GREMLIN Database
CYSJ - Sulfite reductase [NADPH] flavoprotein alpha-component
UniProt: O32214 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 605 (536)
Sequences: 2646 (1804)
Seq/√Len: 77.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
464_V555_V5.4331.00
156_A169_G4.3971.00
542_S579_E4.3151.00
173_D183_R4.3061.00
539_L574_E4.1371.00
538_M545_L3.9421.00
538_M575_I3.8601.00
75_Q130_D3.5971.00
583_S586_E3.5281.00
245_N258_R3.3761.00
344_L347_L3.3751.00
397_A410_T3.1701.00
175_R178_E3.1591.00
548_W553_A3.1391.00
593_D597_Q3.0901.00
105_F113_V3.0481.00
547_E551_E3.0361.00
151_R182_K2.9961.00
175_R179_L2.9381.00
177_E183_R2.9151.00
505_Q509_Q2.8941.00
537_R540_E2.8651.00
557_I600_Y2.8421.00
521_D541_H2.8121.00
498_F527_D2.7391.00
577_E584_R2.7091.00
170_K189_D2.7001.00
68_V90_L2.6781.00
289_E315_K2.6411.00
415_R422_E2.6161.00
292_L299_P2.6141.00
290_L370_R2.4361.00
117_L205_V2.4341.00
247_N256_E2.3821.00
155_L190_C2.3771.00
240_A443_V2.3601.00
536_H539_L2.3521.00
152_F177_E2.3271.00
508_W520_M2.3081.00
87_G99_V2.2511.00
278_G393_L2.2481.00
278_G444_Y2.2421.00
542_S578_K2.2311.00
74_S131_N2.2161.00
543_A579_E2.2081.00
502_F524_F2.1691.00
470_V508_W2.1321.00
389_M426_V2.1191.00
510_N514_D2.1151.00
498_F505_Q2.1011.00
185_S204_G2.0961.00
316_E320_S2.0931.00
546_F576_I2.0891.00
359_Y371_D2.0841.00
155_L198_A2.0801.00
344_L348_L2.0771.00
547_E550_Q2.0511.00
453_L461_I2.0501.00
264_L407_V2.0451.00
167_Q171_E2.0411.00
488_K551_E2.0271.00
332_L368_L2.0141.00
477_M508_W2.0111.00
457_P483_T1.9981.00
282_E320_S1.9881.00
528_T532_V1.9641.00
338_L378_S1.9581.00
300_E315_K1.9391.00
262_L441_L1.9371.00
261_E408_H1.9191.00
90_L206_L1.9171.00
285_P319_I1.8751.00
549_L555_V1.8621.00
315_K319_I1.8621.00
73_G132_A1.8601.00
80_Q84_E1.8421.00
71_L102_M1.8191.00
102_M135_F1.8151.00
152_F173_D1.8091.00
539_L542_S1.8011.00
478_Q507_E1.7731.00
436_Q439_D1.7641.00
479_E483_T1.7611.00
526_R533_Y1.7551.00
291_L324_I1.7381.00
492_F521_D1.7051.00
480_R487_G1.6891.00
152_F181_G1.6871.00
463_M473_F1.6861.00
289_E293_K1.6841.00
410_T504_Y1.6731.00
546_F580_G1.6691.00
492_F541_H1.6681.00
174_Q178_E1.6521.00
555_V572_L1.6481.00
86_A202_L1.6461.00
240_A262_L1.6351.00
152_F183_R1.6211.00
403_N408_H1.6091.00
424_K429_I1.6031.00
277_L443_V1.6011.00
73_G120_V1.5911.00
539_L571_T1.5871.00
521_D544_E1.5781.00
403_N478_Q1.5760.99
363_R371_D1.5470.99
564_M568_V1.5440.99
118_I172_F1.5320.99
