GREMLIN Database
COPZ - Copper chaperone CopZ
UniProt: O32221 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 69 (64)
Sequences: 6632 (4982)
Seq/√Len: 622.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
9_E66_D2.8401.00
23_S63_Q2.2801.00
4_K46_F2.2561.00
52_S55_D2.2461.00
21_E25_G2.1511.00
5_T41_K2.1081.00
13_C16_C2.0801.00
32_A45_S1.9651.00
5_T43_D1.9551.00
61_E66_D1.7681.00
8_V42_V1.7331.00
18_K22_T1.7111.00
24_V42_V1.6621.00
17_V37_L1.6441.00
47_D50_K1.5791.00
8_V11_M1.5691.00
11_M20_V1.5651.00
57_A67_V1.4761.00
31_S45_S1.3881.00
31_S47_D1.3761.00
27_L59_A1.3601.00
23_S59_A1.3111.00
58_D62_D1.3011.00
19_A63_Q1.1911.00
12_S19_A1.1621.00
14_Q38_E1.1451.00
44_V56_I1.1011.00
23_S27_L1.0571.00
55_D58_D1.0281.00
4_K53_V1.0231.00
24_V33_V1.0071.00
54_K58_D0.9931.00
36_N39_A0.9921.00
58_D61_E0.9631.00
25_G33_V0.9561.00
24_V56_I0.9511.00
53_V57_A0.9301.00
14_Q17_V0.9271.00
7_Q67_V0.9251.00
60_I66_D0.9211.00
30_V56_I0.9021.00
59_A63_Q0.8831.00
10_G66_D0.8821.00
46_F52_S0.8591.00
20_V63_Q0.8441.00
14_Q18_K0.8401.00
9_E40_G0.8371.00
46_F50_K0.8251.00
7_Q40_G0.8241.00
35_V42_V0.8201.00
10_G60_I0.8081.00
6_L60_I0.7841.00
25_G32_A0.7791.00
28_D50_K0.7781.00
15_H18_K0.7731.00
42_V60_I0.7611.00
46_F56_I0.7551.00
30_V33_V0.7491.00
37_L40_G0.7321.00
6_L67_V0.7231.00
54_K57_A0.7151.00
51_V56_I0.6981.00
15_H38_E0.6961.00
15_H19_A0.6791.00
19_A23_S0.6771.00
17_V21_E0.6441.00
21_E34_H0.6261.00
51_V55_D0.6241.00
42_V67_V0.6231.00
30_V51_V0.6221.00
20_V60_I0.6221.00
6_L53_V0.6191.00
57_A61_E0.6141.00
24_V59_A0.6121.00
27_L51_V0.6051.00
12_S17_V0.5981.00
46_F51_V0.5971.00
6_L57_A0.5961.00
6_L42_V0.5951.00
11_M16_C0.5781.00
55_D59_A0.5761.00
11_M37_L0.5761.00
24_V44_V0.5741.00
14_Q36_N0.5661.00
34_H43_D0.5591.00
33_V37_L0.5471.00
29_G51_V0.5471.00
22_T25_G0.5410.99
57_A66_D0.5380.99
39_A43_D0.5270.99
59_A62_D0.5180.99
17_V35_V0.5170.99
19_A65_Y0.5120.99
34_H45_S0.5070.99
11_M35_V0.5020.99
17_V42_V0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ropA 1 1 99.4 0.209 Contact Map
2qifA 2 1 99.4 0.214 Contact Map
4u9rA 1 0.942 99.4 0.219 Contact Map
3dxsX 1 1 99.4 0.219 Contact Map
1p6tA 1 1 99.4 0.219 Contact Map
2g9oA 1 1 99.4 0.225 Contact Map
2ofgX 1 1 99.4 0.228 Contact Map
2l3mA 1 0.9855 99.4 0.228 Contact Map
2ldiA 1 1 99.4 0.231 Contact Map
1y3jA 1 1 99.4 0.231 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0045 seconds.