YTDP - BACSU - GREMLIN Contacts

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YTDP - Uncharacterized HTH-type transcriptional regulator YtdP

UniProt:	O32071	Sequences: MGGFMKRSQYKFYYKLITFFCLLSTIPVILVGLFSYEHSQKTAISNVSEEKFDTLQQTQQSIEHILKTVDHSLTHYVSSPPLLRTLSEPLHSDQFQIYNQVNQELNYLQSFDTDLSNMTLVSYTKKWYMNNSGLYRLNTDTLHEAASAYTKQKASRSYWTLEENNHLISTKEGTAENCRYNINLIKQLPLNSTNTKGLAAASIPSCSLVKNMPGYSNANNLFIIDEKGLIILHNNMSDVGESLHNDGFVQKVLAQTANSGQFETVIDRIHYKVTYQKSDYNAWTYFSLVSLPELKKEAKSIGWITFAVCLILLTLSLLFSWLGSRHFYKPIRVLYESFARHGAIQEKQQPPQNEFELIEQSFKQLKDRNDDLEETMKQQATHLQQYFMVRLMLGKLTDEEVDNRFESLGLKQNWRHLALLVLQIDTLNHTPYEKKDMDLLLFAVNSLIERNIPTDKHLAPAVVDKQQATILINQSGTKEEFMAELNETARMIQEKAEAELQLSVSIGISQPFDVLTKAKTAYAEGSEALKYRLKAENKSIIFYEDLDQKKTFKTHFPKQLQHELFDAVKAGDKEKADKCLHAILQAIFTQNTNPYQFQIAIARFLNHVIELMHVLGIELFELEENKMLYDQIFELKTFEDTENWLKNEFIDPMTDKVNARADAQYKNISDNIIHIIHHEFESELTLDEIARRLHYNPNYLSSIFKKEMGISFSEYVSSYRHHMAKSWLAETDMAVKDIAEKLKYKNSQNFIRSFKKLEGITPGNYRQQKRSM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	772 (612)
Sequences:	8819 (7987)
Seq/√Len:	322.8

BACSU - YTDP YESS

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
351_P	356_E	5.253	1.00
340_R	345_Q	3.912	1.00
15_K	353_N	3.709	1.00
33_L	37_E	3.291	1.00
346_E	370_D	3.194	1.00
353_N	356_E	3.081	1.00
13_Y	325_R	2.946	1.00
423_Q	426_T	2.936	1.00
338_F	365_L	2.737	1.00
119_T	200_A	2.682	1.00
410_L	413_N	2.662	1.00
218_A	293_E	2.648	1.00
400_E	404_R	2.640	1.00
324_S	328_Y	2.514	1.00
385_Q	389_V	2.458	1.00
444_V	448_I	2.425	1.00
573_K	576_A	2.404	1.00
153_K	195_T	2.388	1.00
11_K	14_Y	2.358	1.00
576_A	580_L	2.328	1.00
441_L	444_V	2.301	1.00
339_A	357_L	2.290	1.00
346_E	363_K	2.283	1.00
439_L	443_A	2.256	1.00
564_L	567_A	2.245	1.00
338_F	362_F	2.211	1.00
477_T	480_E	2.194	1.00
363_K	366_K	2.178	1.00
474_Q	549_K	2.177	1.00
636_K	639_E	2.173	1.00
444_V	455_D	2.160	1.00
404_R	407_S	2.159	1.00
487_E	491_M	2.140	1.00
270_H	291_L	2.132	1.00
505_S	526_S	2.129	1.00
325_R	329_K	2.117	1.00
635_L	638_F	2.109	1.00
303_W	307_A	2.106	1.00
307_A	311_I	2.086	1.00
174_T	177_N	2.075	1.00
106_N	110_S	2.073	1.00
222_F	286_F	2.072	1.00
613_H	616_G	2.045	1.00
575_K	578_K	2.038	1.00
35_S	305_T	2.022	1.00
277_K	284_T	2.009	1.00
613_H	617_I	1.996	1.00
190_L	194_N	1.944	1.00
471_L	553_K	1.943	1.00
341_H	365_L	1.938	1.00
483_A	547_D	1.931	1.00
603_R	606_N	1.926	1.00
596_Q	599_I	1.919	1.00
390_R	397_T	1.917	1.00
334_L	338_F	1.899	1.00
558_K	562_H	1.897	1.00
532_R	536_E	1.896	1.00
505_S	523_A	1.894	1.00
443_A	446_S	1.893	1.00
320_S	324_S	1.865	1.00
618_E	625_N	1.849	1.00
478_K	545_D	1.843	1.00
341_H	366_K	1.825	1.00
390_R	394_G	1.818	1.00
517_K	520_T	1.786	1.00
430_T	434_K	1.786	1.00
478_K	549_K	1.761	1.00
189_P	195_T	1.754	1.00
446_S	449_E	1.754	1.00
566_D	569_K	1.746	1.00
122_S	126_K	1.736	1.00
425_D	428_N	1.725	1.00
250_Q	254_A	1.725	1.00
527_E	530_K	1.716	1.00
626_K	630_D	1.713	1.00
