PUCR - BACSU - GREMLIN Contacts

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PUCR - Purine catabolism regulatory protein

UniProt:	O32138	Sequences: MNILDVMKIPAFENANLIAGKAGGEREVQHVNMMDAPDIVDFLHKNELLVTTAYHLKDHPHQLSELIRQMAKRGCAGLGIKTKRYLEDIPKEIIELADSYAFPIIELPEHIRLGDIVNATLSHILDMRSNELQQAIYAHKKFTNHIMSGKGLQSLLKKVSDILQLPVLLLDQHAKMLSASHQISVETEKLKGTLNTVSGPFFTCFSTISDQKTYSVLPIYNHEKNCGYLLIPDMVQAGDKGLILTIEQAANVISFELLKENALKQFSRRARNEFFNNFIERTFSSDDEIKNRAKEFKLRWDQKYMCIAGKLDRNDESISFTENQLASDSVFEFLEGELSAFPFPPHFFMKGNVGIILIEATDSWSEMHASVISFLEQFQTQVSAQFKRTVSFGISNICQKLIDVPDAFTEASDALQSGHLSRSTAFIQVYHAKDVPELLRLLPVEDLKKFYNSTLQSLAEKQQEDQSLLHTLSVYLETHCQISETAKRLYVHRNTVIYRLEKCEELLGKSLKDPETTMRLRLALRMQRLIS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	531 (502)
Sequences:	2472 (1955)
Seq/√Len:	87.2

ECOLI - CDAR
BACSU - PUCR ADER YCGP

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
395_S	407_A	10.372	1.00
478_T	488_R	6.402	1.00
4_L	25_E	5.295	1.00
467_S	470_H	4.649	1.00
504_E	510_S	4.622	1.00
393_G	414_A	4.230	1.00
91_K	95_E	4.170	1.00
462_Q	466_Q	4.162	1.00
16_N	106_E	4.142	1.00
48_L	77_G	3.934	1.00
461_K	464_E	3.932	1.00
515_E	525_R	3.856	1.00
393_G	411_A	3.575	1.00
485_T	496_V	3.529	1.00
3_I	77_G	3.253	1.00
491_V	496_V	3.198	1.00
94_I	104_I	3.154	1.00
59_H	62_Q	3.134	1.00
97_A	104_I	3.058	1.00
458_L	503_C	2.967	1.00
156_L	169_L	2.966	1.00
472_L	503_C	2.963	1.00
17_L	24_G	2.912	1.00
308_A	411_A	2.909	1.00
471_T	503_C	2.824	1.00
171_D	175_K	2.794	1.00
470_H	474_V	2.735	1.00
68_R	100_Y	2.686	1.00
471_T	496_V	2.638	1.00
19_A	98_D	2.636	1.00
159_V	249_A	2.529	1.00
396_N	410_E	2.505	1.00
17_L	20_G	2.473	1.00
474_V	485_T	2.426	1.00
492_H	495_T	2.385	1.00
484_E	487_K	2.364	1.00
461_K	466_Q	2.352	1.00
79_G	107_L	2.348	1.00
478_T	485_T	2.310	1.00
447_L	526_M	2.301	1.00
471_T	499_R	2.281	1.00
68_R	96_L	2.264	1.00
471_T	485_T	2.199	1.00
513_D	516_T	2.186	1.00
509_K	516_T	2.112	1.00
34_M	49_L	2.098	1.00
6_V	28_V	2.087	1.00
355_I	408_F	2.084	1.00
71_A	100_Y	2.070	1.00
71_A	102_F	2.068	1.00
480_C	517_T	2.041	1.00
407_A	411_A	2.034	1.00
507_L	516_T	1.970	1.00
491_V	495_T	1.966	1.00
477_E	488_R	1.964	1.00
95_E	98_D	1.933	1.00
458_L	469_L	1.925	1.00
15_A	105_I	1.916	1.00
504_E	511_L	1.916	1.00
49_L	75_C	1.911	1.00
70_M	78_L	1.909	1.00
48_L	79_G	1.909	1.00
239_D	242_L	1.877	1.00
