GREMLIN Database
NHAK - Sodium, potassium, lithium and rubidium/H(+) antiporter
UniProt: O32212 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 670 (511)
Sequences: 2163 (1463)
Seq/√Len: 64.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
367_T394_A7.0121.00
319_T400_C5.2991.00
315_I396_G5.2701.00
180_A184_V4.8881.00
496_A499_K4.5571.00
359_I408_V4.2391.00
101_Y112_L3.7531.00
102_T321_T3.5461.00
189_G239_V3.3791.00
77_L84_I3.3731.00
166_I374_I3.2751.00
316_L320_F3.2261.00
500_M506_I3.1261.00
327_F358_S3.0731.00
400_C404_I2.9951.00
195_V251_T2.9911.00
17_S36_L2.7291.00
78_W81_R2.6391.00
125_T365_A2.6281.00
96_V161_A2.5881.00
35_A39_L2.5511.00
426_L430_R2.4731.00
289_L365_A2.4691.00
316_L400_C2.4661.00
100_G112_L2.4611.00
203_R207_F2.4351.00
494_Q522_E2.3771.00
94_A325_L2.2981.00
440_T443_E2.2791.00
104_H112_L2.2481.00
174_F179_A2.2231.00
433_L497_L2.2061.00
460_Y463_K2.1091.00
508_E512_N2.1041.00
411_I415_K2.1001.00
434_I438_L2.0831.00
312_I316_L2.0511.00
159_L370_G2.0001.00
315_I392_F1.9941.00
468_R472_Y1.9881.00
65_L245_V1.9821.00
464_M467_L1.9811.00
433_L437_A1.9701.00
338_W341_N1.9641.00
127_V147_L1.9511.00
117_G374_I1.9511.00
430_R438_L1.9161.00
494_Q519_N1.9021.00
242_I245_V1.8971.00
201_I226_T1.8881.00
98_V325_L1.8861.00
152_L246_V1.8811.00
143_I357_I1.8811.00
355_L412_L1.8801.00
118_L394_A1.8601.00
62_A223_Q1.8541.00
115_A228_F1.8541.00
285_V365_A1.8471.00
193_C237_I1.8351.00
90_G94_A1.8311.00
457_I461_N1.8281.00
299_V388_N1.8141.00
430_R437_A1.8021.00
514_L517_R1.8001.00
435_K439_Q1.7991.00
123_S363_R1.7981.00
452_A456_V1.7981.00
429_A433_L1.7851.00
230_I248_G1.7831.00
125_T130_V1.7721.00
506_I510_T1.7581.00
83_P86_L1.7521.00
464_M468_R1.7521.00
130_V365_A1.7441.00
337_K341_N1.7220.99
188_L191_L1.7120.99
243_L247_A1.7090.99
102_T317_V1.6990.99
499_K503_R1.6840.99
103_I318_I1.6740.99
126_D150_E1.6710.99
177_A181_V1.6610.99
130_V362_V1.6550.99
249_G285_V1.6510.99
222_I226_T1.6310.99
84_I403_V1.6110.99
177_A180_A1.6090.99
127_V151_G1.6010.99
191_L247_A1.6010.99
428_T432_K1.6000.99
453_S460_Y1.5990.99
151_G190_G1.5850.99
429_A437_A1.5830.99
426_L513_V1.5740.99
313_G317_V1.5730.99
172_G175_S1.5710.99
491_K495_E1.5690.99
441_I446_N1.5660.99
101_Y105_W1.5650.99
111_P114_A1.5570.99
171_T174_F1.5570.99
444_D449_N1.5540.99
162_F373_S1.5510.99
43_F288_I1.5470.99
200_L203_R1.5430.99
56_F289_L1.5420.99
65_L92_V1.5390.99
440_T444_D1.5370.99
126_D154_N1.5310.99
231_Y241_G1.5310.99
453_S456_V1.5300.99
81_R85_L1.5290.99
422_R425_K1.5260.99
10_L14_I1.5160.99
235_E241_G1.5140.99
460_Y467_L1.5140.99
94_A329_W1.5080.99
309_M313_G1.4930.98
110_I114_A1.4870.98
458_A462_E1.4780.98
39_L404_I1.4720.98
