ARCD - BACSU - GREMLIN Contacts

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ARCD - Putative arginine/ornithine antiporter

UniProt:	O32204	Sequences: MEQTKKWGFWLLTAFVVGNMVGSGIFSLPSSLASIASPFGATSAWLLTGAGVLMIALVFGHLSIRKPELTAGPQSYARALFSDPKKGNAAGFTMVWGYWVASWISNVAIITSLAGYLTSFFPILVDKREMFSIGGQEVTLGQLLTFAVCTILLWGTHAILVASINGASKLNFVTTLSKVLGFVFFIVAGLFVFQTSLFGHFYFPVQGENGTSIGIGGQVHNAAISTLWAFVGIESAVILSGRARSQRDVKRATITGLLIALSIYIIVTLITMGVLPHDKLVGSEKPFVDVLYAIVGNAGSVIMALLAILCLFGTMLGWILLGSEVPYQAAKAGDFPAFFAKTNKKGSPVIALIITNVMSQVFIFSVISRTISDAFTFLTTAATLAYLIPYLVSAIYSLKVVIKGETYDQLKGSRVRDGLIAILACAYSVFVIVTGTADLTTFILGIGLFFVGLIVYPFVSNKFQKEKQA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	469 (421)
Sequences:	24768 (15949)
Seq/√Len:	777.3

ECOLI - POTE PROY FRLA ADIC AROP PLAP PUUP ANSP YIFK CADB ARCD LYSP GABP MMUP CYCA PHEP YCAM GADC YGJI YJEH YBAT YJEM TNAB
BACSU - ARCD YHDG YBXG YDGF ASPP YFNA GABP YBGF YTNA YBEC ROCC HUTM YVBW AAPA STET ROCE YCGH YECA YDAO GERBB YNDE GERAB GERKB YFKT
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97X49 Q97WS3 Q97XM0 Q97U05 Q97WD4 Q7LXI7 Q97U33 Q97Z63 Q97ZB5 Q97VR4 Q97Y76 Q97VA6 Q97VA8 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
157_H	356_N	4.503	1.00
338_F	350_I	4.301	1.00
49_G	261_L	3.279	1.00
391_L	425_C	3.197	1.00
341_K	350_I	3.139	1.00
247_R	251_R	3.039	1.00
8_G	244_R	2.971	1.00
74_Q	332_A	2.857	1.00
399_K	403_K	2.831	1.00
243_A	248_D	2.794	1.00
95_V	329_A	2.753	1.00
189_G	270_I	2.666	1.00
330_A	340_A	2.584	1.00
343_N	349_V	2.581	1.00
241_G	331_K	2.535	1.00
150_T	360_Q	2.510	1.00
13_T	255_T	2.458	1.00
298_A	302_I	2.455	1.00
187_V	191_F	2.452	1.00
338_F	341_K	2.386	1.00
9_F	255_T	2.345	1.00
242_R	324_E	2.322	1.00
61_H	401_V	2.297	1.00
78_R	91_G	2.264	1.00
394_A	424_A	2.250	1.00
422_I	426_A	2.232	1.00
353_I	357_V	2.205	1.00
9_F	248_D	2.203	1.00
157_H	352_L	2.166	1.00
327_Y	331_K	2.159	1.00
9_F	13_T	2.120	1.00
81_F	399_K	2.119	1.00
279_K	293_A	2.100	1.00
289_D	292_Y	2.091	1.00
154_W	360_Q	2.075	1.00
12_L	243_A	2.072	1.00
158_A	162_A	2.051	1.00
165_N	169_K	2.022	1.00
50_A	54_M	2.006	1.00
78_R	88_N	1.997	1.00
149_C	363_I	1.995	1.00
161_V	349_V	1.993	1.00
448_L	452_G	1.976	1.00
150_T	363_I	1.972	1.00
333_G	337_A	1.963	1.00
8_G	11_L	1.959	1.00
99_W	355_T	1.952	1.00
176_L	180_L	1.941	1.00
58_V	394_A	1.941	1.00
