FADE - BACSU - GREMLIN Contacts

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FADE - Probable acyl-CoA dehydrogenase

UniProt:	O32176	Sequences: MAKKAADVQKGGGFLIEDVTYDQMYTPEDFTDEHKMIAKTTEDYIEQDVLPHIDDIENHQFEHSVRLLKKAGELGLLGADVPEEYGGLGLDKISSALITEKFSRAGSFSLSYGAHVGIGSLPIVFFGSEEQKKKYLPGLASGEKIAAYALTEPGSGSDALGAKTTAVLNEAGTHYVLTGEKQWITNSAFADVFVVYAKVDGDKFSAFIVEKEFPGVSTGPEEKKMGIKGSSTRTLILDQAEVPKENLLGEIGKGHVIAFNILNIGRYKLAVGTIGASKRVIELSAAYANQRRQFKTPIAGFSLTQEKIGTMASRLYAMESSVYRTVGLFEDNMSQFTAEDLKDGRQIAKSIAEYAIECSLNKVFGSETLDYIVDEGVQIHGGYGFMQEYEVERAYRDSRINRIFEGTNEINRLIVPSTFLKKALKGELPLFEKAQSLQEELMMLMPEEPGSGVLEQEKYIVKQAKKIALFAAGLAAQKYGKAIDREQEILVNVADIVSNVYAMESAVLRTEKAIAAQGAEKAAQKVLYTEIFVQEAFNEIEAHAKESLIAMEEGDSLRMMLSALRKLTRVTPKNVIQKKREAAAGIFEAEKYTV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	594 (500)
Sequences:	5446 (3130)
Seq/√Len:	140.0

ECOLI - AIDB CAIA
BACSU - FADE
HALSA - Q9HS75 Q9HRI6
SULSO - Q97XW3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
138_G	143_E	6.351	1.00
129_E	133_K	5.570	1.00
169_N	176_V	3.790	1.00
178_T	239_Q	3.784	1.00
54_D	58_N	3.544	1.00
205_S	247_L	3.448	1.00
129_E	132_K	3.367	1.00
376_G	391_V	3.239	1.00
69_K	73_E	3.099	1.00
285_A	312_A	3.041	1.00
199_V	251_I	3.024	1.00
387_Q	392_E	2.966	1.00
42_E	46_E	2.940	1.00
250_E	253_K	2.836	1.00
131_Q	208_I	2.816	1.00
468_A	489_I	2.811	1.00
82_P	124_V	2.703	1.00
169_N	174_H	2.686	1.00
325_T	361_N	2.629	1.00
126_F	260_N	2.609	1.00
127_G	131_Q	2.574	1.00
188_A	218_T	2.419	1.00
297_P	300_G	2.408	1.00
128_S	131_Q	2.387	1.00
367_E	408_N	2.335	1.00
171_A	174_H	2.330	1.00
217_S	238_D	2.317	1.00
183_W	386_M	2.298	1.00
370_D	402_R	2.289	1.00
460_I	467_I	2.264	1.00
280_V	373_V	2.253	1.00
318_M	365_G	2.229	1.00
40_T	43_D	2.168	1.00
48_D	70_K	2.155	1.00
65_V	69_K	2.151	1.00
63_H	221_E	2.138	1.00
286_A	290_Q	2.124	1.00
83_E	89_G	2.107	1.00
253_K	256_V	2.099	1.00
174_H	241_E	2.085	1.00
162_A	198_K	2.077	1.00
277_S	372_I	2.072	1.00
157_S	410_I	2.001	1.00
168_L	251_I	1.952	1.00
310_T	375_E	1.939	1.00
277_S	315_L	1.929	1.00
133_K	137_P	1.918	1.00
55_D	59_H	1.916	1.00
288_A	379_I	1.903	1.00
414_I	418_T	1.890	1.00
219_G	236_I	1.853	1.00
370_D	395_Y	1.833	1.00
227_I	400_I	1.822	1.00
180_E	236_I	1.817	1.00
344_G	347_I	1.816	1.00
123_I	208_I	1.813	1.00
464_A	467_I	1.775	1.00
307_K	375_E	1.762	1.00
435_Q	465_K	1.739	1.00
