GREMLIN Database
RNR - Ribonuclease R
UniProt: O32231 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 779 (681)
Sequences: 3633 (2227)
Seq/√Len: 85.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
249_R357_E4.9471.00
348_N352_Q4.8731.00
337_D364_K4.5451.00
632_D690_T4.4831.00
232_Q299_P4.1271.00
183_K197_E4.0541.00
96_V127_G3.9441.00
262_A372_S3.7961.00
252_R337_D3.7131.00
274_T282_K3.5601.00
278_D346_T3.5381.00
630_E690_T3.3301.00
226_P229_A3.3201.00
254_Q274_T3.1631.00
227_A231_E3.0251.00
280_S346_T2.9541.00
340_T363_I2.9361.00
471_I597_A2.8311.00
111_I134_E2.8211.00
286_H342_S2.8121.00
453_L550_T2.7981.00
256_I363_I2.6061.00
96_V114_V2.6051.00
554_T568_V2.5991.00
144_Y151_G2.5911.00
360_Q573_R2.5761.00
74_G86_L2.5741.00
99_P102_E2.5091.00
375_N379_V2.5091.00
144_Y171_K2.5041.00
295_T298_S2.4871.00
633_G645_V2.4401.00
692_K706_E2.4041.00
113_M131_R2.3931.00
249_R359_F2.3781.00
635_I683_F2.3621.00
89_E111_I2.3591.00
344_E359_F2.3581.00
115_R128_T2.3431.00
271_V448_I2.3291.00
282_K344_E2.3241.00
241_D244_D2.3231.00
375_N442_S2.3201.00
76_I103_L2.3081.00
256_I366_T2.3021.00
386_K397_K2.2371.00
311_V607_A2.2021.00
333_N336_V2.1911.00
64_G69_M2.1801.00
428_D432_A2.1701.00
643_M655_V2.1681.00
309_T603_M2.1621.00
474_I539_D2.1611.00
632_D688_E2.1541.00
689_I707_I2.1541.00
200_T217_H2.1531.00
142_G153_V2.1521.00
305_L596_I2.1491.00
291_S566_L2.1471.00
263_D424_K2.1301.00
340_T361_S2.0911.00
308_G603_M2.0791.00
476_E543_L2.0711.00
178_H204_H2.0701.00
276_L280_S2.0631.00
346_T355_E2.0551.00
244_D247_D2.0491.00
474_I543_L2.0481.00
360_Q577_I2.0411.00
73_K111_I2.0331.00
284_G344_E2.0281.00
490_V525_I2.0281.00
408_D412_D2.0071.00
471_I567_I1.9811.00
457_E550_T1.9781.00
342_S361_S1.9741.00
251_L344_E1.9711.00
229_A303_E1.9591.00
666_R677_E1.9571.00
226_P303_E1.9511.00
86_L98_I1.9401.00
694_V706_E1.8981.00
662_D665_Y1.8861.00
347_I454_V1.8851.00
156_D179_K1.8801.00
255_V395_M1.8771.00
167_P170_G1.8771.00
305_L599_H1.8431.00
655_V689_I1.8421.00
518_D522_E1.8401.00
234_S324_R1.8341.00
238_D324_R1.8311.00
641_F654_L1.8281.00
630_E692_K1.8011.00
309_T564_P1.8011.00
564_P600_T1.7951.00
233_A324_R1.7841.00
598_E602_S1.7761.00
267_L368_R1.7751.00
641_F644_F1.7701.00
342_S359_F1.7591.00
404_Q443_V1.7511.00
139_R183_K1.7461.00
626_K629_E1.7451.00
275_K401_R1.7371.00
663_D676_G1.7371.00
603_M606_R1.7341.00
373_D385_L1.7321.00
347_I353_V1.7301.00
400_E404_Q1.7101.00
314_V614_T1.7011.00
256_I340_T1.6921.00
284_G342_S1.6851.00
276_L279_G1.6841.00
442_S445_E1.6781.00
286_H361_S1.6781.00
111_I133_L1.6691.00
73_K113_M1.6641.00