254_N496_Q1.5310.99
481_E514_D1.5300.99
435_L439_D1.5200.99
466_P473_F1.5080.99
121_S129_P1.5000.99
378_S381_E1.4880.99
147_L181_G1.4840.99
497_H500_T1.4810.99
565_A604_V1.4760.99
541_H544_E1.4710.99
73_G102_M1.4690.99
560_D565_A1.4680.99
259_H408_H1.4610.99
519_K541_H1.4470.99
490_W521_D1.4430.99
82_L198_A1.4310.99
352_N355_N1.4260.99
239_R440_T1.4250.99
502_F522_V1.4240.99
430_L442_P1.4200.99
356_V360_I1.4180.99
151_R212_A1.4170.99
338_L381_E1.4170.99
401_S479_E1.4150.99
576_I591_L1.4030.99
252_G500_T1.3960.99
86_A119_V1.3900.99
519_K544_E1.3870.99
241_E438_G1.3820.99
128_P168_T1.3810.99
573_L588_E1.3760.99
249_N257_T1.3630.99
74_S79_A1.3580.98
136_H171_E1.3570.98
574_E577_E1.3550.98
571_T575_I1.3510.98
532_V537_R1.3440.98
461_I489_A1.3440.98
481_E511_W1.3420.98
262_L443_V1.3350.98
344_L350_P1.3340.98
463_M489_A1.3320.98
543_A547_E1.3310.98
570_N573_L1.3310.98
474_R507_E1.3260.98
259_H504_Y1.3110.98
284_D424_K1.3110.98
173_D177_E1.3090.98
86_A117_L1.3090.98
153_S184_I1.3080.98
70_V87_G1.3080.98
322_Y383_V1.3060.98
318_L322_Y1.3010.98
271_Y398_S1.2900.98
586_E589_A1.2840.98
490_W545_L1.2730.98
153_S205_V1.2660.98
576_I582_M1.2660.98
462_I553_A1.2650.98
576_I590_Y1.2640.98
343_E346_E1.2540.97
117_L153_S1.2510.97
569_H591_L1.2480.97
413_A429_I1.2470.97
502_F509_Q1.2460.97
244_E261_E1.2450.97
154_V169_G1.2380.97
399_S479_E1.2360.97
521_D537_R1.2310.97
318_L379_A1.2280.97
491_M517_L1.2210.97
186_P204_G1.2170.97
545_L549_L1.2170.97
166_C169_G1.2160.97
242_V245_N1.2160.97
284_D434_R1.2110.97
150_L176_L1.2060.97
167_Q170_K1.2040.97
69_T116_L1.2030.97
288_V319_I1.2010.97
413_A428_S1.2000.97
298_D301_E1.1980.97
272_E447_H1.1910.97
136_H172_F1.1910.97
356_V361_E1.1890.96
569_H602_R1.1870.96
397_A504_Y1.1860.96
277_L407_V1.1830.96
120_V172_F1.1820.96
205_V209_L1.1770.96
336_A345_R1.1770.96
530_E536_H1.1730.96
166_C189_D1.1710.96
243_L406_E1.1650.96
238_F267_S1.1560.96
232_Y237_P1.1520.96
555_V594_M1.1510.96
118_I176_L1.1510.96
464_V572_L1.1480.96
355_N358_A1.1460.96
116_L150_L1.1450.96
411_I428_S1.1430.96
276_S393_L1.1400.96
509_Q513_K1.1390.95
233_S237_P1.1380.95
239_R442_P1.1280.95
153_S185_S1.1270.95
115_N151_R1.1240.95
462_I545_L1.1210.95
263_S406_E1.1160.95
466_P564_M1.1150.95
570_N584_R1.1100.95
208_G211_E1.1080.95
82_L119_V1.1030.95
120_V129_P1.0900.94
534_V568_V1.0890.94
78_N121_S1.0880.94
408_H474_R1.0800.94
544_E547_E1.0770.94
124_G127_E1.0760.94
