PUCB - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

PUCB - Purine catabolism protein PucB

UniProt:	O32146	Sequences: MRSPYLIGVFLAAGKSRRMGQNKLALPLKGENIGSLSLKTALSSRLDHVLVVERTEHASLEWIGAPYHAPPFQKRWSLHVCQDAEKGQGHSVSSGVRKAESMGADGIVILLADQPQLSVDHLNALVALAPESFAVSSFLGAFTPPIYFSSTCFPYVKGLKGDEGARRLLKSGQLGAGAVLEAKDSGELDDIDTPEEYDMVRRAMS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	205 (184)
Sequences:	8628 (6600)
Seq/√Len:	486.6

ECOLI - MOCA MOBA GLMU
BACSU - PUCB MOBA GLMU
HALSA - Q9HR78
SULSO - Q97W15 Q7LXN3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
31_E	39_K	4.716	1.00
48_H	77_S	3.002	1.00
7_I	104_A	2.695	1.00
24_L	112_A	2.549	1.00
19_M	26_L	2.539	1.00
8_G	41_A	2.528	1.00
32_N	35_S	2.516	1.00
9_V	95_G	2.512	1.00
121_H	187_E	2.311	1.00
106_G	129_A	2.281	1.00
8_G	46_L	2.277	1.00
118_S	187_E	2.272	1.00
193_T	196_E	2.233	1.00
7_I	48_H	2.225	1.00
41_A	110_L	2.066	1.00
31_E	36_L	1.990	1.00
50_L	79_H	1.864	1.00
26_L	197_Y	1.817	1.00
86_K	90_H	1.811	1.00
191_I	200_V	1.766	1.00
116_Q	200_V	1.747	1.00
9_V	107_I	1.732	1.00
155_Y	171_S	1.710	1.00
35_S	39_K	1.686	1.00
110_L	122_L	1.677	1.00
111_L	114_Q	1.616	1.00
42_L	75_R	1.615	1.00
141_A	145_P	1.611	1.00
7_I	99_A	1.595	1.00
83_D	86_K	1.571	1.00
43_S	119_V	1.564	1.00
31_E	35_S	1.563	1.00
81_C	90_H	1.504	1.00
56_E	62_W	1.491	1.00
99_A	107_I	1.482	1.00
108_V	122_L	1.471	1.00
164_G	167_R	1.444	1.00
57_H	80_V	1.427	1.00
64_G	80_V	1.425	1.00
50_L	98_K	1.421	1.00
40_T	119_V	1.395	1.00
57_H	64_G	1.389	1.00
118_S	121_H	1.376	1.00
35_S	66_P	1.367	1.00
97_R	157_K	1.363	1.00
119_V	123_N	1.362	1.00
189_D	199_M	1.348	1.00
150_S	153_F	1.330	1.00
10_F	38_L	1.321	1.00
129_A	134_A	1.314	1.00
52_V	95_G	1.313	1.00
155_Y	172_G	1.299	1.00
96_V	157_K	1.294	1.00
92_V	109_I	1.283	1.00
142_F	145_P	1.265	1.00
90_H	93_S	1.265	1.00
53_E	57_H	1.262	1.00
168_L	172_G	1.242	1.00
15_K	85_E	1.238	1.00
110_L	117_L	1.237	1.00
133_F	172_G	1.234	1.00
189_D	200_V	1.229	1.00
16_S	21_Q	1.203	1.00
51_V	76_W	1.194	1.00
54_R	85_E	1.189	1.00
137_S	179_V	1.188	1.00
33_I	191_I	1.179	1.00
28_L	33_I	1.161	1.00
106_G	130_P	1.158	1.00
196_E	199_M	1.152	1.00
42_L	49_V	1.145	1.00
7_I	50_L	1.139	1.00
28_L	200_V	1.139	1.00
38_L	49_V	1.109	1.00
135_V	142_F	1.104	1.00
53_E	78_L	1.101	1.00
92_V	165_A	1.096	1.00
10_F	37_S	1.096	1.00
6_L	106_G	1.095	1.00
166_R	170_K	1.095	1.00
62_W	65_A	1.081	1.00
6_L	126_V	1.075	1.00
90_H	94_S	1.074	1.00