164_I196_G1.6611.00
471_I600_T1.6611.00
276_L282_K1.6611.00
486_F529_M1.6561.00
77_S87_L1.6461.00
182_V196_G1.6451.00
657_V674_M1.6271.00
618_K621_E1.6221.00
273_V398_D1.6221.00
255_V366_T1.6191.00
272_T286_H1.6121.00
232_Q298_S1.6011.00
635_I643_M1.6001.00
264_A267_L1.6001.00
245_L252_R1.6001.00
185_T197_E1.5931.00
251_L361_S1.5741.00
334_P365_T1.5731.00
620_A696_V1.5711.00
275_K398_D1.5521.00
280_S349_S1.5521.00
170_G197_E1.5461.00
27_L42_L1.5411.00
259_I447_L1.5311.00
373_D388_K1.5301.00
486_F490_V1.5301.00
49_L54_L1.5281.00
377_I393_V1.5271.00
648_P688_E1.5191.00
273_V399_M1.5111.00
428_D434_K1.5091.00
352_Q409_K1.5071.00
140_V182_V1.5010.99
114_V129_V1.5010.99
426_L437_V1.4890.99
400_E403_A1.4850.99
514_D517_R1.4840.99
301_D563_Y1.4830.99
86_L114_V1.4810.99
88_P91_T1.4760.99
335_K364_K1.4690.99
245_L362_V1.4620.99
282_K346_T1.4530.99
301_D570_R1.4480.99
624_L698_K1.4370.99
280_S354_T1.4360.99
257_V395_M1.4330.99
407_R450_E1.4310.99
356_H462_H1.4290.99
236_T329_I1.4270.99
33_I42_L1.4250.99
407_R446_K1.4220.99
432_A621_E1.4220.99
353_V458_T1.4210.99
426_L435_D1.4150.99
528_V672_F1.4080.99
179_K214_S1.4010.99
345_M458_T1.3990.99
535_Q605_R1.3940.99
328_G333_N1.3900.99
346_T354_T1.3900.99
75_K111_I1.3890.99
696_V703_I1.3880.99
281_Y398_D1.3840.99
46_L63_Y1.3780.99
341_L573_R1.3770.99
385_L389_Y1.3760.99
476_E537_K1.3750.99
276_L346_T1.3610.99
323_H327_N1.3600.99
668_D671_H1.3600.99
138_Q183_K1.3450.99
285_V345_M1.3410.99
630_E708_V1.3370.99
271_V399_M1.3360.99
187_Y194_A1.3300.99
308_G600_T1.3210.99
298_S302_K1.3190.99
341_L572_I1.3170.99
341_L360_Q1.3150.99
516_V525_I1.3150.99
261_G374_V1.3110.99
356_H458_T1.3070.99
272_T284_G1.3040.99
599_H603_M1.2990.99
152_F163_D1.2980.98
86_L112_V1.2930.98
398_D401_R1.2890.98
358_I458_T1.2880.98
215_V617_L1.2830.98
643_M660_M1.2820.98
343_C458_T1.2800.98
367_E388_K1.2790.98
343_C358_I1.2780.98
144_Y153_V1.2720.98
407_R411_M1.2690.98
85_F95_D1.2670.98
642_G654_L1.2660.98
256_I286_H1.2650.98
653_G705_F1.2630.98
76_I84_A1.2620.98
216_I318_I1.2610.98
275_K349_S1.2590.98
375_N445_E1.2580.98
387_Q390_E1.2540.98
219_H613_E1.2530.98
479_N534_K1.2530.98
153_V182_V1.2490.98
400_E443_V1.2450.98
554_T571_L1.2450.98
232_Q295_T1.2420.98
689_I708_V1.2370.98
153_V198_V1.2340.98
373_D389_Y1.2330.98
303_E306_E1.2310.98
378_L397_K1.2290.98
495_Y521_E1.2250.98
309_T607_A1.2240.98
399_M451_F1.2160.98
353_V454_V1.2140.98
393_V397_K1.2120.98
78_A103_L1.2110.98
573_R577_I1.2100.98
673_A682_V1.2070.98
278_D354_T1.2060.98
252_R362_V1.2040.98
28_E39_F1.1950.97
638_V643_M1.1940.97
656_H659_F1.1940.97
