YVAC - BACSU - GREMLIN Contacts

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YVAC - Uncharacterized membrane protein YvaC

UniProt:	O32225	Sequences: MNKTAANNQRIMPIVKDAFRIHANPFPWKKAIGSGFASGFPVLVGALAGHTDYGLIASIGGFVYLYAGGESYKKRALKLLLVSIGIALSFGLGTLLSGMLWMMAAVLGLIGAAAMFIFSALGIQGPAPMFFVLAFLVSSGLPADPSQALFRAGLTFLGGIFAMGIALIGWLWNKHGPEGAVLQKTYHQLAACLSAVGTPGFHNAQHQTVLMLRTARQTVLGKGNRRKKSRHDERFFRLLEKADDIFIAIIHFSAETPDRETAQIEKALRQTGDMLANARVFNTFQINENESEPRRKLFEEINEVLYIASGRFDKQLDGEPSRLPSSFYFLRNAFDWKSPVLIRALKYGIVLFAADMFALAFGFARSYWIPLSAAAVMLGTTVVFTLHRAIQRSAGTVIGVILAGAILFFKPGGVYIAFCIAALQCLLEMLIVRNYALAVPFLTANALVITESMHGGAGAGYFMIARLTDVAVGSVIGLLGTMLLWRRFSTKRLPELVRNVIRLEGQFMEKLLTGQIADEHKLRVSLVRLRDAYDKALGEFPHANADALWPAISGAQHLGYYLLSAQAHRRPSAPFSDEEINQLRAFFEQAEQSFIMKRMPADIQVPHVPHYPRISKELSALYSGLRTAFEK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	631 (553)
Sequences:	2596 (2026)
Seq/√Len:	86.2

ECOLI - YHFK YCCS MDTO
BACSU - YVAC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
194_S	269_R	5.109	1.00
583_L	587_F	4.176	1.00
300_E	304_V	3.880	1.00
298_F	304_V	3.713	1.00
354_A	373_A	3.666	1.00
108_G	348_G	3.562	1.00
350_V	373_A	3.055	1.00
164_G	168_I	2.890	1.00
149_L	152_A	2.865	1.00
108_G	352_F	2.856	1.00
264_I	268_L	2.812	1.00
105_A	109_L	2.811	1.00
37_A	165_I	2.789	1.00
519_E	523_R	2.756	1.00
418_F	422_A	2.744	1.00
213_R	216_R	2.743	1.00
300_E	305_L	2.684	1.00
112_A	348_G	2.672	1.00
305_L	308_A	2.656	1.00
297_L	305_L	2.615	1.00
186_Y	189_L	2.604	1.00
239_L	245_I	2.544	1.00
368_W	396_T	2.524	1.00
248_A	251_H	2.467	1.00
328_Y	331_R	2.464	1.00
153_G	157_L	2.444	1.00
41_P	161_F	2.441	1.00
304_V	308_A	2.411	1.00
489_S	535_K	2.411	1.00
35_G	421_A	2.389	1.00
112_A	341_L	2.353	1.00
350_V	480_G	2.279	1.00
423_L	444_A	2.278	1.00
301_I	305_L	2.275	1.00
368_W	466_R	2.239	1.00
369_I	469_D	2.236	1.00
350_V	476_I	2.198	1.00
247_I	251_H	2.194	1.00
357_F	476_I	2.104	1.00
291_S	300_E	2.086	1.00
473_G	477_G	2.085	1.00
267_A	271_T	2.084	1.00
397_V	401_I	1.989	1.00
576_S	579_E	1.988	1.00
369_I	472_V	1.978	1.00
354_A	476_I	1.952	1.00
248_A	252_F	1.944	1.00
292_E	305_L	1.933	1.00
388_R	435_Y	1.925	1.00
31_A	425_C	1.923	1.00
207_Q	211_M	1.922	1.00
575_F	579_E	1.908	1.00
575_F	578_E	1.899	1.00
365_R	368_W	1.898	1.00
372_S	470_V	1.894	1.00
302_N	305_L	1.893	1.00
301_I	307_I	1.885	1.00
573_A	576_S	1.882	1.00
111_G	351_L	1.881	1.00
258_D	266_K	1.879	1.00
300_E	307_I	1.877	1.00
244_D	247_I	1.872	1.00
244_D	253_S	1.846	1.00
121_L	124_Q	1.843	1.00
291_S	298_F	1.823	1.00
294_R	301_I	1.822	1.00
556_Q	559_G	1.809	1.00
41_P	54_G	1.801	1.00
300_E	308_A	1.797	1.00