588_F	592_T	1.705	1.00
481_F	484_E	1.701	1.00
376_M	380_A	1.695	1.00
435_K	439_L	1.690	1.00
461_A	465_K	1.681	1.00
611_L	625_N	1.666	1.00
620_F	623_E	1.665	1.00
602_A	606_N	1.665	1.00
403_N	407_S	1.664	1.00
260_G	275_Y	1.654	1.00
335_Y	361_S	1.648	1.00
150_T	154_A	1.644	1.00
625_N	629_Y	1.628	1.00
437_M	444_V	1.628	1.00
63_E	67_K	1.625	1.00
397_T	401_V	1.625	1.00
32_G	36_Y	1.622	1.00
484_E	487_E	1.613	1.00
586_A	590_Q	1.605	1.00
562_H	565_F	1.566	1.00
32_G	309_C	1.565	1.00
390_R	395_K	1.564	1.00
439_L	442_F	1.558	1.00
346_E	367_D	1.555	1.00
625_N	638_F	1.541	1.00
617_I	620_F	1.530	1.00
339_A	343_A	1.528	1.00
490_R	536_E	1.521	1.00
485_L	542_F	1.521	1.00
142_L	145_A	1.518	1.00
426_T	429_H	1.516	1.00
122_S	125_K	1.515	1.00
73_L	201_A	1.509	1.00
623_E	627_M	1.507	1.00
403_N	406_E	1.505	1.00
229_L	242_S	1.504	1.00
392_M	396_L	1.503	1.00
172_E	183_N	1.502	1.00
607_H	611_L	1.501	1.00
335_Y	357_L	1.499	1.00
463_V	466_Q	1.489	1.00
338_F	358_I	1.482	1.00
371_D	375_T	1.471	1.00
436_D	439_L	1.469	1.00
348_Q	363_K	1.466	1.00
560_L	564_L	1.465	1.00
604_F	611_L	1.465	1.00
472_I	553_K	1.464	1.00
540_I	544_E	1.460	1.00
422_L	426_T	1.455	1.00
12_F	355_F	1.455	1.00
589_T	592_T	1.453	1.00
601_I	611_L	1.453	1.00
450_R	453_P	1.452	1.00
477_T	481_F	1.451	1.00
210_K	213_P	1.448	1.00
606_N	609_I	1.448	1.00
512_F	515_L	1.446	1.00
610_E	613_H	1.443	1.00
620_F	624_E	1.440	1.00
40_Q	44_I	1.434	1.00
385_Q	388_M	1.422	1.00
39_S	301_I	1.422	1.00
446_S	450_R	1.419	1.00
625_N	628_L	1.416	1.00
349_Q	363_K	1.401	1.00
625_N	632_I	1.399	1.00
557_P	564_L	1.398	1.00
478_K	481_F	1.393	1.00
269_I	290_S	1.389	1.00
404_R	413_N	1.385	1.00
573_K	580_L	1.382	1.00
357_L	360_Q	1.380	1.00
179_R	206_C	1.379	1.00
207_S	210_K	1.378	1.00
183_N	202_S	1.377	1.00
585_Q	588_F	1.374	1.00
414_W	421_V	1.373	1.00
358_I	362_F	1.372	1.00
145_A	148_A	1.370	1.00
264_T	271_Y	1.370	1.00
37_E	41_K	1.369	1.00
172_E	202_S	1.368	1.00
616_G	620_F	1.363	1.00
574_E	578_K	1.361	1.00
489_A	495_K	1.360	1.00
225_D	229_L	1.359	1.00
155_S	164_N	1.357	1.00
146_A	152_Q	1.353	1.00
534_K	537_N	1.350	1.00
241_E	245_N	1.348	1.00
467_Q	470_I	1.344	1.00
523_A	526_S	1.340	1.00
606_N	610_E	1.337	1.00
578_K	581_H	1.333	1.00
300_S	304_I	1.330	1.00
299_K	302_G	1.327	1.00
624_E	627_M	1.324	1.00
338_F	361_S	1.322	1.00
384_Q	388_M	1.318	1.00
24_S	27_P	1.316	1.00
291_L	295_K	1.313	1.00
449_E	453_P	1.309	1.00
399_E	403_N	1.306	1.00
565_F	569_K	1.300	1.00
614_V	618_E	1.299	1.00
10_Y	14_Y	1.295	1.00
562_H	566_D	1.295	1.00
375_T	378_Q	1.294	1.00
334_L	358_I	1.292	1.00
567_A	570_A	1.289	1.00
392_M	395_K	1.285	1.00
420_L	425_D	1.283	1.00
34_F	38_H	1.281	1.00
98_Y	102_N	1.281	1.00
595_Y	599_I	1.278	1.00
434_K	437_M	1.264	1.00
150_T	153_K	1.264	1.00
589_T	593_N	1.263	1.00
479_E	550_K	1.260	1.00
220_N	234_N	1.259	1.00
389_V	392_M	1.258	1.00
65_I	69_V	1.256	1.00
601_I	605_L	1.256	1.00
