YUSP - BACSU - GREMLIN Contacts

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YUSP - Uncharacterized MFS-type transporter YusP

UniProt:	O32182	Sequences: MKMSKEGKQSKRTLLITGLIIAMFFSALDGTIVGTAMPKIVGDLGGLSMMTWLTTAYLLTSTTIVPIAGKLADLLGRRIVYVSGLIIFMAASALCGMANNMTELIIFRGLQGIGGGIMMPMAMIVIGDLFTGKQRAKFQGVFGAIYGLASVIGPQIGGWIVDSLNWKWVFYINLPVGIIAVIFIARGLQGRQQTGPINFDIAGIFTMIVGVVSLLLALSFGGKDYAWDSWQILGLFALALIGIVSFIIVESKAKEPILPMYLFKNRTFTFLNLIGFFMSIGMFGAITFVPFFMQGIVGVSASESGTIMTPMMISMIITSIIGGQLVYKIGIKPQIITGMLVMAGGFLLLTTLDLDTSKLVATSFMAIIGLGMGLVMPILTLALQESFSKEELGVVTSSSQFFRSIGGTFGITMLGAVMNARSGNLLTDKLVPYLDSLPAQASSFAAQLKGMIDTNPQGLLQSLFSPDAVKQIPAAFSSHIVPILKTSLMDSLHSVFYTGLIFIAVGAVFTLFLKPIKLSNKKAEDQQEKEKAAKAVESPSH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	541 (422)
Sequences:	28288 (19845)
Seq/√Len:	966.1

ECOLI - EMRB EMRY MDTD HSRA YEBQ PROP NANT YAJR GALP UHPT XYLE YDIN RHMT ARAE YIHP SHIA YIHO UHPC MDFA YDJE YGCS YAAU MDTM MDTG YDFJ SETC YJJL MHPT YDJK GARP GLPT NEPI YEGT EXUT UIDB ENTS YJHB DGOT YIHN YHJE YQCE BCR YICJ YDHC GUDP MELB AMPG KGTP YHJX YAGG SETB MDTH YBJJ SETA YDIM YDHP ARAJ SOTB YNFM FUCP EMRD MDTL YEAN NARU
BACSU - YUSP YHCA BMR3 YFIU YUBD LMRB YCNB MMR TCRB YVKA YWOD IOLT CSBC YNCC YITG EXUT YBFB YKUC YWFA YWTG YVMA YFIG YFHI GUTA IOLF YCXA YYBO NASA ARAE GUDP YYAJ YNAJ YYBF YFIS NAIP GLPT YTBD YHJO YYCB NARK YFNC YQJV YVQJ BMR2 YQGE YDEG YDER CSBX YJBB YXAM YDGK YCEJ YFKL
HALSA - Q9HSM8 O54630 Q9HS33
SULSO - Q97VC8 Q97YH0 Q97U91 Q97Y15 Q97WR9 Q97X47 Q97VB9 Q97YY8 Q97U43 Q97VV2 Q97YL8 Q7LX71 Q7LX65 Q97WR1 Q97U99 Q97VU3 Q97U98 Q97UD8 Q97Y43 Q97UY7 Q97VB7 Q97V89 Q97U80 Q97UR4 Q97VT2 Q97WS7 Q97U76 Q97Y11

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
99_N	103_E	5.398	1.00
89_M	177_G	4.436	1.00
87_I	114_G	3.873	1.00
96_G	171_Y	3.568	1.00
210_G	243_I	3.346	1.00
206_T	249_V	3.222	1.00
102_T	106_I	3.179	1.00
94_L	107_F	3.141	1.00
387_F	395_V	2.899	1.00
348_L	364_F	2.825	1.00
261_Y	391_E	2.813	1.00
100_N	103_E	2.761	1.00
77_R	128_D	2.646	1.00
56_A	109_G	2.627	1.00
209_V	242_G	2.625	1.00
12_R	134_Q	2.603	1.00
217_A	236_F	2.576	1.00
214_L	239_A	2.560	1.00
318_T	370_L	2.486	1.00
202_A	249_V	2.413	1.00
314_S	366_A	2.394	1.00
300_S	303_E	2.374	1.00
82_V	185_A	2.349	1.00
82_V	181_V	2.213	1.00
64_I	113_I	2.182	1.00
164_L	168_W	2.131	1.00
60_T	109_G	2.111	1.00
182_I	186_R	2.100	1.00
244_V	248_I	2.090	1.00
