AMPA - BACSU - GREMLIN Contacts

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AMPA - Probable cytosol aminopeptidase

UniProt:	O32106	Sequences: MFYAVQQSEHTETLVVGLFQKSQLTGKALEIDEMLEGHLTQLLKEGDVSAKPNQVSKVFPPSSAGMKRIYFVGLGREANYSFEQAKERFAHVFQAIHKDRKQETAVLLDTFISEDVPPADAAHALAESCLLASYEVQDYKHKSNEPDKQIEAVYVVTDEDTQEVQAGLRVGQAYGQGTNSARTLVNMPGNMLTATDLASYAEELAAKYDFECEILEKSEMEELGMGGILAVNQGSTEPPKMIVLKYQGKKEWEDVVGLVGKGITFDTGGYSIKTKSGIVGMKSDMGGAAAVLGAMETIGELRPEQNVLCVIPSTDNMISGGAMKPDDVIVSLSGKTIEILNTDAEGRLVLADGITYAKQHGASVLVDVATLTGGVVVALGTETTGAMTNDQSFYQQVADAAQECGEAIWQLPITEKDKKRVKSSQMADLSNSPGREGHAIMAGTFLGEFAESTPWVHLDIAGTATANKATCFGPAGATGVMARTLATLAERFTLEEDKNE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	500 (452)
Sequences:	3858 (2733)
Seq/√Len:	128.5

ECOLI - AMPA PEPB
BACSU - AMPA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
331_S	337_I	3.451	1.00
216_E	219_E	3.223	1.00
227_G	337_I	3.125	1.00
391_Q	410_Q	3.067	1.00
312_P	353_G	3.000	1.00
387_M	439_A	2.899	1.00
185_V	286_G	2.835	1.00
263_I	314_T	2.803	1.00
201_A	292_L	2.764	1.00
298_I	303_P	2.760	1.00
236_T	321_G	2.705	1.00
312_P	349_V	2.650	1.00
232_N	239_P	2.610	1.00
375_V	385_G	2.534	1.00
170_V	490_E	2.528	1.00
419_K	422_K	2.504	1.00
197_L	288_A	2.501	1.00
213_E	245_K	2.475	1.00
310_V	357_A	2.450	1.00
298_I	307_V	2.406	1.00
387_M	443_G	2.371	1.00
242_I	313_S	2.363	1.00
193_T	237_E	2.288	1.00
256_V	489_A	2.286	1.00
354_I	446_L	2.277	1.00
211_E	245_K	2.257	1.00
384_T	480_V	2.250	1.00
383_T	414_T	2.228	1.00
230_A	323_M	2.192	1.00
176_Q	300_E	2.175	1.00
230_A	329_I	2.166	1.00
267_T	317_M	2.122	1.00
263_I	349_V	2.100	1.00
340_L	432_S	2.085	1.00
270_Y	318_I	2.068	1.00
200_Y	203_E	2.055	1.00
335_K	448_E	2.049	1.00
487_T	491_R	2.005	1.00
418_K	448_E	1.986	1.00
388_T	394_Y	1.965	1.00
332_L	355_T	1.946	1.00
227_G	331_S	1.946	1.00
219_E	222_E	1.916	1.00
397_V	456_V	1.912	1.00
197_L	313_S	1.910	1.00
32_D	37_G	1.901	1.00
394_Y	410_Q	1.900	1.00
248_G	306_N	1.886	1.00
328_V	426_M	1.869	1.00
216_E	240_K	1.837	1.00
232_N	314_T	1.794	1.00
177_G	293_G	1.788	1.00
425_Q	475_A	1.787	1.00
296_E	300_E	1.780	1.00
330_V	336_T	1.777	1.00
377_V	435_R	1.776	1.00
220_M	241_M	1.766	1.00
368_V	485_L	1.758	1.00
205_A	212_C	1.733	1.00
384_T	463_T	1.709	1.00
195_T	237_E	1.700	1.00
340_L	430_S	1.684	1.00
292_L	311_I	1.682	1.00
173_A	177_G	1.677	1.00
193_T	196_D	1.676	1.00
93_F	129_C	1.675	1.00
411_L	439_A	1.673	1.00
301_L	486_A	1.663	1.00