239_L	243_D	1.788	1.00
259_R	262_A	1.766	1.00
293_P	297_L	1.756	1.00
243_D	247_I	1.753	1.00
107_L	135_F	1.749	1.00
590_A	594_F	1.746	1.00
368_W	443_T	1.744	1.00
87_A	156_F	1.741	1.00
261_T	265_E	1.738	1.00
235_F	238_L	1.716	1.00
258_D	261_T	1.715	1.00
472_V	475_V	1.715	1.00
205_Q	209_V	1.705	1.00
217_Q	221_G	1.703	1.00
293_P	296_K	1.667	1.00
277_N	280_V	1.659	1.00
298_F	301_I	1.644	1.00
526_L	530_R	1.634	1.00
279_R	282_N	1.618	1.00
343_R	380_T	1.612	1.00
212_L	215_A	1.606	1.00
191_A	295_R	1.603	1.00
396_T	470_V	1.603	1.00
244_D	248_A	1.600	1.00
298_F	305_L	1.587	1.00
275_L	282_N	1.572	1.00
243_D	246_F	1.569	1.00
400_V	463_M	1.547	1.00
233_E	239_L	1.545	1.00
505_G	584_R	1.543	1.00
259_R	263_Q	1.527	1.00
272_G	281_F	1.522	1.00
275_L	279_R	1.521	1.00
187_H	276_A	1.520	1.00
195_A	204_A	1.511	1.00
79_L	163_M	1.501	1.00
238_L	241_K	1.499	1.00
244_D	252_F	1.496	0.99
83_S	159_G	1.493	0.99
368_W	473_G	1.485	0.99
294_R	303_E	1.471	0.99
471_A	475_V	1.471	0.99
252_F	256_T	1.469	0.99
158_G	162_A	1.465	0.99
229_S	234_R	1.460	0.99
209_V	213_R	1.439	0.99
412_G	415_Y	1.434	0.99
268_L	272_G	1.434	0.99
265_E	272_G	1.431	0.99
70_E	74_K	1.431	0.99
251_H	256_T	1.430	0.99
101_W	105_A	1.430	0.99
324_P	327_F	1.425	0.99
327_F	331_R	1.420	0.99
115_M	119_S	1.418	0.99
557_H	561_Y	1.416	0.99
583_L	586_F	1.411	0.99
246_F	250_I	1.410	0.99
228_K	231_H	1.409	0.99
253_S	256_T	1.406	0.99
556_Q	561_Y	1.402	0.99
190_A	272_G	1.402	0.99
265_E	268_L	1.401	0.99
376_V	435_Y	1.400	0.99
331_R	334_F	1.396	0.99
563_L	566_Q	1.391	0.99
236_F	240_E	1.390	0.99
396_T	443_T	1.389	0.99
41_P	45_G	1.374	0.99
296_K	299_E	1.373	0.99
115_M	347_Y	1.370	0.99
147_Q	151_R	1.368	0.99
298_F	302_N	1.366	0.99
395_G	466_R	1.363	0.99
322_R	325_S	1.361	0.99
569_R	572_S	1.355	0.99
265_E	269_R	1.353	0.99
247_I	255_E	1.346	0.99
246_F	251_H	1.345	0.99
588_E	591_E	1.342	0.99
357_F	472_V	1.341	0.99
530_R	556_Q	1.335	0.99
248_A	256_T	1.335	0.99
446_A	450_T	1.328	0.99
268_L	275_L	1.325	0.99
380_T	489_S	1.322	0.99
208_T	218_T	1.317	0.99
107_L	110_I	1.315	0.99
36_F	479_L	1.313	0.99
392_R	435_Y	1.312	0.99
342_I	485_W	1.311	0.99
245_I	251_H	1.311	0.99
236_F	242_A	1.307	0.99
398_I	440_P	1.305	0.99
270_Q	280_V	1.305	0.99
291_S	305_L	1.304	0.99
504_E	555_A	1.302	0.99
96_L	106_V	1.300	0.99
369_I	372_S	1.296	0.99
291_S	294_R	1.295	0.99
252_F	255_E	1.294	0.99
438_A	442_L	1.292	0.99
209_V	221_G	1.292	0.99
245_I	253_S	1.287	0.98
290_E	302_N	1.285	0.98
297_L	302_N	1.281	0.98
293_P	300_E	1.279	0.98
409_F	415_Y	1.276	0.98
40_F	161_F	1.275	0.98
290_E	300_E	1.275	0.98
136_L	139_S	1.267	0.98
164_G	167_L	1.263	0.98
