TUAD - BACSU - GREMLIN Contacts

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TUAD - UDP-glucose 6-dehydrogenase TuaD

UniProt:	O32271	Sequences: MKKIAVIGTGYVGLVSGTCFAEIGNKVVCCDIDESKIRSLKNGVIPIYEPGLADLVEKNVLDQRLTFTNDIPSAIRASDIIYIAVGTPMSKTGEADLTYVKAAAKTIGEHLNGYKVIVNKSTVPVGTGKLVQSIVQKASKGRYSFDVVSNPEFLREGSAIHDTMNMERAVIGSTSHKAAAIIEELHQPFHAPVIKTNLESAEMIKYAANAFLATKISFINDIANICERVGADVSKVADGVGLDSRIGRKFLKAGIGFGGSCFPKDTTALLQIAKSAGYPFKLIEAVIETNEKQRVHIVDKLLTVMGSVKGRTISVLGLAFKPNTNDVRSAPALDIIPMLQQLGAHVKAYDPIAIPEASAILGEQVEYYTDVYAAMEDTDACLILTDWPEVKEMELVKVKTLLKQPVIIDGRNLFSLEEMQAAGYIYHSIGRPAVRGTEPSDKYFPGLPLEELAKDLGSVNL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	461 (408)
Sequences:	8422 (5062)
Seq/√Len:	250.6

ECOLI - WECC UDG
BACSU - TUAD YWQF YTCA
HALSA - Q9HQQ9 Q9HSW5
SULSO - Q7LXG4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
129_K	199_E	4.700	1.00
34_E	38_R	4.558	1.00
349_Y	390_V	4.067	1.00
3_K	26_K	3.317	1.00
301_L	382_L	3.305	1.00
312_T	345_H	3.243	1.00
323_N	388_P	3.197	1.00
312_T	347_K	3.131	1.00
70_D	73_S	2.975	1.00
39_S	44_V	2.960	1.00
302_L	342_L	2.936	1.00
148_V	182_I	2.757	1.00
196_T	235_K	2.575	1.00
301_L	380_A	2.555	1.00
101_K	130_L	2.541	1.00
105_K	134_I	2.522	1.00
132_Q	147_V	2.520	1.00
314_S	378_T	2.515	1.00
22_E	58_K	2.502	1.00
295_V	338_M	2.413	1.00
315_V	336_I	2.398	1.00
5_A	78_S	2.378	1.00
174_T	178_A	2.353	1.00
227_E	300_K	2.318	1.00
281_K	288_E	2.278	1.00
41_K	67_F	2.259	1.00
38_R	42_N	2.253	1.00
197_N	200_S	2.235	1.00
319_A	353_A	2.174	1.00
379_D	403_K	2.153	1.00
335_I	384_L	2.129	1.00
112_N	115_K	2.101	1.00
161_H	165_N	2.089	1.00
26_K	66_T	2.068	1.00
232_D	235_K	2.054	1.00
25_N	188_P	2.002	1.00
80_I	185_L	1.997	1.00
140_K	143_Y	1.996	1.00
105_K	138_A	1.984	1.00
34_E	69_N	1.941	1.00
313_I	344_A	1.939	1.00
9_T	29_C	1.915	1.00
347_K	378_T	1.910	1.00
105_K	137_K	1.898	1.00
71_I	106_T	1.893	1.00
26_K	64_R	1.876	1.00
196_T	204_I	1.852	1.00
370_D	373_A	1.850	1.00
229_V	276_A	1.849	1.00
399_K	405_P	1.847	1.00
210_A	218_F	1.846	1.00
375_M	398_V	1.843	1.00
208_A	240_V	1.842	1.00
35_S	38_R	1.836	1.00
117_I	135_V	1.823	1.00
146_D	175_S	1.813	1.00
45_I	56_V	1.764	1.00
372_Y	397_K	1.762	1.00
180_A	184_E	1.759	1.00
179_A	195_K	1.753	1.00
81_I	115_K	1.742	1.00
90_S	94_E	1.741	1.00
383_I	413_L	1.736	1.00
347_K	368_Y	1.708	1.00
274_K	284_E	1.688	1.00
203_M	226_C	1.668	1.00
102_A	105_K	1.665	1.00
214_T	286_V	1.656	1.00
108_G	138_A	1.646	1.00
314_S	374_A	1.645	1.00
279_P	284_E	1.638	1.00
33_D	36_K	1.619	1.00
104_A	131_V	1.607	1.00
38_R	41_K	1.599	1.00
179_A	183_E	1.593	1.00
