GREMLIN Database
YURJ - Uncharacterized ABC transporter ATP-binding protein YurJ
UniProt: O32151 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 367 (312)
Sequences: 20258 (14722)
Seq/√Len: 833.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
216_A220_D4.2931.00
33_V201_G3.8711.00
59_N66_R3.8291.00
8_H21_D3.7471.00
30_E203_R3.6531.00
5_T25_D3.5841.00
7_E59_N3.4491.00
119_R124_E3.4031.00
17_L20_K3.3601.00
111_A115_H2.9781.00
32_L205_V2.6781.00
106_A109_E2.6471.00
217_K220_D2.6431.00
20_K211_E2.5941.00
213_Q227_N2.5851.00
10_K57_E2.5471.00
93_F97_A2.5231.00
6_F9_V2.4751.00
10_K17_L2.4681.00
126_L129_R2.4521.00
7_E61_L2.4351.00
5_T61_L2.4061.00
27_K30_E2.3911.00
12_S17_L2.3631.00
93_F128_K2.3001.00
113_R151_E2.2961.00
11_K48_M2.2601.00
8_H23_D2.2251.00
93_F115_H2.2181.00
10_K21_D2.1731.00
76_D153_K2.1651.00
93_F111_A2.1241.00
122_E171_T2.1121.00
198_M219_H2.0581.00
4_L154_V2.0551.00
9_V55_I1.9811.00
228_L283_I1.9811.00
118_A127_L1.9581.00
63_D153_K1.9531.00
11_K56_S1.9521.00
61_L66_R1.9451.00
48_M55_I1.8751.00
205_V215_V1.8751.00
19_V48_M1.8631.00
46_L190_V1.8311.00
49_V188_I1.7941.00
208_N213_Q1.7771.00
112_E116_A1.7521.00
108_Q112_E1.7501.00
109_E112_E1.7471.00
205_V212_I1.7351.00
113_R116_A1.7231.00
11_K53_E1.7181.00
93_F114_V1.5841.00
47_R53_E1.5671.00
12_S56_S1.5631.00
62_I67_V1.5461.00
97_A114_V1.5421.00
109_E113_R1.5251.00
228_L241_F1.5231.00
66_R69_D1.5141.00
67_V70_L1.5041.00
157_M187_I1.5041.00
121_L145_G1.4991.00
115_H119_R1.4981.00
90_M98_F1.4811.00
46_L156_L1.4731.00
26_V32_L1.4611.00
219_H223_H1.4591.00
6_F24_L1.4511.00
117_A149_V1.4371.00
251_G255_F1.4371.00
105_M109_E1.4321.00
116_A119_R1.4311.00
32_L215_V1.4191.00
48_M60_L1.4071.00
241_F283_I1.4061.00
65_E70_L1.4031.00
6_F49_V1.3971.00
232_G241_F1.3941.00
65_E153_K1.3851.00
245_I281_Q1.3741.00
22_F45_T1.3721.00
89_H132_K1.3631.00
277_Y280_E1.3611.00
55_I60_L1.3301.00
105_M110_I1.3171.00
10_K20_K1.3171.00
47_R52_L1.3161.00
91_T94_D1.3151.00
59_N68_N1.2841.00
24_L205_V1.2791.00
228_L232_G1.2581.00
253_L256_T1.2451.00
91_T130_K1.2441.00
97_A110_I1.2351.00
6_F45_T1.2271.00
257_N260_I1.2091.00
301_F304_V1.1951.00
180_H185_A1.1851.00
180_H187_I1.1841.00
32_L203_R1.1841.00
19_V22_F1.1831.00
7_E23_D1.1831.00
94_D101_K1.1731.00
220_D224_Y1.1701.00
177_S200_M1.1611.00
107_K111_A1.1581.00
110_I114_V1.1571.00
115_H127_L1.1561.00
87_Y90_M1.1541.00
70_L74_E1.1461.00
116_A120_I1.1441.00
252_E255_F1.1431.00
94_D97_A1.1361.00
12_S18_T1.1341.00
