GREMLIN Database
GANP - Putative arabinogalactan oligomer transport system permease protein GanP
UniProt: O32261 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 418 (385)
Sequences: 863 (615)
Seq/√Len: 31.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
147_A170_F4.8451.00
326_L330_F4.8441.00
152_D155_H4.3281.00
166_G170_F3.9021.00
311_T320_K3.5881.00
257_I261_F3.5051.00
168_Q172_N3.4211.00
96_G100_D3.2851.00
165_V169_T3.2091.00
164_W170_F3.1651.00
316_S319_S3.0641.00
113_Q117_S3.0071.00
167_F170_F2.9481.00
164_W167_F2.7801.00
257_I262_G2.7591.00
114_H118_E2.7571.00
150_N163_D2.6401.00
113_Q116_I2.5070.99
258_L262_G2.5020.99
76_I79_C2.4810.99
52_I75_V2.4550.99
165_V170_F2.4350.99
112_Y117_S2.4200.99
49_F53_F2.4120.99
274_W277_L2.3910.99
191_V195_L2.3350.99
166_G172_N2.3300.99
258_L263_I2.2970.99
167_F172_N2.2920.99
202_V333_M2.2900.99
76_I141_L2.2170.99
38_F42_G2.1720.99
50_W67_L2.1320.98
35_A39_A2.1320.98
54_T57_T2.1180.98
141_L145_A2.0630.98
167_F171_A2.0430.98
166_G169_T2.0160.98
219_F222_F2.0030.97
273_N276_R1.9810.97
164_W172_N1.9600.97
206_I329_V1.9300.97
105_L110_E1.8570.96
318_F322_R1.8520.96
267_P270_T1.8170.95
63_N67_L1.8140.95
63_N73_I1.7990.95
361_V368_G1.7740.95
306_L328_M1.7660.95
42_G46_N1.7590.95
63_N66_F1.7460.94
169_T387_S1.7240.94
383_S411_T1.7070.94
114_H117_S1.7030.94
174_F177_D1.6940.93
111_Q114_H1.6870.93
272_A276_R1.6750.93
79_C92_A1.6730.93
215_K304_D1.6370.92
47_M50_W1.6070.91
75_V79_C1.5990.91
163_D174_F1.5950.91
339_T342_T1.5840.91
111_Q117_S1.5830.91
109_K113_Q1.5470.90
164_W168_Q1.5460.90
294_V300_Q1.5440.90
36_S44_L1.5430.90
79_C82_L1.5420.90
50_W53_F1.5380.89
115_I118_E1.5360.89
112_Y116_I1.5250.89
48_G67_L1.5010.88
168_Q171_A1.5000.88
48_G51_G1.4860.88
63_N69_A1.4840.88
97_K101_E1.4710.87
79_C83_A1.4610.87
357_G369_T1.4450.86
200_L284_G1.4450.86
272_A368_G1.4440.86
137_I219_F1.4380.86
93_F96_G1.4360.86
36_S39_A1.4280.86
37_F41_F1.4270.86
53_F57_T1.4240.85
36_S42_G1.4220.85
107_S110_E1.4210.85
51_G55_L1.4150.85
128_S376_I1.4120.85
162_I169_T1.4120.85
55_L64_S1.4120.85
279_L290_Y1.4110.85
171_A175_T1.4100.85
275_S355_N1.4100.85
40_V45_L1.4090.85
194_T341_F1.4060.85
258_L261_F1.3810.84
302_I307_Y1.3810.84
393_T397_S1.3650.83
51_G69_A1.3580.83
49_F78_T1.3540.82
50_W73_I1.3500.82
43_D51_G1.3500.82
41_F46_N1.3420.82
359_P367_G1.3420.82
65_V69_A1.3320.81
34_G40_V1.3230.81
59_V73_I1.3200.81
163_D167_F1.3080.80
