GREMLIN Database
YUTJ - NADH dehydrogenase-like protein YutJ
UniProt: O32117 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 355 (289)
Sequences: 56388 (40757)
Seq/√Len: 2397.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
145_A224_A4.2981.00
143_T168_N3.5551.00
36_R75_D3.4121.00
3_K30_S3.1411.00
170_I202_I3.0721.00
168_N200_R2.8651.00
211_E215_V2.7541.00
3_K97_D2.6001.00
32_T72_Q2.5751.00
4_L20_L2.5331.00
16_V100_I2.4541.00
85_Q93_P2.4421.00
108_K234_Q2.4181.00
255_T259_N2.3671.00
191_Q195_E2.3481.00
145_A172_F2.3471.00
143_T225_D2.3121.00
84_K265_H2.2901.00
143_T170_I2.2871.00
215_V221_P2.2661.00
34_I94_I2.2591.00
209_K215_V2.2261.00
245_E253_V2.2141.00
86_V90_D2.1291.00
202_I220_D2.1141.00
5_V34_I2.1061.00
87_L93_P2.0151.00
113_P209_K1.9891.00
81_I263_D1.9661.00
170_I200_R1.9441.00
3_K32_T1.9401.00
100_I295_L1.9261.00
211_E221_P1.9211.00
80_D83_Q1.9071.00
174_R206_N1.8781.00
143_T167_L1.8761.00
74_G90_D1.8341.00
5_V96_Y1.8331.00
98_D265_H1.8241.00
247_D251_R1.8211.00
12_G269_V1.7771.00
85_Q95_S1.7681.00
245_E262_G1.7501.00
96_Y99_A1.7451.00
5_V94_I1.7371.00
142_A225_D1.7061.00
30_S70_D1.6861.00
55_S58_H1.6831.00
106_E234_Q1.6761.00
172_F222_I1.6741.00
106_E236_N1.6621.00
56_D63_F1.6331.00
143_T223_S1.6221.00
98_D295_L1.5951.00
103_L272_C1.5631.00
176_N204_R1.5391.00
5_V86_V1.5301.00
202_I205_A1.5221.00
5_V32_T1.5161.00
98_D267_Y1.5121.00
60_R63_F1.4921.00
56_D60_R1.4781.00
100_I269_V1.4771.00
78_S87_L1.4671.00
208_T215_V1.4641.00
205_A218_H1.4101.00
267_Y294_I1.4041.00
292_V296_Q1.3901.00
124_T127_Q1.3861.00
17_L33_L1.3851.00
210_V227_I1.3751.00
259_N264_E1.3451.00
78_S241_D1.3311.00
126_D129_R1.3301.00
170_I224_A1.3261.00
9_G35_D1.3231.00
59_I63_F1.3211.00
6_L13_N1.3021.00
32_T70_D1.3011.00
111_N115_A1.2921.00
193_W196_E1.2891.00
254_L273_A1.2831.00
288_A292_V1.2801.00
12_G284_A1.2761.00
144_V160_L1.2661.00
206_N217_N1.2621.00
4_L29_V1.2571.00
128_S131_T1.2531.00
252_I268_V1.2431.00
141_N167_L1.2391.00
57_H61_V1.2391.00
145_A214_V1.2391.00
4_L100_I1.2341.00
75_D89_Q1.2311.00
205_A220_D1.2281.00
55_S59_I1.2191.00
21_L69_L1.2161.00
149_A173_D1.2071.00
45_E48_A1.1931.00
74_G89_Q1.1821.00
56_D59_I1.1801.00
144_V226_A1.1731.00
59_I62_S1.1721.00
80_D87_L1.1711.00
173_D203_N1.1611.00
61_V65_E1.1571.00
291_I295_L1.1541.00
98_D298_R1.1521.00
6_L17_L1.1511.00
125_I129_R1.1461.00
102_G269_V1.1431.00
193_W197_H1.1321.00
32_T94_I1.1301.00
58_H62_S1.1301.00
19_R289_E1.1271.00
297_K302_E1.1251.00
62_S65_E1.1221.00
19_R22_P1.1101.00
48_A51_A1.1051.00
191_Q203_N1.1041.00
127_Q130_E1.1041.00
188_K191_Q1.0981.00
76_I79_I1.0961.00
290_Q294_I1.0951.00
81_I84_K1.0911.00
122_I126_D1.0861.00
184_E188_K1.0801.00
208_T219_D1.0791.00
162_E197_H1.0781.00
81_I266_L1.0751.00
4_L98_D1.0611.00
55_S62_S1.0561.00
208_T217_N1.0551.00
192_K196_E1.0511.00
19_R293_Q1.0511.00
269_V291_I1.0511.00
161_R199_V1.0421.00
124_T128_S1.0401.00
154_V171_L1.0391.00
170_I222_I1.0361.00
267_Y298_R1.0291.00
72_Q94_I1.0231.00
88_F94_I1.0221.00
80_D85_Q1.0201.00
161_R168_N1.0171.00
252_I272_C1.0171.00
