METQ - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

METQ - Methionine-binding lipoprotein MetQ

UniProt:	O32167	Sequences: MKKLFLGALLLVFAGVMAACGSNNGAESGKKEIVVAATKTPHAEILKEAEPLLKEKGYTLKVKVLSDYKMYNKALADKEVDANYFQHIPYLEQEMKENTDYKLVNAGAVHLEPFGIYSKTYKSLKDLPDGATIILTNNVAEQGRMLAMLENAGLITLDSKVETVDATLKDIKKNPKNLEFKKVAPELTAKAYENKEGDAVFINVNYAIQNKLNPKKDAIEVESTKNNPYANIIAVRKGEEDSAKIKALMEVLHSKKIKDFIEKKYDGAVLPVSE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	274 (258)
Sequences:	3629 (2508)
Seq/√Len:	156.1

ECOLI - NLPA METQ
BACSU - METQ YHCJ

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
156_T	173_K	3.595	1.00
255_K	259_D	3.351	1.00
34_V	63_K	3.181	1.00
132_T	181_K	3.166	1.00
102_K	237_K	3.095	1.00
134_I	197_G	3.027	1.00
236_R	239_E	3.004	1.00
131_A	198_D	2.943	1.00
36_A	80_V	2.924	1.00
259_D	263_K	2.883	1.00
88_I	92_E	2.839	1.00
52_L	256_K	2.802	1.00
32_E	59_T	2.546	1.00
93_Q	97_E	2.532	1.00
129_D	177_N	2.520	1.00
119_K	193_E	2.497	1.00
132_T	179_E	2.430	1.00
106_A	245_I	2.338	1.00
121_Y	128_P	2.327	1.00
107_G	249_M	2.327	1.00
54_K	59_T	2.160	1.00
239_E	242_S	2.155	1.00
32_E	61_K	2.145	1.00
122_K	126_D	2.112	1.00
104_V	237_K	2.088	1.00
48_E	257_I	2.088	1.00
135_L	142_Q	2.065	1.00
128_P	131_A	2.060	1.00
94_E	101_Y	2.038	1.00
34_V	61_K	2.031	1.00
136_T	145_M	2.030	1.00
133_I	199_A	2.017	1.00
76_A	102_K	1.999	1.00
168_L	182_K	1.996	1.00
147_A	150_E	1.983	1.00
56_K	247_A	1.980	1.00
95_M	101_Y	1.929	1.00
259_D	262_E	1.825	1.00
133_I	178_L	1.801	1.00
116_I	199_A	1.789	1.00
103_L	234_A	1.776	1.00
82_A	235_V	1.752	1.00
47_K	50_E	1.752	1.00
152_A	220_E	1.703	1.00
212_L	217_D	1.679	1.00
154_L	178_L	1.666	1.00
127_L	199_A	1.665	1.00
151_N	223_S	1.607	1.00
243_A	247_A	1.603	1.00
78_K	236_R	1.592	1.00
73_K	77_D	1.590	1.00
121_Y	198_D	1.571	1.00
255_K	258_K	1.558	1.00
237_K	240_E	1.531	1.00
213_N	217_D	1.528	1.00
88_I	105_N	1.527	1.00
108_A	230_A	1.524	1.00
58_Y	247_A	1.512	1.00
82_A	248_L	1.496	1.00
115_G	221_V	1.417	1.00
135_L	180_F	1.413	1.00
44_E	264_K	1.407	1.00
246_K	250_E	1.406	1.00
156_T	172_K	1.405	1.00
115_G	218_A	1.404	1.00
48_E	51_P	1.402	1.00
158_D	172_K	1.381	1.00
171_I	180_F	1.363	1.00
69_K	90_Y	1.358	1.00
249_M	253_H	1.347	1.00
158_D	170_D	1.342	1.00
127_L	131_A	1.331	1.00
31_K	244_K	1.330	1.00
48_E	52_L	1.328	1.00
73_K	94_E	1.324	1.00
104_V	240_E	1.310	1.00
52_L	257_I	1.304	1.00
52_L	55_E	1.301	1.00
52_L	251_V	1.296	1.00
129_D	176_K	1.295	1.00
76_A	101_Y	1.286	1.00