271_T	275_L	1.259	0.98
209_V	212_L	1.253	0.98
269_R	272_G	1.251	0.98
246_F	253_S	1.249	0.98
248_A	254_A	1.248	0.98
584_R	588_E	1.239	0.98
417_A	421_A	1.232	0.98
267_A	270_Q	1.230	0.98
242_A	251_H	1.225	0.98
208_T	215_A	1.223	0.98
246_F	252_F	1.222	0.98
95_L	99_M	1.217	0.98
550_P	554_G	1.216	0.98
297_L	301_I	1.210	0.98
183_Q	187_H	1.202	0.98
290_E	298_F	1.197	0.98
294_R	298_F	1.195	0.97
524_V	528_R	1.193	0.97
355_D	370_P	1.190	0.97
402_L	440_P	1.186	0.97
297_L	300_E	1.182	0.97
291_S	295_R	1.181	0.97
296_K	307_I	1.180	0.97
226_R	232_D	1.174	0.97
222_K	225_R	1.170	0.97
129_M	133_L	1.170	0.97
260_E	265_E	1.169	0.97
502_R	591_E	1.169	0.97
299_E	302_N	1.164	0.97
264_I	275_L	1.163	0.97
556_Q	562_L	1.161	0.97
297_L	307_I	1.159	0.97
350_V	389_A	1.158	0.97
351_L	374_A	1.156	0.97
366_S	370_P	1.156	0.97
201_F	212_L	1.154	0.97
274_M	281_F	1.153	0.97
415_Y	418_F	1.151	0.97
346_K	368_W	1.148	0.97
555_A	559_G	1.147	0.97
435_Y	439_V	1.145	0.97
520_H	523_R	1.143	0.97
439_V	442_L	1.138	0.97
156_F	160_I	1.137	0.97
30_K	33_G	1.137	0.97
327_F	330_L	1.136	0.97
148_A	152_A	1.136	0.97
576_S	580_I	1.134	0.97
369_I	476_I	1.133	0.97
549_W	552_I	1.132	0.97
246_F	255_E	1.131	0.97
82_V	127_A	1.130	0.96
377_M	396_T	1.129	0.96
123_I	126_P	1.122	0.96
260_E	264_I	1.122	0.96
245_I	248_A	1.121	0.96
295_R	305_L	1.117	0.96
275_L	281_F	1.115	0.96
204_A	207_Q	1.114	0.96
263_Q	267_A	1.114	0.96
243_D	248_A	1.112	0.96
292_E	298_F	1.110	0.96
104_A	352_F	1.108	0.96
333_A	336_W	1.107	0.96
302_N	307_I	1.105	0.96
292_E	297_L	1.103	0.96
259_R	264_I	1.102	0.96
191_A	204_A	1.100	0.96
242_A	248_A	1.100	0.96
59_I	134_A	1.097	0.96
296_K	300_E	1.096	0.96
104_A	107_L	1.089	0.96
545_A	562_L	1.086	0.96
270_Q	273_D	1.086	0.96
210_L	215_A	1.086	0.96
420_I	448_V	1.085	0.96
300_E	303_E	1.084	0.96
248_A	253_S	1.082	0.95
301_I	304_V	1.081	0.95
356_M	360_A	1.079	0.95
585_A	589_Q	1.079	0.95
397_V	467_L	1.075	0.95
251_H	254_A	1.074	0.95
267_A	272_G	1.074	0.95
243_D	251_H	1.073	0.95
290_E	299_E	1.070	0.95
466_R	473_G	1.068	0.95
273_D	276_A	1.068	0.95
266_K	270_Q	1.067	0.95
59_I	62_F	1.062	0.95
297_L	304_V	1.061	0.95
106_V	110_I	1.058	0.95
212_L	219_V	1.058	0.95
60_G	346_K	1.058	0.95
205_Q	208_T	1.054	0.95
183_Q	272_G	1.054	0.95
574_P	577_D	1.053	0.95
261_T	269_R	1.049	0.95
157_L	299_E	1.046	0.95
297_L	303_E	1.045	0.95
294_R	306_Y	1.043	0.95
31_A	34_S	1.041	0.94
179_G	190_A	1.040	0.94
582_Q	594_F	1.040	0.94
582_Q	586_F	1.039	0.94
450_T	462_F	1.033	0.94
400_V	467_L	1.029	0.94
582_Q	593_S	1.028	0.94
586_F	589_Q	1.028	0.94
560_Y	564_S	1.023	0.94
423_L	441_F	1.023	0.94
