GREMLIN Database
CADA - Cadmium, zinc and cobalt-transporting ATPase
UniProt: O32219 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 702 (558)
Sequences: 23838 (14023)
Seq/√Len: 593.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
396_K588_E4.2251.00
237_G279_I4.1291.00
549_K553_E3.9961.00
202_Y213_Q3.4421.00
238_K280_E3.4021.00
578_E605_R3.3061.00
395_V591_I3.2761.00
525_D632_Q3.2381.00
244_A277_L3.2211.00
241_Q278_H3.1231.00
539_K563_E2.9911.00
576_Q579_A2.9741.00
206_K278_H2.9621.00
581_E605_R2.9571.00
508_V513_A2.9401.00
463_E471_F2.8481.00
207_T212_E2.8391.00
204_N213_Q2.7821.00
545_T552_G2.7101.00
549_K567_E2.6641.00
572_D575_A2.6031.00
556_G564_V2.5861.00
461_S473_K2.5611.00
408_K524_E2.5471.00
434_A472_A2.5391.00
527_A531_A2.5301.00
224_I278_H2.5301.00
408_K521_E2.5241.00
477_T509_D2.5201.00
553_E557_K2.5041.00
565_Y576_Q2.4921.00
492_I495_V2.4781.00
379_A638_E2.4521.00
224_I240_V2.4471.00
211_I226_V2.4251.00
205_L212_E2.4121.00
207_T210_G2.3911.00
415_E501_G2.3631.00
244_A272_N2.3531.00
266_V279_I2.3501.00
235_L281_V2.3251.00
581_E607_D2.2791.00
591_I610_V2.2631.00
240_V280_E2.2571.00
531_A535_S2.2561.00
206_K211_I2.2171.00
204_N231_E2.2081.00
224_I280_E2.1891.00
468_H489_R2.1761.00
204_N211_I2.1731.00
532_D641_R2.1371.00
330_A349_A2.1321.00
413_V449_A2.1151.00
226_V278_H2.0431.00
427_L514_G2.0241.00
534_K562_G2.0201.00
133_I137_K1.9871.00
477_T508_V1.9221.00
536_L641_R1.9211.00
225_I237_G1.8981.00
539_K588_E1.8951.00
496_P517_I1.8691.00
433_Y457_D1.8461.00
237_G266_V1.8431.00
406_L559_L1.8361.00
415_E499_N1.8251.00
505_H512_Y1.8251.00
233_I246_V1.8051.00
528_Q532_D1.7991.00
430_A479_I1.7951.00
471_F478_E1.7911.00
544_L576_Q1.7881.00
238_K282_T1.7711.00
398_A591_I1.7651.00
399_V580_L1.7641.00
399_V544_L1.7611.00
479_I508_V1.7561.00
245_M259_K1.7461.00
522_I559_L1.7331.00
498_E550_Q1.7261.00
207_T223_D1.7181.00
578_E582_A1.7131.00
265_D282_T1.7121.00
413_V516_I1.7111.00
396_K589_K1.7061.00
579_A583_K1.6811.00
503_I515_A1.6671.00
239_V277_L1.6661.00
248_T260_A1.6591.00
487_M507_A1.6581.00
426_R429_E1.6571.00
376_A642_I1.6541.00
204_N228_N1.6441.00
649_I695_R1.6411.00
222_G280_E1.6311.00
449_A452_K1.6291.00
414_T519_A1.6261.00
225_I279_I1.6231.00
295_D299_N1.6211.00
574_V605_R1.6211.00
508_V511_R1.6161.00
544_L568_L1.6091.00
534_K541_T1.5941.00
219_V235_L1.5931.00
261_A264_Q1.5841.00
246_V272_N1.5831.00
444_E448_K1.5801.00
397_Y542_A1.5701.00
431_A506_V1.5611.00
152_A156_I1.5551.00
397_Y588_E1.5521.00
465_I486_L1.5461.00
205_L223_D1.5361.00
