GREMLIN Database
YUID - Uncharacterized membrane protein YuiD
UniProt: O32107 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 158 (141)
Sequences: 863 (570)
Seq/√Len: 48.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
57_S78_A4.5981.00
92_A132_L4.0301.00
38_L41_S3.1411.00
57_S74_S3.0231.00
42_T83_F2.9751.00
61_A66_L2.8001.00
11_S55_A2.7621.00
70_L73_V2.7351.00
100_N130_E2.7321.00
82_M143_G2.6271.00
64_H69_S2.5441.00
18_F145_T2.1281.00
45_M141_F2.1131.00
42_T132_L2.0201.00
90_R94_E1.9530.99
12_S55_A1.8720.99
50_S54_T1.8690.99
11_S153_L1.8030.99
54_T143_G1.7930.99
15_A55_A1.7480.99
95_Q99_I1.7170.98
88_V132_L1.7120.98
50_S144_L1.6990.98
64_H70_L1.5440.97
62_L154_A1.5410.97
22_I26_I1.5050.96
58_T147_I1.4940.96
91_H132_L1.4930.96
142_G146_G1.4730.96
82_M139_V1.4710.96
60_V69_S1.4600.95
73_V77_F1.4580.95
22_I145_T1.4200.95
16_I52_A1.3820.94
57_S75_A1.3460.93
22_I141_F1.3450.93
90_R138_E1.2850.91
60_V73_V1.2690.91
7_F150_T1.2670.91
17_I81_T1.2450.90
27_Q35_D1.2190.89
53_V77_F1.2130.89
16_I25_P1.2070.88
104_I127_K1.2020.88
85_A143_G1.1900.88
135_Q138_E1.1820.87
10_L15_A1.1660.87
96_A100_N1.1570.86
100_N128_L1.1540.86
88_V95_Q1.1520.86
16_I41_S1.1500.86
53_V78_A1.1400.85
50_S82_M1.1190.84
17_I153_L1.1090.84
14_A33_K1.0920.83
55_A59_G1.0900.83
56_L77_F1.0850.82
91_H135_Q1.0840.82
50_S141_F1.0800.82
52_A76_I1.0780.82
96_A128_L1.0680.81
73_V137_I1.0610.81
90_R93_G1.0490.80
43_G49_H1.0490.80
86_T136_P1.0390.80
91_H96_A1.0380.79
34_L91_H1.0340.79
19_A42_T1.0330.79
60_V68_S1.0280.79
57_S71_F1.0170.78
107_N138_E1.0130.78
95_Q98_V1.0090.77
78_A81_T1.0010.77
90_R135_Q0.9940.76
10_L14_A0.9890.76
61_A71_F0.9850.76
87_G96_A0.9750.75
42_T48_S0.9650.74
14_A17_I0.9560.74
20_Q48_S0.9480.73
15_A51_A0.9370.72
24_V38_L0.9310.72
45_M137_I0.9250.71
5_T10_L0.9200.71
75_A79_V0.9170.70
56_L73_V0.9110.70
63_E66_L0.9070.70
12_S59_G0.9050.69
77_F99_I0.8940.68
80_I124_K0.8910.68
60_V74_S0.8850.68
99_I103_V0.8800.67
53_V56_L0.8800.67
42_T88_V0.8740.67
98_V103_V0.8740.67
15_A19_A0.8640.66
11_S59_G0.8580.65
92_A96_A0.8430.64
27_Q31_S0.8430.64
120_A123_E0.8360.63
12_S56_L0.8310.63
15_A80_I0.8300.63
21_V39_V0.8280.62
24_V41_S0.8280.62
126_K129_K0.8200.62
87_G92_A0.8190.62
87_G100_N0.8160.61
51_A102_L0.8070.60
58_T80_I0.8050.60
61_A67_D0.8030.60
94_E97_T0.8030.60
46_P49_H0.7970.59
29_I144_L0.7880.59