153_V180_V1.1930.97
106_A129_V1.1920.97
620_A703_I1.1860.97
665_Y676_G1.1850.97
181_V200_T1.1840.97
231_E234_S1.1830.97
462_H466_M1.1820.97
339_L362_V1.1810.97
112_V129_V1.1810.97
594_P598_E1.1770.97
40_K43_V1.1730.97
490_V495_Y1.1730.97
665_Y681_N1.1680.97
369_M392_L1.1650.97
157_D218_K1.1650.97
90_D93_L1.1630.97
695_D704_D1.1600.97
281_Y405_I1.1600.97
273_V395_M1.1590.97
84_A129_V1.1580.97
403_A450_E1.1580.97
511_S515_A1.1560.97
311_V610_A1.1550.97
378_L400_E1.1550.97
221_L610_A1.1540.97
348_N354_T1.1510.97
153_V196_G1.1490.97
423_A650_T1.1450.97
490_V512_I1.1440.97
370_T373_D1.1280.96
50_E57_R1.1270.96
377_I396_F1.1250.96
563_Y570_R1.1240.96
540_P597_A1.1230.96
272_T342_S1.1230.96
276_L354_T1.1220.96
183_K199_E1.1220.96
634_M648_P1.1200.96
691_V705_F1.1190.96
75_K87_L1.1150.96
113_M133_L1.1150.96
152_F165_F1.1140.96
257_V369_M1.1100.96
139_R199_E1.1080.96
272_T366_T1.1080.96
218_K613_E1.1070.96
79_H82_G1.1000.96
222_P606_R1.1000.96
178_H201_I1.1000.96
693_V703_I1.0970.96
324_R329_I1.0960.96
410_R450_E1.0950.96
249_R344_E1.0930.96
24_V43_V1.0900.96
57_R61_D1.0890.96
256_I271_V1.0870.95
87_L95_D1.0870.95
211_D618_K1.0850.95
242_E245_L1.0840.95
443_V447_L1.0780.95
58_T62_R1.0780.95
164_I182_V1.0760.95
262_A373_D1.0700.95
309_T600_T1.0680.95
145_T154_I1.0640.95
655_V659_F1.0610.95
221_L318_I1.0600.95
251_L256_I1.0570.95
632_D648_P1.0560.95
43_V47_V1.0560.95
204_H207_D1.0520.95
645_V655_V1.0510.95
692_K708_V1.0500.95
215_V610_A1.0500.95
633_G647_L1.0480.94
256_I272_T1.0480.94
233_A298_S1.0470.94
571_L575_Y1.0460.94
369_M396_F1.0450.94
114_V127_G1.0440.94
464_H552_F1.0400.94
377_I389_Y1.0400.94
392_L396_F1.0360.94
71_L113_M1.0330.94
72_I114_V1.0270.94
182_V198_V1.0260.94
592_R596_I1.0250.94
664_Y677_E1.0220.94
696_V699_D1.0210.94
516_V526_S1.0200.94
463_F568_V1.0180.94
229_A233_A1.0180.94
96_V116_L1.0170.94
358_I462_H1.0150.94
66_P69_M1.0130.93
86_L129_V1.0110.93
461_E465_W1.0100.93
260_D269_D1.0100.93
256_I284_G1.0090.93
261_G370_T1.0070.93
257_V396_F1.0060.93
267_L333_N1.0040.93
22_L30_M1.0040.93
50_E63_Y1.0040.93
463_F572_I1.0020.93
277_D280_S1.0020.93
310_S317_V1.0020.93
76_I106_A1.0000.93
379_V442_S0.9950.93
684_R687_D0.9950.93
171_K174_A0.9940.93
508_A511_S0.9930.93
376_K382_D0.9890.93
460_A568_V0.9880.93
38_E41_E0.9840.92
441_R445_E0.9830.92
335_K365_T0.9810.92
106_A112_V0.9790.92
251_L359_F0.9790.92
474_I537_K0.9780.92
45_A48_A0.9760.92
425_V615_D0.9760.92
337_D362_V0.9750.92
461_E552_F0.9690.92
358_I459_V0.9690.92
47_V50_E0.9640.92
283_L451_F0.9610.92
463_F470_F0.9610.92
50_E55_I0.9590.91
334_P367_E0.9580.91