101_K107_K1.1141.00
92_V134_L1.1101.00
251_G254_F1.1041.00
78_A147_S1.0951.00
19_V45_T1.0901.00
276_G280_E1.0891.00
258_S261_R1.0881.00
116_A151_E1.0871.00
243_K283_I1.0861.00
294_M297_N1.0821.00
248_Q251_G1.0791.00
28_D63_D1.0761.00
262_L265_P1.0721.00
50_A156_L1.0721.00
212_I215_V1.0711.00
265_P269_A1.0631.00
97_A101_K1.0611.00
55_I68_N1.0571.00
12_S57_E1.0511.00
33_V197_A1.0481.00
27_K203_R1.0441.00
243_K281_Q1.0431.00
252_E256_T1.0411.00
251_G256_T1.0381.00
203_R215_V1.0371.00
107_K110_I1.0331.00
45_T207_M1.0271.00
9_V48_M1.0231.00
237_P285_G1.0191.00
177_S181_Q1.0171.00
314_N319_L1.0041.00
99_G150_R1.0021.00
206_V221_I1.0011.00
60_L67_V0.9991.00
256_T259_S0.9981.00
95_N146_R0.9971.00
129_R133_A0.9941.00
12_S15_S0.9901.00
130_K133_A0.9861.00
61_L64_G0.9831.00
264_I268_K0.9711.00
78_A152_P0.9691.00
255_F258_S0.9661.00
117_A148_I0.9641.00
115_H124_E0.9621.00
265_P268_K0.9561.00
244_G282_M0.9521.00
177_S199_T0.9461.00
208_N229_F0.9451.00
26_V186_T0.9451.00
8_H57_E0.9411.00
86_L131_P0.9411.00
269_A273_K0.9401.00
286_V291_I0.9371.00
276_G279_G0.9341.00
71_P74_E0.9311.00
30_E202_D0.9261.00
40_C207_M0.9251.00
24_L215_V0.9241.00
13_Y18_T0.9201.00
289_E293_Q0.9111.00
263_H266_E0.9071.00
31_L200_M0.9061.00
35_V206_V0.9051.00
191_T197_A0.9001.00
6_F60_L0.8991.00
289_E292_T0.8991.00
254_F257_N0.8951.00
93_F127_L0.8911.00
117_A120_I0.8891.00
98_F102_L0.8881.00
255_F259_S0.8881.00
87_Y99_G0.8871.00
96_M149_V0.8871.00
261_R265_P0.8861.00
96_M145_G0.8831.00
103_R150_R0.8811.00
31_L180_H0.8811.00
206_V230_V0.8781.00
309_V312_N0.8721.00
266_E269_A0.8681.00
293_Q296_G0.8671.00
5_T64_G0.8671.00
267_E271_R0.8661.00
276_G282_M0.8631.00
189_Y201_G0.8621.00
161_L189_Y0.8581.00
96_M118_A0.8541.00
261_R264_I0.8441.00
259_S262_L0.8381.00
161_L176_I0.8371.00
151_E185_A0.8371.00
34_L205_V0.8331.00
90_M94_D0.8321.00
29_K186_T0.8321.00
222_Y225_P0.8301.00
48_M56_S0.8301.00
273_K276_G0.8291.00
240_N243_K0.8251.00
29_K184_E0.8231.00
254_F258_S0.8221.00
256_T260_I0.8211.00
125_H129_R0.8181.00
105_M113_R0.8151.00
240_N244_G0.8091.00
223_H314_N0.8081.00
179_L185_A0.8061.00
286_V289_E0.8061.00
31_L187_I0.8041.00
303_S306_Q0.7981.00
169_R193_D0.7981.00
95_N131_P0.7981.00
257_N261_R0.7981.00
78_A150_R0.7961.00
170_V174_T0.7951.00
301_F309_V0.7941.00
152_P155_F0.7901.00
302_D308_N0.7891.00
155_F185_A0.7861.00
28_D153_K0.7851.00
48_M53_E0.7831.00
122_E125_H0.7821.00
311_V314_N0.7791.00
178_K311_V0.7791.00
219_H314_N0.7791.00
34_L45_T0.7761.00
