COPA - BACSU - GREMLIN Contacts

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COPA - Copper-exporting P-type ATPase A

UniProt:	O32220	Sequences: MSEQKEIAMQVSGMTCAACAARIEKGLKRMPGVTDANVNLATETSNVIYDPAETGTAAIQEKIEKLGYHVVTEKAEFDIEGMTCAACANRIEKRLNKIEGVANAPVNFALETVTVEYNPKEASVSDLKEAVDKLGYKLKLKGEQDSEAAAKKKEERKQTARLIFSAVLSFPLLWAMVSHFTFTSFIWVPDIFLNPWMQFALATPVQFLIGWPFYVGAYKALRNKSANMDVLVALGTTAAYAYSLYLTFQSIGSHGHTDGLYYETSAILLTLILLGKLFETKAKGRSSDAIKKLMKLQAKTATVVRDGQEQIIPIDEVLVNDIVYVKPGERIPVDGEVVEGRSAVDESMITGESLPVDKNPGDSVTGSTVNANGFLKIKAVNVGKDTALSHIIKIVEEAQGSKAPIQRLADQISGIFVPIVLGIAVLTFLIWYLWAAPGDFAEAISKFIAVLVIACPCALGLATPTSIMAGSGRAAEFGILFKGGEHLEKTHRLDTIVLDKTGTVTNGKPRLTDAIPFGRFEEKDLLQFAAAAETGSEHPLGEAIIAGVKDKGLEIPKLTRFEAKVGAGILAEAGGKSILVGTRKLMESEQVEHGALLAQMEELEAEGKTVMLVSIDGEAAGLVAVADTIKDTSRKAVARLKELGLDVIMMTGDNRRTAEAIAKEAGIANIIAEVLPEQKAAEIARLQKEGRQTAMVGDGINDAPALATADIGMAIGTGTDIAMETADITLIRGDLNSIADAIRMSRLTMKNIKQNLFWALGYNSLGIPIAALGFLAPWIAGAAMAFSSVSVVLNALRLQKVK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	802 (711)
Sequences:	10424 (6917)
Seq/√Len:	259.4

ECOLI - COPA ATZN
BACSU - COPA CADA ZOSA
HALSA - Q9HRH2 Q9HN90 Q9HSN5
SULSO - Q97VH4 Q97UU7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
655_R	659_E	4.819	1.00
203_T	240_Y	4.171	1.00
532_A	571_A	3.934	1.00
342_S	375_L	3.869	1.00
336_E	378_K	3.853	1.00
682_E	685_R	3.676	1.00
562_E	570_L	3.635	1.00
576_K	616_D	3.385	1.00
494_D	691_R	3.361	1.00
646_D	669_N	3.328	1.00
632_T	734_D	3.298	1.00
615_I	620_A	3.283	1.00
567_A	588_S	3.251	1.00
655_R	673_E	3.239	1.00
687_Q	708_T	3.148	1.00
678_Q	681_A	3.109	1.00
513_D	608_K	3.088	1.00
493_L	694_A	3.081	1.00
305_R	310_Q	3.027	1.00
651_T	658_A	3.026	1.00
560_R	572_E	3.007	1.00
322_I	376_K	2.995	1.00
300_T	311_I	2.931	1.00
531_A	556_P	2.902	1.00
339_E	376_K	2.898	1.00
322_I	338_V	2.796	1.00
302_T	311_I	2.794	1.00
80_E	137_K	2.690	1.00
303_V	310_Q	2.632	1.00
333_V	379_A	2.572	1.00
342_S	370_N	2.566	1.00
525_L	621_G	2.561	1.00
331_I	344_V	2.548	1.00
641_K	668_A	2.531	1.00
304_V	376_K	2.509	1.00
684_A	708_T	2.474	1.00
662_A	670_I	2.474	1.00
322_I	378_K	2.434	1.00
694_A	713_M	2.431	1.00
511_L	547_G	2.403	1.00
671_I	682_E	2.387	1.00
364_V	377_I	2.373	1.00
305_R	308_Q	2.354	1.00
579_L	589_E	2.329	1.00
511_L	623_V	2.320	1.00
659_E	663_K	2.312	1.00
506_N	628_T	2.299	1.00
302_T	329_E	2.296	1.00
169_S	270_T	2.282	1.00
634_R	638_A	2.242	1.00
247_T	262_Y	2.235	1.00
564_K	585_L	2.210	1.00
547_G	551_K	2.209	1.00
504_V	665_A	2.208	1.00
646_D	691_R	2.205	1.00
522_E	551_K	2.199	1.00
570_L	577_S	2.164	1.00
506_N	631_D	2.141	1.00
643_L	743_R	2.130	1.00
474_A	744_M	2.129	1.00
337_V	375_L	2.113	1.00
317_V	333_V	2.105	1.00
578_I	615_I	2.062	1.00
576_K	615_I	2.039	1.00
338_V	378_K	2.033	1.00
580_V	613_V	2.027	1.00
599_Q	602_E	2.017	1.00
215_V	219_K	2.011	1.00
751_N	797_R	1.962	1.00
586_M	614_S	1.960	1.00
428_F	447_F	1.944	1.00
528_F	578_I	1.925	1.00
497_V	683_I	1.918	1.00
359_N	362_D	1.913	1.00
237_T	241_A	1.910	1.00
600_M	612_L	1.906	1.00
636_A	739_A	1.874	1.00
303_V	312_I	1.869	1.00
757_F	761_G	1.868	1.00
641_K	647_V	1.837	1.00