148_F	151_T	1.072	1.00
53_E	64_G	1.072	1.00
22_N	56_E	1.059	1.00
96_V	107_I	1.053	1.00
128_L	131_E	1.052	1.00
27_P	32_N	1.046	1.00
29_K	36_L	1.045	1.00
10_F	41_A	1.043	1.00
35_S	74_K	1.041	1.00
86_K	163_E	1.040	1.00
32_N	36_L	1.037	1.00
127_A	131_E	1.034	1.00
27_P	30_G	1.032	1.00
106_G	149_S	1.022	1.00
44_S	123_N	1.013	1.00
155_Y	158_G	1.010	1.00
64_G	78_L	1.008	1.00
149_S	152_C	1.006	1.00
77_S	98_K	1.005	1.00
93_S	157_K	0.992	1.00
83_D	90_H	0.989	1.00
19_M	194_P	0.986	1.00
96_V	153_F	0.984	1.00
140_G	145_P	0.982	1.00
38_L	76_W	0.982	1.00
198_D	201_R	0.980	1.00
133_F	136_S	0.974	1.00
133_F	137_S	0.960	1.00
9_V	52_V	0.955	1.00
103_G	150_S	0.954	1.00
53_E	80_V	0.948	1.00
37_S	40_T	0.947	1.00
77_S	80_V	0.942	1.00
36_L	40_T	0.941	1.00
123_N	127_A	0.929	1.00
152_C	155_Y	0.928	1.00
197_Y	201_R	0.922	1.00
155_Y	168_L	0.921	1.00
148_F	152_C	0.909	1.00
21_Q	194_P	0.907	1.00
128_L	178_A	0.906	1.00
45_R	123_N	0.901	1.00
32_N	66_P	0.900	1.00
137_S	181_E	0.898	1.00
132_S	176_A	0.895	1.00
178_A	181_E	0.895	1.00
93_S	97_R	0.894	1.00
9_V	109_I	0.890	1.00
79_H	94_S	0.890	1.00
124_A	127_A	0.890	1.00
106_G	147_Y	0.879	1.00
154_P	158_G	0.866	1.00
129_A	149_S	0.857	1.00
12_A	51_V	0.853	1.00
92_V	111_L	0.847	1.00
33_I	112_A	0.846	1.00
148_F	156_V	0.843	1.00
25_A	66_P	0.840	1.00
154_P	157_K	0.837	1.00
26_L	194_P	0.832	1.00
21_Q	26_L	0.828	1.00
16_S	24_L	0.826	1.00
191_I	197_Y	0.817	1.00
132_S	149_S	0.817	1.00
134_A	137_S	0.817	1.00
124_A	128_L	0.816	1.00
99_A	104_A	0.809	1.00
104_A	150_S	0.809	1.00
135_V	138_F	0.807	1.00
7_I	103_G	0.806	1.00
108_V	126_V	0.806	1.00
167_R	170_K	0.803	1.00
139_L	143_T	0.797	1.00
85_E	90_H	0.797	1.00
128_L	180_L	0.788	1.00
182_A	188_L	0.787	1.00
89_G	156_V	0.787	1.00
81_C	91_S	0.785	1.00
50_L	77_S	0.784	1.00
143_T	146_I	0.780	1.00
132_S	137_S	0.776	1.00
140_G	143_T	0.772	1.00
139_L	142_F	0.767	1.00
29_K	201_R	0.764	1.00
54_R	57_H	0.761	1.00
186_G	189_D	0.753	1.00
40_T	43_S	0.744	1.00
195_E	198_D	0.741	1.00
7_I	105_D	0.732	1.00
33_I	37_S	0.732	1.00
141_A	144_P	0.729	1.00
48_H	104_A	0.725	1.00
52_V	79_H	0.722	1.00
149_S	153_F	0.721	1.00
108_V	147_Y	0.720	1.00
152_C	172_G	0.717	1.00
120_D	123_N	0.716	1.00
120_D	124_A	0.714	1.00
151_T	154_P	0.714	1.00
139_L	145_P	0.713	1.00
21_Q	24_L	0.713	1.00
48_H	100_E	0.713	1.00
138_F	143_T	0.711	1.00
142_F	179_V	0.710	1.00
176_A	180_L	0.710	1.00
87_G	90_H	0.704	1.00
10_F	34_G	0.700	1.00