543_M552_G1.5331.00
221_T284_G1.5311.00
575_A578_E1.5221.00
529_A637_A1.5211.00
490_E494_D1.5191.00
501_G517_I1.5171.00
219_V281_V1.5131.00
313_K317_Y1.5121.00
480_L507_A1.5081.00
553_E564_V1.4931.00
494_D498_E1.4931.00
219_V225_I1.4891.00
202_Y215_S1.4851.00
375_A379_A1.4821.00
527_A558_Q1.4701.00
480_L510_Q1.4681.00
156_I160_L1.4661.00
214_V218_D1.4621.00
615_L631_D1.4611.00
394_Q589_K1.4551.00
528_Q634_S1.4491.00
542_A563_E1.4481.00
481_A506_V1.4471.00
575_A579_A1.4441.00
334_P342_L1.4411.00
471_F480_L1.4301.00
446_V516_I1.4281.00
679_V682_D1.4271.00
247_D273_Q1.4251.00
412_E448_K1.4211.00
251_L267_M1.4201.00
493_E505_H1.4201.00
265_D283_K1.4131.00
525_D634_S1.4081.00
215_S218_D1.4051.00
324_I328_L1.4021.00
630_T635_K1.3911.00
519_A558_Q1.3881.00
372_G646_T1.3871.00
495_V499_N1.3841.00
205_L214_V1.3831.00
225_I281_V1.3821.00
532_D535_S1.3781.00
480_L487_M1.3751.00
238_K265_D1.3741.00
426_R508_V1.3671.00
246_V277_L1.3671.00
333_P345_W1.3621.00
412_E521_E1.3611.00
417_K492_I1.3531.00
409_G520_D1.3531.00
237_G282_T1.3521.00
206_K226_V1.3491.00
473_K478_E1.3381.00
484_K488_E1.3331.00
491_Q495_V1.3321.00
579_A582_A1.3301.00
408_K412_E1.3131.00
341_A344_D1.3131.00
528_Q531_A1.3111.00
399_V577_V1.3051.00
655_G659_G1.3051.00
539_K542_A1.3031.00
243_S261_A1.2991.00
432_A450_Y1.2971.00
448_K452_K1.2961.00
243_S259_K1.2951.00
525_D528_Q1.2921.00
414_T501_G1.2901.00
565_Y579_A1.2881.00
583_K588_E1.2841.00
504_V518_I1.2831.00
465_I471_F1.2771.00
383_V626_I1.2751.00
483_N486_L1.2741.00
545_T566_A1.2731.00
610_V636_I1.2691.00
385_G625_D1.2661.00
578_E581_E1.2651.00
304_K312_T1.2631.00
422_F513_A1.2531.00
139_I142_G1.2501.00
283_K287_E1.2431.00
328_L332_V1.2411.00
603_L620_A1.2341.00
132_I152_A1.2311.00
429_E433_Y1.2201.00
589_K607_D1.2161.00
439_Q464_E1.2121.00
391_A589_K1.2121.00
226_V276_V1.2111.00
611_A624_A1.2071.00
484_K505_H1.2071.00
554_A558_Q1.1991.00
179_L183_A1.1961.00
491_Q494_D1.1961.00
480_L486_L1.1951.00
329_L348_R1.1931.00
331_F335_L1.1931.00
132_I156_I1.1921.00
647_R651_W1.1911.00
549_K566_A1.1871.00
284_G287_E1.1871.00
413_V518_I1.1821.00
220_Q223_D1.1741.00
228_N231_E1.1701.00
227_V233_I1.1671.00
494_D550_Q1.1661.00
552_G566_A1.1611.00
400_F541_T1.1591.00
462_Y470_I1.1591.00
330_A334_P1.1531.00
479_I513_A1.1531.00
431_A516_I1.1491.00
323_V327_V1.1441.00
410_S448_K1.1411.00
565_Y568_L1.1401.00
245_M274_N1.1371.00
538_I640_I1.1341.00
397_Y580_L1.1211.00
207_T214_V1.1211.00
246_V266_V1.1191.00
393_N647_R1.1181.00
415_E517_I1.1141.00
552_G564_V1.1081.00