471_L	552_F	1.255	1.00
221_L	287_S	1.253	1.00
608_V	618_E	1.252	1.00
147_S	151_K	1.251	1.00
432_Y	436_D	1.248	1.00
476_G	554_T	1.244	1.00
46_N	50_E	1.242	1.00
39_S	43_A	1.236	1.00
265_V	270_H	1.235	1.00
396_L	400_E	1.234	1.00
362_F	366_K	1.233	1.00
402_D	406_E	1.233	1.00
27_P	312_L	1.232	1.00
334_L	359_E	1.229	1.00
491_M	494_E	1.225	1.00
534_K	538_K	1.217	1.00
306_F	310_L	1.216	1.00
625_N	639_E	1.215	1.00
44_I	48_S	1.213	1.00
51_K	55_L	1.209	1.00
143_H	149_Y	1.205	1.00
488_T	535_A	1.204	1.00
377_K	381_T	1.202	1.00
24_S	316_S	1.201	1.00
437_M	441_L	1.201	1.00
263_E	291_L	1.200	1.00
415_R	419_L	1.199	1.00
582_A	585_Q	1.196	1.00
326_H	329_K	1.194	1.00
210_K	214_G	1.192	1.00
97_I	100_Q	1.190	1.00
31_V	35_S	1.190	1.00
609_I	613_H	1.188	1.00
304_I	307_A	1.186	1.00
339_A	361_S	1.185	1.00
440_L	443_A	1.184	1.00
147_S	150_T	1.183	1.00
444_V	452_I	1.176	1.00
560_L	567_A	1.174	1.00
433_E	437_M	1.173	1.00
489_A	493_Q	1.172	1.00
637_T	640_D	1.169	1.00
145_A	153_K	1.167	1.00
316_S	320_S	1.166	1.00
394_G	397_T	1.164	1.00
120_L	188_L	1.164	1.00
390_R	396_L	1.161	1.00
397_T	400_E	1.160	1.00
271_Y	290_S	1.158	1.00
470_I	474_Q	1.157	1.00
303_W	306_F	1.148	1.00
413_N	416_H	1.147	1.00
438_D	442_F	1.146	1.00
378_Q	382_H	1.146	1.00
115_L	201_A	1.145	1.00
561_Q	564_L	1.145	1.00
366_K	370_D	1.141	1.00
555_H	559_Q	1.138	1.00
448_I	451_N	1.137	1.00
17_I	21_C	1.133	1.00
409_G	412_Q	1.133	1.00
580_L	590_Q	1.132	1.00
376_M	379_Q	1.131	1.00
217_N	293_E	1.128	1.00
13_Y	17_I	1.127	1.00
143_H	146_A	1.126	1.00
417_L	421_V	1.125	1.00
359_E	363_K	1.125	1.00
374_E	377_K	1.124	1.00
349_Q	359_E	1.124	1.00
416_H	419_L	1.117	1.00
560_L	563_E	1.117	1.00
358_I	365_L	1.117	1.00
632_I	639_E	1.116	1.00
475_S	553_K	1.115	1.00
102_N	106_N	1.114	1.00
462_V	466_Q	1.112	1.00
271_Y	288_L	1.112	1.00
339_A	364_Q	1.111	1.00
442_F	446_S	1.111	1.00
149_Y	153_K	1.108	1.00
578_K	582_A	1.103	1.00
531_Y	534_K	1.100	1.00
608_V	611_L	1.100	1.00
444_V	451_N	1.098	1.00
299_K	303_W	1.096	1.00
29_I	33_L	1.093	1.00
248_F	252_V	1.089	1.00
59_Q	63_E	1.087	1.00
453_P	456_K	1.086	1.00
567_A	571_G	1.086	1.00
437_M	447_L	1.085	1.00
636_K	640_D	1.084	1.00
561_Q	565_F	1.084	1.00
607_H	625_N	1.080	1.00
55_L	59_Q	1.079	1.00
530_K	534_K	1.077	1.00
317_L	321_W	1.077	1.00
412_Q	416_H	1.076	1.00
526_S	530_K	1.073	1.00
431_P	438_D	1.072	1.00
373_E	376_M	1.072	1.00
70_D	74_T	1.071	1.00
250_Q	253_L	1.068	1.00
145_A	149_Y	1.067	1.00
627_M	630_D	1.064	1.00
220_N	288_L	1.061	1.00
338_F	341_H	1.061	1.00
475_S	546_L	1.059	1.00
99_N	103_Q	1.058	1.00
179_R	204_P	1.057	1.00
220_N	233_H	1.054	1.00
20_F	320_S	1.053	1.00
185_I	198_L	1.049	1.00
346_E	366_K	1.047	1.00
585_Q	589_T	1.042	1.00
318_L	322_L	1.041	1.00
206_C	210_K	1.040	1.00
474_Q	477_T	1.037	1.00
37_E	40_Q	1.036	1.00
434_K	438_D	1.036	1.00
146_A	149_Y	1.035	1.00
523_A	527_E	1.033	1.00
435_K	438_D	1.033	1.00