161_V	166_A	1.286	1.00
56_K	250_E	1.286	1.00
233_I	249_M	1.272	1.00
242_S	245_I	1.270	1.00
134_I	191_A	1.264	1.00
260_F	264_K	1.257	1.00
88_I	232_I	1.238	1.00
241_D	246_K	1.230	1.00
43_A	64_V	1.227	1.00
123_S	126_D	1.215	1.00
73_K	98_N	1.203	1.00
124_L	220_E	1.200	1.00
138_N	141_E	1.195	1.00
47_K	62_V	1.190	1.00
75_L	80_V	1.171	1.00
33_I	244_K	1.155	1.00
44_E	265_Y	1.150	1.00
48_E	260_F	1.146	1.00
106_A	249_M	1.145	1.00
193_E	196_E	1.135	1.00
197_G	200_V	1.135	1.00
157_L	172_K	1.125	1.00
105_N	232_I	1.123	1.00
36_A	75_L	1.122	1.00
33_I	58_Y	1.112	1.00
58_Y	244_K	1.102	0.99
95_M	237_K	1.099	0.99
20_C	23_N	1.095	0.99
37_A	46_L	1.095	0.99
120_T	198_D	1.085	0.99
121_Y	131_A	1.082	0.99
124_L	127_L	1.078	0.99
235_V	239_E	1.077	0.99
116_I	201_F	1.069	0.99
92_E	96_K	1.069	0.99
150_E	156_T	1.058	0.99
78_K	238_G	1.057	0.99
95_M	102_K	1.054	0.99
42_H	110_H	1.053	0.99
88_I	108_A	1.046	0.99
188_T	200_V	1.044	0.99
70_M	73_K	1.033	0.99
143_G	166_A	1.027	0.99
183_V	191_A	1.020	0.99
84_Y	109_V	1.016	0.99
72_N	86_Q	1.003	0.99
235_V	238_G	0.990	0.99
82_A	245_I	0.989	0.99
223_S	226_N	0.988	0.99
95_M	103_L	0.985	0.99
13_F	16_V	0.984	0.99
36_A	65_L	0.981	0.99
75_L	236_R	0.970	0.99
50_E	54_K	0.965	0.99
35_V	46_L	0.963	0.99
37_A	43_A	0.961	0.99
12_V	15_G	0.954	0.99
93_Q	96_K	0.952	0.98
106_A	235_V	0.948	0.98
48_E	256_K	0.943	0.98
91_L	95_M	0.943	0.98
247_A	250_E	0.938	0.98
95_M	104_V	0.935	0.98
68_Y	185_P	0.930	0.98
91_L	232_I	0.925	0.98
150_E	154_L	0.925	0.98
158_D	161_V	0.925	0.98
16_V	19_A	0.924	0.98
44_E	47_K	0.923	0.98
34_V	81_D	0.919	0.98
83_N	86_Q	0.915	0.98
53_L	58_Y	0.908	0.98
65_L	74_A	0.907	0.98
174_N	178_L	0.905	0.98
114_F	201_F	0.904	0.98
199_A	219_I	0.902	0.98
142_Q	168_L	0.901	0.98
49_A	52_L	0.896	0.98
183_V	188_T	0.891	0.98
51_P	55_E	0.886	0.98
107_G	233_I	0.883	0.98
51_P	54_K	0.875	0.97
91_L	234_A	0.870	0.97
116_I	124_L	0.868	0.97
93_Q	140_A	0.866	0.97
67_D	70_M	0.865	0.97
73_K	76_A	0.862	0.97
105_N	108_A	0.862	0.97
84_Y	252_L	0.861	0.97
30_K	59_T	0.858	0.97
107_G	253_H	0.856	0.97
94_E	98_N	0.855	0.97
121_Y	199_A	0.854	0.97
112_E	205_N	0.853	0.97
238_G	242_S	0.845	0.97
33_I	248_L	0.835	0.97
247_A	251_V	0.834	0.97
213_N	266_D	0.828	0.96
84_Y	110_H	0.826	0.96
98_N	101_Y	0.819	0.96
214_P	218_A	0.818	0.96
189_A	210_N	0.813	0.96
42_H	112_E	0.810	0.96
52_L	254_S	0.806	0.96
53_L	251_V	0.802	0.96
118_S	121_Y	0.796	0.95
258_K	262_E	0.796	0.95
48_E	251_V	0.792	0.95
207_A	212_L	0.788	0.95
11_L	14_A	0.787	0.95
