GREMLIN Database
YTZB - Uncharacterized protein YtzB
UniProt: O32065 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 105 (97)
Sequences: 203 (164)
Seq/√Len: 16.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
34_A89_V4.7821.00
21_R25_M2.8270.98
58_E71_K2.8060.98
42_F76_R2.6480.97
72_T87_V2.5860.96
6_L9_G2.4150.94
93_T99_V2.1320.89
54_Y58_E2.0600.88
32_E61_N1.9800.85
13_G39_K1.9600.85
31_S55_T1.9500.85
42_F46_G1.8050.80
46_G76_R1.7680.78
17_A62_I1.7530.77
42_F47_P1.7090.76
23_Y59_P1.6210.72
55_T58_E1.5960.70
34_A67_V1.5820.70
75_T82_L1.5630.69
82_L85_Y1.4800.64
60_Y71_K1.3870.59
6_L64_G1.3600.58
42_F99_V1.3370.56
7_L37_I1.3370.56
46_G86_E1.3240.56
58_E75_T1.2890.53
38_V99_V1.2800.53
36_R75_T1.2520.51
37_I97_V1.2500.51
8_L48_I1.2430.51
60_Y88_M1.2130.49
34_A65_E1.1880.47
61_N64_G1.1870.47
43_K46_G1.1600.46
71_K88_M1.1600.46
84_Q98_D1.1040.43
78_A85_Y1.0930.42
75_T97_V1.0910.42
21_R97_V1.0840.41
15_C29_I1.0700.41
65_E95_E1.0680.41
47_P84_Q1.0660.40
31_S84_Q1.0580.40
37_I89_V1.0470.39
15_C19_V1.0470.39
4_R15_C1.0390.39
42_F86_E1.0360.39
8_L57_P1.0170.38
29_I84_Q1.0130.37
12_L22_Q1.0110.37
42_F74_I1.0070.37
9_G13_G0.9970.37
38_V84_Q0.9700.35
54_Y75_T0.9630.35
49_D82_L0.9600.35
36_R55_T0.9580.34
10_A18_V0.9530.34
13_G96_I0.9520.34
54_Y71_K0.9440.34
25_M85_Y0.9400.33
58_E69_V0.9320.33
34_A49_D0.9110.32
22_Q43_K0.9100.32
30_S95_E0.9100.32
31_S67_V0.9080.32
18_V62_I0.8990.31
34_A58_E0.8950.31
10_A100_I0.8860.31
36_R40_S0.8690.30
39_K62_I0.8630.30
76_R85_Y0.8610.29
29_I77_S0.8600.29
40_S56_Q0.8590.29
23_Y34_A0.8340.28
9_G16_T0.8290.28
12_L80_G0.8250.28
46_G74_I0.8190.27
25_M77_S0.8180.27
75_T80_G0.8060.27
38_V76_R0.8000.27
59_P64_G0.7900.26
61_N66_T0.7880.26
88_M97_V0.7820.26
11_G14_I0.7800.26
54_Y97_V0.7770.25
47_P82_L0.7650.25
20_V29_I0.7530.24
42_F93_T0.7360.24
47_P76_R0.7280.23
10_A37_I0.7240.23
26_K74_I0.7180.23
57_P60_Y0.7160.23
6_L25_M0.7110.23
76_R82_L0.7110.23
35_L39_K0.7070.22
29_I33_K0.7070.22
45_R63_N0.7040.22
11_G44_Q0.7010.22
5_H89_V0.6980.22
14_I20_V0.6950.22
17_A74_I0.6920.22
7_L96_I0.6840.22
18_V100_I0.6740.21
12_L16_T0.6710.21
32_E39_K0.6670.21
9_G39_K0.6520.20
10_A98_D0.6380.20
17_A95_E0.6370.20
34_A77_S0.6350.20
68_Q92_K0.6330.20
55_T71_K0.6090.19
38_V71_K0.6070.19
41_A44_Q0.6050.19
18_V51_S0.5960.18
78_A83_E0.5950.18
28_Y75_T0.5920.18
14_I80_G0.5920.18
16_T85_Y0.5890.18
22_Q75_T0.5860.18
37_I91_A0.5820.18
92_K97_V0.5760.18
10_A85_Y0.5760.18
60_Y74_I0.5730.17
70_Y73_G0.5730.17
42_F78_A0.5710.17
28_Y44_Q0.5650.17
30_S71_K0.5610.17
9_G74_I0.5610.17
36_R62_I0.5570.17
6_L69_V0.5500.17
4_R47_P0.5450.16
7_L24_V0.5440.16
33_K57_P0.5430.16
64_G81_E0.5340.16
84_Q100_I0.5320.16
19_V36_R0.5320.16
74_I86_E0.5260.16
60_Y69_V0.5200.16
16_T41_A0.5200.16
72_T90_D0.5160.16
9_G59_P0.5120.15
87_V90_D0.5100.15
28_Y92_K0.5080.15
45_R61_N0.5030.15
15_C24_V0.5010.15
32_E58_E0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3nqzA 1 0.9714 94.4 0.863 Contact Map
4k90B 1 0.9619 79.1 0.897 Contact Map
3j61T 1 0.8286 25.5 0.928 Contact Map
3dw0A 1 0.3429 22.5 0.93 Contact Map
4exrA 2 0.8381 20.1 0.931 Contact Map
3ldtA 2 0.7048 17.4 0.933 Contact Map
4w20T 1 0.8286 16.3 0.934 Contact Map
1rypD 1 0.7905 15.5 0.935 Contact Map
4oh0A 1 0.619 15.1 0.935 Contact Map
4zdxA 1 0.5429 15.1 0.935 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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