67_I	97_A	1.873	1.00
48_L	105_I	1.872	1.00
482_I	500_L	1.834	1.00
504_E	512_K	1.816	1.00
502_K	506_L	1.803	1.00
96_L	100_Y	1.800	1.00
493_R	497_I	1.796	1.00
78_L	102_F	1.791	1.00
96_L	99_S	1.787	1.00
152_L	253_I	1.783	1.00
473_S	477_E	1.779	1.00
22_A	101_A	1.759	1.00
68_R	99_S	1.744	1.00
26_R	103_P	1.731	1.00
64_S	96_L	1.725	1.00
216_V	228_Y	1.679	1.00
95_E	99_S	1.662	1.00
353_V	412_S	1.657	1.00
256_E	259_K	1.651	1.00
20_G	98_D	1.621	1.00
456_Q	460_E	1.618	1.00
18_I	106_E	1.607	1.00
398_C	407_A	1.601	1.00
4_L	8_K	1.592	1.00
20_G	23_G	1.583	1.00
500_L	503_C	1.579	1.00
136_I	140_K	1.562	1.00
60_P	92_E	1.554	1.00
163_L	245_T	1.547	1.00
82_T	106_E	1.543	1.00
398_C	410_E	1.536	1.00
277_N	292_R	1.527	1.00
462_Q	469_L	1.526	1.00
484_E	488_R	1.525	1.00
309_G	392_F	1.516	1.00
403_D	406_D	1.501	1.00
67_I	100_Y	1.497	1.00
145_H	150_K	1.493	1.00
372_I	376_E	1.490	1.00
151_G	154_S	1.487	0.99
275_F	357_L	1.486	0.99
16_N	108_P	1.475	0.99
23_G	98_D	1.465	0.99
307_I	356_I	1.459	0.99
68_R	72_K	1.456	0.99
17_L	23_G	1.455	0.99
20_G	26_R	1.439	0.99
4_L	24_G	1.439	0.99
63_L	92_E	1.434	0.99
454_T	457_S	1.434	0.99
494_N	497_I	1.431	0.99
357_L	404_V	1.430	0.99
400_K	403_D	1.419	0.99
29_Q	46_N	1.416	0.99
76_A	103_P	1.411	0.99
26_R	76_A	1.404	0.99
65_E	69_Q	1.403	0.99
12_F	116_I	1.401	0.99
21_K	98_D	1.400	0.99
457_S	507_L	1.397	0.99
34_M	66_L	1.387	0.99
306_C	411_A	1.383	0.99
79_G	105_I	1.378	0.99
18_I	89_I	1.377	0.99
462_Q	465_D	1.371	0.99
347_F	356_I	1.369	0.99
169_L	229_L	1.367	0.99
94_I	98_D	1.365	0.99
42_F	81_K	1.362	0.99
418_G	428_Q	1.360	0.99
406_D	410_E	1.313	0.99
489_L	496_V	1.309	0.99
452_N	456_Q	1.307	0.99
310_K	419_H	1.300	0.99
156_L	167_V	1.289	0.99
457_S	506_L	1.279	0.98
405_P	409_T	1.278	0.98
476_L	480_C	1.275	0.98
395_S	398_C	1.268	0.98
156_L	227_G	1.264	0.98
463_Q	466_Q	1.254	0.98
502_K	505_E	1.236	0.98
501_E	504_E	1.213	0.98
408_F	412_S	1.209	0.98
507_L	520_L	1.209	0.98
151_G	256_E	1.204	0.98
7_M	105_I	1.198	0.98
36_A	39_I	1.197	0.98
478_T	484_E	1.195	0.98
67_I	93_I	1.193	0.98
35_D	83_K	1.185	0.97
26_R	71_A	1.183	0.97
476_L	517_T	1.182	0.97
307_I	394_I	1.179	0.97
114_G	121_L	1.177	0.97
117_V	121_L	1.171	0.97
80_I	89_I	1.170	0.97
158_K	161_D	1.169	0.97
189_K	193_T	1.167	0.97
219_I	254_S	1.166	0.97
192_G	196_T	1.165	0.97
30_H	121_L	1.165	0.97