271_R275_K0.7721.00
37_P40_C0.7721.00
258_S262_L0.7701.00
111_A114_V0.7681.00
174_T311_V0.7671.00
11_K44_T0.7671.00
43_S47_R0.7641.00
292_T295_T0.7641.00
32_L188_I0.7591.00
197_A201_G0.7591.00
248_Q255_F0.7581.00
144_L157_M0.7541.00
175_E178_K0.7481.00
9_V60_L0.7471.00
176_I187_I0.7461.00
261_R266_E0.7451.00
96_M99_G0.7441.00
21_D57_E0.7431.00
256_T261_R0.7431.00
262_L266_E0.7431.00
247_E256_T0.7401.00
301_F308_N0.7401.00
77_I154_V0.7401.00
131_P142_V0.7391.00
208_N211_E0.7371.00
99_G146_R0.7371.00
7_E25_D0.7351.00
166_A170_V0.7351.00
195_T199_T0.7291.00
288_P292_T0.7281.00
84_Y163_N0.7261.00
203_R214_Q0.7261.00
222_Y289_E0.7221.00
315_L320_I0.7211.00
190_V194_Q0.7211.00
271_R274_E0.7151.00
124_E127_L0.7151.00
113_R117_A0.7101.00
260_I264_I0.7091.00
153_K185_A0.7081.00
275_K279_G0.7061.00
253_L257_N0.6991.00
195_T315_L0.6971.00
157_M189_Y0.6961.00
62_I77_I0.6941.00
272_L276_G0.6911.00
159_E192_H0.6901.00
66_R75_R0.6891.00
290_H293_Q0.6881.00
40_C45_T0.6851.00
90_M95_N0.6841.00
259_S264_I0.6831.00
101_K110_I0.6821.00
249_Q254_F0.6821.00
80_V147_S0.6811.00
308_N311_V0.6801.00
304_V308_N0.6801.00
190_V193_D0.6781.00
206_V225_P0.6771.00
207_M212_I0.6771.00
250_H253_L0.6761.00
260_I265_P0.6761.00
247_E250_H0.6751.00
288_P291_I0.6701.00
282_M286_V0.6691.00
279_G283_I0.6691.00
118_A123_I0.6691.00
50_A79_M0.6691.00
167_K232_G0.6661.00
303_S307_A0.6641.00
218_P222_Y0.6641.00
253_L258_S0.6581.00
307_A310_E0.6561.00
14_H17_L0.6561.00
255_F260_I0.6551.00
92_V142_V0.6541.00
287_R291_I0.6531.00
118_A121_L0.6521.00
286_V292_T0.6511.00
269_A276_G0.6471.00
117_A121_L0.6461.00
13_Y53_E0.6451.00
220_D223_H0.6451.00
106_A110_I0.6441.00
284_A287_R0.6421.00
291_I294_M0.6401.00
91_T128_K0.6381.00
260_I263_H0.6371.00
114_V117_A0.6361.00
229_F232_G0.6361.00
166_A173_R0.6331.00
283_I287_R0.6321.00
155_F187_I0.6301.00
268_K271_R0.6291.00
287_R290_H0.6261.00
315_L318_E0.6241.00
254_F259_S0.6231.00
279_G282_M0.6231.00
249_Q252_E0.6221.00
108_Q111_A0.6211.00
276_G290_H0.6201.00
246_I249_Q0.6191.00
123_I126_L0.6191.00
281_Q285_G0.6171.00
304_V307_A0.6151.00
174_T178_K0.6151.00
264_I267_E0.6121.00
262_L268_K0.6121.00
170_V195_T0.6121.00
162_S166_A0.6111.00
86_L95_N0.6111.00
117_A145_G0.6091.00
293_Q297_N0.6091.00
223_H226_A0.6081.00
302_D306_Q0.6081.00
76_D150_R0.6081.00
275_K278_A0.6021.00
110_I113_R0.6011.00
219_H319_L0.5981.00
306_Q309_V0.5981.00
88_P132_K0.5971.00
93_F96_M0.5941.00
87_Y95_N0.5941.00
141_R164_L0.5921.00
172_M175_E0.5891.00