101_W	344_A	1.019	0.94
292_E	296_K	1.019	0.94
587_F	597_K	1.016	0.94
257_P	260_E	1.014	0.94
546_D	550_P	1.012	0.94
102_M	405_A	1.009	0.93
251_H	255_E	1.007	0.93
333_A	338_S	1.006	0.93
372_S	392_R	1.005	0.93
258_D	264_I	1.000	0.93
260_E	267_A	1.000	0.93
262_A	275_L	0.999	0.93
217_Q	220_L	0.992	0.93
228_K	237_R	0.989	0.93
239_L	248_A	0.988	0.93
229_S	237_R	0.988	0.93
465_A	469_D	0.987	0.93
83_S	96_L	0.987	0.93
245_I	250_I	0.984	0.93
303_E	307_I	0.984	0.93
246_F	249_I	0.984	0.93
72_Y	170_W	0.983	0.93
550_P	555_A	0.982	0.93
182_L	261_T	0.981	0.92
107_L	115_M	0.979	0.92
294_R	300_E	0.978	0.92
290_E	305_L	0.978	0.92
292_E	300_E	0.977	0.92
381_T	384_F	0.973	0.92
434_N	440_P	0.972	0.92
218_T	221_G	0.970	0.92
562_L	565_A	0.970	0.92
556_Q	563_L	0.968	0.92
238_L	242_A	0.968	0.92
278_A	281_F	0.968	0.92
79_L	518_D	0.966	0.92
300_E	306_Y	0.962	0.92
39_G	421_A	0.961	0.92
428_E	441_F	0.958	0.92
226_R	238_L	0.953	0.91
560_Y	563_L	0.952	0.91
193_L	247_I	0.951	0.91
148_A	151_R	0.951	0.91
200_G	203_N	0.950	0.91
382_V	540_F	0.950	0.91
208_T	212_L	0.946	0.91
271_T	282_N	0.946	0.91
578_E	592_Q	0.945	0.91
49_G	53_Y	0.945	0.91
293_P	299_E	0.944	0.91
293_P	303_E	0.943	0.91
212_L	220_L	0.942	0.91
85_G	89_S	0.942	0.91
292_E	304_V	0.941	0.91
586_F	593_S	0.940	0.91
523_R	535_K	0.939	0.91
188_Q	191_A	0.934	0.91
293_P	305_L	0.934	0.91
338_S	341_L	0.933	0.90
344_A	348_G	0.932	0.90
247_I	256_T	0.929	0.90
440_P	443_T	0.928	0.90
460_G	464_I	0.928	0.90
396_T	466_R	0.928	0.90
48_A	51_T	0.924	0.90
190_A	471_A	0.920	0.90
377_M	477_G	0.920	0.90
376_V	473_G	0.916	0.90
443_T	466_R	0.916	0.90
236_F	241_K	0.914	0.90
247_I	253_S	0.910	0.89
33_G	171_L	0.910	0.89
190_A	265_E	0.910	0.89
214_T	218_T	0.908	0.89
250_I	254_A	0.903	0.89
235_F	245_I	0.901	0.89
261_T	268_L	0.900	0.89
349_I	480_G	0.899	0.89
58_S	62_F	0.897	0.89
191_A	292_E	0.893	0.88
263_Q	278_A	0.890	0.88
36_F	498_R	0.889	0.88
110_I	135_F	0.888	0.88
479_L	483_L	0.885	0.88
536_A	554_G	0.884	0.88
293_P	308_A	0.884	0.88
318_G	494_P	0.882	0.88
261_T	266_K	0.877	0.88
203_N	213_R	0.876	0.87
110_I	114_A	0.874	0.87
371_L	421_A	0.873	0.87
389_A	478_L	0.873	0.87
250_I	253_S	0.872	0.87
146_S	150_F	0.868	0.87
320_P	327_F	0.867	0.87
212_L	216_R	0.865	0.87
136_L	141_L	0.862	0.87
577_D	580_I	0.860	0.87
240_E	246_F	0.859	0.86
49_G	52_D	0.858	0.86
589_Q	592_Q	0.857	0.86
290_E	304_V	0.855	0.86
204_A	213_R	0.851	0.86
357_F	413_G	0.849	0.86
552_I	556_Q	0.849	0.86
232_D	236_F	0.849	0.86
207_Q	213_R	0.847	0.86
554_G	557_H	0.847	0.86
92_L	106_V	0.845	0.86
294_R	302_N	0.844	0.85
239_L	242_A	0.844	0.85
201_F	206_H	0.843	0.85
293_P	304_V	0.843	0.85
