PNCB - BACSU - GREMLIN Contacts

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PNCB - Nicotinate phosphoribosyltransferase

UniProt:	O32090	Sequences: MLEYGFKDDSLSLHTDLYQINMAETYWRDGIHEKKAIFELFFRRLPFENGYAVFAGLEKAIEYLENFKFTDSDLSYLQDELGYHEDFIEYLRGLSFTGSLYSMKEGELVFNNEPIMRVEAPLVEAQLIETALLNIVNYQTLIATKAARIKGVIGDEVALEFGTRRAHEMDAAMWGARAALIGGFSATSNVRAGKRFNIPVSGTHAHALVQAYRDEYTAFKKYAETHKDCVFLVDTYDTLRSGMPNAIRVAKEFGDRINFIGIRLDSGDLAYLSKKARKMLDEAGFTDAKVIASSDLDEHTIMNLKAQGARIDVWGVGTKLITAYDQPALGAVYKLVAIEEDGKMVDTIKISSNPEKVTTPGRKKVYRIINQSNHHSEGDYIALYDEQVNDQKRLRMFHPVHTFISKFVTNFYAKDLHELIFEKGILCYQNPEISDIQQYVQDNLSLLWEEYKRISKPEEYPVDLSEDCWSNKMQRIHEVKSRIEEELEEE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	490 (446)
Sequences:	1948 (1166)
Seq/√Len:	55.2

ECOLI - PNCB
BACSU - PNCB
SULSO - Q980F6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
193_G	200_V	4.931	1.00
214_D	217_T	4.850	1.00
262_I	276_A	4.539	1.00
78_Q	85_E	4.299	1.00
220_K	252_E	3.673	1.00
65_E	426_L	3.577	1.00
364_K	415_D	3.573	1.00
251_K	285_F	3.545	1.00
64_L	100_L	3.329	1.00
71_D	92_R	3.264	1.00
40_L	132_L	3.241	1.00
60_A	132_L	3.188	1.00
432_E	435_D	3.159	1.00
466_E	470_S	3.147	1.00
419_L	422_E	3.082	1.00
61_I	430_N	3.066	1.00
28_R	84_H	2.957	1.00
163_T	172_A	2.956	1.00
98_G	120_A	2.883	1.00
216_Y	220_K	2.773	1.00
233_V	276_A	2.759	1.00
120_A	125_A	2.725	1.00
233_V	243_M	2.636	1.00
71_D	75_S	2.625	1.00
233_V	262_I	2.561	1.00
186_A	201_S	2.414	1.00
103_M	109_V	2.353	1.00
275_K	278_K	2.347	1.00
233_V	279_M	2.307	1.00
73_D	194_K	2.232	1.00
89_E	92_R	2.232	1.00
291_I	313_V	2.210	1.00
70_T	73_D	2.206	1.00
305_K	314_W	2.198	1.00
51_Y	147_A	2.189	1.00
117_R	417_H	2.106	1.00
40_L	60_A	2.103	1.00
25_T	208_L	2.100	1.00
150_K	185_S	2.067	1.00
99_S	423_K	2.036	1.00
180_L	437_Q	2.015	1.00
230_V	261_G	2.000	1.00
60_A	116_M	1.984	1.00
175_G	321_I	1.982	1.00
301_I	316_V	1.976	1.00
180_L	198_I	1.958	1.00
158_A	184_F	1.958	1.00
121_P	124_E	1.939	1.00
51_Y	151_G	1.916	1.00
289_K	312_D	1.909	1.00
53_V	440_V	1.905	1.00
438_Q	442_D	1.901	1.00
431_P	439_Y	1.895	1.00
254_G	258_N	1.887	1.00
258_N	287_D	1.867	0.99
104_K	418_E	1.863	0.99
101_Y	419_L	1.862	0.99
383_L	471_N	1.835	0.99
156_E	314_W	1.809	0.99
97_T	124_E	1.798	0.99
61_I	420_I	1.797	0.99
54_F	57_L	1.796	0.99
220_K	224_E	1.794	0.99
159_L	201_S	1.792	0.99
216_Y	248_R	1.781	0.99
180_L	433_I	1.774	0.99
156_E	305_K	1.767	0.99