490_R	540_I	1.033	1.00
440_L	444_V	1.030	1.00
336_E	339_A	1.028	1.00
437_M	440_L	1.026	1.00
473_N	477_T	1.026	1.00
590_Q	593_N	1.026	1.00
563_E	567_A	1.026	1.00
445_N	449_E	1.025	1.00
472_I	554_T	1.025	1.00
559_Q	562_H	1.024	1.00
146_A	150_T	1.020	1.00
390_R	393_L	1.019	1.00
608_V	625_N	1.014	1.00
251_K	257_A	1.014	1.00
145_A	150_T	1.013	1.00
365_L	369_N	1.013	1.00
67_K	70_D	1.011	1.00
627_M	631_Q	1.009	1.00
59_Q	278_S	1.009	1.00
463_V	467_Q	1.006	1.00
587_I	590_Q	1.003	1.00
592_T	596_Q	1.003	1.00
471_L	556_F	1.002	1.00
55_L	287_S	1.001	1.00
127_W	130_N	0.998	1.00
28_V	31_V	0.997	1.00
451_N	454_T	0.992	1.00
324_S	327_F	0.992	1.00
335_Y	339_A	0.991	1.00
370_D	374_E	0.991	1.00
553_K	557_P	0.990	1.00
614_V	625_N	0.989	1.00
393_L	397_T	0.987	1.00
417_L	424_I	0.986	1.00
613_H	620_F	0.985	1.00
226_E	282_A	0.983	1.00
73_L	186_K	0.982	1.00
430_T	433_E	0.982	1.00
352_Q	356_E	0.980	1.00
416_H	425_D	0.978	1.00
544_E	548_Q	0.977	1.00
605_L	609_I	0.977	1.00
44_I	295_K	0.976	1.00
10_Y	18_T	0.972	1.00
356_E	359_E	0.967	1.00
273_V	286_F	0.967	1.00
416_H	420_L	0.966	1.00
332_R	335_Y	0.964	1.00
190_L	196_K	0.964	1.00
333_V	336_E	0.962	1.00
397_T	402_D	0.961	1.00
367_D	371_D	0.960	1.00
164_N	189_P	0.960	1.00
512_F	521_A	0.959	1.00
438_D	447_L	0.957	1.00
397_T	404_R	0.957	1.00
314_T	318_L	0.956	1.00
148_A	153_K	0.955	1.00
337_S	362_F	0.954	1.00
537_N	541_I	0.953	1.00
401_V	405_F	0.953	1.00
419_L	423_Q	0.953	1.00
390_R	401_V	0.953	1.00
119_T	202_S	0.951	1.00
103_Q	106_N	0.950	1.00
580_L	583_I	0.949	1.00
249_V	252_V	0.948	1.00
349_Q	353_N	0.942	1.00
399_E	402_D	0.939	1.00
170_T	227_K	0.939	1.00
171_K	225_D	0.938	1.00
377_K	380_A	0.935	1.00
36_Y	302_G	0.934	1.00
462_V	465_K	0.934	1.00
423_Q	427_L	0.933	1.00
15_K	326_H	0.932	1.00
396_L	399_E	0.930	1.00
541_I	545_D	0.928	1.00
381_T	384_Q	0.926	1.00
144_E	148_A	0.926	1.00
499_E	506_I	0.924	1.00
107_Y	110_S	0.922	1.00
614_V	617_I	0.922	1.00
464_D	467_Q	0.921	1.00
167_L	185_I	0.921	1.00
557_P	560_L	0.919	1.00
311_I	315_L	0.919	1.00
63_E	280_Y	0.918	1.00
611_L	618_E	0.918	1.00
472_I	557_P	0.918	1.00
248_F	253_L	0.917	1.00
189_P	193_T	0.917	1.00
257_A	260_G	0.916	1.00
372_L	376_M	0.913	1.00
447_L	450_R	0.913	1.00
420_L	427_L	0.912	1.00
401_V	407_S	0.910	1.00
101_V	105_L	0.907	1.00
48_S	52_F	0.907	1.00
151_K	155_S	0.905	1.00
434_K	441_L	0.905	1.00
486_N	490_R	0.902	1.00
32_G	305_T	0.902	1.00
630_D	634_E	0.901	1.00
387_F	390_R	0.901	1.00
501_Q	526_S	0.900	1.00
557_P	567_A	0.900	1.00
481_F	538_K	0.899	1.00
363_K	367_D	0.897	1.00
388_M	392_M	0.895	1.00
514_V	525_G	0.895	1.00
630_D	633_F	0.891	1.00
457_H	460_P	0.890	1.00
235_N	238_D	0.890	1.00
341_H	369_N	0.888	1.00
149_Y	198_L	0.888	1.00
340_R	365_L	0.888	1.00
443_A	447_L	0.886	1.00
612_M	619_L	0.882	1.00
16_L	20_F	0.882	1.00
151_K	154_A	0.880	1.00
71_H	74_T	0.880	1.00
21_C	317_L	0.878	1.00
604_F	608_V	0.878	1.00