502_R	595_I	0.842	0.85
199_P	210_L	0.842	0.85
435_Y	473_G	0.841	0.85
555_A	558_L	0.838	0.85
293_P	298_F	0.837	0.85
295_R	298_F	0.834	0.85
563_L	567_A	0.833	0.85
574_P	579_E	0.832	0.85
354_A	369_I	0.831	0.85
508_M	512_L	0.828	0.84
592_Q	596_M	0.828	0.84
299_E	306_Y	0.826	0.84
296_K	302_N	0.826	0.84
272_G	280_V	0.824	0.84
298_F	306_Y	0.823	0.84
165_I	168_I	0.822	0.84
258_D	272_G	0.816	0.84
144_D	150_F	0.815	0.83
295_R	299_E	0.814	0.83
35_G	39_G	0.814	0.83
148_A	154_L	0.814	0.83
87_A	152_A	0.813	0.83
342_I	374_A	0.813	0.83
580_I	584_R	0.813	0.83
556_Q	566_Q	0.812	0.83
36_F	139_S	0.809	0.83
558_L	568_H	0.808	0.83
264_I	267_A	0.808	0.83
263_Q	281_F	0.806	0.83
40_F	320_P	0.806	0.83
346_K	474_S	0.806	0.83
277_N	282_N	0.804	0.83
229_S	236_F	0.803	0.83
579_E	583_L	0.803	0.83
145_P	559_G	0.802	0.82
509_E	584_R	0.802	0.82
298_F	303_E	0.801	0.82
233_E	237_R	0.801	0.82
584_R	592_Q	0.801	0.82
586_F	590_A	0.799	0.82
103_M	114_A	0.796	0.82
63_V	137_V	0.796	0.82
320_P	330_L	0.796	0.82
219_V	224_N	0.794	0.82
193_L	249_I	0.793	0.82
209_V	216_R	0.792	0.82
52_D	109_L	0.788	0.81
259_R	268_L	0.788	0.81
289_N	308_A	0.787	0.81
44_V	48_A	0.787	0.81
580_I	594_F	0.784	0.81
372_S	382_V	0.784	0.81
191_A	195_A	0.784	0.81
62_F	66_Y	0.783	0.81
208_T	211_M	0.777	0.80
358_A	469_D	0.776	0.80
258_D	262_A	0.775	0.80
270_Q	552_I	0.773	0.80
291_S	301_I	0.771	0.80
582_Q	589_Q	0.769	0.80
353_A	356_M	0.768	0.80
345_L	401_I	0.768	0.80
211_M	218_T	0.767	0.80
35_G	425_C	0.764	0.79
419_C	468_T	0.764	0.79
378_L	388_R	0.762	0.79
83_S	187_H	0.762	0.79
245_I	256_T	0.761	0.79
585_A	592_Q	0.761	0.79
588_E	592_Q	0.758	0.79
113_A	117_I	0.756	0.79
591_E	595_I	0.756	0.79
367_Y	470_V	0.756	0.79
250_I	256_T	0.754	0.78
109_L	113_A	0.752	0.78
530_R	534_D	0.752	0.78
381_T	428_E	0.752	0.78
202_H	205_Q	0.751	0.78
273_D	277_N	0.750	0.78
61_G	158_G	0.748	0.78
414_V	417_A	0.748	0.78
197_G	298_F	0.748	0.78
592_Q	595_I	0.747	0.78
573_A	579_E	0.747	0.78
28_W	63_V	0.746	0.78
446_A	504_E	0.746	0.78
185_T	189_L	0.746	0.78
348_G	352_F	0.745	0.78
330_L	478_L	0.744	0.77
382_V	488_F	0.744	0.77
67_A	79_L	0.744	0.77
503_L	506_Q	0.743	0.77
342_I	385_T	0.743	0.77
343_R	383_V	0.740	0.77
274_M	289_N	0.739	0.77
203_N	206_H	0.738	0.77
83_S	420_I	0.735	0.77
274_M	279_R	0.732	0.76
262_A	324_P	0.727	0.76
249_I	253_S	0.726	0.76
61_G	570_R	0.725	0.76
207_Q	280_V	0.725	0.76
132_V	136_L	0.725	0.76
302_N	475_V	0.722	0.75
212_L	239_L	0.722	0.75
260_E	266_K	0.721	0.75
115_M	122_G	0.720	0.75
589_Q	596_M	0.719	0.75
343_R	477_G	0.718	0.75
248_A	255_E	0.716	0.75
146_S	149_L	0.715	0.75
151_R	154_L	0.713	0.74
