METN - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

METN - Methionine import ATP-binding protein MetN

UniProt:	O32169	Sequences: MINLQDVSKVYKSKHGDVNAVQNVSLSIKKGEIFGIIGYSGAGKSSLIRLLNGLEKPTSGTVEVAGTKINEVNGRGLRKARHEISMIFQHFNLLWSRTVRDNIMFPLEIAGVKKSERIKRANELIKLVGLEGKEKSYPSQLSGGQKQRVGIARALANNPKVLLCDEATSALDPQTTDSILDLLSDINERLGLTIVLITHEMHVIRKICNRVAVMENGKVVEEGEVLDVFKNPKEQMTKRFVQQVTEPEETKETLQHLLDDTASGKMVQLTFVGESAEQPLITEMIRNFNVSVNILQGKISQTKDGAYGSLFIHIDGDEEEVQNVIRFINDKQVKAEVITNV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	341 (264)
Sequences:	27565 (18529)
Seq/√Len:	1140.4

ECOLI - METN PROV MALK POTG POTA FBPC YDCT CYSA UGPC YCJV YADG YHES YEHX DPPF OPPD DPPD MACB DDPD UUP OPPF RBSA SAPD MODC ARAG GSIA DDPF MLAF FEPC TAUB SAPF NIKE HISP YECC MDLB YTFR MDLA FHUC LSRA FECE CYDC MSBA GLNQ PHNC LPTB SSUB CYDD YHDZ GLTL FTSE YOJI YPHE ETTA PHNK LIVG LOLD SUFC MODF THIQ XYLG ZNUC ARTP PSTB ALSA LIVF BTUD YBBA MGLA NIKD FETA PHNL YEJF CCMA YBHF YDDA YNJD YBIT YHIH
BACSU - METN OPUBA OPUCA OPUAA YVRA YURJ OPPD MSMX YFIL YXLF YHAQ DPPD YHCH TAGH YDBJ YCBN YKFD APPD YFMR YDIF YVFR APPF OPPF YFMM YKPA YTRB RBSA ECFA1 FHUC YUSV YFMF YHEH TCYN BCEA YCLP YFIC YTLC YLMA ECSA NATA SUNT SKFE YXDL YFIB YGAD SUFC YVCR YKNV YKNU BMRA YHEI FTSE TCYC YXEO CYDD YWJA YKOD GLNQ YVRO ECFA2 ARTM CYDC SSUB YKNY MNTB YJKB PSTB1 ALBC YTHP PSTB2 YCLH ZNUC YYBJ EXPZ YHCG YUFO YTRE YYDI
HALSA - BTUDA Q9HMX3 Q9HMW0 Q9HHQ5 Q9HNZ9 Q9HMT3 Q9HMX2 Q9HR06 Q9HMU8 Q9HRJ6 Q9HMG1 Q9HRH8 PSTB2 PHNC Q9HSQ7 Q9HHM2 Q9HMG6 Q9HNY3 Q9HRZ9 Y2317 Y1631 Q9HRV7 Q9HR96 PSTB1 Q9HHR7 Q9HS04 Q9HT03 Q9HQA8 Q9HR21 Q9HMC1 Q9HMW1
SULSO - Q97UF2 Q97UY8 Q7LX64 Q97YY4 Q97VH6 Q97ZC0 Q97UH3 Q97VC1 Q97YP3 Q97VF5 Q97UJ9 Q97VK8 Q97X18 Q97YK2 Q97VF4 Q97YP7 Q97VK9 Q97YP8 Q97YQ7 Q97UD4 Q97Z03 Q97U54 Q980W0 Q97UH4 Y1893 Q97V01 PSTB Q97W42 Y2030 Q7LY07 Q97V00 Q7LXM4 Q97VY4 Q97VM2 Q7LX80 Q97UG5 Q97Z56 Q97YP4 Q97Z96 Q97UC2 Q97ZU0 Q980K5 Q980E6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
32_E	210_R	4.250	1.00
6_D	23_N	3.893	1.00
19_N	22_Q	3.791	1.00
5_Q	61_T	3.302	1.00
9_K	50_L	3.243	1.00
205_R	226_L	3.226	1.00
3_N	27_S	3.223	1.00
4_L	7_V	3.029	1.00
35_G	208_C	2.818	1.00
8_S	59_S	2.791	1.00
83_E	160_K	2.782	1.00
186_I	192_L	2.676	1.00
34_F	212_A	2.666	1.00
29_K	32_E	2.414	1.00