339_F	354_I	1.934	1.00
32_L	41_A	1.922	1.00
204_P	208_E	1.914	1.00
251_R	255_T	1.909	1.00
454_I	458_F	1.886	1.00
438_D	441_T	1.836	1.00
419_L	423_L	1.833	1.00
254_I	258_L	1.815	1.00
81_F	395_I	1.809	1.00
160_L	316_L	1.775	1.00
426_A	430_F	1.749	1.00
245_S	248_D	1.746	1.00
276_P	279_K	1.742	1.00
289_D	293_A	1.737	1.00
87_G	90_A	1.728	1.00
77_A	94_M	1.710	1.00
96_W	452_G	1.703	1.00
44_A	222_A	1.702	1.00
11_L	172_F	1.701	1.00
154_W	356_N	1.689	1.00
446_I	450_F	1.688	1.00
343_N	347_S	1.688	1.00
94_M	392_V	1.683	1.00
110_I	315_M	1.664	1.00
201_F	204_P	1.659	1.00
16_V	256_G	1.648	1.00
180_L	184_F	1.637	1.00
283_S	289_D	1.628	1.00
161_V	353_I	1.617	1.00
117_L	148_V	1.611	1.00
110_I	153_L	1.607	1.00
399_K	402_I	1.592	1.00
40_G	219_V	1.590	1.00
153_L	359_S	1.586	1.00
258_L	262_S	1.576	1.00
51_G	427_Y	1.568	1.00
54_M	423_L	1.567	1.00
13_T	259_I	1.561	1.00
245_S	251_R	1.552	1.00
7_W	11_L	1.551	1.00
405_E	409_Q	1.540	1.00
404_G	407_Y	1.537	1.00
350_I	354_I	1.523	1.00
239_L	320_L	1.506	1.00
439_L	442_F	1.505	1.00
395_I	425_C	1.499	1.00
327_Y	342_T	1.496	1.00
416_R	420_I	1.494	1.00
70_T	241_G	1.478	1.00
48_T	226_T	1.477	1.00
56_A	257_L	1.475	1.00
437_A	441_T	1.467	1.00
181_G	306_L	1.461	1.00
179_V	183_V	1.456	1.00
404_G	409_Q	1.442	1.00
50_A	423_L	1.429	1.00
322_G	355_T	1.420	1.00
447_G	451_V	1.415	1.00
4_T	346_G	1.409	1.00
301_V	305_L	1.408	1.00
113_L	152_L	1.404	1.00
417_D	421_A	1.403	1.00
106_N	359_S	1.400	1.00
113_L	308_I	1.399	1.00
157_H	353_I	1.393	1.00
190_L	270_I	1.385	1.00
81_F	90_A	1.384	1.00
292_Y	300_S	1.373	1.00
326_P	351_A	1.372	1.00
323_S	352_L	1.368	1.00
153_L	356_N	1.362	1.00
395_I	399_K	1.358	1.00
77_A	392_V	1.349	1.00
56_A	253_T	1.345	1.00
337_A	341_K	1.343	1.00
292_Y	297_N	1.342	1.00
150_T	154_W	1.337	1.00
337_A	340_A	1.330	1.00
200_H	204_P	1.324	1.00
212_S	215_I	1.323	1.00
55_I	394_A	1.319	1.00
42_T	269_L	1.317	1.00
452_G	455_V	1.314	1.00
11_L	168_S	1.314	1.00
193_F	196_S	1.310	1.00
437_A	440_T	1.309	1.00
7_W	12_L	1.303	1.00
27_S	112_S	1.295	1.00
20_M	260_A	1.292	1.00
412_G	415_V	1.289	1.00
89_A	459_V	1.287	1.00
81_F	87_G	1.285	1.00
58_V	421_A	1.284	1.00
193_F	273_G	1.276	1.00
66_K	79_A	1.273	1.00
341_K	349_V	1.269	1.00
159_I	170_L	1.265	1.00
326_P	335_F	1.264	1.00
455_V	459_V	1.262	1.00
109_I	314_T	1.260	1.00
248_D	251_R	1.252	1.00
