YVBW - BACSU - GREMLIN Contacts

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YVBW - Uncharacterized amino acid permease YvbW

UniProt:	O32257	Sequences: MKNDNQTLKRTMTSRHIMMMALGGAIGAGLFKGSSSAIDVAGPSVIIAYLLGGIILLFIMQGLAEMAVRNRNARTFRDLVQQVLGNYAAYFLDWIYWKMWVLNIAAEAVVAAIFIQYWLPGCPIWVLALGISLIVTIVNLLSVKIFAETEYWLAMIKITVIIIFIILGLLLLFVSFGDHTASGFSNLTDHGGFFPHGGTGLITAMLVVIYSYGGTEIIGVTLAETKNPEKVVPKAVRSTLTRIVAFYLLPFFIIVSLIPWNQVNSVPESPFVMVFKMVGIPGADHIMNAVILLAIISSMNSGLYGSSRILYTQASDGRLPKVFSKLSSKNVPMFAILMCTSSLYIGVLISLFAGSQTFNYLMGSLGYTVLFIWLIIGFAHLKSRKQQTETPAYYVKWFPYTTWFAIVALLAILIGVIMTTSIVITGITAAIYLLITVAYLVKGRKHQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	447 (419)
Sequences:	24650 (15899)
Seq/√Len:	776.7

ECOLI - YIFK PROY GABP ANSP LYSP AROP PHEP MMUP FRLA CYCA POTE PUUP PLAP ADIC YBAT YCAM YGJI GADC YJEM ARCD YJEH CADB TNAB MTR
BACSU - YVBW GABP YTNA ROCC YDGF YBXG YBGF AAPA HUTM STET ROCE YBEC ASPP YCGH YHDG YFNA ARCD YECA YDAO GERAB GERBB YNDE GERKB YFKT
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97XM0 Q97U05 Q97X49 Q97WS3 Q97Z63 Q7LXI7 Q97ZB5 Q97WD4 Q97VA6 Q97U33 Q97VR4 Q97VA8 Q97Y76 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
136_T	340_T	4.449	1.00
322_V	334_F	4.299	1.00
382_K	386_Q	3.274	1.00
53_G	244_V	3.230	1.00
374_L	406_I	3.136	1.00
325_K	334_F	3.057	1.00
230_K	234_K	3.013	1.00
225_T	231_V	2.826	1.00
13_T	226_K	2.809	1.00
77_R	316_D	2.793	1.00
428_T	432_Y	2.723	1.00
93_D	313_Q	2.656	1.00
432_Y	436_T	2.647	1.00
314_A	324_S	2.593	1.00
18_M	238_S	2.561	1.00
327_S	333_M	2.514	1.00
227_N	230_K	2.509	1.00
129_L	344_Y	2.509	1.00
168_G	253_I	2.505	1.00
223_A	315_S	2.472	1.00
322_V	325_K	2.406	1.00
65_E	384_R	2.368	1.00
282_G	286_I	2.360	1.00
377_G	405_A	2.356	1.00
14_S	238_S	2.341	1.00
81_Q	89_A	2.245	1.00
224_E	308_R	2.244	1.00
337_L	341_S	2.230	1.00
166_I	170_L	2.193	1.00
137_I	141_L	2.164	1.00
136_T	336_I	2.135	1.00
403_W	407_V	2.134	1.00
14_S	231_V	2.131	1.00
311_Y	315_S	2.124	1.00
133_L	344_Y	2.099	1.00
14_S	18_M	2.091	1.00
144_K	148_E	2.068	1.00
17_I	225_T	2.044	1.00
128_A	347_V	2.020	1.00
434_L	438_A	2.017	1.00
426_G	430_A	2.011	1.00
84_L	382_K	2.009	1.00
140_L	333_M	1.981	1.00
273_M	276_K	1.976	1.00
234_K	238_S	1.946	1.00
317_G	321_K	1.946	1.00
18_M	242_R	1.945	1.00
37_A	45_V	1.932	1.00