107_E	443_N	1.756	0.99
99_S	119_E	1.747	0.99
250_A	259_F	1.746	0.99
385_D	467_D	1.742	0.99
180_L	199_P	1.739	0.99
42_F	45_L	1.736	0.99
64_L	128_I	1.709	0.99
247_I	279_M	1.708	0.99
65_E	425_I	1.707	0.99
74_L	88_I	1.700	0.99
40_L	136_V	1.685	0.99
359_T	472_K	1.682	0.99
278_K	282_E	1.667	0.99
85_E	89_E	1.665	0.99
277_R	281_D	1.664	0.99
150_K	158_A	1.650	0.99
63_Y	131_A	1.650	0.99
276_A	279_M	1.646	0.99
24_E	84_H	1.646	0.99
89_E	93_G	1.637	0.99
167_H	171_A	1.622	0.98
273_S	292_A	1.618	0.98
119_E	362_R	1.585	0.98
157_V	185_S	1.578	0.98
109_V	115_I	1.541	0.98
304_L	309_A	1.535	0.98
98_G	124_E	1.533	0.98
23_A	67_F	1.523	0.98
90_Y	123_V	1.511	0.98
269_L	311_I	1.510	0.98
434_S	437_Q	1.478	0.97
470_S	474_Q	1.478	0.97
237_D	240_R	1.447	0.97
57_L	420_I	1.443	0.97
150_K	155_D	1.443	0.97
241_S	244_P	1.442	0.97
420_I	426_L	1.439	0.97
244_P	279_M	1.426	0.97
35_K	339_E	1.422	0.97
52_A	140_T	1.404	0.96
75_S	79_D	1.401	0.96
31_I	34_K	1.390	0.96
369_I	414_K	1.388	0.96
101_Y	119_E	1.387	0.96
421_F	426_L	1.383	0.96
103_M	365_V	1.379	0.96
238_T	264_L	1.378	0.96
285_F	288_A	1.371	0.96
80_E	200_V	1.371	0.96
35_K	119_E	1.369	0.96
101_Y	422_E	1.367	0.96
118_V	132_L	1.340	0.95
146_A	184_F	1.338	0.95
191_R	194_K	1.337	0.95
420_I	428_Y	1.337	0.95
61_I	426_L	1.315	0.95
180_L	434_S	1.313	0.95
371_Q	412_Y	1.312	0.95
254_G	287_D	1.311	0.94
386_E	465_S	1.306	0.94
253_F	256_R	1.302	0.94
149_I	158_A	1.301	0.94
67_F	94_L	1.298	0.94
418_E	428_Y	1.296	0.94
72_S	194_K	1.293	0.94
221_K	224_E	1.289	0.94
366_Y	382_A	1.286	0.94
159_L	186_A	1.283	0.94
414_K	443_N	1.268	0.93
159_L	313_V	1.264	0.93
295_D	330_G	1.264	0.93
24_E	28_R	1.259	0.93
128_I	132_L	1.258	0.93
216_Y	245_N	1.256	0.93
53_V	108_L	1.255	0.93
279_M	283_A	1.249	0.93
243_M	279_M	1.245	0.93
29_D	221_K	1.244	0.93
429_Q	435_D	1.244	0.93
453_R	457_P	1.243	0.93
223_A	249_V	1.242	0.93
438_Q	441_Q	1.242	0.93
261_G	288_A	1.241	0.93
61_I	421_F	1.239	0.93
107_E	416_L	1.229	0.92
17_L	200_V	1.221	0.92
397_F	469_W	1.219	0.92
23_A	123_V	1.216	0.92
300_T	303_N	1.207	0.92
230_V	291_I	1.205	0.92
31_I	211_A	1.201	0.91
78_Q	92_R	1.200	0.91
319_K	324_Y	1.199	0.91
297_D	319_K	1.192	0.91
414_K	446_L	1.180	0.91
220_K	253_F	1.175	0.91
393_R	409_T	1.158	0.90
76_Y	200_V	1.157	0.90
426_L	430_N	1.151	0.90
270_A	307_Q	1.151	0.90
47_F	323_A	1.150	0.90
431_P	436_I	1.150	0.90
243_M	276_A	1.148	0.89
254_G	285_F	1.141	0.89