576_I594_M1.0750.94
156_A166_C1.0750.94
473_F476_F1.0730.94
89_Q202_L1.0730.94
342_D345_R1.0700.94
492_F537_R1.0690.94
174_Q177_E1.0690.94
290_L294_E1.0670.94
359_Y363_R1.0640.94
291_L295_M1.0600.93
560_D563_H1.0580.93
294_E370_R1.0560.93
190_C198_A1.0470.93
477_M511_W1.0430.93
343_E371_D1.0380.93
71_L116_L1.0370.93
78_N194_Y1.0340.93
496_Q533_Y1.0330.92
492_F545_L1.0320.92
249_N256_E1.0170.92
71_L118_I1.0140.92
497_H527_D1.0140.92
149_D182_K1.0140.92
401_S483_T1.0130.92
459_T554_A1.0060.91
102_M131_N1.0020.91
525_S533_Y1.0000.91
291_L318_L0.9960.91
507_E511_W0.9950.91
241_E263_S0.9950.91
510_N513_K0.9910.91
555_V590_Y0.9890.91
339_T375_F0.9890.91
460_P551_E0.9870.91
274_G395_S0.9860.91
155_L188_V0.9850.91
584_R588_E0.9850.91
66_K115_N0.9820.90
261_E406_E0.9820.90
502_F520_M0.9700.90
576_I580_G0.9680.90
506_T509_Q0.9670.90
136_H168_T0.9660.90
176_L181_G0.9620.90
554_A601_Q0.9610.89
339_T374_P0.9590.89
135_F172_F0.9560.89
588_E592_A0.9550.89
242_V435_L0.9540.89
294_E369_V0.9510.89
417_D422_E0.9510.89
453_L476_F0.9510.89
349_A352_N0.9490.89
466_P560_D0.9490.89
291_L369_V0.9480.89
561_E565_A0.9480.89
238_F266_G0.9480.89
272_E401_S0.9470.89
103_S131_N0.9460.89
303_V314_L0.9430.89
570_N574_E0.9430.89
73_G131_N0.9400.88
577_E583_S0.9380.88
535_Q564_M0.9370.88
71_L105_F0.9350.88
573_L584_R0.9340.88
452_K475_S0.9340.88
481_E516_V0.9300.88
75_Q79_A0.9270.88
462_I555_V0.9260.88
142_R145_P0.9240.88
346_E349_A0.9230.88
287_L325_T0.9200.87
538_M571_T0.9200.87
582_M586_E0.9180.87
415_R424_K0.9160.87
496_Q526_R0.9140.87
569_H595_Q0.9140.87
69_T98_T0.9110.87
257_T503_L0.9100.87
488_K519_K0.9090.87
509_Q512_L0.9090.87
546_F590_Y0.9060.87
245_N260_V0.9050.86
343_E372_Y0.9010.86
263_S267_S0.8970.86
272_E452_K0.8970.86
70_V99_V0.8950.86
260_V431_C0.8900.86
393_L446_Q0.8900.86
248_L410_T0.8890.85
380_Q384_S0.8850.85
242_V262_L0.8830.85
264_L267_S0.8800.85
122_T169_G0.8750.85
122_T166_C0.8750.85
539_L578_K0.8740.84
466_P522_V0.8740.84
542_S575_I0.8730.84
523_A531_K0.8720.84
402_A478_Q0.8700.84
477_M516_V0.8700.84
550_Q576_I0.8680.84
569_H573_L0.8670.84
101_S104_D0.8670.84
154_V173_D0.8650.84
124_G162_Y0.8640.84
585_E588_E0.8630.84
403_N406_E0.8630.84
138_F142_R0.8600.84
273_P400_L0.8590.83
472_P558_C0.8590.83
101_S131_N0.8570.83
538_M572_L0.8570.83
277_L445_V0.8560.83
331_L365_L0.8550.83
482_E486_E0.8540.83
363_R418_A0.8530.83
259_H474_R0.8530.83
80_Q131_N0.8520.83