422_G	426_L	1.832	1.00
427_T	446_K	1.832	1.00
610_V	622_L	1.822	1.00
317_V	323_V	1.816	1.00
88_A	108_F	1.813	1.00
211_W	215_V	1.810	1.00
659_E	670_I	1.808	1.00
687_Q	710_D	1.806	1.00
494_D	692_Q	1.793	1.00
128_K	138_L	1.778	1.00
635_K	736_N	1.777	1.00
84_C	87_C	1.769	1.00
717_T	733_G	1.765	1.00
530_A	548_V	1.762	1.00
214_Y	237_T	1.758	1.00
497_V	686_L	1.756	1.00
393_K	397_E	1.744	1.00
495_T	648_I	1.736	1.00
497_V	650_M	1.730	1.00
611_M	625_V	1.723	1.00
685_R	689_E	1.716	1.00
638_A	642_E	1.714	1.00
612_L	619_A	1.713	1.00
613_V	621_G	1.711	1.00
512_T	608_K	1.705	1.00
650_M	682_E	1.701	1.00
165_S	209_I	1.699	1.00
309_E	324_Y	1.699	1.00
129_E	133_K	1.698	1.00
411_Q	415_I	1.688	1.00
304_V	309_E	1.685	1.00
123_S	126_D	1.682	1.00
681_A	684_A	1.679	1.00
649_M	658_A	1.678	1.00
639_R	743_R	1.678	1.00
305_R	321_D	1.677	1.00
629_I	665_A	1.675	1.00
529_A	613_V	1.667	1.00
637_V	647_V	1.662	1.00
648_I	669_N	1.654	1.00
303_V	321_D	1.641	1.00
586_M	591_V	1.636	1.00
582_T	585_L	1.631	1.00
337_V	344_V	1.611	1.00
520_F	620_A	1.608	1.00
632_T	736_N	1.607	1.00
602_E	606_E	1.592	1.00
570_L	579_L	1.588	1.00
132_D	137_K	1.579	1.00
336_E	380_V	1.577	1.00
495_T	691_R	1.570	1.00
680_A	708_T	1.565	1.00
477_F	740_D	1.565	1.00
496_I	694_A	1.564	1.00
103_N	116_E	1.559	1.00
335_G	377_I	1.558	1.00
634_R	664_E	1.558	1.00
324_Y	376_K	1.554	1.00
379_A	382_V	1.552	1.00
320_N	378_K	1.533	1.00
473_R	477_F	1.533	1.00
206_Q	214_Y	1.529	1.00
751_N	795_A	1.526	1.00
671_I	685_R	1.524	1.00
527_Q	574_G	1.519	1.00
537_E	563_A	1.516	1.00
466_S	795_A	1.515	1.00
349_I	365_T	1.513	1.00
531_A	555_I	1.511	1.00
166_A	270_T	1.502	1.00
161_R	212_P	1.501	1.00
578_I	620_A	1.499	1.00
527_Q	556_P	1.498	1.00
542_E	546_A	1.496	1.00
199_F	244_L	1.495	1.00
635_K	639_R	1.488	1.00
173_L	267_I	1.487	1.00
547_G	550_D	1.479	1.00
234_L	421_L	1.478	1.00
302_T	309_E	1.476	1.00
564_K	570_L	1.468	1.00
337_V	340_G	1.465	1.00
233_A	237_T	1.463	1.00
336_E	361_G	1.463	1.00
572_E	577_S	1.453	1.00
684_A	688_K	1.449	1.00
423_I	771_A	1.447	1.00
341_R	357_D	1.445	1.00
579_L	585_L	1.445	1.00
430_I	434_W	1.441	1.00
346_E	358_K	1.436	1.00
470_G	748_T	1.435	1.00
492_R	692_Q	1.435	1.00
323_V	377_I	1.435	1.00
684_A	687_Q	1.434	1.00
363_S	380_V	1.433	1.00
524_D	527_Q	1.432	1.00
506_N	510_R	1.432	1.00
510_R	546_A	1.427	1.00
556_P	574_G	1.425	1.00
214_Y	233_A	1.421	1.00
498_L	504_V	1.410	1.00
533_E	541_G	1.408	1.00
301_A	332_P	1.408	1.00
523_K	551_K	1.408	1.00
343_A	357_D	1.405	1.00
341_R	359_N	1.403	1.00
651_T	672_A	1.400	1.00
325_V	377_I	1.398	1.00
363_S	381_N	1.397	1.00
344_V	375_L	1.390	1.00
345_D	371_A	1.386	1.00
544_I	623_V	1.378	1.00
732_R	737_S	1.378	1.00
510_R	628_T	1.372	1.00
509_P	540_L	1.371	1.00
603_L	624_A	1.363	1.00
583_R	587_E	1.359	1.00
532_A	578_I	1.355	1.00
561_F	569_I	1.353	1.00
583_R	612_L	1.349	1.00
713_M	738_I	1.348	1.00
428_F	432_Y	1.345	1.00
162_L	274_L	1.344	1.00
118_N	121_E	1.341	1.00
579_L	614_S	1.335	1.00
646_D	668_A	1.330	1.00
95_L	113_V	1.328	1.00
512_T	626_A	1.323	1.00
504_V	629_I	1.322	1.00
558_L	571_A	1.313	1.00
578_I	613_V	1.310	1.00
516_P	621_G	1.309	1.00