364_K	417_H	1.139	0.89
228_D	257_I	1.139	0.89
217_T	221_K	1.132	0.89
138_Y	142_I	1.119	0.88
28_R	86_D	1.119	0.88
63_Y	67_F	1.117	0.88
174_W	196_F	1.116	0.88
94_L	124_E	1.115	0.88
216_Y	252_E	1.111	0.88
192_A	198_I	1.104	0.88
439_Y	443_N	1.102	0.87
277_R	312_D	1.096	0.87
295_D	318_T	1.093	0.87
17_L	190_V	1.089	0.87
264_L	272_L	1.088	0.87
431_P	435_D	1.086	0.87
382_A	465_S	1.080	0.86
76_Y	193_G	1.080	0.86
39_E	363_K	1.077	0.86
292_A	311_I	1.074	0.86
181_I	436_I	1.074	0.86
99_S	422_E	1.072	0.86
17_L	80_E	1.070	0.86
61_I	427_C	1.065	0.86
50_G	457_P	1.060	0.85
468_C	471_N	1.057	0.85
24_E	225_T	1.056	0.85
148_R	298_E	1.051	0.85
243_M	262_I	1.048	0.85
58_E	430_N	1.048	0.85
45_L	52_A	1.046	0.85
241_S	245_N	1.045	0.85
323_A	327_P	1.045	0.85
220_K	249_V	1.043	0.84
421_F	428_Y	1.041	0.84
131_A	135_I	1.040	0.84
54_F	103_M	1.039	0.84
242_G	246_A	1.036	0.84
36_A	122_L	1.035	0.84
212_Y	221_K	1.033	0.84
318_T	328_A	1.033	0.84
264_L	292_A	1.028	0.84
97_T	120_A	1.027	0.83
242_G	249_V	1.026	0.83
185_S	437_Q	1.017	0.83
193_G	199_P	1.017	0.83
264_L	311_I	1.015	0.83
37_I	119_E	1.014	0.83
100_L	128_I	1.008	0.82
271_Y	458_E	1.005	0.82
104_K	439_Y	1.005	0.82
251_K	254_G	1.002	0.82
58_E	62_E	0.997	0.82
274_K	450_E	0.995	0.81
99_S	419_L	0.988	0.81
419_L	427_C	0.987	0.81
117_R	384_Y	0.984	0.81
414_K	418_E	0.980	0.80
302_M	306_A	0.979	0.80
163_T	189_N	0.977	0.80
443_N	446_L	0.972	0.80
57_L	431_P	0.969	0.80
64_L	98_G	0.968	0.80
440_V	443_N	0.968	0.80
100_L	118_V	0.967	0.80
337_A	340_E	0.964	0.79
137_N	331_A	0.964	0.79
247_I	283_A	0.964	0.79
34_K	339_E	0.959	0.79
369_I	446_L	0.955	0.79
24_E	226_H	0.951	0.78
249_V	252_E	0.948	0.78
101_Y	117_R	0.947	0.78
100_L	421_F	0.946	0.78
251_K	255_D	0.944	0.78
449_E	452_K	0.942	0.78
442_D	445_S	0.942	0.78
450_E	458_E	0.941	0.78
28_R	225_T	0.940	0.78
248_R	252_E	0.937	0.77
215_E	269_L	0.935	0.77
139_Q	178_A	0.931	0.77
437_Q	441_Q	0.930	0.77
361_G	471_N	0.929	0.77
76_Y	80_E	0.928	0.77
138_Y	175_G	0.927	0.77
60_A	136_V	0.927	0.77
60_A	131_A	0.922	0.76
434_S	438_Q	0.921	0.76
215_E	245_N	0.919	0.76
262_I	279_M	0.919	0.76
113_E	365_V	0.919	0.76
432_E	438_Q	0.918	0.76
26_Y	126_Q	0.917	0.76
122_L	211_A	0.916	0.76
240_R	244_P	0.912	0.75
260_I	288_A	0.912	0.75
116_M	136_V	0.912	0.75
250_A	254_G	0.906	0.75
230_V	288_A	0.905	0.75
364_K	385_D	0.903	0.75
197_N	434_S	0.902	0.75
223_A	229_C	0.901	0.75
295_D	328_A	0.891	0.74