153_Q	157_K	1.159	0.97
19_A	23_G	1.153	0.97
355_I	412_S	1.152	0.97
475_Y	500_L	1.151	0.97
459_A	469_L	1.149	0.97
47_E	113_L	1.148	0.97
34_M	39_I	1.148	0.97
19_A	22_A	1.143	0.97
194_L	199_G	1.139	0.97
492_H	497_I	1.135	0.97
134_Q	242_L	1.133	0.97
30_H	118_N	1.130	0.97
474_V	478_T	1.130	0.97
39_I	49_L	1.129	0.97
460_E	463_Q	1.128	0.97
70_M	75_C	1.124	0.97
3_I	23_G	1.124	0.97
290_K	293_A	1.122	0.96
48_L	103_P	1.115	0.96
138_A	245_T	1.114	0.96
118_N	122_S	1.110	0.96
170_L	230_L	1.108	0.96
20_G	103_P	1.101	0.96
190_L	193_T	1.086	0.96
461_K	467_S	1.082	0.96
276_N	350_K	1.080	0.96
475_Y	480_C	1.076	0.96
67_I	78_L	1.076	0.96
306_C	407_A	1.071	0.95
81_K	113_L	1.070	0.95
504_E	508_G	1.069	0.95
193_T	196_T	1.069	0.95
411_A	414_A	1.064	0.95
53_A	113_L	1.062	0.95
112_R	115_D	1.050	0.95
475_Y	482_I	1.044	0.95
193_T	197_V	1.043	0.95
118_N	121_L	1.039	0.95
354_G	526_M	1.035	0.94
498_Y	502_K	1.034	0.94
50_V	124_I	1.034	0.94
35_D	113_L	1.034	0.94
270_A	493_R	1.033	0.94
101_A	104_I	1.030	0.94
393_G	410_E	1.029	0.94
7_M	10_P	1.028	0.94
56_L	63_L	1.026	0.94
30_H	47_E	1.025	0.94
503_C	507_L	1.020	0.94
246_I	250_A	1.016	0.94
373_S	377_Q	1.010	0.94
30_H	113_L	1.010	0.94
474_V	489_L	1.009	0.94
275_F	278_F	1.003	0.93
482_I	492_H	0.995	0.93
398_C	403_D	0.989	0.93
269_R	273_E	0.986	0.93
121_L	125_L	0.979	0.93
51_T	113_L	0.977	0.93
518_M	521_R	0.976	0.93
158_K	162_I	0.971	0.92
19_A	103_P	0.968	0.92
393_G	418_G	0.968	0.92
156_L	178_S	0.967	0.92
214_Y	230_L	0.967	0.92
23_G	26_R	0.967	0.92
30_H	494_N	0.965	0.92
6_V	15_A	0.963	0.92
15_A	79_G	0.962	0.92
277_N	282_T	0.960	0.92
481_Q	493_R	0.954	0.92
482_I	494_N	0.953	0.92
462_Q	467_S	0.953	0.92
479_H	517_T	0.952	0.92
414_A	418_G	0.950	0.92
35_D	54_Y	0.948	0.91
479_H	514_P	0.948	0.91
435_V	522_L	0.947	0.91
32_N	113_L	0.946	0.91
141_K	158_K	0.936	0.91
93_I	97_A	0.934	0.91
32_N	494_N	0.930	0.91
64_S	99_S	0.928	0.91
468_L	503_C	0.927	0.90
116_I	120_T	0.926	0.90
39_I	81_K	0.923	0.90
72_K	100_Y	0.923	0.90
129_S	132_L	0.920	0.90
305_M	431_H	0.917	0.90
310_K	353_V	0.914	0.90
160_S	180_S	0.909	0.90
125_L	496_V	0.904	0.89
189_K	198_S	0.903	0.89
136_I	139_H	0.901	0.89
38_D	42_F	0.901	0.89
509_K	520_L	0.901	0.89
2_N	5_D	0.896	0.89
159_V	245_T	0.896	0.89
472_L	476_L	0.895	0.89
163_L	179_A	0.895	0.89
53_A	79_G	0.894	0.89
482_I	497_I	0.891	0.89