138_G	144_K	1.728	1.00
151_T	183_W	1.687	1.00
342_K	347_I	1.679	1.00
310_T	531_I	1.654	1.00
321_S	361_N	1.653	1.00
44_Y	74_L	1.643	1.00
374_D	395_Y	1.643	1.00
313_S	528_Y	1.630	1.00
176_V	244_K	1.626	1.00
123_I	139_L	1.623	1.00
52_H	55_D	1.612	1.00
134_K	138_G	1.606	1.00
311_M	372_I	1.605	1.00
111_S	231_S	1.604	1.00
296_T	300_G	1.601	1.00
176_V	239_Q	1.597	1.00
216_V	235_L	1.588	1.00
174_H	244_K	1.583	1.00
159_A	255_H	1.583	1.00
289_N	299_A	1.568	1.00
43_D	47_Q	1.565	1.00
317_A	498_S	1.561	1.00
433_K	436_S	1.548	1.00
217_S	236_I	1.542	1.00
208_I	248_L	1.539	1.00
162_A	204_F	1.532	1.00
467_I	472_A	1.512	1.00
207_F	242_V	1.511	1.00
280_V	376_G	1.509	1.00
165_T	178_T	1.502	1.00
41_T	98_I	1.498	1.00
414_I	419_F	1.497	1.00
281_I	315_L	1.497	1.00
430_L	434_A	1.495	1.00
197_A	207_F	1.487	1.00
457_E	460_I	1.483	1.00
149_A	237_L	1.480	1.00
303_L	409_E	1.478	1.00
132_K	136_L	1.478	1.00
270_A	361_N	1.476	1.00
283_L	394_A	1.476	1.00
69_K	72_G	1.475	1.00
292_R	297_P	1.466	1.00
279_R	394_A	1.465	1.00
298_I	304_T	1.462	1.00
58_N	387_Q	1.461	1.00
66_R	69_K	1.458	1.00
213_F	216_V	1.456	1.00
175_Y	199_V	1.455	1.00
371_Y	375_E	1.454	1.00
115_H	139_L	1.444	1.00
44_Y	70_K	1.440	1.00
503_M	533_V	1.436	1.00
34_H	94_S	1.430	1.00
247_L	251_I	1.428	1.00
383_Y	389_Y	1.422	1.00
49_V	106_G	1.421	1.00
465_K	469_L	1.416	1.00
138_G	141_S	1.411	1.00
415_V	419_F	1.405	1.00
273_T	366_S	1.403	1.00
215_G	240_A	1.403	1.00
97_L	323_Y	1.403	1.00
170_E	200_D	1.402	1.00
363_V	408_N	1.394	1.00
49_V	108_F	1.388	1.00
180_E	234_T	1.387	1.00
450_G	457_E	1.385	1.00
327_G	331_D	1.373	1.00
209_V	245_E	1.373	1.00
53_I	393_R	1.370	1.00
81_V	140_A	1.370	1.00
315_L	372_I	1.362	1.00
178_T	238_D	1.360	1.00
174_H	246_N	1.358	1.00
223_K	387_Q	1.356	1.00
374_D	402_R	1.350	1.00
461_V	467_I	1.341	1.00
215_G	239_Q	1.332	1.00
370_D	374_D	1.326	1.00
145_I	190_A	1.322	1.00
513_A	522_A	1.320	1.00
82_P	85_Y	1.318	1.00
371_Y	374_D	1.313	1.00
177_L	207_F	1.312	1.00
122_P	194_V	1.309	1.00
279_R	283_L	1.309	1.00
307_K	409_E	1.303	1.00
463_Q	467_I	1.301	1.00
153_P	180_E	1.299	1.00
68_L	72_G	1.297	1.00
137_P	141_S	1.296	1.00
193_F	211_K	1.293	1.00
223_K	228_K	1.290	1.00
462_K	466_K	1.285	1.00
119_G	139_L	1.285	1.00
167_V	178_T	1.278	1.00
281_I	285_A	1.274	1.00
343_D	347_I	1.266	1.00
85_Y	132_K	1.259	1.00
288_A	304_T	1.254	1.00
240_A	243_P	1.244	1.00