91_A	114_G	2.078	1.00
95_C	107_F	2.066	1.00
233_L	237_A	2.031	1.00
134_Q	137_K	2.031	1.00
221_G	227_W	2.027	1.00
388_S	391_E	2.013	1.00
200_D	203_G	2.012	1.00
259_P	391_E	1.999	1.00
345_G	368_I	1.981	1.00
280_I	410_G	1.948	1.00
103_E	107_F	1.944	1.00
276_F	406_G	1.905	1.00
46_G	49_M	1.879	1.00
91_A	110_L	1.876	1.00
184_I	188_L	1.842	1.00
160_I	168_W	1.790	1.00
84_G	117_I	1.785	1.00
91_A	107_F	1.772	1.00
22_A	81_Y	1.771	1.00
210_G	239_A	1.771	1.00
93_A	97_M	1.765	1.00
284_G	414_L	1.745	1.00
165_N	168_W	1.701	1.00
20_I	145_I	1.681	1.00
253_A	256_P	1.669	1.00
68_A	117_I	1.668	1.00
213_S	235_L	1.666	1.00
49_M	101_M	1.662	1.00
324_Q	328_K	1.662	1.00
213_S	242_G	1.660	1.00
234_G	238_L	1.645	1.00
101_M	105_I	1.642	1.00
136_A	327_Y	1.637	1.00
162_D	302_S	1.635	1.00
73_D	393_G	1.627	1.00
341_V	371_G	1.625	1.00
36_A	161_V	1.621	1.00
249_V	253_A	1.620	1.00
292_F	297_V	1.617	1.00
294_Q	304_S	1.607	1.00
130_F	138_F	1.600	1.00
82_V	184_I	1.584	1.00
56_A	105_I	1.583	1.00
95_C	104_L	1.569	1.00
345_G	371_G	1.569	1.00
246_F	250_E	1.568	1.00
283_F	407_G	1.564	1.00
24_F	149_A	1.552	1.00
213_S	238_L	1.546	1.00
78_R	82_V	1.543	1.00
92_S	173_N	1.541	1.00
198_N	255_E	1.513	1.00
338_G	374_L	1.509	1.00
263_F	269_T	1.497	1.00
251_S	261_Y	1.492	1.00
98_A	103_E	1.490	1.00
210_G	242_G	1.490	1.00
299_V	307_I	1.485	1.00
201_I	205_F	1.482	1.00
131_T	134_Q	1.473	1.00
343_A	347_L	1.473	1.00
217_A	239_A	1.472	1.00
39_K	42_G	1.467	1.00
15_L	129_L	1.457	1.00
16_I	130_F	1.454	1.00
132_G	135_R	1.440	1.00
345_G	364_F	1.440	1.00
86_I	181_V	1.436	1.00
269_T	273_L	1.428	1.00
220_F	225_Y	1.424	1.00
29_D	32_I	1.419	1.00
98_A	107_F	1.418	1.00
357_S	360_V	1.414	1.00
230_W	234_G	1.409	1.00
303_E	306_T	1.399	1.00
359_L	363_S	1.398	1.00
247_I	251_S	1.397	1.00
247_I	260_M	1.388	1.00
57_Y	115_G	1.388	1.00
248_I	252_K	1.382	1.00
271_L	383_L	1.380	1.00
63_T	208_I	1.377	1.00
79_I	190_G	1.374	1.00
71_L	80_V	1.365	1.00
72_A	77_R	1.362	1.00
340_L	344_G	1.354	1.00
53_L	104_L	1.335	1.00
333_P	336_I	1.335	1.00
183_F	187_G	1.333	1.00
83_S	87_I	1.326	1.00
36_A	169_V	1.322	1.00
127_G	135_R	1.322	1.00
162_D	300_S	1.322	1.00
216_L	220_F	1.321	1.00
248_I	251_S	1.317	1.00
93_A	174_L	1.313	1.00
32_I	169_V	1.312	1.00
203_G	249_V	1.306	1.00
209_V	213_S	1.299	1.00
239_A	243_I	1.291	1.00
90_A	94_L	1.289	1.00
94_L	103_E	1.287	1.00
299_V	303_E	1.274	1.00
64_I	116_G	1.273	1.00
238_L	242_G	1.269	1.00