261_Y	264_T	1.304	1.00
95_L	127_L	1.303	1.00
498_L	647_V	1.300	1.00
324_Y	374_F	1.298	1.00
126_D	129_E	1.298	1.00
323_V	379_A	1.296	1.00
75_A	117_Y	1.292	1.00
632_T	636_A	1.288	1.00
516_P	525_L	1.288	1.00
304_V	324_Y	1.279	1.00
608_K	624_A	1.279	1.00
605_A	656_R	1.273	1.00
481_F	728_I	1.272	1.00
754_Q	794_N	1.266	1.00
521_E	524_D	1.260	1.00
130_A	134_L	1.256	1.00
681_A	685_R	1.256	1.00
629_I	661_I	1.255	1.00
517_F	596_L	1.253	1.00
532_A	569_I	1.253	1.00
374_F	535_G	1.251	1.00
511_L	625_V	1.249	1.00
92_E	96_N	1.247	1.00
426_L	430_I	1.245	1.00
643_L	746_R	1.245	1.00
383_G	386_T	1.241	1.00
102_A	116_E	1.238	1.00
313_P	316_E	1.231	1.00
534_T	549_K	1.230	1.00
473_R	476_E	1.229	1.00
96_N	104_A	1.228	1.00
669_N	689_E	1.224	1.00
527_Q	531_A	1.223	1.00
564_K	567_A	1.223	1.00
95_L	104_A	1.222	1.00
531_A	558_L	1.222	1.00
529_A	623_V	1.220	1.00
336_E	363_S	1.216	1.00
658_A	670_I	1.216	1.00
507_G	627_D	1.215	1.00
432_Y	440_F	1.213	1.00
530_A	555_I	1.208	1.00
558_L	573_A	1.195	1.00
466_S	751_N	1.192	1.00
96_N	103_N	1.189	1.00
98_I	130_A	1.187	1.00
573_A	578_I	1.185	1.00
749_M	753_K	1.184	1.00
532_A	580_V	1.174	1.00
579_L	591_V	1.172	1.00
520_F	525_L	1.169	1.00
515_I	603_L	1.165	1.00
302_T	326_K	1.160	1.00
546_A	549_K	1.159	1.00
591_V	614_S	1.159	1.00
206_Q	265_S	1.157	1.00
106_V	113_V	1.153	1.00
339_E	360_P	1.153	1.00
76_E	112_T	1.153	1.00
128_K	132_D	1.152	1.00
205_V	266_A	1.149	1.00
567_A	675_L	1.145	1.00
337_V	362_D	1.145	1.00
559_T	572_E	1.142	1.00
101_V	127_L	1.141	1.00
415_I	419_I	1.138	1.00
707_A	725_T	1.131	1.00
129_E	132_D	1.125	1.00
591_V	619_A	1.122	1.00
515_I	599_Q	1.121	1.00
304_V	322_I	1.118	1.00
491_H	749_M	1.116	1.00
218_Y	222_R	1.113	1.00
674_V	678_Q	1.109	1.00
80_E	139_K	1.107	1.00
558_L	561_F	1.105	1.00
639_R	643_L	1.103	1.00
421_L	425_V	1.102	1.00
596_L	619_A	1.100	1.00
490_T	711_I	1.099	1.00
650_M	674_V	1.098	1.00
439_D	442_E	1.098	1.00
162_L	166_A	1.095	1.00
559_T	575_G	1.094	1.00
281_K	285_R	1.094	1.00
514_A	547_G	1.093	1.00
516_P	522_E	1.090	1.00
490_T	741_A	1.089	1.00
794_N	797_R	1.087	1.00
518_G	618_E	1.085	1.00
581_G	585_L	1.078	1.00
79_I	82_M	1.076	1.00
601_E	605_A	1.071	1.00
573_A	576_K	1.071	1.00
525_L	613_V	1.071	1.00
210_G	269_L	1.070	1.00
303_V	323_V	1.067	1.00
331_I	364_V	1.065	1.00
327_P	342_S	1.062	1.00
529_A	580_V	1.062	1.00
567_A	584_K	1.059	1.00
163_I	167_V	1.055	1.00
348_M	368_T	1.053	1.00
78_D	141_K	1.047	1.00
662_A	667_I	1.047	1.00
167_V	171_P	1.043	1.00
597_L	601_E	1.041	1.00
206_Q	237_T	1.041	1.00
639_R	642_E	1.039	1.00
327_P	563_A	1.037	1.00
312_I	316_E	1.036	1.00
517_F	619_A	1.034	1.00
514_A	623_V	1.034	1.00
311_I	329_E	1.033	1.00
292_K	476_E	1.032	1.00
643_L	742_I	1.030	1.00
157_K	161_R	1.028	1.00
364_V	375_L	1.026	1.00
432_Y	443_A	1.025	1.00
102_A	118_N	1.025	1.00
440_F	444_I	1.024	1.00
76_E	114_T	1.022	1.00
781_G	785_A	1.021	1.00
327_P	370_N	1.021	1.00
579_L	586_M	1.020	1.00
489_K	692_Q	1.019	1.00
172_L	202_A	1.017	1.00
77_F	138_L	1.017	1.00
747_L	750_K	1.014	1.00
95_L	98_I	1.012	1.00
655_R	672_A	1.011	1.00
751_N	754_Q	1.009	1.00
677_E	681_A	1.009	1.00