222_E	232_T	1.243	1.00
374_D	377_V	1.241	1.00
511_E	515_A	1.238	1.00
453_V	456_Q	1.235	1.00
429_P	433_K	1.234	1.00
45_I	102_F	1.230	1.00
469_L	473_G	1.230	1.00
219_G	234_T	1.230	1.00
360_L	498_S	1.219	1.00
79_A	88_L	1.214	1.00
41_T	44_Y	1.212	1.00
304_T	307_K	1.210	1.00
402_R	408_N	1.210	1.00
437_L	441_L	1.204	1.00
414_I	417_S	1.202	1.00
102_F	109_S	1.201	1.00
169_N	244_K	1.200	1.00
287_Y	383_Y	1.197	1.00
130_E	134_K	1.192	1.00
373_V	394_A	1.184	1.00
513_A	523_A	1.182	1.00
377_V	395_Y	1.182	1.00
59_H	62_E	1.181	1.00
225_M	395_Y	1.177	1.00
149_A	193_F	1.175	1.00
84_E	133_K	1.174	1.00
41_T	45_I	1.173	1.00
463_Q	466_K	1.173	1.00
464_A	496_I	1.172	1.00
134_K	245_E	1.172	1.00
311_M	376_G	1.168	0.99
110_L	185_T	1.167	0.99
41_T	46_E	1.165	0.99
158_D	161_G	1.164	0.99
36_M	40_T	1.162	0.99
72_G	77_L	1.160	0.99
276_A	398_S	1.158	0.99
80_D	95_S	1.153	0.99
96_A	326_V	1.150	0.99
218_T	235_L	1.149	0.99
274_I	315_L	1.145	0.99
61_F	64_S	1.143	0.99
510_T	513_A	1.140	0.99
450_G	454_L	1.139	0.99
177_L	245_E	1.138	0.99
316_Y	525_K	1.134	0.99
363_V	367_E	1.133	0.99
369_L	401_N	1.127	0.99
328_L	350_S	1.126	0.99
225_M	392_E	1.124	0.99
283_L	380_H	1.120	0.99
84_E	129_E	1.116	0.99
351_I	355_A	1.114	0.99
187_S	235_L	1.114	0.99
452_G	456_Q	1.112	0.99
35_K	39_K	1.106	0.99
380_H	391_V	1.106	0.99
280_V	391_V	1.104	0.99
508_L	512_K	1.100	0.99
183_W	383_Y	1.100	0.99
104_R	278_K	1.099	0.99
79_A	98_I	1.099	0.99
450_G	453_V	1.093	0.99
147_A	184_I	1.093	0.99
539_E	543_H	1.092	0.99
530_E	534_Q	1.091	0.99
192_V	208_I	1.090	0.99
179_G	235_L	1.081	0.99
430_L	497_V	1.075	0.99
451_S	455_E	1.073	0.99
317_A	502_A	1.072	0.99
499_N	539_E	1.071	0.99
44_Y	48_D	1.070	0.99
70_K	73_E	1.069	0.99
461_V	465_K	1.069	0.99
344_G	348_A	1.068	0.99
176_V	241_E	1.066	0.99
332_N	351_I	1.063	0.99
374_D	399_R	1.063	0.99
194_V	206_A	1.063	0.99
349_K	433_K	1.060	0.99
438_Q	441_L	1.060	0.99
38_A	97_L	1.053	0.99
220_P	234_T	1.052	0.99
135_Y	246_N	1.051	0.99
157_S	294_F	1.040	0.99
363_V	490_L	1.038	0.99
317_A	532_F	1.030	0.99
459_Y	463_Q	1.030	0.99
456_Q	459_Y	1.030	0.99
163_K	166_A	1.027	0.99
373_V	395_Y	1.026	0.99
166_A	197_A	1.025	0.99
130_E	133_K	1.024	0.99
460_I	468_A	1.017	0.99
415_V	418_T	1.015	0.99
274_I	318_M	1.015	0.99
331_D	350_S	1.013	0.99
55_D	229_G	1.011	0.99
468_A	471_A	1.008	0.99
453_V	457_E	1.008	0.99
278_K	282_E	1.005	0.98