109_V	252_L	0.784	0.95
72_N	85_F	0.781	0.95
168_L	180_F	0.777	0.95
127_L	154_L	0.776	0.95
20_C	24_N	0.771	0.95
65_L	80_V	0.770	0.95
17_M	20_C	0.769	0.95
214_P	221_V	0.769	0.95
31_K	58_Y	0.769	0.95
14_A	18_A	0.766	0.94
12_V	16_V	0.763	0.94
34_V	75_L	0.763	0.94
50_E	59_T	0.761	0.94
46_L	84_Y	0.761	0.94
192_Y	200_V	0.760	0.94
224_T	227_N	0.759	0.94
187_L	191_A	0.757	0.94
213_N	218_A	0.757	0.94
72_N	83_N	0.751	0.94
94_E	103_L	0.749	0.94
134_I	188_T	0.746	0.94
203_N	231_N	0.744	0.94
11_L	15_G	0.744	0.94
49_A	251_V	0.742	0.93
262_E	271_P	0.741	0.93
109_V	253_H	0.741	0.93
190_K	193_E	0.737	0.93
218_A	221_V	0.736	0.93
105_N	249_M	0.730	0.93
142_Q	182_K	0.728	0.93
162_E	166_A	0.727	0.93
167_T	170_D	0.726	0.93
191_A	196_E	0.726	0.93
214_P	217_D	0.724	0.93
87_H	140_A	0.724	0.93
185_P	203_N	0.723	0.93
159_S	162_E	0.723	0.93
138_N	185_P	0.720	0.92
30_K	244_K	0.713	0.92
75_L	239_E	0.712	0.92
143_G	147_A	0.710	0.92
42_H	84_Y	0.709	0.92
130_G	177_N	0.705	0.92
46_L	60_L	0.703	0.91
145_M	201_F	0.703	0.91
56_K	251_V	0.702	0.91
68_Y	71_Y	0.693	0.91
109_V	249_M	0.692	0.91
105_N	234_A	0.691	0.91
112_E	269_V	0.689	0.91
174_N	177_N	0.689	0.91
73_K	101_Y	0.687	0.91
85_F	90_Y	0.686	0.90
187_L	190_K	0.683	0.90
148_M	152_A	0.683	0.90
127_L	198_D	0.683	0.90
151_N	226_N	0.680	0.90
84_Y	112_E	0.679	0.90
168_L	172_K	0.676	0.90
68_Y	75_L	0.670	0.89
43_A	47_K	0.669	0.89
223_S	227_N	0.664	0.89
205_N	209_Q	0.663	0.89
63_K	75_L	0.661	0.89
215_K	218_A	0.659	0.89
233_I	252_L	0.658	0.89
204_V	268_A	0.658	0.89
172_K	175_P	0.658	0.89
255_K	262_E	0.654	0.88
53_L	60_L	0.652	0.88
11_L	16_V	0.644	0.87
147_A	151_N	0.643	0.87
68_Y	203_N	0.643	0.87
134_I	183_V	0.642	0.87
155_I	180_F	0.642	0.87
122_K	217_D	0.641	0.87
50_E	62_V	0.641	0.87
192_Y	197_G	0.640	0.87
186_E	206_Y	0.638	0.87
106_A	234_A	0.637	0.87
52_L	56_K	0.636	0.87
40_T	44_E	0.634	0.87
39_K	64_V	0.634	0.87
127_L	133_I	0.633	0.87
154_L	199_A	0.632	0.87
10_L	14_A	0.628	0.86
235_V	242_S	0.624	0.86
162_E	165_D	0.623	0.86
116_I	220_E	0.623	0.86
121_Y	127_L	0.622	0.86
89_P	228_P	0.621	0.86
27_E	30_K	0.620	0.85
28_S	31_K	0.618	0.85
68_Y	231_N	0.618	0.85
118_S	126_D	0.615	0.85
192_Y	212_L	0.615	0.85
6_L	16_V	0.613	0.85
87_H	138_N	0.609	0.84
146_L	155_I	0.609	0.84
147_A	166_A	0.606	0.84
40_T	265_Y	0.606	0.84
260_F	263_K	0.605	0.84
104_V	235_V	0.604	0.84
150_E	162_E	0.602	0.84
42_H	46_L	0.602	0.84
46_L	252_L	0.601	0.84
87_H	91_L	0.597	0.83
263_K	266_D	0.595	0.83
242_S	246_K	0.587	0.82
