GREMLIN Database
YURN - Probable ABC transporter permease protein YurN
UniProt: O32155 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 292 (251)
Sequences: 69309 (44333)
Seq/√Len: 2798.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
200_Q204_H3.9031.00
67_T71_L3.1581.00
192_R201_Q2.9761.00
177_I181_Q2.9741.00
64_Q67_T2.5801.00
65_A250_F2.5771.00
93_D188_Y2.5371.00
179_S213_M2.4951.00
75_I161_I2.4791.00
34_S53_Y2.4621.00
191_A201_Q2.4601.00
188_Y206_T2.4561.00
79_C165_Q2.4511.00
245_E253_K2.4261.00
197_G200_Q2.3921.00
63_Y67_T2.2981.00
51_K54_V2.2881.00
77_I218_V2.2641.00
198_K201_Q2.2631.00
54_V58_H2.2591.00
176_Y214_S2.1941.00
51_K55_E2.1611.00
260_M263_Y2.1021.00
199_I203_F2.1001.00
196_A200_Q2.0371.00
200_Q203_F1.9851.00
85_L202_F1.9821.00
172_I217_A1.9411.00
96_V99_W1.9271.00
180_I210_T1.8941.00
187_L209_Q1.8891.00
71_L157_M1.8821.00
92_E181_Q1.8581.00
191_A196_A1.8301.00
32_F36_F1.8211.00
104_R177_I1.8161.00
85_L210_T1.7871.00
28_F32_F1.7471.00
81_V218_V1.7431.00
280_L284_K1.7041.00
64_Q68_N1.6901.00
192_R198_K1.6831.00
188_Y201_Q1.6681.00
84_G172_I1.6541.00
73_A222_L1.6531.00
76_S225_A1.6461.00
55_E263_Y1.6081.00
71_L75_I1.5991.00
85_L176_Y1.5871.00
91_L173_A1.5771.00
87_L173_A1.5701.00
188_Y192_R1.5571.00
157_M244_S1.5541.00
250_F254_S1.5181.00
96_V100_S1.5091.00
10_Y14_V1.4711.00
25_I29_E1.4451.00
185_D188_Y1.4341.00
55_E58_H1.4321.00
13_L17_L1.4271.00
31_V269_T1.4221.00
99_W102_F1.4171.00
172_I221_T1.4091.00
216_V220_M1.3781.00
50_L54_V1.3781.00
49_G52_N1.3761.00
238_G243_A1.3711.00
72_Y246_V1.3651.00
231_E235_L1.3581.00
180_I206_T1.3501.00
88_A176_Y1.3431.00
92_E177_I1.3381.00
95_L100_S1.3241.00
80_Q221_T1.3211.00
207_V214_S1.3201.00
10_Y13_L1.3151.00
61_V64_Q1.3051.00
176_Y217_A1.2981.00
29_E33_L1.2871.00
82_F86_I1.2851.00
254_S258_K1.2841.00
239_G243_A1.2751.00
185_D189_E1.2701.00
126_Y159_S1.2581.00
229_F233_Y1.2511.00
236_T244_S1.2401.00
93_D185_D1.2321.00
191_A205_I1.2181.00
186_E189_E1.2181.00
229_F252_Y1.2151.00
163_V235_L1.2131.00
69_N247_L1.2111.00
89_A180_I1.2061.00
254_S260_M1.1971.00
85_L214_S1.1941.00
102_F105_T1.1751.00
37_Q40_S1.1741.00
78_V82_F1.1691.00
156_A244_S1.1691.00
183_I209_Q1.1661.00
245_E250_F1.1651.00
75_I78_V1.1551.00
40_S47_F1.1331.00
211_K215_F1.1251.00
81_V214_S1.1181.00
197_G201_Q1.1111.00
68_N71_L1.1101.00
30_N269_T1.0801.00
253_K257_T1.0701.00
161_I165_Q1.0571.00
176_Y213_M1.0531.00
124_F128_P1.0491.00
102_F106_V1.0411.00
188_Y198_K1.0391.00
246_V249_T1.0361.00
175_L217_A1.0311.00
79_C161_I1.0271.00
160_V232_P1.0251.00
169_V173_A1.0221.00
75_I79_C1.0141.00
209_Q212_E1.0061.00
245_E249_T1.0061.00
57_F63_Y1.0031.00
76_S80_Q1.0031.00
250_F267_I1.0021.00