101_K	105_K	1.577	1.00
109_E	138_A	1.576	1.00
114_Y	146_D	1.572	1.00
4_I	185_L	1.557	1.00
3_K	77_A	1.551	1.00
116_V	181_I	1.533	1.00
394_E	397_K	1.510	1.00
5_A	81_I	1.509	1.00
132_Q	136_Q	1.509	1.00
211_F	215_K	1.508	1.00
338_M	341_Q	1.506	1.00
183_E	195_K	1.503	1.00
296_H	300_K	1.492	1.00
284_E	288_E	1.479	1.00
180_A	194_I	1.476	1.00
18_T	56_V	1.466	1.00
388_P	391_K	1.461	1.00
270_L	284_E	1.461	1.00
19_C	22_E	1.459	1.00
31_D	37_I	1.456	1.00
301_L	408_I	1.451	1.00
18_T	65_L	1.446	1.00
228_R	278_Y	1.433	1.00
40_L	67_F	1.430	1.00
39_S	46_P	1.429	1.00
18_T	55_L	1.407	1.00
20_F	185_L	1.402	1.00
53_A	57_E	1.400	1.00
101_K	134_I	1.398	1.00
318_L	348_A	1.395	1.00
322_P	386_D	1.389	1.00
37_I	69_N	1.387	1.00
224_N	296_H	1.385	1.00
30_C	71_I	1.372	1.00
227_E	296_H	1.371	1.00
51_G	54_D	1.370	1.00
54_D	58_K	1.349	1.00
338_M	342_L	1.348	1.00
339_L	344_A	1.345	1.00
130_L	133_S	1.344	1.00
80_I	116_V	1.344	1.00
224_N	293_Q	1.328	1.00
211_F	249_K	1.323	1.00
35_S	39_S	1.322	1.00
3_K	28_V	1.320	1.00
74_A	77_A	1.319	1.00
173_S	179_A	1.318	1.00
111_L	115_K	1.317	1.00
225_I	280_F	1.313	1.00
214_T	218_F	1.309	1.00
333_L	337_P	1.301	1.00
70_D	74_A	1.300	1.00
19_C	164_M	1.285	1.00
255_I	410_G	1.274	1.00
37_I	67_F	1.270	1.00
66_T	74_A	1.269	1.00
298_V	335_I	1.266	1.00
76_R	112_N	1.257	1.00
352_I	389_E	1.236	1.00
184_E	187_Q	1.235	1.00
235_K	238_D	1.226	1.00
300_K	408_I	1.225	1.00
114_Y	177_K	1.221	1.00
282_L	285_A	1.211	1.00
130_L	134_I	1.210	1.00
146_D	178_A	1.191	1.00
173_S	178_A	1.191	1.00
304_V	408_I	1.186	1.00
22_E	164_M	1.185	1.00
108_G	139_S	1.185	1.00
55_L	160_I	1.182	1.00
39_S	42_N	1.172	1.00
41_K	66_T	1.170	1.00
214_T	282_L	1.169	1.00
219_I	237_A	1.165	1.00
407_I	414_F	1.165	1.00
158_S	161_H	1.163	1.00
105_K	109_E	1.163	1.00
98_T	102_A	1.162	1.00
204_I	239_G	1.156	1.00
312_T	377_D	1.154	1.00
146_D	177_K	1.152	1.00
314_S	381_C	1.149	1.00
28_V	78_S	1.149	1.00
80_I	181_I	1.148	1.00
224_N	228_R	1.144	1.00
57_E	61_L	1.142	1.00
282_L	289_T	1.136	1.00
298_V	338_M	1.126	1.00
226_C	233_V	1.123	1.00
7_I	103_A	1.119	1.00
334_D	337_P	1.110	1.00
197_N	235_K	1.109	1.00
104_A	134_I	1.102	1.00
207_A	222_I	1.098	1.00
318_L	358_S	1.097	1.00
316_L	393_M	1.097	1.00
313_I	380_A	1.097	1.00
257_F	287_I	1.096	1.00
375_M	381_C	1.096	1.00
150_N	186_H	1.092	1.00
28_V	66_T	1.087	1.00
181_I	184_E	1.085	1.00
383_I	407_I	1.081	1.00
40_L	65_L	1.079	1.00
314_S	347_K	1.078	1.00
28_V	77_A	1.067	1.00
73_S	76_R	1.066	1.00
104_A	108_G	1.064	1.00
295_V	299_D	1.062	1.00
234_S	252_K	1.058	1.00
108_G	135_V	1.058	1.00