467_I	471_A	1.004	0.98
313_S	531_I	1.003	0.98
175_Y	207_F	1.002	0.98
451_S	454_L	1.001	0.98
439_E	442_M	1.000	0.98
278_K	319_E	0.998	0.98
470_F	474_L	0.993	0.98
55_D	58_N	0.992	0.98
143_E	191_D	0.990	0.98
460_I	463_Q	0.988	0.98
304_T	379_I	0.986	0.98
454_L	457_E	0.984	0.98
441_L	503_M	0.980	0.98
177_L	237_L	0.978	0.98
85_Y	133_K	0.976	0.98
262_L	265_G	0.973	0.98
521_K	525_K	0.967	0.98
430_L	433_K	0.966	0.98
368_T	371_Y	0.965	0.98
56_I	106_G	0.965	0.98
437_L	507_V	0.959	0.98
502_A	505_S	0.957	0.98
460_I	464_A	0.954	0.98
267_Y	361_N	0.953	0.98
367_E	491_V	0.950	0.98
277_S	369_L	0.950	0.98
506_A	529_T	0.948	0.98
320_S	505_S	0.946	0.98
169_N	172_G	0.946	0.98
68_L	77_L	0.946	0.98
514_I	522_A	0.945	0.98
156_G	405_E	0.945	0.98
130_E	245_E	0.942	0.98
349_K	429_P	0.942	0.98
187_S	233_R	0.936	0.98
194_V	261_I	0.934	0.98
523_A	526_V	0.930	0.97
380_H	390_E	0.929	0.97
274_I	322_V	0.928	0.97
238_D	243_P	0.925	0.97
468_A	474_L	0.925	0.97
70_K	74_L	0.923	0.97
324_R	501_Y	0.922	0.97
389_Y	392_E	0.922	0.97
178_T	215_G	0.922	0.97
412_R	486_E	0.920	0.97
352_A	429_P	0.920	0.97
195_V	237_L	0.919	0.97
452_G	455_E	0.918	0.97
435_Q	461_V	0.914	0.97
318_M	372_I	0.908	0.97
449_P	452_G	0.906	0.97
318_M	368_T	0.901	0.97
242_V	246_N	0.900	0.97
467_I	475_A	0.899	0.97
503_M	536_A	0.898	0.97
314_R	368_T	0.893	0.97
416_P	419_F	0.892	0.97
145_I	191_D	0.888	0.97
53_I	56_I	0.884	0.97
449_P	456_Q	0.883	0.97
49_V	53_I	0.883	0.97
544_A	548_L	0.880	0.96
36_M	39_K	0.875	0.96
364_F	368_T	0.875	0.96
215_G	238_D	0.872	0.96
48_D	66_R	0.872	0.96
284_S	379_I	0.871	0.96
461_V	472_A	0.870	0.96
81_V	120_S	0.869	0.96
183_W	287_Y	0.869	0.96
321_S	502_A	0.869	0.96
360_L	494_A	0.867	0.96
131_Q	246_N	0.867	0.96
213_F	240_A	0.866	0.96
314_R	317_A	0.865	0.96
130_E	135_Y	0.864	0.96
356_I	493_V	0.863	0.96
499_N	533_V	0.861	0.96
58_N	62_E	0.859	0.96
541_E	545_K	0.858	0.96
221_E	231_S	0.857	0.96
522_A	525_K	0.857	0.96
352_A	422_K	0.851	0.96
107_S	229_G	0.850	0.96
463_Q	470_F	0.850	0.96
512_K	522_A	0.848	0.96
131_Q	135_Y	0.846	0.96
522_A	526_V	0.845	0.96
131_Q	248_L	0.845	0.96
536_A	539_E	0.845	0.96
283_L	390_E	0.844	0.96
432_E	436_S	0.840	0.95
457_E	471_A	0.839	0.95
170_E	174_H	0.839	0.95
447_E	450_G	0.838	0.95
185_T	230_S	0.838	0.95
523_A	527_L	0.835	0.95
131_Q	249_G	0.834	0.95
442_M	458_K	0.834	0.95
151_T	182_Q	0.832	0.95
466_K	470_F	0.830	0.95
