YVAQ - BACSU - GREMLIN Contacts

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YVAQ - Putative sensory transducer protein YvaQ

UniProt:	O32239	Sequences: MRLTISRKFSLVFLTLILINLLVGGIGVLNMQHIIQKTDEINTKWIDGIKGITSINYVTEHLSSKEKDFLIYTDKSKMDTLDQEMNQIMEDINQKLDNYEKTISTDKEQKLFEQLQTKVNTYMDIHAQIIESGRTNDMDKARGLLVQTEASFEDMKKTITQLVDLNQEGSNTAVKETKAVYHKGLIYTALLVAASILISIFIWLYITRNIVKPIIRMKESANHIAEGDLSNDMEALNSKDELGDLNEALQKMVGNLRDIVGYSKDISSRVLSSSQVLATATNETRSGSKHITETMNEMAEGSEQQAQDAVTIAESMNEFTESIDKAYNHGITISDTSQNVLELAVSGNENMATSLQQMKTIHHIVEEAVHKVRSLEQHSQDINKLVQVINGIAEQTNLLSLNAAIEAARAGESGKGFAVVAEEVRKLADGVSDSVQDITRIVNGTQQEIHTVITYLESSFTEVEKGTENLTDTGQAMQHIKQSVTHVADSIKEVTDGLKQLTNQSITINQSIENIASVSEESAAGIEETFSITEQSAHSMDQVLLNAEELEQLANELNEKMGQFTI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	566 (528)
Sequences:	20676 (17722)
Seq/√Len:	771.3

ECOLI - MCP3 MCP4 MCP1 MCP2 AER
BACSU - YVAQ YOAH TLPA TLPB MCPC MCPA MCPB TLPC HEMAT
HALSA - HTR4 HTR2 Q9HRA1 Q9HPA2 HTR7 COST Q9HQX8 Q9HS86 Q9HRN6 HMAT Q9HP10 HTR9 Q9HR88 Q9HPQ5 HTR1 Q9HQT5 Q9HPW6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
238_S	243_G	4.660	1.00
223_H	228_D	3.914	1.00
4_T	7_R	3.360	1.00
232_D	257_R	3.110	1.00
137_D	140_K	2.856	1.00
25_G	29_L	2.724	1.00
8_K	240_D	2.680	1.00
250_Q	253_V	2.644	1.00
301_G	518_V	2.626	1.00
223_H	231_N	2.539	1.00
222_N	244_D	2.438	1.00
208_R	212_K	2.407	1.00
186_I	190_L	2.333	1.00
377_Q	380_Q	2.292	1.00
221_A	252_M	2.248	1.00
217_M	246_N	2.241	1.00
343_L	479_H	2.136	1.00
468_E	472_D	2.135	1.00
381_D	384_K	2.120	1.00
218_K	248_A	2.102	1.00
100_E	116_Q	2.095	1.00
218_K	244_D	2.090	1.00
222_N	251_K	2.087	1.00
240_D	243_G	2.083	1.00
222_N	226_E	2.079	1.00
325_K	328_N	2.056	1.00
207_T	211_V	2.053	1.00
361_I	466_G	2.051	1.00
387_Q	391_G	2.042	1.00
378_H	448_E	2.040	1.00
74_D	77_K	2.006	1.00
221_A	249_L	2.005	1.00
224_I	252_M	2.005	1.00
464_E	468_E	2.000	1.00
232_D	254_G	1.991	1.00
342_E	346_S	1.979	1.00
24_G	192_V	1.978	1.00
109_Q	113_E	1.967	1.00
374_S	448_E	1.931	1.00
465_K	468_E	1.926	1.00
183_K	187_Y	1.917	1.00
232_D	250_Q	1.916	1.00
224_I	253_V	1.901	1.00
431_V	435_V	1.891	1.00
461_T	465_K	1.829	1.00
378_H	444_G	1.806	1.00
232_D	253_V	1.801	1.00
507_T	510_Q	1.799	1.00
189_A	193_A	1.792	1.00
486_H	489_D	1.784	1.00
374_S	377_Q	1.778	1.00
244_D	247_E	1.778	1.00
190_L	194_A	1.771	1.00
221_A	248_A	1.768	1.00
471_T	475_Q	1.765	1.00
79_D	83_Q	1.759	1.00
514_N	517_S	1.754	1.00
335_D	339_N	1.748	1.00
250_Q	254_G	1.746	1.00