345_F393_T1.2990.80
196_A277_L1.2990.80
302_I324_I1.2950.79
267_P271_D1.2940.79
189_W234_P1.2890.79
51_G57_T1.2890.79
37_F81_G1.2880.79
349_N353_L1.2860.79
257_I263_I1.2800.79
31_L34_G1.2520.77
213_N300_Q1.2520.77
283_Q354_F1.2460.77
202_V329_V1.2440.77
35_A38_F1.2420.76
163_D170_F1.2380.76
163_D166_G1.2330.76
48_G53_F1.2250.75
66_F69_A1.2230.75
51_G54_T1.2210.75
163_D169_T1.1930.73
162_I166_G1.1920.73
87_V92_A1.1860.73
112_Y118_E1.1840.73
234_P289_P1.1810.73
260_F263_I1.1760.72
279_L350_I1.1680.72
123_V195_L1.1610.71
214_Q317_V1.1600.71
32_F36_S1.1590.71
202_V337_I1.1590.71
202_V283_Q1.1560.71
62_D66_F1.1500.71
326_L333_M1.1430.70
37_F78_T1.1420.70
85_Y88_N1.1400.70
165_V172_N1.1390.70
236_F353_L1.1390.70
259_A262_G1.1370.70
283_Q397_S1.1360.70
397_S401_I1.1300.69
93_F100_D1.1280.69
114_H119_G1.1200.69
233_V264_D1.1200.69
385_Q388_L1.1170.68
63_N68_L1.1160.68
119_G122_Y1.1130.68
33_L38_F1.1110.68
291_I340_Q1.1080.68
106_S113_Q1.1010.67
164_W169_T1.0980.67
47_M53_F1.0930.67
98_Q101_E1.0890.66
43_D47_M1.0880.66
67_L77_V1.0860.66
285_W313_D1.0810.66
166_G174_F1.0800.66
259_A264_D1.0800.66
89_L99_R1.0740.65
39_A264_D1.0730.65
247_N250_F1.0700.65
196_A280_I1.0680.65
75_V195_L1.0640.65
73_I93_F1.0600.64
90_R101_E1.0450.63
29_V32_F1.0430.63
36_S129_L1.0410.63
395_L399_F1.0410.63
96_G99_R1.0380.63
39_A44_L1.0380.63
330_F333_M1.0320.62
78_T83_A1.0220.61
56_G64_S1.0180.61
222_F226_I1.0160.61
261_F264_D1.0070.60
307_Y325_T1.0060.60
189_W232_A1.0000.60
375_W379_L0.9990.60
296_T300_Q0.9930.59
110_E403_I0.9900.59
46_N50_W0.9890.59
139_P150_N0.9820.58
206_I326_L0.9810.58
62_D73_I0.9800.58
39_A43_D0.9800.58
38_F44_L0.9800.58
51_G67_L0.9770.58
29_V33_L0.9770.58
384_S388_L0.9760.58
288_F371_I0.9760.58
82_L89_L0.9750.58
75_V80_F0.9720.57
78_T82_L0.9720.57
269_M355_N0.9700.57
68_L79_C0.9670.57
165_V171_A0.9620.57
35_A264_D0.9600.56
61_R65_V0.9580.56
42_G49_F0.9580.56
98_Q106_S0.9580.56
77_V81_G0.9560.56
70_E73_I0.9510.56
237_V403_I0.9470.55
374_S393_T0.9440.55
93_F218_R0.9410.55
239_I286_L0.9400.55
38_F43_D0.9380.55
357_G378_K0.9380.55
83_A178_I0.9370.55
302_I329_V0.9360.55
94_Q97_K0.9330.54
49_F222_F0.9320.54
91_D95_S0.9300.54
114_H128_S0.9300.54
286_L343_F0.9260.54
235_G345_F0.9260.54
147_A151_Y0.9210.53
40_V44_L0.9170.53
163_D168_Q0.9150.53
259_A263_I0.9150.53
187_L326_L0.9110.53
71_G77_V0.9100.52
33_L58_E0.9090.52
117_S129_L0.9080.52
108_L111_Q0.9070.52