36_A	74_A	0.585	0.82
136_T	185_P	0.584	0.82
71_Y	75_L	0.581	0.82
141_E	145_M	0.575	0.81
258_K	271_P	0.572	0.81
90_Y	94_E	0.571	0.80
168_L	179_E	0.570	0.80
76_A	94_E	0.566	0.80
91_L	103_L	0.565	0.80
125_K	152_A	0.564	0.80
181_K	197_G	0.564	0.80
137_N	184_A	0.563	0.80
87_H	141_E	0.559	0.79
192_Y	202_I	0.558	0.79
109_V	112_E	0.557	0.79
250_E	253_H	0.554	0.78
260_F	265_Y	0.553	0.78
184_A	189_A	0.552	0.78
116_I	127_L	0.552	0.78
68_Y	138_N	0.551	0.78
18_A	21_G	0.551	0.78
185_P	189_A	0.549	0.78
136_T	201_F	0.548	0.78
239_E	245_I	0.548	0.78
23_N	29_G	0.548	0.78
146_L	157_L	0.547	0.78
147_A	164_V	0.545	0.77
47_K	64_V	0.545	0.77
35_V	61_K	0.545	0.77
150_E	159_S	0.542	0.77
149_L	201_F	0.541	0.77
92_E	95_M	0.541	0.77
142_Q	185_P	0.540	0.77
114_F	204_V	0.539	0.77
235_V	240_E	0.538	0.76
136_T	141_E	0.538	0.76
178_L	199_A	0.538	0.76
96_K	165_D	0.535	0.76
150_E	160_K	0.534	0.76
121_Y	124_L	0.534	0.76
87_H	232_I	0.534	0.76
138_N	145_M	0.533	0.76
112_E	204_V	0.532	0.76
124_L	219_I	0.530	0.75
83_N	90_Y	0.527	0.75
113_P	203_N	0.526	0.75
131_A	174_N	0.526	0.75
89_P	227_N	0.525	0.75
94_E	100_D	0.525	0.75
97_E	165_D	0.525	0.75
46_L	62_V	0.523	0.74
189_A	206_Y	0.523	0.74
153_G	156_T	0.523	0.74
90_Y	209_Q	0.523	0.74
31_K	59_T	0.521	0.74
205_N	208_I	0.521	0.74
112_E	231_N	0.520	0.74
7_G	14_A	0.517	0.74
69_K	98_N	0.517	0.74
50_E	61_K	0.516	0.73
19_A	22_S	0.516	0.73
130_G	179_E	0.515	0.73
67_D	71_Y	0.515	0.73
60_L	248_L	0.515	0.73
69_K	73_K	0.514	0.73
33_I	60_L	0.514	0.73
13_F	17_M	0.513	0.73
150_E	172_K	0.512	0.73
114_F	203_N	0.512	0.73
45_I	260_F	0.511	0.73
33_I	245_I	0.511	0.73
6_L	9_L	0.510	0.73
111_L	227_N	0.509	0.72
106_A	240_E	0.509	0.72
84_Y	233_I	0.507	0.72
49_A	257_I	0.507	0.72
174_N	180_F	0.506	0.72
140_A	145_M	0.505	0.72
122_K	125_K	0.504	0.72
122_K	156_T	0.504	0.72
31_K	247_A	0.503	0.72
220_E	223_S	0.503	0.72
7_G	10_L	0.503	0.72
121_Y	178_L	0.502	0.71
161_V	170_D	0.501	0.71
113_P	228_P	0.501	0.71
189_A	202_I	0.500	0.71

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4qhqA	1	0.865	100	0.404	Contact Map
3ir1A	3	0.8686	100	0.466	Contact Map
4ntlA	1	0.8759	100	0.478	Contact Map
4oteA	4	0.8759	100	0.487	Contact Map
3up9A	1	0.8613	100	0.488	Contact Map
1xs5A	1	0.8723	100	0.507	Contact Map
4k3fA	1	0.8759	100	0.51	Contact Map
3tqwA	1	0.854	100	0.514	Contact Map
3gxaA	3	0.8686	100	0.516	Contact Map
4q5tA	1	0.8905	100	0.535	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0082 seconds.