48_I	163_L	2.375	1.00
10_V	19_N	2.350	1.00
224_E	227_D	2.345	1.00
7_V	57_P	2.293	1.00
136_S	140_Q	2.247	1.00
223_G	227_D	2.247	1.00
48_I	197_I	2.245	1.00
3_N	63_E	2.185	1.00
22_Q	218_K	2.167	1.00
96_S	139_S	2.127	1.00
8_S	23_N	2.094	1.00
212_A	219_V	2.087	1.00
113_K	116_E	2.070	1.00
9_K	58_T	2.015	1.00
9_K	55_E	1.939	1.00
184_S	206_K	1.899	1.00
35_G	204_I	1.898	1.00
8_S	19_N	1.880	1.00
210_R	222_E	1.860	1.00
227_D	231_N	1.858	1.00
4_L	26_L	1.849	1.00
49_R	54_L	1.835	1.00
100_R	104_M	1.831	1.00
28_I	34_F	1.812	1.00
97_R	105_F	1.803	1.00
6_D	25_S	1.740	1.00
10_V	58_T	1.715	1.00
5_Q	63_E	1.703	1.00
97_R	101_D	1.676	1.00
100_R	134_E	1.669	1.00
26_L	212_A	1.655	1.00
30_K	160_K	1.644	1.00
198_T	204_I	1.622	1.00
50_L	57_P	1.611	1.00
98_T	101_D	1.596	1.00
99_V	141_L	1.596	1.00
120_R	158_N	1.595	1.00
65_A	160_K	1.590	1.00
120_R	123_E	1.583	1.00
97_R	102_N	1.515	1.00
133_K	136_S	1.491	1.00
8_S	22_Q	1.480	1.00
100_R	135_K	1.474	1.00
124_L	156_A	1.434	1.00
180_L	206_K	1.405	1.00
210_R	221_E	1.404	1.00
223_G	228_V	1.375	1.00
123_E	127_L	1.367	1.00
49_R	55_E	1.364	1.00
278_Q	282_T	1.360	1.00
4_L	51_L	1.343	1.00
122_N	134_E	1.338	1.00
138_P	149_V	1.334	1.00
280_L	284_M	1.329	1.00
52_N	163_L	1.324	1.00
11_Y	20_A	1.287	1.00
158_N	192_L	1.282	1.00
128_V	152_A	1.272	1.00
208_C	211_V	1.261	1.00
227_D	230_K	1.259	1.00
196_L	208_C	1.258	1.00
5_Q	25_S	1.250	1.00
141_L	149_V	1.250	1.00
11_Y	46_S	1.245	1.00
137_Y	140_Q	1.243	1.00
229_F	232_P	1.243	1.00
272_V	275_S	1.242	1.00
116_E	120_R	1.231	1.00
231_N	234_E	1.229	1.00
125_I	134_E	1.220	1.00
116_E	119_K	1.217	1.00
85_S	154_A	1.217	1.00
213_V	232_P	1.208	1.00
104_M	121_A	1.192	1.00
226_L	230_K	1.185	1.00
21_V	50_L	1.179	1.00
53_G	56_K	1.174	1.00
102_N	138_P	1.173	1.00
32_E	209_N	1.172	1.00
237_T	241_V	1.152	1.00
171_L	179_I	1.152	1.00
34_F	210_R	1.151	1.00
126_K	131_E	1.150	1.00
124_L	152_A	1.150	1.00
282_T	285_I	1.137	1.00
10_V	17_D	1.136	1.00
225_V	229_F	1.129	1.00
42_A	214_M	1.126	1.00
102_N	153_R	1.118	1.00
213_V	228_V	1.106	1.00
275_S	279_P	1.100	1.00
268_Q	272_V	1.095	1.00
114_K	117_R	1.091	1.00
276_A	279_P	1.087	1.00
238_K	242_Q	1.079	1.00
255_Q	259_D	1.075	1.00
119_K	123_E	1.073	1.00
183_L	194_I	1.070	1.00
85_S	159_P	1.064	1.00
52_N	86_M	1.060	1.00
278_Q	285_I	1.054	1.00
268_Q	271_F	1.049	1.00
