GREMLIN Database
YVBT - Uncharacterized protein YvbT
UniProt: O32254 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 336 (295)
Sequences: 16442 (10491)
Seq/√Len: 610.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
235_N293_E5.3611.00
37_R73_G3.4051.00
78_R110_D2.8051.00
235_N290_G2.7871.00
38_R41_E2.6891.00
138_P185_E2.6771.00
297_K300_D2.5621.00
40_E76_K2.5581.00
234_T237_K2.5461.00
206_E210_N2.5011.00
181_R211_S2.4931.00
71_A105_Y2.4711.00
235_N239_Q2.4361.00
67_I79_V2.3851.00
38_R327_E2.3571.00
290_G293_E2.3391.00
180_A207_L2.2381.00
232_A237_K2.2361.00
299_E303_K2.2331.00
142_E186_L2.2211.00
210_N214_P2.1861.00
37_R41_E2.1721.00
30_R106_P2.1491.00
205_L209_R2.1431.00
212_F221_P2.1271.00
33_M37_R2.1051.00
205_L223_A2.0951.00
36_A70_I2.0431.00
207_L211_S2.0141.00
149_K167_D1.9551.00
47_Y77_I1.9401.00
236_E240_H1.9371.00
202_V206_E1.9261.00
34_D37_R1.9191.00
102_E107_G1.8881.00
324_R327_E1.8701.00
98_F109_I1.8661.00
33_M73_G1.8591.00
71_A79_V1.8461.00
62_A97_Q1.8381.00
48_W80_G1.8251.00
184_G211_S1.8181.00
287_I294_V1.8081.00
243_T247_Q1.7981.00
145_R167_D1.7021.00
36_A47_Y1.6741.00
38_R42_W1.6381.00
142_E146_N1.6301.00
207_L210_N1.6301.00
211_S214_P1.6261.00
98_F111_L1.6251.00
70_I79_V1.6051.00
152_G155_R1.6041.00
38_R323_M1.5991.00
293_E296_A1.5931.00
174_G190_F1.5761.00
233_D324_R1.5601.00
324_R328_I1.5511.00
145_R186_L1.5381.00
181_R214_P1.5381.00
203_P206_E1.5311.00
231_A294_V1.5271.00
292_E296_A1.5081.00
24_T27_E1.4451.00
33_M69_H1.4431.00
295_K299_E1.4391.00
181_R185_E1.4331.00
237_K241_L1.4251.00
299_E302_V1.4131.00
152_G157_Q1.4001.00
41_E75_K1.3971.00
69_H72_G1.3961.00
40_E74_T1.3891.00
293_E297_K1.3881.00
138_P186_L1.3881.00
325_S329_I1.3841.00
145_R170_I1.3841.00
36_A74_T1.3811.00
34_D323_M1.3661.00
225_V307_A1.3581.00
212_F217_V1.3521.00
69_H104_L1.3401.00
49_L67_I1.3271.00
296_A300_D1.3011.00
89_H97_Q1.3001.00
232_A238_A1.2861.00
125_R128_R1.2811.00
291_P328_I1.2781.00
319_H323_M1.2701.00
27_E31_N1.2691.00
160_A163_G1.2631.00
30_R34_D1.2571.00
62_A65_V1.2561.00
222_Y308_D1.2561.00
171_W224_M1.2531.00
181_R215_S1.2491.00
300_D303_K1.2391.00
240_H243_T1.2361.00
230_I241_L1.2301.00
94_I140_Q1.2301.00
237_K240_H1.2221.00
34_D38_R1.2211.00
231_A291_P1.2201.00
177_G207_L1.2151.00
138_P142_E1.2081.00
40_E75_K1.2071.00
185_E215_S1.2051.00
171_W189_P1.2011.00
184_G215_S1.1991.00
259_Q263_P1.1921.00
67_I81_S1.1861.00
289_G294_V1.1781.00
145_R188_L1.1781.00
132_N135_E1.1721.00
211_S215_S1.1711.00
111_L144_L1.1681.00
150_P153_N1.1651.00
181_R207_L1.1651.00
231_A328_I1.1601.00
240_H244_S1.1561.00
80_G110_D1.1551.00
42_W326_F1.1541.00
141_L186_L1.1531.00
36_A77_I1.1491.00
65_V68_G1.1371.00
178_F181_R1.1351.00
61_S100_T1.1311.00
242_A246_Y1.1271.00
198_P300_D1.1251.00
233_D237_K1.1221.00
113_L141_L1.1211.00
143_E155_R1.1131.00
49_L70_I1.1121.00
144_L148_F1.1101.00
101_L109_I1.1031.00
164_E167_D1.0951.00
64_A97_Q1.0851.00
153_N157_Q1.0781.00
135_E178_F1.0771.00
202_V305_T1.0771.00
119_T123_T1.0691.00
287_I297_K1.0681.00
65_V101_L1.0651.00
37_R75_K1.0641.00
124_A129_R1.0511.00
261_K264_V1.0471.00
212_F218_L1.0411.00
34_D319_H1.0391.00
136_D139_E1.0351.00