140_H175_R0.8500.83
250_G253_S0.8500.83
360_I363_R0.8480.83
410_T503_L0.8470.83
478_Q511_W0.8470.83
82_L157_L0.8470.83
536_H567_D0.8450.82
496_Q525_S0.8410.82
533_Y564_M0.8400.82
342_D349_A0.8400.82
261_E504_Y0.8390.82
120_V168_T0.8390.82
286_E289_E0.8370.82
396_I407_V0.8360.82
285_P434_R0.8340.82
120_V132_A0.8340.82
567_D571_T0.8330.82
295_M377_V0.8310.81
247_N255_K0.8290.81
589_A593_D0.8280.81
170_K174_Q0.8270.81
289_E319_I0.8270.81
207_K211_E0.8260.81
169_G189_D0.8260.81
347_L350_P0.8200.81
397_A409_L0.8170.80
512_L519_K0.8170.80
109_Q112_K0.8150.80
546_F579_E0.8150.80
84_E99_V0.8120.80
243_L263_S0.8120.80
569_H600_Y0.8110.80
573_L587_A0.8090.80
115_N209_L0.8080.80
542_S580_G0.8070.79
567_D570_N0.8060.79
582_M590_Y0.8040.79
535_Q568_V0.8030.79
328_T364_D0.8010.79
100_S104_D0.8000.79
113_V116_L0.7990.79
154_V183_R0.7940.78
281_P426_V0.7910.78
331_L385_I0.7890.78
456_D459_T0.7880.78
246_L259_H0.7870.78
393_L444_Y0.7840.77
460_P488_K0.7830.77
470_V491_M0.7820.77
488_K544_E0.7810.77
480_R489_A0.7800.77
324_I426_V0.7790.77
132_A558_C0.7780.77
250_G500_T0.7760.77
299_P315_K0.7760.77
203_E207_K0.7740.77
560_D603_D0.7730.76
557_I602_R0.7720.76
282_E430_L0.7700.76
549_L553_A0.7700.76
241_E440_T0.7680.76
242_V260_V0.7660.76
296_N376_S0.7660.76
249_N252_G0.7630.76
95_F213_G0.7630.76
580_G590_Y0.7610.75
242_V437_P0.7590.75
556_Y601_Q0.7590.75
477_M489_A0.7580.75
317_A322_Y0.7560.75
297_W314_L0.7530.75
162_Y166_C0.7520.74
550_Q582_M0.7520.74
103_S134_S0.7520.74
354_E358_A0.7510.74
571_T574_E0.7500.74
249_N255_K0.7490.74
89_Q206_L0.7480.74
295_M379_A0.7480.74
574_E578_K0.7480.74
264_L268_G0.7460.74
246_L506_T0.7440.74
184_I204_G0.7430.74
153_S156_A0.7420.73
477_M481_E0.7410.73
79_A119_V0.7410.73
485_A514_D0.7390.73
124_G157_L0.7370.73
534_V564_M0.7350.73
522_V537_R0.7340.73
157_L162_Y0.7320.72
105_F138_F0.7320.72
73_G90_L0.7310.72
410_T476_F0.7310.72
104_D131_N0.7290.72
273_P475_S0.7290.72
545_L553_A0.7280.72
343_E348_L0.7260.72
342_D347_L0.7260.72
345_R348_L0.7230.72
490_W544_E0.7220.71
139_L175_R0.7200.71
87_G97_V0.7200.71
120_V131_N0.7180.71
88_K92_Q0.7160.71
238_F265_E0.7160.71
125_E163_E0.7150.71
583_S587_A0.7120.70
492_F538_M0.7120.70
573_L591_L0.7110.70
303_V317_A0.7090.70
399_S408_H0.7090.70
276_S565_A0.7070.70
269_L445_V0.7070.70
68_V117_L0.7070.70
255_K412_G0.7070.70
524_F527_D0.7060.70
265_E405_D0.7050.70
595_Q602_R0.7040.70
292_L297_W0.7040.70
