0.7460.28
52_K60_L0.7170.26
26_L78_L0.7090.26
41_N45_K0.7060.26
56_S59_I0.6960.25
31_E62_D0.6920.25
56_S97_L0.6900.25
26_L71_Q0.6590.23
41_N81_L0.6360.22
30_E33_K0.6290.22
92_H95_Q0.6230.22
49_D53_L0.6210.22
32_F53_L0.6040.21
38_K85_A0.6020.21
69_E83_S0.5980.21
65_A83_S0.5860.20
80_E85_A0.5840.20
40_V76_M0.5830.20
56_S83_S0.5710.20
53_L61_G0.5680.19
68_E79_Q0.5670.19
98_V101_V0.5600.19
54_V93_L0.5580.19
76_M83_S0.5550.19
45_K50_D0.5550.19
65_A100_L0.5530.19
48_L98_V0.5390.18
71_Q75_E0.5370.18
65_A84_V0.5350.18
77_L96_L0.5290.18
81_L85_A0.5280.18
24_D45_K0.5190.18
31_E49_D0.5170.17
50_D55_K0.5160.17
55_K61_G0.5150.17
25_I76_M0.5150.17
51_G95_Q0.5140.17
29_F54_V0.5050.17
45_K83_S0.5020.17
89_E95_Q0.5010.17
32_F55_K0.5010.17
40_V77_L0.5000.17
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3d0wA 2 0.8269 100 0.045 Contact Map
3viuA 1 0.5481 19.8 0.927 Contact Map
2q01A 3 0.8846 19.5 0.927 Contact Map
1o2dA 1 0.6731 19.1 0.928 Contact Map
3mzyA 1 0.6827 17.6 0.929 Contact Map
1or7A 2 0.6538 16.4 0.93 Contact Map
1xkpA 1 0.5577 16.3 0.93 Contact Map
1m7sA 4 0.5769 16.2 0.93 Contact Map
3q23A 1 0.9519 15.5 0.931 Contact Map
1mw9X 1 0.5096 14 0.932 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.027 seconds.