281_K	292_K	1.058	1.00
71_I	110_H	1.055	1.00
162_D	165_N	1.048	1.00
222_I	233_V	1.041	1.00
388_P	392_E	1.041	1.00
187_Q	192_P	1.040	1.00
183_E	187_Q	1.037	1.00
234_S	238_D	1.036	1.00
36_K	46_P	1.036	1.00
7_I	81_I	1.036	1.00
9_T	17_G	1.035	1.00
119_N	131_V	1.033	1.00
77_A	112_N	1.032	1.00
55_L	58_K	1.030	1.00
28_V	68_T	1.030	1.00
336_I	340_Q	1.027	1.00
119_N	128_G	1.016	1.00
88_P	96_D	1.014	1.00
244_S	249_K	1.010	1.00
200_S	231_A	1.004	1.00
356_E	359_A	1.003	1.00
116_V	148_V	0.999	1.00
144_S	177_K	0.997	1.00
22_E	54_D	0.995	1.00
37_I	41_K	0.994	1.00
146_D	174_T	0.993	1.00
383_I	414_F	0.988	1.00
345_H	366_E	0.979	1.00
114_Y	144_S	0.979	1.00
231_A	236_V	0.978	1.00
177_K	181_I	0.975	1.00
308_V	344_A	0.975	1.00
272_I	275_S	0.975	1.00
4_I	20_F	0.974	1.00
175_S	178_A	0.973	1.00
301_L	410_G	0.970	1.00
337_P	340_Q	0.968	1.00
238_D	248_R	0.963	1.00
224_N	292_K	0.963	1.00
178_A	182_I	0.959	1.00
102_A	106_T	0.958	1.00
271_Q	275_S	0.956	1.00
79_D	115_K	0.954	1.00
17_G	29_C	0.954	1.00
334_D	338_M	0.943	1.00
52_L	56_V	0.942	1.00
313_I	382_L	0.935	1.00
132_Q	174_T	0.933	1.00
171_I	182_I	0.932	1.00
9_T	65_L	0.931	1.00
311_R	379_D	0.930	1.00
200_S	236_V	0.930	1.00
183_E	194_I	0.928	1.00
292_K	295_V	0.928	1.00
106_T	109_E	0.925	1.00
337_P	341_Q	0.925	1.00
359_A	366_E	0.924	1.00
304_V	406_V	0.922	1.00
225_I	278_Y	0.921	1.00
83_I	107_I	0.921	1.00
111_L	145_F	0.919	1.00
294_R	334_D	0.916	1.00
129_K	133_S	0.916	1.00
302_L	344_A	0.915	1.00
271_Q	274_K	0.915	1.00
116_V	178_A	0.914	1.00
17_G	65_L	0.911	1.00
255_I	384_L	0.911	1.00
327_V	358_S	0.910	1.00
318_L	330_A	0.909	1.00
368_Y	374_A	0.908	1.00
316_L	381_C	0.906	1.00
396_V	400_T	0.904	1.00
134_I	138_A	0.904	1.00
397_K	400_T	0.904	1.00
353_A	367_Y	0.902	1.00
380_A	406_V	0.901	1.00
5_A	30_C	0.900	1.00
107_I	117_I	0.900	1.00
95_A	124_P	0.899	1.00
302_L	308_V	0.897	1.00
312_T	378_T	0.894	1.00
132_Q	198_L	0.891	1.00
299_D	303_T	0.890	1.00
129_K	198_L	0.889	1.00
128_G	198_L	0.886	1.00
377_D	403_K	0.884	1.00
226_C	236_V	0.882	1.00
135_V	147_V	0.881	1.00
68_T	74_A	0.879	1.00
19_C	163_T	0.878	1.00
332_A	384_L	0.873	1.00
73_S	77_A	0.873	1.00
113_G	144_S	0.872	1.00
213_A	287_I	0.867	0.99
30_C	74_A	0.866	0.99
134_I	137_K	0.863	0.99
180_A	195_K	0.861	0.99
141_G	173_S	0.857	0.99
316_L	390_V	0.851	0.99
183_E	192_P	0.846	0.99
83_I	100_V	0.845	0.99
5_A	28_V	0.844	0.99
4_I	25_N	0.843	0.99
301_L	313_I	0.842	0.99
118_V	182_I	0.841	0.99
79_D	113_G	0.839	0.99
305_M	311_R	0.838	0.99
310_G	345_H	0.837	0.99
16_S	163_T	0.836	0.99
24_G	188_P	0.836	0.99
80_I	118_V	0.836	0.99
32_I	106_T	0.832	0.99