129_V132_I0.9540.91
443_V446_K0.9540.91
137_I187_Y0.9490.91
667_F672_F0.9480.91
280_S348_N0.9480.91
487_L497_V0.9450.91
286_H344_E0.9440.91
98_I127_G0.9430.91
236_T324_R0.9420.91
71_L130_I0.9420.91
489_F528_V0.9410.91
180_V198_V0.9390.91
600_T603_M0.9390.91
262_A370_T0.9360.90
638_V674_M0.9350.90
696_V700_E0.9350.90
102_E117_N0.9310.90
378_L443_V0.9290.90
230_M234_S0.9290.90
28_E42_L0.9260.90
258_T267_L0.9260.90
269_D320_M0.9250.90
299_P302_K0.9250.90
212_I614_T0.9250.90
77_S108_N0.9220.90
76_I86_L0.9200.90
244_D292_H0.9190.90
283_L347_I0.9190.90
517_R522_E0.9180.90
439_R445_E0.9140.89
369_M377_I0.9110.89
266_D560_I0.9090.89
676_G679_T0.9080.89
413_R457_E0.9050.89
68_K71_L0.9050.89
460_A554_T0.9040.89
254_Q272_T0.8990.89
369_M389_Y0.8960.88
314_V433_V0.8950.88
269_D371_Y0.8910.88
35_E38_E0.8910.88
272_T361_S0.8910.88
509_L532_S0.8910.88
644_F654_L0.8900.88
464_H472_Y0.8890.88
643_M689_I0.8890.88
254_Q284_G0.8820.88
538_Y555_H0.8810.88
462_H575_Y0.8790.87
221_L606_R0.8780.87
269_D312_Y0.8770.87
230_M233_A0.8770.87
22_L27_L0.8760.87
108_N159_K0.8750.87
240_I245_L0.8720.87
83_F97_F0.8710.87
267_L323_H0.8700.87
291_S573_R0.8690.87
116_L125_Q0.8680.87
661_T665_Y0.8680.87
424_K439_R0.8680.87
76_I129_V0.8660.87
23_T26_E0.8640.87
284_G359_F0.8610.86
241_D292_H0.8600.86
142_G182_V0.8600.86
153_V166_I0.8600.86
113_M130_I0.8590.86
413_R550_T0.8580.86
150_F165_F0.8580.86
175_A178_H0.8570.86
513_L516_V0.8570.86
256_I342_S0.8560.86
385_L388_K0.8560.86
186_S195_E0.8530.86
215_V614_T0.8510.86
320_M371_Y0.8490.86
622_Y626_K0.8460.85
466_M575_Y0.8460.85
631_F693_V0.8460.85
84_A103_L0.8450.85
351_G402_L0.8440.85
78_A161_T0.8420.85
251_L363_I0.8400.85
260_D312_Y0.8390.85
378_L396_F0.8380.85
401_R405_I0.8360.85
312_Y561_R0.8350.85
70_N115_R0.8340.85
25_Q29_E0.8330.84
175_A323_H0.8310.84
175_A204_H0.8240.84
279_G346_T0.8210.84
266_D312_Y0.8210.84
623_M693_V0.8200.84
415_A420_F0.8180.83
156_D214_S0.8150.83
206_N211_D0.8150.83
376_K380_D0.8140.83
135_R187_Y0.8140.83
507_R511_S0.8090.83
49_L52_K0.8090.83
165_F193_N0.8080.83
272_T344_E0.8070.83
655_V707_I0.8070.83
228_D299_P0.8070.83
345_M353_V0.8070.83
455_A556_F0.8060.82
377_I397_K0.8050.82
268_D312_Y0.8040.82
24_V40_K0.8020.82
226_P306_E0.8020.82
53_G56_V0.8000.82
275_K394_P0.7960.82
522_E526_S0.7960.82
367_E373_D0.7960.82
432_A625_D0.7950.82
46_L55_I0.7950.82
436_V651_I0.7950.82
231_E235_S0.7930.81
241_D247_D0.7900.81
356_H461_E0.7900.81
520_P688_E0.7880.81
452_M475_H0.7880.81
523_T646_E0.7880.81
643_M659_F0.7880.81
381_D386_K0.7860.81
620_A701_R0.7850.81
351_G405_I0.7850.81
369_M373_D0.7850.81