532_D536_L1.1051.00
542_A580_L1.0971.00
496_P501_G1.0951.00
427_L431_A1.0951.00
292_K295_D1.0941.00
571_Q575_A1.0931.00
448_K451_G1.0891.00
682_D685_V1.0861.00
568_L572_D1.0841.00
183_A187_R1.0811.00
506_V514_G1.0791.00
423_T426_R1.0771.00
206_K224_I1.0761.00
238_K263_G1.0721.00
525_D529_A1.0691.00
536_L644_K1.0691.00
400_F406_L1.0681.00
435_E443_A1.0661.00
375_A378_K1.0611.00
239_V242_G1.0581.00
430_A513_A1.0531.00
640_I644_K1.0481.00
465_I468_H1.0481.00
227_V279_I1.0381.00
396_K587_S1.0371.00
136_V140_I1.0361.00
429_E475_N1.0321.00
289_A292_K1.0311.00
442_I518_I1.0301.00
391_A607_D1.0281.00
428_L449_A1.0251.00
493_E497_D1.0231.00
241_Q262_E1.0221.00
464_E469_G1.0181.00
652_Q692_N1.0141.00
292_K571_Q1.0131.00
418_P427_L1.0021.00
190_K193_S1.0021.00
507_A510_Q1.0011.00
225_I234_P1.0001.00
397_Y539_K0.9981.00
155_T171_M0.9971.00
430_A508_V0.9951.00
678_A682_D0.9951.00
418_P514_G0.9931.00
543_M561_I0.9921.00
460_E473_K0.9901.00
492_I496_P0.9871.00
675_M682_D0.9871.00
418_P424_K0.9841.00
233_I266_V0.9801.00
522_I555_V0.9791.00
479_I506_V0.9781.00
145_F149_F0.9691.00
309_N313_K0.9671.00
574_V578_E0.9671.00
406_L522_I0.9671.00
368_G649_I0.9671.00
281_V284_G0.9651.00
673_A678_A0.9651.00
392_L639_A0.9631.00
549_K564_V0.9611.00
420_E511_R0.9611.00
220_Q284_G0.9581.00
526_A530_V0.9571.00
675_M678_A0.9571.00
411_F442_I0.9561.00
675_M679_V0.9551.00
332_V336_V0.9541.00
203_A219_V0.9541.00
239_V246_V0.9511.00
269_G290_V0.9501.00
536_L637_A0.9461.00
381_V635_K0.9451.00
505_H515_A0.9431.00
533_L637_A0.9381.00
674_T677_E0.9371.00
392_L608_I0.9361.00
581_E590_L0.9331.00
153_L323_V0.9311.00
531_A534_K0.9311.00
538_I541_T0.9261.00
429_E457_D0.9251.00
548_S567_E0.9231.00
497_D550_Q0.9231.00
612_M616_G0.9191.00
395_V589_K0.9171.00
239_V266_V0.9161.00
417_K496_P0.9151.00
382_L629_M0.9141.00
151_M158_A0.9131.00
368_G693_A0.9111.00
419_A422_F0.9081.00
577_V592_F0.9061.00
645_R648_R0.9041.00
530_V534_K0.9041.00
484_K493_E0.8971.00
532_D637_A0.8941.00
692_N695_R0.8941.00
679_V684_G0.8941.00
393_N643_A0.8911.00
649_I652_Q0.8911.00
227_V272_N0.8891.00
415_E424_K0.8871.00
422_F427_L0.8851.00
398_A538_I0.8841.00
207_T220_Q0.8821.00
426_R430_A0.8811.00
482_G486_L0.8801.00
635_K638_E0.8801.00
355_I664_F0.8771.00
417_K515_A0.8761.00
248_T258_R0.8761.00
239_V279_I0.8731.00
187_R190_K0.8731.00
539_K562_G0.8711.00
604_A623_A0.8711.00
419_A512_Y0.8701.00
289_A571_Q0.8691.00
416_I516_I0.8691.00
532_D634_S0.8681.00
213_Q231_E0.8601.00
232_S271_I0.8581.00
276_V437_H0.8571.00
684_G688_L0.8571.00