79_D	181_I	0.832	0.99
280_F	283_I	0.830	0.99
395_L	414_F	0.828	0.99
318_L	327_V	0.827	0.99
347_K	366_E	0.825	0.99
114_Y	145_F	0.820	0.99
66_T	73_S	0.818	0.99
215_K	251_L	0.811	0.99
180_A	183_E	0.807	0.99
80_I	182_I	0.804	0.99
30_C	68_T	0.804	0.99
300_K	303_T	0.803	0.99
314_S	375_M	0.800	0.99
270_L	283_I	0.797	0.99
104_A	119_N	0.796	0.99
71_I	109_E	0.796	0.99
179_A	194_I	0.792	0.99
5_A	75_I	0.789	0.99
297_I	410_G	0.788	0.99
327_V	353_A	0.787	0.99
298_V	342_L	0.784	0.99
267_T	287_I	0.783	0.99
95_A	268_A	0.781	0.99
133_S	137_K	0.781	0.99
322_P	388_P	0.779	0.99
292_K	299_D	0.775	0.99
368_Y	373_A	0.775	0.99
257_F	266_T	0.774	0.99
340_Q	365_V	0.774	0.99
373_A	376_E	0.774	0.99
316_L	375_M	0.771	0.99
270_L	287_I	0.769	0.99
340_Q	364_Q	0.767	0.99
291_E	334_D	0.766	0.99
347_K	377_D	0.761	0.99
56_V	65_L	0.761	0.99
127_T	131_V	0.760	0.99
301_L	339_L	0.759	0.99
225_I	269_L	0.758	0.99
386_D	411_R	0.757	0.99
327_V	357_A	0.753	0.99
371_V	375_M	0.750	0.99
318_L	336_I	0.747	0.98
23_I	189_F	0.742	0.98
330_A	333_L	0.742	0.98
371_V	389_E	0.740	0.98
228_R	279_P	0.740	0.98
297_I	408_I	0.739	0.98
154_L	163_T	0.737	0.98
327_V	333_L	0.736	0.98
194_I	242_L	0.733	0.98
141_G	145_F	0.730	0.98
28_V	74_A	0.729	0.98
129_K	132_Q	0.729	0.98
340_Q	346_V	0.729	0.98
6_V	17_G	0.728	0.98
107_I	110_H	0.727	0.98
120_K	186_H	0.727	0.98
306_G	311_R	0.726	0.98
233_V	237_A	0.726	0.98
241_G	250_F	0.723	0.98
135_V	138_A	0.719	0.98
113_G	143_Y	0.715	0.98
336_I	348_A	0.714	0.98
81_I	107_I	0.704	0.98
41_K	60_V	0.703	0.98
16_S	20_F	0.703	0.98
211_F	251_L	0.702	0.98
118_V	185_L	0.702	0.98
273_A	280_F	0.702	0.98
148_V	173_S	0.701	0.98
155_R	158_S	0.699	0.98
295_V	334_D	0.697	0.98
75_I	81_I	0.696	0.98
83_I	117_I	0.695	0.98
136_Q	145_F	0.693	0.98
354_I	367_Y	0.693	0.98
48_Y	352_I	0.690	0.97
167_E	244_S	0.690	0.97
234_S	412_N	0.685	0.97
215_K	219_I	0.685	0.97
30_C	106_T	0.685	0.97
355_P	358_S	0.684	0.97
337_P	359_A	0.683	0.97
100_V	127_T	0.682	0.97
305_M	380_A	0.679	0.97
30_C	69_N	0.678	0.97
44_V	52_L	0.676	0.97
225_I	273_A	0.676	0.97
16_S	168_R	0.675	0.97
32_I	99_Y	0.675	0.97
127_T	130_L	0.673	0.97
36_K	39_S	0.673	0.97
358_S	367_Y	0.670	0.97
355_P	369_T	0.670	0.97
9_T	31_D	0.670	0.97
386_D	391_K	0.670	0.97
192_P	242_L	0.668	0.97
19_C	160_I	0.668	0.97
36_K	40_L	0.666	0.97
26_K	77_A	0.666	0.97
381_C	390_V	0.666	0.97
222_I	269_L	0.665	0.97
172_G	179_A	0.665	0.97
218_F	222_I	0.663	0.97
270_L	274_K	0.662	0.97
316_L	383_I	0.661	0.97
183_E	193_V	0.661	0.97
354_I	358_S	0.661	0.97
6_V	16_S	0.661	0.97
174_T	198_L	0.660	0.97