46_N53_F0.9030.52
174_F379_L0.9010.52
398_V405_L0.8910.51
74_A81_G0.8910.51
38_F41_F0.8870.51
44_L47_M0.8870.51
309_A329_V0.8860.51
330_F347_N0.8850.50
241_I404_A0.8830.50
87_V222_F0.8720.49
146_L149_T0.8710.49
194_T397_S0.8700.49
91_D122_Y0.8680.49
85_Y89_L0.8650.49
273_N277_L0.8650.49
192_V375_W0.8630.49
113_Q118_E0.8630.49
384_S387_S0.8610.48
109_K118_E0.8610.48
42_G47_M0.8540.48
362_T403_I0.8530.48
62_D68_L0.8470.47
44_L48_G0.8450.47
115_I123_V0.8440.47
225_T382_Q0.8430.47
79_C87_V0.8430.47
142_F250_F0.8420.47
283_Q346_N0.8390.47
257_I260_F0.8390.47
136_V283_Q0.8370.47
166_G171_A0.8370.47
255_H263_I0.8330.46
345_F373_V0.8310.46
40_V72_I0.8290.46
167_F174_F0.8290.46
142_F147_A0.8260.46
73_I85_Y0.8260.46
235_G286_L0.8250.46
111_Q124_V0.8250.46
34_G191_V0.8250.46
90_R97_K0.8240.46
148_F151_Y0.8210.45
30_F266_L0.8140.45
98_Q103_K0.8130.45
266_L274_W0.8120.45
45_L50_W0.8080.44
50_W57_T0.8070.44
401_I404_A0.8070.44
206_I295_S0.8040.44
111_Q118_E0.8030.44
139_P148_F0.8010.44
224_R350_I0.8000.44
33_L36_S0.8000.44
87_V99_R0.7990.43
290_Y293_L0.7980.43
376_I389_A0.7960.43
43_D46_N0.7960.43
231_W354_F0.7950.43
194_T223_F0.7920.43
35_A47_M0.7920.43
31_L312_I0.7920.43
165_V168_Q0.7920.43
94_Q101_E0.7900.43
41_F47_M0.7890.43
198_S341_F0.7860.42
59_V63_N0.7860.42
168_Q398_V0.7840.42
97_K100_D0.7820.42
164_W171_A0.7760.42
182_T376_I0.7730.41
89_L184_F0.7720.41
47_M191_V0.7690.41
86_Y95_S0.7650.41
59_V65_V0.7630.41
255_H258_L0.7630.41
231_W290_Y0.7630.41
80_F184_F0.7590.40
233_V317_V0.7560.40
389_A408_F0.7550.40
239_I346_N0.7540.40
189_W335_P0.7530.40
170_F174_F0.7530.40
166_G308_E0.7530.40
206_I336_I0.7510.40
99_R105_L0.7510.40
286_L373_V0.7490.40
40_V48_G0.7480.39
138_F201_Q0.7480.39
271_D274_W0.7480.39
116_I126_G0.7480.39
99_R261_F0.7440.39
61_R73_I0.7430.39
246_F354_F0.7430.39
278_A354_F0.7400.39
33_L47_M0.7400.39
39_A46_N0.7370.39
369_T379_L0.7350.38
258_L272_A0.7330.38
41_F54_T0.7310.38
62_D69_A0.7310.38
353_L375_W0.7300.38
52_I64_S0.7300.38
190_T287_G0.7290.38
197_A393_T0.7290.38
67_L73_I0.7290.38
228_I231_W0.7250.38
190_T374_S0.7240.38
233_V379_L0.7240.38
242_F345_F0.7230.38
359_P370_D0.7220.37
59_V125_S0.7200.37
138_F391_A0.7190.37
93_F97_K0.7160.37
264_D270_T0.7160.37
118_E121_P0.7160.37
39_A58_E0.7140.37
42_G50_W0.7120.37
214_Q295_S0.7110.37
307_Y320_K0.7110.37
31_L137_I0.7100.37
41_F78_T0.7100.37
200_L283_Q0.7050.36
163_D172_N0.7050.36