155_M	159_T	1.920	1.00
13_T	16_H	1.916	1.00
8_L	326_L	1.905	1.00
97_W	339_C	1.893	1.00
323_F	338_M	1.887	1.00
62_G	377_G	1.876	1.00
129_L	347_V	1.863	1.00
54_I	58_F	1.842	1.00
81_Q	86_N	1.842	1.00
84_L	378_F	1.805	1.00
259_P	262_Q	1.802	1.00
327_S	331_V	1.792	1.00
237_R	241_T	1.783	1.00
139_N	300_N	1.777	1.00
80_V	92_L	1.732	1.00
227_N	231_V	1.718	1.00
430_A	434_L	1.713	1.00
133_L	340_T	1.707	1.00
378_F	406_I	1.702	1.00
273_M	277_M	1.687	1.00
16_H	151_Y	1.682	1.00
262_Q	277_M	1.681	1.00
48_A	204_A	1.680	1.00
132_S	343_L	1.674	1.00
92_L	375_I	1.663	1.00
44_S	201_L	1.656	1.00
108_A	299_M	1.653	1.00
400_Y	404_F	1.640	1.00
140_L	337_L	1.636	1.00
12_M	16_H	1.624	1.00
382_K	385_K	1.618	1.00
329_K	333_M	1.610	1.00
21_A	239_T	1.604	1.00
55_I	408_A	1.592	1.00
407_V	411_A	1.591	1.00
241_T	245_A	1.589	1.00
85_G	88_A	1.588	1.00
104_I	343_L	1.569	1.00
159_T	163_I	1.547	1.00
123_P	126_V	1.529	1.00
115_I	127_L	1.523	1.00
432_Y	435_I	1.520	1.00
58_F	404_F	1.477	1.00
73_A	223_A	1.470	1.00
52_G	208_V	1.455	1.00
141_L	329_K	1.454	1.00
108_A	132_S	1.453	1.00
310_L	335_A	1.451	1.00
129_L	133_L	1.449	1.00
221_T	304_Y	1.446	1.00
425_T	428_T	1.442	1.00
160_V	290_V	1.440	1.00
388_T	391_P	1.425	1.00
9_K	330_N	1.422	1.00
8_L	311_Y	1.420	1.00
227_N	234_K	1.419	1.00
306_S	339_C	1.406	1.00
158_I	162_I	1.401	1.00
60_M	240_L	1.399	1.00
311_Y	326_L	1.397	1.00
334_F	338_M	1.396	1.00
80_V	375_I	1.387	1.00
228_P	233_P	1.386	1.00
267_P	273_M	1.385	1.00
435_I	439_Y	1.384	1.00
378_F	382_K	1.379	1.00
111_A	292_L	1.370	1.00
321_K	325_K	1.368	1.00
132_S	340_T	1.367	1.00
169_L	253_I	1.352	1.00
54_I	404_F	1.352	1.00
307_S	336_I	1.350	1.00
321_K	324_S	1.347	1.00
423_V	436_T	1.344	1.00
16_H	147_A	1.333	1.00
427_I	431_I	1.332	1.00
136_T	337_L	1.331	1.00
12_M	17_I	1.323	1.00
84_L	88_A	1.318	1.00
183_G	186_N	1.317	1.00
276_K	284_D	1.315	1.00
111_A	131_I	1.306	1.00
325_K	333_M	1.306	1.00
285_H	289_A	1.305	1.00
397_W	401_T	1.295	1.00
44_S	194_F	1.291	1.00
428_T	435_I	1.286	1.00
60_M	236_V	1.276	1.00
70_N	82_Q	1.271	1.00
107_E	298_S	1.260	1.00
245_A	249_L	1.258	1.00
69_R	391_P	1.255	1.00
231_V	234_K	1.251	1.00
170_L	175_S	1.250	1.00
83_V	379_A	1.242	1.00
32_K	110_V	1.240	1.00
59_I	377_G	1.238	1.00
165_I	249_L	1.236	1.00
46_I	252_F	1.235	1.00
172_L	256_S	1.235	1.00
12_M	147_A	1.231	1.00