136_Q	141_G	0.659	0.97
83_I	131_V	0.659	0.97
291_E	294_R	0.658	0.97
210_A	283_I	0.658	0.97
119_N	135_V	0.655	0.97
267_T	291_E	0.655	0.97
7_I	71_I	0.654	0.97
200_S	235_K	0.654	0.97
381_C	398_V	0.654	0.97
82_Y	185_L	0.651	0.96
255_I	297_I	0.650	0.96
370_D	397_K	0.650	0.96
54_D	57_E	0.649	0.96
270_L	280_F	0.648	0.96
316_L	371_V	0.645	0.96
44_V	57_E	0.644	0.96
73_S	110_H	0.643	0.96
63_Q	66_T	0.642	0.96
11_Y	328_R	0.642	0.96
128_G	149_S	0.641	0.96
371_V	393_M	0.640	0.96
76_R	110_H	0.640	0.96
170_V	183_E	0.640	0.96
22_E	55_L	0.636	0.96
100_V	104_A	0.636	0.96
348_A	365_V	0.635	0.96
221_D	289_T	0.635	0.96
305_M	313_I	0.633	0.96
266_T	287_I	0.631	0.96
169_A	204_I	0.631	0.96
83_I	119_N	0.631	0.96
274_K	281_K	0.630	0.96
274_K	279_P	0.630	0.96
272_I	276_A	0.630	0.96
305_M	406_V	0.627	0.96
173_S	195_K	0.626	0.96
237_A	253_A	0.625	0.96
154_L	159_A	0.625	0.96
108_G	117_I	0.625	0.96
106_T	110_H	0.625	0.96
44_V	53_A	0.624	0.95
393_M	398_V	0.624	0.95
5_A	74_A	0.623	0.95
23_I	164_M	0.622	0.95
336_I	365_V	0.621	0.95
315_V	382_L	0.620	0.95
294_R	335_I	0.619	0.95
237_A	241_G	0.618	0.95
146_D	181_I	0.618	0.95
395_L	407_I	0.617	0.95
237_A	252_K	0.616	0.95
89_M	267_T	0.616	0.95
348_A	367_Y	0.615	0.95
122_T	265_D	0.615	0.95
111_L	135_V	0.614	0.95
120_K	150_N	0.614	0.95
285_A	288_E	0.614	0.95
238_D	241_G	0.612	0.95
396_V	399_K	0.612	0.95
351_P	390_V	0.611	0.95
177_K	180_A	0.611	0.95
349_Y	371_V	0.610	0.95
30_C	103_A	0.609	0.95
298_V	308_V	0.607	0.95
9_T	40_L	0.606	0.95
170_V	204_I	0.606	0.95
7_I	75_I	0.603	0.95
53_A	56_V	0.601	0.94
219_I	222_I	0.601	0.94
353_A	357_A	0.600	0.94
278_Y	289_T	0.600	0.94
21_A	64_R	0.599	0.94
100_V	119_N	0.598	0.94
224_N	278_Y	0.598	0.94
182_I	186_H	0.598	0.94
170_V	192_P	0.597	0.94
122_T	261_C	0.597	0.94
152_E	261_C	0.595	0.94
24_G	64_R	0.595	0.94
175_S	180_A	0.594	0.94
75_I	115_K	0.594	0.94
81_I	110_H	0.593	0.94
97_L	101_K	0.593	0.94
293_Q	296_H	0.591	0.94
196_T	200_S	0.591	0.94
300_K	304_V	0.590	0.94
170_V	179_A	0.589	0.94
156_E	320_F	0.588	0.94
213_A	257_F	0.588	0.94
281_K	285_A	0.587	0.94
148_V	171_I	0.587	0.94
298_V	302_L	0.586	0.94
280_F	284_E	0.582	0.93
266_T	283_I	0.581	0.93
255_I	322_P	0.581	0.93
25_N	80_I	0.580	0.93
57_E	60_V	0.577	0.93
31_D	69_N	0.576	0.93
90_S	101_K	0.576	0.93
133_S	136_Q	0.576	0.93
294_R	331_P	0.575	0.93
136_Q	144_S	0.575	0.93
140_K	144_S	0.575	0.93
99_Y	103_A	0.575	0.93
299_D	342_L	0.574	0.93
168_R	186_H	0.574	0.93
255_I	335_I	0.573	0.93
327_V	332_A	0.572	0.93
207_A	210_A	0.572	0.93
301_L	308_V	0.571	0.93
209_N	265_D	0.571	0.93
224_N	227_E	0.571	0.93