283_S	286_P	1.252	1.00
262_S	266_I	1.250	1.00
186_I	266_I	1.247	1.00
453_L	457_P	1.233	1.00
156_T	315_M	1.230	1.00
80_L	396_Y	1.228	1.00
9_F	251_R	1.211	1.00
75_S	79_A	1.210	1.00
57_L	254_I	1.205	1.00
437_A	442_F	1.202	1.00
450_F	454_I	1.196	1.00
439_L	443_I	1.195	1.00
295_V	299_G	1.190	1.00
10_W	14_A	1.186	1.00
99_W	326_P	1.173	1.00
350_I	353_I	1.169	1.00
12_L	252_A	1.169	1.00
194_Q	197_L	1.165	1.00
7_W	168_S	1.160	1.00
391_L	429_V	1.155	1.00
77_A	90_A	1.152	1.00
194_Q	198_F	1.152	1.00
33_A	41_A	1.149	1.00
442_F	445_G	1.149	1.00
441_T	444_L	1.140	1.00
161_V	347_S	1.136	1.00
184_F	188_A	1.136	1.00
189_G	274_V	1.134	1.00
342_T	346_G	1.132	1.00
244_R	248_D	1.127	1.00
402_I	418_G	1.123	1.00
398_L	422_I	1.117	1.00
59_F	73_P	1.115	1.00
447_G	450_F	1.113	1.00
185_F	189_G	1.113	1.00
200_H	203_F	1.111	1.00
416_R	419_L	1.110	1.00
92_F	96_W	1.103	1.00
63_S	76_Y	1.100	1.00
429_V	433_V	1.099	1.00
68_E	75_S	1.097	1.00
6_K	244_R	1.096	1.00
170_L	174_T	1.095	1.00
418_G	422_I	1.095	1.00
147_A	151_I	1.093	1.00
331_K	340_A	1.092	1.00
183_V	187_V	1.092	1.00
74_Q	328_Q	1.089	1.00
61_H	64_I	1.080	1.00
151_I	155_G	1.072	1.00
357_V	361_V	1.071	1.00
195_T	198_F	1.068	1.00
419_L	422_I	1.066	1.00
171_N	316_L	1.060	1.00
17_V	259_I	1.057	1.00
215_I	218_Q	1.057	1.00
448_L	455_V	1.054	1.00
455_V	458_F	1.034	1.00
15_F	239_L	1.033	1.00
405_E	408_D	1.028	1.00
16_V	236_A	1.025	1.00
64_I	411_K	1.023	1.00
430_F	434_T	1.020	1.00
441_T	445_G	1.019	1.00
440_T	444_L	1.016	1.00
157_H	161_V	1.014	1.00
161_V	343_N	1.008	1.00
117_L	308_I	1.008	1.00
440_T	443_I	1.008	1.00
442_F	446_I	1.006	1.00
397_S	421_A	1.005	1.00
231_V	386_Y	1.005	1.00
220_H	430_F	1.002	1.00
169_K	173_V	1.002	1.00
199_G	202_Y	0.997	1.00
276_P	293_A	0.992	1.00
154_W	158_A	0.989	1.00
79_A	404_G	0.987	1.00
424_A	428_S	0.985	1.00
114_A	148_V	0.980	1.00
17_V	260_A	0.979	1.00
438_D	442_F	0.976	1.00
240_S	249_V	0.970	1.00
185_F	291_L	0.970	1.00
425_C	429_V	0.967	1.00
445_G	448_L	0.967	1.00
234_E	238_I	0.966	1.00
443_I	447_G	0.963	1.00
46_L	265_I	0.961	1.00
445_G	449_F	0.956	1.00
108_A	379_T	0.953	1.00
114_A	149_C	0.946	1.00
68_E	79_A	0.943	1.00
164_I	320_L	0.943	1.00
174_T	313_G	0.941	1.00
21_V	24_G	0.941	1.00
274_V	290_V	0.939	1.00
391_L	395_I	0.932	1.00
199_G	203_F	0.931	1.00
65_R	407_Y	0.928	1.00
178_K	310_C	0.925	1.00