182_H	186_I	1.746	1.00
355_L	474_G	1.743	1.00
106_D	109_Q	1.740	1.00
372_V	452_V	1.736	1.00
257_R	261_G	1.736	1.00
384_K	387_Q	1.729	1.00
346_S	349_E	1.728	1.00
272_S	276_V	1.720	1.00
339_N	342_E	1.709	1.00
333_I	491_I	1.708	1.00
383_N	446_Q	1.699	1.00
217_M	245_L	1.692	1.00
371_K	452_V	1.684	1.00
373_R	377_Q	1.678	1.00
535_Q	538_H	1.673	1.00
364_I	458_S	1.666	1.00
475_Q	479_H	1.666	1.00
534_E	538_H	1.665	1.00
439_T	443_N	1.658	1.00
376_E	453_I	1.656	1.00
164_D	168_E	1.654	1.00
433_D	437_D	1.648	1.00
222_N	248_A	1.645	1.00
542_Q	545_L	1.643	1.00
86_N	90_E	1.642	1.00
254_G	258_D	1.630	1.00
308_D	514_N	1.618	1.00
426_K	429_D	1.616	1.00
258_D	262_Y	1.611	1.00
347_G	480_I	1.610	1.00
541_D	545_L	1.602	1.00
110_K	114_Q	1.602	1.00
335_D	338_Q	1.593	1.00
8_K	209_N	1.593	1.00
83_Q	87_Q	1.592	1.00
472_D	475_Q	1.590	1.00
377_Q	381_D	1.577	1.00
461_T	464_E	1.570	1.00
16_L	199_S	1.568	1.00
371_K	451_T	1.563	1.00
332_T	335_D	1.559	1.00
6_S	10_S	1.551	1.00
422_E	425_R	1.534	1.00
113_E	117_T	1.521	1.00
6_S	208_R	1.511	1.00
485_T	489_D	1.510	1.00
381_D	437_D	1.503	1.00
370_H	374_S	1.501	1.00
338_Q	342_E	1.501	1.00
344_A	481_K	1.499	1.00
131_E	135_T	1.497	1.00
326_A	498_L	1.495	1.00
367_E	370_H	1.492	1.00
24_G	28_V	1.485	1.00
221_A	245_L	1.484	1.00
370_H	373_R	1.481	1.00
345_V	349_E	1.480	1.00
479_H	482_Q	1.462	1.00
107_K	110_K	1.462	1.00
404_A	422_E	1.461	1.00
185_L	189_A	1.459	1.00
27_G	188_T	1.440	1.00
175_K	179_A	1.437	1.00
82_D	86_N	1.435	1.00
524_A	528_E	1.432	1.00
161_Q	164_D	1.430	1.00
331_I	335_D	1.428	1.00
475_Q	478_Q	1.425	1.00
168_E	172_T	1.414	1.00
217_M	249_L	1.412	1.00
429_D	433_D	1.407	1.00
228_D	231_N	1.402	1.00
311_T	314_E	1.399	1.00
366_E	370_H	1.396	1.00
264_K	268_S	1.394	1.00
182_H	185_L	1.390	1.00
203_W	207_T	1.387	1.00
105_T	108_E	1.384	1.00
478_Q	482_Q	1.378	1.00
297_E	300_E	1.376	1.00
272_S	275_Q	1.373	1.00
125_I	128_Q	1.372	1.00
524_A	527_E	1.367	1.00
120_N	124_D	1.366	1.00
154_D	157_K	1.366	1.00
457_E	461_T	1.366	1.00
317_N	321_E	1.365	1.00
353_T	356_Q	1.365	1.00
352_A	356_Q	1.359	1.00
372_V	456_L	1.358	1.00
345_V	485_T	1.357	1.00
75_K	79_D	1.356	1.00
538_H	542_Q	1.356	1.00
236_L	250_Q	1.346	1.00
390_N	439_T	1.343	1.00
506_I	510_Q	1.342	1.00
450_H	454_T	1.338	1.00
171_N	175_K	1.335	1.00
499_K	503_N	1.332	1.00
324_D	328_N	1.326	1.00
349_E	353_T	1.323	1.00
436_Q	440_R	1.322	1.00
265_D	268_S	1.319	1.00
114_Q	118_K	1.314	1.00
219_E	222_N	1.312	1.00
253_V	257_R	1.309	1.00
67_K	71_I	1.307	1.00