570_L	589_E	1.009	1.00
635_K	638_A	1.007	1.00
94_R	134_L	1.007	1.00
498_L	738_I	1.006	1.00
323_V	333_V	1.006	1.00
199_F	240_Y	1.006	1.00
603_L	608_K	1.004	1.00
508_K	546_A	1.003	1.00
526_L	547_G	1.000	1.00
319_V	382_V	0.996	1.00
91_I	134_L	0.995	1.00
655_R	670_I	0.994	1.00
742_I	746_R	0.992	1.00
112_T	396_E	0.991	1.00
490_T	742_I	0.991	1.00
671_I	674_V	0.990	1.00
639_R	736_N	0.988	1.00
540_L	625_V	0.987	1.00
314_I	317_V	0.982	1.00
453_I	766_G	0.981	1.00
156_R	160_A	0.981	1.00
77_F	128_K	0.979	1.00
98_I	122_A	0.979	1.00
692_Q	710_D	0.974	1.00
643_L	739_A	0.972	1.00
493_L	692_Q	0.971	1.00
335_G	364_V	0.969	1.00
226_A	230_V	0.967	1.00
162_L	277_L	0.966	1.00
654_N	657_T	0.964	1.00
637_V	641_K	0.963	1.00
496_I	696_V	0.963	1.00
220_A	227_N	0.963	1.00
89_N	93_K	0.963	1.00
714_A	726_A	0.959	1.00
483_G	727_D	0.959	1.00
318_L	321_D	0.953	1.00
236_T	269_L	0.953	1.00
390_H	393_K	0.951	1.00
209_I	273_L	0.950	1.00
88_A	91_I	0.949	1.00
687_Q	693_T	0.949	1.00
240_Y	244_L	0.949	1.00
206_Q	236_T	0.948	1.00
532_A	613_V	0.947	1.00
489_K	492_R	0.945	1.00
513_D	624_A	0.944	1.00
429_L	433_L	0.942	1.00
292_K	721_I	0.939	1.00
98_I	127_L	0.939	1.00
172_L	266_A	0.937	1.00
79_I	113_V	0.936	1.00
317_V	379_A	0.936	1.00
305_R	312_I	0.935	1.00
494_D	690_G	0.935	1.00
648_I	682_E	0.934	1.00
344_V	364_V	0.930	1.00
516_P	519_R	0.930	1.00
530_A	545_I	0.930	1.00
217_A	226_A	0.929	1.00
390_H	677_E	0.929	1.00
654_N	673_E	0.924	1.00
82_M	87_C	0.924	1.00
504_V	637_V	0.924	1.00
325_V	331_I	0.923	1.00
555_I	558_L	0.922	1.00
527_Q	553_L	0.922	1.00
685_R	688_K	0.921	1.00
584_K	673_E	0.919	1.00
706_L	722_A	0.919	1.00
75_A	124_V	0.919	1.00
696_V	738_I	0.917	1.00
323_V	332_P	0.916	1.00
326_K	329_E	0.915	1.00
650_M	671_I	0.915	1.00
286_S	472_G	0.915	1.00
332_P	377_I	0.914	1.00
496_I	645_L	0.914	1.00
649_M	667_I	0.913	1.00
303_V	317_V	0.913	1.00
220_A	230_V	0.912	1.00
194_N	198_Q	0.911	1.00
337_V	342_S	0.911	1.00
122_A	126_D	0.910	1.00
534_T	555_I	0.909	1.00
638_A	641_K	0.907	1.00
766_G	779_I	0.906	1.00
789_V	793_L	0.906	1.00
169_S	205_V	0.903	1.00
176_M	179_H	0.902	1.00
204_P	208_L	0.900	1.00
331_I	375_L	0.900	1.00
195_P	260_L	0.899	1.00
268_L	781_G	0.897	1.00
366_G	386_T	0.893	1.00
617_G	620_A	0.891	1.00
430_I	773_G	0.887	1.00
528_F	615_I	0.886	1.00
583_R	604_E	0.885	1.00
531_A	557_K	0.884	1.00
156_R	159_T	0.883	1.00
639_R	739_A	0.883	1.00
79_I	138_L	0.882	1.00
245_Y	249_Q	0.882	1.00
128_K	140_L	0.880	1.00
382_V	385_D	0.877	1.00
632_T	635_K	0.877	1.00
737_S	740_D	0.876	1.00
327_P	537_E	0.876	1.00
427_T	450_V	0.874	1.00
599_Q	603_L	0.873	1.00
583_R	597_L	0.872	1.00
155_E	159_T	0.872	1.00
513_D	606_E	0.871	1.00
160_A	164_F	0.870	1.00
491_H	745_S	0.870	1.00
680_A	684_A	0.869	1.00
516_P	520_F	0.868	1.00
537_E	561_F	0.866	1.00
92_E	402_K	0.866	1.00
504_V	649_M	0.866	1.00
629_I	634_R	0.865	1.00
489_K	710_D	0.864	1.00
645_L	742_I	0.863	1.00
651_T	670_I	0.862	1.00
498_L	640_L	0.862	1.00
600_M	604_E	0.861	1.00
524_D	576_K	0.857	1.00
602_E	605_A	0.853	0.99
446_K	449_A	0.851	0.99
586_M	589_E	0.849	0.99
381_N	385_D	0.849	0.99
365_T	368_T	0.844	0.99
412_I	760_L	0.843	0.99