35_A77_V0.7040.36
160_K164_W0.6990.36
295_S299_L0.6980.36
330_F413_S0.6960.36
164_W194_T0.6920.35
34_G58_E0.6920.35
171_A174_F0.6910.35
242_F393_T0.6890.35
361_V364_S0.6870.35
355_N359_P0.6830.35
259_A265_P0.6830.35
82_L86_Y0.6810.34
319_S322_R0.6790.34
68_L71_G0.6770.34
46_N79_C0.6770.34
38_F47_M0.6760.34
62_D85_Y0.6760.34
351_I355_N0.6760.34
165_V303_P0.6750.34
343_F376_I0.6740.34
33_L270_T0.6710.34
388_L395_L0.6710.34
160_K166_G0.6700.34
270_T385_Q0.6700.34
371_I374_S0.6690.34
169_T172_N0.6680.33
80_F104_P0.6670.33
92_A99_R0.6660.33
79_C395_L0.6660.33
66_F70_E0.6650.33
48_G55_L0.6650.33
278_A281_L0.6640.33
93_F326_L0.6630.33
50_W54_T0.6610.33
411_T415_K0.6610.33
233_V252_A0.6610.33
212_V394_I0.6610.33
41_F58_E0.6600.33
166_G254_N0.6600.33
190_T303_P0.6590.33
35_A42_G0.6580.33
193_W232_A0.6550.33
35_A191_V0.6540.32
107_S117_S0.6520.32
58_E61_R0.6510.32
194_T198_S0.6510.32
284_G353_L0.6480.32
99_R104_P0.6480.32
106_S118_E0.6470.32
293_L336_I0.6470.32
169_T219_F0.6460.32
29_V90_R0.6460.32
39_A49_F0.6450.32
285_W372_L0.6440.32
113_Q125_S0.6420.32
198_S212_V0.6420.32
259_A281_L0.6420.32
245_L262_G0.6410.32
168_Q395_L0.6390.31
73_I76_I0.6390.31
44_L53_F0.6390.31
228_I293_L0.6370.31
99_R103_K0.6350.31
38_F51_G0.6310.31
152_D156_S0.6310.31
162_I170_F0.6300.31
77_V221_R0.6300.31
146_L403_I0.6290.31
46_N83_A0.6280.31
187_L191_V0.6260.31
127_P376_I0.6260.31
261_F399_F0.6250.30
39_A82_L0.6250.30
197_A289_P0.6250.30
246_F284_G0.6250.30
79_C84_V0.6240.30
284_G290_Y0.6230.30
107_S118_E0.6230.30
189_W404_A0.6180.30
43_D57_T0.6170.30
160_K170_F0.6160.30
95_S98_Q0.6150.30
36_S46_N0.6150.30
131_I141_L0.6140.30
88_N91_D0.6120.30
77_V395_L0.6110.29
47_M70_E0.6110.29
39_A59_V0.6100.29
39_A89_L0.6090.29
246_F278_A0.6090.29
214_Q336_I0.6080.29
114_H125_S0.6050.29
51_G78_T0.6050.29
130_F264_D0.6040.29
49_F56_G0.6040.29
47_M57_T0.6040.29
69_A79_C0.6030.29
116_I119_G0.6030.29
103_K191_V0.6030.29
275_S341_F0.6000.29
62_D65_V0.6000.29
342_T400_V0.5990.29
173_I177_D0.5980.29
41_F52_I0.5980.29
357_G375_W0.5970.29
236_F347_N0.5970.29
219_F409_R0.5950.28
412_K416_E0.5950.28
304_D311_T0.5920.28
71_G82_L0.5920.28
153_L384_S0.5880.28
237_V270_T0.5870.28
35_A50_W0.5870.28
383_S389_A0.5870.28
206_I333_M0.5840.28
399_F403_I0.5830.28
127_P230_P0.5820.28
39_A42_G0.5790.27
258_L268_W0.5790.27
197_A234_P0.5790.27
189_W346_N0.5780.27
340_Q343_F0.5770.27
308_E315_A0.5760.27
385_Q389_A0.5750.27