144_E	149_Y	0.877	1.00
485_L	536_E	0.875	1.00
433_E	436_D	0.875	1.00
431_P	434_K	0.875	1.00
548_Q	551_T	0.875	1.00
233_H	238_D	0.875	1.00
584_L	590_Q	0.872	1.00
461_A	464_D	0.871	1.00
66_L	69_V	0.871	1.00
556_F	564_L	0.871	1.00
461_A	567_A	0.869	1.00
252_V	286_F	0.867	1.00
222_F	233_H	0.864	1.00
615_L	619_L	0.863	1.00
173_G	178_C	0.863	1.00
487_E	490_R	0.860	1.00
330_P	351_P	0.859	1.00
251_K	254_A	0.856	1.00
532_R	542_F	0.856	1.00
432_Y	435_K	0.854	1.00
146_A	153_K	0.853	1.00
473_N	476_G	0.852	1.00
470_I	473_N	0.851	1.00
538_K	541_I	0.850	1.00
125_K	144_E	0.850	1.00
537_N	540_I	0.849	1.00
100_Q	103_Q	0.848	1.00
298_A	302_G	0.848	1.00
409_G	413_N	0.848	1.00
144_E	147_S	0.846	1.00
374_E	378_Q	0.846	1.00
610_E	614_V	0.845	1.00
411_K	414_W	0.845	1.00
447_L	451_N	0.843	1.00
187_Q	195_T	0.843	1.00
395_K	399_E	0.840	1.00
476_G	480_E	0.839	1.00
406_E	409_G	0.839	1.00
72_S	75_H	0.839	1.00
331_I	358_I	0.835	1.00
451_N	455_D	0.834	1.00
64_H	67_K	0.833	1.00
333_V	337_S	0.833	1.00
372_L	380_A	0.833	1.00
171_K	180_Y	0.833	1.00
604_F	607_H	0.832	1.00
330_P	334_L	0.831	1.00
580_L	594_P	0.830	1.00
272_K	291_L	0.829	1.00
12_F	327_F	0.828	1.00
25_T	313_L	0.828	1.00
302_G	306_F	0.827	1.00
58_T	61_S	0.824	1.00
168_I	184_L	0.824	1.00
557_P	561_Q	0.822	1.00
10_Y	15_K	0.820	1.00
169_S	183_N	0.819	1.00
579_C	590_Q	0.819	1.00
169_S	172_E	0.818	1.00
347_K	363_K	0.817	1.00
448_I	452_I	0.817	1.00
573_K	590_Q	0.817	1.00
593_N	600_A	0.816	1.00
224_I	286_F	0.815	1.00
494_E	506_I	0.814	1.00
421_V	428_N	0.814	1.00
617_I	621_E	0.812	1.00
563_E	566_D	0.810	1.00
599_I	603_R	0.810	1.00
344_I	365_L	0.810	1.00
441_L	455_D	0.805	1.00
420_L	423_Q	0.802	1.00
19_F	323_G	0.802	1.00
50_E	53_D	0.800	1.00
52_F	56_Q	0.799	1.00
181_N	202_S	0.798	1.00
321_W	325_R	0.794	1.00
405_F	408_L	0.793	1.00
35_S	39_S	0.793	1.00
453_P	457_H	0.792	1.00
42_T	46_N	0.792	1.00
69_V	72_S	0.792	1.00
300_S	303_W	0.791	1.00
625_N	636_K	0.790	1.00
77_V	186_K	0.788	1.00
155_S	165_N	0.788	1.00
297_E	300_S	0.785	1.00
631_Q	635_L	0.785	1.00
469_T	561_Q	0.784	1.00
394_G	400_E	0.783	1.00
404_R	410_L	0.783	1.00
555_H	558_K	0.782	1.00
626_K	629_Y	0.782	1.00
480_E	551_T	0.781	1.00
502_L	510_Q	0.778	1.00
379_Q	382_H	0.777	1.00
364_Q	368_R	0.777	1.00
242_S	245_N	0.775	1.00
105_L	109_Q	0.775	1.00
343_A	364_Q	0.773	1.00
413_N	417_L	0.772	1.00
546_L	550_K	0.772	1.00
596_Q	600_A	0.771	1.00
593_N	596_Q	0.771	1.00
149_Y	152_Q	0.770	1.00
141_T	146_A	0.770	1.00
541_I	544_E	0.768	1.00
21_C	27_P	0.768	1.00
497_E	526_S	0.763	0.99
296_K	300_S	0.763	0.99
601_I	604_F	0.763	0.99
67_K	71_H	0.763	0.99
337_S	347_K	0.762	0.99
474_Q	552_F	0.761	0.99
166_H	186_K	0.761	0.99
222_F	288_L	0.760	0.99
543_Y	547_D	0.758	0.99
325_R	332_R	0.756	0.99
117_N	202_S	0.755	0.99
290_S	293_E	0.755	0.99
195_T	198_L	0.754	0.99
68_T	71_H	0.752	0.99
548_Q	552_F	0.748	0.99
472_I	475_S	0.746	0.99
328_Y	332_R	0.743	0.99