191_R	195_R	0.888	0.73
150_K	154_G	0.888	0.73
292_A	304_L	0.886	0.73
162_G	166_A	0.884	0.73
245_N	249_V	0.883	0.73
418_E	434_S	0.882	0.73
150_K	184_F	0.881	0.73
104_K	107_E	0.880	0.73
281_D	310_R	0.879	0.73
63_Y	128_I	0.876	0.72
179_A	320_L	0.876	0.72
117_R	362_R	0.876	0.72
28_R	224_E	0.875	0.72
346_D	471_N	0.873	0.72
208_L	212_Y	0.870	0.72
41_F	112_N	0.868	0.72
21_N	83_Y	0.868	0.72
259_F	288_A	0.868	0.72
95_S	98_G	0.865	0.72
40_L	116_M	0.863	0.71
190_V	200_V	0.861	0.71
29_D	224_E	0.860	0.71
428_Y	431_P	0.857	0.71
451_Y	458_E	0.857	0.71
42_F	331_A	0.857	0.71
80_E	193_G	0.856	0.71
105_E	177_R	0.853	0.70
447_L	452_K	0.853	0.70
103_M	416_L	0.851	0.70
213_R	340_E	0.851	0.70
149_I	316_V	0.848	0.70
61_I	428_Y	0.848	0.70
26_Y	36_A	0.846	0.70
158_A	185_S	0.846	0.70
27_W	87_F	0.843	0.70
366_Y	415_D	0.832	0.69
469_W	473_M	0.832	0.69
34_K	340_E	0.831	0.68
233_V	264_L	0.828	0.68
130_T	163_T	0.824	0.68
259_F	285_F	0.824	0.68
382_A	386_E	0.820	0.67
300_T	456_K	0.818	0.67
233_V	244_P	0.815	0.67
423_K	438_Q	0.813	0.67
445_S	452_K	0.812	0.67
245_N	248_R	0.809	0.66
443_N	452_K	0.809	0.66
15_T	20_I	0.807	0.66
213_R	347_T	0.803	0.66
220_K	248_R	0.802	0.66
376_S	460_Y	0.802	0.66
448_W	463_D	0.800	0.65
42_F	52_A	0.797	0.65
440_V	447_L	0.796	0.65
458_E	463_D	0.795	0.65
279_M	282_E	0.793	0.65
204_H	209_V	0.791	0.65
55_A	181_I	0.789	0.64
365_V	417_H	0.789	0.64
253_F	257_I	0.787	0.64
224_E	256_R	0.784	0.64
182_G	440_V	0.783	0.64
50_G	458_E	0.779	0.63
201_S	313_V	0.776	0.63
435_D	438_Q	0.775	0.63
375_H	449_E	0.774	0.63
109_V	140_T	0.774	0.63
430_N	436_I	0.772	0.63
92_R	186_A	0.771	0.63
59_K	139_Q	0.771	0.63
246_A	249_V	0.768	0.62
458_E	461_P	0.762	0.62
135_I	169_M	0.762	0.62
135_I	174_W	0.762	0.62
78_Q	88_I	0.760	0.61
427_C	431_P	0.760	0.61
74_L	92_R	0.759	0.61
242_G	245_N	0.759	0.61
20_I	77_L	0.758	0.61
156_E	312_D	0.754	0.61
94_L	121_P	0.753	0.61
420_I	427_C	0.750	0.60
65_E	430_N	0.749	0.60
76_Y	79_D	0.748	0.60
77_L	193_G	0.743	0.60
62_E	66_N	0.743	0.60
261_G	289_K	0.741	0.60
370_N	377_E	0.741	0.60
19_Q	163_T	0.741	0.60
201_S	291_I	0.740	0.59
432_E	436_I	0.738	0.59
23_A	87_F	0.737	0.59
304_L	311_I	0.736	0.59
13_L	115_I	0.733	0.59
154_G	305_K	0.732	0.59
52_A	329_L	0.727	0.58
368_I	413_A	0.724	0.58
138_Y	166_A	0.723	0.58
62_E	430_N	0.723	0.58
142_I	179_A	0.722	0.58
39_E	117_R	0.721	0.57
211_A	338_I	0.718	0.57
435_D	439_Y	0.715	0.57