121_I371_S1.4670.98
501_L511_A1.4650.98
311_V393_L1.4590.98
519_N525_Y1.4500.98
378_L382_T1.4480.98
62_A228_F1.4450.98
53_T243_L1.4410.98
200_L204_F1.4330.98
113_A169_A1.4260.98
455_A459_E1.4250.98
185_F239_V1.4250.98
219_H261_S1.4240.98
224_I277_I1.4200.98
67_N278_L1.4170.98
247_A251_T1.4160.98
169_A385_P1.4150.98
519_N522_E1.4100.98
87_L132_A1.4050.98
331_L355_L1.4040.98
319_T401_T1.4000.98
168_A171_T1.3980.98
190_G245_V1.3900.98
337_K340_F1.3800.97
101_Y104_H1.3750.97
29_V282_N1.3740.97
237_I307_S1.3720.97
453_S457_I1.3690.97
150_E361_G1.3660.97
460_Y468_R1.3630.97
359_I406_T1.3590.97
88_A153_M1.3500.97
445_M449_N1.3490.97
264_I267_Q1.3440.97
92_V157_S1.3370.97
113_A168_A1.3320.97
456_V460_Y1.3310.97
191_L243_L1.3210.97
199_F203_R1.3150.97
493_E497_L1.3100.97
432_K443_E1.2970.96
442_K449_N1.2930.96
184_V188_L1.2820.96
197_I233_A1.2800.96
84_I222_I1.2720.96
181_V185_F1.2720.96
24_I27_I1.2570.96
330_V354_T1.2530.95
124_P367_T1.2480.95
195_V247_A1.2470.95
181_V184_V1.2430.95
147_L165_A1.2420.95
63_P156_A1.2410.95
28_P127_V1.2370.95
433_L444_D1.2330.95
102_T105_W1.2300.95
188_L192_L1.2270.95
426_L429_A1.2260.95
495_E499_K1.2250.95
34_V289_L1.2240.95
154_N361_G1.2220.95
438_L444_D1.2080.94
465_K468_R1.2070.94
10_L284_L1.2060.94
375_P384_F1.2010.94
125_T289_L1.1970.94
371_S390_I1.1950.94
451_T454_L1.1920.94
117_G169_A1.1900.94
238_G245_V1.1890.94
350_G353_S1.1850.94
226_T248_G1.1850.94
192_L196_V1.1840.94
193_C239_V1.1720.94
365_A395_A1.1570.93
106_M317_V1.1570.93
490_V518_F1.1550.93
433_L440_T1.1450.93
450_K457_I1.1430.93
362_V405_A1.1420.93
381_G384_F1.1410.93
456_V472_Y1.1380.93
522_E526_A1.1330.92
30_P131_S1.1320.92
16_I27_I1.1250.92
73_P145_R1.1170.92
60_F278_L1.1080.91
156_A367_T1.1070.91
235_E238_G1.1060.91
117_G166_I1.1040.91
130_V133_L1.0970.91
74_R253_A1.0920.91
33_Q405_A1.0920.91
91_L329_W1.0900.91
227_P410_P1.0880.91
450_K453_S1.0850.91
440_T488_Q1.0810.90
12_T225_L1.0760.90
518_F522_E1.0720.90
464_M470_Q1.0690.90
72_T77_L1.0640.90
50_E54_E1.0630.90
126_D361_G1.0600.90
485_V493_E1.0530.89
511_A515_Q1.0430.89
437_A440_T1.0420.89
480_K483_R1.0400.89
77_L294_P1.0400.89
150_E154_N1.0400.89
363_R401_T1.0390.89
403_V407_V1.0370.89
30_P362_V1.0340.88
305_A309_M1.0270.88
99_G321_T1.0240.88
426_L433_L1.0220.88
75_A79_N1.0220.88
114_A169_A1.0190.88
90_G329_W1.0180.88
467_L472_Y1.0160.88
428_T431_R1.0150.87
377_F381_G1.0120.87
96_V119_A1.0110.87
458_A461_N1.0100.87
14_I17_S1.0070.87
110_I319_T1.0060.87
456_V461_N1.0050.87
126_D129_A1.0050.87
214_Q219_H1.0030.87
16_I21_N1.0030.87
104_H116_F1.0020.87
194_G198_S0.9980.87
374_I464_M0.9910.86
118_L393_L0.9910.86
484_K488_Q0.9890.86
28_P492_A0.9870.86