513_D	603_L	0.843	0.99
579_L	617_G	0.842	0.99
517_F	520_F	0.842	0.99
214_Y	236_T	0.842	0.99
747_L	751_N	0.841	0.99
159_T	163_I	0.841	0.99
515_I	622_L	0.841	0.99
512_T	624_A	0.840	0.99
512_T	603_L	0.839	0.99
523_K	553_L	0.838	0.99
442_E	446_K	0.837	0.99
353_S	657_T	0.837	0.99
639_R	740_D	0.835	0.99
131_V	138_L	0.831	0.99
514_A	526_L	0.830	0.99
763_N	784_M	0.830	0.99
673_E	678_Q	0.829	0.99
683_I	695_M	0.828	0.99
761_G	765_L	0.826	0.99
343_A	372_N	0.826	0.99
112_T	141_K	0.825	0.99
497_V	674_V	0.824	0.99
490_T	728_I	0.823	0.99
495_T	646_D	0.823	0.99
496_I	647_V	0.822	0.99
176_M	198_Q	0.822	0.99
338_V	360_P	0.821	0.99
714_A	718_G	0.821	0.99
341_R	560_R	0.820	0.99
420_V	767_I	0.817	0.99
104_A	113_V	0.817	0.99
407_R	411_Q	0.817	0.99
331_I	377_I	0.816	0.99
128_K	137_K	0.815	0.99
346_E	368_T	0.815	0.99
530_A	553_L	0.815	0.99
547_G	553_L	0.813	0.99
349_I	387_A	0.813	0.99
466_S	748_T	0.813	0.99
483_G	486_H	0.812	0.99
288_D	291_K	0.812	0.99
358_K	362_D	0.811	0.99
325_V	332_P	0.810	0.99
78_D	139_K	0.809	0.99
533_E	580_V	0.807	0.99
598_A	601_E	0.805	0.99
531_A	573_A	0.804	0.99
490_T	493_L	0.803	0.99
557_K	574_G	0.803	0.99
493_L	742_I	0.802	0.99
200_A	204_P	0.802	0.99
199_F	203_T	0.799	0.99
217_A	230_V	0.799	0.99
219_K	222_R	0.798	0.99
94_R	98_I	0.797	0.99
586_M	590_Q	0.797	0.99
428_F	443_A	0.796	0.99
381_N	390_H	0.795	0.99
728_I	741_A	0.794	0.99
210_G	236_T	0.791	0.99
244_L	247_T	0.791	0.99
633_S	636_A	0.788	0.99
525_L	529_A	0.787	0.99
294_M	723_M	0.786	0.99
524_D	528_F	0.785	0.99
786_F	790_S	0.785	0.99
431_W	443_A	0.785	0.99
285_R	288_D	0.784	0.99
546_A	550_D	0.784	0.99
382_V	386_T	0.784	0.99
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372_N	565_V	0.782	0.99
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301_A	317_V	0.781	0.99
633_S	637_V	0.781	0.99
329_E	537_E	0.780	0.99
630_K	733_G	0.778	0.99
636_A	735_L	0.778	0.99
428_F	440_F	0.778	0.99
366_G	387_A	0.777	0.99
485_E	489_K	0.777	0.99
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715_I	718_G	0.773	0.99
594_G	597_L	0.773	0.99
230_V	421_L	0.772	0.99
295_K	299_K	0.772	0.99
341_R	360_P	0.771	0.99
600_M	610_V	0.769	0.99
82_M	91_I	0.768	0.99
750_K	754_Q	0.768	0.99
94_R	130_A	0.768	0.99
221_L	230_V	0.768	0.99
113_V	131_V	0.766	0.99
513_D	522_E	0.766	0.99
172_L	176_M	0.765	0.99
604_E	656_R	0.763	0.99
658_A	672_A	0.761	0.99
372_N	562_E	0.761	0.99
165_S	273_L	0.761	0.99
288_D	292_K	0.760	0.99
528_F	620_A	0.759	0.99
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636_A	736_N	0.755	0.99
527_Q	554_E	0.755	0.99
321_D	333_V	0.753	0.99
260_L	264_T	0.751	0.99
323_V	335_G	0.748	0.99
661_I	664_E	0.748	0.99
202_A	266_A	0.746	0.99
124_V	140_L	0.745	0.99
504_V	633_S	0.745	0.99
793_L	797_R	0.744	0.99
227_N	230_V	0.742	0.99
612_L	622_L	0.741	0.99
766_G	769_I	0.741	0.99
429_L	432_Y	0.741	0.99
371_A	542_E	0.741	0.99
337_V	364_V	0.741	0.99
264_T	268_L	0.740	0.99
424_A	447_F	0.739	0.99
372_N	563_A	0.739	0.99
678_Q	682_E	0.737	0.99
660_A	664_E	0.737	0.99
387_A	677_E	0.737	0.99
626_A	664_E	0.736	0.99
165_S	270_T	0.736	0.99
267_I	778_W	0.735	0.99