275_K	282_E	0.715	0.57
387_Q	390_D	0.714	0.57
19_Q	190_V	0.712	0.56
75_S	78_Q	0.711	0.56
451_Y	460_Y	0.711	0.56
414_K	439_Y	0.709	0.56
421_F	427_C	0.707	0.56
244_P	248_R	0.705	0.56
32_H	123_V	0.704	0.56
25_T	225_T	0.703	0.56
451_Y	461_P	0.702	0.55
166_A	321_I	0.702	0.55
216_Y	249_V	0.701	0.55
170_D	174_W	0.699	0.55
426_L	467_D	0.699	0.55
55_A	143_A	0.697	0.55
38_F	335_L	0.695	0.55
108_L	443_N	0.694	0.55
83_Y	88_I	0.691	0.54
444_L	452_K	0.690	0.54
60_A	128_I	0.690	0.54
24_E	447_L	0.690	0.54
25_T	226_H	0.689	0.54
65_E	421_F	0.685	0.54
60_A	100_L	0.685	0.54
441_Q	445_S	0.681	0.53
35_K	121_P	0.680	0.53
133_L	137_N	0.679	0.53
389_N	393_R	0.673	0.52
159_L	291_I	0.673	0.52
17_L	82_G	0.669	0.52
20_I	83_Y	0.667	0.52
102_S	116_M	0.667	0.52
40_L	331_A	0.666	0.52
262_I	290_V	0.664	0.51
421_F	448_W	0.664	0.51
15_T	19_Q	0.663	0.51
144_T	182_G	0.662	0.51
418_E	467_D	0.661	0.51
95_S	425_I	0.659	0.51
210_Q	235_T	0.659	0.51
17_L	76_Y	0.658	0.51
12_S	63_Y	0.657	0.51
409_T	474_Q	0.656	0.50
27_W	326_Q	0.654	0.50
71_D	89_E	0.652	0.50
271_Y	453_R	0.651	0.50
247_I	262_I	0.651	0.50
249_V	253_F	0.649	0.50
454_I	471_N	0.649	0.50
210_Q	295_D	0.647	0.50
160_E	330_G	0.647	0.50
152_V	302_M	0.646	0.49
270_A	304_L	0.646	0.49
348_I	351_S	0.645	0.49
296_L	301_I	0.645	0.49
435_D	442_D	0.642	0.49
361_G	365_V	0.642	0.49
391_Q	395_R	0.640	0.49
57_L	127_L	0.639	0.49
162_G	321_I	0.638	0.49
72_S	75_S	0.637	0.48
44_R	292_A	0.636	0.48
142_I	320_L	0.636	0.48
24_E	294_S	0.633	0.48
467_D	474_Q	0.633	0.48
257_I	260_I	0.632	0.48
216_Y	253_F	0.631	0.48
98_G	423_K	0.630	0.48
453_R	458_E	0.630	0.48
415_D	419_L	0.629	0.48
171_A	175_G	0.629	0.48
197_N	442_D	0.629	0.48
393_R	410_N	0.628	0.47
387_Q	391_Q	0.627	0.47
53_V	71_D	0.627	0.47
439_Y	442_D	0.626	0.47
224_E	253_F	0.626	0.47
146_A	150_K	0.624	0.47
318_T	325_D	0.624	0.47
47_F	318_T	0.622	0.47
368_I	380_Y	0.622	0.47
419_L	423_K	0.621	0.47
13_L	194_K	0.618	0.46
173_M	191_R	0.618	0.46
153_I	158_A	0.618	0.46
33_E	124_E	0.617	0.46
41_F	449_E	0.617	0.46
450_E	463_D	0.615	0.46
14_H	21_N	0.615	0.46
130_T	330_G	0.614	0.46
453_R	456_K	0.611	0.46
369_I	376_S	0.611	0.46
368_I	389_N	0.611	0.46
138_Y	174_W	0.608	0.45
64_L	222_Y	0.607	0.45
243_M	282_E	0.606	0.45
442_D	446_L	0.605	0.45
445_S	467_D	0.605	0.45
160_E	222_Y	0.604	0.45
303_N	307_Q	0.603	0.45
371_Q	390_D	0.602	0.45
57_L	61_I	0.602	0.45
152_V	184_F	0.600	0.44
149_I	296_L	0.600	0.44