56_F119_A0.9870.86
341_N346_I0.9840.86
362_V365_A0.9840.86
310_K313_G0.9820.86
384_F387_R0.9790.85
97_I100_G0.9770.85
433_L443_E0.9750.85
442_K446_N0.9740.85
497_L511_A0.9740.85
369_A522_E0.9710.85
454_L457_I0.9700.85
14_I283_G0.9690.85
115_A485_V0.9680.85
95_T159_L0.9680.85
148_E368_L0.9670.85
148_E220_M0.9630.85
461_N465_K0.9620.84
96_V322_L0.9590.84
250_I367_T0.9570.84
155_D286_F0.9540.84
150_E326_R0.9530.84
432_K436_T0.9510.84
194_G326_R0.9500.84
62_A416_E0.9500.84
99_G318_I0.9440.83
126_D151_G0.9440.83
87_L330_V0.9410.83
83_P146_L0.9400.83
429_A436_T0.9380.83
434_I444_D0.9360.83
439_Q444_D0.9270.82
127_V130_V0.9270.82
390_I394_A0.9250.82
458_A463_K0.9200.82
430_R433_L0.9190.82
450_K456_V0.9190.82
7_V358_S0.9160.81
80_L83_P0.9100.81
175_S414_E0.9080.81
467_L473_T0.9060.81
124_P158_G0.9040.81
60_F365_A0.9020.80
342_K346_I0.8980.80
371_S404_I0.8980.80
122_L395_A0.8970.80
451_T455_A0.8960.80
498_M515_Q0.8930.80
314_Y393_L0.8930.80
246_V368_L0.8930.80
125_T238_G0.8920.80
442_K445_M0.8900.80
193_C197_I0.8900.80
434_I437_A0.8890.79
159_L360_S0.8890.79
223_Q274_W0.8860.79
128_V282_N0.8840.79
55_L87_L0.8830.79
62_A77_L0.8820.79
97_I101_Y0.8810.79
489_G492_A0.8800.79
238_G455_A0.8790.79
160_V278_L0.8780.79
65_L127_V0.8750.78
170_V379_E0.8740.78
122_L371_S0.8690.78
431_R435_K0.8690.78
80_L146_L0.8690.78
309_M312_I0.8680.78
227_P394_A0.8660.78
117_G165_A0.8640.78
4_F59_L0.8620.77
30_P410_P0.8610.77
124_P165_A0.8590.77
461_N468_R0.8560.77
359_I362_V0.8560.77
93_F97_I0.8560.77
220_M357_I0.8560.77
453_S458_A0.8560.77
76_E79_N0.8550.77
436_T441_I0.8530.77
486_R490_V0.8470.76
35_A320_F0.8470.76
465_K472_Y0.8470.76
332_F347_Y0.8450.76
193_C230_I0.8440.76
44_P47_L0.8430.76
332_F346_I0.8390.75
173_A177_A0.8380.75
60_F70_K0.8380.75
30_P292_Q0.8370.75
332_F335_N0.8360.75
28_P70_K0.8360.75
62_A363_R0.8350.75
356_L412_L0.8340.75
185_F189_G0.8330.75
466_N473_T0.8330.75
217_T245_V0.8320.75
121_I370_G0.8310.75
224_I516_E0.8300.75
20_V24_I0.8260.74
124_P127_V0.8240.74
378_L381_G0.8230.74
62_A230_I0.8220.74
455_A458_A0.8220.74
476_N479_K0.8200.74
139_M413_T0.8180.74
438_L445_M0.8180.74
133_L232_L0.8110.73
65_L156_A0.8080.73
438_L442_K0.8070.73
40_A490_V0.8060.72
338_W342_K0.8030.72
125_T395_A0.8020.72
217_T222_I0.8000.72
236_E465_K0.7990.72
201_I222_I0.7980.72
197_I230_I0.7980.72
365_A405_A0.7980.72
437_A441_I0.7970.72
47_L153_M0.7940.71
127_V370_G0.7930.71
60_F279_F0.7890.71
91_L124_P0.7890.71
150_E194_G0.7890.71
130_V134_S0.7870.71
450_K469_F0.7860.71
100_G103_I0.7860.71
147_L228_F0.7830.70
58_V232_L0.7830.70
196_V476_N0.7820.70
492_A496_A0.7820.70
16_I20_V0.7800.70
332_F403_V0.7790.70
69_G250_I0.7790.70