489_A516_V0.7020.69
490_W548_W0.6950.69
128_P132_A0.6950.69
279_V443_V0.6940.68
545_L575_I0.6930.68
234_R237_P0.6890.68
305_L322_Y0.6890.68
331_L368_L0.6880.68
536_H563_H0.6860.68
286_E424_K0.6850.67
565_A603_D0.6850.67
292_L318_L0.6850.67
474_R478_Q0.6830.67
85_N195_D0.6830.67
162_Y169_G0.6830.67
139_L176_L0.6810.67
417_D420_G0.6790.67
197_P200_E0.6790.67
590_Y594_M0.6760.66
466_P567_D0.6750.66
200_E204_G0.6740.66
183_R186_P0.6720.66
190_C197_P0.6720.66
344_L359_Y0.6710.66
123_H132_A0.6710.66
344_L351_G0.6690.66
323_E328_T0.6680.65
155_L387_R0.6680.65
323_E372_Y0.6670.65
257_T412_G0.6660.65
123_H390_P0.6650.65
72_Y79_A0.6640.65
181_G184_I0.6630.65
523_A532_V0.6630.65
81_G85_N0.6630.65
72_Y131_N0.6610.65
511_W516_V0.6590.64
164_F167_Q0.6590.64
416_Y423_R0.6580.64
520_M524_F0.6580.64
250_G505_Q0.6580.64
410_T474_R0.6580.64
463_M491_M0.6570.64
244_E437_P0.6560.64
73_G128_P0.6560.64
173_D187_R0.6560.64
385_I427_C0.6530.64
402_A405_D0.6520.64
244_E259_H0.6520.64
131_N335_A0.6490.63
462_I473_F0.6440.63
70_V90_L0.6430.63
502_F508_W0.6430.63
181_G507_E0.6420.62
89_Q93_S0.6420.62
464_V568_V0.6420.62
69_T114_T0.6370.62
164_F169_G0.6360.62
569_H588_E0.6350.62
188_V197_P0.6340.61
528_T531_K0.6330.61
499_V527_D0.6320.61
545_L572_L0.6310.61
573_L576_I0.6300.61
93_S210_N0.6290.61
356_V359_Y0.6290.61
550_Q590_Y0.6280.61
67_E96_Q0.6280.61
563_H567_D0.6270.61
136_H175_R0.6260.60
299_P302_I0.6250.60
352_N356_V0.6240.60
292_L314_L0.6240.60
184_I208_G0.6230.60
322_Y380_Q0.6220.60
397_A408_H0.6220.60
300_E574_E0.6220.60
314_L379_A0.6210.60
159_D276_S0.6210.60
122_T168_T0.6200.60
67_E95_F0.6200.60
400_L404_P0.6200.60
90_L97_V0.6200.60
105_F115_N0.6190.60
82_L192_L0.6190.60
409_L445_V0.6180.60
481_E510_N0.6170.59
572_L600_Y0.6170.59
258_R409_L0.6160.59
157_L192_L0.6150.59
165_F273_P0.6130.59
399_S404_P0.6130.59
322_Y386_L0.6120.59
411_I431_C0.6120.59
404_P437_P0.6120.59
164_F323_E0.6120.59
305_L308_Q0.6110.59
97_V100_S0.6110.59
60_P209_L0.6100.59
348_L352_N0.6100.59
333_E337_Q0.6080.58
262_L277_L0.6080.58
215_G224_A0.6070.58
237_P444_Y0.6070.58
242_V439_D0.6070.58
394_Y558_C0.6050.58
441_L584_R0.6040.58
281_P363_R0.6030.58
334_Q381_E0.6030.58
160_S191_D0.6030.58
395_S603_D0.6020.58
291_L386_L0.6020.58
70_V83_A0.6010.57
494_G525_S0.6000.57
204_G211_E0.6000.57
290_L366_L0.6000.57
185_S208_G0.6000.57
590_Y599_R0.5980.57
159_D605_Y0.5970.57
526_R531_K0.5960.57
512_L517_L0.5960.57