387_M	411_L	1.660	1.00
272_I	275_K	1.658	1.00
258_L	291_V	1.647	1.00
216_E	238_P	1.635	1.00
257_G	357_A	1.631	1.00
217_K	221_E	1.601	1.00
398_A	408_I	1.591	1.00
96_I	104_T	1.582	1.00
374_G	438_H	1.569	1.00
376_V	436_E	1.564	1.00
192_L	196_D	1.562	1.00
390_D	454_P	1.558	1.00
386_A	458_L	1.545	1.00
323_M	329_I	1.539	1.00
217_K	239_P	1.531	1.00
207_K	296_E	1.530	1.00
375_V	411_L	1.530	1.00
241_M	353_G	1.499	1.00
397_V	488_L	1.496	1.00
233_Q	323_M	1.491	1.00
245_K	360_H	1.485	1.00
183_T	186_N	1.482	1.00
123_H	170_V	1.482	1.00
384_T	458_L	1.480	1.00
177_G	297_T	1.479	1.00
134_Y	183_T	1.478	1.00
367_D	455_W	1.474	1.00
167_G	171_G	1.472	1.00
295_M	309_C	1.467	1.00
424_S	427_A	1.466	1.00
195_T	240_K	1.464	1.00
403_E	487_T	1.463	1.00
258_L	294_A	1.463	1.00
295_M	298_I	1.457	1.00
226_G	330_V	1.456	1.00
221_E	233_Q	1.443	1.00
398_A	410_Q	1.433	1.00
255_V	308_L	1.429	1.00
129_C	153_V	1.429	1.00
329_I	339_I	1.429	1.00
400_A	487_T	1.427	1.00
429_L	448_E	1.426	1.00
375_V	439_A	1.423	1.00
217_K	238_P	1.421	1.00
298_I	489_A	1.413	1.00
57_K	70_Y	1.413	1.00
236_T	319_S	1.408	1.00
171_G	175_G	1.395	1.00
364_V	488_L	1.381	1.00
50_A	73_G	1.379	1.00
279_V	340_L	1.373	1.00
335_K	429_L	1.371	1.00
217_K	232_N	1.371	1.00
245_K	306_N	1.368	1.00
395_Q	398_A	1.358	1.00
136_V	139_Y	1.357	1.00
220_M	228_I	1.349	1.00
386_A	456_V	1.348	1.00
215_L	223_L	1.347	1.00
199_S	203_E	1.341	1.00
333_S	355_T	1.340	1.00
393_F	456_V	1.331	1.00
386_A	394_Y	1.330	1.00
291_V	309_C	1.328	1.00
205_A	244_L	1.325	1.00
249_K	306_N	1.322	1.00
256_V	364_V	1.321	1.00
391_Q	395_Q	1.315	1.00
329_I	348_L	1.312	1.00
271_S	275_K	1.311	1.00
358_K	453_T	1.310	1.00
194_A	264_T	1.307	1.00
332_L	359_Q	1.305	1.00
297_T	486_A	1.304	1.00
487_T	490_E	1.303	1.00
310_V	353_G	1.291	1.00
225_M	356_Y	1.288	1.00
139_Y	187_M	1.280	1.00
189_G	326_D	1.276	1.00
165_Q	169_R	1.271	1.00
309_C	368_V	1.267	1.00
255_V	306_N	1.263	1.00
254_D	363_S	1.257	1.00
242_I	311_I	1.254	1.00
208_Y	296_E	1.252	1.00
225_M	332_L	1.249	1.00
283_S	465_T	1.244	1.00
244_L	295_M	1.244	1.00
417_D	437_G	1.236	1.00
217_K	240_K	1.233	1.00
198_A	242_I	1.227	1.00
263_I	312_P	1.225	1.00
381_T	436_E	1.224	1.00
199_S	202_E	1.223	1.00
81_S	84_Q	1.220	0.99
382_E	416_K	1.218	0.99
294_A	298_I	1.217	0.99
130_L	175_G	1.215	0.99
169_R	172_Q	1.215	0.99
249_K	252_W	1.209	0.99
227_G	351_A	1.207	0.99
196_D	199_S	1.203	0.99
247_Q	306_N	1.203	0.99
97_H	135_E	1.202	0.99
197_L	242_I	1.200	0.99