657_T	660_A	0.733	0.98
304_V	307_G	0.733	0.98
82_M	106_V	0.733	0.98
585_L	589_E	0.733	0.98
587_E	597_L	0.732	0.98
169_S	173_L	0.732	0.98
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615_I	618_E	0.731	0.98
606_E	664_E	0.731	0.98
584_K	587_E	0.731	0.98
601_E	604_E	0.729	0.98
427_T	447_F	0.728	0.98
586_M	612_L	0.727	0.98
217_A	222_R	0.726	0.98
292_K	295_K	0.724	0.98
80_E	111_E	0.724	0.98
387_A	391_I	0.723	0.98
760_L	764_S	0.723	0.98
161_R	165_S	0.723	0.98
299_K	330_R	0.722	0.98
520_F	524_D	0.722	0.98
204_P	207_F	0.720	0.98
784_M	787_S	0.720	0.98
577_S	617_G	0.718	0.98
344_V	368_T	0.718	0.98
542_E	545_I	0.718	0.98
300_T	313_P	0.718	0.98
169_S	176_M	0.717	0.98
340_G	373_G	0.717	0.98
335_G	380_V	0.717	0.98
260_L	263_E	0.717	0.98
422_G	425_V	0.716	0.98
641_K	646_D	0.716	0.98
470_G	744_M	0.715	0.98
647_V	667_I	0.715	0.98
192_F	195_P	0.715	0.98
719_T	723_M	0.715	0.98
125_S	129_E	0.714	0.98
463_T	752_I	0.712	0.98
117_Y	127_L	0.712	0.98
155_E	277_L	0.711	0.98
195_P	198_Q	0.710	0.98
100_G	118_N	0.710	0.98
467_I	488_E	0.710	0.98
493_L	496_I	0.708	0.98
164_F	209_I	0.708	0.98
495_T	686_L	0.707	0.98
525_L	620_A	0.707	0.98
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745_S	749_M	0.706	0.98
683_I	693_T	0.704	0.98
196_W	248_F	0.704	0.98
493_L	645_L	0.704	0.98
424_A	451_L	0.701	0.98
766_G	783_A	0.701	0.98
469_A	799_Q	0.699	0.98
161_R	211_W	0.698	0.98
191_I	195_P	0.698	0.98
343_A	371_A	0.698	0.98
430_I	433_L	0.697	0.98
424_A	428_F	0.696	0.98
216_G	229_D	0.695	0.98
407_R	488_E	0.695	0.98
158_Q	273_L	0.695	0.98
117_Y	121_E	0.695	0.98
514_A	529_A	0.694	0.98
592_E	595_A	0.694	0.98
496_I	742_I	0.692	0.98
344_V	358_K	0.692	0.98
166_A	274_L	0.691	0.98
99_E	121_E	0.691	0.98
613_V	623_V	0.690	0.98
754_Q	797_R	0.689	0.98
310_Q	321_D	0.689	0.98
317_V	321_D	0.689	0.98
769_I	779_I	0.688	0.98
115_V	127_L	0.684	0.98
650_M	683_I	0.684	0.98
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302_T	324_Y	0.683	0.98
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476_E	799_Q	0.682	0.98
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319_V	385_D	0.679	0.97
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309_E	326_K	0.677	0.97
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631_D	664_E	0.670	0.97
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498_L	696_V	0.669	0.97
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648_I	671_I	0.665	0.97
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333_V	366_G	0.655	0.97
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284_G	287_S	0.645	0.97
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159_T	277_L	0.645	0.97
294_M	392_I	0.643	0.97
479_I	740_D	0.642	0.96
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548_V	555_I	0.641	0.96
616_D	620_A	0.641	0.96
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393_K	396_E	0.639	0.96
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675_L	678_Q	0.639	0.96
240_Y	265_S	0.638	0.96
769_I	774_F	0.638	0.96
322_I	339_E	0.637	0.96
665_A	735_L	0.637	0.96
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277_L	281_K	0.635	0.96
