CYSI - BACSU - GREMLIN Contacts

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CYSI - Sulfite reductase [NADPH] hemoprotein beta-component

UniProt:	O32213	Sequences: MVTKILKAPDGSPSDVERIKKESDYLRGTLKEVMLDRISAGIPDDDNRLMKHHGSYLQDDRDLRNERQKQKLEPAYQFMLRVRMPGGVSTPEQWLVMDDLSQKYGNGTLKLTTRETFQMHGILKWNMKKTIQTIHSALLDTIAACGDVNRNVMCASNPYQSEIHSEVYEWSKKLSDDLLPRTRAYHEIWLDEERVAGTPEEEVEPMYGPLYLPRKFKIGIAVPPSNDIDVFSQDLGFIAIVEDGKLIGFNVAIGGGMGMTHGDTATYPQLAKVIGFCRPEQMYDVAEKTITIQRDYGNRSVRKNARFKYTVDRLGLENVKEELENRLGWSLEEAKPYHFDHNGDRYGWVEGIEDKWHFTLFVEGGRITDYDDYKLMTGLREIAKVHTGEFRLTANQNLMIANVSSDKKEEISALIEQYGLTDGKHYSALRRSSMACVALPTCGLAMAEAERYLPTLLDKIEEIIDENGLRDQEITIRMTGCPNGCARHALGEIGFIGKAPGKYNMYLGAAFDGSRLSKMYRENIGEADILSELRILLSRYAKEREEGEHFGDFVIRAGIIKATTDGTNFHD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	571 (480)
Sequences:	2528 (1337)
Seq/√Len:	61.0

ECOLI - CYSI
BACSU - CYSI
SULSO - Q97UT4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
102_Q	377_T	4.707	1.00
318_N	321_E	4.410	1.00
322_E	325_N	4.213	1.00
99_D	103_K	4.130	1.00
248_G	276_F	3.770	1.00
281_Q	329_W	3.519	1.00
95_L	384_K	3.424	1.00
548_E	556_R	3.370	1.00
321_E	325_N	3.356	1.00
498_K	501_G	3.351	1.00
314_L	318_N	3.199	1.00
404_S	407_K	3.044	1.00
298_N	304_N	2.991	1.00
278_R	281_Q	2.929	1.00
103_K	133_T	2.897	1.00
235_L	289_T	2.861	1.00
499_A	502_K	2.860	1.00
479_T	486_A	2.825	1.00
237_F	286_A	2.800	1.00
379_L	398_L	2.731	1.00
237_F	251_V	2.710	1.00
123_L	126_N	2.674	1.00
269_Q	272_K	2.661	1.00
389_E	402_N	2.649	1.00
498_K	502_K	2.579	1.00
96_V	133_T	2.488	1.00
317_E	320_K	2.485	1.00
403_V	411_I	2.480	1.00
363_E	369_D	2.479	1.00
111_L	398_L	2.474	1.00
216_F	290_I	2.456	1.00
111_L	392_L	2.410	1.00
242_E	245_K	2.343	1.00
366_R	369_D	2.334	1.00
95_L	381_E	2.291	1.00
525_G	528_D	2.277	1.00
539_R	543_E	2.238	1.00
350_E	405_S	2.229	1.00
242_E	246_L	2.219	1.00
104_Y	129_K	2.190	1.00
82_V	119_M	2.181	1.00
318_N	322_E	2.178	1.00
356_W	405_S	2.176	1.00
382_I	414_L	2.166	1.00
157_N	227_D	2.156	1.00
549_H	552_D	2.155	1.00
220_I	237_F	2.151	1.00
319_V	323_L	2.147	1.00
390_F	398_L	2.143	1.00
288_K	323_L	2.092	1.00
524_I	532_E	2.064	1.00
235_L	286_A	2.064	1.00
505_M	524_I	2.045	1.00
407_K	410_E	2.037	1.00
385_V	414_L	2.025	1.00
515_R	555_I	2.013	1.00