557_P	563_E	0.742	0.99
174_T	178_C	0.741	0.99
599_I	602_A	0.740	0.99
590_Q	597_F	0.740	0.99
583_I	590_Q	0.740	0.99
573_K	577_D	0.738	0.99
400_E	403_N	0.735	0.99
631_Q	634_E	0.735	0.99
465_K	468_A	0.734	0.99
365_L	368_R	0.733	0.99
404_R	417_L	0.733	0.99
438_D	444_V	0.733	0.99
366_K	369_N	0.728	0.99
148_A	152_Q	0.725	0.99
395_K	398_D	0.725	0.99
632_I	635_L	0.724	0.99
615_L	618_E	0.724	0.99
424_I	428_N	0.724	0.99
311_I	318_L	0.723	0.99
491_M	495_K	0.723	0.99
490_R	494_E	0.723	0.99
24_S	320_S	0.722	0.99
23_L	27_P	0.721	0.99
529_L	532_R	0.720	0.99
394_G	401_V	0.720	0.99
348_Q	351_P	0.718	0.99
531_Y	538_K	0.718	0.99
494_E	505_S	0.717	0.99
533_L	537_N	0.717	0.99
340_R	343_A	0.716	0.99
298_A	301_I	0.715	0.99
469_T	558_K	0.715	0.99
511_P	521_A	0.713	0.99
142_L	149_Y	0.712	0.99
264_T	273_V	0.711	0.99
382_H	385_Q	0.710	0.99
430_T	437_M	0.710	0.99
364_Q	367_D	0.707	0.99
385_Q	392_M	0.706	0.99
65_I	68_T	0.705	0.99
334_L	362_F	0.705	0.99
628_L	631_Q	0.704	0.99
551_T	555_H	0.704	0.99
436_D	440_L	0.702	0.99
142_L	147_S	0.701	0.99
10_Y	13_Y	0.700	0.99
447_L	454_T	0.699	0.99
330_P	355_F	0.698	0.99
38_H	41_K	0.697	0.99
466_Q	470_I	0.696	0.99
365_L	370_D	0.696	0.99
334_L	347_K	0.696	0.99
469_T	553_K	0.696	0.99
131_N	135_Y	0.695	0.99
421_V	424_I	0.694	0.99
372_L	383_L	0.694	0.99
119_T	127_W	0.694	0.99
501_Q	525_G	0.694	0.99
328_Y	331_I	0.693	0.99
362_F	365_L	0.692	0.99
402_D	407_S	0.691	0.99
251_K	258_N	0.690	0.99
511_P	515_L	0.690	0.99
407_S	413_N	0.689	0.99
566_D	570_A	0.689	0.99
266_I	271_Y	0.686	0.99
440_L	447_L	0.686	0.99
70_D	168_I	0.686	0.99
107_Y	111_F	0.686	0.99
74_T	78_S	0.685	0.99
273_V	288_L	0.684	0.99
602_A	605_L	0.684	0.99
424_I	427_L	0.683	0.99
586_A	594_P	0.682	0.99
417_L	420_L	0.681	0.99
553_K	556_F	0.680	0.99
628_L	632_I	0.679	0.99
479_E	485_L	0.679	0.99
28_V	309_C	0.678	0.99
355_F	359_E	0.677	0.99
11_K	357_L	0.677	0.99
550_K	553_K	0.677	0.99
525_G	528_A	0.676	0.99
121_V	148_A	0.676	0.99
347_K	359_E	0.676	0.99
474_Q	478_K	0.675	0.99
103_Q	107_Y	0.675	0.99
62_I	283_W	0.675	0.99
69_V	115_L	0.674	0.99
349_Q	360_Q	0.673	0.99
185_I	200_A	0.672	0.99
108_L	112_D	0.671	0.99
378_Q	381_T	0.670	0.99
598_Q	602_A	0.670	0.99
475_S	550_K	0.670	0.99
121_V	200_A	0.669	0.99
152_Q	198_L	0.668	0.99
615_L	625_N	0.667	0.99
621_E	624_E	0.667	0.99
263_E	270_H	0.666	0.99
468_A	557_P	0.665	0.99
376_M	383_L	0.665	0.99
188_L	196_K	0.665	0.99
580_L	584_L	0.664	0.99
359_E	362_F	0.664	0.99
485_L	543_Y	0.663	0.99
601_I	608_V	0.658	0.99
9_Q	352_Q	0.657	0.98
611_L	614_V	0.657	0.98
269_I	292_P	0.656	0.98
473_N	558_K	0.655	0.98
304_I	308_V	0.655	0.98
485_L	535_A	0.654	0.98
204_P	207_S	0.654	0.98
310_L	314_T	0.653	0.98
484_E	488_T	0.652	0.98
460_P	463_V	0.652	0.98
49_E	53_D	0.651	0.98
444_V	447_L	0.648	0.98
121_V	143_H	0.647	0.98
141_T	145_A	0.647	0.98
333_V	348_Q	0.647	0.98
430_T	441_L	0.647	0.98
620_F	627_M	0.644	0.98