426_L437_A0.7740.69
506_I516_E0.7740.69
470_Q484_K0.7720.69
167_A171_T0.7710.69
33_Q406_T0.7690.69
14_I18_N0.7680.69
159_L369_A0.7670.69
162_F374_I0.7650.68
100_G253_A0.7650.68
354_T358_S0.7630.68
10_L18_N0.7620.68
80_L142_G0.7620.68
240_S363_R0.7600.68
182_S186_I0.7590.68
483_R510_T0.7580.68
152_L235_E0.7580.68
125_T362_V0.7560.68
141_K235_E0.7560.68
43_F46_G0.7540.67
129_A154_N0.7530.67
15_A458_A0.7520.67
106_M177_A0.7520.67
330_V357_I0.7520.67
69_G370_G0.7510.67
445_M448_T0.7500.67
125_T282_N0.7500.67
97_I116_F0.7450.66
122_L322_L0.7450.66
67_N253_A0.7440.66
189_G237_I0.7430.66
116_F174_F0.7430.66
105_W109_A0.7420.66
84_I149_G0.7420.66
432_K438_L0.7400.66
34_V68_D0.7390.66
485_V495_E0.7380.66
515_Q518_F0.7370.66
16_I219_H0.7370.66
401_T415_K0.7340.65
65_L132_A0.7320.65
203_R206_L0.7320.65
77_L330_V0.7290.65
66_F227_P0.7270.65
406_T413_T0.7270.65
126_D156_A0.7260.64
506_I511_A0.7260.64
443_E452_A0.7240.64
77_L353_S0.7230.64
127_V143_I0.7220.64
100_G116_F0.7220.64
69_G493_E0.7170.63
93_F157_S0.7150.63
11_L55_L0.7150.63
261_S267_Q0.7140.63
84_I235_E0.7130.63
348_K354_T0.7120.63
153_M243_L0.7120.63
466_N469_F0.7110.63
60_F80_L0.7100.63
259_L262_T0.7100.63
132_A315_I0.7080.62
72_T355_L0.7080.62
4_F220_M0.7070.62
150_E241_G0.7050.62
64_L203_R0.7030.62
163_K374_I0.6980.61
273_T276_I0.6980.61
146_L183_F0.6970.61
134_S493_E0.6970.61
467_L506_I0.6970.61
235_E246_V0.6970.61
242_I289_L0.6970.61
121_I162_F0.6970.61
124_P274_W0.6950.61
66_F204_F0.6950.61
332_F336_G0.6940.61
201_I248_G0.6940.61
56_F156_A0.6930.61
114_A390_I0.6930.61
87_L90_G0.6920.61
39_L195_V0.6910.61
128_V360_S0.6910.61
159_L363_R0.6900.60
497_L514_L0.6900.60
255_E258_R0.6880.60
154_N282_N0.6850.60
446_N449_N0.6840.60
389_L393_L0.6840.60
160_V372_F0.6820.60
319_T404_I0.6810.59
120_A375_P0.6800.59
432_K435_K0.6800.59
79_N230_I0.6780.59
42_S294_P0.6770.59
110_I118_L0.6770.59
124_P410_P0.6770.59
56_F74_R0.6760.59
472_Y475_S0.6750.59
152_L240_S0.6750.59
430_R440_T0.6740.59
114_A226_T0.6740.59
110_I117_G0.6730.59
129_A152_L0.6720.58
130_V160_V0.6720.58
74_R77_L0.6700.58
137_V413_T0.6650.58
12_T499_K0.6650.58
309_M320_F0.6640.58
234_A239_V0.6640.58
319_T323_M0.6630.57
33_Q359_I0.6630.57
386_E389_L0.6610.57
89_L187_S0.6600.57
130_V395_A0.6600.57
156_A273_T0.6590.57
122_L125_T0.6580.57
223_Q226_T0.6580.57
164_F179_A0.6550.57
162_F166_I0.6550.57
187_S243_L0.6550.57
148_E223_Q0.6550.57
289_L395_A0.6530.56
149_G152_L0.6530.56
454_L458_A0.6530.56
430_R436_T0.6520.56
233_A447_E0.6520.56
91_L325_L0.6510.56
281_L370_G0.6510.56
121_I151_G0.6500.56
123_S398_I0.6500.56
250_I371_S0.6490.56
241_G361_G0.6490.56
487_A522_E0.6490.56
465_K470_Q0.6480.56