99_D	377_T	2.011	1.00
252_A	273_V	2.001	1.00
104_Y	133_T	1.948	1.00
363_E	368_T	1.947	1.00
187_E	190_L	1.937	1.00
164_H	350_E	1.926	1.00
219_G	228_I	1.920	1.00
183_R	187_E	1.917	1.00
292_I	323_L	1.868	1.00
433_S	453_L	1.864	1.00
409_E	413_A	1.833	1.00
232_S	490_L	1.815	1.00
269_Q	312_D	1.783	0.99
304_N	313_R	1.773	0.99
360_L	415_I	1.760	0.99
363_E	366_R	1.745	0.99
129_K	133_T	1.737	0.99
374_K	377_T	1.736	0.99
96_V	136_S	1.735	0.99
97_M	119_M	1.733	0.99
358_F	411_I	1.729	0.99
349_V	357_H	1.719	0.99
109_L	376_M	1.712	0.99
459_K	531_S	1.705	0.99
107_G	374_K	1.701	0.99
296_Y	322_E	1.688	0.99
250_N	273_V	1.687	0.99
181_R	249_F	1.671	0.99
96_V	99_D	1.641	0.99
237_F	249_F	1.638	0.99
281_Q	284_D	1.632	0.99
284_D	327_L	1.631	0.99
393_T	399_M	1.624	0.99
534_R	538_S	1.606	0.99
314_L	322_E	1.592	0.99
157_N	223_P	1.592	0.99
132_Q	136_S	1.580	0.99
378_G	418_Y	1.574	0.99
219_G	233_Q	1.571	0.99
452_Y	526_E	1.565	0.99
307_F	319_V	1.563	0.99
96_V	137_A	1.562	0.99
152_V	182_T	1.554	0.99
322_E	326_R	1.548	0.99
186_H	190_L	1.547	0.99
430_R	461_E	1.545	0.99
251_V	285_V	1.538	0.98
187_E	191_D	1.521	0.98
99_D	133_T	1.511	0.98
466_E	534_R	1.509	0.98
65_N	71_K	1.503	0.98
70_Q	73_E	1.500	0.98
298_N	313_R	1.493	0.98
382_I	411_I	1.493	0.98
188_I	191_D	1.491	0.98
67_R	71_K	1.487	0.98
91_P	384_K	1.463	0.98
94_W	376_M	1.458	0.98
381_E	384_K	1.458	0.98
153_M	394_A	1.452	0.98
253_I	319_V	1.447	0.98
100_L	130_T	1.424	0.97
274_I	323_L	1.406	0.97
102_Q	376_M	1.393	0.97
231_F	252_A	1.384	0.97
66_E	71_K	1.381	0.97
240_I	276_F	1.379	0.97
474_I	537_L	1.378	0.97
355_K	404_S	1.367	0.97
66_E	70_Q	1.360	0.97
350_E	354_D	1.359	0.97
409_E	412_S	1.347	0.96
168_Y	279_P	1.345	0.96
223_P	227_D	1.326	0.96
491_G	509_A	1.325	0.96
386_H	414_L	1.323	0.96
111_L	362_V	1.322	0.96
385_V	407_K	1.312	0.96
324_E	330_S	1.311	0.96
543_E	557_A	1.307	0.96
185_Y	220_I	1.301	0.96
463_I	534_R	1.297	0.96
544_R	556_R	1.293	0.96
237_F	282_M	1.290	0.95
94_W	390_F	1.289	0.95
100_L	133_T	1.279	0.95
249_F	282_M	1.275	0.95
184_A	187_E	1.262	0.95
410_E	414_L	1.261	0.95
324_E	328_G	1.251	0.95
246_L	249_F	1.249	0.95
510_A	514_S	1.248	0.95
364_G	369_D	1.245	0.94
91_P	383_A	1.238	0.94
230_V	238_I	1.237	0.94
84_M	89_S	1.236	0.94
181_R	279_P	1.235	0.94
274_I	316_L	1.233	0.94
510_A	555_I	1.229	0.94