159_F163_Q0.8571.00
649_I693_A0.8561.00
211_I278_H0.8561.00
682_D686_T0.8561.00
434_A470_I0.8521.00
434_A479_I0.8511.00
146_D149_F0.8501.00
485_K567_E0.8491.00
506_V516_I0.8491.00
687_L691_A0.8491.00
569_L572_D0.8481.00
380_G630_T0.8471.00
216_S219_V0.8471.00
260_A264_Q0.8461.00
536_L640_I0.8461.00
522_I527_A0.8431.00
311_I365_I0.8421.00
295_D298_Q0.8401.00
320_P324_I0.8401.00
677_E682_D0.8391.00
433_Y456_S0.8391.00
686_T689_A0.8371.00
248_T270_F0.8371.00
432_A456_S0.8361.00
427_L506_V0.8341.00
464_E467_G0.8321.00
415_E496_P0.8311.00
499_N558_Q0.8311.00
425_D429_E0.8311.00
468_H569_L0.8281.00
548_S551_T0.8281.00
563_E583_K0.8281.00
436_L451_G0.8271.00
233_I272_N0.8271.00
391_A394_Q0.8251.00
246_V260_A0.8251.00
250_A270_F0.8241.00
211_I228_N0.8231.00
679_V683_V0.8221.00
212_E218_D0.8201.00
267_M270_F0.8201.00
190_K194_A0.8191.00
251_L289_A0.8181.00
266_V277_L0.8181.00
285_Y288_S0.8171.00
392_L640_I0.8161.00
542_A576_Q0.8131.00
679_V686_T0.8131.00
330_A345_W0.8121.00
530_V561_I0.8111.00
530_V541_T0.8111.00
495_V498_E0.8091.00
544_L565_Y0.8071.00
385_G388_Y0.8031.00
194_A197_D0.8021.00
412_E452_K0.8011.00
433_Y459_I0.7991.00
205_L219_V0.7991.00
556_G561_I0.7981.00
487_M505_H0.7981.00
678_A686_T0.7971.00
682_D689_A0.7971.00
137_K140_I0.7911.00
416_I449_A0.7891.00
593_V636_I0.7881.00
135_A138_N0.7881.00
334_P345_W0.7851.00
399_V542_A0.7841.00
679_V689_A0.7811.00
429_E454_L0.7811.00
186_S190_K0.7801.00
541_T561_I0.7791.00
325_I669_A0.7791.00
205_L225_I0.7771.00
223_D281_V0.7741.00
428_L431_A0.7731.00
159_F162_Q0.7711.00
550_Q553_E0.7651.00
242_G262_E0.7641.00
240_V278_H0.7641.00
317_Y321_A0.7591.00
316_K320_P0.7581.00
459_I474_V0.7571.00
434_A481_A0.7541.00
466_S469_G0.7531.00
543_M556_G0.7521.00
526_A559_L0.7511.00
234_P279_I0.7511.00
468_H485_K0.7511.00
203_A234_P0.7501.00
151_M154_A0.7491.00
532_D638_E0.7491.00
529_A634_S0.7491.00
159_F167_G0.7491.00
432_A447_R0.7481.00
430_A434_A0.7481.00
542_A565_Y0.7441.00
519_A522_I0.7441.00
379_A641_R0.7431.00
201_D232_S0.7421.00
227_V234_P0.7411.00
134_R137_K0.7411.00
603_L609_G0.7411.00
678_A681_S0.7401.00
331_F334_P0.7371.00
383_V639_A0.7361.00
286_Q295_D0.7341.00
673_A677_E0.7341.00
490_E493_E0.7341.00
498_E553_E0.7321.00
279_I282_T0.7321.00
239_V264_Q0.7311.00
684_G689_A0.7311.00
551_T555_V0.7311.00
529_A633_P0.7291.00
583_K587_S0.7291.00
484_K497_D0.7271.00
345_W349_A0.7261.00
395_V640_I0.7251.00
203_A216_S0.7251.00
376_A383_V0.7241.00
225_I235_L0.7231.00
340_A344_D0.7221.00
239_V244_A0.7201.00
387_N391_A0.7201.00