363_H	367_E	1.306	1.00
528_E	531_S	1.300	1.00
116_Q	120_N	1.296	1.00
216_R	234_E	1.290	1.00
378_H	381_D	1.289	1.00
234_E	237_N	1.283	1.00
404_A	425_R	1.280	1.00
276_V	279_T	1.277	1.00
215_I	218_K	1.272	1.00
113_E	116_Q	1.269	1.00
517_S	521_E	1.267	1.00
360_T	462_E	1.266	1.00
433_D	436_Q	1.265	1.00
160_T	164_D	1.263	1.00
39_D	43_T	1.263	1.00
331_I	499_K	1.258	1.00
379_S	449_I	1.258	1.00
4_T	244_D	1.257	1.00
63_S	67_K	1.255	1.00
76_S	79_D	1.255	1.00
296_N	300_E	1.253	1.00
28_V	32_Q	1.248	1.00
22_L	26_I	1.248	1.00
307_Q	310_V	1.244	1.00
268_S	272_S	1.242	1.00
108_E	111_L	1.237	1.00
119_V	123_M	1.236	1.00
458_S	461_T	1.235	1.00
181_Y	185_L	1.230	1.00
454_T	457_E	1.229	1.00
350_N	472_D	1.229	1.00
319_F	505_S	1.228	1.00
348_N	478_Q	1.227	1.00
328_N	332_T	1.224	1.00
342_E	345_V	1.218	1.00
162_L	166_N	1.215	1.00
151_S	154_D	1.207	1.00
187_Y	190_L	1.206	1.00
304_Q	307_Q	1.203	1.00
363_H	366_E	1.201	1.00
353_T	469_N	1.195	1.00
87_Q	90_E	1.195	1.00
390_N	435_V	1.193	1.00
106_D	110_K	1.187	1.00
513_E	517_S	1.187	1.00
88_I	91_D	1.185	1.00
161_Q	165_L	1.184	1.00
186_I	189_A	1.184	1.00
358_M	466_G	1.183	1.00
477_M	480_I	1.182	1.00
157_K	161_Q	1.179	1.00
262_Y	265_D	1.177	1.00
226_E	251_K	1.177	1.00
496_D	499_K	1.176	1.00
300_E	304_Q	1.173	1.00
5_I	242_L	1.172	1.00
307_Q	311_T	1.171	1.00
372_V	453_I	1.171	1.00
58_V	62_L	1.168	1.00
262_Y	542_Q	1.166	1.00
324_D	506_I	1.165	1.00
217_M	221_A	1.163	1.00
77_K	80_T	1.163	1.00
6_S	207_T	1.161	1.00
220_S	233_M	1.160	1.00
364_I	462_E	1.158	1.00
388_V	434_S	1.153	1.00
236_L	246_N	1.151	1.00
265_D	269_R	1.150	1.00
255_N	258_D	1.142	1.00
29_L	33_H	1.140	1.00
218_K	222_N	1.139	1.00
496_D	500_Q	1.133	1.00
277_L	281_T	1.133	1.00
347_G	477_M	1.131	1.00
357_Q	465_K	1.129	1.00
174_V	178_K	1.129	1.00
35_I	181_Y	1.128	1.00
401_L	409_R	1.127	1.00
117_T	121_T	1.124	1.00
354_S	473_T	1.119	1.00
147_Q	150_A	1.116	1.00
482_Q	486_H	1.114	1.00
305_Q	309_A	1.112	1.00
356_Q	360_T	1.112	1.00
275_Q	279_T	1.112	1.00
348_N	481_K	1.108	1.00
131_E	134_R	1.106	1.00
57_Y	60_E	1.106	1.00
359_K	363_H	1.104	1.00
166_N	169_G	1.102	1.00
124_D	127_A	1.102	1.00
346_S	479_H	1.098	1.00
200_I	204_L	1.097	1.00
160_T	163_V	1.097	1.00
341_L	345_V	1.097	1.00
223_H	226_E	1.090	1.00
521_E	524_A	1.089	1.00
56_N	60_E	1.089	1.00
213_P	241_E	1.088	1.00
26_I	30_N	1.083	1.00
233_M	250_Q	1.082	1.00
300_E	303_E	1.078	1.00
365_V	463_V	1.077	1.00
346_S	472_D	1.077	1.00
216_R	219_E	1.070	1.00
48_G	52_I	1.068	1.00
246_N	250_Q	1.068	1.00