16_L	324_S	0.644	0.98
441_L	448_I	0.644	0.98
584_L	593_N	0.643	0.98
468_A	560_L	0.642	0.98
441_L	451_N	0.642	0.98
418_A	427_L	0.642	0.98
448_I	454_T	0.638	0.98
184_L	203_I	0.638	0.98
72_S	115_L	0.637	0.98
430_T	580_L	0.636	0.98
170_T	225_D	0.635	0.98
121_V	127_W	0.633	0.98
612_M	615_L	0.630	0.98
237_S	241_E	0.630	0.98
556_F	559_Q	0.627	0.98
401_V	404_R	0.627	0.98
486_N	540_I	0.627	0.98
390_R	398_D	0.625	0.98
569_K	572_D	0.625	0.98
249_V	253_L	0.623	0.98
380_A	387_F	0.623	0.98
391_L	395_K	0.623	0.98
211_N	214_G	0.623	0.98
74_T	186_K	0.622	0.98
394_G	398_D	0.622	0.98
16_L	19_F	0.620	0.98
564_L	568_V	0.620	0.98
381_T	385_Q	0.620	0.98
507_G	528_A	0.618	0.98
393_L	396_L	0.618	0.98
277_K	280_Y	0.618	0.98
386_Y	389_V	0.617	0.98
485_L	532_R	0.617	0.98
130_N	133_G	0.617	0.98
464_D	559_Q	0.616	0.98
73_L	77_V	0.616	0.98
257_A	261_Q	0.615	0.98
373_E	377_K	0.615	0.98
391_L	400_E	0.615	0.98
176_E	179_R	0.615	0.98
140_D	146_A	0.614	0.98
63_E	278_S	0.613	0.98
576_A	590_Q	0.613	0.98
604_F	625_N	0.612	0.98
622_L	629_Y	0.609	0.98
74_T	166_H	0.609	0.98
556_F	560_L	0.604	0.97
261_Q	274_T	0.604	0.97
187_Q	197_G	0.604	0.97
448_I	455_D	0.604	0.97
99_N	102_N	0.602	0.97
142_L	146_A	0.601	0.97
472_I	476_G	0.601	0.97
629_Y	632_I	0.600	0.97
605_L	608_V	0.600	0.97
392_M	399_E	0.599	0.97
465_K	564_L	0.599	0.97
518_A	522_Y	0.598	0.97
301_I	305_T	0.596	0.97
619_L	622_L	0.595	0.97
328_Y	335_Y	0.595	0.97
142_L	148_A	0.595	0.97
330_P	356_E	0.594	0.97
146_A	175_A	0.593	0.97
149_Y	154_A	0.593	0.97
485_L	488_T	0.593	0.97
371_D	374_E	0.588	0.97
213_P	216_S	0.588	0.97
576_A	579_C	0.587	0.97
455_D	461_A	0.587	0.97
121_V	146_A	0.586	0.97
41_K	45_S	0.585	0.97
433_E	441_L	0.584	0.97
380_A	383_L	0.583	0.97
54_T	57_Q	0.583	0.97
525_G	536_E	0.581	0.97
576_A	583_I	0.581	0.97
386_Y	390_R	0.581	0.97
375_T	631_Q	0.580	0.97
329_K	333_V	0.580	0.97
545_D	549_K	0.580	0.97
44_I	47_V	0.580	0.97
363_K	370_D	0.579	0.97
457_H	462_V	0.579	0.97
59_Q	276_Q	0.579	0.97
486_N	536_E	0.578	0.97
69_V	201_A	0.578	0.97
176_E	181_N	0.578	0.97
70_D	184_L	0.577	0.97
217_N	296_K	0.576	0.97
169_S	185_I	0.576	0.97
573_K	579_C	0.576	0.97
431_P	436_D	0.575	0.97
143_H	147_S	0.575	0.97
431_P	435_K	0.574	0.97
233_H	236_M	0.574	0.97
400_E	407_S	0.573	0.96
625_N	635_L	0.573	0.96
387_F	394_G	0.572	0.96
71_H	75_H	0.572	0.96
174_T	202_S	0.571	0.96
326_H	330_P	0.570	0.96
329_K	332_R	0.569	0.96
209_V	213_P	0.569	0.96
129_M	134_L	0.567	0.96
601_I	614_V	0.567	0.96
19_F	316_S	0.567	0.96
484_E	495_K	0.567	0.96
42_T	45_S	0.566	0.96
95_F	99_N	0.565	0.96
335_Y	358_I	0.564	0.96
328_Y	358_I	0.564	0.96
629_Y	638_F	0.563	0.96
441_L	447_L	0.561	0.96
143_H	148_A	0.561	0.96
590_Q	611_L	0.561	0.96
332_R	336_E	0.560	0.96
372_L	375_T	0.560	0.96
360_Q	363_K	0.559	0.96
430_T	438_D	0.559	0.96
619_L	623_E	0.559	0.96
582_A	593_N	0.557	0.96
414_W	417_L	0.557	0.96