162_E	402_N	1.224	0.94
66_E	73_E	1.212	0.94
350_E	356_W	1.212	0.94
56_Y	59_D	1.210	0.94
382_I	386_H	1.207	0.94
281_Q	327_L	1.206	0.93
288_K	292_I	1.204	0.93
311_V	314_L	1.201	0.93
314_L	319_V	1.196	0.93
427_S	461_E	1.192	0.93
387_T	402_N	1.181	0.93
82_V	139_L	1.176	0.93
182_T	220_I	1.176	0.93
131_I	141_T	1.173	0.93
185_Y	286_A	1.173	0.93
168_Y	247_I	1.167	0.92
47_N	50_M	1.166	0.92
275_G	324_E	1.165	0.92
459_K	534_R	1.163	0.92
355_K	405_S	1.160	0.92
295_D	326_R	1.156	0.92
109_L	119_M	1.153	0.92
537_L	540_Y	1.152	0.92
156_S	178_L	1.150	0.92
67_R	70_Q	1.149	0.92
316_L	320_K	1.147	0.92
100_L	139_L	1.147	0.92
67_R	72_L	1.145	0.92
128_K	191_D	1.141	0.91
274_I	320_K	1.139	0.91
315_G	318_N	1.127	0.91
98_D	377_T	1.126	0.91
158_P	393_T	1.121	0.91
101_S	119_M	1.117	0.91
400_I	411_I	1.114	0.90
99_D	102_Q	1.113	0.90
452_Y	478_M	1.112	0.90
287_E	291_T	1.112	0.90
381_E	385_V	1.111	0.90
276_F	279_P	1.110	0.90
414_L	418_Y	1.110	0.90
152_V	185_Y	1.109	0.90
392_L	398_L	1.109	0.90
384_K	388_G	1.107	0.90
379_L	390_F	1.107	0.90
533_L	537_L	1.106	0.90
160_Q	166_E	1.099	0.90
119_M	130_T	1.094	0.90
289_T	319_V	1.082	0.89
291_T	326_R	1.082	0.89
44_D	129_K	1.079	0.89
285_V	327_L	1.078	0.89
364_G	368_T	1.076	0.89
506_Y	519_M	1.075	0.89
272_K	316_L	1.073	0.89
272_K	312_D	1.070	0.89
102_Q	107_G	1.067	0.88
506_Y	517_S	1.065	0.88
241_V	244_G	1.063	0.88
558_G	561_K	1.061	0.88
528_D	531_S	1.057	0.88
455_T	458_D	1.057	0.88
186_H	189_W	1.053	0.88
253_I	323_L	1.050	0.88
252_A	271_A	1.042	0.87
90_T	93_Q	1.041	0.87
217_K	256_G	1.039	0.87
447_A	503_Y	1.037	0.87
163_I	222_V	1.036	0.87
126_N	129_K	1.036	0.87
553_F	557_A	1.035	0.87
337_Y	409_E	1.032	0.87
311_V	316_L	1.030	0.87
379_L	418_Y	1.030	0.87
92_E	354_D	1.029	0.87
242_E	247_I	1.028	0.87
219_G	230_V	1.028	0.87
71_K	127_M	1.028	0.87
484_G	488_H	1.027	0.86
348_W	358_F	1.025	0.86
507_L	536_L	1.025	0.86
444_L	483_N	1.021	0.86
129_K	132_Q	1.017	0.86
544_R	548_E	1.009	0.85
67_R	73_E	1.007	0.85
65_N	70_Q	1.004	0.85
539_R	553_F	1.004	0.85
458_D	462_E	1.001	0.85
130_T	138_L	1.000	0.85
206_M	290_I	0.999	0.85
414_L	417_Q	0.997	0.85
87_G	151_N	0.995	0.85
184_A	190_L	0.994	0.85
484_G	489_A	0.993	0.85
448_E	451_R	0.993	0.85
102_Q	369_D	0.988	0.84
278_R	332_E	0.987	0.84
353_E	402_N	0.987	0.84