477_E	515_E	0.891	0.89
434_D	437_E	0.891	0.89
191_K	198_S	0.890	0.89
475_Y	504_E	0.889	0.89
492_H	498_Y	0.889	0.89
163_L	242_L	0.887	0.88
81_K	107_L	0.886	0.88
29_Q	118_N	0.884	0.88
166_P	232_P	0.883	0.88
34_M	42_F	0.881	0.88
451_Y	456_Q	0.880	0.88
42_F	54_Y	0.879	0.88
456_Q	523_A	0.875	0.88
24_G	27_E	0.873	0.88
32_N	117_V	0.870	0.87
415_L	419_H	0.870	0.87
67_I	102_F	0.869	0.87
52_T	147_M	0.866	0.87
266_F	270_A	0.865	0.87
36_A	113_L	0.863	0.87
32_N	81_K	0.862	0.87
42_F	51_T	0.862	0.87
157_K	180_S	0.862	0.87
481_Q	484_E	0.862	0.87
88_D	91_K	0.860	0.87
451_Y	494_N	0.857	0.87
299_R	302_Q	0.854	0.86
81_K	84_R	0.852	0.86
380_T	383_S	0.851	0.86
54_Y	81_K	0.851	0.86
33_M	117_V	0.850	0.86
373_S	376_E	0.850	0.86
167_V	246_I	0.848	0.86
32_N	49_L	0.848	0.86
289_I	296_F	0.847	0.86
393_G	415_L	0.846	0.86
436_P	525_R	0.846	0.86
104_I	291_N	0.844	0.86
43_L	51_T	0.843	0.86
250_A	526_M	0.839	0.86
188_E	192_G	0.838	0.85
482_I	496_V	0.837	0.85
308_A	415_L	0.836	0.85
139_H	247_E	0.834	0.85
32_N	47_E	0.834	0.85
81_K	497_I	0.832	0.85
194_L	200_P	0.832	0.85
30_H	81_K	0.831	0.85
11_A	15_A	0.830	0.85
189_K	197_V	0.828	0.85
93_I	96_L	0.827	0.85
79_G	252_V	0.826	0.85
107_L	492_H	0.821	0.84
65_E	68_R	0.820	0.84
268_R	335_E	0.819	0.84
167_V	170_L	0.818	0.84
447_L	450_F	0.818	0.84
4_L	21_K	0.817	0.84
107_L	497_I	0.816	0.84
79_G	108_P	0.815	0.84
107_L	116_I	0.814	0.84
308_A	524_L	0.812	0.84
306_C	395_S	0.811	0.84
308_A	393_G	0.810	0.83
481_Q	496_V	0.810	0.83
93_I	104_I	0.805	0.83
19_A	97_A	0.805	0.83
192_G	195_N	0.804	0.83
66_L	494_N	0.802	0.83
32_N	53_A	0.801	0.83
42_F	492_H	0.798	0.83
37_P	81_K	0.795	0.82
391_S	419_H	0.795	0.82
514_P	518_M	0.794	0.82
471_T	491_V	0.793	0.82
293_A	296_F	0.791	0.82
310_K	352_N	0.788	0.82
395_S	411_A	0.787	0.82
3_I	160_S	0.785	0.82
18_I	98_D	0.782	0.81
108_P	492_H	0.782	0.81
435_V	450_F	0.781	0.81
231_I	246_I	0.781	0.81
308_A	353_V	0.780	0.81
308_A	355_I	0.779	0.81
248_Q	494_N	0.779	0.81
64_S	100_Y	0.778	0.81
142_F	522_L	0.778	0.81
169_L	253_I	0.778	0.81
471_T	498_Y	0.778	0.81
46_N	73_R	0.774	0.81
510_S	516_T	0.774	0.81
517_T	521_R	0.774	0.81
49_L	475_Y	0.773	0.81
479_H	513_D	0.773	0.81
82_T	502_K	0.772	0.80
452_N	460_E	0.772	0.80
399_Q	403_D	0.768	0.80
247_E	444_V	0.767	0.80
55_H	83_K	0.766	0.80
113_L	493_R	0.766	0.80
15_A	107_L	0.764	0.80