310_L	319_L	1.226	1.00
381_L	403_W	1.225	1.00
430_A	433_L	1.219	1.00
61_Q	237_R	1.217	1.00
14_S	234_K	1.213	1.00
125_W	129_L	1.212	1.00
436_T	439_Y	1.212	1.00
135_V	299_M	1.205	1.00
78_D	82_Q	1.203	1.00
15_R	19_M	1.198	1.00
269_S	273_M	1.197	1.00
97_W	310_L	1.196	1.00
138_V	149_T	1.190	1.00
62_G	402_T	1.188	1.00
94_W	432_Y	1.188	1.00
427_I	430_A	1.188	1.00
168_G	257_L	1.184	1.00
87_Y	439_Y	1.173	1.00
429_A	433_L	1.171	1.00
25_A	243_I	1.171	1.00
63_L	76_F	1.164	1.00
17_I	235_A	1.157	1.00
411_A	415_G	1.154	1.00
226_K	231_V	1.147	1.00
425_T	432_Y	1.140	1.00
169_L	173_F	1.139	1.00
260_W	263_V	1.138	1.00
21_A	218_I	1.137	1.00
374_L	410_L	1.134	1.00
90_Y	94_W	1.126	1.00
126_V	130_G	1.123	1.00
173_F	176_F	1.122	1.00
433_L	437_V	1.122	1.00
149_T	153_L	1.121	1.00
398_F	402_T	1.111	1.00
72_N	78_D	1.103	1.00
197_G	200_G	1.100	1.00
163_I	167_L	1.094	1.00
65_E	68_V	1.092	1.00
11_T	226_K	1.088	1.00
20_M	221_T	1.087	1.00
130_G	134_I	1.087	1.00
77_R	312_T	1.087	1.00
22_L	242_R	1.083	1.00
426_G	429_A	1.076	1.00
150_E	300_N	1.074	1.00
164_F	168_G	1.073	1.00
385_K	399_P	1.067	1.00
326_L	330_N	1.066	1.00
67_A	79_L	1.064	1.00
38_I	45_V	1.052	1.00
80_V	88_A	1.051	1.00
112_A	127_L	1.045	1.00
162_I	166_I	1.042	1.00
417_I	420_T	1.039	1.00
341_S	345_I	1.033	1.00
115_I	292_L	1.029	1.00
410_L	414_I	1.027	1.00
425_T	430_A	1.023	1.00
421_S	425_T	1.020	1.00
334_F	337_L	1.019	1.00
399_P	403_W	1.017	1.00
400_Y	403_W	1.011	1.00
133_L	137_I	1.011	1.00
184_F	187_L	1.010	1.00
267_P	270_P	1.010	1.00
222_L	232_V	1.008	1.00
391_P	394_Y	1.007	1.00
397_W	400_Y	1.003	1.00
22_L	243_I	1.003	1.00
380_H	402_T	1.001	1.00
276_K	281_P	1.000	1.00
428_T	436_T	0.998	1.00
58_F	401_T	0.994	1.00
50_L	248_L	0.987	1.00
430_A	435_I	0.980	1.00
423_V	426_G	0.975	1.00
136_T	140_L	0.974	1.00
429_A	432_Y	0.974	1.00
148_E	152_W	0.971	1.00
112_A	128_A	0.965	1.00
202_I	411_A	0.964	1.00
431_I	434_L	0.964	1.00
72_N	82_Q	0.963	1.00
423_V	432_Y	0.961	1.00
423_V	427_I	0.960	1.00
140_L	331_V	0.959	1.00
216_E	220_V	0.959	1.00
186_N	189_D	0.958	1.00
140_L	327_S	0.958	1.00
406_I	410_L	0.958	1.00
315_S	324_S	0.955	1.00
435_I	438_A	0.955	1.00
143_V	304_Y	0.946	1.00
271_F	275_F	0.939	1.00
279_G	283_A	0.935	1.00
46_I	255_V	0.933	1.00
194_F	201_L	0.932	1.00
153_L	297_S	0.932	1.00
393_Y	396_K	0.927	1.00