48_R	52_H	0.986	0.84
50_M	78_F	0.984	0.84
379_L	400_I	0.980	0.84
145_C	308_K	0.979	0.84
146_G	256_G	0.978	0.84
527_A	534_R	0.976	0.84
510_A	515_R	0.976	0.84
184_A	188_I	0.971	0.83
91_P	400_I	0.968	0.83
183_R	186_H	0.963	0.83
122_I	130_T	0.963	0.83
238_I	250_N	0.961	0.83
408_K	412_S	0.954	0.82
296_Y	314_L	0.953	0.82
513_G	555_I	0.952	0.82
456_L	526_E	0.948	0.82
403_V	408_K	0.934	0.81
102_Q	374_K	0.931	0.81
459_K	530_L	0.931	0.81
413_A	417_Q	0.929	0.80
539_R	557_A	0.927	0.80
146_G	217_K	0.925	0.80
122_I	127_M	0.924	0.80
183_R	188_I	0.922	0.80
378_G	381_E	0.920	0.80
238_I	252_A	0.919	0.80
492_E	551_G	0.918	0.80
472_Q	540_Y	0.918	0.80
241_V	245_K	0.916	0.79
367_I	379_L	0.916	0.79
116_T	179_L	0.914	0.79
159_Y	357_H	0.913	0.79
505_M	529_I	0.912	0.79
84_M	116_T	0.911	0.79
348_W	412_S	0.908	0.79
65_N	73_E	0.906	0.79
109_L	117_F	0.901	0.78
58_Q	61_R	0.896	0.78
251_V	289_T	0.894	0.78
204_E	207_Y	0.893	0.78
348_W	408_K	0.893	0.78
82_V	97_M	0.887	0.77
147_D	302_R	0.885	0.77
507_L	520_Y	0.883	0.77
411_I	414_L	0.883	0.77
241_V	247_I	0.880	0.77
153_M	233_Q	0.879	0.77
364_G	434_M	0.878	0.76
120_H	217_K	0.875	0.76
85_P	151_N	0.874	0.76
349_V	359_T	0.873	0.76
358_F	408_K	0.868	0.76
518_K	555_I	0.867	0.76
363_E	367_I	0.859	0.75
61_R	302_R	0.857	0.75
359_T	393_T	0.853	0.74
66_E	208_G	0.853	0.74
526_E	530_L	0.852	0.74
153_M	219_G	0.849	0.74
369_D	377_T	0.848	0.74
328_G	331_L	0.848	0.74
50_M	55_S	0.844	0.74
459_K	463_I	0.843	0.73
92_E	137_A	0.843	0.73
395_N	490_L	0.842	0.73
340_D	344_D	0.842	0.73
168_Y	239_A	0.837	0.73
59_D	64_R	0.836	0.73
317_E	543_E	0.836	0.73
120_H	146_G	0.833	0.73
344_D	348_W	0.832	0.73
298_N	301_V	0.829	0.72
406_D	413_A	0.828	0.72
133_T	136_S	0.826	0.72
111_L	117_F	0.824	0.72
232_S	516_L	0.820	0.71
474_I	493_I	0.817	0.71
88_V	389_E	0.816	0.71
351_G	355_K	0.815	0.71
73_E	78_F	0.814	0.71
524_I	529_I	0.813	0.71
412_S	416_E	0.812	0.71
80_L	130_T	0.812	0.71
92_E	96_V	0.810	0.70
545_E	552_D	0.810	0.70
270_L	516_L	0.807	0.70
281_Q	332_E	0.806	0.70
441_T	449_A	0.805	0.70
106_N	121_G	0.805	0.70
158_P	359_T	0.803	0.70
87_G	93_Q	0.802	0.70
513_G	552_D	0.801	0.70
236_G	271_A	0.794	0.69
416_E	425_H	0.792	0.69
354_D	405_S	0.790	0.69
183_R	189_W	0.790	0.69
513_G	549_H	0.789	0.68
107_G	369_D	0.788	0.68