6_V	147_M	0.764	0.80
468_L	471_T	0.764	0.80
219_I	227_G	0.763	0.80
53_A	56_L	0.761	0.79
468_L	506_L	0.760	0.79
51_T	78_L	0.760	0.79
81_K	494_N	0.758	0.79
445_E	448_K	0.758	0.79
480_C	493_R	0.756	0.79
249_A	476_L	0.755	0.79
312_D	391_S	0.754	0.79
46_N	74_G	0.752	0.79
375_L	378_F	0.752	0.79
18_I	94_I	0.749	0.78
40_V	69_Q	0.747	0.78
86_L	90_P	0.747	0.78
32_N	112_R	0.747	0.78
64_S	67_I	0.746	0.78
361_T	399_Q	0.746	0.78
34_M	44_H	0.745	0.78
219_I	253_I	0.745	0.78
64_S	484_E	0.743	0.78
475_Y	503_C	0.742	0.78
187_T	190_L	0.738	0.77
80_I	86_L	0.737	0.77
151_G	171_D	0.737	0.77
76_A	181_H	0.735	0.77
39_I	73_R	0.733	0.77
32_N	42_F	0.732	0.77
77_G	124_I	0.729	0.76
177_L	514_P	0.728	0.76
3_I	9_I	0.728	0.76
471_T	502_K	0.727	0.76
66_L	113_L	0.726	0.76
46_N	76_A	0.726	0.76
160_S	165_L	0.724	0.76
81_K	492_H	0.723	0.76
61_H	92_E	0.721	0.76
429_V	432_A	0.721	0.76
98_D	352_N	0.721	0.76
229_L	417_S	0.721	0.76
233_D	236_Q	0.718	0.75
436_P	515_E	0.718	0.75
262_A	485_T	0.717	0.75
397_I	401_L	0.717	0.75
474_V	477_E	0.716	0.75
214_Y	217_L	0.715	0.75
405_P	486_A	0.714	0.75
37_P	85_Y	0.714	0.75
168_L	474_V	0.714	0.75
448_K	452_N	0.713	0.75
139_H	256_E	0.712	0.75
176_M	193_T	0.711	0.75
501_E	505_E	0.709	0.74
111_I	115_D	0.709	0.74
248_Q	492_H	0.709	0.74
6_V	120_T	0.709	0.74
43_L	66_L	0.708	0.74
171_D	481_Q	0.707	0.74
194_L	197_V	0.705	0.74
37_P	42_F	0.704	0.74
297_K	300_W	0.704	0.74
455_L	523_A	0.704	0.74
334_L	354_G	0.702	0.74
167_V	231_I	0.701	0.74
138_A	162_I	0.701	0.74
37_P	84_R	0.700	0.74
482_I	493_R	0.697	0.73
476_L	521_R	0.697	0.73
469_L	524_L	0.696	0.73
514_P	517_T	0.695	0.73
33_M	43_L	0.694	0.73
24_G	28_V	0.693	0.73
49_L	94_I	0.692	0.73
471_T	495_T	0.690	0.72
37_P	54_Y	0.689	0.72
491_V	508_G	0.687	0.72
234_M	345_P	0.685	0.72
5_D	123_H	0.684	0.72
483_S	493_R	0.683	0.72
67_I	98_D	0.683	0.72
53_A	66_L	0.682	0.72
36_A	54_Y	0.682	0.72
165_L	233_D	0.681	0.72
62_Q	95_E	0.680	0.71
98_D	377_Q	0.679	0.71
394_I	429_V	0.675	0.71
17_L	105_I	0.674	0.71
31_V	42_F	0.672	0.70
374_F	382_V	0.672	0.70
17_L	27_E	0.671	0.70
50_V	53_A	0.671	0.70
52_T	83_K	0.670	0.70
432_A	437_E	0.670	0.70
29_Q	297_K	0.670	0.70
498_Y	521_R	0.670	0.70
443_P	450_F	0.669	0.70
512_K	520_L	0.668	0.70
435_V	525_R	0.665	0.70
404_V	407_A	0.665	0.70
124_I	454_T	0.665	0.70
179_A	227_G	0.664	0.70
108_P	494_N	0.662	0.69