292_H360_Q0.7840.81
556_F569_H0.7840.81
48_A51_E0.7840.81
268_D561_R0.7830.81
144_Y198_V0.7820.81
693_V705_F0.7820.81
232_Q235_S0.7810.80
268_D371_Y0.7800.80
166_I196_G0.7800.80
459_V554_T0.7790.80
331_S560_I0.7790.80
426_L434_K0.7760.80
367_E392_L0.7750.80
42_L45_A0.7750.80
668_D673_A0.7750.80
441_R446_K0.7750.80
498_K505_H0.7740.80
253_D366_T0.7730.80
152_F193_N0.7710.80
88_P93_L0.7680.79
78_A84_A0.7680.79
635_I689_I0.7660.79
463_F571_L0.7660.79
65_I69_M0.7660.79
308_G599_H0.7660.79
245_L340_T0.7650.79
395_M398_D0.7650.79
269_D561_R0.7640.79
697_N700_E0.7600.79
402_L451_F0.7580.78
589_W592_R0.7570.78
269_D452_M0.7570.78
34_T38_E0.7560.78
372_S376_K0.7540.78
256_I273_V0.7530.78
374_V378_L0.7520.78
243_K246_K0.7520.78
211_D617_L0.7520.78
495_Y512_I0.7500.78
375_N443_V0.7480.77
166_I174_A0.7470.77
381_D397_K0.7470.77
229_A232_Q0.7460.77
495_Y519_R0.7440.77
97_F100_P0.7420.77
406_L409_K0.7420.77
303_E307_R0.7410.77
372_S442_S0.7410.77
292_H573_R0.7410.77
367_E391_P0.7380.77
98_I106_A0.7370.76
260_D452_M0.7360.76
255_V272_T0.7350.76
240_I247_D0.7330.76
107_M136_A0.7320.76
45_A49_L0.7300.76
57_R63_Y0.7290.76
240_I339_L0.7280.76
257_V273_V0.7270.75
405_I408_D0.7270.75
65_I71_L0.7270.75
643_M683_F0.7250.75
107_M137_I0.7220.75
397_K400_E0.7220.75
409_K412_D0.7220.75
252_R364_K0.7210.75
639_T654_L0.7200.75
275_K281_Y0.7190.75
261_G368_R0.7170.74
266_D558_S0.7160.74
240_I244_D0.7160.74
651_I703_I0.7160.74
616_D637_S0.7160.74
415_A453_L0.7130.74
449_E558_S0.7130.74
266_D269_D0.7120.74
375_N380_D0.7110.74
241_D245_L0.7100.74
488_E670_Q0.7100.74
568_V571_L0.7090.74
163_D193_N0.7080.74
690_T708_V0.7080.74
254_Q344_E0.7070.73
452_M558_S0.7070.73
330_C452_M0.7060.73
633_G689_I0.7050.73
403_A407_R0.7050.73
659_F694_V0.7050.73
268_D452_M0.7030.73
269_D449_E0.7020.73
647_L691_V0.7020.73
297_N305_L0.7020.73
662_D681_N0.7020.73
233_A236_T0.7000.73
334_P368_R0.6990.73
245_L337_D0.6980.72
282_K342_S0.6970.72
184_L187_Y0.6970.72
287_I452_M0.6960.72
244_D339_L0.6950.72
178_H323_H0.6950.72
229_A306_E0.6940.72
266_D449_E0.6940.72
117_N128_T0.6930.72
143_T179_K0.6930.72
72_I88_P0.6920.72
402_L405_I0.6910.72
24_V28_E0.6910.72
22_L26_E0.6900.72
167_P174_A0.6900.72
531_R612_R0.6880.71
280_S355_E0.6870.71
45_A52_K0.6860.71
163_D194_A0.6860.71
464_H542_S0.6850.71
283_L402_L0.6840.71
222_P306_E0.6840.71
255_V367_E0.6840.71
65_I68_K0.6830.71
106_A132_I0.6820.71
423_A438_I0.6820.71
449_E452_M0.6820.71
297_N302_K0.6820.71
260_D561_R0.6810.71
258_T365_T0.6800.71
40_K44_K0.6800.71
328_G336_V0.6790.70
174_A180_V0.6780.70
331_S558_S0.6770.70