158_I	246_F	0.927	1.00
213_G	369_V	0.924	1.00
170_L	174_V	0.924	1.00
26_I	31_F	0.920	1.00
157_K	294_A	0.911	1.00
280_I	283_A	0.906	1.00
377_G	406_I	0.906	1.00
434_L	437_V	0.905	1.00
259_P	277_M	0.903	1.00
19_M	151_Y	0.901	1.00
74_R	77_R	0.899	1.00
428_T	431_I	0.897	1.00
303_L	340_T	0.895	1.00
374_L	409_L	0.893	1.00
135_V	300_N	0.887	1.00
106_A	362_M	0.887	1.00
426_G	432_Y	0.886	1.00
414_I	418_M	0.886	1.00
82_Q	387_Q	0.880	1.00
26_I	29_G	0.879	1.00
389_E	394_Y	0.879	1.00
333_M	337_L	0.878	1.00
74_R	78_D	0.878	1.00
8_L	308_R	0.877	1.00
106_A	210_Y	0.875	1.00
431_I	435_I	0.874	1.00
425_T	434_L	0.873	1.00
8_L	224_E	0.872	1.00
165_I	253_I	0.872	1.00
53_G	212_Y	0.869	1.00
374_L	378_F	0.868	1.00
68_V	392_A	0.867	1.00
11_T	144_K	0.865	1.00
170_L	173_F	0.865	1.00
134_I	296_I	0.863	1.00
238_S	242_R	0.861	1.00
50_L	54_I	0.860	1.00
422_I	425_T	0.860	1.00
14_S	235_A	0.858	1.00
244_V	248_L	0.857	1.00
172_L	176_F	0.855	1.00
172_L	175_S	0.854	1.00
94_W	319_L	0.851	1.00
428_T	433_L	0.851	1.00
433_L	436_T	0.850	1.00
16_H	148_E	0.847	1.00
275_F	278_V	0.845	1.00
327_S	330_N	0.845	1.00
323_F	334_F	0.842	1.00
281_P	285_H	0.838	1.00
57_L	61_Q	0.837	1.00
47_I	201_L	0.835	1.00
125_W	347_V	0.834	1.00
127_L	130_G	0.833	1.00
185_S	188_T	0.826	1.00
165_I	169_L	0.825	1.00
15_R	151_Y	0.824	1.00
164_F	275_F	0.822	1.00
425_T	436_T	0.822	1.00
81_Q	316_D	0.822	1.00
340_T	344_Y	0.820	1.00
422_I	426_G	0.819	1.00
432_Y	439_Y	0.816	1.00
198_G	201_L	0.815	1.00
112_A	124_I	0.815	1.00
427_I	432_Y	0.812	1.00
381_L	402_T	0.811	1.00
421_S	426_G	0.810	1.00
364_S	368_T	0.801	1.00
396_K	400_Y	0.800	1.00
319_L	323_F	0.800	1.00
111_A	295_I	0.798	1.00
405_A	409_L	0.795	1.00
432_Y	437_V	0.791	1.00
413_L	416_V	0.791	1.00
115_I	119_L	0.790	1.00
390_T	394_Y	0.790	1.00
57_L	237_R	0.790	1.00
26_I	157_K	0.788	1.00
87_Y	91_F	0.783	1.00
58_F	62_G	0.781	1.00
217_I	305_G	0.780	1.00
27_G	31_F	0.778	1.00
431_I	436_T	0.773	1.00
135_V	303_L	0.773	1.00
252_F	256_S	0.772	1.00
148_E	151_Y	0.771	1.00
432_Y	438_A	0.771	1.00
137_I	140_L	0.769	1.00
381_L	385_K	0.768	1.00
402_T	406_I	0.767	1.00
190_H	195_P	0.766	1.00
109_V	361_L	0.763	1.00
379_A	383_S	0.761	1.00
122_C	126_V	0.760	1.00
227_N	233_P	0.759	1.00
88_A	375_I	0.758	1.00
416_V	420_T	0.757	1.00
213_G	373_W	0.755	1.00
430_A	436_T	0.749	1.00