229_P272_N0.7191.00
463_E466_S0.7181.00
551_T554_A0.7171.00
472_A480_L0.7161.00
678_A685_V0.7161.00
626_I639_A0.7161.00
680_F683_V0.7151.00
283_K292_K0.7141.00
673_A679_V0.7131.00
643_A647_R0.7121.00
638_E641_R0.7121.00
406_L526_A0.7111.00
418_P422_F0.7111.00
462_Y466_S0.7101.00
648_R652_Q0.7101.00
229_P464_E0.7091.00
418_P421_G0.7061.00
595_D598_N0.7061.00
193_S197_D0.7051.00
685_V689_A0.7021.00
327_V331_F0.7021.00
392_L395_V0.7011.00
459_I472_A0.7011.00
204_N226_V0.7001.00
406_L530_V0.6991.00
274_N463_E0.6991.00
496_P499_N0.6981.00
375_A642_I0.6971.00
512_Y515_A0.6961.00
396_K539_K0.6941.00
329_L669_A0.6941.00
342_L346_V0.6931.00
392_L626_I0.6931.00
450_Y454_L0.6901.00
545_T564_V0.6891.00
437_H444_E0.6891.00
398_A593_V0.6871.00
246_V270_F0.6871.00
652_Q695_R0.6871.00
459_I462_Y0.6861.00
182_G186_S0.6851.00
228_N276_V0.6851.00
611_A616_G0.6841.00
381_V639_A0.6831.00
380_G629_M0.6831.00
144_V178_E0.6821.00
188_S374_G0.6811.00
465_I469_G0.6801.00
493_E515_A0.6801.00
663_I667_L0.6781.00
430_A433_Y0.6781.00
645_R649_I0.6771.00
431_A481_A0.6771.00
194_A619_A0.6771.00
398_A541_T0.6771.00
137_K141_R0.6751.00
527_A559_L0.6741.00
154_A158_A0.6741.00
431_A435_E0.6731.00
554_A557_K0.6731.00
680_F684_G0.6721.00
255_S551_T0.6711.00
416_I428_L0.6701.00
400_F533_L0.6701.00
691_A695_R0.6701.00
252_T258_R0.6691.00
229_P244_A0.6671.00
679_V685_V0.6661.00
418_P423_T0.6661.00
151_M162_Q0.6651.00
493_E503_I0.6651.00
446_V518_I0.6641.00
463_E467_G0.6641.00
494_D497_D0.6631.00
444_E447_R0.6611.00
138_N146_D0.6611.00
664_F667_L0.6611.00
268_S288_S0.6601.00
197_D201_D0.6601.00
239_V260_A0.6591.00
455_S458_E0.6571.00
412_E519_A0.6571.00
675_M687_L0.6571.00
221_T283_K0.6571.00
422_F426_R0.6561.00
568_L576_Q0.6541.00
344_D348_R0.6501.00
414_T558_Q0.6491.00
686_T690_V0.6481.00
205_L220_Q0.6481.00
484_K490_E0.6481.00
304_K309_N0.6481.00
330_A342_L0.6471.00
284_G288_S0.6451.00
285_Y291_S0.6451.00
531_A560_G0.6441.00
618_D621_V0.6441.00
580_L583_K0.6431.00
201_D217_E0.6411.00
600_T623_A0.6381.00
461_S466_S0.6381.00
186_S189_R0.6381.00
496_P503_I0.6371.00
510_Q513_A0.6371.00
577_V590_L0.6371.00
675_M685_V0.6371.00
235_L288_S0.6371.00
395_V538_I0.6361.00
637_A641_R0.6361.00
497_D503_I0.6361.00
369_F390_E0.6331.00
398_A640_I0.6311.00
135_A140_I0.6311.00
170_V679_V0.6291.00
432_A454_L0.6291.00
434_A506_V0.6281.00
221_T287_E0.6281.00
399_V568_L0.6251.00
374_G378_K0.6251.00
677_E686_T0.6251.00
329_L349_A0.6251.00
681_S684_G0.6231.00
243_S262_E0.6211.00
162_Q165_P0.6181.00