93_V97_Q1.0351.00
31_N34_D1.0341.00
69_H73_G1.0341.00
197_S200_N1.0331.00
203_P207_L1.0311.00
222_Y309_E1.0221.00
143_E146_N1.0151.00
146_N151_S1.0151.00
102_E165_G1.0131.00
41_E327_E1.0111.00
239_Q243_T1.0071.00
200_N203_P1.0031.00
242_A288_V1.0001.00
325_S328_I0.9961.00
146_N150_P0.9911.00
83_G173_L0.9841.00
102_E166_I0.9841.00
135_E151_S0.9821.00
229_I312_V0.9801.00
26_A30_R0.9731.00
23_G31_N0.9711.00
227_V287_I0.9701.00
183_A190_F0.9701.00
139_E143_E0.9681.00
277_A280_N0.9601.00
182_L186_L0.9591.00
46_R80_G0.9581.00
259_Q262_P0.9571.00
227_V298_L0.9551.00
236_E239_Q0.9451.00
64_A84_I0.9441.00
145_R149_K0.9371.00
140_Q144_L0.9371.00
106_P163_G0.9321.00
138_P182_L0.9301.00
213_T218_L0.9281.00
31_N319_H0.9281.00
132_N136_D0.9211.00
180_A211_S0.9191.00
232_A241_L0.9161.00
124_A130_N0.9131.00
191_A224_M0.9011.00
312_V329_I0.9011.00
30_R33_M0.9011.00
209_R223_A0.8911.00
91_S143_E0.8761.00
296_A299_E0.8721.00
83_G114_G0.8701.00
34_D41_E0.8651.00
123_T128_R0.8621.00
231_A329_I0.8621.00
260_L263_P0.8581.00
126_A129_R0.8561.00
250_L254_R0.8561.00
136_D140_Q0.8461.00
198_P202_V0.8451.00
67_I71_A0.8441.00
102_E167_D0.8441.00
123_T126_A0.8431.00
46_R309_E0.8391.00
29_F104_L0.8371.00
172_L183_A0.8371.00
241_L244_S0.8361.00
150_P155_R0.8311.00
244_S247_Q0.8291.00
239_Q242_A0.8291.00
142_E155_R0.8211.00
71_A109_I0.8121.00
68_G72_G0.8111.00
250_L253_V0.8031.00
239_Q283_L0.8001.00
180_A184_G0.8001.00
103_T166_I0.7961.00
28_S31_N0.7961.00
85_M116_A0.7951.00
205_L208_Y0.7901.00
265_E274_Y0.7891.00
72_G105_Y0.7871.00
233_D328_I0.7871.00
124_A127_L0.7871.00
212_F215_S0.7861.00
148_F168_V0.7851.00
134_G178_F0.7851.00
208_Y212_F0.7831.00
160_A164_E0.7811.00
71_A101_L0.7801.00
126_A130_N0.7791.00
244_S248_R0.7791.00
86_L94_I0.7771.00
190_F208_Y0.7771.00
86_L140_Q0.7771.00
243_T246_Y0.7721.00
234_T238_A0.7721.00
229_I329_I0.7691.00
278_M282_Q0.7631.00
123_T127_L0.7631.00
94_I144_L0.7631.00
138_P178_F0.7611.00
278_M281_E0.7581.00
206_E306_Q0.7551.00
323_M327_E0.7541.00
29_F69_H0.7521.00
33_M70_I0.7521.00
158_V161_I0.7511.00
131_I178_F0.7501.00
124_A128_R0.7461.00
209_R213_T0.7391.00
180_A190_F0.7391.00
78_R169_P0.7311.00
146_N149_K0.7301.00
67_I109_I0.7291.00
181_R210_N0.7271.00
67_I101_L0.7271.00
98_F148_F0.7251.00
172_L179_S0.7251.00
248_R251_D0.7241.00
199_A202_V0.7231.00
110_D171_W0.7201.00
102_E164_E0.7201.00
99_G158_V0.7151.00
276_K279_V0.7151.00
212_F219_D0.7131.00
83_G94_I0.7111.00
258_N261_K0.7111.00
127_L130_N0.7071.00
172_L187_G0.7061.00
142_E185_E0.7051.00
91_S140_Q0.7051.00
146_N153_N0.7041.00
25_I28_S0.7031.00
125_R129_R0.7021.00
115_R133_S0.7021.00
53_H96_E0.7021.00
239_Q288_V0.7001.00
89_H93_V0.6981.00
48_W82_G0.6971.00
172_L182_L0.6961.00
153_N156_N0.6951.00
177_G211_S0.6951.00
224_M309_E0.6941.00
246_Y249_F0.6911.00
81_S109_I0.6901.00
90_S93_V0.6881.00
255_G258_N0.6821.00
208_Y221_P0.6821.00
233_D291_P0.6801.00
51_E89_H0.6781.00
177_G181_R0.6781.00
212_F220_E0.6751.00
31_N35_L0.6751.00
80_G171_W0.6731.00
115_R137_F0.6731.00
209_R308_D0.6711.00
247_Q251_D0.6681.00
174_G179_S0.6671.00
276_K280_N0.6651.00
302_V307_A0.6631.00
49_L66_L0.6621.00
262_P265_E0.6581.00