645_V653_G0.6770.70
358_I572_I0.6770.70
294_V325_L0.6760.70
386_K393_V0.6750.70
472_Y542_S0.6750.70
107_M160_I0.6740.70
312_Y371_Y0.6730.70
533_M546_F0.6720.70
595_D599_H0.6720.70
403_A443_V0.6710.70
331_S371_Y0.6700.69
72_I86_L0.6700.69
260_D268_D0.6700.69
313_L614_T0.6700.69
410_R415_A0.6690.69
260_D371_Y0.6680.69
76_I104_N0.6680.69
371_Y452_M0.6680.69
542_S552_F0.6670.69
42_L46_L0.6670.69
58_T64_G0.6660.69
147_T150_F0.6660.69
423_A619_K0.6650.69
663_D678_R0.6650.69
257_V392_L0.6640.69
345_M454_V0.6640.69
49_L55_I0.6630.69
151_G176_E0.6630.69
260_D266_D0.6610.68
266_D536_A0.6600.68
79_H83_F0.6590.68
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185_T195_E0.6550.68
473_R536_A0.6540.68
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452_M561_R0.6430.66
181_V217_H0.6410.66
371_Y561_R0.6400.66
462_H576_L0.6400.66
265_K327_N0.6390.66
452_M560_I0.6380.66
329_I338_R0.6370.66
595_D598_E0.6370.66
24_V35_E0.6370.66
343_C459_V0.6360.65
143_T205_K0.6360.65
407_R417_D0.6360.65
634_M688_E0.6340.65
64_G70_N0.6330.65
98_I102_E0.6300.65
259_I269_D0.6300.65
287_I560_I0.6300.65
312_Y452_M0.6300.65
228_D231_E0.6290.65
102_E128_T0.6290.65
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540_P593_L0.6280.64
184_L188_P0.6280.64
46_L50_E0.6280.64
264_A368_R0.6280.64
610_A614_T0.6270.64
473_R538_Y0.6260.64
312_Y560_I0.6250.64
266_D330_C0.6240.64
271_V447_L0.6230.64
470_F554_T0.6230.64
371_Y560_I0.6230.64
445_E550_T0.6230.64
102_E126_E0.6230.64
664_Y676_G0.6230.64
673_A684_R0.6230.64
313_L318_I0.6220.64
260_D330_C0.6200.63
24_V50_E0.6200.63
623_M651_I0.6190.63
567_I596_I0.6180.63
465_W505_H0.6180.63
524_V634_M0.6180.63
25_Q39_F0.6180.63
245_L339_L0.6180.63
258_T334_P0.6170.63
260_D320_M0.6170.63
529_M533_M0.6170.63
281_Y401_R0.6170.63
290_V536_A0.6160.63
83_F95_D0.6160.63
177_G204_H0.6160.63
350_Q405_I0.6150.63
286_H340_T0.6150.63
471_I593_L0.6140.63
46_L49_L0.6120.62
374_V400_E0.6110.62
305_L592_R0.6110.62
419_D446_K0.6110.62
571_L593_L0.6110.62
329_I336_V0.6100.62
56_V64_G0.6100.62
290_V473_R0.6100.62
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216_I525_I0.6090.62
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656_H704_D0.6090.62
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415_A450_E0.6070.62
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86_L89_E0.6050.62
604_E611_E0.6040.61
39_F43_V0.6040.61
204_H323_H0.6040.61
266_D452_M0.6040.61
210_I214_S0.6030.61
266_D331_S0.6030.61
185_T188_P0.6030.61
36_A43_V0.6020.61
71_L115_R0.6020.61
144_Y166_I0.6020.61
367_E396_F0.5990.61
400_E447_L0.5980.61