49_L52_G1.0151.00
7_I103_L1.0111.00
188_K192_K1.0041.00
58_H61_V1.0031.00
144_V167_L1.0031.00
125_I128_S1.0011.00
263_D266_L0.9981.00
128_S132_Y0.9981.00
7_I76_I0.9961.00
189_Y193_W0.9951.00
237_K241_D0.9951.00
126_D130_E0.9881.00
29_V296_Q0.9841.00
157_A171_L0.9791.00
50_A53_T0.9761.00
77_T89_Q0.9751.00
247_D253_V0.9741.00
205_A217_N0.9711.00
216_Y222_I0.9701.00
192_K195_E0.9681.00
145_A222_I0.9671.00
166_D169_I0.9641.00
254_L268_V0.9621.00
237_K240_R0.9571.00
60_R64_P0.9541.00
88_F92_E0.9481.00
56_D62_S0.9481.00
254_L258_H0.9471.00
177_L187_S0.9431.00
106_E237_K0.9381.00
147_V227_I0.9361.00
3_K95_S0.9321.00
34_I72_Q0.9281.00
59_I64_P0.9261.00
122_I125_I0.9241.00
74_G77_T0.9241.00
123_Q126_D0.9231.00
257_H294_I0.9191.00
124_T129_R0.9181.00
258_H273_A0.9181.00
41_C44_T0.9161.00
100_I291_I0.9141.00
55_S63_F0.9031.00
123_Q127_Q0.9021.00
61_V64_P0.9021.00
50_A54_I0.9021.00
247_D274_S0.9011.00
21_L68_R0.9001.00
7_I101_I0.8911.00
48_A52_G0.8861.00
78_S84_K0.8831.00
178_I203_N0.8771.00
122_I128_S0.8771.00
123_Q131_T0.8741.00
16_V288_A0.8721.00
20_L29_V0.8711.00
202_I222_I0.8691.00
32_T96_Y0.8591.00
20_L292_V0.8581.00
189_Y192_K0.8571.00
18_H22_P0.8551.00
213_G221_P0.8541.00
268_V273_A0.8521.00
147_V231_A0.8501.00
267_Y295_L0.8471.00
105_C233_I0.8421.00
258_H290_Q0.8411.00
77_T87_L0.8391.00
27_D296_Q0.8361.00
51_A54_I0.8351.00
129_R132_Y0.8321.00
140_A167_L0.8271.00
127_Q131_T0.8261.00
120_Y134_K0.8221.00
123_Q128_S0.8191.00
34_I74_G0.8181.00
146_I157_A0.8171.00
205_A216_Y0.8131.00
16_V269_V0.8101.00
74_G88_F0.8081.00
284_A288_A0.8041.00
3_K29_V0.8021.00
130_E133_Q0.8011.00
258_H291_I0.8011.00
78_S81_I0.7961.00
114_G209_K0.7941.00
16_V291_I0.7911.00
268_V272_C0.7911.00
20_L31_I0.7911.00
47_Y52_G0.7861.00
283_L287_Q0.7831.00
56_D64_P0.7781.00
101_I272_C0.7711.00
74_G78_S0.7651.00
259_N265_H0.7611.00
57_H63_F0.7581.00
6_L16_V0.7581.00
117_E120_Y0.7581.00
224_A227_I0.7561.00
15_R288_A0.7561.00
273_A287_Q0.7551.00
49_L53_T0.7531.00
259_N294_I0.7521.00
291_I294_I0.7521.00
17_L31_I0.7511.00
74_G79_I0.7511.00
99_A266_L0.7501.00
39_Y61_V0.7491.00
109_Y116_P0.7471.00
57_H60_R0.7471.00
13_N102_G0.7461.00
296_Q300_N0.7431.00
83_Q93_P0.7421.00
172_F216_Y0.7401.00
147_V229_W0.7381.00
267_Y291_I0.7381.00
253_V262_G0.7371.00
158_S162_E0.7341.00
115_A229_W0.7331.00
21_L31_I0.7321.00
86_V89_Q0.7281.00
248_A253_V0.7281.00
74_G92_E0.7261.00
123_Q129_R0.7261.00
15_R19_R0.7251.00
142_A167_L0.7221.00
101_I266_L0.7191.00
153_G173_D0.7191.00
161_R197_H0.7191.00
55_S60_R0.7161.00
72_Q92_E0.7161.00
187_S191_Q0.7091.00
4_L295_L0.7081.00
265_H298_R0.7021.00
286_A289_E0.7021.00
9_G33_L0.6991.00
125_I132_Y0.6981.00
259_N267_Y0.6971.00
145_A227_I0.6961.00
76_I84_K0.6961.00
173_D176_N0.6951.00
172_F202_I0.6951.00
177_L184_E0.6941.00
40_H43_K0.6901.00
121_S127_Q0.6891.00
48_A53_T0.6881.00
17_L69_L0.6871.00
186_L189_Y0.6871.00
143_T224_A0.6841.00
147_V207_I0.6791.00
88_F91_R0.6771.00
109_Y115_A0.6761.00
259_N298_R0.6751.00
190_V194_F0.6721.00
129_R133_Q0.6711.00
297_K301_G0.6711.00
217_N220_D0.6691.00
34_I96_Y0.6691.00