199_P	205_Q	0.712	0.74
338_S	343_R	0.711	0.74
89_S	93_G	0.710	0.74
299_E	303_E	0.709	0.74
576_S	584_R	0.709	0.74
262_A	291_S	0.708	0.74
260_E	278_A	0.706	0.74
430_L	437_L	0.703	0.73
325_S	330_L	0.702	0.73
274_M	278_A	0.701	0.73
403_A	473_G	0.701	0.73
220_L	225_R	0.698	0.73
578_E	586_F	0.698	0.73
230_R	248_A	0.697	0.73
151_R	159_G	0.697	0.73
533_Y	541_P	0.697	0.73
218_T	408_F	0.694	0.72
561_Y	566_Q	0.694	0.72
580_I	593_S	0.692	0.72
547_A	557_H	0.692	0.72
589_Q	597_K	0.691	0.72
271_T	280_V	0.691	0.72
291_S	303_E	0.690	0.72
189_L	397_V	0.690	0.72
102_M	106_V	0.687	0.72
263_Q	268_L	0.684	0.71
230_R	233_E	0.683	0.71
354_A	508_M	0.683	0.71
365_R	450_T	0.680	0.71
575_F	585_A	0.679	0.71
132_V	135_F	0.678	0.71
270_Q	274_M	0.677	0.71
368_W	469_D	0.677	0.71
289_N	299_E	0.676	0.70
226_R	231_H	0.675	0.70
275_L	278_A	0.675	0.70
241_K	245_I	0.675	0.70
231_H	235_F	0.674	0.70
303_E	353_A	0.674	0.70
559_G	567_A	0.674	0.70
510_K	513_T	0.673	0.70
492_R	496_L	0.672	0.70
235_F	241_K	0.672	0.70
227_K	236_F	0.671	0.70
257_P	264_I	0.670	0.70
303_E	306_Y	0.668	0.70
564_S	570_R	0.667	0.69
261_T	272_G	0.667	0.69
560_Y	566_Q	0.665	0.69
580_I	587_F	0.664	0.69
31_A	480_G	0.664	0.69
112_A	119_S	0.664	0.69
559_G	569_R	0.663	0.69
193_L	383_V	0.662	0.69
415_Y	419_C	0.662	0.69
203_N	207_Q	0.662	0.69
405_A	409_F	0.660	0.69
423_L	427_L	0.660	0.69
229_S	232_D	0.658	0.68
368_W	450_T	0.657	0.68
92_L	105_A	0.657	0.68
206_H	210_L	0.655	0.68
207_Q	401_I	0.654	0.68
298_F	308_A	0.654	0.68
587_F	592_Q	0.654	0.68
589_Q	593_S	0.654	0.68
41_P	44_V	0.653	0.68
41_P	178_E	0.652	0.68
586_F	597_K	0.651	0.68
344_A	442_L	0.650	0.67
309_S	319_E	0.649	0.67
176_G	179_G	0.648	0.67
428_E	565_A	0.644	0.67
388_R	431_I	0.644	0.67
585_A	588_E	0.643	0.67
257_P	273_D	0.643	0.67
582_Q	592_Q	0.643	0.67
182_L	215_A	0.641	0.66
189_L	246_F	0.640	0.66
234_R	237_R	0.639	0.66
547_A	550_P	0.639	0.66
389_A	481_T	0.638	0.66
380_T	507_F	0.638	0.66
590_A	596_M	0.637	0.66
209_V	215_A	0.635	0.66
394_A	551_A	0.634	0.66
301_I	306_Y	0.633	0.65
219_V	222_K	0.632	0.65
403_A	447_L	0.631	0.65
224_N	228_K	0.630	0.65
270_Q	275_L	0.630	0.65
406_I	410_K	0.630	0.65
213_R	220_L	0.627	0.65
94_T	152_A	0.627	0.65
500_V	555_A	0.627	0.65
265_E	275_L	0.627	0.65
576_S	585_A	0.627	0.65
199_P	203_N	0.626	0.65
215_A	223_G	0.626	0.65
189_L	306_Y	0.625	0.64
385_T	403_A	0.625	0.64
265_E	278_A	0.625	0.64
488_F	536_A	0.624	0.64
553_S	557_H	0.624	0.64
525_S	528_R	0.623	0.64
423_L	467_L	0.623	0.64
203_N	210_L	0.622	0.64
142_P	149_L	0.622	0.64
302_N	583_L	0.622	0.64
152_A	487_R	0.622	0.64
428_E	485_W	0.621	0.64