335_K367_E0.5980.61
97_F126_E0.5980.61
36_A40_K0.5980.61
310_S319_P0.5980.61
669_E674_M0.5960.60
237_P324_R0.5960.60
325_L560_I0.5960.60
377_I386_K0.5960.60
249_R254_Q0.5960.60
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535_Q612_R0.5930.60
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283_L399_M0.5800.58
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336_V365_T0.5790.58
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255_V392_L0.5790.58
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258_T368_R0.5790.58
69_M72_I0.5790.58
74_G79_H0.5790.58
64_G68_K0.5780.58
225_F319_P0.5780.58
151_G171_K0.5770.58
344_E357_E0.5770.58
626_K693_V0.5770.58
27_L46_L0.5770.58
108_N157_D0.5760.58
266_D475_H0.5760.58
372_S444_A0.5750.58
56_V66_P0.5740.58
82_G97_F0.5740.58
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163_D166_I0.5740.58
398_D405_I0.5740.58
273_V286_H0.5730.57
392_L395_M0.5730.57
643_M707_I0.5720.57
143_T156_D0.5720.57
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240_I362_V0.5710.57
390_E393_V0.5710.57
74_G112_V0.5700.57
530_L604_E0.5690.57
229_A300_I0.5690.57
294_V547_G0.5680.57
420_F608_V0.5680.57
332_L548_L0.5680.57
44_K47_V0.5670.57
434_K437_V0.5660.56
144_Y176_E0.5660.56
178_H206_N0.5660.56
188_P194_A0.5660.56
290_V560_I0.5660.56
463_F575_Y0.5650.56
241_D339_L0.5650.56
139_R181_V0.5630.56
214_S314_V0.5620.56
495_Y516_V0.5610.56
255_V391_P0.5610.56
237_P244_D0.5610.56
555_H562_R0.5610.56
38_E42_L0.5600.56
601_S605_R0.5600.56
42_L49_L0.5600.56
380_D386_K0.5590.56
411_M514_D0.5590.56
262_A444_A0.5580.55
538_Y556_F0.5580.55
458_T461_E0.5570.55
409_K413_R0.5570.55
654_L704_D0.5560.55
272_T395_M0.5560.55
661_T706_E0.5560.55
31_L42_L0.5550.55
50_E56_V0.5550.55
473_R478_P0.5540.55
549_S623_M0.5530.55
321_I325_L0.5520.55
150_F195_E0.5520.55
288_A560_I0.5520.55
512_I516_V0.5520.55
260_D332_L0.5520.55
47_V61_D0.5510.55
96_V125_Q0.5510.55
73_K133_L0.5510.55
266_D320_M0.5510.55
269_D448_I0.5510.55
259_I396_F0.5500.54
157_D160_I0.5490.54
41_E44_K0.5490.54
86_L91_T0.5490.54
137_I160_I0.5490.54
343_C356_H0.5480.54
449_E536_A0.5480.54
500_T504_I0.5480.54
290_V475_H0.5470.54
129_V136_A0.5460.54
676_G680_G0.5460.54
266_D561_R0.5450.54
21_P58_T0.5450.54
278_D355_E0.5450.54
305_L600_T0.5440.54
79_H95_D0.5440.54
403_A451_F0.5440.54
347_I406_L0.5420.53
98_I129_V0.5420.53
107_M187_Y0.5410.53
459_V572_I0.5400.53
377_I385_L0.5390.53
449_E453_L0.5390.53
319_P351_G0.5390.53
108_N137_I0.5380.53
312_Y536_A0.5380.53
300_I326_S0.5370.53
476_E601_S0.5370.53
140_V164_I0.5370.53
601_S604_E0.5370.53
296_E592_R0.5360.53