18_G	187_G	1.262	1.00
323_G	327_Y	1.253	1.00
358_K	362_T	1.247	1.00
78_R	185_A	1.246	1.00
206_T	242_G	1.246	1.00
41_V	50_M	1.245	1.00
159_W	163_S	1.238	1.00
72_A	121_M	1.234	1.00
27_A	146_Y	1.231	1.00
424_N	428_D	1.220	1.00
206_T	245_S	1.217	1.00
13_T	17_T	1.217	1.00
89_M	181_V	1.216	1.00
70_K	74_L	1.213	1.00
20_I	141_V	1.199	1.00
332_K	336_I	1.196	1.00
322_G	374_L	1.194	1.00
168_W	175_P	1.192	1.00
12_R	130_F	1.188	1.00
347_L	350_T	1.186	1.00
259_P	394_V	1.185	1.00
178_I	182_I	1.177	1.00
314_S	318_T	1.172	1.00
338_G	375_V	1.171	1.00
217_A	232_I	1.169	1.00
324_Q	327_Y	1.167	1.00
18_G	183_F	1.167	1.00
82_V	86_I	1.159	1.00
102_T	105_I	1.158	1.00
330_G	333_P	1.157	1.00
347_L	351_T	1.157	1.00
318_T	373_G	1.155	1.00
174_L	178_I	1.150	1.00
293_M	307_I	1.143	1.00
97_M	171_Y	1.138	1.00
303_E	307_I	1.137	1.00
337_T	374_L	1.133	1.00
363_S	366_A	1.124	1.00
85_L	180_A	1.115	1.00
311_M	369_G	1.111	1.00
421_R	425_L	1.111	1.00
29_D	173_N	1.108	1.00
325_L	329_I	1.106	1.00
359_L	362_T	1.105	1.00
245_S	248_I	1.103	1.00
236_F	240_L	1.100	1.00
67_I	204_I	1.099	1.00
21_I	180_A	1.099	1.00
217_A	235_L	1.092	1.00
240_L	244_V	1.090	1.00
293_M	361_A	1.087	1.00
89_M	93_A	1.087	1.00
25_F	177_G	1.084	1.00
243_I	247_I	1.082	1.00
18_G	180_A	1.078	1.00
160_I	164_L	1.076	1.00
193_Q	196_P	1.074	1.00
89_M	174_L	1.072	1.00
203_G	253_A	1.070	1.00
30_G	58_L	1.069	1.00
265_N	269_T	1.066	1.00
272_N	402_F	1.061	1.00
225_Y	231_Q	1.057	1.00
225_Y	232_I	1.057	1.00
351_T	364_F	1.053	1.00
205_F	209_V	1.052	1.00
71_L	75_L	1.050	1.00
425_L	428_D	1.049	1.00
81_Y	184_I	1.047	1.00
127_G	392_L	1.045	1.00
87_I	91_A	1.041	1.00
167_K	171_Y	1.041	1.00
76_G	79_I	1.040	1.00
55_T	219_S	1.040	1.00
345_G	367_I	1.039	1.00
261_Y	264_K	1.033	1.00
77_R	190_G	1.032	1.00
94_L	97_M	1.029	1.00
342_M	371_G	1.027	1.00
333_P	337_T	1.026	1.00
73_D	77_R	1.023	1.00
126_I	142_F	1.018	1.00
133_K	137_K	1.014	1.00
220_F	224_D	1.014	1.00
60_T	112_G	1.013	1.00
158_G	301_A	1.007	1.00
14_L	187_G	1.007	1.00
266_R	270_F	1.006	1.00
360_V	364_F	1.006	1.00
360_V	363_S	1.005	1.00
425_L	429_K	1.005	1.00
225_Y	229_S	1.003	1.00
99_N	102_T	0.995	1.00
353_D	356_T	0.988	1.00
181_V	185_A	0.982	1.00
421_R	424_N	0.982	1.00
69_G	73_D	0.980	1.00
383_L	399_S	0.979	1.00
249_V	252_K	0.978	1.00
52_W	56_A	0.965	1.00
136_A	323_G	0.964	1.00
156_I	159_W	0.962	1.00
265_N	391_E	0.962	1.00
122_A	142_F	0.959	1.00