733_G	737_S	0.635	0.96
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739_A	743_R	0.633	0.96
494_D	646_D	0.632	0.96
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168_L	171_P	0.630	0.96
276_K	283_K	0.629	0.96
674_V	680_A	0.628	0.96
490_T	694_A	0.627	0.96
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303_V	318_L	0.627	0.96
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381_N	387_A	0.627	0.96
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165_S	169_S	0.626	0.96
340_G	375_L	0.626	0.96
117_Y	124_V	0.625	0.96
274_L	278_F	0.625	0.96
583_R	600_M	0.624	0.96
494_D	497_V	0.624	0.96
498_L	633_S	0.624	0.96
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83_T	108_F	0.624	0.96
339_E	557_K	0.622	0.96
119_P	122_A	0.622	0.96
776_A	779_I	0.621	0.96
122_A	127_L	0.619	0.96
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193_L	196_W	0.617	0.96
518_G	521_E	0.617	0.96
517_F	622_L	0.617	0.96
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549_K	555_I	0.615	0.96
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309_E	376_K	0.614	0.96
730_L	738_I	0.614	0.96
694_A	711_I	0.614	0.96
235_G	238_A	0.613	0.95
330_R	345_D	0.613	0.95
236_T	781_G	0.612	0.95
640_L	645_L	0.611	0.95
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401_S	485_E	0.591	0.94
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419_I	423_I	0.583	0.94
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552_G	555_I	0.580	0.94
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321_D	379_A	0.577	0.94
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529_A	547_G	0.575	0.94
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582_T	612_L	0.574	0.94
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163_I	166_A	0.572	0.93
510_R	547_G	0.571	0.93
337_V	360_P	0.571	0.93
403_A	483_G	0.570	0.93
170_F	173_L	0.570	0.93
762_Y	784_M	0.570	0.93
535_G	558_L	0.569	0.93
153_K	156_R	0.569	0.93
314_I	333_V	0.569	0.93
650_M	695_M	0.569	0.93
90_R	93_K	0.568	0.93
491_H	753_K	0.568	0.93
168_L	205_V	0.567	0.93
489_K	711_I	0.567	0.93
762_Y	790_S	0.566	0.93
166_A	173_L	0.566	0.93
497_V	682_E	0.565	0.93
391_I	700_I	0.564	0.93
85_A	88_A	0.564	0.93
777_P	784_M	0.564	0.93
333_V	383_G	0.564	0.93
207_F	240_Y	0.563	0.93
110_L	396_E	0.562	0.93
416_F	457_C	0.562	0.93
246_L	259_G	0.562	0.93
267_I	271_L	0.561	0.93
536_S	563_A	0.560	0.93
169_S	267_I	0.560	0.93
345_D	508_K	0.559	0.93
330_R	369_V	0.559	0.93
766_G	775_L	0.559	0.93
85_A	108_F	0.557	0.93
528_F	573_A	0.557	0.93
354_L	357_D	0.557	0.93
420_V	457_C	0.556	0.93
496_I	637_V	0.556	0.93
202_A	206_Q	0.554	0.92
221_L	224_K	0.554	0.92
535_G	545_I	0.554	0.92
636_A	734_D	0.554	0.92
195_P	199_F	0.554	0.92
218_Y	230_V	0.554	0.92
160_A	163_I	0.554	0.92
77_F	131_V	0.554	0.92
416_F	420_V	0.553	0.92
761_G	764_S	0.553	0.92
630_K	717_T	0.552	0.92
113_V	138_L	0.552	0.92
405_I	749_M	0.551	0.92
560_R	570_L	0.551	0.92
299_K	315_D	0.551	0.92
269_L	273_L	0.551	0.92
169_S	266_A	0.550	0.92
312_I	317_V	0.549	0.92
343_A	354_L	0.549	0.92
519_R	522_E	0.547	0.92
586_M	619_A	0.545	0.92