133_F	169_L	0.700	1.00
38_L	42_L	0.699	1.00
107_I	153_F	0.694	1.00
125_L	134_A	0.691	1.00
93_S	96_V	0.681	1.00
126_V	130_P	0.679	1.00
163_E	167_R	0.679	1.00
142_F	146_I	0.679	1.00
139_L	144_P	0.677	1.00
134_A	138_F	0.677	1.00
9_V	50_L	0.676	1.00
132_S	135_V	0.669	1.00
22_N	55_T	0.666	1.00
125_L	147_Y	0.666	1.00
9_V	99_A	0.665	1.00
126_V	129_A	0.664	1.00
132_S	136_S	0.663	1.00
16_S	197_Y	0.661	1.00
16_S	22_N	0.648	1.00
81_C	94_S	0.643	1.00
34_G	38_L	0.641	1.00
37_S	110_L	0.639	1.00
137_S	140_G	0.639	1.00
44_S	122_L	0.636	1.00
107_I	149_S	0.635	1.00
129_A	147_Y	0.634	1.00
37_S	41_A	0.633	1.00
35_S	73_Q	0.631	1.00
49_V	76_W	0.626	1.00
165_A	168_L	0.623	1.00
50_L	99_A	0.615	0.99
28_L	201_R	0.614	0.99
195_E	199_M	0.613	0.99
10_F	110_L	0.613	0.99
123_N	126_V	0.611	0.99
162_D	167_R	0.611	0.99
7_I	100_E	0.608	0.99
41_A	46_L	0.605	0.99
46_L	108_V	0.599	0.99
34_G	67_Y	0.596	0.99
79_H	95_G	0.595	0.99
194_P	198_D	0.591	0.99
156_V	168_L	0.590	0.99
88_Q	91_S	0.586	0.99
8_G	37_S	0.586	0.99
39_K	42_L	0.584	0.99
156_V	165_A	0.580	0.99
61_E	65_A	0.579	0.99
13_A	88_Q	0.578	0.99
52_V	94_S	0.576	0.99
33_I	197_Y	0.576	0.99
114_Q	188_L	0.576	0.99
52_V	81_C	0.573	0.99
27_P	31_E	0.572	0.99
34_G	51_V	0.569	0.99
52_V	91_S	0.569	0.99
166_R	169_L	0.568	0.99
14_G	18_R	0.564	0.99
124_A	180_L	0.562	0.99
75_R	78_L	0.559	0.99
6_L	46_L	0.557	0.99
19_M	197_Y	0.555	0.99
100_E	104_A	0.554	0.99
116_Q	189_D	0.552	0.99
27_P	197_Y	0.552	0.99
22_N	63_I	0.550	0.99
11_L	111_L	0.545	0.99
133_F	152_C	0.543	0.99
89_G	93_S	0.539	0.99
177_G	182_A	0.538	0.99
114_Q	144_P	0.537	0.99
132_S	152_C	0.536	0.99
170_K	173_Q	0.534	0.99
140_G	144_P	0.533	0.99
105_D	150_S	0.532	0.98
182_A	187_E	0.527	0.98
53_E	63_I	0.521	0.98
153_F	156_V	0.518	0.98
111_L	144_P	0.518	0.98
125_L	136_S	0.513	0.98
185_S	188_L	0.511	0.98
24_L	33_I	0.511	0.98
63_I	67_Y	0.510	0.98
164_G	190_D	0.508	0.98
27_P	201_R	0.506	0.98
22_N	25_A	0.500	0.98

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2weeA	1	0.9415	100	0.233	Contact Map
2wawA	1	0.9463	100	0.236	Contact Map
1e5kA	1	0.8829	100	0.275	Contact Map
3d5nA	2	0.8683	100	0.299	Contact Map
2e8bA	1	0.8439	100	0.306	Contact Map
3ngwA	2	0.8732	100	0.339	Contact Map
2xwlA	2	0.9171	100	0.426	Contact Map
4jd0A	1	0.9512	100	0.429	Contact Map
1vpaA	2	0.9268	100	0.429	Contact Map
1i52A	2	0.922	100	0.43	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0079 seconds.