243_D	246_L	0.787	0.68
253_I	311_V	0.787	0.68
415_I	420_L	0.785	0.68
128_K	190_L	0.783	0.68
356_W	408_K	0.783	0.68
277_C	282_M	0.781	0.68
538_S	542_K	0.781	0.68
107_G	503_Y	0.779	0.67
289_T	307_F	0.777	0.67
159_Y	359_T	0.777	0.67
377_T	381_E	0.774	0.67
488_H	494_G	0.773	0.67
104_Y	493_I	0.773	0.67
369_D	374_K	0.772	0.67
375_L	420_L	0.771	0.67
98_D	380_R	0.768	0.66
301_V	304_N	0.767	0.66
387_T	407_K	0.766	0.66
92_E	384_K	0.765	0.66
253_I	274_I	0.763	0.66
185_Y	190_L	0.762	0.66
186_H	191_D	0.762	0.66
483_N	497_G	0.758	0.65
56_Y	145_C	0.758	0.65
274_I	331_L	0.756	0.65
328_G	332_E	0.755	0.65
95_L	380_R	0.755	0.65
360_L	379_L	0.754	0.65
244_G	247_I	0.753	0.65
168_Y	222_V	0.753	0.65
204_E	287_E	0.751	0.65
82_V	116_T	0.745	0.64
416_E	421_T	0.742	0.64
120_H	256_G	0.742	0.64
167_V	222_V	0.741	0.64
138_L	186_H	0.739	0.63
536_L	559_I	0.739	0.63
381_E	417_Q	0.734	0.63
386_H	400_I	0.734	0.63
311_V	319_V	0.734	0.63
143_A	148_V	0.733	0.63
549_H	553_F	0.728	0.62
145_C	444_L	0.728	0.62
45_D	48_R	0.727	0.62
278_R	329_W	0.726	0.62
245_K	278_R	0.725	0.62
249_F	279_P	0.723	0.62
467_N	534_R	0.720	0.61
507_L	554_V	0.719	0.61
162_E	358_F	0.717	0.61
98_D	376_M	0.714	0.61
46_D	78_F	0.713	0.61
226_N	230_V	0.711	0.60
346_Y	473_E	0.708	0.60
358_F	403_V	0.706	0.60
230_V	271_A	0.706	0.60
364_G	435_A	0.705	0.60
300_S	313_R	0.705	0.60
91_P	388_G	0.704	0.60
292_I	326_R	0.703	0.60
296_Y	318_N	0.701	0.59
356_W	402_N	0.701	0.59
554_V	559_I	0.700	0.59
439_L	448_E	0.700	0.59
277_C	285_V	0.699	0.59
251_V	277_C	0.699	0.59
434_M	477_R	0.694	0.59
240_I	250_N	0.694	0.59
331_L	344_D	0.692	0.58
343_G	408_K	0.691	0.58
88_V	401_A	0.691	0.58
218_I	286_A	0.689	0.58
475_T	492_E	0.689	0.58
242_E	248_G	0.688	0.58
46_D	49_L	0.687	0.58
555_I	560_I	0.687	0.58
74_P	446_M	0.686	0.58
296_Y	325_N	0.686	0.58
232_S	270_L	0.684	0.57
207_Y	287_E	0.684	0.57
495_F	505_M	0.683	0.57
44_D	48_R	0.683	0.57
351_G	357_H	0.682	0.57
460_I	463_I	0.681	0.57
452_Y	529_I	0.680	0.57
101_S	376_M	0.680	0.57
378_G	414_L	0.678	0.57
253_I	289_T	0.678	0.57
151_N	389_E	0.678	0.57
430_R	476_I	0.677	0.57
495_F	533_L	0.677	0.57
85_P	205_P	0.676	0.57
222_V	239_A	0.675	0.56
463_I	467_N	0.674	0.56
152_V	286_A	0.672	0.56
50_M	482_P	0.672	0.56
220_I	239_A	0.672	0.56
389_E	401_A	0.671	0.56