273_S	310_R	0.598	0.44
452_K	460_Y	0.598	0.44
96_F	120_A	0.597	0.44
248_R	256_R	0.595	0.44
376_S	446_L	0.595	0.44
289_K	313_V	0.595	0.44
14_H	163_T	0.593	0.44
140_T	329_L	0.593	0.44
217_T	220_K	0.592	0.44
54_F	115_I	0.592	0.44
29_D	212_Y	0.590	0.43
442_D	470_S	0.590	0.43
73_D	253_F	0.588	0.43
300_T	331_A	0.588	0.43
60_A	135_I	0.588	0.43
140_T	331_A	0.587	0.43
19_Q	130_T	0.587	0.43
95_S	124_E	0.587	0.43
467_D	470_S	0.586	0.43
14_H	107_E	0.586	0.43
383_L	386_E	0.585	0.43
397_F	463_D	0.585	0.43
388_V	413_A	0.584	0.43
167_H	327_P	0.581	0.42
171_A	176_A	0.581	0.42
376_S	447_L	0.578	0.42
151_G	452_K	0.577	0.42
230_V	260_I	0.576	0.42
59_K	168_E	0.574	0.42
410_N	413_A	0.573	0.42
89_E	434_S	0.573	0.42
75_S	85_E	0.572	0.42
194_K	225_T	0.572	0.42
154_G	243_M	0.571	0.41
233_V	283_A	0.570	0.41
209_V	230_V	0.570	0.41
210_Q	460_Y	0.569	0.41
188_S	318_T	0.568	0.41
414_K	435_D	0.568	0.41
426_L	431_P	0.568	0.41
363_K	465_S	0.568	0.41
117_R	295_D	0.568	0.41
57_L	102_S	0.567	0.41
103_M	113_E	0.566	0.41
223_A	253_F	0.565	0.41
124_E	353_N	0.565	0.41
291_I	294_S	0.565	0.41
418_E	442_D	0.564	0.41
357_V	464_L	0.563	0.41
427_C	442_D	0.563	0.41
302_M	455_S	0.563	0.41
397_F	465_S	0.562	0.40
147_A	444_L	0.561	0.40
175_G	179_A	0.561	0.40
14_H	169_M	0.560	0.40
204_H	295_D	0.560	0.40
57_L	104_K	0.559	0.40
296_L	316_V	0.559	0.40
254_G	288_A	0.559	0.40
19_Q	27_W	0.558	0.40
126_Q	227_K	0.558	0.40
304_L	307_Q	0.557	0.40
238_T	300_T	0.556	0.40
430_N	439_Y	0.555	0.40
39_E	321_I	0.555	0.40
430_N	442_D	0.555	0.40
294_S	300_T	0.555	0.40
249_V	254_G	0.555	0.40
77_L	80_E	0.554	0.40
150_K	182_G	0.554	0.40
116_M	132_L	0.554	0.40
152_V	155_D	0.554	0.40
92_R	256_R	0.553	0.40
37_I	314_W	0.553	0.40
59_K	174_W	0.553	0.40
277_R	290_V	0.553	0.40
397_F	464_L	0.551	0.39
434_S	445_S	0.551	0.39
73_D	76_Y	0.551	0.39
97_T	121_P	0.550	0.39
255_D	285_F	0.549	0.39
420_I	431_P	0.549	0.39
243_M	283_A	0.549	0.39
86_D	438_Q	0.549	0.39
436_I	440_V	0.549	0.39
138_Y	167_H	0.549	0.39
238_T	313_V	0.548	0.39
166_A	322_T	0.548	0.39
292_A	357_V	0.548	0.39
27_W	32_H	0.547	0.39
48_E	323_A	0.547	0.39
41_F	474_Q	0.546	0.39
280_L	323_A	0.546	0.39
314_W	325_D	0.545	0.39
97_T	426_L	0.544	0.39
258_N	288_A	0.544	0.39
271_Y	307_Q	0.542	0.38
130_T	172_A	0.542	0.38
425_I	432_E	0.542	0.38
187_T	198_I	0.540	0.38
295_D	319_K	0.540	0.38
25_T	212_Y	0.539	0.38
47_F	325_D	0.539	0.38
182_G	434_S	0.538	0.38