139_Y	191_M	1.198	0.99
257_G	362_A	1.196	0.99
210_F	295_M	1.193	0.99
233_Q	321_G	1.189	0.99
212_C	244_L	1.189	0.99
383_T	407_A	1.187	0.99
413_I	443_G	1.187	0.99
384_T	481_M	1.183	0.99
430_S	433_P	1.176	0.99
257_G	310_V	1.176	0.99
255_V	363_S	1.168	0.99
368_V	481_M	1.161	0.99
228_I	314_T	1.160	0.99
83_E	472_F	1.157	0.99
271_S	278_I	1.155	0.99
408_I	484_T	1.150	0.99
285_M	289_A	1.146	0.99
395_Q	399_D	1.144	0.99
243_V	356_Y	1.136	0.99
291_V	368_V	1.135	0.99
123_H	127_E	1.133	0.99
76_R	79_N	1.131	0.99
288_A	311_I	1.129	0.99
364_V	454_P	1.129	0.99
122_A	167_G	1.127	0.99
227_G	329_I	1.124	0.99
51_K	54_Q	1.122	0.99
358_K	450_A	1.122	0.99
237_E	324_K	1.121	0.99
358_K	452_S	1.118	0.99
220_M	225_M	1.116	0.99
398_A	402_Q	1.111	0.99
194_A	315_D	1.111	0.99
122_A	126_A	1.111	0.99
323_M	339_I	1.108	0.99
211_E	247_Q	1.105	0.99
218_S	221_E	1.105	0.99
377_V	436_E	1.103	0.99
365_L	453_T	1.101	0.99
418_K	422_K	1.099	0.99
354_I	450_A	1.097	0.99
361_G	453_T	1.089	0.99
331_S	355_T	1.089	0.99
396_Q	488_L	1.088	0.99
323_M	348_L	1.088	0.99
262_G	288_A	1.088	0.99
193_T	324_K	1.087	0.99
274_T	377_V	1.080	0.99
294_A	485_L	1.078	0.99
376_V	439_A	1.077	0.99
181_A	293_G	1.077	0.99
366_V	488_L	1.075	0.99
139_Y	328_V	1.074	0.99
407_A	414_T	1.074	0.99
134_Y	186_N	1.073	0.99
210_F	299_G	1.073	0.99
48_V	56_S	1.062	0.99
209_D	302_R	1.060	0.99
198_A	214_I	1.058	0.99
136_V	183_T	1.057	0.99
228_I	241_M	1.057	0.99
257_G	365_L	1.054	0.99
365_L	450_A	1.053	0.99
246_Y	302_R	1.049	0.98
173_A	301_L	1.047	0.98
215_L	243_V	1.047	0.98
181_A	290_A	1.042	0.98
376_V	462_G	1.041	0.98
32_D	40_T	1.041	0.98
194_A	232_N	1.039	0.98
224_G	332_L	1.038	0.98
393_F	488_L	1.035	0.98
219_E	223_L	1.035	0.98
138_D	187_M	1.034	0.98
213_E	243_V	1.034	0.98
413_I	444_T	1.033	0.98
376_V	381_T	1.032	0.98
215_L	219_E	1.028	0.98
229_L	233_Q	1.026	0.98
196_D	200_Y	1.025	0.98
290_A	294_A	1.021	0.98
86_K	127_E	1.019	0.98
178_T	483_R	1.017	0.98
236_T	320_G	1.012	0.98
89_F	125_L	1.011	0.98
205_A	210_F	1.009	0.98
223_L	332_L	1.008	0.98
314_T	349_V	1.004	0.98
232_N	315_D	1.003	0.98
89_F	128_S	1.003	0.98
198_A	240_K	1.002	0.98
128_S	132_A	0.999	0.98
187_M	191_M	0.998	0.98
354_I	365_L	0.998	0.98
184_L	285_M	0.990	0.98
389_N	447_G	0.989	0.98
204_L	296_E	0.983	0.98
403_E	491_R	0.982	0.98
197_L	292_L	0.982	0.98
444_T	447_G	0.980	0.98
440_I	444_T	0.975	0.98
258_L	489_A	0.975	0.98
357_A	365_L	0.974	0.98
364_V	393_F	0.973	0.97
234_G	318_I	0.972	0.97