275_G	399_S	0.959	1.00
228_D	233_L	0.954	1.00
265_N	388_S	0.953	1.00
338_G	371_G	0.953	1.00
352_L	356_T	0.952	1.00
56_A	60_T	0.952	1.00
60_T	64_I	0.951	1.00
79_I	83_S	0.947	1.00
54_T	287_T	0.946	1.00
268_F	272_N	0.946	1.00
278_M	375_V	0.945	1.00
83_S	86_I	0.942	1.00
272_N	398_S	0.940	1.00
348_L	351_T	0.939	1.00
321_I	324_Q	0.939	1.00
32_I	157_G	0.938	1.00
311_M	368_I	0.937	1.00
258_L	398_S	0.937	1.00
232_I	235_L	0.937	1.00
183_F	186_R	0.933	1.00
95_C	170_F	0.932	1.00
431_V	434_L	0.932	1.00
223_K	226_A	0.930	1.00
307_I	358_K	0.929	1.00
318_T	374_L	0.927	1.00
192_Q	195_G	0.923	1.00
241_I	245_S	0.918	1.00
73_D	394_V	0.917	1.00
136_A	140_G	0.912	1.00
198_N	254_K	0.912	1.00
99_N	107_F	0.911	1.00
268_F	395_V	0.910	1.00
215_L	408_T	0.907	1.00
91_A	94_L	0.906	1.00
80_V	117_I	0.903	1.00
276_F	402_F	0.903	1.00
406_G	410_G	0.903	1.00
26_S	118_M	0.902	1.00
266_R	269_T	0.902	1.00
19_L	122_A	0.902	1.00
204_I	208_I	0.899	1.00
231_Q	234_G	0.898	1.00
160_I	172_I	0.891	1.00
293_M	297_V	0.887	1.00
337_T	341_V	0.885	1.00
245_S	249_V	0.884	1.00
40_I	104_L	0.877	1.00
417_V	421_R	0.874	1.00
37_M	50_M	0.874	1.00
97_M	107_F	0.873	1.00
80_V	83_S	0.871	1.00
199_F	204_I	0.870	1.00
209_V	212_V	0.869	1.00
209_V	238_L	0.868	1.00
428_D	431_V	0.867	1.00
190_G	193_Q	0.866	1.00
163_S	302_S	0.865	1.00
288_F	415_G	0.865	1.00
106_I	110_L	0.863	1.00
53_L	101_M	0.862	1.00
229_S	232_I	0.862	1.00
33_V	53_L	0.860	1.00
238_L	245_S	0.860	1.00
39_K	43_D	0.859	1.00
34_G	54_T	0.858	1.00
318_T	322_G	0.857	1.00
334_Q	337_T	0.857	1.00
363_S	367_I	0.855	1.00
49_M	102_T	0.853	1.00
99_N	167_K	0.850	1.00
320_I	324_Q	0.850	1.00
265_N	386_S	0.850	1.00
103_E	106_I	0.849	1.00
244_V	247_I	0.849	1.00
325_L	334_Q	0.844	1.00
231_Q	235_L	0.843	1.00
356_T	360_V	0.842	1.00
430_L	434_L	0.841	1.00
362_T	366_A	0.839	1.00
318_T	321_I	0.839	1.00
218_L	221_G	0.838	1.00
63_T	212_V	0.837	1.00
227_W	232_I	0.835	1.00
326_V	378_I	0.830	1.00
322_G	373_G	0.829	1.00
28_L	32_I	0.829	1.00
186_R	189_Q	0.828	1.00
289_V	365_M	0.828	1.00
106_I	109_G	0.828	1.00
210_G	247_I	0.827	1.00
313_I	317_I	0.825	1.00
346_F	368_I	0.823	1.00
351_T	360_V	0.819	1.00
151_V	312_M	0.818	1.00
40_I	44_L	0.814	1.00
162_D	301_A	0.813	1.00
75_L	80_V	0.813	1.00
144_A	148_L	0.813	1.00
294_Q	301_A	0.813	1.00
93_A	171_Y	0.803	1.00
66_P	207_M	0.803	1.00
329_I	334_Q	0.802	1.00
237_A	241_I	0.800	1.00
208_I	212_V	0.800	1.00
79_I	82_V	0.795	1.00