193_C252_H0.6470.56
12_T15_A0.6470.56
71_R148_E0.6430.55
86_L335_N0.6430.55
64_L365_A0.6430.55
202_I371_S0.6410.55
215_D358_S0.6410.55
322_L397_V0.6400.55
272_S275_N0.6380.55
230_I233_A0.6380.55
117_G390_I0.6380.55
117_G162_F0.6360.54
399_L466_N0.6360.54
134_S139_M0.6350.54
60_F285_V0.6350.54
122_L394_A0.6340.54
64_L125_T0.6330.54
489_G493_E0.6330.54
359_I365_A0.6320.54
70_K134_S0.6310.54
126_D241_G0.6300.54
496_A500_M0.6300.54
460_Y464_M0.6290.54
430_R517_R0.6280.53
104_H111_P0.6280.53
116_F164_F0.6260.53
131_S148_E0.6260.53
289_L398_I0.6250.53
262_T500_M0.6240.53
229_V475_S0.6230.53
83_P137_V0.6180.52
96_V123_S0.6180.52
464_M474_S0.6170.52
306_I435_K0.6140.52
43_F188_L0.6130.52
67_N367_T0.6130.52
469_F472_Y0.6110.51
377_F495_E0.6110.51
6_V39_L0.6100.51
156_A240_S0.6090.51
427_L442_K0.6090.51
191_L195_V0.6080.51
17_S24_I0.6080.51
126_D364_G0.6070.51
363_R406_T0.6070.51
61_I399_L0.6060.51
454_L460_Y0.6040.51
445_M450_K0.6030.50
315_I400_C0.6030.50
39_L42_S0.6020.50
70_K245_V0.6010.50
156_A394_A0.6010.50
362_V406_T0.5990.50
154_N364_G0.5990.50
63_P231_Y0.5990.50
366_V369_A0.5980.50
463_K466_N0.5980.50
117_G120_A0.5980.50
282_N394_A0.5980.50
224_I273_T0.5970.50
198_S358_S0.5960.50
44_P371_S0.5960.50
118_L122_L0.5950.50
61_I406_T0.5940.49
38_I41_A0.5930.49
199_F324_L0.5920.49
451_T473_T0.5920.49
373_S377_F0.5910.49
275_N282_N0.5900.49
193_C306_I0.5880.49
184_V436_T0.5880.49
90_G147_L0.5870.49
448_T451_T0.5870.49
17_S32_I0.5850.48
78_W272_S0.5840.48
411_I507_P0.5840.48
457_I460_Y0.5840.48
79_N504_G0.5830.48
288_I356_L0.5820.48
119_A265_K0.5820.48
227_P230_I0.5820.48
156_A282_N0.5810.48
467_L470_Q0.5810.48
68_D362_V0.5800.48
85_L192_L0.5790.48
360_S365_A0.5790.48
15_A218_M0.5790.48
4_F55_L0.5760.47
324_L411_I0.5750.47
156_A365_A0.5750.47
132_A447_E0.5740.47
433_L439_Q0.5730.47
431_R448_T0.5730.47
129_A155_D0.5730.47
9_V458_A0.5720.47
382_T385_P0.5710.47
177_A442_K0.5710.47
132_A151_G0.5700.47
177_A414_E0.5700.47
229_V421_E0.5700.47
133_L396_G0.5690.47
434_I440_T0.5680.46
72_T185_F0.5680.46
501_L515_Q0.5680.46
16_I176_L0.5670.46
439_Q446_N0.5670.46
443_E449_N0.5670.46
183_F401_T0.5660.46
468_R471_Q0.5660.46
7_V10_L0.5660.46
128_V366_V0.5650.46
31_L410_P0.5640.46
464_M469_F0.5640.46
19_I200_L0.5640.46
323_M358_S0.5640.46
221_L280_I0.5630.46
256_Q366_V0.5630.46
441_I449_N0.5620.46
430_R449_N0.5620.46
195_V199_F0.5620.46
480_K484_K0.5620.46
62_A231_Y0.5620.46
28_P396_G0.5620.46
226_T259_L0.5610.46
194_G241_G0.5600.45
431_R485_V0.5600.45
428_T434_I0.5590.45
157_S282_N0.5590.45
126_D326_R0.5580.45
85_L476_N0.5580.45
395_A405_A0.5570.45
39_L336_G0.5570.45
471_Q475_S0.5550.45
377_F469_F0.5540.45
145_R322_L0.5530.45