116_I	437_E	0.661	0.69
216_V	525_R	0.660	0.69
253_I	256_E	0.658	0.69
414_A	433_K	0.657	0.69
374_F	378_F	0.656	0.69
137_Y	141_K	0.656	0.69
42_F	97_A	0.655	0.69
107_L	111_I	0.653	0.68
156_L	162_I	0.652	0.68
461_K	469_L	0.652	0.68
226_C	492_H	0.652	0.68
186_E	193_T	0.650	0.68
284_S	360_A	0.648	0.68
396_N	431_H	0.647	0.68
450_F	509_K	0.646	0.67
471_T	489_L	0.645	0.67
192_G	387_K	0.645	0.67
78_L	468_L	0.645	0.67
86_L	89_I	0.645	0.67
30_H	493_R	0.644	0.67
165_L	231_I	0.643	0.67
337_E	340_A	0.642	0.67
32_N	121_L	0.642	0.67
470_H	477_E	0.641	0.67
163_L	166_P	0.640	0.67
466_Q	469_L	0.640	0.67
40_V	66_L	0.639	0.67
72_K	102_F	0.639	0.67
61_H	78_L	0.638	0.67
494_N	518_M	0.637	0.66
229_L	250_A	0.637	0.66
83_K	86_L	0.636	0.66
42_F	113_L	0.634	0.66
276_N	280_E	0.634	0.66
37_P	55_H	0.634	0.66
229_L	246_I	0.633	0.66
469_L	503_C	0.631	0.66
430_Y	440_R	0.630	0.66
142_F	249_A	0.629	0.65
292_R	296_F	0.629	0.65
186_E	192_G	0.629	0.65
81_K	121_L	0.626	0.65
137_Y	178_S	0.625	0.65
97_A	103_P	0.625	0.65
131_E	241_G	0.625	0.65
305_M	360_A	0.624	0.65
17_L	103_P	0.624	0.65
9_I	119_A	0.624	0.65
15_A	39_I	0.623	0.65
126_D	129_S	0.622	0.65
165_L	253_I	0.621	0.64
8_K	11_A	0.621	0.64
477_E	521_R	0.620	0.64
91_K	312_D	0.620	0.64
11_A	119_A	0.619	0.64
461_K	506_L	0.619	0.64
21_K	103_P	0.617	0.64
34_M	37_P	0.616	0.64
354_G	438_L	0.616	0.64
66_L	70_M	0.615	0.64
212_K	232_P	0.614	0.64
442_L	450_F	0.614	0.64
267_S	443_P	0.612	0.63
461_K	465_D	0.612	0.63
236_Q	287_D	0.611	0.63
504_E	507_L	0.611	0.63
3_I	26_R	0.611	0.63
115_D	119_A	0.610	0.63
281_R	405_P	0.610	0.63
77_G	279_I	0.609	0.63
52_T	97_A	0.609	0.63
77_G	160_S	0.609	0.63
36_A	70_M	0.608	0.63
512_K	515_E	0.607	0.63
141_K	161_D	0.606	0.63
462_Q	506_L	0.605	0.62
28_V	76_A	0.605	0.62
435_V	438_L	0.604	0.62
62_Q	65_E	0.603	0.62
116_I	438_L	0.603	0.62
55_H	63_L	0.602	0.62
77_G	105_I	0.602	0.62
174_A	196_T	0.602	0.62
171_D	177_L	0.601	0.62
195_N	198_S	0.601	0.62
47_E	115_D	0.600	0.62
204_C	209_S	0.600	0.62
34_M	81_K	0.598	0.62
434_D	450_F	0.597	0.61
32_N	497_I	0.596	0.61
12_F	15_A	0.596	0.61
475_Y	521_R	0.596	0.61
119_A	124_I	0.595	0.61
30_H	117_V	0.593	0.61
2_N	27_E	0.593	0.61
203_T	206_S	0.592	0.61
189_K	192_G	0.592	0.61
443_P	446_D	0.592	0.61
163_L	416_Q	0.591	0.61
15_A	49_L	0.590	0.61
434_D	519_R	0.590	0.61
67_I	104_I	0.590	0.61