274_E	278_Q	1.044	1.00
113_K	117_R	1.044	1.00
275_S	278_Q	1.036	1.00
271_F	275_S	1.035	1.00
21_V	24_V	1.030	1.00
269_L	272_V	1.025	1.00
264_G	267_V	1.019	1.00
94_L	97_R	1.015	1.00
180_L	203_V	1.015	1.00
117_R	121_A	1.015	1.00
101_D	104_M	1.014	1.00
6_D	59_S	1.012	1.00
87_I	154_A	1.011	1.00
51_L	195_V	1.009	1.00
212_A	222_E	1.005	1.00
122_N	130_L	0.992	1.00
98_T	102_N	0.986	1.00
271_F	274_E	0.983	1.00
118_I	122_N	0.983	1.00
33_I	194_I	0.974	1.00
5_Q	27_S	0.969	1.00
28_I	193_T	0.962	1.00
50_L	62_V	0.962	1.00
277_E	280_L	0.955	1.00
266_M	270_T	0.955	1.00
104_M	108_E	0.952	1.00
277_E	285_I	0.949	1.00
272_V	276_A	0.941	1.00
228_V	232_P	0.939	1.00
106_P	153_R	0.938	1.00
202_H	206_K	0.931	1.00
104_M	118_I	0.930	1.00
225_V	228_V	0.928	1.00
124_L	127_L	0.924	1.00
276_A	280_L	0.922	1.00
278_Q	284_M	0.922	1.00
7_V	50_L	0.922	1.00
281_I	285_I	0.921	1.00
229_F	233_K	0.915	1.00
4_L	62_V	0.915	1.00
265_K	268_Q	0.915	1.00
161_V	193_T	0.914	1.00
265_K	270_T	0.910	1.00
39_Y	42_A	0.908	1.00
267_V	270_T	0.892	1.00
36_I	47_L	0.891	1.00
127_L	185_D	0.890	1.00
34_F	222_E	0.889	1.00
258_L	261_T	0.888	1.00
105_F	108_E	0.886	1.00
284_M	288_F	0.884	1.00
163_L	195_V	0.882	1.00
215_E	218_K	0.876	1.00
24_V	47_L	0.872	1.00
26_L	47_L	0.867	1.00
243_Q	246_E	0.865	1.00
31_G	193_T	0.863	1.00
109_I	114_K	0.862	1.00
54_L	88_F	0.860	1.00
36_I	195_V	0.859	1.00
196_L	207_I	0.858	1.00
122_N	126_K	0.855	1.00
103_I	125_I	0.852	1.00
255_Q	258_L	0.845	1.00
103_I	156_A	0.840	1.00
100_R	121_A	0.836	1.00
34_F	195_V	0.835	1.00
95_W	139_S	0.832	1.00
282_T	286_R	0.832	1.00
9_K	46_S	0.830	1.00
50_L	55_E	0.829	1.00
259_D	262_A	0.828	1.00
87_I	164_C	0.827	1.00
257_L	260_D	0.826	1.00
89_Q	143_G	0.824	1.00
123_E	126_K	0.823	1.00
273_G	277_E	0.822	1.00
284_M	287_N	0.821	1.00
45_S	49_R	0.813	1.00
96_S	137_Y	0.809	1.00
181_D	184_S	0.809	1.00
264_G	268_Q	0.803	1.00
181_D	185_D	0.802	1.00
176_T	200_E	0.801	1.00
285_I	288_F	0.800	1.00
236_M	240_F	0.799	1.00
273_G	276_A	0.798	1.00
23_N	59_S	0.794	1.00
130_L	133_K	0.785	1.00
239_R	243_Q	0.781	1.00
251_K	254_L	0.778	1.00
244_V	248_E	0.773	1.00
104_M	117_R	0.772	1.00
50_L	58_T	0.772	1.00
131_E	134_E	0.770	1.00
241_V	245_T	0.769	1.00
278_Q	281_I	0.768	1.00
93_L	102_N	0.764	1.00
259_D	263_S	0.762	1.00
236_M	239_R	0.760	1.00