46_R311_M0.6581.00
178_F182_L0.6571.00
33_M72_G0.6521.00
30_R72_G0.6511.00
132_N151_S0.6501.00
39_A326_F0.6501.00
45_H76_K0.6491.00
226_G311_M0.6481.00
205_L305_T0.6451.00
259_Q264_V0.6451.00
40_E77_I0.6411.00
64_A98_F0.6401.00
147_Y153_N0.6401.00
79_V105_Y0.6391.00
92_L147_Y0.6381.00
223_A307_A0.6381.00
265_E273_P0.6371.00
102_E105_Y0.6361.00
121_Q124_A0.6341.00
235_N238_A0.6341.00
159_R162_P0.6321.00
39_A77_I0.6321.00
47_Y70_I0.6311.00
103_T163_G0.6301.00
248_R252_L0.6291.00
298_L310_I0.6291.00
45_H78_R0.6281.00
68_G101_L0.6271.00
33_M36_A0.6261.00
142_E145_R0.6241.00
298_L312_V0.6231.00
74_T108_R0.6181.00
30_R75_K0.6161.00
139_E142_E0.6161.00
232_A235_N0.6101.00
68_G105_Y0.6091.00
251_D254_R0.6091.00
169_P222_Y0.6071.00
29_F33_M0.6071.00
292_E295_K0.6061.00
185_E211_S0.6051.00
161_I164_E0.6041.00
201_T204_A0.6031.00
261_K265_E0.6001.00
89_H94_I0.5961.00
137_F140_Q0.5951.00
229_I287_I0.5941.00
192_F204_A0.5941.00
146_N155_R0.5921.00
113_L144_L0.5911.00
42_W323_M0.5891.00
184_G212_F0.5891.00
66_L100_T0.5881.00
135_E152_G0.5861.00
314_S326_F0.5851.00
86_L113_L0.5841.00
122_L125_R0.5821.00
215_S218_L0.5821.00
314_S329_I0.5821.00
185_E214_P0.5811.00
291_P295_K0.5811.00
102_E162_P0.5771.00
27_E30_R0.5761.00
200_N204_A0.5741.00
275_E279_V0.5731.00
209_R212_F0.5731.00
143_E153_N0.5721.00
42_W327_E0.5671.00
209_R219_D0.5671.00
121_Q125_R0.5671.00
234_T240_H0.5671.00
139_E157_Q0.5661.00
254_R275_E0.5631.00
280_N284_S0.5631.00
112_G173_L0.5631.00
143_E147_Y0.5621.00
119_T122_L0.5611.00
99_G160_A0.5591.00
150_P154_V0.5571.00
180_A208_Y0.5551.00
23_G27_E0.5531.00
285_S297_K0.5531.00
159_R164_E0.5500.99
132_N152_G0.5480.99
279_V283_L0.5480.99
209_R306_Q0.5460.99
209_R218_L0.5450.99
99_G148_F0.5430.99
74_T77_I0.5430.99
99_G103_T0.5420.99
125_R130_N0.5410.99
279_V282_Q0.5410.99
210_N213_T0.5380.99
35_L326_F0.5380.99
113_L170_I0.5360.99
220_E308_D0.5340.99
218_L221_P0.5330.99
297_K301_F0.5320.99
84_I94_I0.5300.99
122_L130_N0.5290.99
227_V310_I0.5260.99
102_E168_V0.5250.99
175_S194_A0.5250.99
154_V157_Q0.5240.99
122_L127_L0.5230.99
206_E209_R0.5220.99
68_G71_A0.5220.99
209_R220_E0.5220.99
91_S144_L0.5220.99
110_D309_E0.5210.99
230_I242_A0.5200.99
141_L172_L0.5190.99
257_P261_K0.5180.99
69_H105_Y0.5180.99
245_H248_R0.5180.99
122_L126_A0.5180.99
32_S35_L0.5170.99
208_Y223_A0.5170.99
65_V69_H0.5170.99
281_E284_S0.5160.99
238_A242_A0.5150.99
95_A148_F0.5150.99
105_Y109_I0.5130.99
137_F172_L0.5110.99
65_V104_L0.5110.99
204_A207_L0.5110.99
175_S204_A0.5090.99
63_T81_S0.5070.99
171_W309_E0.5060.99
171_W222_Y0.5060.99
65_V97_Q0.5020.99
228_T313_N0.5000.99
177_G203_P0.5000.99
182_L185_E0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1lucA 1 0.9226 100 0.229 Contact Map
2wgkA 2 0.9702 100 0.242 Contact Map
4us5A 3 0.9583 100 0.248 Contact Map
1lucB 1 0.9196 100 0.248 Contact Map
2i7gA 2 0.9464 100 0.258 Contact Map
1z69A 4 0.9167 100 0.27 Contact Map
3raoA 2 0.9524 100 0.274 Contact Map
1ezwA 3 0.9256 100 0.285 Contact Map
3c8nA 2 0.9405 100 0.291 Contact Map
3b9oA 2 0.9583 100 0.292 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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