323_L	329_F	0.621	0.64
49_G	55_L	0.619	0.64
94_T	151_R	0.619	0.64
269_R	279_R	0.619	0.64
552_I	563_L	0.619	0.64
295_R	468_T	0.618	0.64
203_N	277_N	0.618	0.64
112_A	116_F	0.616	0.63
393_S	474_S	0.616	0.63
66_Y	427_L	0.614	0.63
271_T	278_A	0.613	0.63
215_A	218_T	0.613	0.63
102_M	360_A	0.613	0.63
31_A	429_M	0.612	0.63
500_V	522_L	0.612	0.63
382_V	470_V	0.612	0.63
156_F	159_G	0.610	0.63
545_A	556_Q	0.610	0.63
101_W	345_L	0.609	0.62
378_L	381_T	0.609	0.62
403_A	431_I	0.609	0.62
334_F	353_A	0.608	0.62
334_F	338_S	0.608	0.62
584_R	591_E	0.608	0.62
396_T	452_S	0.607	0.62
59_I	404_G	0.605	0.62
67_A	130_F	0.603	0.62
71_S	268_L	0.603	0.62
216_R	236_F	0.603	0.62
290_E	295_R	0.601	0.61
578_E	596_M	0.601	0.61
376_V	474_S	0.601	0.61
405_A	475_V	0.600	0.61
345_L	349_I	0.599	0.61
303_E	308_A	0.597	0.61
445_N	449_I	0.591	0.60
40_F	101_W	0.591	0.60
212_L	271_T	0.590	0.60
243_D	252_F	0.590	0.60
249_I	256_T	0.590	0.60
268_L	271_T	0.590	0.60
591_E	596_M	0.589	0.60
571_P	583_L	0.585	0.59
257_P	268_L	0.585	0.59
214_T	236_F	0.584	0.59
275_L	280_V	0.584	0.59
464_I	468_T	0.583	0.59
260_E	263_Q	0.582	0.59
391_Q	434_N	0.581	0.59
268_L	282_N	0.579	0.59
155_T	158_G	0.579	0.59
238_L	377_M	0.577	0.58
263_Q	273_D	0.576	0.58
234_R	238_L	0.575	0.58
576_S	583_L	0.574	0.58
579_E	591_E	0.573	0.58
545_A	549_W	0.573	0.58
29_K	33_G	0.573	0.58
273_D	297_L	0.573	0.58
576_S	587_F	0.573	0.58
372_S	439_V	0.572	0.58
263_Q	271_T	0.572	0.58
488_F	540_F	0.572	0.58
204_A	212_L	0.569	0.57
519_E	525_S	0.569	0.57
191_A	207_Q	0.569	0.57
190_A	349_I	0.568	0.57
290_E	297_L	0.568	0.57
431_I	438_A	0.568	0.57
498_R	505_G	0.568	0.57
216_R	220_L	0.567	0.57
440_P	446_A	0.567	0.57
153_G	596_M	0.567	0.57
28_W	404_G	0.566	0.57
89_S	155_T	0.565	0.57
234_R	240_E	0.565	0.57
372_S	539_E	0.565	0.57
259_R	280_V	0.565	0.57
119_S	340_V	0.564	0.57
265_E	274_M	0.564	0.57
156_F	269_R	0.562	0.56
258_D	273_D	0.562	0.56
257_P	265_E	0.561	0.56
57_A	60_G	0.560	0.56
360_A	405_A	0.560	0.56
391_Q	436_A	0.559	0.56
322_R	330_L	0.559	0.56
150_F	153_G	0.558	0.56
388_R	392_R	0.557	0.56
341_L	407_L	0.557	0.56
265_E	282_N	0.557	0.56
460_G	463_M	0.556	0.56
29_K	173_N	0.553	0.55
35_G	45_G	0.552	0.55
346_K	484_L	0.552	0.55
164_G	585_A	0.551	0.55
192_C	246_F	0.551	0.55
564_S	567_A	0.549	0.55
72_Y	75_R	0.549	0.55
579_E	586_F	0.549	0.55
204_A	210_L	0.548	0.54
537_L	541_P	0.548	0.54
579_E	589_Q	0.545	0.54
235_F	246_F	0.545	0.54
553_S	560_Y	0.544	0.54
201_F	422_A	0.543	0.54
470_V	488_F	0.541	0.54
368_W	477_G	0.541	0.54
244_D	255_E	0.540	0.53
31_A	35_G	0.540	0.53
390_I	394_A	0.539	0.53
183_Q	419_C	0.539	0.53
273_D	280_V	0.539	0.53