277_L409_L0.5960.57
537_R545_L0.5960.57
185_S205_V0.5950.57
594_M599_R0.5950.57
254_N497_H0.5940.57
585_E589_A0.5940.57
93_S206_L0.5940.57
502_F505_Q0.5930.56
419_H423_R0.5930.56
247_N257_T0.5920.56
531_K537_R0.5910.56
188_V201_W0.5900.56
125_E164_F0.5900.56
276_S558_C0.5900.56
259_H410_T0.5890.56
256_E415_R0.5890.56
85_N89_Q0.5890.56
407_V445_V0.5880.56
128_P183_R0.5870.56
600_Y603_D0.5870.56
120_V123_H0.5870.56
72_Y546_F0.5870.56
466_P470_V0.5870.56
249_N413_A0.5860.56
380_Q383_V0.5860.56
59_A92_Q0.5860.56
470_V503_L0.5850.55
283_N288_V0.5840.55
258_R432_A0.5840.55
278_G446_Q0.5830.55
592_A596_Q0.5830.55
128_P135_F0.5830.55
538_M555_V0.5830.55
413_A432_A0.5820.55
464_V553_A0.5820.55
170_K187_R0.5820.55
249_N253_S0.5800.55
334_Q377_V0.5800.55
464_V564_M0.5770.54
488_K547_E0.5760.54
491_M520_M0.5760.54
143_R146_K0.5750.54
188_V206_L0.5750.54
475_S478_Q0.5740.54
292_L295_M0.5740.54
582_M587_A0.5740.54
285_P571_T0.5730.54
282_E319_I0.5720.54
147_L502_F0.5720.54
499_V505_Q0.5720.54
557_I568_V0.5720.54
364_D421_R0.5720.54
165_F187_R0.5710.54
73_G168_T0.5710.54
352_N403_N0.5700.53
458_E488_K0.5700.53
187_R285_P0.5680.53
187_R504_Y0.5680.53
464_V538_M0.5680.53
74_S272_E0.5670.53
68_V95_F0.5650.53
225_S229_E0.5640.53
95_F206_L0.5640.53
430_L441_L0.5630.53
326_V366_L0.5620.52
276_S603_D0.5620.52
482_E485_A0.5610.52
95_F357_K0.5610.52
402_A406_E0.5610.52
560_D568_V0.5600.52
110_L590_Y0.5600.52
531_K540_E0.5600.52
462_I472_P0.5590.52
347_L352_N0.5590.52
530_E540_E0.5580.52
182_K212_A0.5580.52
511_W514_D0.5580.52
240_A267_S0.5580.52
169_G187_R0.5580.52
542_S557_I0.5570.52
84_E87_G0.5570.52
101_S123_H0.5540.51
476_F504_Y0.5540.51
454_P476_F0.5530.51
250_G538_M0.5530.51
273_P448_N0.5530.51
86_A227_T0.5530.51
237_P240_A0.5510.51
232_Y238_F0.5500.51
271_Y397_A0.5500.51
465_G473_F0.5500.51
198_A202_L0.5500.51
168_T171_E0.5490.51
208_G404_P0.5490.51
72_Y539_L0.5480.51
566_H569_H0.5480.51
293_K296_N0.5470.51
139_L277_L0.5470.51
273_P414_V0.5470.51
190_C194_Y0.5460.50
242_V409_L0.5460.50
600_Y604_V0.5450.50
116_L176_L0.5440.50
72_Y118_I0.5440.50
339_T345_R0.5440.50
438_G539_L0.5440.50
243_L513_K0.5440.50
546_F575_I0.5440.50
367_D423_R0.5440.50
69_T102_M0.5430.50
271_Y507_E0.5430.50
82_L448_N0.5430.50
185_S188_V0.5430.50
232_Y236_N0.5430.50
358_A418_A0.5420.50
69_T113_V0.5410.50
327_L368_L0.5390.50
263_S405_D0.5380.49
106_K109_Q0.5380.49
64_V181_G0.5350.49