120_S	140_A	0.830	0.95
84_E	89_G	0.826	0.95
113_G	185_T	0.826	0.95
37_I	88_L	0.820	0.95
440_E	444_L	0.820	0.95
456_Q	460_I	0.818	0.95
366_S	408_N	0.818	0.95
317_A	506_A	0.817	0.95
238_D	241_E	0.816	0.95
284_S	376_G	0.816	0.95
48_D	51_P	0.815	0.95
324_R	508_L	0.815	0.95
103_S	109_S	0.815	0.95
155_S	162_A	0.815	0.95
461_V	468_A	0.809	0.94
45_I	49_V	0.808	0.94
53_I	57_E	0.807	0.94
210_E	213_F	0.807	0.94
110_L	113_G	0.806	0.94
364_F	498_S	0.806	0.94
310_T	314_R	0.805	0.94
504_E	508_L	0.805	0.94
198_K	202_D	0.805	0.94
536_A	540_I	0.803	0.94
443_M	446_P	0.802	0.94
324_R	505_S	0.801	0.94
271_V	322_V	0.800	0.94
281_I	312_A	0.800	0.94
324_R	327_G	0.799	0.94
259_F	263_N	0.798	0.94
437_L	500_V	0.796	0.94
460_I	474_L	0.796	0.94
279_R	390_E	0.796	0.94
449_P	454_L	0.795	0.94
495_D	539_E	0.794	0.94
408_N	487_Q	0.792	0.94
284_S	311_M	0.789	0.94
324_R	328_L	0.786	0.93
280_V	284_S	0.786	0.93
526_V	530_E	0.784	0.93
104_R	279_R	0.784	0.93
457_E	474_L	0.782	0.93
345_R	349_K	0.782	0.93
58_N	61_F	0.781	0.93
167_V	200_D	0.779	0.93
164_T	168_L	0.779	0.93
377_V	391_V	0.778	0.93
399_R	402_R	0.778	0.93
34_H	37_I	0.777	0.93
532_F	536_A	0.777	0.93
352_A	426_G	0.776	0.93
440_E	443_M	0.775	0.93
166_A	207_F	0.775	0.93
111_S	186_N	0.775	0.93
215_G	242_V	0.774	0.93
450_G	456_Q	0.772	0.93
455_E	459_Y	0.772	0.93
495_D	543_H	0.772	0.93
492_N	547_S	0.770	0.93
491_V	495_D	0.767	0.93
49_V	102_F	0.766	0.93
467_I	492_N	0.764	0.92
218_T	233_R	0.761	0.92
413_L	486_E	0.761	0.92
348_A	352_A	0.761	0.92
538_N	541_E	0.761	0.92
364_F	494_A	0.760	0.92
227_I	404_F	0.760	0.92
392_E	396_R	0.758	0.92
39_K	43_D	0.754	0.92
50_L	394_A	0.753	0.92
435_Q	462_K	0.753	0.92
226_G	397_D	0.751	0.92
429_P	432_E	0.750	0.92
49_V	52_H	0.749	0.92
509_R	513_A	0.744	0.91
61_F	221_E	0.744	0.91
243_P	246_N	0.743	0.91
224_K	382_G	0.743	0.91
460_I	471_A	0.741	0.91
329_F	354_Y	0.740	0.91
422_K	426_G	0.740	0.91
52_H	56_I	0.740	0.91
234_T	388_E	0.739	0.91
310_T	536_A	0.739	0.91
282_E	286_A	0.736	0.91
468_A	472_A	0.732	0.91
539_E	542_A	0.731	0.91
347_I	350_S	0.729	0.91
383_Y	386_M	0.729	0.91
40_T	74_L	0.729	0.91
159_A	294_F	0.729	0.91
169_N	241_E	0.729	0.91
525_K	529_T	0.727	0.91
467_I	470_F	0.727	0.91
543_H	546_E	0.725	0.90
437_L	440_E	0.724	0.90
510_T	514_I	0.724	0.90
457_E	468_A	0.723	0.90
540_I	543_H	0.722	0.90
239_Q	243_P	0.721	0.90
449_P	453_V	0.720	0.90