132_S	347_V	0.748	1.00
25_A	239_T	0.748	1.00
233_P	236_V	0.747	1.00
66_M	380_H	0.746	1.00
191_G	194_F	0.746	1.00
257_L	274_V	0.744	1.00
139_N	336_I	0.739	1.00
96_Y	100_W	0.736	1.00
411_A	414_I	0.734	1.00
103_N	365_L	0.734	1.00
169_L	249_L	0.733	1.00
189_D	192_G	0.732	1.00
11_T	143_V	0.730	1.00
18_M	235_A	0.729	1.00
112_A	115_I	0.729	1.00
431_I	438_A	0.729	1.00
173_F	177_G	0.727	1.00
141_L	145_I	0.722	1.00
30_L	250_P	0.721	1.00
15_R	148_E	0.721	1.00
80_V	379_A	0.720	1.00
409_L	412_I	0.719	1.00
187_L	190_H	0.718	1.00
380_H	384_R	0.718	1.00
421_S	436_T	0.718	1.00
425_T	429_A	0.717	1.00
426_G	431_I	0.716	1.00
303_L	307_S	0.715	1.00
426_G	436_T	0.714	1.00
37_A	41_A	0.713	1.00
203_T	207_V	0.713	1.00
308_R	311_Y	0.712	1.00
184_F	256_S	0.708	1.00
111_A	296_I	0.707	1.00
59_I	409_L	0.706	1.00
66_M	79_L	0.705	1.00
307_S	335_A	0.704	1.00
77_R	81_Q	0.702	1.00
341_S	344_Y	0.701	1.00
147_A	151_Y	0.700	1.00
322_V	338_M	0.699	1.00
425_T	439_Y	0.699	1.00
140_L	329_K	0.698	1.00
421_S	428_T	0.697	1.00
423_V	429_A	0.696	1.00
83_V	382_K	0.696	1.00
328_S	333_M	0.689	1.00
139_N	304_Y	0.688	1.00
186_N	190_H	0.688	1.00
310_L	338_M	0.688	1.00
165_I	250_P	0.686	1.00
47_I	51_L	0.685	1.00
101_V	342_S	0.683	1.00
102_L	364_S	0.679	1.00
238_S	241_T	0.672	1.00
43_P	255_V	0.671	1.00
23_G	154_A	0.671	1.00
183_G	187_L	0.669	1.00
172_L	253_I	0.666	1.00
116_Q	120_P	0.665	1.00
129_L	348_L	0.664	1.00
426_G	433_L	0.664	1.00
8_L	11_T	0.664	1.00
69_R	388_T	0.662	1.00
314_A	323_F	0.662	1.00
125_W	128_A	0.659	1.00
174_V	177_G	0.658	1.00
114_F	291_I	0.656	1.00
421_S	434_L	0.653	1.00
229_E	392_A	0.652	1.00
132_S	344_Y	0.651	1.00
421_S	432_Y	0.651	1.00
381_L	399_P	0.649	1.00
323_F	335_A	0.648	1.00
11_T	15_R	0.647	1.00
116_Q	124_I	0.644	1.00
425_T	431_I	0.643	1.00
26_I	33_G	0.642	1.00
184_F	188_T	0.641	1.00
15_R	18_M	0.637	1.00
135_V	296_I	0.637	1.00
428_T	439_Y	0.636	1.00
56_L	215_T	0.636	1.00
249_L	253_I	0.636	1.00
84_L	379_A	0.635	1.00
131_I	299_M	0.634	1.00
63_L	376_I	0.633	1.00
34_S	251_F	0.633	1.00
399_P	402_T	0.632	1.00
405_A	408_A	0.631	1.00
232_V	236_V	0.631	1.00
77_R	93_D	0.628	1.00
224_E	332_P	0.627	1.00
99_M	369_V	0.627	1.00
83_V	383_S	0.627	1.00
368_T	372_I	0.627	1.00
47_I	50_L	0.626	1.00
105_A	361_L	0.626	1.00
105_A	346_G	0.626	1.00
202_I	415_G	0.625	1.00
282_G	285_H	0.623	1.00