384_T	408_I	0.971	0.97
217_K	229_L	0.968	0.97
243_V	308_L	0.968	0.97
89_F	92_V	0.966	0.97
375_V	463_T	0.961	0.97
418_K	444_T	0.954	0.97
276_S	435_R	0.953	0.97
50_A	54_Q	0.945	0.97
245_K	308_L	0.943	0.97
220_M	332_L	0.941	0.97
243_V	310_V	0.941	0.97
303_P	490_E	0.935	0.97
86_K	90_A	0.934	0.97
201_A	242_I	0.933	0.97
417_D	440_I	0.932	0.97
202_E	206_A	0.931	0.97
198_A	212_C	0.928	0.97
220_M	229_L	0.925	0.97
185_V	477_A	0.920	0.96
356_Y	360_H	0.918	0.96
180_S	204_L	0.917	0.96
290_A	482_A	0.915	0.96
228_I	232_N	0.915	0.96
103_E	152_A	0.911	0.96
366_V	489_A	0.905	0.96
47_D	68_R	0.904	0.96
318_I	322_A	0.898	0.96
85_A	121_A	0.893	0.96
202_E	212_C	0.892	0.96
89_F	93_F	0.891	0.96
172_Q	176_Q	0.890	0.96
221_E	229_L	0.889	0.96
85_A	125_L	0.887	0.96
283_S	464_A	0.883	0.96
195_T	199_S	0.880	0.95
197_L	311_I	0.876	0.95
397_V	408_I	0.873	0.95
421_V	432_S	0.868	0.95
257_G	360_H	0.868	0.95
244_L	292_L	0.862	0.95
348_L	431_N	0.862	0.95
368_V	458_L	0.861	0.95
214_I	242_I	0.860	0.95
358_K	451_E	0.860	0.95
213_E	219_E	0.858	0.95
438_H	441_M	0.857	0.95
40_T	44_K	0.852	0.95
220_M	240_K	0.850	0.95
401_A	484_T	0.849	0.95
386_A	398_A	0.848	0.94
366_V	485_L	0.846	0.94
243_V	360_H	0.846	0.94
407_A	416_K	0.846	0.94
479_G	482_A	0.842	0.94
48_V	73_G	0.841	0.94
196_D	237_E	0.840	0.94
418_K	447_G	0.836	0.94
131_L	175_G	0.833	0.94
429_L	449_F	0.828	0.94
215_L	356_Y	0.825	0.94
331_S	445_F	0.825	0.94
126_A	171_G	0.825	0.94
341_N	438_H	0.824	0.94
399_D	403_E	0.824	0.94
420_R	433_P	0.823	0.94
203_E	207_K	0.823	0.94
258_L	307_V	0.823	0.94
337_I	429_L	0.820	0.93
191_M	196_D	0.820	0.93
374_G	377_V	0.819	0.93
124_A	127_E	0.818	0.93
94_Q	132_A	0.816	0.93
234_G	319_S	0.816	0.93
254_D	361_G	0.815	0.93
136_V	187_M	0.814	0.93
422_K	448_E	0.811	0.93
389_N	450_A	0.811	0.93
481_M	484_T	0.809	0.93
397_V	484_T	0.809	0.93
92_V	125_L	0.808	0.93
399_D	491_R	0.807	0.93
127_E	483_R	0.807	0.93
187_M	192_L	0.806	0.93
83_E	87_E	0.805	0.93
130_L	172_Q	0.804	0.93
218_S	222_E	0.802	0.93
274_T	277_G	0.802	0.93
241_M	310_V	0.800	0.93
295_M	299_G	0.798	0.92
308_L	360_H	0.797	0.92
310_V	356_Y	0.796	0.92
198_A	202_E	0.795	0.92
396_Q	491_R	0.795	0.92
437_G	440_I	0.794	0.92
259_V	365_L	0.791	0.92
305_Q	489_A	0.790	0.92
217_K	314_T	0.790	0.92
271_S	274_T	0.789	0.92
294_A	489_A	0.788	0.92
211_E	222_E	0.788	0.92
418_K	429_L	0.788	0.92
286_G	290_A	0.788	0.92
349_V	353_G	0.787	0.92
88_R	92_V	0.785	0.92
341_N	432_S	0.784	0.92