406_T	409_Q	0.921	1.00
245_S	250_K	0.921	1.00
441_T	448_L	0.919	1.00
444_L	447_G	0.917	1.00
6_K	165_N	0.916	1.00
443_I	446_I	0.916	1.00
186_I	190_L	0.909	1.00
108_A	228_W	0.909	1.00
285_K	289_D	0.908	1.00
210_G	213_I	0.902	1.00
451_V	455_V	0.901	1.00
211_T	215_I	0.900	1.00
114_A	145_T	0.899	1.00
398_L	418_G	0.896	1.00
71_A	74_Q	0.893	1.00
216_G	219_V	0.892	1.00
193_F	197_L	0.890	1.00
440_T	455_V	0.890	1.00
186_I	270_I	0.886	1.00
155_G	312_F	0.885	1.00
65_R	409_Q	0.881	1.00
49_G	230_F	0.880	1.00
424_A	427_Y	0.880	1.00
197_L	200_H	0.879	1.00
179_V	263_I	0.879	1.00
341_K	344_K	0.879	1.00
146_F	150_T	0.879	1.00
319_I	356_N	0.878	1.00
156_T	316_L	0.874	1.00
96_W	335_F	0.872	1.00
71_A	75_S	0.866	1.00
42_T	272_M	0.865	1.00
89_A	93_T	0.862	1.00
335_F	339_F	0.857	1.00
339_F	350_I	0.852	1.00
43_S	219_V	0.851	1.00
394_A	425_C	0.849	1.00
451_V	454_I	0.849	1.00
255_T	259_I	0.849	1.00
269_L	273_G	0.846	1.00
261_L	265_I	0.845	1.00
191_F	195_T	0.845	1.00
235_S	321_L	0.844	1.00
148_V	151_I	0.842	1.00
439_L	446_I	0.842	1.00
122_P	125_V	0.841	1.00
78_R	332_A	0.836	1.00
190_L	266_I	0.830	1.00
11_L	169_K	0.828	1.00
14_A	172_F	0.826	1.00
349_V	353_I	0.825	1.00
202_Y	208_E	0.820	1.00
46_L	50_A	0.816	1.00
296_G	299_G	0.816	1.00
221_N	225_S	0.813	1.00
418_G	421_A	0.808	1.00
417_D	420_I	0.807	1.00
447_G	454_I	0.805	1.00
105_S	382_A	0.799	1.00
356_N	360_Q	0.798	1.00
452_G	456_Y	0.796	1.00
53_L	57_L	0.795	1.00
428_S	431_V	0.793	1.00
398_L	402_I	0.791	1.00
211_T	214_G	0.789	1.00
77_A	396_Y	0.787	1.00
156_T	319_I	0.787	1.00
21_V	178_K	0.786	1.00
250_K	253_T	0.786	1.00
62_L	397_S	0.781	1.00
158_A	161_V	0.781	1.00
391_L	428_S	0.780	1.00
440_T	445_G	0.779	1.00
381_A	385_A	0.779	1.00
13_T	252_A	0.778	1.00
249_V	253_T	0.777	1.00
439_L	455_V	0.777	1.00
324_E	327_Y	0.774	1.00
411_K	415_V	0.774	1.00
407_Y	411_K	0.773	1.00
117_L	121_F	0.773	1.00
9_F	252_A	0.769	1.00
65_R	405_E	0.768	1.00
111_T	378_L	0.768	1.00
153_L	363_I	0.765	1.00
384_L	445_G	0.761	1.00
194_Q	202_Y	0.758	1.00
439_L	445_G	0.758	1.00
193_F	198_F	0.757	1.00
408_D	413_S	0.756	1.00
231_V	390_Y	0.755	1.00
53_L	254_I	0.752	1.00
54_M	420_I	0.752	1.00
10_W	172_F	0.751	1.00
169_K	172_F	0.750	1.00
113_L	312_F	0.750	1.00
448_L	451_V	0.750	1.00
21_V	26_F	0.748	1.00
437_A	455_V	0.747	1.00
438_D	455_V	0.747	1.00