135_A	248_Q	0.589	0.60
91_K	94_I	0.589	0.60
17_L	21_K	0.588	0.60
122_S	254_S	0.587	0.60
35_D	526_M	0.587	0.60
104_I	457_S	0.586	0.60
414_A	430_Y	0.585	0.60
50_V	113_L	0.585	0.60
489_L	492_H	0.584	0.60
28_V	144_N	0.584	0.60
493_R	507_L	0.583	0.60
22_A	67_I	0.583	0.60
263_L	266_F	0.582	0.59
81_K	482_I	0.581	0.59
313_R	317_S	0.581	0.59
65_E	104_I	0.581	0.59
308_A	408_F	0.580	0.59
51_T	54_Y	0.579	0.59
195_N	200_P	0.578	0.59
334_L	346_H	0.577	0.59
307_I	511_L	0.577	0.59
338_L	510_S	0.577	0.59
198_S	202_F	0.576	0.59
135_A	138_A	0.576	0.59
74_G	123_H	0.574	0.58
113_L	121_L	0.574	0.58
393_G	439_L	0.572	0.58
33_M	113_L	0.572	0.58
337_E	381_Q	0.571	0.58
425_A	486_A	0.570	0.58
509_K	519_R	0.570	0.58
332_E	336_G	0.568	0.58
507_L	515_E	0.568	0.58
169_L	219_I	0.567	0.57
383_S	387_K	0.566	0.57
357_L	360_A	0.565	0.57
51_T	56_L	0.565	0.57
345_P	526_M	0.564	0.57
333_F	336_G	0.564	0.57
10_P	522_L	0.564	0.57
128_R	131_E	0.563	0.57
108_P	120_T	0.563	0.57
522_L	525_R	0.562	0.57
152_L	177_L	0.561	0.57
3_I	19_A	0.561	0.57
391_S	423_S	0.560	0.57
468_L	482_I	0.559	0.56
451_Y	526_M	0.558	0.56
329_S	357_L	0.558	0.56
170_L	174_A	0.557	0.56
113_L	497_I	0.557	0.56
288_E	307_I	0.557	0.56
80_I	84_R	0.557	0.56
372_I	382_V	0.557	0.56
450_F	523_A	0.555	0.56
146_I	255_F	0.554	0.56
32_N	50_V	0.554	0.56
82_T	480_C	0.553	0.56
205_F	211_Q	0.552	0.56
15_A	112_R	0.552	0.56
161_D	183_I	0.550	0.55
329_S	397_I	0.550	0.55
77_G	84_R	0.549	0.55
439_L	522_L	0.549	0.55
521_R	525_R	0.548	0.55
278_F	411_A	0.547	0.55
52_T	113_L	0.547	0.55
353_V	390_V	0.546	0.55
81_K	493_R	0.546	0.55
55_H	81_K	0.546	0.55
143_T	156_L	0.545	0.55
244_L	255_F	0.545	0.55
315_D	391_S	0.545	0.55
30_H	114_G	0.545	0.55
65_E	72_K	0.544	0.54
314_N	445_E	0.544	0.54
307_I	428_Q	0.544	0.54
35_D	51_T	0.544	0.54
306_C	398_C	0.544	0.54
151_G	230_L	0.543	0.54
56_L	75_C	0.542	0.54
474_V	488_R	0.541	0.54
274_F	281_R	0.541	0.54
480_C	485_T	0.541	0.54
471_T	494_N	0.541	0.54
395_S	414_A	0.541	0.54
456_Q	507_L	0.540	0.54
306_C	355_I	0.540	0.54
262_A	268_R	0.540	0.54
206_S	394_I	0.539	0.54
124_I	169_L	0.539	0.54
414_A	525_R	0.539	0.54
224_K	261_N	0.538	0.54
440_R	449_K	0.538	0.54
221_N	251_N	0.538	0.54
497_I	517_T	0.538	0.54
263_L	270_A	0.537	0.53
36_A	81_K	0.537	0.53
437_E	440_R	0.537	0.53
301_D	304_Y	0.536	0.53
21_K	26_R	0.535	0.53