85_Y90_R0.5750.27
102_N105_L0.5730.27
164_W174_F0.5720.27
79_C101_E0.5720.27
133_I330_F0.5710.27
37_F44_L0.5700.27
46_N49_F0.5690.27
61_R67_L0.5680.27
117_S128_S0.5680.27
65_V73_I0.5670.27
267_P274_W0.5660.27
379_L387_S0.5650.26
109_K215_K0.5650.26
224_R296_T0.5640.26
95_S399_F0.5640.26
276_R375_W0.5620.26
178_I362_T0.5610.26
94_Q233_V0.5580.26
228_I292_F0.5570.26
66_F80_F0.5570.26
69_A237_V0.5560.26
84_V144_F0.5560.26
72_I84_V0.5560.26
49_F326_L0.5550.26
46_N77_V0.5550.26
42_G80_F0.5550.26
59_V67_L0.5540.26
291_I350_I0.5540.26
61_R66_F0.5540.26
238_T324_I0.5540.26
51_G58_E0.5530.26
376_I396_L0.5510.26
32_F304_D0.5510.26
189_W347_N0.5500.26
345_F403_I0.5500.26
310_A398_V0.5490.25
66_F74_A0.5490.25
267_P403_I0.5480.25
46_N70_E0.5450.25
84_V105_L0.5450.25
342_T377_Y0.5440.25
54_T161_L0.5440.25
151_Y170_F0.5440.25
241_I291_I0.5430.25
214_Q339_T0.5430.25
369_T375_W0.5430.25
202_V330_F0.5420.25
193_W359_P0.5410.25
310_A320_K0.5400.25
130_F298_V0.5390.25
95_S99_R0.5370.25
271_D367_G0.5370.25
186_V226_I0.5370.25
219_F272_A0.5360.25
204_L284_G0.5350.25
240_L354_F0.5340.25
49_F62_D0.5340.25
59_V70_E0.5340.25
266_L270_T0.5330.25
71_G85_Y0.5320.24
165_V337_I0.5320.24
108_L112_Y0.5310.24
353_L379_L0.5300.24
52_I66_F0.5290.24
48_G57_T0.5290.24
56_G63_N0.5290.24
275_S397_S0.5260.24
34_G49_F0.5240.24
36_S49_F0.5240.24
61_R69_A0.5230.24
280_I346_N0.5230.24
238_T248_D0.5210.24
206_I316_S0.5200.24
108_L117_S0.5200.24
205_G389_A0.5190.24
144_F342_T0.5170.24
53_F58_E0.5170.24
76_I80_F0.5170.24
77_V261_F0.5160.23
199_T360_A0.5160.23
79_C196_A0.5140.23
205_G234_P0.5140.23
404_A408_F0.5090.23
195_L360_A0.5090.23
292_F354_F0.5090.23
139_P151_Y0.5090.23
191_V402_S0.5090.23
189_W370_D0.5090.23
237_V340_Q0.5080.23
45_L48_G0.5060.23
229_L345_F0.5050.23
162_I165_V0.5040.23
192_V276_R0.5030.23
247_N278_A0.5020.23
35_A82_L0.5010.23
56_G62_D0.5010.23
66_F73_I0.5000.23
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4tquM 1 0.6746 100 0.556 Contact Map
2onkC 2 0.6029 100 0.591 Contact Map
3rlfF 1 0.8445 100 0.593 Contact Map
3d31C 2 0.5933 100 0.605 Contact Map
3rlfG 1 0.6531 100 0.626 Contact Map
4tquN 1 0.6388 100 0.635 Contact Map
4ymuD 2 0.5144 100 0.714 Contact Map
3tuiA 2 0.5 100 0.722 Contact Map
2m20A 2 0.0837 7.6 0.975 Contact Map
4lz6A 1 0.5239 6.6 0.975 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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