79_A131_N0.5340.49
156_A190_C0.5340.49
548_W551_E0.5340.49
291_L382_F0.5340.49
159_D423_R0.5330.49
245_N437_P0.5320.49
258_R413_A0.5320.49
402_A482_E0.5320.49
451_F603_D0.5310.48
279_V400_L0.5310.48
112_K149_D0.5290.48
204_G584_R0.5290.48
135_F492_F0.5290.48
393_L409_L0.5290.48
151_R184_I0.5270.48
461_I556_Y0.5270.48
490_W517_L0.5260.48
98_T109_Q0.5260.48
233_S236_N0.5250.48
335_A385_I0.5250.48
140_H171_E0.5250.48
208_G212_A0.5250.48
275_D283_N0.5240.48
211_E422_E0.5240.48
288_V578_K0.5240.48
484_G516_V0.5230.47
560_D569_H0.5230.47
90_L94_G0.5230.47
282_E442_P0.5230.47
464_V545_L0.5230.47
89_Q203_E0.5220.47
454_P487_G0.5220.47
498_F509_Q0.5220.47
125_E133_L0.5210.47
327_L426_V0.5200.47
165_F341_N0.5190.47
192_L328_T0.5190.47
344_L349_A0.5190.47
570_N581_N0.5180.47
163_E353_E0.5180.47
288_V555_V0.5170.47
453_L504_Y0.5170.47
276_S395_S0.5160.47
509_Q520_M0.5160.47
69_T100_S0.5160.47
334_Q338_L0.5160.47
294_E366_L0.5160.47
369_V382_F0.5150.46
295_M382_F0.5150.46
123_H131_N0.5150.46
102_M118_I0.5150.46
368_L372_Y0.5140.46
249_N276_S0.5140.46
79_A157_L0.5140.46
465_G468_T0.5130.46
149_D207_K0.5130.46
346_E352_N0.5130.46
410_T470_V0.5130.46
103_S107_P0.5120.46
343_E355_N0.5120.46
464_V557_I0.5120.46
548_W605_Y0.5120.46
117_L184_I0.5120.46
542_S571_T0.5110.46
83_A180_G0.5110.46
325_T364_D0.5110.46
156_A213_G0.5110.46
381_E384_S0.5100.46
255_K276_S0.5100.46
459_T480_R0.5100.46
81_G88_K0.5090.46
79_A190_C0.5090.46
415_R432_A0.5080.46
466_P492_F0.5080.46
523_A533_Y0.5080.46
95_F210_N0.5070.45
87_G380_Q0.5070.45
359_Y362_G0.5070.45
278_G391_A0.5070.45
495_D605_Y0.5050.45
517_L520_M0.5040.45
126_G129_P0.5040.45
165_F226_Q0.5030.45
409_L431_C0.5030.45
412_G466_P0.5030.45
248_L504_Y0.5020.45
132_A507_E0.5020.45
281_P427_C0.5020.45
237_P442_P0.5010.45
461_I554_A0.5010.45
274_G603_D0.5010.45
284_D288_V0.5010.45
560_D564_M0.5000.45
292_L296_N0.5000.45
59_A63_A0.5000.45
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3qe2A 1 0.9008 100 0.297 Contact Map
2bpoA 1 0.9025 100 0.299 Contact Map
1tllA 2 0.881 100 0.302 Contact Map
1ddgA 1 0.6182 100 0.49 Contact Map
1f20A 1 0.6512 100 0.492 Contact Map
3qfsA 1 0.6678 100 0.498 Contact Map
2qtlA 1 0.6529 100 0.501 Contact Map
4dqlA 2 0.6017 100 0.536 Contact Map
2bmwA 1 0.4529 100 0.745 Contact Map
2b5oA 1 0.4529 100 0.75 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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