302_S	309_A	1.067	1.00
531_S	535_Q	1.063	1.00
69_F	133_G	1.060	1.00
309_A	515_I	1.058	1.00
236_L	240_D	1.058	1.00
271_L	275_Q	1.056	1.00
140_K	143_G	1.056	1.00
111_L	114_Q	1.052	1.00
229_L	256_L	1.050	1.00
114_Q	117_T	1.046	1.00
80_T	83_Q	1.043	1.00
173_A	176_E	1.043	1.00
373_R	457_E	1.039	1.00
64_S	68_D	1.038	1.00
215_I	219_E	1.035	1.00
527_E	531_S	1.033	1.00
318_E	321_E	1.033	1.00
314_E	318_E	1.032	1.00
385_L	441_I	1.031	1.00
258_D	261_G	1.031	1.00
149_E	153_E	1.030	1.00
341_L	488_A	1.029	1.00
328_N	331_I	1.028	1.00
153_E	157_K	1.026	1.00
172_T	176_E	1.024	1.00
229_L	260_V	1.018	1.00
19_I	195_S	1.017	1.00
249_L	252_M	1.016	1.00
303_E	307_Q	1.016	1.00
371_K	455_Y	1.014	1.00
87_Q	91_D	1.014	1.00
538_H	541_D	1.014	1.00
218_K	245_L	1.014	1.00
261_G	265_D	1.011	1.00
148_T	152_F	1.008	1.00
468_E	471_T	1.007	1.00
362_H	467_T	1.007	1.00
158_T	161_Q	1.005	1.00
128_Q	131_E	1.004	1.00
500_Q	503_N	1.002	1.00
436_Q	439_T	0.998	1.00
126_H	130_I	0.995	1.00
233_M	246_N	0.994	1.00
359_K	471_T	0.987	1.00
107_K	111_L	0.983	1.00
375_L	445_T	0.983	1.00
119_V	122_Y	0.982	1.00
123_M	127_A	0.981	1.00
204_L	208_R	0.980	1.00
128_Q	147_Q	0.975	1.00
60_E	63_S	0.973	1.00
10_S	14_L	0.973	1.00
510_Q	514_N	0.970	1.00
214_I	245_L	0.969	1.00
376_E	380_Q	0.969	1.00
76_S	80_T	0.966	1.00
340_V	484_V	0.965	1.00
437_D	440_R	0.963	1.00
368_A	455_Y	0.962	1.00
220_S	249_L	0.961	1.00
361_I	463_V	0.956	1.00
98_N	101_K	0.955	1.00
201_F	205_Y	0.951	1.00
86_N	89_M	0.942	1.00
223_H	252_M	0.941	1.00
30_N	33_H	0.939	1.00
321_E	325_K	0.939	1.00
51_G	54_S	0.938	1.00
251_K	254_G	0.934	1.00
13_F	203_W	0.933	1.00
138_M	142_R	0.931	1.00
193_A	197_L	0.930	1.00
247_E	250_Q	0.928	1.00
312_I	508_I	0.926	1.00
212_K	216_R	0.926	1.00
84_E	87_Q	0.925	1.00
343_L	483_S	0.925	1.00
213_P	238_S	0.924	1.00
17_I	199_S	0.923	1.00
147_Q	151_S	0.919	1.00
234_E	250_Q	0.916	1.00
517_S	520_E	0.915	1.00
356_Q	359_K	0.913	1.00
124_D	128_Q	0.912	1.00
158_T	162_L	0.909	1.00
239_K	243_G	0.908	1.00
179_A	183_K	0.907	1.00
126_H	129_I	0.906	1.00
127_A	131_E	0.905	1.00
310_V	314_E	0.905	1.00
443_N	447_Q	0.905	1.00
547_A	550_L	0.904	1.00
209_N	213_P	0.904	1.00
160_T	167_Q	0.904	1.00
520_E	524_A	0.895	1.00
142_R	146_V	0.890	1.00
81_L	85_M	0.890	1.00
69_F	73_T	0.889	1.00
298_M	302_S	0.889	1.00
213_P	242_L	0.888	1.00
336_T	486_H	0.888	1.00
348_N	352_A	0.882	1.00
224_I	249_L	0.882	1.00
236_L	247_E	0.881	1.00
23_V	27_G	0.881	1.00
12_V	19_I	0.881	1.00
13_F	16_L	0.881	1.00
422_E	426_K	0.880	1.00