517_S	521_R	0.669	0.56
140_D	179_L	0.669	0.56
145_C	217_K	0.669	0.56
214_R	494_G	0.668	0.56
333_E	336_P	0.668	0.56
110_K	366_R	0.668	0.56
386_H	410_E	0.667	0.56
515_R	552_D	0.665	0.55
350_E	355_K	0.665	0.55
368_T	375_L	0.663	0.55
177_D	287_E	0.662	0.55
185_Y	188_I	0.662	0.55
108_T	441_T	0.662	0.55
113_T	258_G	0.661	0.55
237_F	253_I	0.660	0.55
236_G	258_G	0.659	0.55
162_E	357_H	0.658	0.55
383_A	388_G	0.657	0.54
86_G	156_S	0.657	0.54
318_N	323_L	0.656	0.54
386_H	407_K	0.656	0.54
245_K	355_K	0.656	0.54
378_G	382_I	0.655	0.54
279_P	331_L	0.653	0.54
344_D	431_R	0.653	0.54
253_I	320_K	0.651	0.54
376_M	390_F	0.650	0.54
452_Y	455_T	0.648	0.53
507_L	530_L	0.647	0.53
239_A	247_I	0.647	0.53
452_Y	503_Y	0.646	0.53
469_L	541_A	0.645	0.53
320_K	324_E	0.644	0.53
84_M	93_Q	0.643	0.53
156_S	393_T	0.642	0.53
158_P	399_M	0.637	0.52
92_E	525_G	0.637	0.52
350_E	385_V	0.636	0.52
321_E	406_D	0.635	0.52
188_I	249_F	0.634	0.52
156_S	220_I	0.634	0.52
206_M	291_T	0.633	0.52
478_M	495_F	0.633	0.52
112_T	505_M	0.632	0.52
351_G	402_N	0.631	0.51
168_Y	237_F	0.630	0.51
358_F	390_F	0.630	0.51
461_E	559_I	0.629	0.51
235_L	283_Y	0.629	0.51
324_E	331_L	0.629	0.51
549_H	560_I	0.627	0.51
339_F	416_E	0.625	0.51
378_G	420_L	0.625	0.51
539_R	544_R	0.624	0.51
89_S	117_F	0.624	0.51
362_V	397_N	0.623	0.51
448_E	484_G	0.623	0.51
161_S	177_D	0.623	0.51
79_M	214_R	0.622	0.50
96_V	103_K	0.622	0.50
352_I	355_K	0.622	0.50
82_V	101_S	0.619	0.50
218_I	237_F	0.618	0.50
134_I	141_T	0.617	0.50
454_P	458_D	0.617	0.50
166_E	352_I	0.616	0.50
515_R	518_K	0.616	0.50
117_F	376_M	0.615	0.50
99_D	104_Y	0.614	0.50
239_A	249_F	0.614	0.50
502_K	525_G	0.614	0.50
127_M	302_R	0.613	0.49
232_S	511_F	0.613	0.49
253_I	316_L	0.613	0.49
78_F	482_P	0.612	0.49
358_F	415_I	0.612	0.49
88_V	402_N	0.611	0.49
105_G	119_M	0.610	0.49
249_F	400_I	0.610	0.49
544_R	547_G	0.609	0.49
231_F	273_V	0.608	0.49
214_R	217_K	0.607	0.49
493_I	533_L	0.607	0.49
135_H	141_T	0.606	0.49
459_K	526_E	0.605	0.49
84_M	137_A	0.605	0.49
383_A	390_F	0.604	0.48
268_P	309_Y	0.604	0.48
89_S	390_F	0.603	0.48
395_N	456_L	0.602	0.48
50_M	57_L	0.601	0.48
256_G	308_K	0.599	0.48
550_F	553_F	0.597	0.48
446_M	498_K	0.596	0.48
214_R	299_R	0.594	0.47
224_P	227_D	0.594	0.47
457_L	461_E	0.593	0.47
103_K	557_A	0.592	0.47