531_A	553_L	0.545	0.92
419_I	422_G	0.544	0.92
712_G	725_T	0.544	0.92
748_T	794_N	0.543	0.92
278_F	465_T	0.543	0.92
516_P	521_E	0.543	0.92
198_Q	202_A	0.543	0.92
734_D	737_S	0.543	0.92
165_S	173_L	0.542	0.92
177_V	778_W	0.540	0.91
111_E	283_K	0.540	0.91
86_A	90_R	0.540	0.91
470_G	487_L	0.540	0.91
242_Y	246_L	0.539	0.91
604_E	654_N	0.539	0.91
527_Q	555_I	0.538	0.91
735_L	738_I	0.538	0.91
206_Q	269_L	0.538	0.91
245_Y	250_S	0.537	0.91
715_I	729_T	0.537	0.91
444_I	448_I	0.537	0.91
413_S	488_E	0.537	0.91
379_A	383_G	0.537	0.91
384_K	389_S	0.537	0.91
496_I	713_M	0.536	0.91
312_I	333_V	0.535	0.91
303_V	309_E	0.535	0.91
340_G	360_P	0.534	0.91
368_T	386_T	0.534	0.91
633_S	665_A	0.534	0.91
587_E	590_Q	0.534	0.91
506_N	632_T	0.534	0.91
529_A	621_G	0.534	0.91
515_I	608_K	0.533	0.91
508_K	542_E	0.533	0.91
105_P	114_T	0.533	0.91
213_F	273_L	0.532	0.91
460_G	784_M	0.530	0.91
246_L	250_S	0.530	0.91
287_S	482_K	0.530	0.91
409_A	414_G	0.530	0.91
640_L	738_I	0.529	0.91
633_S	735_L	0.528	0.90
532_A	573_A	0.527	0.90
299_K	314_I	0.527	0.90
93_K	97_K	0.527	0.90
465_T	469_A	0.527	0.90
243_S	262_Y	0.526	0.90
344_V	373_G	0.526	0.90
282_A	469_A	0.525	0.90
494_D	693_T	0.524	0.90
82_M	108_F	0.524	0.90
434_W	438_G	0.524	0.90
466_S	470_G	0.523	0.90
101_V	104_A	0.523	0.90
649_M	661_I	0.523	0.90
535_G	561_F	0.523	0.90
730_L	737_S	0.522	0.90
782_A	786_F	0.522	0.90
98_I	126_D	0.521	0.90
383_G	389_S	0.520	0.90
423_I	767_I	0.519	0.90
432_Y	437_P	0.519	0.90
337_V	377_I	0.519	0.90
175_A	179_H	0.518	0.90
247_T	260_L	0.517	0.90
657_T	661_I	0.516	0.89
530_A	547_G	0.516	0.89
239_A	265_S	0.515	0.89
173_L	176_M	0.515	0.89
178_S	181_T	0.515	0.89
238_A	444_I	0.515	0.89
124_V	138_L	0.514	0.89
198_Q	260_L	0.514	0.89
603_L	610_V	0.514	0.89
94_R	131_V	0.514	0.89
228_M	455_C	0.512	0.89
506_N	509_P	0.512	0.89
374_F	561_F	0.511	0.89
244_L	262_Y	0.511	0.89
473_R	797_R	0.511	0.89
584_K	675_L	0.511	0.89
549_K	552_G	0.511	0.89
656_R	660_A	0.510	0.89
496_I	735_L	0.510	0.89
212_P	273_L	0.510	0.89
98_I	134_L	0.510	0.89
176_M	180_F	0.509	0.89
162_L	165_S	0.508	0.89
434_W	437_P	0.508	0.89
474_A	481_F	0.508	0.89
529_A	548_V	0.508	0.89
603_L	606_E	0.508	0.89
415_I	418_P	0.507	0.89
98_I	101_V	0.507	0.89
268_L	272_I	0.507	0.89
391_I	704_P	0.506	0.89
229_D	276_K	0.506	0.89
575_G	616_D	0.506	0.89
514_A	553_L	0.505	0.88
567_A	582_T	0.505	0.88
608_K	664_E	0.505	0.88
111_E	151_K	0.504	0.88
430_I	772_L	0.502	0.88
581_G	614_S	0.502	0.88
77_F	115_V	0.502	0.88
79_I	108_F	0.501	0.88
245_Y	252_G	0.501	0.88
407_R	410_D	0.501	0.88
161_R	164_F	0.500	0.88
384_K	393_K	0.500	0.88

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4bbjA	1	0.808	100	0.239	Contact Map
3j09A	2	0.8815	100	0.251	Contact Map
4umwA	1	0.7506	100	0.275	Contact Map
3j08A	2	0.7843	100	0.323	Contact Map
3b8cA	1	0.7706	100	0.507	Contact Map
1mhsA	2	0.8404	100	0.509	Contact Map
3ixzA	1	0.7968	100	0.525	Contact Map
2zxeA	1	0.7868	100	0.526	Contact Map
3ar4A	1	0.783	100	0.533	Contact Map
3skxA	1	0.3254	100	0.788	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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