121_T	124_D	0.878	1.00
242_L	246_N	0.878	1.00
219_E	223_H	0.877	1.00
489_D	493_E	0.875	1.00
493_E	496_D	0.874	1.00
432_S	436_Q	0.869	1.00
259_I	263_S	0.868	1.00
297_E	521_E	0.864	1.00
143_G	146_V	0.863	1.00
263_S	266_I	0.863	1.00
305_Q	519_S	0.863	1.00
178_K	182_H	0.862	1.00
390_N	394_E	0.859	1.00
220_S	231_N	0.859	1.00
316_M	512_I	0.859	1.00
79_D	82_D	0.858	1.00
20_N	23_V	0.857	1.00
454_T	458_S	0.857	1.00
48_G	51_G	0.856	1.00
320_T	509_N	0.855	1.00
430_G	433_D	0.851	1.00
136_N	139_D	0.851	1.00
62_L	65_K	0.848	1.00
12_V	16_L	0.848	1.00
373_R	376_E	0.847	1.00
360_T	363_H	0.847	1.00
329_H	493_E	0.842	1.00
325_K	493_E	0.841	1.00
312_I	512_I	0.841	1.00
462_E	465_K	0.840	1.00
104_S	108_E	0.839	1.00
163_V	167_Q	0.838	1.00
503_N	507_T	0.836	1.00
312_I	511_S	0.836	1.00
167_Q	171_N	0.836	1.00
251_K	255_N	0.834	1.00
430_G	437_D	0.834	1.00
369_V	460_F	0.833	1.00
214_I	242_L	0.832	1.00
317_N	509_N	0.830	1.00
27_G	31_M	0.828	1.00
546_N	549_E	0.827	1.00
341_L	485_T	0.825	1.00
139_D	143_G	0.824	1.00
262_Y	266_I	0.822	1.00
304_Q	514_N	0.818	1.00
148_T	151_S	0.817	1.00
489_D	492_K	0.815	1.00
366_E	460_F	0.812	1.00
82_D	89_M	0.809	1.00
216_R	220_S	0.806	1.00
85_M	89_M	0.805	1.00
391_G	394_E	0.805	1.00
249_L	253_V	0.805	1.00
105_T	109_Q	0.803	1.00
510_Q	513_E	0.802	1.00
376_E	450_H	0.802	1.00
261_G	264_K	0.800	1.00
231_N	253_V	0.794	1.00
6_S	211_V	0.794	1.00
385_L	442_V	0.792	1.00
349_E	352_A	0.790	1.00
299_A	303_E	0.788	1.00
65_K	68_D	0.788	1.00
220_S	223_H	0.787	1.00
47_D	51_G	0.787	1.00
139_D	142_R	0.786	1.00
118_K	121_T	0.784	1.00
492_K	496_D	0.784	1.00
447_Q	451_T	0.783	1.00
110_K	113_E	0.783	1.00
319_F	501_L	0.782	1.00
221_A	224_I	0.781	1.00
205_Y	208_R	0.777	1.00
127_A	130_I	0.775	1.00
351_M	470_L	0.774	1.00
531_S	534_E	0.772	1.00
142_R	145_L	0.772	1.00
152_F	155_M	0.770	1.00
187_Y	191_L	0.769	1.00
197_L	201_F	0.769	1.00
374_S	378_H	0.768	1.00
78_M	82_D	0.767	1.00
391_G	430_G	0.767	1.00
5_I	214_I	0.767	1.00
375_L	452_V	0.766	1.00
384_K	388_V	0.766	1.00
68_D	71_I	0.766	1.00
339_N	483_S	0.765	1.00
351_M	473_T	0.759	1.00
17_I	203_W	0.757	1.00
263_S	267_S	0.756	1.00
269_R	272_S	0.756	1.00
207_T	210_I	0.755	1.00
440_R	443_N	0.754	1.00
364_I	367_E	0.754	1.00
183_K	186_I	0.751	1.00
260_V	263_S	0.750	1.00
446_Q	450_H	0.749	1.00
68_D	72_Y	0.748	1.00
227_G	252_M	0.748	1.00
323_I	498_L	0.748	1.00
368_A	456_L	0.747	1.00
358_M	361_I	0.747	1.00
380_Q	450_H	0.747	1.00
211_V	215_I	0.745	1.00
469_N	472_D	0.744	1.00