320_S	509_R	0.720	0.90
540_I	547_S	0.719	0.90
163_K	167_V	0.719	0.90
432_E	435_Q	0.719	0.90
370_D	398_S	0.719	0.90
85_Y	129_E	0.719	0.90
380_H	389_Y	0.718	0.90
353_E	433_K	0.718	0.90
168_L	171_A	0.716	0.90
508_L	522_A	0.714	0.90
509_R	522_A	0.713	0.90
120_S	139_L	0.711	0.90
342_K	345_R	0.710	0.89
356_I	360_L	0.708	0.89
321_S	501_Y	0.707	0.89
510_T	529_T	0.707	0.89
50_L	53_I	0.697	0.89
126_F	257_I	0.697	0.89
382_G	405_E	0.695	0.88
309_G	312_A	0.695	0.88
450_G	468_A	0.694	0.88
438_Q	442_M	0.693	0.88
276_A	369_L	0.693	0.88
180_E	219_G	0.692	0.88
42_E	47_Q	0.692	0.88
266_R	382_G	0.688	0.88
454_L	458_K	0.688	0.88
50_L	105_A	0.687	0.88
147_A	193_F	0.685	0.88
452_G	534_Q	0.682	0.88
114_A	146_A	0.682	0.88
314_R	371_Y	0.682	0.88
303_L	491_V	0.682	0.88
273_T	369_L	0.681	0.87
435_Q	439_E	0.680	0.87
478_K	481_K	0.680	0.87
42_E	45_I	0.676	0.87
452_G	458_K	0.675	0.87
428_L	469_L	0.673	0.87
432_E	465_K	0.672	0.87
114_A	118_I	0.671	0.87
497_V	501_Y	0.671	0.87
178_T	241_E	0.671	0.87
543_H	547_S	0.671	0.87
155_S	161_G	0.670	0.87
193_F	235_L	0.669	0.87
373_V	398_S	0.669	0.87
53_I	58_N	0.668	0.86
53_I	394_A	0.667	0.86
41_T	74_L	0.667	0.86
75_G	78_G	0.666	0.86
145_I	189_F	0.664	0.86
374_D	378_Q	0.664	0.86
493_V	497_V	0.663	0.86
400_I	404_F	0.663	0.86
395_Y	399_R	0.663	0.86
204_F	255_H	0.660	0.86
356_I	427_E	0.660	0.86
461_V	464_A	0.658	0.86
286_A	289_N	0.657	0.86
429_P	435_Q	0.656	0.85
151_T	291_R	0.655	0.85
463_Q	469_L	0.655	0.85
43_D	48_D	0.654	0.85
464_A	472_A	0.654	0.85
128_S	132_K	0.652	0.85
225_M	391_V	0.650	0.85
513_A	525_K	0.649	0.85
378_Q	399_R	0.647	0.85
78_G	81_V	0.646	0.85
107_S	110_L	0.644	0.84
56_I	229_G	0.644	0.84
167_V	176_V	0.642	0.84
374_D	398_S	0.641	0.84
311_M	315_L	0.641	0.84
255_H	259_F	0.638	0.84
401_N	404_F	0.637	0.84
434_A	461_V	0.636	0.84
506_A	532_F	0.636	0.84
471_A	474_L	0.635	0.84
183_W	232_T	0.635	0.84
439_E	443_M	0.635	0.84
225_M	384_G	0.634	0.83
542_A	546_E	0.634	0.83
496_I	540_I	0.633	0.83
222_E	230_S	0.631	0.83
179_G	193_F	0.630	0.83
40_T	76_L	0.628	0.83
466_K	471_A	0.628	0.83
499_N	537_F	0.627	0.83
442_M	446_P	0.625	0.83
210_E	246_N	0.624	0.83
164_T	167_V	0.624	0.83
460_I	473_G	0.623	0.82
488_E	535_E	0.623	0.82
123_I	248_L	0.621	0.82
538_N	542_A	0.621	0.82
507_V	511_E	0.620	0.82
303_L	306_E	0.619	0.82
283_L	391_V	0.617	0.82
264_I	268_K	0.616	0.82
277_S	373_V	0.613	0.81