310_P	314_S	0.795	1.00
23_M	146_Y	0.786	1.00
157_G	161_V	0.785	1.00
331_I	382_A	0.785	1.00
128_D	392_L	0.784	1.00
211_V	401_F	0.783	1.00
43_D	167_K	0.780	1.00
428_D	432_P	0.780	1.00
68_A	84_G	0.776	1.00
159_W	302_S	0.775	1.00
236_F	239_A	0.775	1.00
267_T	386_S	0.774	1.00
69_G	397_S	0.770	1.00
293_M	299_V	0.770	1.00
251_S	260_M	0.768	1.00
346_F	350_T	0.768	1.00
40_I	50_M	0.764	1.00
306_T	310_P	0.764	1.00
13_T	130_F	0.764	1.00
268_F	383_L	0.763	1.00
126_I	138_F	0.760	1.00
344_G	348_L	0.759	1.00
211_V	405_I	0.759	1.00
85_L	181_V	0.757	1.00
349_L	352_L	0.757	1.00
336_I	340_L	0.757	1.00
94_L	110_L	0.756	1.00
276_F	409_F	0.754	1.00
344_G	347_L	0.754	1.00
339_M	375_V	0.753	1.00
27_A	149_A	0.753	1.00
430_L	433_Y	0.750	1.00
264_K	269_T	0.749	1.00
213_S	239_A	0.749	1.00
158_G	305_G	0.747	1.00
242_G	245_S	0.746	1.00
125_V	129_L	0.746	1.00
307_I	310_P	0.745	1.00
36_A	40_I	0.745	1.00
182_I	185_A	0.745	1.00
234_G	237_A	0.744	1.00
175_P	179_I	0.743	1.00
203_G	250_E	0.740	1.00
216_L	235_L	0.738	1.00
86_I	90_A	0.738	1.00
330_G	334_Q	0.736	1.00
60_T	113_I	0.736	1.00
429_K	432_P	0.735	1.00
228_D	231_Q	0.735	1.00
317_I	320_I	0.734	1.00
202_A	205_F	0.728	1.00
77_R	124_I	0.726	1.00
337_T	340_L	0.726	1.00
147_G	315_M	0.725	1.00
274_I	339_M	0.725	1.00
251_S	264_K	0.725	1.00
291_F	295_G	0.724	1.00
92_S	111_Q	0.721	1.00
374_L	378_I	0.718	1.00
380_T	399_S	0.715	1.00
18_G	184_I	0.712	1.00
107_F	110_L	0.709	1.00
240_L	243_I	0.707	1.00
22_A	118_M	0.707	1.00
63_T	204_I	0.707	1.00
58_L	407_G	0.706	1.00
341_V	367_I	0.706	1.00
95_C	98_A	0.702	1.00
37_M	54_T	0.700	1.00
89_M	178_I	0.698	1.00
19_L	129_L	0.697	1.00
204_I	257_I	0.696	1.00
168_W	171_Y	0.691	1.00
84_G	114_G	0.691	1.00
339_M	343_A	0.691	1.00
199_F	203_G	0.689	1.00
191_R	194_T	0.688	1.00
153_G	157_G	0.687	1.00
124_I	393_G	0.683	1.00
62_T	408_T	0.682	1.00
263_F	268_F	0.682	1.00
95_C	111_Q	0.681	1.00
274_I	379_L	0.681	1.00
175_P	178_I	0.681	1.00
190_G	194_T	0.679	1.00
290_P	304_S	0.678	1.00
340_L	343_A	0.678	1.00
226_A	229_S	0.674	1.00
58_L	408_T	0.673	1.00
140_G	144_A	0.671	1.00
72_A	124_I	0.671	1.00
207_M	211_V	0.670	1.00
123_M	142_F	0.670	1.00
413_M	416_A	0.670	1.00
384_Q	396_T	0.668	1.00
251_S	254_K	0.667	1.00
329_I	333_P	0.667	1.00
44_L	101_M	0.664	1.00
135_R	385_E	0.663	1.00
24_F	145_I	0.661	1.00
62_T	405_I	0.661	1.00
202_A	206_T	0.660	1.00
108_R	111_Q	0.659	1.00
287_T	411_I	0.651	1.00