89_A202_F1.0011.00
92_E180_I0.9991.00
281_M285_F0.9951.00
157_M161_I0.9911.00
89_A198_K0.9891.00
76_S164_S0.9841.00
228_V231_E0.9821.00
232_P246_V0.9801.00
86_I90_V0.9721.00
9_P13_L0.9691.00
29_E32_F0.9691.00
53_Y269_T0.9581.00
14_V17_L0.9571.00
158_L162_F0.9551.00
100_S181_Q0.9511.00
66_L247_L0.9481.00
255_A264_A0.9451.00
196_A201_Q0.9401.00
233_Y249_T0.9381.00
70_V74_V0.9351.00
14_V18_V0.9321.00
78_V218_V0.9271.00
201_Q204_H0.9271.00
71_L158_L0.9261.00
228_V232_P0.9201.00
76_S161_I0.9171.00
33_L36_F0.9171.00
68_N157_M0.9161.00
55_E59_D0.9011.00
38_W42_S0.9001.00
88_A92_E0.8981.00
122_F235_L0.8901.00
20_L24_Y0.8901.00
238_G244_S0.8871.00
72_Y157_M0.8751.00
122_F163_V0.8741.00
62_F267_I0.8721.00
74_V78_V0.8691.00
164_S225_A0.8661.00
36_F40_S0.8661.00
90_V96_V0.8651.00
108_F174_M0.8601.00
142_L158_L0.8561.00
176_Y210_T0.8551.00
101_P104_R0.8531.00
71_L74_V0.8521.00
115_M167_Q0.8521.00
172_I176_Y0.8471.00
33_L265_S0.8471.00
250_F253_K0.8431.00
72_Y164_S0.8361.00
39_S42_S0.8351.00
66_L70_V0.8341.00
179_S210_T0.8331.00
211_K214_S0.8321.00
163_V231_E0.8311.00
79_C82_F0.8281.00
98_K101_P0.8261.00
13_L16_A0.8251.00
88_A173_A0.8251.00
210_T213_M0.8221.00
80_Q84_G0.8211.00
56_L270_V0.8201.00
91_L104_R0.8111.00
84_G173_A0.8111.00
35_L48_I0.8111.00
281_M284_K0.8071.00
201_Q206_T0.8031.00
123_D127_N0.7981.00
203_F207_V0.7971.00
202_F207_V0.7961.00
196_A204_H0.7941.00
221_T225_A0.7931.00
254_S267_I0.7871.00
88_A180_I0.7851.00
277_A281_M0.7841.00
254_S263_Y0.7831.00
275_T279_S0.7801.00
52_N262_G0.7771.00
95_L99_W0.7771.00
141_G144_Q0.7701.00
158_L161_I0.7691.00
11_L15_P0.7661.00
34_S38_W0.7641.00
59_D63_Y0.7631.00
119_A230_N0.7621.00
30_N265_S0.7621.00
12_F16_A0.7591.00
33_L37_Q0.7571.00
80_Q168_S0.7541.00
67_T70_V0.7541.00
239_G245_E0.7531.00
263_Y267_I0.7521.00
198_K202_F0.7471.00
48_I51_K0.7431.00
282_Q285_F0.7381.00
11_L14_V0.7371.00
75_I165_Q0.7351.00
187_L205_I0.7331.00
119_A234_I0.7281.00
81_V176_Y0.7251.00
252_Y256_F0.7241.00
202_F206_T0.7231.00
65_A68_N0.7171.00
65_A247_L0.7141.00
77_I222_L0.7121.00
84_G176_Y0.7111.00
52_N55_E0.7101.00
80_Q172_I0.7091.00
60_P64_Q0.7081.00
50_L53_Y0.7081.00
25_I28_F0.7061.00
183_I210_T0.7051.00
108_F111_V0.7051.00
36_F45_K0.7051.00
118_I166_W0.7011.00
37_Q47_F0.7011.00
156_A159_S0.7011.00
265_S269_T0.7011.00
228_V246_V0.6951.00
55_E260_M0.6941.00
247_L271_V0.6941.00
249_T253_K0.6901.00
190_A194_D0.6861.00
115_M230_N0.6851.00
95_L98_K0.6841.00
80_Q225_A0.6811.00
40_S46_T0.6811.00
30_N268_A0.6791.00
168_S221_T0.6791.00
251_L267_I0.6761.00
214_S217_A0.6691.00
211_K285_F0.6681.00
124_F127_N0.6681.00
73_A77_I0.6661.00
185_D192_R0.6631.00
248_S271_V0.6621.00
265_S268_A0.6621.00