369_V	457_E	0.743	1.00
379_S	445_T	0.742	1.00
343_L	346_S	0.741	1.00
80_T	84_E	0.741	1.00
529_T	532_I	0.740	1.00
368_A	459_S	0.739	1.00
381_D	441_I	0.739	1.00
121_T	125_I	0.738	1.00
277_L	280_A	0.738	1.00
40_E	44_K	0.737	1.00
28_V	185_L	0.736	1.00
168_E	173_A	0.736	1.00
365_V	456_L	0.736	1.00
318_E	504_Q	0.735	1.00
100_E	113_E	0.735	1.00
353_T	472_D	0.735	1.00
543_V	550_L	0.734	1.00
165_L	168_E	0.732	1.00
210_I	213_P	0.732	1.00
536_S	550_L	0.731	1.00
304_Q	308_D	0.731	1.00
152_F	156_K	0.731	1.00
140_K	144_L	0.731	1.00
117_T	120_N	0.730	1.00
268_S	271_L	0.728	1.00
215_I	244_D	0.728	1.00
26_I	29_L	0.727	1.00
32_Q	36_Q	0.727	1.00
111_L	115_L	0.726	1.00
29_L	32_Q	0.726	1.00
332_T	490_S	0.726	1.00
212_K	215_I	0.725	1.00
5_I	241_E	0.724	1.00
30_N	184_G	0.723	1.00
83_Q	86_N	0.721	1.00
379_S	385_L	0.721	1.00
46_I	49_I	0.720	1.00
321_E	324_D	0.719	1.00
344_A	347_G	0.719	1.00
60_E	64_S	0.717	1.00
366_E	464_E	0.715	1.00
150_A	154_D	0.714	1.00
148_T	154_D	0.713	1.00
449_I	452_V	0.713	1.00
62_L	66_E	0.712	1.00
47_D	50_K	0.711	1.00
32_Q	185_L	0.708	1.00
42_N	47_D	0.706	1.00
308_D	511_S	0.706	1.00
169_G	172_T	0.704	1.00
273_S	277_L	0.704	1.00
449_I	453_I	0.702	1.00
225_A	251_K	0.697	1.00
369_V	456_L	0.696	1.00
397_N	425_R	0.694	1.00
52_I	55_I	0.690	1.00
534_E	537_A	0.690	1.00
31_M	35_I	0.689	1.00
494_V	497_G	0.689	1.00
252_M	256_L	0.688	1.00
59_T	62_L	0.688	1.00
42_N	45_W	0.684	1.00
545_L	548_E	0.684	1.00
153_E	156_K	0.683	1.00
141_A	146_V	0.680	1.00
75_K	78_M	0.680	1.00
365_V	459_S	0.679	1.00
116_Q	119_V	0.676	1.00
320_T	505_S	0.676	1.00
259_I	262_Y	0.675	1.00
334_S	338_Q	0.674	1.00
536_S	540_M	0.672	1.00
338_Q	492_K	0.672	1.00
266_I	269_R	0.670	1.00
82_D	134_R	0.668	1.00
365_V	368_A	0.666	1.00
386_V	390_N	0.662	1.00
115_L	119_V	0.662	1.00
375_L	385_L	0.661	1.00
141_A	145_L	0.661	1.00
394_E	405_I	0.660	1.00
330_G	498_L	0.660	1.00
27_G	30_N	0.659	1.00
380_Q	384_K	0.656	1.00
209_N	212_K	0.654	1.00
255_N	549_E	0.653	1.00
70_L	73_T	0.652	1.00
539_S	542_Q	0.651	1.00
123_M	129_I	0.650	1.00
236_L	243_G	0.650	1.00
428_A	431_V	0.650	1.00
451_T	454_T	0.649	1.00
22_L	25_G	0.649	1.00
440_R	444_G	0.646	1.00
353_T	465_K	0.646	1.00
241_E	244_D	0.646	1.00
458_S	462_E	0.645	1.00
166_N	173_A	0.645	1.00
61_H	64_S	0.644	1.00
516_A	520_E	0.642	1.00
544_L	548_E	0.642	1.00
58_V	61_H	0.641	1.00
313_A	318_E	0.641	1.00
220_S	224_I	0.641	1.00
163_V	166_N	0.639	1.00
350_N	476_A	0.637	1.00
506_I	509_N	0.636	1.00
537_A	541_D	0.636	1.00