213_G	216_E	0.623	1.00
140_L	336_I	0.622	1.00
73_A	311_Y	0.621	1.00
65_E	393_Y	0.620	1.00
69_R	392_A	0.619	1.00
49_Y	211_S	0.619	1.00
147_A	300_N	0.619	1.00
85_G	89_A	0.619	1.00
60_M	215_T	0.619	1.00
242_R	246_F	0.617	1.00
189_D	193_F	0.616	1.00
425_T	433_L	0.615	1.00
117_Y	288_N	0.614	1.00
412_I	416_V	0.612	1.00
427_I	436_T	0.611	1.00
156_I	290_V	0.611	1.00
390_T	393_Y	0.611	1.00
27_G	247_Y	0.611	1.00
107_E	299_M	0.610	1.00
46_I	50_L	0.608	1.00
77_R	89_A	0.608	1.00
384_R	388_T	0.606	1.00
67_A	232_V	0.605	1.00
414_I	417_I	0.605	1.00
220_V	305_G	0.605	1.00
167_L	280_I	0.604	1.00
223_A	311_Y	0.604	1.00
429_A	436_T	0.603	1.00
242_R	245_A	0.602	1.00
64_A	68_V	0.601	1.00
61_Q	401_T	0.601	1.00
76_F	216_E	0.600	1.00
423_V	437_V	0.598	1.00
115_I	131_I	0.598	1.00
143_V	221_T	0.597	1.00
145_I	148_E	0.596	1.00
391_P	395_V	0.595	1.00
225_T	232_V	0.595	1.00
62_G	405_A	0.594	1.00
395_V	398_F	0.593	1.00
95_I	372_I	0.593	1.00
357_T	360_Y	0.591	1.00
219_G	236_V	0.590	1.00
51_L	205_M	0.590	1.00
228_P	231_V	0.590	1.00
24_G	302_G	0.590	1.00
332_P	335_A	0.588	1.00
46_I	49_Y	0.586	1.00
130_G	133_L	0.586	1.00
24_G	301_S	0.585	1.00
46_I	248_L	0.585	1.00
133_L	136_T	0.584	1.00
37_A	208_V	0.584	1.00
52_G	212_Y	0.583	1.00
103_N	106_A	0.583	1.00
18_M	21_A	0.583	1.00
45_V	251_F	0.582	1.00
108_A	112_A	0.582	1.00
289_A	293_L	0.582	1.00
60_M	64_A	0.582	1.00
194_F	197_G	0.582	1.00
359_N	362_M	0.581	1.00
422_I	432_Y	0.580	1.00
107_E	110_V	0.580	1.00
407_V	410_L	0.578	1.00
107_E	295_I	0.577	1.00
183_G	188_T	0.576	1.00
65_E	396_K	0.576	1.00
264_N	267_P	0.575	1.00
118_W	288_N	0.575	1.00
142_S	145_I	0.575	1.00
384_R	398_F	0.574	1.00
40_V	203_T	0.573	1.00
101_V	339_C	0.573	1.00
369_V	372_I	0.571	1.00
388_T	392_A	0.571	1.00
269_S	272_V	0.570	1.00
33_G	362_M	0.570	1.00
52_G	209_I	0.569	1.00
392_A	395_V	0.569	1.00
80_V	89_A	0.569	1.00
145_I	149_T	0.568	1.00
200_G	203_T	0.567	1.00
66_M	83_V	0.565	1.00
250_P	254_I	0.564	1.00
398_F	401_T	0.564	1.00
253_I	256_S	0.563	1.00
194_F	198_G	0.561	1.00
326_L	329_K	0.561	1.00
294_A	297_S	0.561	1.00
409_L	413_L	0.559	1.00
159_T	162_I	0.559	1.00
19_M	154_A	0.559	1.00
76_F	220_V	0.557	1.00
59_I	216_E	0.557	1.00
306_S	310_L	0.557	1.00
100_W	302_G	0.555	1.00
67_A	219_G	0.555	1.00
28_A	210_Y	0.554	1.00
395_V	401_T	0.553	1.00