229_S	233_L	0.648	1.00
139_Q	381_L	0.648	1.00
120_P	123_M	0.648	1.00
179_I	183_F	0.647	1.00
207_M	257_I	0.645	1.00
272_N	399_S	0.645	1.00
176_V	179_I	0.645	1.00
72_A	393_G	0.641	1.00
267_T	382_A	0.640	1.00
220_F	232_I	0.640	1.00
210_G	213_S	0.640	1.00
61_S	404_S	0.639	1.00
154_P	305_G	0.639	1.00
283_F	286_I	0.639	1.00
348_L	360_V	0.634	1.00
78_R	190_G	0.632	1.00
202_A	253_A	0.632	1.00
429_K	433_Y	0.631	1.00
146_Y	150_S	0.630	1.00
314_S	370_L	0.628	1.00
341_V	370_L	0.628	1.00
96_G	167_K	0.626	1.00
292_F	296_I	0.626	1.00
137_K	324_Q	0.625	1.00
307_I	362_T	0.624	1.00
25_F	173_N	0.624	1.00
38_P	42_G	0.623	1.00
124_I	396_T	0.623	1.00
92_S	174_L	0.622	1.00
40_I	161_V	0.622	1.00
226_A	232_I	0.621	1.00
13_T	137_K	0.621	1.00
159_W	164_L	0.621	1.00
267_T	270_F	0.619	1.00
32_I	172_I	0.618	1.00
246_F	258_L	0.617	1.00
326_V	381_L	0.617	1.00
229_S	234_G	0.613	1.00
42_G	45_G	0.612	1.00
352_L	364_F	0.611	1.00
220_F	231_Q	0.609	1.00
161_V	165_N	0.609	1.00
336_I	343_A	0.608	1.00
15_L	18_G	0.607	1.00
369_G	373_G	0.604	1.00
400_Q	403_R	0.604	1.00
148_L	152_I	0.604	1.00
29_D	108_R	0.603	1.00
299_V	358_K	0.602	1.00
210_G	244_V	0.602	1.00
194_T	197_I	0.602	1.00
139_Q	143_G	0.601	1.00
338_G	378_I	0.600	1.00
87_I	113_I	0.600	1.00
77_R	191_R	0.599	1.00
381_L	385_E	0.599	1.00
19_L	125_V	0.598	1.00
22_A	85_L	0.596	1.00
210_G	214_L	0.595	1.00
61_S	115_G	0.593	1.00
68_A	120_P	0.593	1.00
288_F	418_M	0.593	1.00
40_I	43_D	0.593	1.00
85_L	177_G	0.592	1.00
216_L	225_Y	0.591	1.00
97_M	103_E	0.591	1.00
334_Q	374_L	0.590	1.00
197_I	255_E	0.589	1.00
129_L	189_Q	0.589	1.00
342_M	345_G	0.587	1.00
149_A	154_P	0.586	1.00
223_K	227_W	0.585	1.00
65_V	400_Q	0.585	1.00
426_L	429_K	0.584	1.00
149_A	153_G	0.583	1.00
29_D	172_I	0.582	1.00
73_D	76_G	0.582	1.00
230_W	233_L	0.581	1.00
70_K	255_E	0.581	1.00
336_I	339_M	0.579	1.00
275_G	379_L	0.579	1.00
78_R	189_Q	0.577	1.00
191_R	196_P	0.577	1.00
221_G	225_Y	0.577	1.00
416_A	420_A	0.575	1.00
152_I	156_I	0.575	1.00
57_Y	88_F	0.574	1.00
77_R	125_V	0.573	1.00
217_A	221_G	0.572	1.00
133_K	136_A	0.572	1.00
426_L	434_L	0.571	1.00
321_I	325_L	0.571	1.00
171_Y	175_P	0.570	1.00
69_G	393_G	0.568	1.00
137_K	141_V	0.566	1.00
81_Y	125_V	0.566	1.00
302_S	306_T	0.566	1.00
314_S	362_T	0.563	1.00
326_V	330_G	0.562	1.00
171_Y	174_L	0.562	1.00
145_I	149_A	0.561	1.00
57_Y	108_R	0.561	1.00
206_T	210_G	0.558	1.00
221_G	232_I	0.558	1.00