41_I	44_K	0.635	1.00
67_K	72_Y	0.635	1.00
141_A	144_L	0.634	1.00
270_V	273_S	0.633	1.00
500_Q	504_Q	0.632	1.00
170_S	173_A	0.632	1.00
89_M	92_I	0.632	1.00
118_K	158_T	0.631	1.00
177_T	181_Y	0.631	1.00
66_E	70_L	0.630	1.00
225_A	248_A	0.629	1.00
64_S	67_K	0.628	1.00
323_I	505_S	0.626	1.00
69_F	82_D	0.625	1.00
329_H	490_S	0.625	1.00
168_E	171_N	0.625	1.00
301_G	522_S	0.624	1.00
48_G	166_N	0.624	1.00
357_Q	469_N	0.623	1.00
344_A	348_N	0.623	1.00
199_S	203_W	0.622	1.00
425_R	429_D	0.622	1.00
89_M	93_N	0.621	1.00
37_K	40_E	0.621	1.00
149_E	154_D	0.620	1.00
400_S	425_R	0.620	1.00
50_K	53_T	0.620	1.00
270_V	274_S	0.619	1.00
175_K	178_K	0.617	1.00
122_Y	125_I	0.617	1.00
340_V	483_S	0.616	1.00
299_A	523_A	0.616	1.00
33_H	37_K	0.616	1.00
337_S	484_V	0.615	1.00
354_S	470_L	0.615	1.00
57_Y	61_H	0.612	1.00
297_E	301_G	0.611	1.00
176_E	180_V	0.611	1.00
518_V	522_S	0.610	1.00
337_S	487_V	0.609	1.00
267_S	274_S	0.606	1.00
263_S	270_V	0.605	1.00
10_S	207_T	0.605	1.00
532_I	535_Q	0.603	1.00
38_T	41_I	0.603	1.00
31_M	34_I	0.602	1.00
100_E	109_Q	0.601	1.00
381_D	444_G	0.598	1.00
109_Q	112_F	0.597	1.00
49_I	53_T	0.597	1.00
447_Q	450_H	0.596	1.00
521_E	525_G	0.596	1.00
213_P	240_D	0.594	1.00
44_K	48_G	0.593	1.00
143_G	147_Q	0.592	1.00
482_Q	485_T	0.591	1.00
98_N	102_T	0.590	1.00
122_Y	126_H	0.589	1.00
386_V	439_T	0.588	1.00
367_E	455_Y	0.586	1.00
543_V	547_A	0.585	1.00
486_H	490_S	0.583	1.00
122_Y	129_I	0.583	1.00
507_T	511_S	0.582	1.00
350_N	473_T	0.582	1.00
384_K	437_D	0.582	1.00
317_N	320_T	0.580	1.00
452_V	456_L	0.580	1.00
374_S	451_T	0.578	1.00
125_I	129_I	0.578	1.00
123_M	126_H	0.576	1.00
481_K	485_T	0.576	1.00
315_S	504_Q	0.576	1.00
118_K	122_Y	0.575	1.00
7_R	10_S	0.575	1.00
85_M	92_I	0.574	1.00
385_L	388_V	0.573	1.00
350_N	469_N	0.572	1.00
238_S	241_E	0.571	1.00
332_T	486_H	0.571	1.00
24_G	27_G	0.568	1.00
20_N	27_G	0.568	1.00
362_H	464_E	0.567	1.00
130_I	134_R	0.566	1.00
385_L	434_S	0.565	1.00
334_S	492_K	0.564	1.00
16_L	20_N	0.564	1.00
267_S	270_V	0.563	1.00
314_E	317_N	0.563	1.00
9_F	13_F	0.562	1.00
155_M	158_T	0.562	1.00
360_T	364_I	0.562	1.00
460_F	464_E	0.561	1.00
315_S	318_E	0.561	1.00
474_G	478_Q	0.560	1.00
53_T	56_N	0.560	1.00
218_K	242_L	0.559	1.00
46_I	170_S	0.559	1.00
333_I	490_S	0.559	1.00
540_M	550_L	0.559	1.00
211_V	242_L	0.559	1.00
327_Y	495_T	0.558	1.00
35_I	38_T	0.557	1.00
50_K	54_S	0.557	1.00
313_A	512_I	0.557	1.00
66_E	126_H	0.556	1.00
51_G	98_N	0.556	1.00
99_Y	103_I	0.556	1.00
66_E	69_F	0.555	1.00