74_L	88_R	0.784	0.92
486_A	490_E	0.783	0.92
310_V	360_H	0.780	0.92
228_I	349_V	0.771	0.91
192_L	197_L	0.770	0.91
180_S	296_E	0.770	0.91
271_S	340_L	0.770	0.91
276_S	279_V	0.770	0.91
283_S	477_A	0.770	0.91
270_Y	277_G	0.768	0.91
220_M	314_T	0.767	0.91
317_M	324_K	0.765	0.91
32_D	35_L	0.764	0.91
294_A	309_C	0.764	0.91
257_G	308_L	0.760	0.91
282_K	426_M	0.760	0.91
313_S	349_V	0.758	0.90
270_Y	279_V	0.757	0.90
227_G	339_I	0.754	0.90
55_V	70_Y	0.754	0.90
420_R	441_M	0.754	0.90
250_K	306_N	0.753	0.90
283_S	286_G	0.752	0.90
400_A	404_C	0.750	0.90
49_S	54_Q	0.747	0.90
179_N	183_T	0.741	0.89
248_G	251_E	0.736	0.89
270_Y	280_G	0.734	0.89
414_T	417_D	0.732	0.89
131_L	483_R	0.728	0.89
204_L	210_F	0.727	0.89
241_M	312_P	0.727	0.89
290_A	368_V	0.725	0.88
415_E	447_G	0.724	0.88
275_K	278_I	0.723	0.88
126_A	168_L	0.721	0.88
208_Y	300_E	0.718	0.88
181_A	289_A	0.717	0.88
377_V	439_A	0.716	0.88
72_V	92_V	0.715	0.88
404_C	407_A	0.714	0.88
204_L	292_L	0.712	0.87
406_E	480_V	0.711	0.87
450_A	453_T	0.711	0.87
173_A	300_E	0.710	0.87
339_I	432_S	0.709	0.87
299_G	303_P	0.708	0.87
279_V	326_D	0.704	0.87
421_V	429_L	0.704	0.87
128_S	131_L	0.703	0.87
303_P	489_A	0.702	0.87
181_A	482_A	0.702	0.87
388_T	410_Q	0.701	0.87
442_A	446_L	0.700	0.87
375_V	378_A	0.696	0.86
387_M	440_I	0.694	0.86
130_L	179_N	0.693	0.86
420_R	434_G	0.692	0.86
331_S	335_K	0.691	0.86
263_I	353_G	0.691	0.86
194_A	314_T	0.690	0.86
280_G	467_N	0.690	0.86
202_E	214_I	0.689	0.86
444_T	448_E	0.689	0.86
398_A	401_A	0.689	0.86
55_V	72_V	0.689	0.86
387_M	413_I	0.687	0.86
469_A	474_P	0.685	0.85
228_I	239_P	0.684	0.85
315_D	324_K	0.684	0.85
104_T	153_V	0.684	0.85
43_L	71_F	0.682	0.85
417_D	444_T	0.682	0.85
331_S	351_A	0.680	0.85
391_Q	394_Y	0.680	0.85
386_A	408_I	0.679	0.85
180_S	200_Y	0.679	0.85
392_S	396_Q	0.678	0.85
124_A	128_S	0.677	0.85
288_A	313_S	0.675	0.85
286_G	464_A	0.674	0.84
83_E	86_K	0.673	0.84
203_E	206_A	0.673	0.84
197_L	201_A	0.672	0.84
131_L	182_R	0.671	0.84
413_I	455_W	0.668	0.84
329_I	337_I	0.665	0.84
95_A	98_K	0.664	0.84
34_M	37_G	0.664	0.84
92_V	129_C	0.661	0.83
186_N	477_A	0.661	0.83
411_L	440_I	0.660	0.83
174_Y	486_A	0.659	0.83
177_G	180_S	0.657	0.83
480_V	484_T	0.656	0.83
433_P	441_M	0.656	0.83
274_T	278_I	0.656	0.83
248_G	304_E	0.654	0.83
271_S	279_V	0.652	0.82
253_E	306_N	0.651	0.82
187_M	196_D	0.650	0.82
341_N	374_G	0.649	0.82
294_A	486_A	0.647	0.82
176_Q	296_E	0.647	0.82
208_Y	299_G	0.647	0.82
255_V	362_A	0.644	0.82