393_R	397_D	0.613	0.81
53_I	106_G	0.612	0.81
377_V	380_H	0.612	0.81
462_K	465_K	0.612	0.81
42_E	101_K	0.610	0.81
183_W	222_E	0.609	0.81
512_K	515_A	0.608	0.81
45_I	101_K	0.608	0.81
280_V	394_A	0.608	0.81
285_A	289_N	0.607	0.81
455_E	458_K	0.607	0.81
515_A	522_A	0.607	0.81
257_I	260_N	0.605	0.81
227_I	230_S	0.605	0.81
393_R	396_R	0.603	0.80
199_V	252_G	0.603	0.80
364_F	499_N	0.602	0.80
506_A	509_R	0.602	0.80
521_K	524_Q	0.602	0.80
318_M	364_F	0.602	0.80
66_R	70_K	0.601	0.80
531_I	536_A	0.601	0.80
92_K	95_S	0.600	0.80
118_I	265_G	0.600	0.80
209_V	237_L	0.600	0.80
460_I	472_A	0.600	0.80
131_Q	134_K	0.599	0.80
452_G	530_E	0.598	0.80
360_L	493_V	0.597	0.80
148_Y	265_G	0.597	0.80
441_L	446_P	0.597	0.80
470_F	473_G	0.596	0.80
199_V	247_L	0.592	0.79
428_L	432_E	0.592	0.79
110_L	227_I	0.592	0.79
368_T	372_I	0.591	0.79
96_A	99_T	0.591	0.79
184_I	187_S	0.590	0.79
349_K	353_E	0.589	0.79
84_E	130_E	0.588	0.79
113_G	268_K	0.587	0.79
500_V	504_E	0.586	0.78
284_S	391_V	0.585	0.78
74_L	77_L	0.585	0.78
224_K	232_T	0.585	0.78
38_A	101_K	0.584	0.78
219_G	239_Q	0.583	0.78
154_G	163_K	0.582	0.78
135_Y	192_V	0.579	0.78
310_T	371_Y	0.579	0.78
431_F	434_A	0.579	0.78
459_Y	468_A	0.578	0.77
121_L	264_I	0.577	0.77
128_S	248_L	0.576	0.77
386_M	390_E	0.576	0.77
163_K	179_G	0.576	0.77
370_D	399_R	0.575	0.77
68_L	145_I	0.574	0.77
187_S	193_F	0.574	0.77
284_S	380_H	0.573	0.77
328_L	353_E	0.573	0.77
177_L	209_V	0.571	0.77
464_A	470_F	0.571	0.77
148_Y	262_L	0.571	0.77
332_N	354_Y	0.571	0.77
444_L	447_E	0.570	0.77
276_A	373_V	0.570	0.77
195_V	209_V	0.568	0.76
465_K	473_G	0.567	0.76
308_I	376_G	0.567	0.76
122_P	261_I	0.567	0.76
111_S	145_I	0.566	0.76
167_V	170_E	0.566	0.76
278_K	315_L	0.565	0.76
184_I	400_I	0.565	0.76
96_A	271_V	0.564	0.76
168_L	175_Y	0.564	0.76
150_L	204_F	0.564	0.76
531_I	535_E	0.562	0.76
40_T	44_Y	0.562	0.76
127_G	132_K	0.561	0.75
124_V	132_K	0.561	0.75
120_S	123_I	0.561	0.75
206_A	210_E	0.560	0.75
311_M	375_E	0.560	0.75
276_A	401_N	0.559	0.75
83_E	124_V	0.559	0.75
216_V	240_A	0.558	0.75
215_G	244_K	0.558	0.75
37_I	40_T	0.558	0.75
467_I	474_L	0.557	0.75
461_V	471_A	0.557	0.75
367_E	402_R	0.556	0.75
355_A	358_C	0.556	0.75
448_E	457_E	0.553	0.74
454_L	460_I	0.553	0.74
44_Y	51_P	0.553	0.74
44_Y	47_Q	0.552	0.74
496_I	499_N	0.552	0.74
503_M	507_V	0.551	0.74
157_S	293_Q	0.551	0.74