35_L49_G0.6611.00
54_V57_F0.6611.00
37_Q46_T0.6611.00
91_L103_F0.6611.00
168_S224_G0.6601.00
94_K100_S0.6591.00
26_P30_N0.6581.00
176_Y180_I0.6581.00
91_L177_I0.6571.00
206_T209_Q0.6561.00
159_S163_V0.6551.00
190_A193_L0.6521.00
239_G244_S0.6441.00
40_S43_P0.6431.00
213_M217_A0.6411.00
63_Y66_L0.6371.00
87_L169_V0.6351.00
83_G165_Q0.6321.00
160_V236_T0.6291.00
19_F23_V0.6261.00
77_I81_V0.6241.00
214_S218_V0.6231.00
87_L107_F0.6191.00
56_L263_Y0.6181.00
99_W103_F0.6171.00
271_V275_T0.6141.00
33_L38_W0.6131.00
69_N226_F0.6111.00
47_F51_K0.6101.00
72_Y161_I0.6081.00
107_F170_G0.6051.00
69_N248_S0.6041.00
236_T245_E0.6021.00
230_N234_I0.5971.00
262_G265_S0.5961.00
159_S235_L0.5951.00
49_G53_Y0.5951.00
20_L23_V0.5921.00
61_V250_F0.5921.00
68_N244_S0.5921.00
15_P18_V0.5911.00
90_V94_K0.5891.00
47_F50_L0.5891.00
72_Y160_V0.5881.00
276_L280_L0.5881.00
104_R174_M0.5881.00
73_A225_A0.5871.00
80_Q165_Q0.5871.00
127_N143_D0.5861.00
232_P249_T0.5831.00
263_Y266_A0.5821.00
105_T109_L0.5801.00
140_I143_D0.5791.00
116_T234_I0.5791.00
98_K102_F0.5771.00
39_S43_P0.5761.00
261_M265_S0.5761.00
56_L267_I0.5761.00
34_S269_T0.5721.00
72_Y76_S0.5711.00
175_L213_M0.5701.00
111_V170_G0.5701.00
101_P105_T0.5681.00
24_Y28_F0.5681.00
60_P63_Y0.5681.00
53_Y266_A0.5671.00
61_V245_E0.5651.00
203_F206_T0.5641.00
36_F47_F0.5631.00
111_V171_Y0.5631.00
89_A206_T0.5601.00
12_F15_P0.5591.00
223_T227_T0.5591.00
274_I277_A0.5561.00
224_G227_T0.5551.00
249_T252_Y0.5501.00
261_M264_A0.5501.00
279_S283_M0.5501.00
164_S228_V0.5481.00
81_V85_L0.5471.00
122_F125_I0.5461.00
34_S266_A0.5461.00
215_F218_V0.5451.00
17_L21_L0.5431.00
218_V221_T0.5421.00
83_G169_V0.5421.00
57_F60_P0.5411.00
38_W45_K0.5401.00
201_Q205_I0.5391.00
110_P170_G0.5371.00
280_L283_M0.5321.00
106_V110_P0.5301.00
77_I225_A0.5291.00
230_N233_Y0.5291.00
76_S165_Q0.5271.00
36_F46_T0.5271.00
87_L90_V0.5271.00
123_D143_D0.5261.00
73_A226_F0.5261.00
167_Q231_E0.5251.00
88_A177_I0.5241.00
160_V164_S0.5231.00
119_A123_D0.5181.00
21_L25_I0.5161.00
225_A228_V0.5161.00
68_N246_V0.5141.00
81_V86_I0.5121.00
197_G203_F0.5121.00
183_I188_Y0.5071.00
26_P31_V0.5041.00
104_R181_Q0.5041.00
277_A280_L0.5031.00
17_L20_L0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4tquM 1 0.9486 100 0.288 Contact Map
2onkC 2 0.8459 100 0.315 Contact Map
3d31C 2 0.8493 100 0.338 Contact Map
3rlfF 1 0.9349 100 0.34 Contact Map
3rlfG 1 0.9075 100 0.373 Contact Map
4tquN 1 0.8836 100 0.38 Contact Map
4ymuD 2 0.7363 99.9 0.503 Contact Map
3tuiA 2 0.7192 99.9 0.519 Contact Map
2m20A 2 0.1233 17.5 0.944 Contact Map
2mfrA 1 0.161 16.5 0.945 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0108 seconds.