34_L207_M0.5891.00
263_H269_A0.5871.00
268_K272_L0.5851.00
82_Q163_N0.5851.00
154_V186_T0.5841.00
112_E115_H0.5821.00
239_M242_L0.5821.00
312_N316_G0.5821.00
270_K273_K0.5821.00
12_S20_K0.5811.00
317_S320_I0.5811.00
244_G284_A0.5801.00
247_E252_E0.5801.00
221_I225_P0.5791.00
11_K19_V0.5791.00
223_H227_N0.5781.00
177_S314_N0.5751.00
274_E278_A0.5741.00
93_F110_I0.5731.00
229_F233_F0.5731.00
257_N262_L0.5711.00
230_V233_F0.5691.00
78_A187_I0.5691.00
156_L188_I0.5681.00
125_H138_Q0.5661.00
171_T175_E0.5661.00
49_V156_L0.5651.00
82_Q136_G0.5651.00
274_E277_Y0.5601.00
270_K274_E0.5601.00
216_A221_I0.5541.00
173_R199_T0.5491.00
254_F261_R0.5471.00
83_N139_R0.5471.00
24_L212_I0.5471.00
249_Q253_L0.5451.00
249_Q255_F0.5431.00
307_A311_V0.5431.00
280_E283_I0.5401.00
240_N245_I0.5401.00
54_S69_D0.5391.00
34_L188_I0.5381.00
118_A124_E0.5381.00
292_T296_G0.5371.00
273_K277_Y0.5371.00
308_N312_N0.5361.00
22_F212_I0.5361.00
179_L187_I0.5341.00
262_L267_E0.5341.00
80_V140_Q0.5331.00
237_P241_F0.5321.00
302_D312_N0.5311.00
177_S202_D0.5311.00
178_K310_E0.5311.00
98_F101_K0.5311.00
76_D103_R0.5301.00
250_H256_T0.5301.00
163_N173_R0.5281.00
30_E215_V0.5281.00
91_T95_N0.5271.00
230_V234_I0.5271.00
242_L246_I0.5271.00
245_I249_Q0.5261.00
269_A275_K0.5251.00
31_L189_Y0.5251.00
170_V236_S0.5241.00
231_A235_G0.5241.00
285_G288_P0.5241.00
267_E270_K0.5231.00
20_K209_E0.5231.00
272_L279_G0.5221.00
144_L200_M0.5221.00
38_S192_H0.5221.00
222_Y226_A0.5221.00
204_I218_P0.5211.00
248_Q252_E0.5191.00
291_I297_N0.5191.00
125_H209_E0.5181.00
292_T297_N0.5181.00
169_R196_E0.5151.00
17_L21_D0.5141.00
275_K283_I0.5131.00
252_E261_R0.5121.00
247_E251_G0.5121.00
100_L149_V0.5111.00
97_A111_A0.5101.00
312_N319_L0.5101.00
264_I269_A0.5091.00
68_N72_P0.5091.00
26_V188_I0.5081.00
238_G241_F0.5081.00
301_F305_F0.5071.00
269_A272_L0.5061.00
301_F316_G0.5061.00
246_I250_H0.5061.00
285_G289_E0.5061.00
224_Y227_N0.5041.00
278_A282_M0.5041.00
6_F22_F0.5021.00
250_H257_N0.5011.00
294_M303_S0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1v43A 2 0.951 100 0.187 Contact Map
1g291 4 0.9891 100 0.191 Contact Map
2it1A 1 0.9755 100 0.192 Contact Map
2yyzA 1 0.97 100 0.197 Contact Map
3rlfA 2 0.9809 100 0.208 Contact Map
1oxxK 1 0.9319 100 0.208 Contact Map
3fvqA 2 0.9401 100 0.227 Contact Map
4tquS 2 0.9837 100 0.234 Contact Map
3d31A 2 0.9346 100 0.235 Contact Map
1z47A 2 0.9264 100 0.236 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0136 seconds.