83_Q95_S0.6681.00
20_L295_L0.6671.00
184_E187_S0.6671.00
84_K88_F0.6641.00
238_V242_L0.6621.00
177_L191_Q0.6611.00
98_D299_W0.6571.00
76_I86_V0.6571.00
156_L159_E0.6571.00
34_I88_F0.6561.00
70_D73_Y0.6561.00
239_V242_L0.6531.00
42_L45_E0.6531.00
187_S190_V0.6521.00
16_V292_V0.6511.00
215_V219_D0.6491.00
130_E134_K0.6471.00
161_R198_G0.6451.00
46_Y49_L0.6391.00
110_H229_W0.6381.00
13_N17_L0.6381.00
34_I76_I0.6361.00
246_K253_V0.6351.00
15_R285_E0.6331.00
158_S197_H0.6331.00
240_R246_K0.6331.00
109_Y229_W0.6281.00
293_Q297_K0.6281.00
47_Y50_A0.6271.00
289_E293_Q0.6261.00
112_V115_A0.6251.00
242_L246_K0.6251.00
156_L230_T0.6231.00
46_Y50_A0.6221.00
58_H63_F0.6171.00
173_D180_S0.6161.00
281_A284_A0.6141.00
249_Q274_S0.6131.00
157_A199_V0.6031.00
243_D246_K0.6021.00
244_V252_I0.6021.00
103_L238_V0.6001.00
246_K252_I0.5991.00
293_Q298_R0.5961.00
15_R18_H0.5941.00
200_R220_D0.5931.00
3_K94_I0.5911.00
29_V295_L0.5891.00
29_V97_D0.5881.00
76_I80_D0.5861.00
194_F201_I0.5831.00
146_I153_G0.5791.00
38_P73_Y0.5781.00
80_D84_K0.5741.00
86_V91_R0.5731.00
108_K111_N0.5711.00
149_A178_I0.5701.00
271_D284_A0.5691.00
282_Q285_E0.5691.00
122_I127_Q0.5681.00
37_N47_Y0.5671.00
126_D132_Y0.5611.00
44_T48_A0.5611.00
172_F205_A0.5611.00
12_G102_G0.5601.00
286_A290_Q0.5581.00
6_L102_G0.5571.00
110_H115_A0.5541.00
131_T134_K0.5531.00
101_I238_V0.5531.00
125_I130_E0.5531.00
142_A226_A0.5521.00
191_Q201_I0.5491.00
251_R279_P0.5491.00
259_N263_D0.5491.00
121_S124_T0.5481.00
157_A169_I0.5481.00
200_R203_N0.5481.00
78_S99_A0.5471.00
131_T226_A0.5451.00
46_Y52_G0.5411.00
122_I130_E0.5401.00
261_P268_V0.5391.00
35_D73_Y0.5391.00
122_I131_T0.5391.00
47_Y51_A0.5381.00
122_I129_R0.5381.00
200_R222_I0.5381.00
40_H71_V0.5381.00
109_Y121_S0.5371.00
154_V194_F0.5351.00
125_I131_T0.5331.00
9_G40_H0.5331.00
248_A251_R0.5321.00
282_Q286_A0.5301.00
285_E289_E0.5291.00
190_V193_W0.5291.00
15_R289_E0.5281.00
3_K96_Y0.5261.00
153_G230_T0.5241.00
18_H67_P0.5231.00
145_A170_I0.5231.00
57_H64_P0.5201.00
274_S287_Q0.5201.00
19_R292_V0.5191.00
253_V261_P0.5161.00
247_D250_G0.5161.00
175_G180_S0.5161.00
5_V84_K0.5141.00
139_S142_A0.5131.00
58_H65_E0.5121.00
212_E223_S0.5121.00
156_L228_V0.5121.00
294_I297_K0.5111.00
12_G100_I0.5101.00
127_Q132_Y0.5101.00
134_K226_A0.5101.00
44_T47_Y0.5091.00
39_Y60_R0.5071.00
269_V288_A0.5071.00
113_P116_P0.5061.00
96_Y265_H0.5061.00
6_L31_I0.5061.00
159_E162_E0.5061.00
48_A54_I0.5051.00
280_S283_L0.5041.00
244_V262_G0.5031.00
79_I84_K0.5021.00
171_L201_I0.5001.00
258_H294_I0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4g6hA 2 0.9887 100 0.262 Contact Map
4nwzA 2 0.9775 100 0.278 Contact Map
3h8lA 2 0.8789 100 0.344 Contact Map
3l8kA 3 0.9465 100 0.345 Contact Map
1ojtA 2 0.9493 100 0.345 Contact Map
3ntdA 2 0.9803 100 0.35 Contact Map
3sx6A 2 0.9915 100 0.351 Contact Map
2yquA 2 0.9493 100 0.352 Contact Map
3kljA 1 0.9352 100 0.352 Contact Map
3icsA 2 0.9831 100 0.352 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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