452_M557_T0.5360.53
674_M707_I0.5350.52
31_L45_A0.5350.52
470_F568_V0.5340.52
20_K25_Q0.5340.52
238_D329_I0.5340.52
287_I558_S0.5340.52
261_G267_L0.5330.52
376_K381_D0.5330.52
423_A436_V0.5330.52
98_I112_V0.5330.52
20_K29_E0.5330.52
319_P327_N0.5330.52
66_P71_L0.5320.52
41_E52_K0.5320.52
320_M560_I0.5320.52
268_D475_H0.5310.52
425_V436_V0.5310.52
449_E560_I0.5300.52
373_D376_K0.5290.52
59_R69_M0.5290.52
386_K390_E0.5280.51
145_T176_E0.5280.51
675_I682_V0.5280.51
29_E32_N0.5270.51
290_V330_C0.5270.51
220_G603_M0.5260.51
286_H459_V0.5250.51
390_E394_P0.5250.51
269_D558_S0.5250.51
155_P159_K0.5250.51
146_E151_G0.5250.51
242_E246_K0.5240.51
509_L533_M0.5240.51
495_Y525_I0.5230.51
286_H617_L0.5230.51
260_D326_S0.5220.51
568_V572_I0.5220.51
141_V181_V0.5220.51
621_E624_L0.5220.51
408_D411_M0.5200.50
268_D320_M0.5190.50
422_E547_G0.5190.50
120_S123_S0.5190.50
31_L48_A0.5190.50
79_H84_A0.5190.50
29_E34_T0.5180.50
331_S452_M0.5180.50
57_R62_R0.5180.50
266_D332_L0.5180.50
616_D652_E0.5170.50
288_A312_Y0.5170.50
480_A502_G0.5160.50
268_D560_I0.5160.50
23_T29_E0.5150.50
341_L358_I0.5150.50
261_G264_A0.5150.50
85_F97_F0.5140.50
261_G445_E0.5140.50
40_K47_V0.5140.50
56_V62_R0.5140.50
261_G448_I0.5140.50
86_L103_L0.5130.49
167_P172_N0.5130.49
260_D560_I0.5130.49
493_F516_V0.5120.49
287_I320_M0.5120.49
28_E33_I0.5110.49
56_V131_R0.5100.49
35_E39_F0.5100.49
340_T365_T0.5080.49
251_L254_Q0.5070.49
265_K315_D0.5070.49
633_G693_V0.5070.49
261_G320_M0.5060.48
486_F547_G0.5060.48
139_R220_G0.5060.48
264_A319_P0.5060.48
357_E361_S0.5060.48
164_I184_L0.5060.48
44_K55_I0.5060.48
394_P397_K0.5050.48
502_G688_E0.5050.48
338_R410_R0.5050.48
24_V46_L0.5040.48
213_L217_H0.5030.48
657_V660_M0.5030.48
342_S360_Q0.5030.48
170_G185_T0.5030.48
422_E604_E0.5030.48
591_E595_D0.5030.48
239_T242_E0.5030.48
511_S529_M0.5020.48
599_H602_S0.5020.48
536_A561_R0.5010.48
435_D649_N0.5010.48
380_D397_K0.5010.48
69_M664_Y0.5010.48
221_L534_K0.5010.48
278_D349_S0.5010.48
538_Y562_R0.5000.48
316_R431_G0.5000.48
29_E39_F0.5000.48
72_I116_L0.5000.48
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2vnuD 1 0.8139 100 0.207 Contact Map
4ifdJ 1 0.8819 100 0.213 Contact Map
2id0A 1 0.8049 100 0.227 Contact Map
4ro1A 1 0.6816 100 0.231 Contact Map
4pmwA 1 0.819 100 0.232 Contact Map
2r7dA 1 0.5854 100 0.469 Contact Map
3bzcA 1 0.7407 100 0.875 Contact Map
1e3pA 3 0.5494 99.8 0.908 Contact Map
1go3E 1 0.2246 99.8 0.91 Contact Map
4qjfA 1 0.2272 99.7 0.918 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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