395_Q	423_E	0.554	1.00
390_N	436_Q	0.554	1.00
224_I	256_L	0.553	1.00
473_T	476_A	0.553	1.00
45_W	169_G	0.551	1.00
162_L	168_E	0.551	1.00
471_T	474_G	0.550	1.00
54_S	57_Y	0.550	1.00
35_I	39_D	0.550	1.00
12_V	199_S	0.549	1.00
147_Q	154_D	0.549	1.00
53_T	57_Y	0.549	1.00
190_L	193_A	0.549	1.00
431_V	441_I	0.548	1.00
32_Q	35_I	0.547	1.00
360_T	465_K	0.545	1.00
27_G	32_Q	0.544	1.00
299_A	302_S	0.543	1.00
495_T	498_L	0.543	1.00
38_T	177_T	0.541	1.00
385_L	431_V	0.540	1.00
382_I	442_V	0.540	1.00
34_I	37_K	0.539	1.00
240_D	246_N	0.538	1.00
158_T	164_D	0.536	1.00
524_A	531_S	0.535	1.00
155_M	159_I	0.535	1.00
394_E	432_S	0.534	1.00
525_G	528_E	0.534	1.00
34_I	38_T	0.534	1.00
278_A	281_T	0.534	1.00
463_V	466_G	0.533	1.00
28_V	181_Y	0.533	1.00
217_M	242_L	0.531	1.00
7_R	11_L	0.531	1.00
72_Y	77_K	0.531	1.00
36_Q	39_D	0.531	1.00
226_E	255_N	0.529	1.00
169_G	173_A	0.529	1.00
268_S	544_L	0.528	1.00
305_Q	518_V	0.527	1.00
327_Y	330_G	0.527	1.00
357_Q	462_E	0.526	1.00
104_S	109_Q	0.525	1.00
308_D	311_T	0.525	1.00
358_M	470_L	0.524	1.00
69_F	72_Y	0.524	1.00
154_D	158_T	0.524	1.00
318_E	500_Q	0.524	1.00
503_N	506_I	0.524	1.00
375_L	466_G	0.523	1.00
149_E	152_F	0.522	1.00
151_S	157_K	0.521	1.00
306_A	520_E	0.521	1.00
140_K	146_V	0.520	1.00
310_V	516_A	0.520	1.00
44_K	49_I	0.520	1.00
54_S	58_V	0.519	1.00
93_N	123_M	0.519	1.00
88_I	92_I	0.519	1.00
529_T	536_S	0.519	1.00
194_A	201_F	0.517	1.00
119_V	125_I	0.517	1.00
444_G	448_E	0.516	1.00
297_E	525_G	0.516	1.00
164_D	167_Q	0.514	1.00
339_N	343_L	0.514	1.00
148_T	155_M	0.514	1.00
5_I	210_I	0.513	1.00
340_V	487_V	0.512	1.00
59_T	63_S	0.512	1.00
323_I	501_L	0.512	1.00
162_L	165_L	0.511	1.00
31_M	184_G	0.511	1.00
539_S	543_V	0.510	1.00
330_G	333_I	0.510	1.00
38_T	42_N	0.509	1.00
523_A	526_I	0.509	1.00
387_Q	390_N	0.508	1.00
194_A	198_I	0.505	1.00
180_V	184_G	0.505	1.00
533_T	537_A	0.504	1.00
318_E	322_S	0.504	1.00
39_D	42_N	0.503	1.00
267_S	271_L	0.501	1.00
252_M	255_N	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zx6A	2	0.5371	100	0.413	Contact Map
2ch7A	2	0.5459	100	0.507	Contact Map
1qu7A	2	0.4011	100	0.539	Contact Map
3g67A	2	0.3693	100	0.605	Contact Map
4i3mA	2	0.2597	99.9	0.752	Contact Map
4cq4A	4	0.1537	99.5	0.841	Contact Map
2f95B	2	0.0919	99.4	0.849	Contact Map
4gycB	2	0.106	99.2	0.861	Contact Map
3zccA	2	0.1926	98.9	0.881	Contact Map
4i5sA	2	0.5406	98.6	0.891	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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