226_L	229_F	0.758	1.00
99_V	102_N	0.750	1.00
273_G	278_Q	0.749	1.00
283_E	286_R	0.745	1.00
168_T	179_I	0.743	1.00
114_K	118_I	0.743	1.00
234_E	238_K	0.742	1.00
166_E	199_H	0.742	1.00
277_E	282_T	0.740	1.00
256_H	259_D	0.736	1.00
261_T	264_G	0.731	1.00
100_R	103_I	0.729	1.00
23_N	218_K	0.728	1.00
244_V	247_P	0.726	1.00
230_K	233_K	0.724	1.00
258_L	262_A	0.724	1.00
266_M	269_L	0.724	1.00
240_F	243_Q	0.723	1.00
270_T	274_E	0.723	1.00
250_T	253_T	0.719	1.00
269_L	273_G	0.718	1.00
108_E	117_R	0.718	1.00
129_G	178_S	0.716	1.00
263_S	267_V	0.715	1.00
115_S	119_K	0.714	1.00
215_E	220_V	0.710	1.00
107_L	110_A	0.708	1.00
151_I	179_I	0.705	1.00
29_K	210_R	0.705	1.00
279_P	282_T	0.702	1.00
256_H	260_D	0.700	1.00
274_E	277_E	0.697	1.00
102_N	105_F	0.695	1.00
164_C	183_L	0.695	1.00
211_V	225_V	0.693	1.00
230_K	234_E	0.690	1.00
225_V	236_M	0.689	1.00
85_S	89_Q	0.688	1.00
267_V	271_F	0.684	1.00
64_V	82_H	0.683	1.00
28_I	161_V	0.682	1.00
257_L	261_T	0.681	1.00
265_K	269_L	0.680	1.00
257_L	262_A	0.677	1.00
182_L	185_D	0.676	1.00
262_A	275_S	0.672	1.00
183_L	207_I	0.671	1.00
94_L	102_N	0.670	1.00
254_L	258_L	0.670	1.00
47_L	214_M	0.670	1.00
276_A	282_T	0.670	1.00
280_L	283_E	0.670	1.00
83_E	157_N	0.669	1.00
239_R	242_Q	0.667	1.00
30_K	65_A	0.667	1.00
102_N	106_P	0.665	1.00
176_T	203_V	0.663	1.00
177_D	181_D	0.661	1.00
138_P	146_K	0.660	1.00
251_K	255_Q	0.659	1.00
254_L	257_L	0.659	1.00
22_Q	217_G	0.658	1.00
99_V	149_V	0.657	1.00
272_V	278_Q	0.657	1.00
277_E	281_I	0.657	1.00
24_V	219_V	0.654	1.00
270_T	273_G	0.650	1.00
6_D	9_K	0.648	1.00
268_Q	275_S	0.647	1.00
164_C	194_I	0.647	1.00
10_V	22_Q	0.646	1.00
84_I	161_V	0.644	1.00
240_F	244_V	0.644	1.00
270_T	278_Q	0.640	1.00
246_E	249_E	0.639	1.00
234_E	237_T	0.635	1.00
267_V	272_V	0.634	1.00
252_E	255_Q	0.634	1.00
248_E	251_K	0.633	1.00
95_W	146_K	0.630	1.00
260_D	263_S	0.627	1.00
265_K	271_F	0.626	1.00
65_A	83_E	0.625	1.00
275_S	282_T	0.625	1.00
87_I	147_Q	0.625	1.00
266_M	271_F	0.623	1.00
237_T	240_F	0.622	1.00
119_K	122_N	0.621	1.00
271_F	276_A	0.620	1.00
122_N	132_G	0.620	1.00
264_G	269_L	0.619	1.00
7_V	62_V	0.617	1.00
120_R	124_L	0.616	1.00
219_V	222_E	0.611	1.00
162_L	192_L	0.611	1.00
168_T	203_V	0.608	1.00
265_K	273_G	0.608	1.00
265_K	272_V	0.607	1.00
126_K	132_G	0.606	1.00
238_K	241_V	0.605	1.00