675_M689_A0.6161.00
486_L489_R0.6161.00
410_S444_E0.6151.00
326_A353_L0.6131.00
243_S461_S0.6131.00
233_I277_L0.6131.00
414_T517_I0.6121.00
135_A145_F0.6091.00
314_F654_I0.6091.00
499_N557_K0.6081.00
239_V261_A0.6081.00
689_A692_N0.6081.00
526_A633_P0.6071.00
676_W679_V0.6071.00
675_M686_T0.6071.00
425_D454_L0.6061.00
433_Y436_L0.6051.00
420_E423_T0.6041.00
348_R351_I0.6031.00
496_P515_A0.6031.00
555_V558_Q0.6031.00
345_W348_R0.6031.00
449_A516_I0.6021.00
673_A682_D0.6011.00
431_A434_A0.6001.00
168_V172_L0.6001.00
151_M159_F0.6001.00
296_L571_Q0.6001.00
406_L543_M0.5991.00
240_V262_E0.5991.00
485_K488_E0.5991.00
675_M680_F0.5991.00
530_V559_L0.5981.00
245_M273_Q0.5961.00
135_A139_I0.5961.00
637_A640_I0.5961.00
242_G277_L0.5951.00
368_G646_T0.5951.00
395_V608_I0.5941.00
317_Y320_P0.5931.00
428_L450_Y0.5931.00
408_K525_D0.5911.00
664_F681_S0.5901.00
555_V559_L0.5881.00
398_A533_L0.5881.00
272_N277_L0.5871.00
533_L636_I0.5871.00
393_N644_K0.5861.00
478_E510_Q0.5861.00
227_V231_E0.5861.00
326_A330_A0.5841.00
632_Q635_K0.5841.00
313_K316_K0.5831.00
466_S470_I0.5831.00
138_N142_G0.5821.00
286_Q291_S0.5791.00
642_I645_R0.5791.00
206_K209_N0.5791.00
533_L538_I0.5781.00
675_M684_G0.5781.00
288_S291_S0.5781.00
673_A684_G0.5771.00
523_K631_D0.5761.00
678_A684_G0.5751.00
674_T678_A0.5741.00
419_A423_T0.5741.00
677_E684_G0.5741.00
223_D235_L0.5731.00
307_T647_R0.5731.00
600_T619_A0.5731.00
419_A515_A0.5721.00
658_L662_A0.5721.00
365_I650_V0.5721.00
141_R144_V0.5721.00
427_L513_A0.5711.00
608_I626_I0.5711.00
462_Y472_A0.5711.00
653_N657_A0.5701.00
617_S620_A0.5681.00
673_A676_W0.5671.00
429_E432_A0.5661.00
214_V223_D0.5661.00
676_W682_D0.5651.00
340_A345_W0.5651.00
273_Q444_E0.5651.00
473_K476_G0.5631.00
526_A529_A0.5621.00
678_A689_A0.5611.00
673_A685_V0.5611.00
621_V627_V0.5601.00
419_A492_I0.5590.99
227_V277_L0.5590.99
461_S465_I0.5590.99
400_F636_I0.5580.99
682_D690_V0.5580.99
194_A378_K0.5570.99
391_A608_I0.5570.99
235_L285_Y0.5560.99
546_G596_G0.5560.99
321_A324_I0.5560.99
383_V389_L0.5560.99
481_A504_V0.5560.99
257_P273_Q0.5550.99
462_Y469_G0.5550.99
324_I327_V0.5550.99
426_R477_T0.5540.99
439_Q444_E0.5540.99
457_D475_N0.5530.99
274_N464_E0.5520.99
413_V446_V0.5520.99
167_G171_M0.5510.99
296_L574_V0.5510.99
664_F668_G0.5510.99
194_A622_E0.5510.99
327_V330_A0.5510.99
463_E469_G0.5500.99
155_T159_F0.5490.99
231_E439_Q0.5490.99
392_L591_I0.5490.99
432_A435_E0.5490.99
617_S621_V0.5480.99
500_A554_A0.5480.99
474_V479_I0.5480.99
500_A517_I0.5480.99
648_R651_W0.5480.99