467_N	538_S	0.592	0.47
317_E	321_E	0.592	0.47
66_E	72_L	0.591	0.47
168_Y	181_R	0.591	0.47
218_I	235_L	0.589	0.47
221_A	230_V	0.588	0.47
247_I	335_K	0.588	0.47
101_S	286_A	0.588	0.47
516_L	519_M	0.586	0.46
464_I	537_L	0.585	0.46
65_N	494_G	0.585	0.46
120_H	145_C	0.584	0.46
160_Q	177_D	0.584	0.46
50_M	449_A	0.584	0.46
382_I	400_I	0.583	0.46
103_K	129_K	0.582	0.46
165_S	225_S	0.580	0.46
430_R	458_D	0.579	0.46
232_S	257_M	0.578	0.45
204_E	208_G	0.577	0.45
479_T	488_H	0.577	0.45
419_G	422_D	0.575	0.45
466_E	469_L	0.575	0.45
103_K	126_N	0.574	0.45
464_I	467_N	0.573	0.45
159_Y	389_E	0.572	0.45
93_Q	151_N	0.571	0.45
274_I	474_I	0.571	0.45
256_G	516_L	0.570	0.45
437_V	450_E	0.570	0.45
182_T	293_Q	0.570	0.45
387_T	400_I	0.569	0.44
229_D	232_S	0.567	0.44
134_I	137_A	0.566	0.44
377_T	380_R	0.564	0.44
478_M	530_L	0.563	0.44
476_I	538_S	0.562	0.44
239_A	250_N	0.562	0.44
506_Y	516_L	0.561	0.44
92_E	136_S	0.561	0.44
152_V	189_W	0.560	0.43
183_R	190_L	0.560	0.43
334_A	543_E	0.560	0.43
44_D	336_P	0.560	0.43
557_A	560_I	0.560	0.43
246_L	280_E	0.559	0.43
105_G	527_A	0.559	0.43
352_I	386_H	0.558	0.43
182_T	218_I	0.558	0.43
451_R	454_P	0.557	0.43
104_Y	132_Q	0.557	0.43
97_M	109_L	0.557	0.43
220_I	304_N	0.557	0.43
299_R	396_Q	0.555	0.43
406_D	546_E	0.555	0.43
131_I	135_H	0.555	0.43
248_G	313_R	0.554	0.43
288_K	327_L	0.554	0.43
381_E	414_L	0.554	0.43
103_K	245_K	0.553	0.43
430_R	460_I	0.552	0.43
219_G	232_S	0.551	0.42
240_I	248_G	0.551	0.42
111_L	367_I	0.551	0.42
518_K	558_G	0.551	0.42
123_L	130_T	0.549	0.42
84_M	362_V	0.549	0.42
511_F	549_H	0.548	0.42
375_L	418_Y	0.547	0.42
164_H	357_H	0.547	0.42
307_F	310_T	0.547	0.42
405_S	408_K	0.546	0.42
340_D	343_G	0.546	0.42
251_V	315_G	0.546	0.42
475_T	491_G	0.545	0.42
474_I	492_E	0.545	0.42
331_L	334_A	0.544	0.42
237_F	240_I	0.544	0.42
374_K	378_G	0.542	0.41
341_H	345_R	0.542	0.41
345_R	359_T	0.541	0.41
103_K	462_E	0.541	0.41
456_L	476_I	0.539	0.41
238_I	273_V	0.539	0.41
235_L	251_V	0.538	0.41
122_I	141_T	0.537	0.41
121_G	191_D	0.536	0.41
230_V	533_L	0.536	0.41
433_S	478_M	0.535	0.41
79_M	217_K	0.535	0.41
65_N	72_L	0.535	0.41
55_S	89_S	0.535	0.41
231_F	337_Y	0.535	0.41
477_R	490_L	0.534	0.41
504_N	523_N	0.534	0.41
185_Y	191_D	0.534	0.41
87_G	152_V	0.534	0.41
410_E	413_A	0.534	0.41