38_P	272_M	0.745	1.00
87_G	460_S	0.744	1.00
403_K	406_T	0.743	1.00
54_M	58_V	0.742	1.00
90_A	392_V	0.740	1.00
197_L	201_F	0.738	1.00
42_T	46_L	0.737	1.00
442_F	455_V	0.735	1.00
209_N	213_I	0.732	1.00
62_L	76_Y	0.731	1.00
416_R	421_A	0.727	1.00
114_A	117_L	0.727	1.00
421_A	425_C	0.726	1.00
444_L	448_L	0.726	1.00
98_Y	102_S	0.725	1.00
55_I	428_S	0.724	1.00
160_L	352_L	0.722	1.00
113_L	311_L	0.719	1.00
338_F	354_I	0.718	1.00
74_Q	78_R	0.717	1.00
87_G	91_G	0.717	1.00
162_A	166_G	0.717	1.00
89_A	453_L	0.716	1.00
20_M	256_G	0.715	1.00
209_N	212_S	0.713	1.00
442_F	448_L	0.711	1.00
121_F	125_V	0.710	1.00
65_R	411_K	0.709	1.00
344_K	349_V	0.708	1.00
81_F	396_Y	0.705	1.00
403_K	407_Y	0.704	1.00
52_V	233_I	0.702	1.00
121_F	124_L	0.697	1.00
430_F	433_V	0.697	1.00
446_I	449_F	0.696	1.00
160_L	320_L	0.696	1.00
25_I	267_V	0.695	1.00
441_T	455_V	0.695	1.00
453_L	456_Y	0.694	1.00
451_V	459_V	0.693	1.00
190_L	194_Q	0.692	1.00
70_T	327_Y	0.690	1.00
398_L	421_A	0.689	1.00
414_R	417_D	0.688	1.00
267_V	271_T	0.687	1.00
255_T	258_L	0.687	1.00
80_L	399_K	0.687	1.00
443_I	448_L	0.687	1.00
326_P	354_I	0.686	1.00
357_V	360_Q	0.686	1.00
397_S	401_V	0.685	1.00
168_S	172_F	0.685	1.00
319_I	323_S	0.683	1.00
40_G	212_S	0.683	1.00
241_G	327_Y	0.682	1.00
10_W	169_K	0.680	1.00
97_G	389_P	0.680	1.00
203_F	208_E	0.676	1.00
198_F	273_G	0.676	1.00
374_A	377_F	0.674	1.00
43_S	47_L	0.674	1.00
196_S	199_G	0.673	1.00
421_A	428_S	0.673	1.00
343_N	346_G	0.671	1.00
18_G	175_T	0.669	1.00
437_A	448_L	0.666	1.00
323_S	351_A	0.666	1.00
13_T	16_V	0.665	1.00
404_G	408_D	0.664	1.00
442_F	459_V	0.664	1.00
103_W	358_M	0.662	1.00
43_S	46_L	0.659	1.00
41_A	268_T	0.659	1.00
438_D	448_L	0.659	1.00
156_T	312_F	0.658	1.00
259_I	263_I	0.658	1.00
456_Y	460_S	0.657	1.00
218_Q	221_N	0.655	1.00
385_A	389_P	0.653	1.00
154_W	157_H	0.653	1.00
402_I	405_E	0.653	1.00
118_T	122_P	0.652	1.00
415_V	419_L	0.648	1.00
266_I	270_I	0.648	1.00
391_L	432_I	0.646	1.00
396_Y	400_V	0.645	1.00
297_N	301_V	0.645	1.00
264_Y	268_T	0.645	1.00
237_V	253_T	0.645	1.00
28_L	379_T	0.644	1.00
161_V	352_L	0.644	1.00
74_Q	95_V	0.643	1.00
445_G	455_V	0.643	1.00
116_Y	307_A	0.642	1.00
345_K	349_V	0.640	1.00
57_L	420_I	0.639	1.00
22_G	26_F	0.639	1.00
457_P	460_S	0.638	1.00
101_A	386_Y	0.637	1.00
403_K	409_Q	0.636	1.00
105_S	108_A	0.634	1.00