53_N	91_H	0.641	0.81
275_K	279_V	0.640	0.81
339_I	342_T	0.640	0.81
126_A	175_G	0.639	0.81
102_Q	151_E	0.639	0.81
374_G	442_A	0.639	0.81
85_A	89_F	0.639	0.81
105_A	156_V	0.633	0.81
401_A	404_C	0.633	0.81
177_G	181_A	0.632	0.81
157_T	164_V	0.629	0.80
241_M	349_V	0.628	0.80
375_V	387_M	0.627	0.80
206_A	209_D	0.627	0.80
127_E	171_G	0.626	0.80
56_S	71_F	0.626	0.80
421_V	424_S	0.626	0.80
397_V	485_L	0.623	0.80
406_E	484_T	0.622	0.79
170_V	174_Y	0.621	0.79
413_I	447_G	0.621	0.79
272_I	318_I	0.619	0.79
286_G	477_A	0.617	0.79
31_I	35_L	0.617	0.79
256_V	488_L	0.617	0.79
263_I	267_T	0.616	0.79
275_K	432_S	0.615	0.79
234_G	322_A	0.615	0.79
47_D	59_F	0.614	0.79
80_Y	85_A	0.614	0.79
57_K	68_R	0.612	0.78
182_R	474_P	0.611	0.78
394_Y	398_A	0.610	0.78
339_I	431_N	0.610	0.78
206_A	222_E	0.607	0.78
244_L	311_I	0.606	0.78
138_D	183_T	0.605	0.78
117_P	120_D	0.605	0.78
74_L	77_E	0.601	0.77
280_G	283_S	0.600	0.77
415_E	419_K	0.600	0.77
50_A	75_G	0.600	0.77
38_H	41_Q	0.600	0.77
356_Y	359_Q	0.599	0.77
355_T	358_K	0.599	0.77
332_L	356_Y	0.596	0.77
87_E	91_H	0.594	0.76
270_Y	326_D	0.594	0.76
177_G	296_E	0.593	0.76
180_S	292_L	0.593	0.76
389_N	455_W	0.593	0.76
230_A	233_Q	0.592	0.76
466_A	469_A	0.591	0.76
137_Q	141_H	0.590	0.76
31_I	36_E	0.589	0.76
212_C	242_I	0.587	0.75
274_T	435_R	0.587	0.75
344_A	373_G	0.586	0.75
270_Y	317_M	0.585	0.75
64_A	69_I	0.583	0.75
93_F	128_S	0.583	0.75
173_A	297_T	0.582	0.75
409_W	412_P	0.582	0.75
335_K	451_E	0.582	0.75
39_L	43_L	0.580	0.75
230_A	348_L	0.579	0.74
214_I	240_K	0.579	0.74
139_Y	183_T	0.576	0.74
36_E	40_T	0.575	0.74
220_M	239_P	0.575	0.74
204_L	208_Y	0.575	0.74
282_K	338_E	0.574	0.74
267_T	270_Y	0.574	0.74
388_T	391_Q	0.573	0.74
422_K	425_Q	0.573	0.74
188_P	282_K	0.571	0.73
389_N	410_Q	0.571	0.73
168_L	171_G	0.571	0.73
178_T	482_A	0.569	0.73
292_L	313_S	0.569	0.73
183_T	187_M	0.569	0.73
60_P	63_S	0.568	0.73
338_E	424_S	0.568	0.73
210_F	244_L	0.568	0.73
458_L	485_L	0.566	0.73
175_G	179_N	0.566	0.73
87_E	472_F	0.565	0.73
259_V	450_A	0.565	0.73
408_I	481_M	0.564	0.73
180_S	293_G	0.564	0.73
228_I	353_G	0.563	0.72
183_T	200_Y	0.563	0.72
271_S	326_D	0.563	0.72
357_A	360_H	0.562	0.72
123_H	174_Y	0.562	0.72
195_T	238_P	0.562	0.72
299_G	309_C	0.560	0.72
174_Y	297_T	0.559	0.72
229_L	232_N	0.559	0.72
241_M	314_T	0.558	0.72
34_M	64_A	0.558	0.72
219_E	240_K	0.558	0.72
374_G	439_A	0.557	0.72
420_R	436_E	0.557	0.72
190_N	270_Y	0.556	0.71
191_M	328_V	0.556	0.71