103_I	107_L	0.605	1.00
11_Y	55_E	0.605	1.00
161_V	195_V	0.604	1.00
159_P	186_I	0.603	1.00
279_P	283_E	0.600	1.00
37_I	213_V	0.599	1.00
65_A	82_H	0.598	1.00
250_T	254_L	0.597	1.00
117_R	120_R	0.597	1.00
283_E	287_N	0.596	1.00
103_I	106_P	0.592	1.00
100_R	122_N	0.592	1.00
98_T	135_K	0.591	1.00
253_T	256_H	0.590	1.00
134_E	137_Y	0.590	1.00
253_T	257_L	0.590	1.00
271_F	278_Q	0.587	1.00
51_L	163_L	0.585	1.00
186_I	194_I	0.584	1.00
258_L	264_G	0.583	1.00
57_P	62_V	0.582	1.00
184_S	207_I	0.577	1.00
21_V	47_L	0.569	1.00
264_G	271_F	0.569	1.00
274_E	282_T	0.568	1.00
26_L	34_F	0.566	1.00
91_F	146_K	0.564	1.00
243_Q	247_P	0.561	1.00
242_Q	245_T	0.561	1.00
232_P	237_T	0.561	1.00
112_V	117_R	0.559	1.00
181_D	206_K	0.558	1.00
98_T	137_Y	0.557	1.00
262_A	266_M	0.556	1.00
267_V	275_S	0.555	1.00
277_E	284_M	0.555	1.00
249_E	252_E	0.554	1.00
124_L	128_V	0.550	1.00
205_R	224_E	0.548	1.00
281_I	284_M	0.548	1.00
187_N	194_I	0.547	1.00
268_Q	273_G	0.546	1.00
104_M	107_L	0.544	1.00
53_G	64_V	0.541	1.00
33_I	196_L	0.540	1.00
107_L	156_A	0.540	1.00
218_K	222_E	0.536	1.00
205_R	225_V	0.535	1.00
241_V	244_V	0.534	1.00
271_F	281_I	0.533	1.00
280_L	285_I	0.531	1.00
2_I	51_L	0.530	1.00
203_V	207_I	0.529	1.00
48_I	52_N	0.529	1.00
2_I	64_V	0.528	1.00
4_L	47_L	0.528	1.00
272_V	277_E	0.527	1.00
33_I	209_N	0.526	1.00
107_L	111_G	0.525	1.00
150_G	153_R	0.523	1.00
263_S	268_Q	0.523	1.00
36_I	212_A	0.522	1.00
249_E	254_L	0.522	1.00
8_S	21_V	0.520	1.00
105_F	109_I	0.518	1.00
9_K	21_V	0.518	1.00
204_I	208_C	0.518	1.00
136_S	141_L	0.514	1.00
263_S	266_M	0.514	1.00
273_G	282_T	0.511	1.00
162_L	194_I	0.511	1.00
86_M	89_Q	0.511	1.00
46_S	55_E	0.508	1.00
173_P	177_D	0.506	1.00
2_I	161_V	0.506	1.00
113_K	120_R	0.505	1.00
274_E	279_P	0.504	1.00
106_P	109_I	0.504	1.00
261_T	267_V	0.502	1.00
118_I	121_A	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3tuiC	2	1	100	0.178	Contact Map
4yerA	2	0.8299	100	0.204	Contact Map
4ymuJ	2	0.7009	100	0.238	Contact Map
4u00A	1	0.7009	100	0.238	Contact Map
2oljA	2	0.7009	100	0.239	Contact Map
1vplA	2	0.695	100	0.241	Contact Map
4rvcA	4	0.7009	100	0.242	Contact Map
1b0uA	2	0.7185	100	0.242	Contact Map
4huqB	1	0.7977	100	0.244	Contact Map
2it1A	1	0.8065	100	0.246	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0121 seconds.