90_A	93_T	0.634	1.00
191_F	194_Q	0.633	1.00
29_P	268_T	0.631	1.00
449_F	452_G	0.630	1.00
150_T	364_F	0.630	1.00
330_A	339_F	0.630	1.00
242_R	348_P	0.629	1.00
186_I	267_V	0.629	1.00
438_D	445_G	0.627	1.00
267_V	287_F	0.624	1.00
442_F	449_F	0.623	1.00
59_F	393_S	0.621	1.00
242_R	342_T	0.621	1.00
21_V	263_I	0.620	1.00
442_F	457_P	0.619	1.00
56_A	233_I	0.619	1.00
152_L	315_M	0.618	1.00
197_L	204_P	0.617	1.00
414_R	420_I	0.617	1.00
32_L	226_T	0.616	1.00
73_P	234_E	0.613	1.00
80_L	400_V	0.612	1.00
42_T	265_I	0.612	1.00
177_S	306_L	0.611	1.00
17_V	175_T	0.611	1.00
109_I	315_M	0.610	1.00
279_K	282_G	0.608	1.00
121_F	126_D	0.608	1.00
445_G	452_G	0.606	1.00
166_G	169_K	0.605	1.00
456_Y	459_V	0.605	1.00
376_T	379_T	0.603	1.00
107_V	362_F	0.603	1.00
117_L	152_L	0.602	1.00
231_V	234_E	0.601	1.00
447_G	452_G	0.597	1.00
447_G	458_F	0.597	1.00
450_F	453_L	0.596	1.00
47_L	223_A	0.596	1.00
247_R	250_K	0.595	1.00
103_W	355_T	0.594	1.00
164_I	239_L	0.592	1.00
195_T	199_G	0.589	1.00
168_S	316_L	0.588	1.00
438_D	444_L	0.588	1.00
19_N	317_G	0.587	1.00
73_P	238_I	0.586	1.00
285_K	288_V	0.586	1.00
298_A	301_V	0.584	1.00
146_F	363_I	0.584	1.00
48_T	227_L	0.584	1.00
6_K	164_I	0.584	1.00
63_S	237_V	0.583	1.00
278_D	282_G	0.583	1.00
212_S	219_V	0.582	1.00
452_G	459_V	0.582	1.00
48_T	230_F	0.581	1.00
54_M	424_A	0.580	1.00
63_S	249_V	0.580	1.00
6_K	10_W	0.579	1.00
422_I	425_C	0.579	1.00
454_I	457_P	0.578	1.00
437_A	446_I	0.578	1.00
19_N	318_W	0.578	1.00
119_S	122_P	0.578	1.00
305_L	309_L	0.577	1.00
166_G	170_L	0.576	1.00
348_P	351_A	0.575	1.00
354_I	358_M	0.575	1.00
157_H	319_I	0.574	1.00
60_G	64_I	0.574	1.00
339_F	351_A	0.574	1.00
188_A	295_V	0.573	1.00
74_Q	91_G	0.573	1.00
403_K	408_D	0.572	1.00
31_S	376_T	0.571	1.00
97_G	388_I	0.571	1.00
19_N	235_S	0.570	1.00
152_L	156_T	0.570	1.00
198_F	272_M	0.569	1.00
445_G	450_F	0.569	1.00
322_G	326_P	0.568	1.00
243_A	249_V	0.568	1.00
38_P	42_T	0.567	1.00
62_L	80_L	0.566	1.00
188_A	192_V	0.566	1.00
310_C	313_G	0.566	1.00
246_Q	251_R	0.564	1.00
216_G	220_H	0.562	1.00
153_L	360_Q	0.562	1.00
172_F	176_L	0.562	1.00
58_V	414_R	0.561	1.00
56_A	60_G	0.561	1.00
45_W	229_A	0.561	1.00
120_F	305_L	0.559	1.00
110_I	114_A	0.558	1.00
428_S	432_I	0.557	1.00
10_W	13_T	0.555	1.00
427_Y	431_V	0.555	1.00
163_S	166_G	0.554	1.00
107_V	378_L	0.554	1.00