159_F164_Y0.5480.99
676_W683_V0.5470.99
132_I155_T0.5470.99
684_G687_L0.5470.99
464_E470_I0.5460.99
431_A446_V0.5450.99
666_I670_F0.5450.99
533_L541_T0.5450.99
461_S471_F0.5440.99
233_I279_I0.5440.99
241_Q276_V0.5440.99
218_D221_T0.5440.99
142_G145_F0.5440.99
527_A560_G0.5430.99
628_L635_K0.5410.99
384_K622_E0.5410.99
347_Y351_I0.5410.99
332_V335_L0.5400.99
232_S622_E0.5380.99
467_G472_A0.5370.99
250_A597_I0.5350.99
372_G642_I0.5350.99
346_V350_L0.5340.99
368_G650_V0.5340.99
336_V340_A0.5330.99
446_V504_V0.5320.99
157_G350_L0.5310.99
546_G598_N0.5310.99
620_A623_A0.5310.99
138_N149_F0.5310.99
674_T679_V0.5300.99
135_A149_F0.5300.99
376_A639_A0.5290.99
492_I515_A0.5290.99
436_L458_E0.5280.99
677_E681_S0.5280.99
133_I136_V0.5280.99
131_I175_Q0.5280.99
482_G507_A0.5270.99
469_G472_A0.5270.99
283_K289_A0.5270.99
468_H483_N0.5260.99
681_S686_T0.5260.99
435_E481_A0.5260.99
544_L592_F0.5250.99
430_A506_V0.5230.99
235_L268_S0.5230.99
667_L672_I0.5230.99
136_V139_I0.5220.99
427_L516_I0.5220.99
412_E449_A0.5220.99
396_K590_L0.5210.99
613_G631_D0.5210.99
374_G377_S0.5210.99
152_A159_F0.5210.99
405_T598_N0.5200.99
212_E223_D0.5200.99
392_L643_A0.5200.99
565_Y580_L0.5200.99
196_M621_V0.5190.99
674_T682_D0.5190.99
201_D215_S0.5190.99
151_M155_T0.5190.99
267_M289_A0.5180.99
245_M256_V0.5180.99
478_E509_D0.5170.99
501_G519_A0.5170.99
449_A454_L0.5160.99
219_V223_D0.5150.99
390_E394_Q0.5150.99
681_S685_V0.5140.99
664_F677_E0.5120.99
310_F314_F0.5120.99
529_A532_D0.5120.99
232_S247_D0.5110.99
232_S618_D0.5100.99
173_F177_G0.5100.99
147_E315_A0.5080.99
155_T162_Q0.5080.99
176_I180_F0.5080.99
649_I692_N0.5080.99
677_E685_V0.5080.99
433_Y474_V0.5060.99
522_I558_Q0.5050.99
134_R138_N0.5050.99
431_A449_A0.5050.99
164_Y167_G0.5040.99
321_A325_I0.5040.99
216_S235_L0.5040.99
581_E587_S0.5030.99
239_V262_E0.5020.99
332_V671_G0.5020.99
135_A141_R0.5020.99
158_A162_Q0.5010.99
428_L432_A0.5010.99
158_A350_L0.5010.99
656_F660_V0.5010.99
679_V690_V0.5000.99
193_S196_M0.5000.99
538_I591_I0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j09A 2 0.9758 100 0.136 Contact Map
4umwA 1 0.8533 100 0.139 Contact Map
4bbjA 1 0.8775 100 0.145 Contact Map
3j08A 2 0.8675 100 0.228 Contact Map
1mhsA 2 0.953 100 0.338 Contact Map
3b8cA 1 0.859 100 0.342 Contact Map
2zxeA 1 0.8746 100 0.363 Contact Map
3ixzA 1 0.8803 100 0.365 Contact Map
3ar4A 1 0.8647 100 0.377 Contact Map
3skxA 1 0.3632 100 0.748 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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