328_V	425_Q	0.555	0.71
251_E	254_D	0.555	0.71
104_T	150_I	0.554	0.71
137_Q	140_K	0.554	0.71
210_F	296_E	0.554	0.71
470_T	473_G	0.553	0.71
106_V	125_L	0.551	0.71
295_M	307_V	0.551	0.71
401_A	407_A	0.547	0.70
93_F	133_S	0.546	0.70
220_M	349_V	0.546	0.70
337_I	445_F	0.545	0.70
404_C	487_T	0.543	0.70
251_E	306_N	0.542	0.70
222_E	250_K	0.542	0.70
41_Q	60_P	0.542	0.70
379_L	411_L	0.541	0.69
383_T	417_D	0.541	0.69
137_Q	143_S	0.540	0.69
424_S	429_L	0.540	0.69
187_M	200_Y	0.540	0.69
91_H	95_A	0.540	0.69
414_T	444_T	0.538	0.69
249_K	255_V	0.538	0.69
180_S	477_A	0.538	0.69
408_I	480_V	0.537	0.69
131_L	178_T	0.536	0.69
401_A	408_I	0.536	0.69
271_S	318_I	0.536	0.69
421_V	444_T	0.535	0.69
291_V	485_L	0.533	0.68
236_T	272_I	0.530	0.68
279_V	432_S	0.530	0.68
174_Y	178_T	0.530	0.68
417_D	470_T	0.530	0.68
72_V	91_H	0.529	0.68
35_L	38_H	0.528	0.68
337_I	351_A	0.528	0.68
433_P	438_H	0.527	0.67
220_M	232_N	0.527	0.67
141_H	335_K	0.527	0.67
234_G	321_G	0.525	0.67
170_V	486_A	0.525	0.67
46_G	56_S	0.525	0.67
234_G	317_M	0.524	0.67
417_D	441_M	0.524	0.67
358_K	365_L	0.522	0.67
97_H	100_R	0.522	0.67
221_E	226_G	0.521	0.67
226_G	230_A	0.521	0.67
257_G	453_T	0.520	0.66
79_N	84_Q	0.519	0.66
122_A	164_V	0.518	0.66
392_S	395_Q	0.517	0.66
205_A	208_Y	0.516	0.66
271_S	325_P	0.516	0.66
369_A	455_W	0.515	0.66
237_E	314_T	0.513	0.65
404_C	484_T	0.512	0.65
226_G	339_I	0.512	0.65
201_A	311_I	0.512	0.65
341_N	348_L	0.512	0.65
271_S	431_N	0.511	0.65
308_L	357_A	0.510	0.65
395_Q	410_Q	0.509	0.65
434_G	441_M	0.509	0.65
294_A	297_T	0.508	0.65
290_A	479_G	0.508	0.65
177_G	300_E	0.508	0.65
265_F	275_K	0.508	0.65
355_T	451_E	0.506	0.64
254_D	364_V	0.505	0.64
249_K	253_E	0.505	0.64
212_C	309_C	0.505	0.64
382_E	414_T	0.504	0.64
88_R	91_H	0.504	0.64
82_F	124_A	0.504	0.64
460_I	464_A	0.502	0.64
288_A	312_P	0.502	0.64
280_G	465_T	0.501	0.64
90_A	96_I	0.501	0.64
265_F	409_W	0.500	0.63
52_P	84_Q	0.500	0.63

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1gytA	6	0.988	100	0.074	Contact Map
3h8gF	5	0.98	100	0.078	Contact Map
3jruB	5	0.966	100	0.084	Contact Map
3peiA	5	0.902	100	0.092	Contact Map
3kzwA	6	0.974	100	0.106	Contact Map
1lamA	5	0.928	100	0.11	Contact Map
4ksiA	5	0.958	100	0.113	Contact Map
3kr4A	5	0.96	100	0.132	Contact Map
3ij3A	5	0.898	100	0.164	Contact Map
4efdA	5	0.93	100	0.223	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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