188_A	296_G	0.554	1.00
119_S	304_A	0.553	1.00
270_I	273_G	0.552	1.00
231_V	382_A	0.551	1.00
454_I	459_V	0.550	1.00
72_G	237_V	0.548	1.00
162_A	345_K	0.547	1.00
80_L	87_G	0.547	1.00
61_H	412_G	0.546	1.00
220_H	434_T	0.546	1.00
94_M	389_P	0.546	1.00
324_E	342_T	0.545	1.00
319_I	352_L	0.545	1.00
171_N	313_G	0.544	1.00
212_S	216_G	0.544	1.00
55_I	234_E	0.542	1.00
259_I	266_I	0.542	1.00
432_I	442_F	0.541	1.00
38_P	277_H	0.541	1.00
61_H	415_V	0.541	1.00
438_D	443_I	0.540	1.00
246_Q	411_K	0.539	1.00
361_V	364_F	0.539	1.00
449_F	453_L	0.539	1.00
16_V	20_M	0.538	1.00
238_I	321_L	0.537	1.00
89_A	457_P	0.537	1.00
433_V	436_T	0.537	1.00
417_D	422_I	0.537	1.00
291_L	295_V	0.536	1.00
426_A	429_V	0.535	1.00
36_A	222_A	0.535	1.00
17_V	20_M	0.535	1.00
102_S	318_W	0.534	1.00
123_I	126_D	0.533	1.00
438_D	447_G	0.533	1.00
446_I	452_G	0.532	1.00
398_L	425_C	0.531	1.00
442_F	447_G	0.529	1.00
405_E	411_K	0.528	1.00
177_S	181_G	0.528	1.00
109_I	112_S	0.528	1.00
200_H	208_E	0.526	1.00
437_A	445_G	0.525	1.00
146_F	149_C	0.525	1.00
444_L	450_F	0.525	1.00
58_V	424_A	0.521	1.00
445_G	459_V	0.520	1.00
155_G	159_I	0.520	1.00
259_I	262_S	0.519	1.00
12_L	239_L	0.516	1.00
234_E	390_Y	0.516	1.00
101_A	104_I	0.515	1.00
324_E	348_P	0.513	1.00
37_S	40_G	0.512	1.00
152_L	312_F	0.512	1.00
199_G	204_P	0.512	1.00
286_P	290_V	0.512	1.00
104_I	381_A	0.511	1.00
439_L	452_G	0.510	1.00
338_F	342_T	0.510	1.00
97_G	101_A	0.509	1.00
175_T	178_K	0.508	1.00
26_F	178_K	0.508	1.00
109_I	311_L	0.507	1.00
51_G	54_M	0.507	1.00
275_L	289_D	0.506	1.00
151_I	154_W	0.506	1.00
167_A	320_L	0.506	1.00
373_D	377_F	0.506	1.00
417_D	424_A	0.504	1.00
121_F	148_V	0.504	1.00
443_I	456_Y	0.504	1.00
45_W	268_T	0.504	1.00
25_I	182_F	0.503	1.00
446_I	453_L	0.502	1.00
444_L	452_G	0.502	1.00
22_G	264_Y	0.501	1.00
91_G	95_V	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.8934	100	0.291	Contact Map
3giaA	1	0.8998	100	0.364	Contact Map
4djkA	2	0.8827	100	0.365	Contact Map
3dh4A	3	0.8934	98.9	0.853	Contact Map
2xq2A	2	0.8913	98.8	0.859	Contact Map
2jlnA	1	0.8678	98.6	0.869	Contact Map
2a65A	2	0.9382	98.4	0.879	Contact Map
4wgvA	2	0.7783	97.6	0.9	Contact Map
4xp4A	1	0.9424	97.5	0.902	Contact Map
4us3A	1	0.8806	97.4	0.903	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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