542_K	545_E	0.534	0.41
433_S	476_I	0.533	0.40
505_M	532_E	0.533	0.40
356_W	404_S	0.533	0.40
274_I	296_Y	0.533	0.40
227_D	345_R	0.532	0.40
247_I	279_P	0.531	0.40
112_T	392_L	0.531	0.40
233_Q	449_A	0.530	0.40
56_Y	217_K	0.530	0.40
285_V	331_L	0.527	0.40
257_M	488_H	0.526	0.40
493_I	507_L	0.526	0.40
385_V	410_E	0.526	0.40
406_D	542_K	0.525	0.40
185_Y	189_W	0.525	0.40
330_S	406_D	0.525	0.40
421_T	425_H	0.525	0.40
374_K	417_Q	0.525	0.40
535_I	539_R	0.524	0.40
293_Q	310_T	0.523	0.39
182_T	211_Y	0.523	0.39
92_E	388_G	0.522	0.39
332_E	413_A	0.521	0.39
520_Y	559_I	0.521	0.39
122_I	220_I	0.521	0.39
166_E	282_M	0.521	0.39
178_L	249_F	0.521	0.39
510_A	551_G	0.521	0.39
83_R	190_L	0.520	0.39
181_R	220_I	0.519	0.39
126_N	130_T	0.519	0.39
167_V	247_I	0.519	0.39
385_V	406_D	0.519	0.39
345_R	357_H	0.518	0.39
79_M	113_T	0.518	0.39
260_T	308_K	0.518	0.39
242_E	276_F	0.518	0.39
318_N	325_N	0.516	0.39
316_L	374_K	0.514	0.38
160_Q	179_L	0.514	0.38
327_L	491_G	0.512	0.38
113_T	151_N	0.512	0.38
395_N	477_R	0.511	0.38
272_K	311_V	0.511	0.38
53_H	60_D	0.511	0.38
532_E	559_I	0.511	0.38
182_T	374_K	0.511	0.38
87_G	115_E	0.510	0.38
63_L	66_E	0.510	0.38
257_M	489_A	0.509	0.38
142_I	182_T	0.508	0.38
47_N	78_F	0.508	0.38
61_R	75_A	0.507	0.38
130_T	399_M	0.507	0.38
453_L	478_M	0.506	0.38
119_M	467_N	0.506	0.38
156_S	160_Q	0.506	0.38
281_Q	338_H	0.505	0.37
400_I	403_V	0.505	0.37
70_Q	74_P	0.504	0.37
243_D	278_R	0.504	0.37
473_E	549_H	0.504	0.37
80_L	131_I	0.503	0.37
128_K	257_M	0.503	0.37
474_I	540_Y	0.503	0.37
149_N	218_I	0.503	0.37
43_P	50_M	0.503	0.37
391_R	420_L	0.503	0.37
253_I	276_F	0.502	0.37
230_V	252_A	0.502	0.37
50_M	100_L	0.502	0.37
292_I	456_L	0.501	0.37
116_T	292_I	0.500	0.37
449_A	554_V	0.500	0.37

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4g38A	1	0.7828	100	0.248	Contact Map
1zj8A	1	0.9037	100	0.292	Contact Map
3b0gA	1	0.8687	100	0.349	Contact Map
2akjA	1	0.8669	100	0.352	Contact Map
3or1A	2	0.5499	100	0.752	Contact Map
3mm5A	1	0.5114	100	0.763	Contact Map
3or1B	2	0.5324	100	0.765	Contact Map
3mm5B	2	0.5044	100	0.785	Contact Map
3noyA	2	0.5674	98.8	0.938	Contact Map
4s39A	2	0.6147	92.2	0.97	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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