33_G	439_V	0.538	0.53
321_S	326_S	0.538	0.53
282_N	397_V	0.538	0.53
258_D	265_E	0.537	0.53
260_E	272_G	0.537	0.53
223_G	226_R	0.536	0.53
206_H	212_L	0.535	0.53
566_Q	569_R	0.535	0.53
261_T	274_M	0.534	0.53
346_K	523_R	0.533	0.52
477_G	481_T	0.533	0.52
28_W	31_A	0.532	0.52
415_Y	429_M	0.532	0.52
219_V	223_G	0.532	0.52
503_L	525_S	0.531	0.52
214_T	219_V	0.531	0.52
263_Q	274_M	0.530	0.52
490_T	548_L	0.529	0.52
108_G	459_A	0.529	0.52
244_D	254_A	0.529	0.52
584_R	590_A	0.529	0.52
556_Q	560_Y	0.529	0.52
584_R	593_S	0.528	0.52
135_F	139_S	0.527	0.52
244_D	249_I	0.527	0.52
166_A	172_W	0.527	0.52
263_Q	275_L	0.527	0.52
56_I	60_G	0.526	0.52
320_P	325_S	0.526	0.52
422_A	471_A	0.526	0.52
560_Y	567_A	0.525	0.51
554_G	559_G	0.524	0.51
340_V	378_L	0.524	0.51
112_A	344_A	0.524	0.51
319_E	325_S	0.524	0.51
121_L	128_P	0.523	0.51
88_L	109_L	0.523	0.51
387_H	391_Q	0.523	0.51
462_F	476_I	0.523	0.51
84_I	88_L	0.522	0.51
296_K	305_L	0.522	0.51
578_E	582_Q	0.522	0.51
84_I	156_F	0.522	0.51
370_P	450_T	0.522	0.51
376_V	400_V	0.522	0.51
271_T	274_M	0.520	0.51
371_L	439_V	0.520	0.51
63_V	66_Y	0.519	0.51
290_E	296_K	0.519	0.51
363_F	407_L	0.519	0.51
249_I	593_S	0.518	0.50
367_Y	469_D	0.518	0.50
443_T	450_T	0.518	0.50
292_E	306_Y	0.518	0.50
384_F	519_E	0.518	0.50
271_T	406_I	0.517	0.50
165_I	169_G	0.517	0.50
574_P	594_F	0.517	0.50
213_R	219_V	0.517	0.50
545_A	550_P	0.515	0.50
209_V	220_L	0.515	0.50
117_I	362_G	0.515	0.50
370_P	462_F	0.513	0.50
578_E	588_E	0.513	0.50
126_P	447_L	0.513	0.50
309_S	356_M	0.512	0.50
103_M	366_S	0.512	0.50
296_K	303_E	0.512	0.50
294_R	297_L	0.511	0.50
575_F	580_I	0.511	0.50
124_Q	140_G	0.511	0.50
502_R	505_G	0.510	0.49
163_M	405_A	0.509	0.49
200_G	204_A	0.509	0.49
164_G	268_L	0.509	0.49
328_Y	353_A	0.508	0.49
326_S	330_L	0.508	0.49
424_Q	427_L	0.507	0.49
70_E	73_K	0.507	0.49
181_V	215_A	0.505	0.49
585_A	590_A	0.505	0.49
327_F	333_A	0.504	0.49
560_Y	569_R	0.504	0.49
177_P	346_K	0.502	0.48
532_A	536_A	0.502	0.48
295_R	302_N	0.502	0.48
119_S	346_K	0.501	0.48
414_V	426_L	0.500	0.48
194_S	274_M	0.500	0.48

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3wdoA	1	0.3693	41.1	0.965	Contact Map
3effK	4	0.1997	16.6	0.972	Contact Map
4hw4A	2	0.0951	15.5	0.972	Contact Map
4n78F	1	0.1933	14	0.973	Contact Map
4mndA	2	0.2647	11.8	0.973	Contact Map
3s84A	2	0.206	10.3	0.974	Contact Map
2kmfA	1	0.1823	9.7	0.974	Contact Map
2ld6A	1	0.1965	8.9	0.975	Contact Map
4l6yA	2	0.2488	8.4	0.975	Contact Map
4aj51	2	0.1014	7.8	0.976	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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