336_I	384_L	0.569	0.93
340_Q	345_H	0.567	0.93
132_Q	173_S	0.566	0.93
248_R	252_K	0.566	0.93
87_T	121_S	0.566	0.93
366_E	377_D	0.566	0.93
348_A	354_I	0.565	0.92
51_G	160_I	0.564	0.92
52_L	55_L	0.564	0.92
118_V	148_V	0.564	0.92
241_G	246_I	0.563	0.92
375_M	378_T	0.563	0.92
173_S	198_L	0.560	0.92
318_L	332_A	0.559	0.92
168_R	208_A	0.558	0.92
45_I	53_A	0.557	0.92
222_I	226_C	0.556	0.92
71_I	75_I	0.556	0.92
305_M	308_V	0.556	0.92
395_L	398_V	0.554	0.92
37_I	40_L	0.554	0.92
260_S	264_K	0.553	0.92
97_L	130_L	0.553	0.92
305_M	404_Q	0.552	0.92
380_A	408_I	0.552	0.92
56_V	60_V	0.550	0.91
369_T	373_A	0.550	0.91
120_K	168_R	0.548	0.91
282_L	286_V	0.546	0.91
372_Y	375_M	0.546	0.91
281_K	284_E	0.546	0.91
234_S	253_A	0.545	0.91
51_G	55_L	0.544	0.91
223_A	293_Q	0.543	0.91
85_V	99_Y	0.542	0.91
265_D	328_R	0.541	0.91
228_R	276_A	0.540	0.91
120_K	264_K	0.537	0.90
82_Y	186_H	0.537	0.90
243_D	246_I	0.537	0.90
108_G	145_F	0.535	0.90
163_T	189_F	0.532	0.90
336_I	346_V	0.532	0.90
225_I	229_V	0.532	0.90
391_K	413_L	0.532	0.90
98_T	101_K	0.531	0.90
156_E	264_K	0.531	0.90
171_I	193_V	0.531	0.90
217_S	282_L	0.530	0.90
339_L	346_V	0.529	0.90
209_N	261_C	0.527	0.90
94_E	275_S	0.527	0.90
38_R	69_N	0.526	0.90
304_V	380_A	0.525	0.89
362_G	367_Y	0.525	0.89
90_S	93_G	0.525	0.89
227_E	293_Q	0.525	0.89
361_L	365_V	0.524	0.89
203_M	222_I	0.523	0.89
267_T	329_S	0.522	0.89
120_K	156_E	0.522	0.89
58_K	61_L	0.521	0.89
373_A	377_D	0.521	0.89
302_L	306_G	0.520	0.89
97_L	127_T	0.520	0.89
283_I	286_V	0.520	0.89
88_P	329_S	0.519	0.89
40_L	46_P	0.518	0.89
171_I	179_A	0.517	0.89
211_F	219_I	0.515	0.89
287_I	291_E	0.514	0.88
132_Q	135_V	0.513	0.88
257_F	286_V	0.511	0.88
315_V	384_L	0.511	0.88
153_F	208_A	0.511	0.88
200_S	204_I	0.510	0.88
318_L	367_Y	0.510	0.88
88_P	326_D	0.508	0.88
285_A	289_T	0.507	0.88
264_K	320_F	0.507	0.88
27_V	65_L	0.506	0.88
361_L	364_Q	0.505	0.88
394_E	398_V	0.504	0.87
12_V	328_R	0.504	0.87
209_N	321_K	0.503	0.87
167_E	245_R	0.503	0.87
203_M	231_A	0.503	0.87
381_C	407_I	0.501	0.87
48_Y	325_N	0.500	0.87

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2y0cA	4	0.9523	100	0.286	Contact Map
2q3eA	5	0.9371	100	0.295	Contact Map
3gg2A	3	0.9197	100	0.297	Contact Map
2o3jA	4	0.9328	100	0.297	Contact Map
3g79A	2	0.9349	100	0.314	Contact Map
4a7pA	2	0.9262	100	0.317	Contact Map
3ojoA	2	0.8937	100	0.323	Contact Map
3vtfA	2	0.9089	100	0.336	Contact Map
4xr9A	2	0.9284	100	0.341	Contact Map
1mv8A	2	0.9046	100	0.36	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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