464_L	472_K	0.538	0.38
97_T	410_N	0.538	0.38
270_A	274_K	0.537	0.38
448_W	458_E	0.536	0.38
29_D	225_T	0.536	0.38
295_D	325_D	0.535	0.38
441_Q	444_L	0.534	0.38
372_S	410_N	0.534	0.38
77_L	88_I	0.533	0.38
303_N	306_A	0.533	0.38
423_K	441_Q	0.532	0.37
99_S	429_Q	0.532	0.37
409_T	423_K	0.531	0.37
232_L	235_T	0.531	0.37
258_N	285_F	0.531	0.37
423_K	426_L	0.530	0.37
152_V	310_R	0.530	0.37
231_F	259_F	0.528	0.37
362_R	384_Y	0.527	0.37
471_N	474_Q	0.526	0.37
464_L	468_C	0.525	0.37
193_G	198_I	0.523	0.37
89_E	425_I	0.523	0.37
463_D	469_W	0.523	0.37
42_F	109_V	0.522	0.36
236_Y	416_L	0.522	0.36
238_T	272_L	0.522	0.36
205_A	447_L	0.521	0.36
24_E	81_L	0.521	0.36
74_L	138_Y	0.521	0.36
27_W	47_F	0.521	0.36
465_S	469_W	0.519	0.36
47_F	144_T	0.519	0.36
39_E	336_V	0.519	0.36
380_Y	413_A	0.519	0.36
19_Q	26_Y	0.518	0.36
163_T	188_S	0.518	0.36
415_D	449_E	0.518	0.36
230_V	313_V	0.518	0.36
139_Q	177_R	0.517	0.36
173_M	195_R	0.516	0.36
158_A	320_L	0.516	0.36
52_A	103_M	0.516	0.36
250_A	285_F	0.515	0.36
418_E	445_S	0.515	0.36
418_E	423_K	0.514	0.36
426_L	434_S	0.514	0.36
147_A	151_G	0.513	0.36
172_A	221_K	0.513	0.36
422_E	438_Q	0.512	0.35
228_D	260_I	0.512	0.35
45_L	108_L	0.511	0.35
149_I	184_F	0.511	0.35
33_E	74_L	0.511	0.35
420_I	429_Q	0.510	0.35
271_Y	456_K	0.510	0.35
397_F	466_E	0.510	0.35
137_N	332_V	0.510	0.35
10_S	13_L	0.509	0.35
74_L	211_A	0.508	0.35
155_D	351_S	0.508	0.35
433_I	473_M	0.507	0.35
262_I	273_S	0.506	0.35
188_S	203_T	0.506	0.35
429_Q	442_D	0.505	0.35
459_E	471_N	0.505	0.35
217_T	224_E	0.504	0.35
453_R	463_D	0.504	0.35
354_P	469_W	0.503	0.35
85_E	385_D	0.503	0.35
364_K	384_Y	0.502	0.34
250_A	260_I	0.502	0.34
69_F	74_L	0.502	0.34
146_A	182_G	0.502	0.34
410_N	414_K	0.502	0.34
425_I	438_Q	0.501	0.34
433_I	437_Q	0.501	0.34
31_I	122_L	0.501	0.34
52_A	109_V	0.500	0.34
161_F	186_A	0.500	0.34
81_L	84_H	0.500	0.34

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4yubA	2	0.9041	100	0.194	Contact Map
4mzyA	2	0.9878	100	0.258	Contact Map
4lvfA	2	0.8245	100	0.349	Contact Map
1ybeA	2	0.7143	100	0.415	Contact Map
3os4A	1	0.7224	100	0.419	Contact Map
1vlpA	1	0.7429	100	0.42	Contact Map
2im5A	1	0.7163	100	0.422	Contact Map
1yirA	1	0.7102	100	0.43	Contact Map
4hl7A	4	0.7408	100	0.444	Contact Map
2i14A	5	0.7714	100	0.477	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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