20_Q23_K0.7820.58
59_G150_T0.7680.57
12_S53_V0.7660.56
60_V70_L0.7440.54
66_L150_T0.7390.54
94_E138_E0.7380.54
45_M51_A0.7350.53
25_P108_R0.7340.53
38_L42_T0.7330.53
38_L48_S0.7300.53
7_F11_S0.7280.53
48_S56_L0.7190.52
98_V128_L0.7190.52
33_K129_K0.7140.51
23_K46_P0.7110.51
13_L79_V0.7070.51
54_T137_I0.6970.50
15_A27_Q0.6960.49
19_A48_S0.6870.49
20_Q129_K0.6850.48
43_G46_P0.6840.48
60_V64_H0.6820.48
74_S81_T0.6810.48
9_L12_S0.6790.48
105_D127_K0.6740.47
8_P129_K0.6710.47
5_T73_V0.6670.47
17_I36_W0.6660.46
21_V151_L0.6590.46
13_L18_F0.6520.45
92_A130_E0.6510.45
126_K149_L0.6500.45
14_A51_A0.6420.44
17_I21_V0.6390.44
109_F123_E0.6350.43
29_I138_E0.6310.43
54_T78_A0.6270.43
8_P16_I0.6250.42
14_A18_F0.6230.42
16_I95_Q0.6220.42
25_P154_A0.6220.42
85_A93_G0.6200.42
88_V140_F0.6150.41
28_F33_K0.6130.41
23_K49_H0.6060.41
7_F59_G0.6030.40
45_M132_L0.6020.40
4_L10_L0.6010.40
62_L66_L0.6000.40
87_G90_R0.6000.40
54_T64_H0.5990.40
96_A131_L0.5920.39
148_L151_L0.5900.39
18_F132_L0.5890.39
58_T62_L0.5870.39
33_K36_W0.5860.39
83_F132_L0.5840.38
91_H97_T0.5830.38
30_V61_A0.5690.37
25_P29_I0.5630.36
19_A145_T0.5630.36
36_W122_K0.5620.36
95_Q128_L0.5610.36
11_S15_A0.5590.36
10_L152_V0.5570.36
48_S51_A0.5550.36
67_D140_F0.5540.36
71_F92_A0.5470.35
74_S78_A0.5460.35
17_I152_V0.5420.34
77_F81_T0.5400.34
53_V57_S0.5400.34
14_A21_V0.5390.34
82_M145_T0.5360.34
105_D138_E0.5340.34
20_Q142_G0.5340.34
58_T150_T0.5310.34
94_E124_K0.5280.33
90_R130_E0.5260.33
25_P40_T0.5260.33
69_S74_S0.5220.33
82_M85_A0.5220.33
14_A153_L0.5220.33
78_A82_M0.5210.33
80_I105_D0.5210.33
75_A80_I0.5210.33
50_S126_K0.5180.32
24_V88_V0.5170.32
62_L151_L0.5150.32
106_F120_A0.5120.32
28_F34_L0.5110.32
86_T131_L0.5090.32
24_V68_S0.5080.31
21_V88_V0.5080.31
122_K148_L0.5070.31
54_T73_V0.5050.31
16_I80_I0.5030.31
28_F129_K0.5010.31
21_V153_L0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4px7A 1 0.7089 95.6 0.895 Contact Map
4citA 1 0.8101 95 0.899 Contact Map
2ipbA 2 0.7025 94.3 0.902 Contact Map
1d2tA 5 0.7025 93.1 0.907 Contact Map
3w36A 2 0.8734 87.2 0.918 Contact Map
1qi9A 2 0.8418 86.1 0.92 Contact Map
3bb0A 1 0.8797 80.8 0.925 Contact Map
1up8A 9 0.8354 75.3 0.928 Contact Map
2jlnA 1 0.6646 14.7 0.953 Contact Map
4tl1A 2 0.2025 9 0.958 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0062 seconds.