308_R	332_P	0.553	1.00
136_T	303_L	0.551	1.00
303_L	336_I	0.551	1.00
22_L	154_A	0.551	1.00
13_T	144_K	0.549	1.00
146_F	304_Y	0.549	1.00
310_L	314_A	0.548	1.00
270_P	278_V	0.548	1.00
36_S	359_N	0.546	1.00
26_I	246_F	0.545	1.00
422_I	436_T	0.544	1.00
172_L	257_L	0.544	1.00
397_W	402_T	0.544	1.00
151_Y	155_M	0.542	1.00
119_L	122_C	0.542	1.00
402_T	409_L	0.541	1.00
270_P	274_V	0.541	1.00
43_P	260_W	0.541	1.00
250_P	271_F	0.540	1.00
95_I	371_F	0.540	1.00
345_I	348_L	0.540	1.00
44_S	193_F	0.539	1.00
103_N	107_E	0.538	1.00
150_E	297_S	0.538	1.00
374_L	413_L	0.537	1.00
192_G	195_P	0.537	1.00
31_F	157_K	0.537	1.00
229_E	234_K	0.537	1.00
102_L	365_L	0.537	1.00
229_E	390_T	0.535	1.00
167_L	171_L	0.534	1.00
398_F	403_W	0.533	1.00
58_F	405_A	0.531	1.00
152_W	155_M	0.531	1.00
322_V	326_L	0.529	1.00
265_S	268_E	0.528	1.00
225_T	235_A	0.527	1.00
30_L	33_G	0.527	1.00
24_G	217_I	0.526	1.00
218_I	232_V	0.526	1.00
402_T	416_V	0.525	1.00
198_G	202_I	0.524	1.00
216_E	373_W	0.524	1.00
134_I	138_V	0.522	1.00
270_P	275_F	0.522	1.00
171_L	174_V	0.522	1.00
156_I	160_V	0.520	1.00
168_G	172_L	0.519	1.00
270_P	273_M	0.516	1.00
425_T	435_I	0.516	1.00
423_V	430_A	0.515	1.00
308_R	326_L	0.515	1.00
358_F	362_M	0.514	1.00
65_E	69_R	0.514	1.00
75_T	219_G	0.514	1.00
108_A	135_V	0.513	1.00
154_A	157_K	0.512	1.00
92_L	372_I	0.512	1.00
213_G	365_L	0.512	1.00
110_V	114_F	0.511	1.00
49_Y	251_F	0.511	1.00
333_M	336_I	0.511	1.00
383_S	391_P	0.511	1.00
10_R	226_K	0.508	1.00
431_I	439_Y	0.508	1.00
162_I	165_I	0.507	1.00
62_G	395_V	0.507	1.00
111_A	115_I	0.507	1.00
408_A	412_I	0.506	1.00
32_K	35_S	0.504	1.00
338_M	342_S	0.504	1.00
285_H	288_N	0.503	1.00
230_K	233_P	0.503	1.00
224_E	326_L	0.502	1.00
37_A	204_A	0.501	1.00
143_V	147_A	0.501	1.00
99_M	368_T	0.500	1.00
430_A	437_V	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.9217	100	0.27	Contact Map
3giaA	1	0.9329	100	0.335	Contact Map
4djkA	2	0.915	100	0.337	Contact Map
3dh4A	3	0.9306	99	0.85	Contact Map
2xq2A	2	0.9306	98.9	0.854	Contact Map
2jlnA	1	0.9105	98.8	0.86	Contact Map
2a65A	2	0.9329	98.2	0.885	Contact Map
4wgvA	2	0.8277	98.1	0.885	Contact Map
4xp4A	1	0.9441	97.4	0.902	Contact Map
4us3A	1	0.8747	96.8	0.911	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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