12_T224_I0.5530.45
295_D328_L0.5530.45
36_L166_I0.5530.45
88_A96_V0.5520.45
16_I93_F0.5510.44
196_V491_K0.5510.44
57_F139_M0.5510.44
214_Q341_N0.5500.44
341_N348_K0.5500.44
26_F69_G0.5490.44
241_G326_R0.5470.44
155_D361_G0.5470.44
469_F473_T0.5470.44
157_S164_F0.5470.44
500_M505_D0.5460.44
220_M270_S0.5460.44
41_A367_T0.5440.44
163_K167_A0.5430.44
196_V451_T0.5430.44
17_S33_Q0.5430.44
450_K466_N0.5430.44
426_L434_I0.5420.43
336_G341_N0.5410.43
41_A394_A0.5410.43
66_F145_R0.5410.43
500_M510_T0.5400.43
226_T252_H0.5400.43
522_E525_Y0.5400.43
87_L357_I0.5390.43
352_R427_L0.5390.43
510_T513_V0.5380.43
120_A155_D0.5380.43
158_G406_T0.5380.43
363_R414_E0.5370.43
290_G364_G0.5370.43
9_V20_V0.5360.43
51_L56_F0.5360.43
136_R161_A0.5350.43
10_L409_L0.5330.42
60_F162_F0.5330.42
338_W346_I0.5320.42
93_F161_A0.5310.42
377_F383_P0.5310.42
230_I245_V0.5300.42
200_L472_Y0.5280.42
243_L511_A0.5280.42
412_L416_E0.5280.42
11_L15_A0.5270.42
298_S328_L0.5260.42
33_Q37_G0.5260.42
71_R394_A0.5250.41
31_L407_V0.5250.41
69_G247_A0.5250.41
205_R226_T0.5240.41
376_Y383_P0.5230.41
12_T16_I0.5230.41
443_E446_N0.5230.41
56_F145_R0.5220.41
202_I251_T0.5220.41
103_I119_A0.5220.41
189_G242_I0.5210.41
132_A262_T0.5210.41
494_Q515_Q0.5210.41
29_V245_V0.5210.41
67_N282_N0.5210.41
202_I207_F0.5200.41
494_Q498_M0.5190.41
65_L124_P0.5180.41
245_V401_T0.5180.41
103_I215_D0.5180.41
137_V371_S0.5180.41
28_P407_V0.5160.40
394_A398_I0.5160.40
32_I215_D0.5150.40
317_V320_F0.5150.40
492_A495_E0.5140.40
22_R111_P0.5140.40
65_L164_F0.5130.40
181_V200_L0.5130.40
434_I465_K0.5120.40
29_V139_M0.5120.40
37_G41_A0.5120.40
23_F406_T0.5110.40
156_A246_V0.5100.40
198_S202_I0.5100.40
183_F205_R0.5100.40
131_S332_F0.5100.40
92_V152_L0.5090.40
304_T400_C0.5090.40
52_N188_L0.5080.40
188_L414_E0.5080.40
233_A379_E0.5080.40
69_G117_G0.5050.39
430_R434_I0.5050.39
429_A435_K0.5050.39
325_L328_L0.5050.39
150_E156_A0.5040.39
478_I485_V0.5040.39
106_M298_S0.5040.39
66_F223_Q0.5040.39
66_F69_G0.5030.39
428_T457_I0.5030.39
126_D240_S0.5020.39
324_L497_L0.5010.39
282_N398_I0.5010.39
145_R220_M0.5000.39
263_M377_F0.5000.39
511_A521_L0.5000.39
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4cz8A 2 0.5821 100 0.576 Contact Map
4czbA 2 0.5836 100 0.58 Contact Map
4bwzA 2 0.5657 100 0.642 Contact Map
2mdfA 1 0.0851 99.6 0.875 Contact Map
1zcdA 1 0.5418 99.6 0.878 Contact Map
2l0eA 1 0.0463 98.6 0.923 Contact Map
2htgA 1 0.0403 98.2 0.931 Contact Map
2k3cA 1 0.0463 98.2 0.931 Contact Map
2m7xA 1 0.0448 97.7 0.939 Contact Map
2kbvA 1 0.0388 96.4 0.949 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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