25_F	85_L	0.556	1.00
64_I	67_I	0.555	1.00
130_F	134_Q	0.552	1.00
300_S	304_S	0.550	1.00
364_F	367_I	0.550	1.00
250_E	253_A	0.549	1.00
285_A	368_I	0.549	1.00
428_D	434_L	0.547	1.00
427_T	431_V	0.547	1.00
227_W	233_L	0.547	1.00
152_I	155_Q	0.546	1.00
256_P	259_P	0.545	1.00
88_F	114_G	0.545	1.00
348_L	367_I	0.544	1.00
62_T	404_S	0.543	1.00
309_T	313_I	0.543	1.00
60_T	114_G	0.541	1.00
335_I	379_L	0.541	1.00
13_T	138_F	0.541	1.00
250_E	257_I	0.540	1.00
282_M	372_M	0.538	1.00
384_Q	392_L	0.537	1.00
306_T	309_T	0.537	1.00
50_M	291_F	0.537	1.00
220_F	223_K	0.537	1.00
24_F	152_I	0.536	1.00
173_N	177_G	0.535	1.00
31_T	150_S	0.535	1.00
273_L	277_F	0.534	1.00
74_L	198_N	0.534	1.00
269_T	272_N	0.534	1.00
97_M	167_K	0.532	1.00
16_I	126_I	0.531	1.00
133_K	327_Y	0.531	1.00
411_I	415_G	0.530	1.00
27_A	150_S	0.530	1.00
31_T	153_G	0.530	1.00
24_F	28_L	0.530	1.00
52_W	59_L	0.530	1.00
41_V	47_L	0.529	1.00
279_S	403_R	0.528	1.00
135_R	403_R	0.527	1.00
296_I	354_L	0.527	1.00
75_L	199_F	0.527	1.00
55_T	415_G	0.526	1.00
34_G	287_T	0.526	1.00
314_S	317_I	0.526	1.00
309_T	312_M	0.525	1.00
426_L	433_Y	0.524	1.00
410_G	413_M	0.524	1.00
392_L	396_T	0.523	1.00
80_V	121_M	0.523	1.00
43_D	166_W	0.520	1.00
29_D	92_S	0.520	1.00
366_A	370_L	0.518	1.00
161_V	301_A	0.518	1.00
426_L	430_L	0.517	1.00
132_G	136_A	0.516	1.00
14_L	17_T	0.515	1.00
53_L	56_A	0.515	1.00
127_G	384_Q	0.515	1.00
160_I	169_V	0.514	1.00
375_V	379_L	0.513	1.00
375_V	378_I	0.513	1.00
155_Q	306_T	0.512	1.00
137_K	327_Y	0.511	1.00
143_G	319_S	0.511	1.00
239_A	242_G	0.510	1.00
15_L	125_V	0.509	1.00
25_F	29_D	0.509	1.00
185_A	189_Q	0.509	1.00
290_P	308_M	0.508	1.00
232_I	236_F	0.507	1.00
348_L	363_S	0.506	1.00
206_T	246_F	0.505	1.00
41_V	46_G	0.504	1.00
207_M	246_F	0.504	1.00
338_G	345_G	0.503	1.00
127_G	139_Q	0.501	1.00
50_M	53_L	0.501	1.00
325_L	328_K	0.500	1.00
206_T	209_V	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1pw4A	1	0.7652	100	0.465	Contact Map
4pypA	1	0.7634	100	0.48	Contact Map
3wdoA	1	0.8041	100	0.481	Contact Map
4j05A	3	0.7043	100	0.482	Contact Map
2gfpA	2	0.6913	100	0.501	Contact Map
4gc0A	1	0.8059	100	0.506	Contact Map
4zw9A	1	0.8022	100	0.516	Contact Map
3o7qA	1	0.7061	100	0.517	Contact Map
4tphA	2	0.7782	100	0.518	Contact Map
4ldsA	2	0.756	100	0.525	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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