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342_G	361_S	0.555	0.96
134_L	138_N	0.555	0.96
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69_V	73_L	0.554	0.96
337_S	341_H	0.553	0.96
118_M	201_A	0.552	0.96
628_L	633_F	0.552	0.96
608_V	612_M	0.550	0.96
590_Q	604_F	0.550	0.96
21_C	25_T	0.550	0.96
515_L	518_A	0.550	0.96
401_V	408_L	0.549	0.96
390_R	404_R	0.547	0.95
445_N	448_I	0.547	0.95
611_L	615_L	0.546	0.95
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495_K	524_E	0.546	0.95
512_F	524_E	0.546	0.95
372_L	377_K	0.546	0.95
423_Q	428_N	0.545	0.95
476_G	551_T	0.545	0.95
76_Y	199_A	0.545	0.95
380_A	384_Q	0.544	0.95
481_F	485_L	0.542	0.95
437_M	455_D	0.542	0.95
144_E	150_T	0.542	0.95
584_L	588_F	0.541	0.95
586_A	593_N	0.541	0.95
141_T	148_A	0.540	0.95
335_Y	355_F	0.540	0.95
27_P	316_S	0.540	0.95
339_A	342_G	0.540	0.95
547_D	554_T	0.539	0.95
13_Y	328_Y	0.539	0.95
277_K	282_A	0.538	0.95
588_F	593_N	0.538	0.95
54_T	58_T	0.537	0.95
58_T	221_L	0.537	0.95
515_L	520_T	0.535	0.95
590_Q	594_P	0.535	0.95
467_Q	552_F	0.533	0.95
515_L	524_E	0.533	0.95
597_F	607_H	0.533	0.95
592_T	595_Y	0.532	0.95
553_K	560_L	0.532	0.95
488_T	529_L	0.532	0.95
142_L	150_T	0.531	0.95
629_Y	633_F	0.530	0.95
183_N	200_A	0.530	0.95
465_K	560_L	0.530	0.95
149_Y	155_S	0.529	0.95
345_Q	365_L	0.529	0.95
580_L	621_E	0.529	0.95
312_L	316_S	0.528	0.94
615_L	622_L	0.528	0.94
414_W	420_L	0.526	0.94
489_A	496_A	0.526	0.94
442_F	445_N	0.526	0.94
481_F	542_F	0.524	0.94
586_A	589_T	0.524	0.94
619_L	625_N	0.524	0.94
468_A	556_F	0.524	0.94
229_L	232_L	0.523	0.94
577_D	581_H	0.523	0.94
503_S	507_G	0.523	0.94
36_Y	40_Q	0.522	0.94
330_P	358_I	0.522	0.94
173_G	180_Y	0.521	0.94
505_S	530_K	0.520	0.94
525_G	531_Y	0.520	0.94
20_F	23_L	0.520	0.94
322_L	326_H	0.518	0.94
337_S	340_R	0.518	0.94
17_I	22_L	0.518	0.94
507_G	510_Q	0.516	0.94
338_F	369_N	0.514	0.94
543_Y	546_L	0.514	0.94
580_L	593_N	0.514	0.94
417_L	428_N	0.513	0.94
404_R	408_L	0.513	0.94
605_L	618_E	0.512	0.94
349_Q	356_E	0.511	0.93
582_A	586_A	0.510	0.93
479_E	483_A	0.507	0.93
418_A	421_V	0.507	0.93
467_Q	559_Q	0.507	0.93
70_D	280_Y	0.506	0.93
384_Q	390_R	0.505	0.93
104_E	107_Y	0.503	0.93
25_T	29_I	0.503	0.93
512_F	517_K	0.503	0.93
486_N	539_S	0.502	0.93
35_S	316_S	0.502	0.93
292_P	295_K	0.502	0.93
507_G	525_G	0.501	0.93
60_Q	63_E	0.501	0.93
622_L	628_L	0.501	0.93
415_R	418_A	0.500	0.93

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4rnhA	2	0.3873	100	0.763	Contact Map
3pjxA	1	0.3886	100	0.769	Contact Map
4j40A	2	0.1775	100	0.77	Contact Map
3gbgA	1	0.3251	100	0.803	Contact Map
1bl0A	1	0.1399	100	0.803	Contact Map
3oioA	1	0.1438	100	0.803	Contact Map
3oouA	1	0.136	100	0.804	Contact Map
3mn2A	1	0.1373	100	0.806	Contact Map
3mklA	1	0.1438	100	0.808	Contact Map
2k9sA	1	0.1373	100	0.809	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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