149_G	256_E	0.535	0.53
476_L	495_T	0.535	0.53
170_L	217_L	0.534	0.53
234_M	412_S	0.534	0.53
166_P	293_A	0.533	0.53
81_K	118_N	0.533	0.53
248_Q	255_F	0.532	0.53
81_K	108_P	0.532	0.53
278_F	309_G	0.531	0.53
42_F	102_F	0.531	0.53
444_V	447_L	0.530	0.53
336_G	340_A	0.530	0.53
54_Y	84_R	0.530	0.53
156_L	240_K	0.530	0.53
379_Q	392_F	0.529	0.52
136_I	251_N	0.529	0.52
455_L	459_A	0.528	0.52
186_E	189_K	0.528	0.52
509_K	512_K	0.528	0.52
50_V	81_K	0.527	0.52
281_R	508_G	0.527	0.52
238_G	242_L	0.526	0.52
395_S	410_E	0.525	0.52
176_M	180_S	0.525	0.52
35_D	163_L	0.525	0.52
156_L	253_I	0.523	0.52
170_L	214_Y	0.523	0.52
341_F	377_Q	0.523	0.52
200_P	338_L	0.523	0.52
5_D	28_V	0.520	0.51
160_S	167_V	0.520	0.51
191_K	201_F	0.518	0.51
121_L	129_S	0.518	0.51
302_Q	344_P	0.518	0.51
248_Q	251_N	0.517	0.51
410_E	458_L	0.516	0.51
138_A	145_H	0.515	0.51
102_F	145_H	0.513	0.50
77_G	330_V	0.511	0.50
287_D	291_N	0.510	0.50
378_F	452_N	0.510	0.50
178_S	249_A	0.510	0.50
94_I	126_D	0.510	0.50
125_L	128_R	0.510	0.50
221_N	226_C	0.509	0.50
487_K	495_T	0.509	0.50
276_N	348_F	0.509	0.50
483_S	487_K	0.509	0.50
242_L	479_H	0.509	0.50
116_I	343_F	0.509	0.50
439_L	498_Y	0.509	0.50
6_V	91_K	0.509	0.50
263_L	274_F	0.508	0.50
509_K	513_D	0.508	0.50
38_D	70_M	0.508	0.50
17_L	100_Y	0.507	0.49
97_A	471_T	0.507	0.49
437_E	446_D	0.507	0.49
377_Q	381_Q	0.507	0.49
259_K	418_G	0.506	0.49
163_L	231_I	0.505	0.49
139_H	519_R	0.505	0.49
180_S	227_G	0.504	0.49
158_K	253_I	0.504	0.49
23_G	279_I	0.503	0.49
94_I	339_S	0.503	0.49
298_L	304_Y	0.503	0.49
45_K	114_G	0.503	0.49
163_L	167_V	0.503	0.49
218_P	228_Y	0.501	0.49
125_L	503_C	0.501	0.49
51_T	66_L	0.501	0.49
188_E	193_T	0.501	0.49
91_K	394_I	0.501	0.49
496_V	499_R	0.501	0.49
459_A	500_L	0.500	0.48
481_Q	494_N	0.500	0.48
331_F	335_E	0.500	0.48

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3onqA	5	0.4765	100	0.634	Contact Map
2gx5A	2	0.2561	98.4	0.908	Contact Map
2iojA	1	0.2109	98.2	0.912	Contact Map
4eu0A	1	0.4802	97.4	0.928	Contact Map
1ko7A	3	0.4557	96.5	0.936	Contact Map
3ispA	3	0.1243	95.8	0.94	Contact Map
1al3A	1	0	95.7	0.94	Contact Map
2w1rA	2	0.1959	95.7	0.94	Contact Map
3mz1A	2	0	95.6	0.941	Contact Map
1knxA	5	0.4783	95.5	0.941	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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