288_A	298_I	0.550	0.74
180_E	383_Y	0.550	0.74
178_T	240_A	0.549	0.74
91_D	94_S	0.548	0.74
452_G	459_Y	0.548	0.74
302_S	483_I	0.546	0.73
267_Y	358_C	0.546	0.73
316_Y	528_Y	0.543	0.73
135_Y	208_I	0.542	0.73
49_V	105_A	0.542	0.73
320_S	506_A	0.542	0.73
208_I	257_I	0.542	0.73
371_Y	539_E	0.542	0.73
153_P	182_Q	0.542	0.73
92_K	103_S	0.541	0.73
448_E	454_L	0.540	0.73
463_Q	540_I	0.539	0.72
71_A	74_L	0.539	0.72
47_Q	51_P	0.539	0.72
55_D	66_R	0.538	0.72
413_L	487_Q	0.536	0.72
224_K	385_F	0.536	0.72
81_V	85_Y	0.535	0.72
376_G	379_I	0.535	0.72
437_L	444_L	0.534	0.72
385_F	392_E	0.534	0.72
433_K	437_L	0.534	0.72
462_K	469_L	0.533	0.72
67_L	70_K	0.530	0.71
502_A	506_A	0.529	0.71
196_Y	206_A	0.528	0.71
151_T	406_G	0.528	0.71
101_K	104_R	0.527	0.71
487_Q	490_L	0.526	0.71
227_I	272_G	0.525	0.71
119_G	146_A	0.525	0.71
321_S	497_V	0.525	0.71
437_L	442_M	0.524	0.70
63_H	218_T	0.523	0.70
380_H	383_Y	0.522	0.70
373_V	391_V	0.522	0.70
226_G	385_F	0.522	0.70
328_L	331_D	0.522	0.70
100_E	278_K	0.521	0.70
459_Y	462_K	0.519	0.70
263_N	358_C	0.519	0.70
212_E	218_T	0.519	0.70
135_Y	138_G	0.519	0.70
80_D	92_K	0.518	0.70
463_Q	474_L	0.518	0.70
151_T	405_E	0.517	0.69
54_D	387_Q	0.516	0.69
469_L	472_A	0.515	0.69
498_S	502_A	0.515	0.69
320_S	501_Y	0.513	0.69
59_H	63_H	0.513	0.69
106_G	113_G	0.512	0.69
327_G	504_E	0.511	0.68
368_T	491_V	0.511	0.68
71_A	77_L	0.509	0.68
286_A	380_H	0.508	0.68
537_F	541_E	0.508	0.68
294_F	301_F	0.507	0.68
80_D	89_G	0.507	0.68
77_L	81_V	0.506	0.68
463_Q	468_A	0.506	0.68
145_I	186_N	0.506	0.68
353_E	357_E	0.506	0.68
43_D	165_T	0.504	0.67
104_R	107_S	0.503	0.67
366_S	401_N	0.503	0.67
441_L	507_V	0.502	0.67
310_T	313_S	0.502	0.67
71_A	102_F	0.502	0.67
107_S	228_K	0.502	0.67
160_L	198_K	0.502	0.67
78_G	124_V	0.501	0.67
435_Q	438_Q	0.501	0.67
313_S	317_A	0.500	0.67
224_K	405_E	0.500	0.67

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3owaA	3	0.9865	100	0.298	Contact Map
2z1qA	2	0.9209	100	0.327	Contact Map
2uxwA	2	0.9057	100	0.334	Contact Map
1w07A	2	0.9343	100	0.363	Contact Map
2ddhA	2	0.899	100	0.378	Contact Map
4y9jA	4	0.8838	100	0.452	Contact Map
2jifA	4	0.633	100	0.478	Contact Map
4l1fA	4	0.6313	100	0.478	Contact Map
2d29A	4	0.6347	100	0.48	Contact Map
1bucA	4	0.6313	100	0.482	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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